Canine distemper virus (strain Onderstepoort) (CDV)

Taxonomy: Viruses; Riboviria; Orthornavirae; Negarnaviricota; Haploviricotina; Monjiviricetes; Mononegavirales; Paramyxoviridae; Orthoparamyxovirinae; Morbillivirus; Canine morbillivirus

Average proteome isoelectric point is 7.01

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 7 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|O89326|O89326_CDVO Matrix protein OS=Canine distemper virus (strain Onderstepoort) OX=11233 PE=4 SV=1
MM1 pKa = 8.2AEE3 pKa = 3.69EE4 pKa = 3.84QAYY7 pKa = 9.61HH8 pKa = 5.38VSKK11 pKa = 10.9GLEE14 pKa = 3.92CLKK17 pKa = 10.59ALRR20 pKa = 11.84EE21 pKa = 4.01NPPDD25 pKa = 3.3IEE27 pKa = 4.62EE28 pKa = 4.1IQEE31 pKa = 4.01VSSLRR36 pKa = 11.84DD37 pKa = 3.28QTCNPGQEE45 pKa = 4.05NGTTGMQEE53 pKa = 4.16EE54 pKa = 4.73EE55 pKa = 4.27DD56 pKa = 3.95SQNLDD61 pKa = 3.42EE62 pKa = 4.54SHH64 pKa = 6.74EE65 pKa = 4.09PTKK68 pKa = 10.71GSNYY72 pKa = 9.5VGHH75 pKa = 6.68VPQNNPGCGEE85 pKa = 4.14RR86 pKa = 11.84NTALVEE92 pKa = 4.02AEE94 pKa = 4.06RR95 pKa = 11.84PPRR98 pKa = 11.84EE99 pKa = 4.69DD100 pKa = 3.04IQPGPGIRR108 pKa = 11.84CDD110 pKa = 3.25HH111 pKa = 6.72VYY113 pKa = 10.8DD114 pKa = 4.13HH115 pKa = 7.06SGEE118 pKa = 4.14EE119 pKa = 3.94VKK121 pKa = 11.05GIEE124 pKa = 4.43DD125 pKa = 3.86ADD127 pKa = 4.13SLVVPAGTVGNRR139 pKa = 11.84GFEE142 pKa = 4.04RR143 pKa = 11.84GEE145 pKa = 4.06GSLDD149 pKa = 4.26DD150 pKa = 3.79STEE153 pKa = 4.11DD154 pKa = 3.24SGEE157 pKa = 4.26DD158 pKa = 3.59YY159 pKa = 11.42SEE161 pKa = 4.91GNASSNWGYY170 pKa = 11.52SFGLKK175 pKa = 9.29PDD177 pKa = 3.53RR178 pKa = 11.84AADD181 pKa = 3.34VSMLMEE187 pKa = 4.64EE188 pKa = 4.45EE189 pKa = 4.38LSALLRR195 pKa = 11.84TSRR198 pKa = 11.84NVGIQKK204 pKa = 10.0RR205 pKa = 11.84DD206 pKa = 3.17GKK208 pKa = 8.63TLQFPHH214 pKa = 6.76NPEE217 pKa = 3.84GKK219 pKa = 8.16TRR221 pKa = 11.84DD222 pKa = 4.04PEE224 pKa = 4.44CGSIKK229 pKa = 10.48KK230 pKa = 8.55GTEE233 pKa = 3.79EE234 pKa = 4.29RR235 pKa = 11.84SVSHH239 pKa = 6.08GMGIVAGSTSGATQSALKK257 pKa = 9.2STGGSSEE264 pKa = 4.18PSVSAGNVRR273 pKa = 11.84QPAMNAKK280 pKa = 7.64MTQKK284 pKa = 10.56CKK286 pKa = 10.82LEE288 pKa = 4.57SGTQLPPRR296 pKa = 11.84TSNEE300 pKa = 3.8AEE302 pKa = 4.09SDD304 pKa = 3.81SEE306 pKa = 4.24YY307 pKa = 11.08DD308 pKa = 4.06DD309 pKa = 4.78EE310 pKa = 5.56LFSEE314 pKa = 4.24IQEE317 pKa = 3.84IRR319 pKa = 11.84SAITKK324 pKa = 8.37LTEE327 pKa = 4.38DD328 pKa = 3.47NQAILTKK335 pKa = 10.44LDD337 pKa = 3.45TLLLLKK343 pKa = 11.03GEE345 pKa = 4.15TDD347 pKa = 3.76SIKK350 pKa = 10.85KK351 pKa = 10.14QISKK355 pKa = 10.63QNIAISTIEE364 pKa = 3.89GHH366 pKa = 6.69LSSIMIAIPGFGKK379 pKa = 9.05DD380 pKa = 3.53TGDD383 pKa = 3.17PTANVDD389 pKa = 3.43INPEE393 pKa = 3.82LRR395 pKa = 11.84PIIGRR400 pKa = 11.84DD401 pKa = 3.02SGRR404 pKa = 11.84ALAEE408 pKa = 4.04VLKK411 pKa = 10.82QPASSRR417 pKa = 11.84GNRR420 pKa = 11.84KK421 pKa = 10.0DD422 pKa = 3.24SGITLGSKK430 pKa = 10.24GQLLRR435 pKa = 11.84DD436 pKa = 3.91LQLKK440 pKa = 9.99PIDD443 pKa = 4.57KK444 pKa = 9.63EE445 pKa = 4.16SSSAIGYY452 pKa = 8.67KK453 pKa = 10.4PKK455 pKa = 9.89DD456 pKa = 3.54TAPSKK461 pKa = 10.96AVLASLIRR469 pKa = 11.84SSRR472 pKa = 11.84VDD474 pKa = 3.13QSHH477 pKa = 5.66KK478 pKa = 10.8HH479 pKa = 5.55NMLALLKK486 pKa = 10.42NIKK489 pKa = 10.53GDD491 pKa = 3.77DD492 pKa = 3.97NLNEE496 pKa = 4.73FYY498 pKa = 11.4QMVKK502 pKa = 10.48SITHH506 pKa = 6.25AA507 pKa = 3.6

Molecular weight: 54.75 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|Q77Z86|Q77Z86_CDVO Protein C OS=Canine distemper virus (strain Onderstepoort) OX=11233 PE=3 SV=1
MM1 pKa = 7.5SAKK4 pKa = 9.56GWNASKK10 pKa = 10.3PSEE13 pKa = 4.61RR14 pKa = 11.84ILLTLRR20 pKa = 11.84RR21 pKa = 11.84FKK23 pKa = 10.8RR24 pKa = 11.84SAASEE29 pKa = 4.33TKK31 pKa = 10.06PATQAKK37 pKa = 9.67RR38 pKa = 11.84MEE40 pKa = 4.26PQACRR45 pKa = 11.84KK46 pKa = 9.59RR47 pKa = 11.84RR48 pKa = 11.84TLRR51 pKa = 11.84ISMNHH56 pKa = 5.75TSQQKK61 pKa = 9.31DD62 pKa = 3.24QTMSAMYY69 pKa = 9.99LKK71 pKa = 10.34IIRR74 pKa = 11.84DD75 pKa = 3.57VEE77 pKa = 4.08NAILRR82 pKa = 11.84LWRR85 pKa = 11.84RR86 pKa = 11.84SGPLEE91 pKa = 3.8RR92 pKa = 11.84TSNQDD97 pKa = 2.93LEE99 pKa = 4.58YY100 pKa = 10.89DD101 pKa = 3.79VIMFMITAVKK111 pKa = 10.1RR112 pKa = 11.84LRR114 pKa = 11.84EE115 pKa = 4.26SKK117 pKa = 9.8MLTVSWYY124 pKa = 9.9LQALSVIEE132 pKa = 4.25DD133 pKa = 3.33SRR135 pKa = 11.84EE136 pKa = 3.75EE137 pKa = 4.15KK138 pKa = 9.81EE139 pKa = 4.17ALMIALRR146 pKa = 11.84ILAKK150 pKa = 10.28IIPKK154 pKa = 10.22EE155 pKa = 3.92MLHH158 pKa = 5.65LTGDD162 pKa = 3.34ILSALNRR169 pKa = 11.84TEE171 pKa = 3.78QLMM174 pKa = 3.81

Molecular weight: 20.26 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

7

0

7

4989

174

2184

712.7

80.01

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.612 ± 0.374

1.744 ± 0.215

5.272 ± 0.332

5.652 ± 0.526

3.387 ± 0.539

6.254 ± 0.446

2.485 ± 0.392

8.138 ± 0.347

5.232 ± 0.229

10.563 ± 0.384

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.445 ± 0.234

4.37 ± 0.102

4.39 ± 0.275

3.848 ± 0.431

5.993 ± 0.245

8.88 ± 0.458

5.833 ± 0.261

5.492 ± 0.295

1.002 ± 0.143

3.407 ± 0.417
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski