Amino acid dipepetide frequency for Labrus bergylta (ballan wrasse)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.026AlaAla: 6.026 ± 0.027	1.275AlaCys: 1.275 ± 0.009	3.124AlaAsp: 3.124 ± 0.015	4.468AlaGlu: 4.468 ± 0.022	2.358AlaPhe: 2.358 ± 0.011	4.198AlaGly: 4.198 ± 0.019	1.461AlaHis: 1.461 ± 0.01	2.585AlaIle: 2.585 ± 0.014	3.218AlaLys: 3.218 ± 0.019	6.317AlaLeu: 6.317 ± 0.025	1.553AlaMet: 1.553 ± 0.01	2.119AlaAsn: 2.119 ± 0.01	3.359AlaPro: 3.359 ± 0.021	2.798AlaGln: 2.798 ± 0.015	2.96AlaArg: 2.96 ± 0.014	5.181AlaSer: 5.181 ± 0.021	3.243AlaThr: 3.243 ± 0.017	4.866AlaVal: 4.866 ± 0.019	0.663AlaTrp: 0.663 ± 0.006	1.478AlaTyr: 1.478 ± 0.011	0.0AlaXaa: 0.0 ± 0.0
Cys	1.199CysAla: 1.199 ± 0.01	0.701CysCys: 0.701 ± 0.007	1.155CysAsp: 1.155 ± 0.011	1.284CysGlu: 1.284 ± 0.011	0.96CysPhe: 0.96 ± 0.009	1.56CysGly: 1.56 ± 0.012	0.655CysHis: 0.655 ± 0.007	0.983CysIle: 0.983 ± 0.008	1.185CysLys: 1.185 ± 0.009	2.453CysLeu: 2.453 ± 0.028	0.505CysMet: 0.505 ± 0.006	0.855CysAsn: 0.855 ± 0.008	1.301CysPro: 1.301 ± 0.014	1.016CysGln: 1.016 ± 0.011	1.342CysArg: 1.342 ± 0.011	2.355CysSer: 2.355 ± 0.017	1.201CysThr: 1.201 ± 0.009	1.938CysVal: 1.938 ± 0.035	0.321CysTrp: 0.321 ± 0.005	0.667CysTyr: 0.667 ± 0.006	0.0CysXaa: 0.0 ± 0.0
Asp	2.879AspAla: 2.879 ± 0.013	1.192AspCys: 1.192 ± 0.01	3.103AspAsp: 3.103 ± 0.028	3.692AspGlu: 3.692 ± 0.019	2.183AspPhe: 2.183 ± 0.011	3.581AspGly: 3.581 ± 0.018	1.209AspHis: 1.209 ± 0.009	2.705AspIle: 2.705 ± 0.016	2.739AspLys: 2.739 ± 0.013	4.98AspLeu: 4.98 ± 0.019	1.327AspMet: 1.327 ± 0.009	2.018AspAsn: 2.018 ± 0.012	2.846AspPro: 2.846 ± 0.015	1.976AspGln: 1.976 ± 0.012	2.801AspArg: 2.801 ± 0.023	4.504AspSer: 4.504 ± 0.021	2.688AspThr: 2.688 ± 0.015	3.312AspVal: 3.312 ± 0.018	0.696AspTrp: 0.696 ± 0.006	1.557AspTyr: 1.557 ± 0.011	0.0AspXaa: 0.0 ± 0.0
Glu	4.495GluAla: 4.495 ± 0.024	1.239GluCys: 1.239 ± 0.013	4.397GluAsp: 4.397 ± 0.019	7.79GluGlu: 7.79 ± 0.053	1.927GluPhe: 1.927 ± 0.012	4.143GluGly: 4.143 ± 0.021	1.451GluHis: 1.451 ± 0.011	2.846GluIle: 2.846 ± 0.014	4.657GluLys: 4.657 ± 0.028	6.058GluLeu: 6.058 ± 0.03	1.722GluMet: 1.722 ± 0.009	2.658GluAsn: 2.658 ± 0.013	2.664GluPro: 2.664 ± 0.015	3.014GluGln: 3.014 ± 0.019	4.268GluArg: 4.268 ± 0.025	4.338GluSer: 4.338 ± 0.02	3.463GluThr: 3.463 ± 0.016	4.279GluVal: 4.279 ± 0.016	0.688GluTrp: 0.688 ± 0.007	1.555GluTyr: 1.555 ± 0.01	0.0GluXaa: 0.0 ± 0.0
Phe	1.851PheAla: 1.851 ± 0.011	1.044PheCys: 1.044 ± 0.008	1.821PheAsp: 1.821 ± 0.011	1.879PheGlu: 1.879 ± 0.012	1.756PhePhe: 1.756 ± 0.013	2.194PheGly: 2.194 ± 0.014	1.048PheHis: 1.048 ± 0.009	2.043PheIle: 2.043 ± 0.013	1.918PheLys: 1.918 ± 0.011	4.063PheLeu: 4.063 ± 0.018	0.854PheMet: 0.854 ± 0.006	1.576PheAsn: 1.576 ± 0.01	1.853PhePro: 1.853 ± 0.01	1.62PheGln: 1.62 ± 0.01	1.88PheArg: 1.88 ± 0.013	3.555PheSer: 3.555 ± 0.018	2.457PheThr: 2.457 ± 0.017	2.285PheVal: 2.285 ± 0.012	0.498PheTrp: 0.498 ± 0.005	1.289PheTyr: 1.289 ± 0.009	0.0PheXaa: 0.0 ± 0.0
Gly	3.871GlyAla: 3.871 ± 0.02	1.289GlyCys: 1.289 ± 0.01	3.182GlyAsp: 3.182 ± 0.016	4.083GlyGlu: 4.083 ± 0.019	2.431GlyPhe: 2.431 ± 0.013	5.438GlyGly: 5.438 ± 0.038	1.629GlyHis: 1.629 ± 0.011	2.534GlyIle: 2.534 ± 0.013	3.561GlyLys: 3.561 ± 0.016	5.512GlyLeu: 5.512 ± 0.02	1.467GlyMet: 1.467 ± 0.012	2.455GlyAsn: 2.455 ± 0.013	3.046GlyPro: 3.046 ± 0.032	2.656GlyGln: 2.656 ± 0.016	3.638GlyArg: 3.638 ± 0.017	5.618GlySer: 5.618 ± 0.026	3.351GlyThr: 3.351 ± 0.019	4.055GlyVal: 4.055 ± 0.02	0.768GlyTrp: 0.768 ± 0.007	1.819GlyTyr: 1.819 ± 0.013	0.0GlyXaa: 0.0 ± 0.0
His	1.313HisAla: 1.313 ± 0.009	0.78HisCys: 0.78 ± 0.008	1.013HisAsp: 1.013 ± 0.007	1.185HisGlu: 1.185 ± 0.009	1.101HisPhe: 1.101 ± 0.007	1.51HisGly: 1.51 ± 0.01	1.099HisHis: 1.099 ± 0.014	1.352HisIle: 1.352 ± 0.01	1.314HisLys: 1.314 ± 0.009	2.786HisLeu: 2.786 ± 0.015	0.719HisMet: 0.719 ± 0.007	1.067HisAsn: 1.067 ± 0.009	1.617HisPro: 1.617 ± 0.015	1.282HisGln: 1.282 ± 0.012	1.677HisArg: 1.677 ± 0.013	2.473HisSer: 2.473 ± 0.014	1.981HisThr: 1.981 ± 0.041	1.491HisVal: 1.491 ± 0.009	0.359HisTrp: 0.359 ± 0.004	0.851HisTyr: 0.851 ± 0.007	0.0HisXaa: 0.0 ± 0.0
Ile	2.406IleAla: 2.406 ± 0.013	1.117IleCys: 1.117 ± 0.01	2.11IleAsp: 2.11 ± 0.011	2.367IleGlu: 2.367 ± 0.014	1.867IlePhe: 1.867 ± 0.014	2.311IleGly: 2.311 ± 0.013	1.329IleHis: 1.329 ± 0.012	2.421IleIle: 2.421 ± 0.015	2.571IleLys: 2.571 ± 0.014	4.314IleLeu: 4.314 ± 0.018	1.09IleMet: 1.09 ± 0.008	2.012IleAsn: 2.012 ± 0.012	2.428IlePro: 2.428 ± 0.013	2.218IleGln: 2.218 ± 0.012	2.411IleArg: 2.411 ± 0.012	3.862IleSer: 3.862 ± 0.015	2.804IleThr: 2.804 ± 0.014	2.584IleVal: 2.584 ± 0.014	0.488IleTrp: 0.488 ± 0.006	1.438IleTyr: 1.438 ± 0.015	0.0IleXaa: 0.0 ± 0.0
Lys	3.617LysAla: 3.617 ± 0.018	1.043LysCys: 1.043 ± 0.01	3.243LysAsp: 3.243 ± 0.015	4.664LysGlu: 4.664 ± 0.028	1.642LysPhe: 1.642 ± 0.01	3.19LysGly: 3.19 ± 0.023	1.453LysHis: 1.453 ± 0.009	2.473LysIle: 2.473 ± 0.015	4.558LysLys: 4.558 ± 0.047	5.033LysLeu: 5.033 ± 0.021	1.489LysMet: 1.489 ± 0.009	2.297LysAsn: 2.297 ± 0.013	2.842LysPro: 2.842 ± 0.019	2.541LysGln: 2.541 ± 0.018	3.45LysArg: 3.45 ± 0.017	3.893LysSer: 3.893 ± 0.018	3.319LysThr: 3.319 ± 0.015	3.559LysVal: 3.559 ± 0.015	0.571LysTrp: 0.571 ± 0.005	1.516LysTyr: 1.516 ± 0.011	0.0LysXaa: 0.0 ± 0.0
Leu	5.809LeuAla: 5.809 ± 0.02	2.414LeuCys: 2.414 ± 0.016	4.896LeuAsp: 4.896 ± 0.017	6.215LeuGlu: 6.215 ± 0.03	3.63LeuPhe: 3.63 ± 0.016	5.029LeuGly: 5.029 ± 0.02	2.808LeuHis: 2.808 ± 0.016	3.915LeuIle: 3.915 ± 0.019	5.703LeuLys: 5.703 ± 0.023	10.257LeuLeu: 10.257 ± 0.042	2.183LeuMet: 2.183 ± 0.012	3.754LeuAsn: 3.754 ± 0.016	5.211LeuPro: 5.211 ± 0.023	5.485LeuGln: 5.485 ± 0.027	5.549LeuArg: 5.549 ± 0.022	8.875LeuSer: 8.875 ± 0.041	5.416LeuThr: 5.416 ± 0.023	5.461LeuVal: 5.461 ± 0.023	1.084LeuTrp: 1.084 ± 0.009	2.659LeuTyr: 2.659 ± 0.015	0.0LeuXaa: 0.0 ± 0.0
Met	1.884MetAla: 1.884 ± 0.01	0.529MetCys: 0.529 ± 0.005	1.453MetAsp: 1.453 ± 0.009	1.95MetGlu: 1.95 ± 0.011	0.924MetPhe: 0.924 ± 0.007	1.426MetGly: 1.426 ± 0.01	0.502MetHis: 0.502 ± 0.005	0.926MetIle: 0.926 ± 0.008	1.558MetLys: 1.558 ± 0.009	2.12MetLeu: 2.12 ± 0.012	0.759MetMet: 0.759 ± 0.019	0.975MetAsn: 0.975 ± 0.008	1.055MetPro: 1.055 ± 0.012	0.99MetGln: 0.99 ± 0.008	1.195MetArg: 1.195 ± 0.008	1.934MetSer: 1.934 ± 0.01	1.322MetThr: 1.322 ± 0.008	1.563MetVal: 1.563 ± 0.012	0.269MetTrp: 0.269 ± 0.004	0.655MetTyr: 0.655 ± 0.006	0.0MetXaa: 0.0 ± 0.0
Asn	2.088AsnAla: 2.088 ± 0.012	0.887AsnCys: 0.887 ± 0.008	1.717AsnAsp: 1.717 ± 0.011	2.055AsnGlu: 2.055 ± 0.011	1.453AsnPhe: 1.453 ± 0.009	2.69AsnGly: 2.69 ± 0.013	1.062AsnHis: 1.062 ± 0.008	2.192AsnIle: 2.192 ± 0.011	2.269AsnLys: 2.269 ± 0.012	3.663AsnLeu: 3.663 ± 0.016	1.106AsnMet: 1.106 ± 0.008	1.957AsnAsn: 1.957 ± 0.014	2.234AsnPro: 2.234 ± 0.013	1.801AsnGln: 1.801 ± 0.014	2.01AsnArg: 2.01 ± 0.011	3.332AsnSer: 3.332 ± 0.018	2.428AsnThr: 2.428 ± 0.016	2.335AsnVal: 2.335 ± 0.013	0.455AsnTrp: 0.455 ± 0.005	1.168AsnTyr: 1.168 ± 0.008	0.0AsnXaa: 0.0 ± 0.0
Pro	3.956ProAla: 3.956 ± 0.021	1.063ProCys: 1.063 ± 0.011	2.858ProAsp: 2.858 ± 0.016	3.65ProGlu: 3.65 ± 0.019	1.822ProPhe: 1.822 ± 0.012	3.846ProGly: 3.846 ± 0.034	1.516ProHis: 1.516 ± 0.014	1.866ProIle: 1.866 ± 0.011	2.485ProLys: 2.485 ± 0.021	4.858ProLeu: 4.858 ± 0.021	1.009ProMet: 1.009 ± 0.009	1.924ProAsn: 1.924 ± 0.012	5.211ProPro: 5.211 ± 0.044	2.578ProGln: 2.578 ± 0.019	2.63ProArg: 2.63 ± 0.015	5.465ProSer: 5.465 ± 0.031	3.067ProThr: 3.067 ± 0.021	3.692ProVal: 3.692 ± 0.019	0.551ProTrp: 0.551 ± 0.007	1.394ProTyr: 1.394 ± 0.011	0.0ProXaa: 0.0 ± 0.0
Gln	3.025GlnAla: 3.025 ± 0.016	0.98GlnCys: 0.98 ± 0.011	2.285GlnAsp: 2.285 ± 0.013	3.429GlnGlu: 3.429 ± 0.022	1.368GlnPhe: 1.368 ± 0.009	2.645GlnGly: 2.645 ± 0.018	1.37GlnHis: 1.37 ± 0.012	1.924GlnIle: 1.924 ± 0.01	2.577GlnLys: 2.577 ± 0.018	4.365GlnLeu: 4.365 ± 0.022	1.142GlnMet: 1.142 ± 0.008	1.77GlnAsn: 1.77 ± 0.01	2.497GlnPro: 2.497 ± 0.017	3.29GlnGln: 3.29 ± 0.034	3.101GlnArg: 3.101 ± 0.016	3.559GlnSer: 3.559 ± 0.018	2.814GlnThr: 2.814 ± 0.029	2.828GlnVal: 2.828 ± 0.014	0.531GlnTrp: 0.531 ± 0.006	1.211GlnTyr: 1.211 ± 0.009	0.0GlnXaa: 0.0 ± 0.0
Arg	3.34ArgAla: 3.34 ± 0.015	1.267ArgCys: 1.267 ± 0.012	2.941ArgAsp: 2.941 ± 0.017	3.934ArgGlu: 3.934 ± 0.021	2.024ArgPhe: 2.024 ± 0.011	3.503ArgGly: 3.503 ± 0.02	1.593ArgHis: 1.593 ± 0.012	2.341ArgIle: 2.341 ± 0.012	3.461ArgLys: 3.461 ± 0.015	5.312ArgLeu: 5.312 ± 0.024	1.307ArgMet: 1.307 ± 0.009	2.081ArgAsn: 2.081 ± 0.011	2.895ArgPro: 2.895 ± 0.017	2.715ArgGln: 2.715 ± 0.024	4.296ArgArg: 4.296 ± 0.023	4.508ArgSer: 4.508 ± 0.022	2.895ArgThr: 2.895 ± 0.014	3.353ArgVal: 3.353 ± 0.016	0.69ArgTrp: 0.69 ± 0.007	1.533ArgTyr: 1.533 ± 0.01	0.0ArgXaa: 0.0 ± 0.0
Ser	5.52SerAla: 5.52 ± 0.02	2.139SerCys: 2.139 ± 0.015	4.394SerAsp: 4.394 ± 0.019	4.95SerGlu: 4.95 ± 0.022	3.238SerPhe: 3.238 ± 0.016	5.596SerGly: 5.596 ± 0.023	2.296SerHis: 2.296 ± 0.014	3.472SerIle: 3.472 ± 0.02	4.033SerLys: 4.033 ± 0.018	8.67SerLeu: 8.67 ± 0.035	1.878SerMet: 1.878 ± 0.01	3.079SerAsn: 3.079 ± 0.014	5.865SerPro: 5.865 ± 0.034	3.815SerGln: 3.815 ± 0.019	4.55SerArg: 4.55 ± 0.024	10.39SerSer: 10.39 ± 0.051	4.85SerThr: 4.85 ± 0.018	5.693SerVal: 5.693 ± 0.028	1.044SerTrp: 1.044 ± 0.008	2.246SerTyr: 2.246 ± 0.012	0.0SerXaa: 0.0 ± 0.0
Thr	3.977ThrAla: 3.977 ± 0.02	1.452ThrCys: 1.452 ± 0.015	3.004ThrAsp: 3.004 ± 0.025	3.769ThrGlu: 3.769 ± 0.018	2.212ThrPhe: 2.212 ± 0.012	3.741ThrGly: 3.741 ± 0.017	1.795ThrHis: 1.795 ± 0.039	2.465ThrIle: 2.465 ± 0.013	2.74ThrLys: 2.74 ± 0.015	5.54ThrLeu: 5.54 ± 0.018	1.244ThrMet: 1.244 ± 0.008	2.056ThrAsn: 2.056 ± 0.019	3.61ThrPro: 3.61 ± 0.021	2.424ThrGln: 2.424 ± 0.015	2.503ThrArg: 2.503 ± 0.014	4.873ThrSer: 4.873 ± 0.022	3.499ThrThr: 3.499 ± 0.033	4.216ThrVal: 4.216 ± 0.021	0.684ThrTrp: 0.684 ± 0.007	1.455ThrTyr: 1.455 ± 0.01	0.0ThrXaa: 0.0 ± 0.0
Val	3.924ValAla: 3.924 ± 0.018	2.217ValCys: 2.217 ± 0.043	3.22ValAsp: 3.22 ± 0.014	3.988ValGlu: 3.988 ± 0.016	2.852ValPhe: 2.852 ± 0.019	3.478ValGly: 3.478 ± 0.014	1.628ValHis: 1.628 ± 0.01	3.018ValIle: 3.018 ± 0.016	3.649ValLys: 3.649 ± 0.017	6.146ValLeu: 6.146 ± 0.022	1.59ValMet: 1.59 ± 0.011	2.524ValAsn: 2.524 ± 0.013	3.147ValPro: 3.147 ± 0.014	2.777ValGln: 2.777 ± 0.015	3.291ValArg: 3.291 ± 0.015	5.571ValSer: 5.571 ± 0.024	4.066ValThr: 4.066 ± 0.023	4.397ValVal: 4.397 ± 0.021	0.777ValTrp: 0.777 ± 0.008	1.916ValTyr: 1.916 ± 0.014	0.0ValXaa: 0.0 ± 0.0
Trp	0.663TrpAla: 0.663 ± 0.007	0.255TrpCys: 0.255 ± 0.004	0.663TrpAsp: 0.663 ± 0.007	0.735TrpGlu: 0.735 ± 0.007	0.486TrpPhe: 0.486 ± 0.005	0.638TrpGly: 0.638 ± 0.006	0.267TrpHis: 0.267 ± 0.004	0.601TrpIle: 0.601 ± 0.006	0.725TrpLys: 0.725 ± 0.005	1.172TrpLeu: 1.172 ± 0.009	0.358TrpMet: 0.358 ± 0.004	0.505TrpAsn: 0.505 ± 0.006	0.435TrpPro: 0.435 ± 0.006	0.469TrpGln: 0.469 ± 0.006	0.78TrpArg: 0.78 ± 0.007	0.999TrpSer: 0.999 ± 0.01	0.726TrpThr: 0.726 ± 0.009	0.707TrpVal: 0.707 ± 0.007	0.197TrpTrp: 0.197 ± 0.003	0.359TrpTyr: 0.359 ± 0.004	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.41TyrAla: 1.41 ± 0.01	0.752TyrCys: 0.752 ± 0.007	1.409TyrAsp: 1.409 ± 0.01	1.566TyrGlu: 1.566 ± 0.011	1.251TyrPhe: 1.251 ± 0.01	1.688TyrGly: 1.688 ± 0.012	0.799TyrHis: 0.799 ± 0.007	1.485TyrIle: 1.485 ± 0.011	1.472TyrLys: 1.472 ± 0.01	2.732TyrLeu: 2.732 ± 0.021	0.688TyrMet: 0.688 ± 0.006	1.218TyrAsn: 1.218 ± 0.01	1.324TyrPro: 1.324 ± 0.011	1.243TyrGln: 1.243 ± 0.009	1.657TyrArg: 1.657 ± 0.011	2.432TyrSer: 2.432 ± 0.014	1.669TyrThr: 1.669 ± 0.013	1.561TyrVal: 1.561 ± 0.01	0.41TyrTrp: 0.41 ± 0.005	1.026TyrTyr: 1.026 ± 0.009	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 37793 proteins (19526510 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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