Amino acid dipepetide frequency for Chanos chanos (Milkfish) (Mugil chanos)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.625AlaAla: 5.625 ± 0.032	1.244AlaCys: 1.244 ± 0.01	3.128AlaAsp: 3.128 ± 0.015	4.712AlaGlu: 4.712 ± 0.03	2.386AlaPhe: 2.386 ± 0.014	4.172AlaGly: 4.172 ± 0.023	1.461AlaHis: 1.461 ± 0.01	2.752AlaIle: 2.752 ± 0.016	3.441AlaLys: 3.441 ± 0.018	6.607AlaLeu: 6.607 ± 0.027	1.602AlaMet: 1.602 ± 0.01	2.21AlaAsn: 2.21 ± 0.013	3.464AlaPro: 3.464 ± 0.025	3.051AlaGln: 3.051 ± 0.018	3.136AlaArg: 3.136 ± 0.015	5.268AlaSer: 5.268 ± 0.024	3.497AlaThr: 3.497 ± 0.02	4.912AlaVal: 4.912 ± 0.02	0.659AlaTrp: 0.659 ± 0.006	1.542AlaTyr: 1.542 ± 0.01	0.001AlaXaa: 0.001 ± 0.0
Cys	1.158CysAla: 1.158 ± 0.01	0.599CysCys: 0.599 ± 0.008	1.08CysAsp: 1.08 ± 0.015	1.256CysGlu: 1.256 ± 0.014	0.825CysPhe: 0.825 ± 0.007	1.494CysGly: 1.494 ± 0.019	0.61CysHis: 0.61 ± 0.007	0.935CysIle: 0.935 ± 0.01	1.171CysLys: 1.171 ± 0.01	2.08CysLeu: 2.08 ± 0.013	0.468CysMet: 0.468 ± 0.005	0.809CysAsn: 0.809 ± 0.008	1.244CysPro: 1.244 ± 0.014	1.0CysGln: 1.0 ± 0.011	1.245CysArg: 1.245 ± 0.013	1.975CysSer: 1.975 ± 0.021	1.168CysThr: 1.168 ± 0.011	1.505CysVal: 1.505 ± 0.013	0.294CysTrp: 0.294 ± 0.004	0.606CysTyr: 0.606 ± 0.006	0.0CysXaa: 0.0 ± 0.0
Asp	2.894AspAla: 2.894 ± 0.014	1.118AspCys: 1.118 ± 0.013	3.085AspAsp: 3.085 ± 0.023	3.809AspGlu: 3.809 ± 0.019	2.125AspPhe: 2.125 ± 0.013	3.615AspGly: 3.615 ± 0.024	1.202AspHis: 1.202 ± 0.01	2.775AspIle: 2.775 ± 0.016	2.737AspLys: 2.737 ± 0.015	5.088AspLeu: 5.088 ± 0.022	1.34AspMet: 1.34 ± 0.01	1.97AspAsn: 1.97 ± 0.014	2.915AspPro: 2.915 ± 0.017	2.022AspGln: 2.022 ± 0.011	2.772AspArg: 2.772 ± 0.017	4.534AspSer: 4.534 ± 0.023	2.765AspThr: 2.765 ± 0.013	3.339AspVal: 3.339 ± 0.019	0.684AspTrp: 0.684 ± 0.007	1.614AspTyr: 1.614 ± 0.012	0.001AspXaa: 0.001 ± 0.0
Glu	4.637GluAla: 4.637 ± 0.026	1.261GluCys: 1.261 ± 0.015	4.51GluAsp: 4.51 ± 0.021	8.132GluGlu: 8.132 ± 0.05	2.04GluPhe: 2.04 ± 0.012	4.34GluGly: 4.34 ± 0.025	1.48GluHis: 1.48 ± 0.011	3.088GluIle: 3.088 ± 0.021	4.96GluLys: 4.96 ± 0.036	6.32GluLeu: 6.32 ± 0.034	1.81GluMet: 1.81 ± 0.013	2.948GluAsn: 2.948 ± 0.015	2.845GluPro: 2.845 ± 0.016	3.196GluGln: 3.196 ± 0.02	4.596GluArg: 4.596 ± 0.033	4.54GluSer: 4.54 ± 0.02	3.567GluThr: 3.567 ± 0.018	4.372GluVal: 4.372 ± 0.024	0.699GluTrp: 0.699 ± 0.007	1.684GluTyr: 1.684 ± 0.013	0.001GluXaa: 0.001 ± 0.0
Phe	1.924PheAla: 1.924 ± 0.014	0.914PheCys: 0.914 ± 0.008	1.816PheAsp: 1.816 ± 0.011	1.952PheGlu: 1.952 ± 0.011	1.515PhePhe: 1.515 ± 0.013	2.247PheGly: 2.247 ± 0.016	0.99PheHis: 0.99 ± 0.009	1.899PheIle: 1.899 ± 0.013	1.803PheLys: 1.803 ± 0.014	3.74PheLeu: 3.74 ± 0.019	0.838PheMet: 0.838 ± 0.007	1.458PheAsn: 1.458 ± 0.012	1.778PhePro: 1.778 ± 0.011	1.615PheGln: 1.615 ± 0.009	1.906PheArg: 1.906 ± 0.013	3.298PheSer: 3.298 ± 0.016	2.233PheThr: 2.233 ± 0.014	2.269PheVal: 2.269 ± 0.013	0.465PheTrp: 0.465 ± 0.006	1.227PheTyr: 1.227 ± 0.009	0.001PheXaa: 0.001 ± 0.0
Gly	3.957GlyAla: 3.957 ± 0.021	1.219GlyCys: 1.219 ± 0.012	3.275GlyAsp: 3.275 ± 0.018	4.211GlyGlu: 4.211 ± 0.026	2.392GlyPhe: 2.392 ± 0.017	5.127GlyGly: 5.127 ± 0.037	1.645GlyHis: 1.645 ± 0.013	2.693GlyIle: 2.693 ± 0.016	3.694GlyLys: 3.694 ± 0.022	5.462GlyLeu: 5.462 ± 0.025	1.568GlyMet: 1.568 ± 0.012	2.539GlyAsn: 2.539 ± 0.015	3.361GlyPro: 3.361 ± 0.046	2.846GlyGln: 2.846 ± 0.019	3.601GlyArg: 3.601 ± 0.017	5.692GlySer: 5.692 ± 0.032	3.626GlyThr: 3.626 ± 0.022	4.061GlyVal: 4.061 ± 0.021	0.759GlyTrp: 0.759 ± 0.008	1.872GlyTyr: 1.872 ± 0.013	0.002GlyXaa: 0.002 ± 0.0
His	1.368HisAla: 1.368 ± 0.01	0.774HisCys: 0.774 ± 0.014	0.98HisAsp: 0.98 ± 0.009	1.219HisGlu: 1.219 ± 0.008	1.033HisPhe: 1.033 ± 0.008	1.586HisGly: 1.586 ± 0.011	0.98HisHis: 0.98 ± 0.012	1.296HisIle: 1.296 ± 0.009	1.283HisLys: 1.283 ± 0.009	2.567HisLeu: 2.567 ± 0.014	0.639HisMet: 0.639 ± 0.006	0.993HisAsn: 0.993 ± 0.009	1.57HisPro: 1.57 ± 0.012	1.21HisGln: 1.21 ± 0.016	1.577HisArg: 1.577 ± 0.009	2.38HisSer: 2.38 ± 0.015	1.583HisThr: 1.583 ± 0.017	1.451HisVal: 1.451 ± 0.01	0.339HisTrp: 0.339 ± 0.005	0.868HisTyr: 0.868 ± 0.008	0.001HisXaa: 0.001 ± 0.0
Ile	2.609IleAla: 2.609 ± 0.014	1.059IleCys: 1.059 ± 0.01	2.163IleAsp: 2.163 ± 0.015	2.553IleGlu: 2.553 ± 0.017	1.845IlePhe: 1.845 ± 0.014	2.35IleGly: 2.35 ± 0.013	1.232IleHis: 1.232 ± 0.014	2.431IleIle: 2.431 ± 0.017	2.563IleLys: 2.563 ± 0.016	4.379IleLeu: 4.379 ± 0.021	1.089IleMet: 1.089 ± 0.009	1.913IleAsn: 1.913 ± 0.011	2.527IlePro: 2.527 ± 0.013	2.254IleGln: 2.254 ± 0.011	2.481IleArg: 2.481 ± 0.012	3.817IleSer: 3.817 ± 0.02	2.829IleThr: 2.829 ± 0.02	2.655IleVal: 2.655 ± 0.014	0.495IleTrp: 0.495 ± 0.006	1.393IleTyr: 1.393 ± 0.01	0.001IleXaa: 0.001 ± 0.0
Lys	3.794LysAla: 3.794 ± 0.021	1.004LysCys: 1.004 ± 0.01	3.277LysAsp: 3.277 ± 0.024	4.853LysGlu: 4.853 ± 0.037	1.665LysPhe: 1.665 ± 0.011	3.314LysGly: 3.314 ± 0.028	1.416LysHis: 1.416 ± 0.01	2.588LysIle: 2.588 ± 0.017	4.487LysLys: 4.487 ± 0.027	5.039LysLeu: 5.039 ± 0.023	1.468LysMet: 1.468 ± 0.012	2.348LysAsn: 2.348 ± 0.014	2.915LysPro: 2.915 ± 0.02	2.573LysGln: 2.573 ± 0.021	3.551LysArg: 3.551 ± 0.015	3.873LysSer: 3.873 ± 0.023	3.289LysThr: 3.289 ± 0.015	3.508LysVal: 3.508 ± 0.02	0.572LysTrp: 0.572 ± 0.007	1.55LysTyr: 1.55 ± 0.013	0.002LysXaa: 0.002 ± 0.0
Leu	6.03LeuAla: 6.03 ± 0.023	2.141LeuCys: 2.141 ± 0.013	4.89LeuAsp: 4.89 ± 0.021	6.588LeuGlu: 6.588 ± 0.042	3.36LeuPhe: 3.36 ± 0.017	5.161LeuGly: 5.161 ± 0.025	2.6LeuHis: 2.6 ± 0.015	3.863LeuIle: 3.863 ± 0.017	5.66LeuLys: 5.66 ± 0.026	9.549LeuLeu: 9.549 ± 0.039	2.09LeuMet: 2.09 ± 0.013	3.661LeuAsn: 3.661 ± 0.016	5.147LeuPro: 5.147 ± 0.025	5.355LeuGln: 5.355 ± 0.03	5.729LeuArg: 5.729 ± 0.021	8.182LeuSer: 8.182 ± 0.031	5.249LeuThr: 5.249 ± 0.02	5.342LeuVal: 5.342 ± 0.023	1.01LeuTrp: 1.01 ± 0.009	2.619LeuTyr: 2.619 ± 0.014	0.002LeuXaa: 0.002 ± 0.0
Met	1.981MetAla: 1.981 ± 0.011	0.458MetCys: 0.458 ± 0.005	1.466MetAsp: 1.466 ± 0.009	2.033MetGlu: 2.033 ± 0.013	0.865MetPhe: 0.865 ± 0.007	1.475MetGly: 1.475 ± 0.012	0.507MetHis: 0.507 ± 0.005	0.887MetIle: 0.887 ± 0.008	1.508MetLys: 1.508 ± 0.01	2.024MetLeu: 2.024 ± 0.011	0.688MetMet: 0.688 ± 0.007	0.964MetAsn: 0.964 ± 0.008	1.162MetPro: 1.162 ± 0.013	1.012MetGln: 1.012 ± 0.009	1.207MetArg: 1.207 ± 0.01	1.866MetSer: 1.866 ± 0.011	1.324MetThr: 1.324 ± 0.009	1.535MetVal: 1.535 ± 0.01	0.248MetTrp: 0.248 ± 0.004	0.659MetTyr: 0.659 ± 0.006	0.001MetXaa: 0.001 ± 0.0
Asn	2.292AsnAla: 2.292 ± 0.014	0.864AsnCys: 0.864 ± 0.01	1.789AsnAsp: 1.789 ± 0.013	2.19AsnGlu: 2.19 ± 0.012	1.418AsnPhe: 1.418 ± 0.01	2.892AsnGly: 2.892 ± 0.019	0.978AsnHis: 0.978 ± 0.009	2.124AsnIle: 2.124 ± 0.013	2.197AsnLys: 2.197 ± 0.013	3.654AsnLeu: 3.654 ± 0.015	1.038AsnMet: 1.038 ± 0.008	1.763AsnAsn: 1.763 ± 0.015	2.317AsnPro: 2.317 ± 0.012	1.744AsnGln: 1.744 ± 0.014	1.993AsnArg: 1.993 ± 0.012	3.3AsnSer: 3.3 ± 0.017	2.298AsnThr: 2.298 ± 0.013	2.377AsnVal: 2.377 ± 0.015	0.449AsnTrp: 0.449 ± 0.005	1.137AsnTyr: 1.137 ± 0.009	0.0AsnXaa: 0.0 ± 0.0
Pro	4.013ProAla: 4.013 ± 0.026	1.014ProCys: 1.014 ± 0.013	2.873ProAsp: 2.873 ± 0.015	3.845ProGlu: 3.845 ± 0.018	1.761ProPhe: 1.761 ± 0.013	4.174ProGly: 4.174 ± 0.047	1.506ProHis: 1.506 ± 0.013	1.893ProIle: 1.893 ± 0.013	2.668ProLys: 2.668 ± 0.026	4.688ProLeu: 4.688 ± 0.02	1.089ProMet: 1.089 ± 0.009	1.98ProAsn: 1.98 ± 0.013	5.452ProPro: 5.452 ± 0.057	2.625ProGln: 2.625 ± 0.021	2.737ProArg: 2.737 ± 0.018	5.443ProSer: 5.443 ± 0.03	3.166ProThr: 3.166 ± 0.02	3.9ProVal: 3.9 ± 0.021	0.538ProTrp: 0.538 ± 0.007	1.478ProTyr: 1.478 ± 0.016	0.001ProXaa: 0.001 ± 0.0
Gln	3.233GlnAla: 3.233 ± 0.019	0.986GlnCys: 0.986 ± 0.017	2.364GlnAsp: 2.364 ± 0.012	3.544GlnGlu: 3.544 ± 0.022	1.401GlnPhe: 1.401 ± 0.009	2.756GlnGly: 2.756 ± 0.018	1.321GlnHis: 1.321 ± 0.011	2.007GlnIle: 2.007 ± 0.013	2.637GlnLys: 2.637 ± 0.02	4.393GlnLeu: 4.393 ± 0.024	1.155GlnMet: 1.155 ± 0.009	1.899GlnAsn: 1.899 ± 0.013	2.534GlnPro: 2.534 ± 0.02	3.246GlnGln: 3.246 ± 0.039	3.137GlnArg: 3.137 ± 0.026	3.554GlnSer: 3.554 ± 0.021	2.631GlnThr: 2.631 ± 0.016	2.697GlnVal: 2.697 ± 0.014	0.544GlnTrp: 0.544 ± 0.006	1.283GlnTyr: 1.283 ± 0.01	0.001GlnXaa: 0.001 ± 0.0
Arg	3.43ArgAla: 3.43 ± 0.013	1.159ArgCys: 1.159 ± 0.012	3.004ArgAsp: 3.004 ± 0.015	4.251ArgGlu: 4.251 ± 0.026	1.943ArgPhe: 1.943 ± 0.01	3.468ArgGly: 3.468 ± 0.022	1.538ArgHis: 1.538 ± 0.011	2.469ArgIle: 2.469 ± 0.017	3.667ArgLys: 3.667 ± 0.018	5.213ArgLeu: 5.213 ± 0.021	1.345ArgMet: 1.345 ± 0.01	2.165ArgAsn: 2.165 ± 0.013	2.901ArgPro: 2.901 ± 0.017	2.707ArgGln: 2.707 ± 0.016	4.335ArgArg: 4.335 ± 0.024	4.429ArgSer: 4.429 ± 0.029	2.921ArgThr: 2.921 ± 0.015	3.395ArgVal: 3.395 ± 0.018	0.638ArgTrp: 0.638 ± 0.007	1.603ArgTyr: 1.603 ± 0.011	0.001ArgXaa: 0.001 ± 0.0
Ser	5.565SerAla: 5.565 ± 0.024	1.781SerCys: 1.781 ± 0.014	4.389SerAsp: 4.389 ± 0.02	5.148SerGlu: 5.148 ± 0.022	2.969SerPhe: 2.969 ± 0.019	5.629SerGly: 5.629 ± 0.025	2.148SerHis: 2.148 ± 0.015	3.317SerIle: 3.317 ± 0.016	4.069SerLys: 4.069 ± 0.018	7.995SerLeu: 7.995 ± 0.031	1.838SerMet: 1.838 ± 0.013	2.991SerAsn: 2.991 ± 0.018	5.768SerPro: 5.768 ± 0.031	3.848SerGln: 3.848 ± 0.028	4.42SerArg: 4.42 ± 0.025	9.658SerSer: 9.658 ± 0.057	4.877SerThr: 4.877 ± 0.029	5.585SerVal: 5.585 ± 0.022	0.936SerTrp: 0.936 ± 0.008	2.195SerTyr: 2.195 ± 0.014	0.002SerXaa: 0.002 ± 0.0
Thr	4.102ThrAla: 4.102 ± 0.022	1.283ThrCys: 1.283 ± 0.015	2.993ThrAsp: 2.993 ± 0.017	4.065ThrGlu: 4.065 ± 0.023	2.092ThrPhe: 2.092 ± 0.013	3.855ThrGly: 3.855 ± 0.021	1.442ThrHis: 1.442 ± 0.011	2.455ThrIle: 2.455 ± 0.014	2.66ThrLys: 2.66 ± 0.016	5.478ThrLeu: 5.478 ± 0.023	1.233ThrMet: 1.233 ± 0.009	1.934ThrAsn: 1.934 ± 0.011	3.737ThrPro: 3.737 ± 0.023	2.498ThrGln: 2.498 ± 0.016	2.449ThrArg: 2.449 ± 0.013	4.704ThrSer: 4.704 ± 0.03	3.507ThrThr: 3.507 ± 0.055	4.416ThrVal: 4.416 ± 0.024	0.653ThrTrp: 0.653 ± 0.007	1.483ThrTyr: 1.483 ± 0.011	0.001ThrXaa: 0.001 ± 0.0
Val	4.061ValAla: 4.061 ± 0.019	1.668ValCys: 1.668 ± 0.015	3.25ValAsp: 3.25 ± 0.02	4.215ValGlu: 4.215 ± 0.025	2.627ValPhe: 2.627 ± 0.017	3.57ValGly: 3.57 ± 0.019	1.529ValHis: 1.529 ± 0.009	3.095ValIle: 3.095 ± 0.015	3.716ValLys: 3.716 ± 0.022	6.224ValLeu: 6.224 ± 0.024	1.529ValMet: 1.529 ± 0.01	2.539ValAsn: 2.539 ± 0.016	3.427ValPro: 3.427 ± 0.019	2.816ValGln: 2.816 ± 0.016	3.312ValArg: 3.312 ± 0.016	5.343ValSer: 5.343 ± 0.02	4.113ValThr: 4.113 ± 0.024	4.365ValVal: 4.365 ± 0.024	0.773ValTrp: 0.773 ± 0.007	1.87ValTyr: 1.87 ± 0.012	0.001ValXaa: 0.001 ± 0.0
Trp	0.691TrpAla: 0.691 ± 0.008	0.241TrpCys: 0.241 ± 0.004	0.653TrpAsp: 0.653 ± 0.007	0.754TrpGlu: 0.754 ± 0.007	0.449TrpPhe: 0.449 ± 0.005	0.625TrpGly: 0.625 ± 0.008	0.28TrpHis: 0.28 ± 0.005	0.582TrpIle: 0.582 ± 0.007	0.686TrpLys: 0.686 ± 0.007	1.116TrpLeu: 1.116 ± 0.009	0.346TrpMet: 0.346 ± 0.005	0.516TrpAsn: 0.516 ± 0.006	0.416TrpPro: 0.416 ± 0.006	0.465TrpGln: 0.465 ± 0.006	0.712TrpArg: 0.712 ± 0.006	0.913TrpSer: 0.913 ± 0.009	0.672TrpThr: 0.672 ± 0.007	0.69TrpVal: 0.69 ± 0.006	0.185TrpTrp: 0.185 ± 0.004	0.354TrpTyr: 0.354 ± 0.005	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.505TyrAla: 1.505 ± 0.011	0.731TyrCys: 0.731 ± 0.007	1.419TyrAsp: 1.419 ± 0.01	1.696TyrGlu: 1.696 ± 0.01	1.178TyrPhe: 1.178 ± 0.009	1.752TyrGly: 1.752 ± 0.012	0.833TyrHis: 0.833 ± 0.014	1.489TyrIle: 1.489 ± 0.011	1.476TyrLys: 1.476 ± 0.012	2.61TyrLeu: 2.61 ± 0.016	0.694TyrMet: 0.694 ± 0.007	1.212TyrAsn: 1.212 ± 0.011	1.364TyrPro: 1.364 ± 0.012	1.238TyrGln: 1.238 ± 0.009	1.687TyrArg: 1.687 ± 0.011	2.356TyrSer: 2.356 ± 0.013	1.724TyrThr: 1.724 ± 0.012	1.669TyrVal: 1.669 ± 0.012	0.404TyrTrp: 0.404 ± 0.006	0.989TyrTyr: 0.989 ± 0.009	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.001XaaAla: 0.001 ± 0.0	0.001XaaCys: 0.001 ± 0.0	0.001XaaAsp: 0.001 ± 0.0	0.001XaaGlu: 0.001 ± 0.0	0.001XaaPhe: 0.001 ± 0.0	0.001XaaGly: 0.001 ± 0.0	0.001XaaHis: 0.001 ± 0.0	0.001XaaIle: 0.001 ± 0.0	0.001XaaLys: 0.001 ± 0.0	0.002XaaLeu: 0.002 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.001XaaAsn: 0.001 ± 0.0	0.001XaaPro: 0.001 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.001XaaArg: 0.001 ± 0.0	0.001XaaSer: 0.001 ± 0.0	0.001XaaThr: 0.001 ± 0.0	0.002XaaVal: 0.002 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.001XaaTyr: 0.001 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 28996 proteins (17709472 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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