Amino acid dipepetide frequency for Mytilinidion resinicola

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.174AlaAla: 9.174 ± 0.06	1.171AlaCys: 1.171 ± 0.014	4.157AlaAsp: 4.157 ± 0.026	5.236AlaGlu: 5.236 ± 0.034	3.3AlaPhe: 3.3 ± 0.026	5.785AlaGly: 5.785 ± 0.033	1.886AlaHis: 1.886 ± 0.016	4.41AlaIle: 4.41 ± 0.031	4.264AlaLys: 4.264 ± 0.029	8.049AlaLeu: 8.049 ± 0.043	1.942AlaMet: 1.942 ± 0.019	2.903AlaAsn: 2.903 ± 0.023	4.992AlaPro: 4.992 ± 0.034	3.283AlaGln: 3.283 ± 0.026	5.133AlaArg: 5.133 ± 0.028	7.426AlaSer: 7.426 ± 0.039	5.356AlaThr: 5.356 ± 0.029	5.479AlaVal: 5.479 ± 0.032	1.268AlaTrp: 1.268 ± 0.016	2.271AlaTyr: 2.271 ± 0.021	0.0AlaXaa: 0.0 ± 0.0
Cys	1.014CysAla: 1.014 ± 0.012	0.301CysCys: 0.301 ± 0.007	0.686CysAsp: 0.686 ± 0.01	0.663CysGlu: 0.663 ± 0.01	0.566CysPhe: 0.566 ± 0.009	1.036CysGly: 1.036 ± 0.014	0.36CysHis: 0.36 ± 0.008	0.75CysIle: 0.75 ± 0.011	0.586CysLys: 0.586 ± 0.01	1.301CysLeu: 1.301 ± 0.016	0.283CysMet: 0.283 ± 0.006	0.462CysAsn: 0.462 ± 0.009	0.726CysPro: 0.726 ± 0.011	0.466CysGln: 0.466 ± 0.01	0.856CysArg: 0.856 ± 0.012	1.004CysSer: 1.004 ± 0.013	0.773CysThr: 0.773 ± 0.012	0.868CysVal: 0.868 ± 0.013	0.242CysTrp: 0.242 ± 0.006	0.392CysTyr: 0.392 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	4.733AspAla: 4.733 ± 0.03	0.656AspCys: 0.656 ± 0.012	3.935AspAsp: 3.935 ± 0.038	4.322AspGlu: 4.322 ± 0.037	2.217AspPhe: 2.217 ± 0.021	3.92AspGly: 3.92 ± 0.028	1.209AspHis: 1.209 ± 0.015	2.951AspIle: 2.951 ± 0.021	2.255AspLys: 2.255 ± 0.02	4.953AspLeu: 4.953 ± 0.031	1.209AspMet: 1.209 ± 0.012	1.691AspAsn: 1.691 ± 0.018	3.228AspPro: 3.228 ± 0.028	1.732AspGln: 1.732 ± 0.018	2.929AspArg: 2.929 ± 0.025	3.983AspSer: 3.983 ± 0.026	2.921AspThr: 2.921 ± 0.021	3.627AspVal: 3.627 ± 0.026	0.943AspTrp: 0.943 ± 0.013	1.551AspTyr: 1.551 ± 0.016	0.0AspXaa: 0.0 ± 0.0
Glu	5.527GluAla: 5.527 ± 0.036	0.689GluCys: 0.689 ± 0.01	4.185GluAsp: 4.185 ± 0.033	5.558GluGlu: 5.558 ± 0.047	1.915GluPhe: 1.915 ± 0.016	3.999GluGly: 3.999 ± 0.028	1.477GluHis: 1.477 ± 0.016	3.003GluIle: 3.003 ± 0.021	3.849GluLys: 3.849 ± 0.037	5.305GluLeu: 5.305 ± 0.032	1.473GluMet: 1.473 ± 0.018	2.186GluAsn: 2.186 ± 0.019	2.713GluPro: 2.713 ± 0.027	2.301GluGln: 2.301 ± 0.021	4.094GluArg: 4.094 ± 0.03	4.185GluSer: 4.185 ± 0.031	3.342GluThr: 3.342 ± 0.023	3.714GluVal: 3.714 ± 0.028	0.944GluTrp: 0.944 ± 0.012	1.684GluTyr: 1.684 ± 0.016	0.0GluXaa: 0.0 ± 0.0
Phe	3.15PheAla: 3.15 ± 0.025	0.616PheCys: 0.616 ± 0.011	2.195PheAsp: 2.195 ± 0.02	2.215PheGlu: 2.215 ± 0.019	1.638PhePhe: 1.638 ± 0.02	2.859PheGly: 2.859 ± 0.027	0.916PheHis: 0.916 ± 0.012	1.794PheIle: 1.794 ± 0.018	1.605PheLys: 1.605 ± 0.017	3.536PheLeu: 3.536 ± 0.025	0.777PheMet: 0.777 ± 0.011	1.385PheAsn: 1.385 ± 0.016	1.988PhePro: 1.988 ± 0.019	1.395PheGln: 1.395 ± 0.016	2.033PheArg: 2.033 ± 0.019	3.006PheSer: 3.006 ± 0.022	2.182PheThr: 2.182 ± 0.018	2.335PheVal: 2.335 ± 0.021	0.668PheTrp: 0.668 ± 0.01	1.061PheTyr: 1.061 ± 0.015	0.0PheXaa: 0.0 ± 0.0
Gly	5.402GlyAla: 5.402 ± 0.035	0.969GlyCys: 0.969 ± 0.013	3.49GlyAsp: 3.49 ± 0.025	3.793GlyGlu: 3.793 ± 0.023	2.804GlyPhe: 2.804 ± 0.024	5.837GlyGly: 5.837 ± 0.043	1.658GlyHis: 1.658 ± 0.018	3.47GlyIle: 3.47 ± 0.027	3.567GlyLys: 3.567 ± 0.026	6.051GlyLeu: 6.051 ± 0.031	1.646GlyMet: 1.646 ± 0.016	2.442GlyAsn: 2.442 ± 0.021	3.259GlyPro: 3.259 ± 0.028	2.371GlyGln: 2.371 ± 0.021	4.225GlyArg: 4.225 ± 0.033	5.35GlySer: 5.35 ± 0.033	3.901GlyThr: 3.901 ± 0.028	4.461GlyVal: 4.461 ± 0.035	1.252GlyTrp: 1.252 ± 0.014	2.081GlyTyr: 2.081 ± 0.018	0.0GlyXaa: 0.0 ± 0.0
His	1.977HisAla: 1.977 ± 0.017	0.378HisCys: 0.378 ± 0.008	1.337HisAsp: 1.337 ± 0.016	1.35HisGlu: 1.35 ± 0.016	0.977HisPhe: 0.977 ± 0.012	1.688HisGly: 1.688 ± 0.018	0.911HisHis: 0.911 ± 0.013	1.242HisIle: 1.242 ± 0.013	0.977HisLys: 0.977 ± 0.014	2.35HisLeu: 2.35 ± 0.02	0.481HisMet: 0.481 ± 0.009	0.849HisAsn: 0.849 ± 0.011	1.747HisPro: 1.747 ± 0.018	0.986HisGln: 0.986 ± 0.013	1.607HisArg: 1.607 ± 0.014	1.915HisSer: 1.915 ± 0.018	1.397HisThr: 1.397 ± 0.015	1.419HisVal: 1.419 ± 0.015	0.37HisTrp: 0.37 ± 0.007	0.713HisTyr: 0.713 ± 0.01	0.0HisXaa: 0.0 ± 0.0
Ile	4.3IleAla: 4.3 ± 0.027	0.792IleCys: 0.792 ± 0.011	2.743IleAsp: 2.743 ± 0.023	2.881IleGlu: 2.881 ± 0.024	1.975IlePhe: 1.975 ± 0.021	3.163IleGly: 3.163 ± 0.025	1.217IleHis: 1.217 ± 0.014	2.486IleIle: 2.486 ± 0.023	2.219IleLys: 2.219 ± 0.02	4.541IleLeu: 4.541 ± 0.029	0.982IleMet: 0.982 ± 0.013	1.736IleAsn: 1.736 ± 0.016	3.112IlePro: 3.112 ± 0.024	1.857IleGln: 1.857 ± 0.015	2.851IleArg: 2.851 ± 0.021	3.902IleSer: 3.902 ± 0.026	2.915IleThr: 2.915 ± 0.026	3.089IleVal: 3.089 ± 0.021	0.764IleTrp: 0.764 ± 0.012	1.43IleTyr: 1.43 ± 0.015	0.0IleXaa: 0.0 ± 0.0
Lys	4.477LysAla: 4.477 ± 0.033	0.547LysCys: 0.547 ± 0.01	2.851LysAsp: 2.851 ± 0.022	3.579LysGlu: 3.579 ± 0.033	1.49LysPhe: 1.49 ± 0.013	3.185LysGly: 3.185 ± 0.025	1.206LysHis: 1.206 ± 0.012	2.288LysIle: 2.288 ± 0.021	3.432LysLys: 3.432 ± 0.037	4.176LysLeu: 4.176 ± 0.027	1.036LysMet: 1.036 ± 0.015	1.728LysAsn: 1.728 ± 0.019	2.811LysPro: 2.811 ± 0.026	1.79LysGln: 1.79 ± 0.021	3.532LysArg: 3.532 ± 0.03	3.499LysSer: 3.499 ± 0.028	2.925LysThr: 2.925 ± 0.023	2.837LysVal: 2.837 ± 0.023	0.72LysTrp: 0.72 ± 0.009	1.38LysTyr: 1.38 ± 0.014	0.0LysXaa: 0.0 ± 0.0
Leu	8.01LeuAla: 8.01 ± 0.043	1.317LeuCys: 1.317 ± 0.015	5.101LeuAsp: 5.101 ± 0.035	5.708LeuGlu: 5.708 ± 0.037	3.322LeuPhe: 3.322 ± 0.028	5.922LeuGly: 5.922 ± 0.031	2.407LeuHis: 2.407 ± 0.021	3.95LeuIle: 3.95 ± 0.029	4.352LeuLys: 4.352 ± 0.028	8.554LeuLeu: 8.554 ± 0.054	1.72LeuMet: 1.72 ± 0.017	3.129LeuAsn: 3.129 ± 0.021	5.666LeuPro: 5.666 ± 0.032	3.784LeuGln: 3.784 ± 0.025	6.037LeuArg: 6.037 ± 0.036	7.279LeuSer: 7.279 ± 0.035	4.792LeuThr: 4.792 ± 0.032	5.388LeuVal: 5.388 ± 0.034	1.273LeuTrp: 1.273 ± 0.013	2.354LeuTyr: 2.354 ± 0.021	0.0LeuXaa: 0.0 ± 0.0
Met	2.176MetAla: 2.176 ± 0.018	0.265MetCys: 0.265 ± 0.007	1.212MetAsp: 1.212 ± 0.014	1.295MetGlu: 1.295 ± 0.015	0.726MetPhe: 0.726 ± 0.01	1.416MetGly: 1.416 ± 0.015	0.5MetHis: 0.5 ± 0.009	0.944MetIle: 0.944 ± 0.013	1.033MetLys: 1.033 ± 0.012	1.844MetLeu: 1.844 ± 0.019	0.532MetMet: 0.532 ± 0.009	0.753MetAsn: 0.753 ± 0.011	1.302MetPro: 1.302 ± 0.018	0.818MetGln: 0.818 ± 0.013	1.304MetArg: 1.304 ± 0.014	1.792MetSer: 1.792 ± 0.015	1.252MetThr: 1.252 ± 0.013	1.243MetVal: 1.243 ± 0.014	0.283MetTrp: 0.283 ± 0.007	0.516MetTyr: 0.516 ± 0.008	0.0MetXaa: 0.0 ± 0.0
Asn	3.179AsnAla: 3.179 ± 0.023	0.468AsnCys: 0.468 ± 0.009	1.85AsnAsp: 1.85 ± 0.016	1.961AsnGlu: 1.961 ± 0.018	1.365AsnPhe: 1.365 ± 0.016	2.844AsnGly: 2.844 ± 0.025	0.862AsnHis: 0.862 ± 0.011	1.987AsnIle: 1.987 ± 0.018	1.484AsnLys: 1.484 ± 0.016	3.192AsnLeu: 3.192 ± 0.022	0.8AsnMet: 0.8 ± 0.012	1.322AsnAsn: 1.322 ± 0.017	2.444AsnPro: 2.444 ± 0.022	1.251AsnGln: 1.251 ± 0.015	1.883AsnArg: 1.883 ± 0.017	2.695AsnSer: 2.695 ± 0.023	2.204AsnThr: 2.204 ± 0.018	2.209AsnVal: 2.209 ± 0.02	0.564AsnTrp: 0.564 ± 0.009	1.01AsnTyr: 1.01 ± 0.014	0.0AsnXaa: 0.0 ± 0.0
Pro	5.383ProAla: 5.383 ± 0.036	0.576ProCys: 0.576 ± 0.01	3.078ProAsp: 3.078 ± 0.022	3.699ProGlu: 3.699 ± 0.027	2.13ProPhe: 2.13 ± 0.019	3.798ProGly: 3.798 ± 0.027	1.462ProHis: 1.462 ± 0.014	2.679ProIle: 2.679 ± 0.02	2.8ProLys: 2.8 ± 0.024	4.94ProLeu: 4.94 ± 0.03	1.065ProMet: 1.065 ± 0.013	2.214ProAsn: 2.214 ± 0.021	5.537ProPro: 5.537 ± 0.066	2.489ProGln: 2.489 ± 0.025	3.611ProArg: 3.611 ± 0.03	6.034ProSer: 6.034 ± 0.044	4.294ProThr: 4.294 ± 0.032	3.331ProVal: 3.331 ± 0.027	0.783ProTrp: 0.783 ± 0.011	1.557ProTyr: 1.557 ± 0.016	0.0ProXaa: 0.0 ± 0.0
Gln	3.289GlnAla: 3.289 ± 0.024	0.455GlnCys: 0.455 ± 0.01	1.985GlnAsp: 1.985 ± 0.016	2.312GlnGlu: 2.312 ± 0.02	1.226GlnPhe: 1.226 ± 0.015	2.279GlnGly: 2.279 ± 0.02	1.115GlnHis: 1.115 ± 0.014	1.831GlnIle: 1.831 ± 0.016	1.954GlnLys: 1.954 ± 0.018	3.332GlnLeu: 3.332 ± 0.024	0.802GlnMet: 0.802 ± 0.013	1.511GlnAsn: 1.511 ± 0.015	2.428GlnPro: 2.428 ± 0.021	2.076GlnGln: 2.076 ± 0.036	2.607GlnArg: 2.607 ± 0.02	2.93GlnSer: 2.93 ± 0.023	2.252GlnThr: 2.252 ± 0.021	2.024GlnVal: 2.024 ± 0.018	0.576GlnTrp: 0.576 ± 0.01	1.143GlnTyr: 1.143 ± 0.015	0.0GlnXaa: 0.0 ± 0.0
Arg	4.95ArgAla: 4.95 ± 0.029	0.828ArgCys: 0.828 ± 0.013	3.281ArgAsp: 3.281 ± 0.027	3.931ArgGlu: 3.931 ± 0.033	2.144ArgPhe: 2.144 ± 0.019	3.874ArgGly: 3.874 ± 0.033	1.625ArgHis: 1.625 ± 0.015	2.969ArgIle: 2.969 ± 0.021	3.609ArgLys: 3.609 ± 0.024	5.669ArgLeu: 5.669 ± 0.032	1.364ArgMet: 1.364 ± 0.015	2.309ArgAsn: 2.309 ± 0.021	3.658ArgPro: 3.658 ± 0.026	2.495ArgGln: 2.495 ± 0.023	5.313ArgArg: 5.313 ± 0.032	4.781ArgSer: 4.781 ± 0.031	3.421ArgThr: 3.421 ± 0.022	3.463ArgVal: 3.463 ± 0.025	1.013ArgTrp: 1.013 ± 0.011	1.657ArgTyr: 1.657 ± 0.015	0.0ArgXaa: 0.0 ± 0.0
Ser	6.692SerAla: 6.692 ± 0.041	0.961SerCys: 0.961 ± 0.014	4.01SerAsp: 4.01 ± 0.03	4.002SerGlu: 4.002 ± 0.027	3.047SerPhe: 3.047 ± 0.024	5.291SerGly: 5.291 ± 0.034	1.964SerHis: 1.964 ± 0.019	4.02SerIle: 4.02 ± 0.026	3.8SerLys: 3.8 ± 0.03	7.158SerLeu: 7.158 ± 0.042	1.653SerMet: 1.653 ± 0.017	3.031SerAsn: 3.031 ± 0.023	5.607SerPro: 5.607 ± 0.045	3.068SerGln: 3.068 ± 0.025	4.959SerArg: 4.959 ± 0.036	8.614SerSer: 8.614 ± 0.075	5.768SerThr: 5.768 ± 0.045	4.451SerVal: 4.451 ± 0.027	1.152SerTrp: 1.152 ± 0.014	2.072SerTyr: 2.072 ± 0.019	0.0SerXaa: 0.0 ± 0.0
Thr	5.368ThrAla: 5.368 ± 0.03	0.813ThrCys: 0.813 ± 0.013	2.756ThrAsp: 2.756 ± 0.021	3.044ThrGlu: 3.044 ± 0.024	2.333ThrPhe: 2.333 ± 0.022	3.982ThrGly: 3.982 ± 0.031	1.381ThrHis: 1.381 ± 0.014	3.133ThrIle: 3.133 ± 0.024	2.69ThrLys: 2.69 ± 0.022	5.447ThrLeu: 5.447 ± 0.028	1.17ThrMet: 1.17 ± 0.014	2.091ThrAsn: 2.091 ± 0.018	4.564ThrPro: 4.564 ± 0.038	2.058ThrGln: 2.058 ± 0.017	3.203ThrArg: 3.203 ± 0.022	5.374ThrSer: 5.374 ± 0.035	4.427ThrThr: 4.427 ± 0.036	3.63ThrVal: 3.63 ± 0.022	0.895ThrTrp: 0.895 ± 0.012	1.631ThrTyr: 1.631 ± 0.015	0.0ThrXaa: 0.0 ± 0.0
Val	5.267ValAla: 5.267 ± 0.036	0.864ValCys: 0.864 ± 0.011	3.565ValAsp: 3.565 ± 0.024	4.095ValGlu: 4.095 ± 0.031	2.455ValPhe: 2.455 ± 0.021	4.077ValGly: 4.077 ± 0.03	1.378ValHis: 1.378 ± 0.015	2.822ValIle: 2.822 ± 0.026	2.976ValLys: 2.976 ± 0.022	5.637ValLeu: 5.637 ± 0.031	1.297ValMet: 1.297 ± 0.015	2.088ValAsn: 2.088 ± 0.018	3.508ValPro: 3.508 ± 0.026	2.259ValGln: 2.259 ± 0.019	3.501ValArg: 3.501 ± 0.022	4.404ValSer: 4.404 ± 0.024	3.286ValThr: 3.286 ± 0.026	4.364ValVal: 4.364 ± 0.032	0.93ValTrp: 0.93 ± 0.012	1.714ValTyr: 1.714 ± 0.016	0.0ValXaa: 0.0 ± 0.0
Trp	1.212TrpAla: 1.212 ± 0.015	0.228TrpCys: 0.228 ± 0.005	0.93TrpAsp: 0.93 ± 0.012	0.932TrpGlu: 0.932 ± 0.014	0.559TrpPhe: 0.559 ± 0.008	1.0TrpGly: 1.0 ± 0.013	0.383TrpHis: 0.383 ± 0.008	0.819TrpIle: 0.819 ± 0.012	0.884TrpLys: 0.884 ± 0.012	1.387TrpLeu: 1.387 ± 0.015	0.394TrpMet: 0.394 ± 0.009	0.639TrpAsn: 0.639 ± 0.009	0.674TrpPro: 0.674 ± 0.012	0.558TrpGln: 0.558 ± 0.01	1.055TrpArg: 1.055 ± 0.014	1.07TrpSer: 1.07 ± 0.014	0.936TrpThr: 0.936 ± 0.013	0.963TrpVal: 0.963 ± 0.013	0.289TrpTrp: 0.289 ± 0.007	0.45TrpTyr: 0.45 ± 0.007	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.209TyrAla: 2.209 ± 0.02	0.442TyrCys: 0.442 ± 0.008	1.616TyrAsp: 1.616 ± 0.018	1.568TyrGlu: 1.568 ± 0.016	1.166TyrPhe: 1.166 ± 0.014	2.075TyrGly: 2.075 ± 0.021	0.755TyrHis: 0.755 ± 0.011	1.409TyrIle: 1.409 ± 0.014	1.15TyrLys: 1.15 ± 0.013	2.641TyrLeu: 2.641 ± 0.022	0.58TyrMet: 0.58 ± 0.009	1.106TyrAsn: 1.106 ± 0.013	1.493TyrPro: 1.493 ± 0.017	1.091TyrGln: 1.091 ± 0.014	1.618TyrArg: 1.618 ± 0.017	2.075TyrSer: 2.075 ± 0.017	1.648TyrThr: 1.648 ± 0.016	1.592TyrVal: 1.592 ± 0.017	0.435TyrTrp: 0.435 ± 0.01	0.938TyrTyr: 0.938 ± 0.013	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.015XaaXaa: 0.015 ± 0.007

Statistics based on 16739 proteins (6754280 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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