Amino acid dipepetide frequency for Paxillus involutus ATCC 200175

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.276AlaAla: 7.276 ± 0.056	1.33AlaCys: 1.33 ± 0.019	3.871AlaAsp: 3.871 ± 0.037	4.684AlaGlu: 4.684 ± 0.046	3.123AlaPhe: 3.123 ± 0.032	4.854AlaGly: 4.854 ± 0.043	2.229AlaHis: 2.229 ± 0.024	4.122AlaIle: 4.122 ± 0.04	3.465AlaLys: 3.465 ± 0.039	7.912AlaLeu: 7.912 ± 0.054	1.93AlaMet: 1.93 ± 0.025	2.76AlaAsn: 2.76 ± 0.031	4.609AlaPro: 4.609 ± 0.046	3.192AlaGln: 3.192 ± 0.029	4.939AlaArg: 4.939 ± 0.041	7.115AlaSer: 7.115 ± 0.052	5.063AlaThr: 5.063 ± 0.044	5.278AlaVal: 5.278 ± 0.038	1.228AlaTrp: 1.228 ± 0.019	2.17AlaTyr: 2.17 ± 0.029	0.0AlaXaa: 0.0 ± 0.0
Cys	1.145CysAla: 1.145 ± 0.017	0.316CysCys: 0.316 ± 0.011	0.789CysAsp: 0.789 ± 0.018	0.698CysGlu: 0.698 ± 0.012	0.681CysPhe: 0.681 ± 0.013	1.038CysGly: 1.038 ± 0.02	0.47CysHis: 0.47 ± 0.013	0.836CysIle: 0.836 ± 0.013	0.633CysLys: 0.633 ± 0.013	1.413CysLeu: 1.413 ± 0.022	0.337CysMet: 0.337 ± 0.011	0.523CysAsn: 0.523 ± 0.014	0.981CysPro: 0.981 ± 0.017	0.634CysGln: 0.634 ± 0.014	0.975CysArg: 0.975 ± 0.017	1.175CysSer: 1.175 ± 0.02	0.911CysThr: 0.911 ± 0.018	0.95CysVal: 0.95 ± 0.016	0.316CysTrp: 0.316 ± 0.01	0.41CysTyr: 0.41 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	4.547AspAla: 4.547 ± 0.036	0.663AspCys: 0.663 ± 0.013	4.241AspAsp: 4.241 ± 0.045	4.356AspGlu: 4.356 ± 0.043	2.034AspPhe: 2.034 ± 0.021	4.334AspGly: 4.334 ± 0.042	1.579AspHis: 1.579 ± 0.024	3.17AspIle: 3.17 ± 0.03	2.229AspLys: 2.229 ± 0.031	4.843AspLeu: 4.843 ± 0.042	1.15AspMet: 1.15 ± 0.019	1.864AspAsn: 1.864 ± 0.023	3.421AspPro: 3.421 ± 0.032	1.718AspGln: 1.718 ± 0.021	2.797AspArg: 2.797 ± 0.032	3.841AspSer: 3.841 ± 0.035	3.058AspThr: 3.058 ± 0.03	4.24AspVal: 4.24 ± 0.032	0.895AspTrp: 0.895 ± 0.017	1.362AspTyr: 1.362 ± 0.021	0.0AspXaa: 0.0 ± 0.0
Glu	4.943GluAla: 4.943 ± 0.04	0.791GluCys: 0.791 ± 0.015	4.225GluAsp: 4.225 ± 0.039	5.305GluGlu: 5.305 ± 0.063	1.815GluPhe: 1.815 ± 0.025	4.083GluGly: 4.083 ± 0.044	1.592GluHis: 1.592 ± 0.021	2.594GluIle: 2.594 ± 0.03	2.88GluLys: 2.88 ± 0.038	5.293GluLeu: 5.293 ± 0.039	1.317GluMet: 1.317 ± 0.019	1.925GluAsn: 1.925 ± 0.021	2.678GluPro: 2.678 ± 0.028	2.19GluGln: 2.19 ± 0.026	3.99GluArg: 3.99 ± 0.043	3.853GluSer: 3.853 ± 0.035	3.216GluThr: 3.216 ± 0.031	3.711GluVal: 3.711 ± 0.034	1.048GluTrp: 1.048 ± 0.017	1.525GluTyr: 1.525 ± 0.021	0.0GluXaa: 0.0 ± 0.0
Phe	2.91PheAla: 2.91 ± 0.029	0.664PheCys: 0.664 ± 0.013	2.133PheAsp: 2.133 ± 0.025	1.922PheGlu: 1.922 ± 0.028	1.48PhePhe: 1.48 ± 0.021	2.575PheGly: 2.575 ± 0.03	1.09PheHis: 1.09 ± 0.02	1.888PheIle: 1.888 ± 0.024	1.461PheLys: 1.461 ± 0.02	3.478PheLeu: 3.478 ± 0.034	0.795PheMet: 0.795 ± 0.016	1.38PheAsn: 1.38 ± 0.02	2.062PhePro: 2.062 ± 0.024	1.28PheGln: 1.28 ± 0.021	1.899PheArg: 1.899 ± 0.023	3.1PheSer: 3.1 ± 0.03	2.236PheThr: 2.236 ± 0.023	2.523PheVal: 2.523 ± 0.028	0.682PheTrp: 0.682 ± 0.016	1.01PheTyr: 1.01 ± 0.017	0.0PheXaa: 0.0 ± 0.0
Gly	4.442GlyAla: 4.442 ± 0.044	1.028GlyCys: 1.028 ± 0.018	3.732GlyAsp: 3.732 ± 0.036	3.993GlyGlu: 3.993 ± 0.044	2.349GlyPhe: 2.349 ± 0.031	5.105GlyGly: 5.105 ± 0.054	2.184GlyHis: 2.184 ± 0.033	3.074GlyIle: 3.074 ± 0.032	3.505GlyLys: 3.505 ± 0.037	5.39GlyLeu: 5.39 ± 0.043	1.448GlyMet: 1.448 ± 0.021	2.221GlyAsn: 2.221 ± 0.025	3.267GlyPro: 3.267 ± 0.034	2.287GlyGln: 2.287 ± 0.028	4.091GlyArg: 4.091 ± 0.039	5.44GlySer: 5.44 ± 0.057	4.057GlyThr: 4.057 ± 0.035	4.271GlyVal: 4.271 ± 0.039	1.101GlyTrp: 1.101 ± 0.021	1.731GlyTyr: 1.731 ± 0.024	0.0GlyXaa: 0.0 ± 0.0
His	2.387HisAla: 2.387 ± 0.025	0.49HisCys: 0.49 ± 0.012	1.581HisAsp: 1.581 ± 0.021	1.553HisGlu: 1.553 ± 0.024	1.106HisPhe: 1.106 ± 0.016	1.871HisGly: 1.871 ± 0.025	1.132HisHis: 1.132 ± 0.028	1.571HisIle: 1.571 ± 0.024	1.093HisLys: 1.093 ± 0.019	2.859HisLeu: 2.859 ± 0.03	0.593HisMet: 0.593 ± 0.012	0.972HisAsn: 0.972 ± 0.019	2.189HisPro: 2.189 ± 0.025	1.167HisGln: 1.167 ± 0.02	1.807HisArg: 1.807 ± 0.027	2.332HisSer: 2.332 ± 0.03	1.851HisThr: 1.851 ± 0.028	1.919HisVal: 1.919 ± 0.026	0.444HisTrp: 0.444 ± 0.01	0.729HisTyr: 0.729 ± 0.014	0.0HisXaa: 0.0 ± 0.0
Ile	4.11IleAla: 4.11 ± 0.033	0.828IleCys: 0.828 ± 0.017	2.696IleAsp: 2.696 ± 0.026	2.65IleGlu: 2.65 ± 0.028	1.845IlePhe: 1.845 ± 0.026	2.835IleGly: 2.835 ± 0.033	1.431IleHis: 1.431 ± 0.019	2.526IleIle: 2.526 ± 0.034	2.05IleLys: 2.05 ± 0.023	4.509IleLeu: 4.509 ± 0.043	1.031IleMet: 1.031 ± 0.018	1.697IleAsn: 1.697 ± 0.022	3.414IlePro: 3.414 ± 0.03	1.862IleGln: 1.862 ± 0.027	2.882IleArg: 2.882 ± 0.03	3.92IleSer: 3.92 ± 0.033	2.914IleThr: 2.914 ± 0.03	3.165IleVal: 3.165 ± 0.034	0.894IleTrp: 0.894 ± 0.019	1.295IleTyr: 1.295 ± 0.02	0.0IleXaa: 0.0 ± 0.0
Lys	3.983LysAla: 3.983 ± 0.043	0.599LysCys: 0.599 ± 0.013	2.392LysAsp: 2.392 ± 0.029	2.96LysGlu: 2.96 ± 0.031	1.37LysPhe: 1.37 ± 0.022	3.003LysGly: 3.003 ± 0.036	1.263LysHis: 1.263 ± 0.022	1.954LysIle: 1.954 ± 0.023	2.866LysLys: 2.866 ± 0.035	3.854LysLeu: 3.854 ± 0.037	0.961LysMet: 0.961 ± 0.019	1.447LysAsn: 1.447 ± 0.019	2.384LysPro: 2.384 ± 0.029	1.715LysGln: 1.715 ± 0.023	3.3LysArg: 3.3 ± 0.033	3.077LysSer: 3.077 ± 0.03	2.534LysThr: 2.534 ± 0.032	2.818LysVal: 2.818 ± 0.03	0.684LysTrp: 0.684 ± 0.015	1.173LysTyr: 1.173 ± 0.019	0.0LysXaa: 0.0 ± 0.0
Leu	7.877LeuAla: 7.877 ± 0.049	1.55LeuCys: 1.55 ± 0.023	5.068LeuAsp: 5.068 ± 0.041	5.269LeuGlu: 5.269 ± 0.036	3.449LeuPhe: 3.449 ± 0.032	5.388LeuGly: 5.388 ± 0.041	2.883LeuHis: 2.883 ± 0.033	3.913LeuIle: 3.913 ± 0.035	3.904LeuLys: 3.904 ± 0.034	8.706LeuLeu: 8.706 ± 0.069	1.808LeuMet: 1.808 ± 0.024	3.033LeuAsn: 3.033 ± 0.031	6.231LeuPro: 6.231 ± 0.044	3.937LeuGln: 3.937 ± 0.038	5.948LeuArg: 5.948 ± 0.049	7.78LeuSer: 7.78 ± 0.059	5.43LeuThr: 5.43 ± 0.044	5.842LeuVal: 5.842 ± 0.045	1.356LeuTrp: 1.356 ± 0.021	2.276LeuTyr: 2.276 ± 0.024	0.0LeuXaa: 0.0 ± 0.0
Met	1.859MetAla: 1.859 ± 0.024	0.316MetCys: 0.316 ± 0.009	1.288MetAsp: 1.288 ± 0.02	1.198MetGlu: 1.198 ± 0.019	0.827MetPhe: 0.827 ± 0.015	1.251MetGly: 1.251 ± 0.019	0.633MetHis: 0.633 ± 0.013	0.96MetIle: 0.96 ± 0.016	1.051MetLys: 1.051 ± 0.017	1.978MetLeu: 1.978 ± 0.025	0.491MetMet: 0.491 ± 0.013	0.781MetAsn: 0.781 ± 0.015	1.237MetPro: 1.237 ± 0.018	0.869MetGln: 0.869 ± 0.016	1.197MetArg: 1.197 ± 0.019	1.945MetSer: 1.945 ± 0.025	1.289MetThr: 1.289 ± 0.019	1.352MetVal: 1.352 ± 0.02	0.322MetTrp: 0.322 ± 0.01	0.552MetTyr: 0.552 ± 0.013	0.0MetXaa: 0.0 ± 0.0
Asn	2.957AsnAla: 2.957 ± 0.027	0.459AsnCys: 0.459 ± 0.011	1.931AsnAsp: 1.931 ± 0.024	1.925AsnGlu: 1.925 ± 0.026	1.255AsnPhe: 1.255 ± 0.02	2.611AsnGly: 2.611 ± 0.031	1.029AsnHis: 1.029 ± 0.018	2.007AsnIle: 2.007 ± 0.029	1.367AsnLys: 1.367 ± 0.018	3.177AsnLeu: 3.177 ± 0.031	0.781AsnMet: 0.781 ± 0.013	1.332AsnAsn: 1.332 ± 0.02	2.298AsnPro: 2.298 ± 0.025	1.208AsnGln: 1.208 ± 0.019	1.671AsnArg: 1.671 ± 0.022	2.557AsnSer: 2.557 ± 0.026	2.143AsnThr: 2.143 ± 0.026	2.48AsnVal: 2.48 ± 0.023	0.557AsnTrp: 0.557 ± 0.012	0.856AsnTyr: 0.856 ± 0.017	0.0AsnXaa: 0.0 ± 0.0
Pro	4.977ProAla: 4.977 ± 0.056	0.719ProCys: 0.719 ± 0.016	3.48ProAsp: 3.48 ± 0.032	3.419ProGlu: 3.419 ± 0.034	2.201ProPhe: 2.201 ± 0.027	3.687ProGly: 3.687 ± 0.038	1.828ProHis: 1.828 ± 0.025	2.73ProIle: 2.73 ± 0.028	2.354ProLys: 2.354 ± 0.026	5.475ProLeu: 5.475 ± 0.042	1.153ProMet: 1.153 ± 0.017	2.294ProAsn: 2.294 ± 0.029	6.179ProPro: 6.179 ± 0.081	2.503ProGln: 2.503 ± 0.029	3.525ProArg: 3.525 ± 0.034	7.218ProSer: 7.218 ± 0.073	4.484ProThr: 4.484 ± 0.042	3.686ProVal: 3.686 ± 0.036	0.841ProTrp: 0.841 ± 0.017	1.639ProTyr: 1.639 ± 0.021	0.0ProXaa: 0.0 ± 0.0
Gln	3.176GlnAla: 3.176 ± 0.033	0.591GlnCys: 0.591 ± 0.013	1.943GlnAsp: 1.943 ± 0.022	2.312GlnGlu: 2.312 ± 0.029	1.261GlnPhe: 1.261 ± 0.019	2.343GlnGly: 2.343 ± 0.028	1.258GlnHis: 1.258 ± 0.022	1.707GlnIle: 1.707 ± 0.022	1.689GlnLys: 1.689 ± 0.021	3.627GlnLeu: 3.627 ± 0.038	0.868GlnMet: 0.868 ± 0.017	1.321GlnAsn: 1.321 ± 0.02	2.543GlnPro: 2.543 ± 0.031	1.963GlnGln: 1.963 ± 0.032	2.577GlnArg: 2.577 ± 0.028	3.071GlnSer: 3.071 ± 0.03	2.233GlnThr: 2.233 ± 0.025	2.428GlnVal: 2.428 ± 0.025	0.675GlnTrp: 0.675 ± 0.015	1.03GlnTyr: 1.03 ± 0.018	0.0GlnXaa: 0.0 ± 0.0
Arg	4.83ArgAla: 4.83 ± 0.046	1.008ArgCys: 1.008 ± 0.018	3.289ArgAsp: 3.289 ± 0.035	3.72ArgGlu: 3.72 ± 0.044	2.138ArgPhe: 2.138 ± 0.027	3.646ArgGly: 3.646 ± 0.043	1.792ArgHis: 1.792 ± 0.022	2.956ArgIle: 2.956 ± 0.03	3.18ArgLys: 3.18 ± 0.034	5.532ArgLeu: 5.532 ± 0.045	1.319ArgMet: 1.319 ± 0.021	2.066ArgAsn: 2.066 ± 0.024	3.546ArgPro: 3.546 ± 0.037	2.469ArgGln: 2.469 ± 0.028	4.897ArgArg: 4.897 ± 0.052	4.875ArgSer: 4.875 ± 0.042	3.591ArgThr: 3.591 ± 0.031	3.818ArgVal: 3.818 ± 0.036	1.036ArgTrp: 1.036 ± 0.017	1.588ArgTyr: 1.588 ± 0.02	0.0ArgXaa: 0.0 ± 0.0
Ser	6.46SerAla: 6.46 ± 0.05	1.103SerCys: 1.103 ± 0.016	4.325SerAsp: 4.325 ± 0.035	3.874SerGlu: 3.874 ± 0.034	3.103SerPhe: 3.103 ± 0.03	5.663SerGly: 5.663 ± 0.05	2.353SerHis: 2.353 ± 0.029	4.02SerIle: 4.02 ± 0.04	3.404SerLys: 3.404 ± 0.032	7.681SerLeu: 7.681 ± 0.054	1.733SerMet: 1.733 ± 0.02	2.936SerAsn: 2.936 ± 0.029	6.226SerPro: 6.226 ± 0.071	3.362SerGln: 3.362 ± 0.031	5.151SerArg: 5.151 ± 0.045	8.884SerSer: 8.884 ± 0.081	5.882SerThr: 5.882 ± 0.048	5.048SerVal: 5.048 ± 0.038	1.13SerTrp: 1.13 ± 0.016	1.878SerTyr: 1.878 ± 0.022	0.0SerXaa: 0.0 ± 0.0
Thr	4.994ThrAla: 4.994 ± 0.042	1.006ThrCys: 1.006 ± 0.018	2.815ThrAsp: 2.815 ± 0.031	2.806ThrGlu: 2.806 ± 0.03	2.406ThrPhe: 2.406 ± 0.028	3.91ThrGly: 3.91 ± 0.043	1.747ThrHis: 1.747 ± 0.022	3.233ThrIle: 3.233 ± 0.029	2.557ThrLys: 2.557 ± 0.029	5.765ThrLeu: 5.765 ± 0.044	1.299ThrMet: 1.299 ± 0.02	2.103ThrAsn: 2.103 ± 0.029	4.677ThrPro: 4.677 ± 0.044	2.185ThrGln: 2.185 ± 0.029	3.399ThrArg: 3.399 ± 0.034	5.927ThrSer: 5.927 ± 0.046	4.443ThrThr: 4.443 ± 0.044	3.975ThrVal: 3.975 ± 0.035	0.94ThrTrp: 0.94 ± 0.015	1.615ThrTyr: 1.615 ± 0.023	0.0ThrXaa: 0.0 ± 0.0
Val	5.039ValAla: 5.039 ± 0.039	1.01ValCys: 1.01 ± 0.018	3.842ValAsp: 3.842 ± 0.028	4.129ValGlu: 4.129 ± 0.045	2.515ValPhe: 2.515 ± 0.029	3.9ValGly: 3.9 ± 0.038	1.89ValHis: 1.89 ± 0.023	3.201ValIle: 3.201 ± 0.03	2.829ValLys: 2.829 ± 0.03	6.106ValLeu: 6.106 ± 0.051	1.365ValMet: 1.365 ± 0.02	2.264ValAsn: 2.264 ± 0.024	4.165ValPro: 4.165 ± 0.041	2.506ValGln: 2.506 ± 0.027	3.676ValArg: 3.676 ± 0.034	4.874ValSer: 4.874 ± 0.038	3.903ValThr: 3.903 ± 0.036	4.671ValVal: 4.671 ± 0.04	1.118ValTrp: 1.118 ± 0.02	1.706ValTyr: 1.706 ± 0.021	0.0ValXaa: 0.0 ± 0.0
Trp	1.256TrpAla: 1.256 ± 0.02	0.296TrpCys: 0.296 ± 0.009	1.171TrpAsp: 1.171 ± 0.025	0.92TrpGlu: 0.92 ± 0.015	0.536TrpPhe: 0.536 ± 0.012	0.902TrpGly: 0.902 ± 0.018	0.435TrpHis: 0.435 ± 0.011	0.745TrpIle: 0.745 ± 0.016	0.828TrpLys: 0.828 ± 0.016	1.396TrpLeu: 1.396 ± 0.023	0.451TrpMet: 0.451 ± 0.01	0.723TrpAsn: 0.723 ± 0.014	0.726TrpPro: 0.726 ± 0.015	0.596TrpGln: 0.596 ± 0.013	1.075TrpArg: 1.075 ± 0.018	1.262TrpSer: 1.262 ± 0.02	1.025TrpThr: 1.025 ± 0.018	0.933TrpVal: 0.933 ± 0.018	0.362TrpTrp: 0.362 ± 0.011	0.403TrpTyr: 0.403 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.982TyrAla: 1.982 ± 0.026	0.465TyrCys: 0.465 ± 0.01	1.53TyrAsp: 1.53 ± 0.021	1.282TyrGlu: 1.282 ± 0.019	1.073TyrPhe: 1.073 ± 0.017	1.715TyrGly: 1.715 ± 0.026	0.829TyrHis: 0.829 ± 0.014	1.347TyrIle: 1.347 ± 0.019	0.992TyrLys: 0.992 ± 0.018	2.654TyrLeu: 2.654 ± 0.027	0.567TyrMet: 0.567 ± 0.013	0.958TyrAsn: 0.958 ± 0.02	1.559TyrPro: 1.559 ± 0.023	0.973TyrGln: 0.973 ± 0.018	1.5TyrArg: 1.5 ± 0.022	1.974TyrSer: 1.974 ± 0.026	1.536TyrThr: 1.536 ± 0.023	1.602TyrVal: 1.602 ± 0.02	0.411TyrTrp: 0.411 ± 0.011	0.808TyrTyr: 0.808 ± 0.017	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 11689 proteins (3729177 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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