Amino acid dipepetide frequency for Aythya fuligula (Tufted duck) (Anas fuligula)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.389AlaAla: 7.389 ± 0.044
1.269AlaCys: 1.269 ± 0.011
3.142AlaAsp: 3.142 ± 0.015
5.277AlaGlu: 5.277 ± 0.027
2.413AlaPhe: 2.413 ± 0.015
4.543AlaGly: 4.543 ± 0.025
1.359AlaHis: 1.359 ± 0.009
2.829AlaIle: 2.829 ± 0.015
3.725AlaLys: 3.725 ± 0.02
6.623AlaLeu: 6.623 ± 0.029
1.512AlaMet: 1.512 ± 0.01
2.254AlaAsn: 2.254 ± 0.012
3.647AlaPro: 3.647 ± 0.027
3.109AlaGln: 3.109 ± 0.02
3.393AlaArg: 3.393 ± 0.018
5.743AlaSer: 5.743 ± 0.028
3.501AlaThr: 3.501 ± 0.02
4.948AlaVal: 4.948 ± 0.022
0.685AlaTrp: 0.685 ± 0.008
1.523AlaTyr: 1.523 ± 0.011
0.002AlaXaa: 0.002 ± 0.0
Cys
1.143CysAla: 1.143 ± 0.011
0.558CysCys: 0.558 ± 0.009
1.015CysAsp: 1.015 ± 0.013
1.282CysGlu: 1.282 ± 0.014
0.788CysPhe: 0.788 ± 0.008
1.37CysGly: 1.37 ± 0.015
0.597CysHis: 0.597 ± 0.007
1.008CysIle: 1.008 ± 0.01
1.187CysLys: 1.187 ± 0.011
1.944CysLeu: 1.944 ± 0.014
0.42CysMet: 0.42 ± 0.005
0.829CysAsn: 0.829 ± 0.009
1.159CysPro: 1.159 ± 0.015
0.985CysGln: 0.985 ± 0.011
1.182CysArg: 1.182 ± 0.012
1.925CysSer: 1.925 ± 0.017
1.082CysThr: 1.082 ± 0.012
1.203CysVal: 1.203 ± 0.012
0.242CysTrp: 0.242 ± 0.004
0.579CysTyr: 0.579 ± 0.006
0.001CysXaa: 0.001 ± 0.0
Asp
3.034AspAla: 3.034 ± 0.014
1.043AspCys: 1.043 ± 0.011
2.959AspAsp: 2.959 ± 0.018
3.851AspGlu: 3.851 ± 0.02
2.13AspPhe: 2.13 ± 0.012
3.47AspGly: 3.47 ± 0.02
1.145AspHis: 1.145 ± 0.008
2.768AspIle: 2.768 ± 0.015
2.822AspLys: 2.822 ± 0.018
4.919AspLeu: 4.919 ± 0.019
1.152AspMet: 1.152 ± 0.009
1.869AspAsn: 1.869 ± 0.013
2.739AspPro: 2.739 ± 0.016
1.897AspGln: 1.897 ± 0.012
2.448AspArg: 2.448 ± 0.014
4.429AspSer: 4.429 ± 0.025
2.629AspThr: 2.629 ± 0.015
3.187AspVal: 3.187 ± 0.018
0.575AspTrp: 0.575 ± 0.006
1.591AspTyr: 1.591 ± 0.011
0.002AspXaa: 0.002 ± 0.0
Glu
5.102GluAla: 5.102 ± 0.026
1.23GluCys: 1.23 ± 0.017
4.699GluAsp: 4.699 ± 0.022
8.658GluGlu: 8.658 ± 0.052
2.041GluPhe: 2.041 ± 0.012
4.125GluGly: 4.125 ± 0.023
1.601GluHis: 1.601 ± 0.012
3.474GluIle: 3.474 ± 0.017
5.88GluLys: 5.88 ± 0.042
6.638GluLeu: 6.638 ± 0.038
1.847GluMet: 1.847 ± 0.014
3.411GluAsn: 3.411 ± 0.018
3.057GluPro: 3.057 ± 0.023
3.498GluGln: 3.498 ± 0.024
4.264GluArg: 4.264 ± 0.025
4.856GluSer: 4.856 ± 0.025
3.713GluThr: 3.713 ± 0.019
4.279GluVal: 4.279 ± 0.02
0.678GluTrp: 0.678 ± 0.006
1.747GluTyr: 1.747 ± 0.013
0.003GluXaa: 0.003 ± 0.0
Phe
1.997PheAla: 1.997 ± 0.014
0.847PheCys: 0.847 ± 0.008
1.699PheAsp: 1.699 ± 0.01
2.012PheGlu: 2.012 ± 0.011
1.478PhePhe: 1.478 ± 0.013
2.105PheGly: 2.105 ± 0.015
0.972PheHis: 0.972 ± 0.008
1.811PheIle: 1.811 ± 0.013
1.782PheLys: 1.782 ± 0.013
3.599PheLeu: 3.599 ± 0.02
0.748PheMet: 0.748 ± 0.007
1.368PheAsn: 1.368 ± 0.011
1.857PhePro: 1.857 ± 0.012
1.708PheGln: 1.708 ± 0.012
1.779PheArg: 1.779 ± 0.014
3.162PheSer: 3.162 ± 0.017
1.959PheThr: 1.959 ± 0.014
2.141PheVal: 2.141 ± 0.014
0.442PheTrp: 0.442 ± 0.006
1.124PheTyr: 1.124 ± 0.01
0.001PheXaa: 0.001 ± 0.0
Gly
4.107GlyAla: 4.107 ± 0.026
1.193GlyCys: 1.193 ± 0.013
3.155GlyAsp: 3.155 ± 0.018
3.995GlyGlu: 3.995 ± 0.025
2.316GlyPhe: 2.316 ± 0.016
4.761GlyGly: 4.761 ± 0.04
1.509GlyHis: 1.509 ± 0.011
2.753GlyIle: 2.753 ± 0.016
3.765GlyLys: 3.765 ± 0.02
5.165GlyLeu: 5.165 ± 0.029
1.368GlyMet: 1.368 ± 0.012
2.537GlyAsn: 2.537 ± 0.015
3.305GlyPro: 3.305 ± 0.039
2.689GlyGln: 2.689 ± 0.017
3.523GlyArg: 3.523 ± 0.02
5.77GlySer: 5.77 ± 0.029
3.575GlyThr: 3.575 ± 0.021
3.388GlyVal: 3.388 ± 0.02
0.747GlyTrp: 0.747 ± 0.009
1.792GlyTyr: 1.792 ± 0.015
0.003GlyXaa: 0.003 ± 0.0
His
1.357HisAla: 1.357 ± 0.01
0.666HisCys: 0.666 ± 0.008
0.95HisAsp: 0.95 ± 0.009
1.393HisGlu: 1.393 ± 0.01
0.986HisPhe: 0.986 ± 0.009
1.51HisGly: 1.51 ± 0.012
0.907HisHis: 0.907 ± 0.012
1.253HisIle: 1.253 ± 0.01
1.332HisLys: 1.332 ± 0.011
2.637HisLeu: 2.637 ± 0.016
0.557HisMet: 0.557 ± 0.005
0.935HisAsn: 0.935 ± 0.008
1.499HisPro: 1.499 ± 0.011
1.184HisGln: 1.184 ± 0.011
1.462HisArg: 1.462 ± 0.011
2.244HisSer: 2.244 ± 0.014
1.299HisThr: 1.299 ± 0.01
1.481HisVal: 1.481 ± 0.009
0.285HisTrp: 0.285 ± 0.004
0.835HisTyr: 0.835 ± 0.007
0.001HisXaa: 0.001 ± 0.0
Ile
2.835IleAla: 2.835 ± 0.014
1.04IleCys: 1.04 ± 0.009
2.216IleAsp: 2.216 ± 0.013
2.827IleGlu: 2.827 ± 0.017
1.795IlePhe: 1.795 ± 0.014
2.28IleGly: 2.28 ± 0.014
1.239IleHis: 1.239 ± 0.008
2.423IleIle: 2.423 ± 0.017
2.849IleLys: 2.849 ± 0.017
4.388IleLeu: 4.388 ± 0.019
0.989IleMet: 0.989 ± 0.008
2.031IleAsn: 2.031 ± 0.013
2.689IlePro: 2.689 ± 0.015
2.418IleGln: 2.418 ± 0.013
2.4IleArg: 2.4 ± 0.013
3.92IleSer: 3.92 ± 0.017
2.746IleThr: 2.746 ± 0.017
2.61IleVal: 2.61 ± 0.017
0.483IleTrp: 0.483 ± 0.007
1.387IleTyr: 1.387 ± 0.011
0.001IleXaa: 0.001 ± 0.0
Lys
4.059LysAla: 4.059 ± 0.022
1.114LysCys: 1.114 ± 0.01
3.468LysAsp: 3.468 ± 0.021
5.701LysGlu: 5.701 ± 0.037
1.704LysPhe: 1.704 ± 0.01
3.34LysGly: 3.34 ± 0.025
1.508LysHis: 1.508 ± 0.011
2.927LysIle: 2.927 ± 0.017
5.222LysLys: 5.222 ± 0.031
5.469LysLeu: 5.469 ± 0.024
1.536LysMet: 1.536 ± 0.011
2.64LysAsn: 2.64 ± 0.014
3.197LysPro: 3.197 ± 0.022
3.058LysGln: 3.058 ± 0.021
3.529LysArg: 3.529 ± 0.02
4.36LysSer: 4.36 ± 0.024
3.385LysThr: 3.385 ± 0.016
3.614LysVal: 3.614 ± 0.02
0.613LysTrp: 0.613 ± 0.007
1.689LysTyr: 1.689 ± 0.013
0.003LysXaa: 0.003 ± 0.001
Leu
6.287LeuAla: 6.287 ± 0.029
1.976LeuCys: 1.976 ± 0.014
4.685LeuAsp: 4.685 ± 0.017
7.217LeuGlu: 7.217 ± 0.04
3.052LeuPhe: 3.052 ± 0.023
5.079LeuGly: 5.079 ± 0.024
2.635LeuHis: 2.635 ± 0.014
3.743LeuIle: 3.743 ± 0.02
6.115LeuLys: 6.115 ± 0.028
9.833LeuLeu: 9.833 ± 0.048
1.926LeuMet: 1.926 ± 0.012
3.694LeuAsn: 3.694 ± 0.017
5.607LeuPro: 5.607 ± 0.026
5.764LeuGln: 5.764 ± 0.034
5.442LeuArg: 5.442 ± 0.025
7.748LeuSer: 7.748 ± 0.029
4.736LeuThr: 4.736 ± 0.019
4.989LeuVal: 4.989 ± 0.024
0.971LeuTrp: 0.971 ± 0.009
2.51LeuTyr: 2.51 ± 0.015
0.003LeuXaa: 0.003 ± 0.001
Met
1.813MetAla: 1.813 ± 0.012
0.385MetCys: 0.385 ± 0.005
1.275MetAsp: 1.275 ± 0.008
1.976MetGlu: 1.976 ± 0.014
0.739MetPhe: 0.739 ± 0.007
1.27MetGly: 1.27 ± 0.012
0.492MetHis: 0.492 ± 0.006
0.859MetIle: 0.859 ± 0.008
1.574MetLys: 1.574 ± 0.012
1.962MetLeu: 1.962 ± 0.012
0.6MetMet: 0.6 ± 0.007
0.957MetAsn: 0.957 ± 0.009
1.122MetPro: 1.122 ± 0.009
1.076MetGln: 1.076 ± 0.01
1.077MetArg: 1.077 ± 0.008
1.641MetSer: 1.641 ± 0.01
1.106MetThr: 1.106 ± 0.008
1.365MetVal: 1.365 ± 0.009
0.241MetTrp: 0.241 ± 0.004
0.595MetTyr: 0.595 ± 0.006
0.0MetXaa: 0.0 ± 0.0
Asn
2.38AsnAla: 2.38 ± 0.012
0.858AsnCys: 0.858 ± 0.01
1.691AsnAsp: 1.691 ± 0.011
2.533AsnGlu: 2.533 ± 0.014
1.454AsnPhe: 1.454 ± 0.011
2.798AsnGly: 2.798 ± 0.02
0.973AsnHis: 0.973 ± 0.008
2.281AsnIle: 2.281 ± 0.015
2.498AsnLys: 2.498 ± 0.015
3.817AsnLeu: 3.817 ± 0.02
0.986AsnMet: 0.986 ± 0.008
1.772AsnAsn: 1.772 ± 0.013
2.187AsnPro: 2.187 ± 0.016
1.79AsnGln: 1.79 ± 0.012
1.957AsnArg: 1.957 ± 0.011
3.483AsnSer: 3.483 ± 0.02
2.205AsnThr: 2.205 ± 0.013
2.397AsnVal: 2.397 ± 0.014
0.434AsnTrp: 0.434 ± 0.005
1.185AsnTyr: 1.185 ± 0.01
0.002AsnXaa: 0.002 ± 0.0
Pro
4.731ProAla: 4.731 ± 0.027
1.02ProCys: 1.02 ± 0.014
2.717ProAsp: 2.717 ± 0.015
4.13ProGlu: 4.13 ± 0.022
1.782ProPhe: 1.782 ± 0.012
4.554ProGly: 4.554 ± 0.059
1.34ProHis: 1.34 ± 0.012
1.942ProIle: 1.942 ± 0.015
2.871ProLys: 2.871 ± 0.022
4.798ProLeu: 4.798 ± 0.02
0.994ProMet: 0.994 ± 0.009
1.899ProAsn: 1.899 ± 0.014
5.643ProPro: 5.643 ± 0.057
2.711ProGln: 2.711 ± 0.021
2.916ProArg: 2.916 ± 0.017
5.497ProSer: 5.497 ± 0.032
2.947ProThr: 2.947 ± 0.021
3.879ProVal: 3.879 ± 0.022
0.532ProTrp: 0.532 ± 0.007
1.441ProTyr: 1.441 ± 0.013
0.002ProXaa: 0.002 ± 0.0
Gln
3.307GlnAla: 3.307 ± 0.017
0.918GlnCys: 0.918 ± 0.011
2.321GlnAsp: 2.321 ± 0.013
3.956GlnGlu: 3.956 ± 0.029
1.42GlnPhe: 1.42 ± 0.009
2.671GlnGly: 2.671 ± 0.018
1.374GlnHis: 1.374 ± 0.012
2.137GlnIle: 2.137 ± 0.012
3.194GlnLys: 3.194 ± 0.021
4.697GlnLeu: 4.697 ± 0.028
1.176GlnMet: 1.176 ± 0.009
2.064GlnAsn: 2.064 ± 0.013
2.809GlnPro: 2.809 ± 0.022
3.586GlnGln: 3.586 ± 0.035
2.855GlnArg: 2.855 ± 0.017
3.454GlnSer: 3.454 ± 0.023
2.502GlnThr: 2.502 ± 0.016
2.721GlnVal: 2.721 ± 0.014
0.517GlnTrp: 0.517 ± 0.006
1.291GlnTyr: 1.291 ± 0.01
0.001GlnXaa: 0.001 ± 0.0
Arg
3.507ArgAla: 3.507 ± 0.019
1.125ArgCys: 1.125 ± 0.014
2.744ArgAsp: 2.744 ± 0.015
3.997ArgGlu: 3.997 ± 0.021
1.757ArgPhe: 1.757 ± 0.012
3.28ArgGly: 3.28 ± 0.021
1.43ArgHis: 1.43 ± 0.01
2.475ArgIle: 2.475 ± 0.012
3.738ArgLys: 3.738 ± 0.019
5.048ArgLeu: 5.048 ± 0.023
1.213ArgMet: 1.213 ± 0.009
2.23ArgAsn: 2.23 ± 0.013
2.797ArgPro: 2.797 ± 0.017
2.686ArgGln: 2.686 ± 0.018
4.279ArgArg: 4.279 ± 0.027
4.469ArgSer: 4.469 ± 0.027
2.825ArgThr: 2.825 ± 0.017
2.942ArgVal: 2.942 ± 0.017
0.613ArgTrp: 0.613 ± 0.007
1.51ArgTyr: 1.51 ± 0.011
0.002ArgXaa: 0.002 ± 0.0
Ser
5.596SerAla: 5.596 ± 0.023
1.752SerCys: 1.752 ± 0.013
4.203SerAsp: 4.203 ± 0.023
5.527SerGlu: 5.527 ± 0.027
2.921SerPhe: 2.921 ± 0.015
5.353SerGly: 5.353 ± 0.024
2.019SerHis: 2.019 ± 0.014
3.502SerIle: 3.502 ± 0.017
4.553SerLys: 4.553 ± 0.024
7.904SerLeu: 7.904 ± 0.031
1.711SerMet: 1.711 ± 0.011
3.093SerAsn: 3.093 ± 0.018
6.097SerPro: 6.097 ± 0.036
3.942SerGln: 3.942 ± 0.021
4.474SerArg: 4.474 ± 0.024
10.246SerSer: 10.246 ± 0.064
4.977SerThr: 4.977 ± 0.036
5.069SerVal: 5.069 ± 0.023
0.936SerTrp: 0.936 ± 0.009
2.156SerTyr: 2.156 ± 0.014
0.002SerXaa: 0.002 ± 0.0
Thr
4.016ThrAla: 4.016 ± 0.023
1.22ThrCys: 1.22 ± 0.015
2.737ThrAsp: 2.737 ± 0.014
3.957ThrGlu: 3.957 ± 0.019
1.953ThrPhe: 1.953 ± 0.012
3.414ThrGly: 3.414 ± 0.02
1.16ThrHis: 1.16 ± 0.009
2.443ThrIle: 2.443 ± 0.016
2.936ThrLys: 2.936 ± 0.017
4.991ThrLeu: 4.991 ± 0.018
1.137ThrMet: 1.137 ± 0.009
1.921ThrAsn: 1.921 ± 0.012
3.565ThrPro: 3.565 ± 0.026
2.235ThrGln: 2.235 ± 0.013
2.421ThrArg: 2.421 ± 0.013
4.976ThrSer: 4.976 ± 0.033
3.263ThrThr: 3.263 ± 0.038
3.956ThrVal: 3.956 ± 0.023
0.637ThrTrp: 0.637 ± 0.007
1.442ThrTyr: 1.442 ± 0.01
0.002ThrXaa: 0.002 ± 0.0
Val
4.115ValAla: 4.115 ± 0.02
1.382ValCys: 1.382 ± 0.013
2.976ValAsp: 2.976 ± 0.015
3.997ValGlu: 3.997 ± 0.021
2.302ValPhe: 2.302 ± 0.015
3.157ValGly: 3.157 ± 0.017
1.486ValHis: 1.486 ± 0.01
2.937ValIle: 2.937 ± 0.017
3.74ValLys: 3.74 ± 0.021
5.915ValLeu: 5.915 ± 0.027
1.327ValMet: 1.327 ± 0.01
2.474ValAsn: 2.474 ± 0.014
3.678ValPro: 3.678 ± 0.023
2.849ValGln: 2.849 ± 0.015
2.969ValArg: 2.969 ± 0.016
4.934ValSer: 4.934 ± 0.024
3.817ValThr: 3.817 ± 0.027
3.994ValVal: 3.994 ± 0.022
0.648ValTrp: 0.648 ± 0.008
1.612ValTyr: 1.612 ± 0.012
0.001ValXaa: 0.001 ± 0.0
Trp
0.63TrpAla: 0.63 ± 0.007
0.221TrpCys: 0.221 ± 0.004
0.613TrpAsp: 0.613 ± 0.007
0.749TrpGlu: 0.749 ± 0.008
0.399TrpPhe: 0.399 ± 0.005
0.61TrpGly: 0.61 ± 0.011
0.287TrpHis: 0.287 ± 0.004
0.531TrpIle: 0.531 ± 0.007
0.764TrpLys: 0.764 ± 0.008
1.094TrpLeu: 1.094 ± 0.009
0.305TrpMet: 0.305 ± 0.005
0.513TrpAsn: 0.513 ± 0.006
0.429TrpPro: 0.429 ± 0.006
0.513TrpGln: 0.513 ± 0.005
0.646TrpArg: 0.646 ± 0.006
0.813TrpSer: 0.813 ± 0.01
0.596TrpThr: 0.596 ± 0.007
0.586TrpVal: 0.586 ± 0.006
0.168TrpTrp: 0.168 ± 0.003
0.333TrpTyr: 0.333 ± 0.005
0.001TrpXaa: 0.001 ± 0.0
Tyr
1.477TyrAla: 1.477 ± 0.011
0.68TyrCys: 0.68 ± 0.007
1.39TyrAsp: 1.39 ± 0.011
1.763TyrGlu: 1.763 ± 0.012
1.159TyrPhe: 1.159 ± 0.01
1.726TyrGly: 1.726 ± 0.013
0.741TyrHis: 0.741 ± 0.007
1.47TyrIle: 1.47 ± 0.013
1.586TyrLys: 1.586 ± 0.013
2.571TyrLeu: 2.571 ± 0.014
0.62TyrMet: 0.62 ± 0.007
1.189TyrAsn: 1.189 ± 0.01
1.257TyrPro: 1.257 ± 0.01
1.274TyrGln: 1.274 ± 0.009
1.646TyrArg: 1.646 ± 0.013
2.359TyrSer: 2.359 ± 0.015
1.519TyrThr: 1.519 ± 0.012
1.56TyrVal: 1.56 ± 0.012
0.355TyrTrp: 0.355 ± 0.006
0.965TyrTyr: 0.965 ± 0.009
0.001TyrXaa: 0.001 ± 0.0
Xaa
0.002XaaAla: 0.002 ± 0.0
0.002XaaCys: 0.002 ± 0.0
0.001XaaAsp: 0.001 ± 0.0
0.002XaaGlu: 0.002 ± 0.0
0.002XaaPhe: 0.002 ± 0.0
0.003XaaGly: 0.003 ± 0.0
0.001XaaHis: 0.001 ± 0.0
0.001XaaIle: 0.001 ± 0.0
0.003XaaLys: 0.003 ± 0.001
0.003XaaLeu: 0.003 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.002XaaAsn: 0.002 ± 0.0
0.003XaaPro: 0.003 ± 0.0
0.001XaaGln: 0.001 ± 0.0
0.002XaaArg: 0.002 ± 0.0
0.002XaaSer: 0.002 ± 0.0
0.001XaaThr: 0.001 ± 0.0
0.002XaaVal: 0.002 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.001XaaTyr: 0.001 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 24034 proteins (17668086 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski