Amino acid dipepetide frequency for Musa balbisiana (Banana)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.813AlaAla: 9.813 ± 0.112
1.501AlaCys: 1.501 ± 0.012
3.697AlaAsp: 3.697 ± 0.019
4.786AlaGlu: 4.786 ± 0.027
2.912AlaPhe: 2.912 ± 0.018
5.293AlaGly: 5.293 ± 0.029
1.516AlaHis: 1.516 ± 0.012
3.738AlaIle: 3.738 ± 0.021
3.739AlaLys: 3.739 ± 0.021
7.293AlaLeu: 7.293 ± 0.031
1.983AlaMet: 1.983 ± 0.012
2.476AlaAsn: 2.476 ± 0.017
3.734AlaPro: 3.734 ± 0.023
2.199AlaGln: 2.199 ± 0.014
4.428AlaArg: 4.428 ± 0.023
7.252AlaSer: 7.252 ± 0.031
4.268AlaThr: 4.268 ± 0.023
5.855AlaVal: 5.855 ± 0.03
0.876AlaTrp: 0.876 ± 0.009
1.878AlaTyr: 1.878 ± 0.014
0.0AlaXaa: 0.0 ± 0.0
Cys
1.159CysAla: 1.159 ± 0.009
0.593CysCys: 0.593 ± 0.008
0.896CysAsp: 0.896 ± 0.01
0.843CysGlu: 0.843 ± 0.01
0.86CysPhe: 0.86 ± 0.008
1.49CysGly: 1.49 ± 0.013
0.541CysHis: 0.541 ± 0.008
0.92CysIle: 0.92 ± 0.009
0.98CysLys: 0.98 ± 0.011
1.878CysLeu: 1.878 ± 0.014
0.455CysMet: 0.455 ± 0.006
0.75CysAsn: 0.75 ± 0.009
1.024CysPro: 1.024 ± 0.011
0.602CysGln: 0.602 ± 0.008
1.317CysArg: 1.317 ± 0.013
2.02CysSer: 2.02 ± 0.014
0.871CysThr: 0.871 ± 0.009
1.083CysVal: 1.083 ± 0.011
0.26CysTrp: 0.26 ± 0.005
0.536CysTyr: 0.536 ± 0.007
0.0CysXaa: 0.0 ± 0.0
Asp
4.118AspAla: 4.118 ± 0.022
0.927AspCys: 0.927 ± 0.008
3.597AspAsp: 3.597 ± 0.021
3.844AspGlu: 3.844 ± 0.027
2.045AspPhe: 2.045 ± 0.014
4.231AspGly: 4.231 ± 0.023
1.308AspHis: 1.308 ± 0.01
2.652AspIle: 2.652 ± 0.017
2.344AspLys: 2.344 ± 0.015
5.113AspLeu: 5.113 ± 0.028
1.294AspMet: 1.294 ± 0.011
1.758AspAsn: 1.758 ± 0.013
2.874AspPro: 2.874 ± 0.019
1.63AspGln: 1.63 ± 0.013
2.792AspArg: 2.792 ± 0.016
3.983AspSer: 3.983 ± 0.019
2.118AspThr: 2.118 ± 0.016
3.62AspVal: 3.62 ± 0.018
0.691AspTrp: 0.691 ± 0.007
1.38AspTyr: 1.38 ± 0.013
0.0AspXaa: 0.0 ± 0.0
Glu
5.32GluAla: 5.32 ± 0.025
0.855GluCys: 0.855 ± 0.008
3.701GluAsp: 3.701 ± 0.032
6.716GluGlu: 6.716 ± 0.102
2.106GluPhe: 2.106 ± 0.013
3.922GluGly: 3.922 ± 0.02
1.32GluHis: 1.32 ± 0.011
3.262GluIle: 3.262 ± 0.021
4.308GluLys: 4.308 ± 0.041
5.73GluLeu: 5.73 ± 0.029
1.719GluMet: 1.719 ± 0.014
2.452GluAsn: 2.452 ± 0.017
2.257GluPro: 2.257 ± 0.017
2.179GluGln: 2.179 ± 0.016
3.757GluArg: 3.757 ± 0.02
4.27GluSer: 4.27 ± 0.025
2.874GluThr: 2.874 ± 0.019
4.075GluVal: 4.075 ± 0.022
0.711GluTrp: 0.711 ± 0.008
1.466GluTyr: 1.466 ± 0.011
0.0GluXaa: 0.0 ± 0.0
Phe
2.705PheAla: 2.705 ± 0.016
0.86PheCys: 0.86 ± 0.009
2.225PheAsp: 2.225 ± 0.016
2.005PheGlu: 2.005 ± 0.016
1.997PhePhe: 1.997 ± 0.057
2.942PheGly: 2.942 ± 0.017
1.126PheHis: 1.126 ± 0.01
1.721PheIle: 1.721 ± 0.012
1.613PheLys: 1.613 ± 0.013
4.268PheLeu: 4.268 ± 0.022
0.887PheMet: 0.887 ± 0.008
1.337PheAsn: 1.337 ± 0.012
2.106PhePro: 2.106 ± 0.015
1.374PheGln: 1.374 ± 0.01
2.189PheArg: 2.189 ± 0.013
3.779PheSer: 3.779 ± 0.019
1.754PheThr: 1.754 ± 0.013
2.631PheVal: 2.631 ± 0.018
0.527PheTrp: 0.527 ± 0.007
1.125PheTyr: 1.125 ± 0.01
0.0PheXaa: 0.0 ± 0.0
Gly
4.814GlyAla: 4.814 ± 0.023
1.416GlyCys: 1.416 ± 0.014
3.701GlyAsp: 3.701 ± 0.023
3.913GlyGlu: 3.913 ± 0.022
3.069GlyPhe: 3.069 ± 0.015
6.684GlyGly: 6.684 ± 0.049
1.699GlyHis: 1.699 ± 0.013
3.383GlyIle: 3.383 ± 0.021
3.735GlyLys: 3.735 ± 0.018
6.106GlyLeu: 6.106 ± 0.027
1.56GlyMet: 1.56 ± 0.013
2.805GlyAsn: 2.805 ± 0.017
2.757GlyPro: 2.757 ± 0.016
2.095GlyGln: 2.095 ± 0.015
4.689GlyArg: 4.689 ± 0.027
6.425GlySer: 6.425 ± 0.032
3.361GlyThr: 3.361 ± 0.02
4.386GlyVal: 4.386 ± 0.02
1.002GlyTrp: 1.002 ± 0.01
1.981GlyTyr: 1.981 ± 0.014
0.0GlyXaa: 0.0 ± 0.0
His
1.693HisAla: 1.693 ± 0.012
0.537HisCys: 0.537 ± 0.007
1.216HisAsp: 1.216 ± 0.011
1.307HisGlu: 1.307 ± 0.011
0.985HisPhe: 0.985 ± 0.007
1.98HisGly: 1.98 ± 0.014
1.105HisHis: 1.105 ± 0.011
1.128HisIle: 1.128 ± 0.011
1.073HisLys: 1.073 ± 0.012
2.598HisLeu: 2.598 ± 0.017
0.576HisMet: 0.576 ± 0.007
0.845HisAsn: 0.845 ± 0.009
1.596HisPro: 1.596 ± 0.013
1.035HisGln: 1.035 ± 0.01
1.766HisArg: 1.766 ± 0.013
1.971HisSer: 1.971 ± 0.016
0.965HisThr: 0.965 ± 0.01
1.598HisVal: 1.598 ± 0.011
0.311HisTrp: 0.311 ± 0.006
0.672HisTyr: 0.672 ± 0.008
0.0HisXaa: 0.0 ± 0.0
Ile
3.548IleAla: 3.548 ± 0.025
1.03IleCys: 1.03 ± 0.01
2.598IleAsp: 2.598 ± 0.016
2.718IleGlu: 2.718 ± 0.018
1.885IlePhe: 1.885 ± 0.014
3.194IleGly: 3.194 ± 0.017
1.227IleHis: 1.227 ± 0.009
2.365IleIle: 2.365 ± 0.018
2.425IleLys: 2.425 ± 0.016
4.699IleLeu: 4.699 ± 0.024
1.054IleMet: 1.054 ± 0.009
1.775IleAsn: 1.775 ± 0.012
2.71IlePro: 2.71 ± 0.021
1.715IleGln: 1.715 ± 0.011
2.654IleArg: 2.654 ± 0.016
4.441IleSer: 4.441 ± 0.02
2.384IleThr: 2.384 ± 0.015
3.104IleVal: 3.104 ± 0.02
0.617IleTrp: 0.617 ± 0.008
1.349IleTyr: 1.349 ± 0.011
0.0IleXaa: 0.0 ± 0.0
Lys
3.927LysAla: 3.927 ± 0.019
0.812LysCys: 0.812 ± 0.009
2.828LysAsp: 2.828 ± 0.017
4.055LysGlu: 4.055 ± 0.026
1.686LysPhe: 1.686 ± 0.012
3.25LysGly: 3.25 ± 0.017
1.269LysHis: 1.269 ± 0.01
2.6LysIle: 2.6 ± 0.017
4.185LysLys: 4.185 ± 0.065
5.075LysLeu: 5.075 ± 0.027
1.305LysMet: 1.305 ± 0.012
2.119LysAsn: 2.119 ± 0.019
2.553LysPro: 2.553 ± 0.019
2.028LysGln: 2.028 ± 0.015
3.467LysArg: 3.467 ± 0.022
3.995LysSer: 3.995 ± 0.042
2.381LysThr: 2.381 ± 0.014
3.315LysVal: 3.315 ± 0.017
0.668LysTrp: 0.668 ± 0.008
1.343LysTyr: 1.343 ± 0.011
0.0LysXaa: 0.0 ± 0.0
Leu
7.245LeuAla: 7.245 ± 0.032
1.869LeuCys: 1.869 ± 0.014
4.98LeuAsp: 4.98 ± 0.024
5.886LeuGlu: 5.886 ± 0.031
3.812LeuPhe: 3.812 ± 0.023
6.07LeuGly: 6.07 ± 0.027
2.777LeuHis: 2.777 ± 0.017
4.126LeuIle: 4.126 ± 0.022
5.083LeuLys: 5.083 ± 0.025
10.791LeuLeu: 10.791 ± 0.053
2.159LeuMet: 2.159 ± 0.013
3.248LeuAsn: 3.248 ± 0.018
5.835LeuPro: 5.835 ± 0.028
4.196LeuGln: 4.196 ± 0.023
6.324LeuArg: 6.324 ± 0.026
8.611LeuSer: 8.611 ± 0.036
4.202LeuThr: 4.202 ± 0.021
6.456LeuVal: 6.456 ± 0.03
1.174LeuTrp: 1.174 ± 0.009
2.3LeuTyr: 2.3 ± 0.016
0.0LeuXaa: 0.0 ± 0.0
Met
2.414MetAla: 2.414 ± 0.016
0.315MetCys: 0.315 ± 0.006
1.436MetAsp: 1.436 ± 0.01
1.973MetGlu: 1.973 ± 0.014
0.74MetPhe: 0.74 ± 0.008
1.648MetGly: 1.648 ± 0.014
0.556MetHis: 0.556 ± 0.007
1.11MetIle: 1.11 ± 0.01
1.371MetLys: 1.371 ± 0.009
2.146MetLeu: 2.146 ± 0.014
0.668MetMet: 0.668 ± 0.009
0.907MetAsn: 0.907 ± 0.01
1.149MetPro: 1.149 ± 0.012
0.917MetGln: 0.917 ± 0.01
1.32MetArg: 1.32 ± 0.011
1.742MetSer: 1.742 ± 0.013
1.1MetThr: 1.1 ± 0.01
1.652MetVal: 1.652 ± 0.014
0.272MetTrp: 0.272 ± 0.005
0.545MetTyr: 0.545 ± 0.007
0.0MetXaa: 0.0 ± 0.0
Asn
2.491AsnAla: 2.491 ± 0.015
0.751AsnCys: 0.751 ± 0.008
1.749AsnAsp: 1.749 ± 0.015
2.021AsnGlu: 2.021 ± 0.015
1.488AsnPhe: 1.488 ± 0.01
2.733AsnGly: 2.733 ± 0.018
0.974AsnHis: 0.974 ± 0.009
1.984AsnIle: 1.984 ± 0.014
1.876AsnLys: 1.876 ± 0.015
3.876AsnLeu: 3.876 ± 0.022
0.958AsnMet: 0.958 ± 0.01
1.58AsnAsn: 1.58 ± 0.015
2.162AsnPro: 2.162 ± 0.015
1.378AsnGln: 1.378 ± 0.012
1.975AsnArg: 1.975 ± 0.014
3.324AsnSer: 3.324 ± 0.024
1.645AsnThr: 1.645 ± 0.01
2.325AsnVal: 2.325 ± 0.015
0.492AsnTrp: 0.492 ± 0.008
1.088AsnTyr: 1.088 ± 0.011
0.0AsnXaa: 0.0 ± 0.0
Pro
4.224ProAla: 4.224 ± 0.026
0.923ProCys: 0.923 ± 0.01
2.641ProAsp: 2.641 ± 0.016
3.162ProGlu: 3.162 ± 0.019
2.115ProPhe: 2.115 ± 0.014
3.112ProGly: 3.112 ± 0.017
1.251ProHis: 1.251 ± 0.01
2.212ProIle: 2.212 ± 0.015
2.425ProLys: 2.425 ± 0.015
4.867ProLeu: 4.867 ± 0.023
1.045ProMet: 1.045 ± 0.01
1.953ProAsn: 1.953 ± 0.015
5.159ProPro: 5.159 ± 0.055
1.807ProGln: 1.807 ± 0.015
3.208ProArg: 3.208 ± 0.022
5.974ProSer: 5.974 ± 0.029
2.837ProThr: 2.837 ± 0.017
3.423ProVal: 3.423 ± 0.019
0.711ProTrp: 0.711 ± 0.008
1.289ProTyr: 1.289 ± 0.012
0.0ProXaa: 0.0 ± 0.0
Gln
2.545GlnAla: 2.545 ± 0.017
0.571GlnCys: 0.571 ± 0.007
1.536GlnAsp: 1.536 ± 0.013
2.311GlnGlu: 2.311 ± 0.016
1.21GlnPhe: 1.21 ± 0.011
2.044GlnGly: 2.044 ± 0.014
0.971GlnHis: 0.971 ± 0.01
1.783GlnIle: 1.783 ± 0.013
2.056GlnLys: 2.056 ± 0.022
3.511GlnLeu: 3.511 ± 0.019
0.955GlnMet: 0.955 ± 0.01
1.438GlnAsn: 1.438 ± 0.013
1.853GlnPro: 1.853 ± 0.015
2.06GlnGln: 2.06 ± 0.023
2.299GlnArg: 2.299 ± 0.014
2.695GlnSer: 2.695 ± 0.017
1.584GlnThr: 1.584 ± 0.014
2.235GlnVal: 2.235 ± 0.014
0.442GlnTrp: 0.442 ± 0.007
0.83GlnTyr: 0.83 ± 0.009
0.0GlnXaa: 0.0 ± 0.0
Arg
4.257ArgAla: 4.257 ± 0.022
1.273ArgCys: 1.273 ± 0.011
2.868ArgAsp: 2.868 ± 0.018
3.69ArgGlu: 3.69 ± 0.024
2.376ArgPhe: 2.376 ± 0.015
4.016ArgGly: 4.016 ± 0.025
1.577ArgHis: 1.577 ± 0.013
2.908ArgIle: 2.908 ± 0.016
3.759ArgLys: 3.759 ± 0.022
5.823ArgLeu: 5.823 ± 0.025
1.494ArgMet: 1.494 ± 0.012
2.315ArgAsn: 2.315 ± 0.017
3.207ArgPro: 3.207 ± 0.023
2.077ArgGln: 2.077 ± 0.013
5.852ArgArg: 5.852 ± 0.062
5.534ArgSer: 5.534 ± 0.027
2.748ArgThr: 2.748 ± 0.017
3.576ArgVal: 3.576 ± 0.019
1.002ArgTrp: 1.002 ± 0.01
1.515ArgTyr: 1.515 ± 0.012
0.0ArgXaa: 0.0 ± 0.0
Ser
6.486SerAla: 6.486 ± 0.028
1.902SerCys: 1.902 ± 0.014
4.436SerAsp: 4.436 ± 0.022
4.642SerGlu: 4.642 ± 0.042
3.821SerPhe: 3.821 ± 0.019
6.232SerGly: 6.232 ± 0.032
2.111SerHis: 2.111 ± 0.014
4.164SerIle: 4.164 ± 0.024
4.242SerLys: 4.242 ± 0.024
8.816SerLeu: 8.816 ± 0.031
2.107SerMet: 2.107 ± 0.014
3.409SerAsn: 3.409 ± 0.019
5.355SerPro: 5.355 ± 0.03
2.804SerGln: 2.804 ± 0.023
5.133SerArg: 5.133 ± 0.024
12.04SerSer: 12.04 ± 0.101
4.656SerThr: 4.656 ± 0.023
5.27SerVal: 5.27 ± 0.021
1.195SerTrp: 1.195 ± 0.011
2.21SerTyr: 2.21 ± 0.014
0.0SerXaa: 0.0 ± 0.0
Thr
4.005ThrAla: 4.005 ± 0.02
0.95ThrCys: 0.95 ± 0.01
2.295ThrAsp: 2.295 ± 0.015
2.701ThrGlu: 2.701 ± 0.015
1.85ThrPhe: 1.85 ± 0.013
3.455ThrGly: 3.455 ± 0.022
1.023ThrHis: 1.023 ± 0.01
2.41ThrIle: 2.41 ± 0.018
2.343ThrLys: 2.343 ± 0.013
4.338ThrLeu: 4.338 ± 0.021
1.18ThrMet: 1.18 ± 0.01
1.784ThrAsn: 1.784 ± 0.014
2.677ThrPro: 2.677 ± 0.018
1.36ThrGln: 1.36 ± 0.011
2.58ThrArg: 2.58 ± 0.017
4.556ThrSer: 4.556 ± 0.024
2.929ThrThr: 2.929 ± 0.021
3.374ThrVal: 3.374 ± 0.019
0.617ThrTrp: 0.617 ± 0.008
1.269ThrTyr: 1.269 ± 0.011
0.0ThrXaa: 0.0 ± 0.0
Val
5.827ValAla: 5.827 ± 0.029
1.166ValCys: 1.166 ± 0.009
3.804ValAsp: 3.804 ± 0.02
4.258ValGlu: 4.258 ± 0.022
2.575ValPhe: 2.575 ± 0.016
4.475ValGly: 4.475 ± 0.024
1.57ValHis: 1.57 ± 0.011
3.118ValIle: 3.118 ± 0.017
3.244ValLys: 3.244 ± 0.017
6.382ValLeu: 6.382 ± 0.034
1.552ValMet: 1.552 ± 0.011
2.237ValAsn: 2.237 ± 0.016
3.539ValPro: 3.539 ± 0.015
2.132ValGln: 2.132 ± 0.015
3.554ValArg: 3.554 ± 0.023
5.31ValSer: 5.31 ± 0.023
3.22ValThr: 3.22 ± 0.017
5.268ValVal: 5.268 ± 0.05
0.768ValTrp: 0.768 ± 0.008
1.729ValTyr: 1.729 ± 0.011
0.0ValXaa: 0.0 ± 0.0
Trp
0.872TrpAla: 0.872 ± 0.009
0.247TrpCys: 0.247 ± 0.005
0.665TrpAsp: 0.665 ± 0.008
0.747TrpGlu: 0.747 ± 0.009
0.532TrpPhe: 0.532 ± 0.006
0.778TrpGly: 0.778 ± 0.009
0.318TrpHis: 0.318 ± 0.006
0.655TrpIle: 0.655 ± 0.008
0.819TrpLys: 0.819 ± 0.01
1.243TrpLeu: 1.243 ± 0.012
0.354TrpMet: 0.354 ± 0.005
0.631TrpAsn: 0.631 ± 0.008
0.572TrpPro: 0.572 ± 0.008
0.459TrpGln: 0.459 ± 0.007
0.992TrpArg: 0.992 ± 0.01
1.068TrpSer: 1.068 ± 0.01
0.646TrpThr: 0.646 ± 0.007
0.787TrpVal: 0.787 ± 0.009
0.275TrpTrp: 0.275 ± 0.006
0.332TrpTyr: 0.332 ± 0.005
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.772TyrAla: 1.772 ± 0.013
0.579TyrCys: 0.579 ± 0.007
1.449TyrAsp: 1.449 ± 0.01
1.424TyrGlu: 1.424 ± 0.01
1.108TyrPhe: 1.108 ± 0.01
2.034TyrGly: 2.034 ± 0.015
0.719TyrHis: 0.719 ± 0.008
1.253TyrIle: 1.253 ± 0.012
1.24TyrLys: 1.24 ± 0.011
2.594TyrLeu: 2.594 ± 0.015
0.676TyrMet: 0.676 ± 0.007
1.05TyrAsn: 1.05 ± 0.009
1.218TyrPro: 1.218 ± 0.012
0.88TyrGln: 0.88 ± 0.009
1.571TyrArg: 1.571 ± 0.012
2.04TyrSer: 2.04 ± 0.014
1.156TyrThr: 1.156 ± 0.011
1.693TyrVal: 1.693 ± 0.012
0.379TyrTrp: 0.379 ± 0.006
0.885TyrTyr: 0.885 ± 0.009
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 32103 proteins (12394127 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski