Amino acid dipepetide frequency for Nitratifractor salsuginis (strain DSM 16511 / JCM 12458 / E9I37-1)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.642AlaAla: 7.642 ± 0.168	0.772AlaCys: 0.772 ± 0.037	3.738AlaAsp: 3.738 ± 0.077	5.575AlaGlu: 5.575 ± 0.111	3.351AlaPhe: 3.351 ± 0.066	5.976AlaGly: 5.976 ± 0.103	1.747AlaHis: 1.747 ± 0.056	5.513AlaIle: 5.513 ± 0.093	5.715AlaLys: 5.715 ± 0.111	9.896AlaLeu: 9.896 ± 0.138	2.543AlaMet: 2.543 ± 0.062	2.479AlaAsn: 2.479 ± 0.075	3.191AlaPro: 3.191 ± 0.08	2.901AlaGln: 2.901 ± 0.086	4.621AlaArg: 4.621 ± 0.087	4.075AlaSer: 4.075 ± 0.083	3.822AlaThr: 3.822 ± 0.078	5.524AlaVal: 5.524 ± 0.119	0.916AlaTrp: 0.916 ± 0.042	2.811AlaTyr: 2.811 ± 0.064	0.0AlaXaa: 0.0 ± 0.0
Cys	0.632CysAla: 0.632 ± 0.032	0.111CysCys: 0.111 ± 0.014	0.617CysAsp: 0.617 ± 0.036	0.625CysGlu: 0.625 ± 0.028	0.311CysPhe: 0.311 ± 0.022	0.804CysGly: 0.804 ± 0.038	0.301CysHis: 0.301 ± 0.029	0.455CysIle: 0.455 ± 0.028	0.46CysLys: 0.46 ± 0.029	0.56CysLeu: 0.56 ± 0.031	0.187CysMet: 0.187 ± 0.017	0.325CysAsn: 0.325 ± 0.023	0.534CysPro: 0.534 ± 0.035	0.262CysGln: 0.262 ± 0.022	0.639CysArg: 0.639 ± 0.036	0.566CysSer: 0.566 ± 0.033	0.452CysThr: 0.452 ± 0.025	0.464CysVal: 0.464 ± 0.028	0.073CysTrp: 0.073 ± 0.01	0.358CysTyr: 0.358 ± 0.025	0.0CysXaa: 0.0 ± 0.0
Asp	4.228AspAla: 4.228 ± 0.09	0.434AspCys: 0.434 ± 0.028	2.566AspAsp: 2.566 ± 0.081	4.627AspGlu: 4.627 ± 0.097	2.822AspPhe: 2.822 ± 0.066	3.706AspGly: 3.706 ± 0.124	0.923AspHis: 0.923 ± 0.038	3.392AspIle: 3.392 ± 0.071	2.917AspLys: 2.917 ± 0.067	5.746AspLeu: 5.746 ± 0.08	1.222AspMet: 1.222 ± 0.044	1.72AspAsn: 1.72 ± 0.069	3.126AspPro: 3.126 ± 0.084	1.382AspGln: 1.382 ± 0.054	3.839AspArg: 3.839 ± 0.083	2.424AspSer: 2.424 ± 0.071	2.59AspThr: 2.59 ± 0.066	2.996AspVal: 2.996 ± 0.072	0.634AspTrp: 0.634 ± 0.034	2.352AspTyr: 2.352 ± 0.066	0.0AspXaa: 0.0 ± 0.0
Glu	7.739GluAla: 7.739 ± 0.133	0.666GluCys: 0.666 ± 0.035	3.416GluAsp: 3.416 ± 0.084	7.761GluGlu: 7.761 ± 0.158	2.582GluPhe: 2.582 ± 0.063	5.423GluGly: 5.423 ± 0.101	1.71GluHis: 1.71 ± 0.054	5.635GluIle: 5.635 ± 0.116	5.819GluLys: 5.819 ± 0.125	7.644GluLeu: 7.644 ± 0.135	2.034GluMet: 2.034 ± 0.065	2.837GluAsn: 2.837 ± 0.071	2.65GluPro: 2.65 ± 0.069	2.129GluGln: 2.129 ± 0.071	5.309GluArg: 5.309 ± 0.103	3.735GluSer: 3.735 ± 0.079	3.327GluThr: 3.327 ± 0.071	4.551GluVal: 4.551 ± 0.092	0.77GluTrp: 0.77 ± 0.034	2.562GluTyr: 2.562 ± 0.059	0.0GluXaa: 0.0 ± 0.0
Phe	3.51PheAla: 3.51 ± 0.074	0.388PheCys: 0.388 ± 0.026	2.988PheAsp: 2.988 ± 0.073	3.051PheGlu: 3.051 ± 0.074	2.208PhePhe: 2.208 ± 0.07	3.483PheGly: 3.483 ± 0.076	0.902PheHis: 0.902 ± 0.04	2.627PheIle: 2.627 ± 0.064	2.17PheLys: 2.17 ± 0.059	4.556PheLeu: 4.556 ± 0.101	0.867PheMet: 0.867 ± 0.039	1.465PheAsn: 1.465 ± 0.049	1.536PhePro: 1.536 ± 0.055	0.926PheGln: 0.926 ± 0.041	2.254PheArg: 2.254 ± 0.06	2.693PheSer: 2.693 ± 0.071	2.151PheThr: 2.151 ± 0.057	2.931PheVal: 2.931 ± 0.069	0.507PheTrp: 0.507 ± 0.032	1.769PheTyr: 1.769 ± 0.059	0.0PheXaa: 0.0 ± 0.0
Gly	5.398GlyAla: 5.398 ± 0.104	0.872GlyCys: 0.872 ± 0.043	3.773GlyAsp: 3.773 ± 0.099	5.169GlyGlu: 5.169 ± 0.104	3.296GlyPhe: 3.296 ± 0.077	5.161GlyGly: 5.161 ± 0.119	1.507GlyHis: 1.507 ± 0.053	5.307GlyIle: 5.307 ± 0.088	5.069GlyLys: 5.069 ± 0.096	6.369GlyLeu: 6.369 ± 0.113	2.161GlyMet: 2.161 ± 0.065	2.386GlyAsn: 2.386 ± 0.08	1.832GlyPro: 1.832 ± 0.053	1.728GlyGln: 1.728 ± 0.055	3.85GlyArg: 3.85 ± 0.099	3.966GlySer: 3.966 ± 0.085	3.51GlyThr: 3.51 ± 0.095	5.153GlyVal: 5.153 ± 0.094	0.992GlyTrp: 0.992 ± 0.041	3.012GlyTyr: 3.012 ± 0.067	0.0GlyXaa: 0.0 ± 0.0
His	1.519HisAla: 1.519 ± 0.048	0.258HisCys: 0.258 ± 0.022	0.969HisAsp: 0.969 ± 0.037	1.133HisGlu: 1.133 ± 0.043	1.179HisPhe: 1.179 ± 0.042	1.49HisGly: 1.49 ± 0.049	0.618HisHis: 0.618 ± 0.038	1.495HisIle: 1.495 ± 0.044	1.138HisLys: 1.138 ± 0.046	2.433HisLeu: 2.433 ± 0.07	0.482HisMet: 0.482 ± 0.029	0.818HisAsn: 0.818 ± 0.037	1.463HisPro: 1.463 ± 0.05	0.72HisGln: 0.72 ± 0.034	1.533HisArg: 1.533 ± 0.06	1.27HisSer: 1.27 ± 0.044	1.133HisThr: 1.133 ± 0.041	0.923HisVal: 0.923 ± 0.036	0.296HisTrp: 0.296 ± 0.02	1.148HisTyr: 1.148 ± 0.046	0.0HisXaa: 0.0 ± 0.0
Ile	6.298IleAla: 6.298 ± 0.121	0.522IleCys: 0.522 ± 0.029	4.96IleAsp: 4.96 ± 0.095	5.715IleGlu: 5.715 ± 0.109	2.958IlePhe: 2.958 ± 0.082	4.58IleGly: 4.58 ± 0.091	1.406IleHis: 1.406 ± 0.044	3.811IleIle: 3.811 ± 0.093	3.613IleLys: 3.613 ± 0.084	7.113IleLeu: 7.113 ± 0.116	1.156IleMet: 1.156 ± 0.044	2.237IleAsn: 2.237 ± 0.067	3.118IlePro: 3.118 ± 0.07	1.658IleGln: 1.658 ± 0.057	4.05IleArg: 4.05 ± 0.084	3.486IleSer: 3.486 ± 0.086	3.239IleThr: 3.239 ± 0.059	4.757IleVal: 4.757 ± 0.09	0.571IleTrp: 0.571 ± 0.034	2.371IleTyr: 2.371 ± 0.071	0.0IleXaa: 0.0 ± 0.0
Lys	5.553LysAla: 5.553 ± 0.104	0.371LysCys: 0.371 ± 0.028	2.871LysAsp: 2.871 ± 0.068	6.317LysGlu: 6.317 ± 0.126	1.874LysPhe: 1.874 ± 0.062	4.087LysGly: 4.087 ± 0.092	1.279LysHis: 1.279 ± 0.044	4.768LysIle: 4.768 ± 0.091	5.569LysLys: 5.569 ± 0.118	5.813LysLeu: 5.813 ± 0.106	1.821LysMet: 1.821 ± 0.052	2.593LysAsn: 2.593 ± 0.073	2.554LysPro: 2.554 ± 0.069	1.737LysGln: 1.737 ± 0.053	4.049LysArg: 4.049 ± 0.089	3.323LysSer: 3.323 ± 0.074	2.852LysThr: 2.852 ± 0.067	4.093LysVal: 4.093 ± 0.081	0.598LysTrp: 0.598 ± 0.034	2.104LysTyr: 2.104 ± 0.056	0.0LysXaa: 0.0 ± 0.0
Leu	8.492LeuAla: 8.492 ± 0.143	0.856LeuCys: 0.856 ± 0.04	5.678LeuAsp: 5.678 ± 0.103	8.153LeuGlu: 8.153 ± 0.134	5.063LeuPhe: 5.063 ± 0.106	7.19LeuGly: 7.19 ± 0.113	2.371LeuHis: 2.371 ± 0.066	6.54LeuIle: 6.54 ± 0.117	7.04LeuLys: 7.04 ± 0.12	11.296LeuLeu: 11.296 ± 0.169	2.519LeuMet: 2.519 ± 0.052	3.407LeuAsn: 3.407 ± 0.073	4.849LeuPro: 4.849 ± 0.088	3.315LeuGln: 3.315 ± 0.087	5.975LeuArg: 5.975 ± 0.114	6.742LeuSer: 6.742 ± 0.111	4.507LeuThr: 4.507 ± 0.089	5.564LeuVal: 5.564 ± 0.108	1.178LeuTrp: 1.178 ± 0.051	3.96LeuTyr: 3.96 ± 0.084	0.0LeuXaa: 0.0 ± 0.0
Met	2.188MetAla: 2.188 ± 0.057	0.154MetCys: 0.154 ± 0.014	1.197MetAsp: 1.197 ± 0.038	1.924MetGlu: 1.924 ± 0.062	0.745MetPhe: 0.745 ± 0.037	1.886MetGly: 1.886 ± 0.059	0.534MetHis: 0.534 ± 0.031	1.972MetIle: 1.972 ± 0.054	2.061MetLys: 2.061 ± 0.059	2.424MetLeu: 2.424 ± 0.059	0.751MetMet: 0.751 ± 0.036	0.938MetAsn: 0.938 ± 0.041	1.178MetPro: 1.178 ± 0.037	0.867MetGln: 0.867 ± 0.04	1.409MetArg: 1.409 ± 0.044	1.485MetSer: 1.485 ± 0.05	1.225MetThr: 1.225 ± 0.043	1.509MetVal: 1.509 ± 0.053	0.157MetTrp: 0.157 ± 0.016	0.472MetTyr: 0.472 ± 0.024	0.0MetXaa: 0.0 ± 0.0
Asn	2.714AsnAla: 2.714 ± 0.079	0.276AsnCys: 0.276 ± 0.022	1.932AsnAsp: 1.932 ± 0.077	2.278AsnGlu: 2.278 ± 0.063	1.507AsnPhe: 1.507 ± 0.055	2.509AsnGly: 2.509 ± 0.085	0.683AsnHis: 0.683 ± 0.032	2.424AsnIle: 2.424 ± 0.071	1.807AsnLys: 1.807 ± 0.06	3.354AsnLeu: 3.354 ± 0.084	0.732AsnMet: 0.732 ± 0.036	1.246AsnAsn: 1.246 ± 0.073	2.227AsnPro: 2.227 ± 0.063	0.881AsnGln: 0.881 ± 0.046	2.352AsnArg: 2.352 ± 0.065	1.685AsnSer: 1.685 ± 0.061	1.553AsnThr: 1.553 ± 0.06	2.169AsnVal: 2.169 ± 0.063	0.289AsnTrp: 0.289 ± 0.026	1.414AsnTyr: 1.414 ± 0.05	0.0AsnXaa: 0.0 ± 0.0
Pro	3.327ProAla: 3.327 ± 0.081	0.32ProCys: 0.32 ± 0.023	2.625ProAsp: 2.625 ± 0.061	4.207ProGlu: 4.207 ± 0.09	1.978ProPhe: 1.978 ± 0.057	2.956ProGly: 2.956 ± 0.075	1.081ProHis: 1.081 ± 0.043	2.649ProIle: 2.649 ± 0.073	2.883ProLys: 2.883 ± 0.076	4.221ProLeu: 4.221 ± 0.087	0.943ProMet: 0.943 ± 0.038	1.346ProAsn: 1.346 ± 0.051	1.574ProPro: 1.574 ± 0.056	1.208ProGln: 1.208 ± 0.04	2.178ProArg: 2.178 ± 0.061	2.371ProSer: 2.371 ± 0.069	2.048ProThr: 2.048 ± 0.059	3.151ProVal: 3.151 ± 0.085	0.537ProTrp: 0.537 ± 0.029	1.58ProTyr: 1.58 ± 0.049	0.0ProXaa: 0.0 ± 0.0
Gln	2.609GlnAla: 2.609 ± 0.073	0.233GlnCys: 0.233 ± 0.019	1.081GlnAsp: 1.081 ± 0.049	2.356GlnGlu: 2.356 ± 0.074	0.951GlnPhe: 0.951 ± 0.041	1.882GlnGly: 1.882 ± 0.058	0.575GlnHis: 0.575 ± 0.028	2.151GlnIle: 2.151 ± 0.062	2.49GlnLys: 2.49 ± 0.067	2.636GlnLeu: 2.636 ± 0.067	0.851GlnMet: 0.851 ± 0.04	1.235GlnAsn: 1.235 ± 0.049	1.105GlnPro: 1.105 ± 0.039	0.972GlnGln: 0.972 ± 0.051	1.859GlnArg: 1.859 ± 0.053	1.685GlnSer: 1.685 ± 0.053	1.449GlnThr: 1.449 ± 0.047	1.728GlnVal: 1.728 ± 0.056	0.317GlnTrp: 0.317 ± 0.022	0.777GlnTyr: 0.777 ± 0.033	0.0GlnXaa: 0.0 ± 0.0
Arg	4.068ArgAla: 4.068 ± 0.076	0.564ArgCys: 0.564 ± 0.033	3.042ArgAsp: 3.042 ± 0.065	5.179ArgGlu: 5.179 ± 0.112	3.074ArgPhe: 3.074 ± 0.076	3.502ArgGly: 3.502 ± 0.084	1.622ArgHis: 1.622 ± 0.057	4.583ArgIle: 4.583 ± 0.099	3.757ArgLys: 3.757 ± 0.08	6.623ArgLeu: 6.623 ± 0.121	1.633ArgMet: 1.633 ± 0.05	1.989ArgAsn: 1.989 ± 0.056	2.279ArgPro: 2.279 ± 0.066	2.202ArgGln: 2.202 ± 0.061	4.334ArgArg: 4.334 ± 0.106	3.272ArgSer: 3.272 ± 0.076	2.229ArgThr: 2.229 ± 0.061	3.584ArgVal: 3.584 ± 0.078	0.747ArgTrp: 0.747 ± 0.037	3.012ArgTyr: 3.012 ± 0.076	0.0ArgXaa: 0.0 ± 0.0
Ser	4.248SerAla: 4.248 ± 0.081	0.469SerCys: 0.469 ± 0.026	3.083SerAsp: 3.083 ± 0.074	3.479SerGlu: 3.479 ± 0.074	2.589SerPhe: 2.589 ± 0.07	4.302SerGly: 4.302 ± 0.093	1.133SerHis: 1.133 ± 0.046	3.59SerIle: 3.59 ± 0.081	3.15SerLys: 3.15 ± 0.074	5.875SerLeu: 5.875 ± 0.1	1.336SerMet: 1.336 ± 0.044	1.799SerAsn: 1.799 ± 0.071	2.302SerPro: 2.302 ± 0.067	1.541SerGln: 1.541 ± 0.052	3.361SerArg: 3.361 ± 0.087	3.056SerSer: 3.056 ± 0.081	2.603SerThr: 2.603 ± 0.068	3.315SerVal: 3.315 ± 0.078	0.648SerTrp: 0.648 ± 0.034	2.142SerTyr: 2.142 ± 0.063	0.0SerXaa: 0.0 ± 0.0
Thr	3.636ThrAla: 3.636 ± 0.077	0.387ThrCys: 0.387 ± 0.027	2.481ThrAsp: 2.481 ± 0.081	2.647ThrGlu: 2.647 ± 0.07	2.023ThrPhe: 2.023 ± 0.06	3.617ThrGly: 3.617 ± 0.084	1.143ThrHis: 1.143 ± 0.042	3.376ThrIle: 3.376 ± 0.082	2.14ThrLys: 2.14 ± 0.068	6.166ThrLeu: 6.166 ± 0.106	1.032ThrMet: 1.032 ± 0.041	1.3ThrAsn: 1.3 ± 0.053	2.993ThrPro: 2.993 ± 0.079	1.444ThrGln: 1.444 ± 0.051	2.584ThrArg: 2.584 ± 0.059	2.116ThrSer: 2.116 ± 0.057	2.248ThrThr: 2.248 ± 0.077	3.57ThrVal: 3.57 ± 0.075	0.423ThrTrp: 0.423 ± 0.025	1.469ThrTyr: 1.469 ± 0.055	0.0ThrXaa: 0.0 ± 0.0
Val	5.415ValAla: 5.415 ± 0.111	0.626ValCys: 0.626 ± 0.034	3.774ValAsp: 3.774 ± 0.08	4.855ValGlu: 4.855 ± 0.112	2.284ValPhe: 2.284 ± 0.066	4.366ValGly: 4.366 ± 0.076	1.29ValHis: 1.29 ± 0.041	4.356ValIle: 4.356 ± 0.091	3.876ValLys: 3.876 ± 0.077	6.317ValLeu: 6.317 ± 0.113	1.649ValMet: 1.649 ± 0.047	2.197ValAsn: 2.197 ± 0.066	2.704ValPro: 2.704 ± 0.065	1.585ValGln: 1.585 ± 0.055	3.429ValArg: 3.429 ± 0.07	3.714ValSer: 3.714 ± 0.073	3.581ValThr: 3.581 ± 0.084	4.518ValVal: 4.518 ± 0.093	0.65ValTrp: 0.65 ± 0.031	1.891ValTyr: 1.891 ± 0.058	0.0ValXaa: 0.0 ± 0.0
Trp	0.724TrpAla: 0.724 ± 0.034	0.095TrpCys: 0.095 ± 0.012	0.512TrpAsp: 0.512 ± 0.029	0.696TrpGlu: 0.696 ± 0.031	0.485TrpPhe: 0.485 ± 0.028	0.815TrpGly: 0.815 ± 0.04	0.298TrpHis: 0.298 ± 0.021	0.902TrpIle: 0.902 ± 0.038	0.636TrpLys: 0.636 ± 0.032	1.422TrpLeu: 1.422 ± 0.059	0.415TrpMet: 0.415 ± 0.026	0.336TrpAsn: 0.336 ± 0.026	0.314TrpPro: 0.314 ± 0.023	0.42TrpGln: 0.42 ± 0.023	0.634TrpArg: 0.634 ± 0.032	0.55TrpSer: 0.55 ± 0.032	0.428TrpThr: 0.428 ± 0.03	0.69TrpVal: 0.69 ± 0.036	0.173TrpTrp: 0.173 ± 0.02	0.368TrpTyr: 0.368 ± 0.031	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.869TyrAla: 2.869 ± 0.077	0.36TyrCys: 0.36 ± 0.023	2.344TyrAsp: 2.344 ± 0.074	2.552TyrGlu: 2.552 ± 0.059	1.702TyrPhe: 1.702 ± 0.055	2.777TyrGly: 2.777 ± 0.072	0.892TyrHis: 0.892 ± 0.034	2.069TyrIle: 2.069 ± 0.056	1.915TyrLys: 1.915 ± 0.056	4.231TyrLeu: 4.231 ± 0.103	0.742TyrMet: 0.742 ± 0.03	1.381TyrAsn: 1.381 ± 0.057	1.657TyrPro: 1.657 ± 0.052	1.065TyrGln: 1.065 ± 0.042	3.034TyrArg: 3.034 ± 0.073	1.807TyrSer: 1.807 ± 0.053	1.85TyrThr: 1.85 ± 0.069	1.888TyrVal: 1.888 ± 0.064	0.436TyrTrp: 0.436 ± 0.022	1.558TyrTyr: 1.558 ± 0.061	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2076 proteins (630847 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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