Human papillomavirus 135

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Gammapapillomavirus; Gammapapillomavirus 15

Average proteome isoelectric point is 5.98

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 7 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|I3P6K5|I3P6K5_9PAPI Replication protein E1 OS=Human papillomavirus 135 OX=1070408 GN=E1 PE=3 SV=1
MM1 pKa = 7.69KK2 pKa = 9.47GTIATIPDD10 pKa = 3.29VCLEE14 pKa = 3.93EE15 pKa = 5.32LVLPSNLLASEE26 pKa = 4.62EE27 pKa = 4.29SLSPDD32 pKa = 3.85DD33 pKa = 4.51EE34 pKa = 5.28PEE36 pKa = 4.04EE37 pKa = 4.65EE38 pKa = 4.17PTNPYY43 pKa = 10.29RR44 pKa = 11.84VDD46 pKa = 4.0TYY48 pKa = 11.13CGNCQRR54 pKa = 11.84GVRR57 pKa = 11.84LFFVTTASCIRR68 pKa = 11.84TVHH71 pKa = 6.27HH72 pKa = 6.58LLIGEE77 pKa = 4.5LSVICVACSRR87 pKa = 11.84TCFQDD92 pKa = 3.18GRR94 pKa = 11.84PP95 pKa = 3.57

Molecular weight: 10.47 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|I3P6K7|I3P6K7_9PAPI Uncharacterized protein OS=Human papillomavirus 135 OX=1070408 GN=E4 PE=4 SV=1
MM1 pKa = 7.0NQADD5 pKa = 3.92LTDD8 pKa = 4.26RR9 pKa = 11.84FDD11 pKa = 3.65VLQDD15 pKa = 3.38QLLALYY21 pKa = 9.42EE22 pKa = 4.27KK23 pKa = 10.73GATDD27 pKa = 4.03LASQIKK33 pKa = 9.35HH34 pKa = 5.52WEE36 pKa = 3.82LSRR39 pKa = 11.84KK40 pKa = 9.64INVLMYY46 pKa = 8.01YY47 pKa = 9.85SRR49 pKa = 11.84KK50 pKa = 9.64EE51 pKa = 3.66GHH53 pKa = 6.77KK54 pKa = 10.72NLGLQTLPTLQVSEE68 pKa = 4.71YY69 pKa = 9.64NAKK72 pKa = 10.25LAIKK76 pKa = 9.88MMILLKK82 pKa = 10.75SLASSKK88 pKa = 10.51YY89 pKa = 9.91GKK91 pKa = 10.08EE92 pKa = 3.44PWTLTEE98 pKa = 4.12TSADD102 pKa = 3.85LLLTPPKK109 pKa = 9.96NTFKK113 pKa = 10.96KK114 pKa = 10.47GGFQVEE120 pKa = 4.45VYY122 pKa = 10.78YY123 pKa = 11.17DD124 pKa = 4.0NDD126 pKa = 3.67PQNANVYY133 pKa = 6.84TQWEE137 pKa = 4.04FLYY140 pKa = 10.98YY141 pKa = 9.99QDD143 pKa = 6.34LNDD146 pKa = 3.84EE147 pKa = 4.2WHH149 pKa = 6.67KK150 pKa = 11.27VPGDD154 pKa = 3.42VDD156 pKa = 4.42HH157 pKa = 7.16NGLSYY162 pKa = 11.26TDD164 pKa = 3.18ITGEE168 pKa = 3.95KK169 pKa = 9.06IYY171 pKa = 10.55FKK173 pKa = 10.47IFSEE177 pKa = 4.66DD178 pKa = 3.0ADD180 pKa = 4.11RR181 pKa = 11.84YY182 pKa = 10.51SNTGQWTVKK191 pKa = 10.2FKK193 pKa = 10.42STTISSVVTSSKK205 pKa = 10.81KK206 pKa = 10.45SFSAEE211 pKa = 3.83KK212 pKa = 10.5GDD214 pKa = 3.92SQRR217 pKa = 11.84SQHH220 pKa = 6.17RR221 pKa = 11.84EE222 pKa = 3.58SSPEE226 pKa = 3.76EE227 pKa = 4.25GTSSRR232 pKa = 11.84DD233 pKa = 3.14PRR235 pKa = 11.84RR236 pKa = 11.84SKK238 pKa = 10.53RR239 pKa = 11.84YY240 pKa = 8.73SQEE243 pKa = 3.84EE244 pKa = 4.58LPTTTTASPTTSTRR258 pKa = 11.84EE259 pKa = 3.33RR260 pKa = 11.84RR261 pKa = 11.84RR262 pKa = 11.84RR263 pKa = 11.84RR264 pKa = 11.84RR265 pKa = 11.84GSGGEE270 pKa = 3.86QQGEE274 pKa = 4.46STTRR278 pKa = 11.84EE279 pKa = 3.69PRR281 pKa = 11.84AKK283 pKa = 9.47RR284 pKa = 11.84TRR286 pKa = 11.84GPTAPTPDD294 pKa = 3.33QVGSRR299 pKa = 11.84HH300 pKa = 6.07RR301 pKa = 11.84SVPSHH306 pKa = 5.43NLGRR310 pKa = 11.84LGRR313 pKa = 11.84LQADD317 pKa = 3.07AWDD320 pKa = 4.12PPILCVKK327 pKa = 10.62GPANNLKK334 pKa = 10.12CWRR337 pKa = 11.84NRR339 pKa = 11.84FNVKK343 pKa = 9.47FHH345 pKa = 6.83SLFFNVSSVFKK356 pKa = 10.57WLGDD360 pKa = 3.65SNADD364 pKa = 3.57HH365 pKa = 6.97NISRR369 pKa = 11.84MLIAFHH375 pKa = 6.73DD376 pKa = 3.96TYY378 pKa = 11.37EE379 pKa = 4.16RR380 pKa = 11.84ARR382 pKa = 11.84FLQTVTLPRR391 pKa = 11.84GATYY395 pKa = 10.18AYY397 pKa = 10.44GSLDD401 pKa = 3.38SLL403 pKa = 4.41

Molecular weight: 46.03 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

7

0

7

2412

95

601

344.6

38.97

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.39 ± 0.642

1.99 ± 0.778

7.09 ± 0.316

5.556 ± 0.366

4.726 ± 0.387

5.473 ± 0.811

2.114 ± 0.212

5.1 ± 0.676

5.556 ± 0.669

8.955 ± 0.777

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.493 ± 0.372

5.141 ± 0.641

6.343 ± 1.098

4.312 ± 0.398

5.597 ± 0.536

7.338 ± 0.664

6.758 ± 0.882

6.219 ± 0.68

1.161 ± 0.328

3.69 ± 0.368
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski