Amino acid dipepetide frequency for Anthracocystis flocculosa PF-1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	19.487AlaAla: 19.487 ± 0.184	0.926AlaCys: 0.926 ± 0.023	6.258AlaAsp: 6.258 ± 0.051	6.215AlaGlu: 6.215 ± 0.068	3.172AlaPhe: 3.172 ± 0.04	9.178AlaGly: 9.178 ± 0.082	2.338AlaHis: 2.338 ± 0.032	3.752AlaIle: 3.752 ± 0.037	4.843AlaLys: 4.843 ± 0.054	8.861AlaLeu: 8.861 ± 0.07	2.143AlaMet: 2.143 ± 0.03	3.057AlaAsn: 3.057 ± 0.037	7.383AlaPro: 7.383 ± 0.085	4.469AlaGln: 4.469 ± 0.054	7.193AlaArg: 7.193 ± 0.064	12.796AlaSer: 12.796 ± 0.117	7.273AlaThr: 7.273 ± 0.067	6.024AlaVal: 6.024 ± 0.058	1.147AlaTrp: 1.147 ± 0.022	2.078AlaTyr: 2.078 ± 0.032	0.001AlaXaa: 0.001 ± 0.001
Cys	0.822CysAla: 0.822 ± 0.019	0.171CysCys: 0.171 ± 0.008	0.55CysAsp: 0.55 ± 0.014	0.45CysGlu: 0.45 ± 0.016	0.387CysPhe: 0.387 ± 0.013	0.726CysGly: 0.726 ± 0.021	0.252CysHis: 0.252 ± 0.009	0.472CysIle: 0.472 ± 0.012	0.376CysLys: 0.376 ± 0.013	0.948CysLeu: 0.948 ± 0.023	0.168CysMet: 0.168 ± 0.008	0.279CysAsn: 0.279 ± 0.011	0.518CysPro: 0.518 ± 0.018	0.341CysGln: 0.341 ± 0.012	0.678CysArg: 0.678 ± 0.018	0.733CysSer: 0.733 ± 0.022	0.534CysThr: 0.534 ± 0.021	0.595CysVal: 0.595 ± 0.017	0.146CysTrp: 0.146 ± 0.007	0.25CysTyr: 0.25 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	7.416AspAla: 7.416 ± 0.069	0.486AspCys: 0.486 ± 0.017	7.079AspAsp: 7.079 ± 0.115	5.423AspGlu: 5.423 ± 0.062	1.79AspPhe: 1.79 ± 0.027	5.654AspGly: 5.654 ± 0.057	1.319AspHis: 1.319 ± 0.025	1.946AspIle: 1.946 ± 0.029	2.096AspLys: 2.096 ± 0.038	4.997AspLeu: 4.997 ± 0.047	0.969AspMet: 0.969 ± 0.018	1.354AspAsn: 1.354 ± 0.024	3.614AspPro: 3.614 ± 0.038	1.98AspGln: 1.98 ± 0.028	3.799AspArg: 3.799 ± 0.044	3.982AspSer: 3.982 ± 0.045	2.529AspThr: 2.529 ± 0.031	3.867AspVal: 3.867 ± 0.047	0.74AspTrp: 0.74 ± 0.018	1.185AspTyr: 1.185 ± 0.022	0.0AspXaa: 0.0 ± 0.0
Glu	7.112GluAla: 7.112 ± 0.078	0.453GluCys: 0.453 ± 0.013	3.904GluAsp: 3.904 ± 0.054	4.54GluGlu: 4.54 ± 0.078	1.303GluPhe: 1.303 ± 0.027	4.224GluGly: 4.224 ± 0.046	1.27GluHis: 1.27 ± 0.023	2.04GluIle: 2.04 ± 0.032	2.39GluLys: 2.39 ± 0.038	4.84GluLeu: 4.84 ± 0.055	1.211GluMet: 1.211 ± 0.02	1.16GluAsn: 1.16 ± 0.024	2.65GluPro: 2.65 ± 0.038	2.468GluGln: 2.468 ± 0.036	4.649GluArg: 4.649 ± 0.056	3.613GluSer: 3.613 ± 0.039	2.711GluThr: 2.711 ± 0.034	3.284GluVal: 3.284 ± 0.041	0.721GluTrp: 0.721 ± 0.018	1.086GluTyr: 1.086 ± 0.024	0.001GluXaa: 0.001 ± 0.0
Phe	3.107PheAla: 3.107 ± 0.033	0.409PheCys: 0.409 ± 0.013	2.162PheAsp: 2.162 ± 0.032	1.782PheGlu: 1.782 ± 0.029	1.197PhePhe: 1.197 ± 0.025	2.726PheGly: 2.726 ± 0.047	0.703PheHis: 0.703 ± 0.015	1.048PheIle: 1.048 ± 0.024	1.06PheLys: 1.06 ± 0.023	2.648PheLeu: 2.648 ± 0.034	0.502PheMet: 0.502 ± 0.015	0.933PheAsn: 0.933 ± 0.02	1.406PhePro: 1.406 ± 0.026	1.005PheGln: 1.005 ± 0.019	1.758PheArg: 1.758 ± 0.028	2.405PheSer: 2.405 ± 0.034	1.469PheThr: 1.469 ± 0.026	2.053PheVal: 2.053 ± 0.032	0.431PheTrp: 0.431 ± 0.014	0.798PheTyr: 0.798 ± 0.022	0.0PheXaa: 0.0 ± 0.0
Gly	8.624GlyAla: 8.624 ± 0.081	0.72GlyCys: 0.72 ± 0.02	4.698GlyAsp: 4.698 ± 0.048	3.871GlyGlu: 3.871 ± 0.045	2.419GlyPhe: 2.419 ± 0.04	10.173GlyGly: 10.173 ± 0.129	1.944GlyHis: 1.944 ± 0.032	2.791GlyIle: 2.791 ± 0.032	3.402GlyLys: 3.402 ± 0.043	6.048GlyLeu: 6.048 ± 0.059	1.464GlyMet: 1.464 ± 0.028	2.106GlyAsn: 2.106 ± 0.039	4.383GlyPro: 4.383 ± 0.058	3.176GlyGln: 3.176 ± 0.043	5.279GlyArg: 5.279 ± 0.055	8.11GlySer: 8.11 ± 0.089	4.175GlyThr: 4.175 ± 0.052	4.146GlyVal: 4.146 ± 0.044	1.008GlyTrp: 1.008 ± 0.019	1.742GlyTyr: 1.742 ± 0.03	0.0GlyXaa: 0.0 ± 0.0
His	2.507HisAla: 2.507 ± 0.036	0.241HisCys: 0.241 ± 0.009	1.503HisAsp: 1.503 ± 0.027	1.191HisGlu: 1.191 ± 0.023	0.8HisPhe: 0.8 ± 0.019	1.96HisGly: 1.96 ± 0.033	1.225HisHis: 1.225 ± 0.041	0.836HisIle: 0.836 ± 0.019	0.685HisLys: 0.685 ± 0.016	2.343HisLeu: 2.343 ± 0.029	0.325HisMet: 0.325 ± 0.01	0.579HisAsn: 0.579 ± 0.017	1.812HisPro: 1.812 ± 0.03	1.16HisGln: 1.16 ± 0.037	1.847HisArg: 1.847 ± 0.031	1.862HisSer: 1.862 ± 0.031	1.091HisThr: 1.091 ± 0.019	1.316HisVal: 1.316 ± 0.022	0.254HisTrp: 0.254 ± 0.01	0.536HisTyr: 0.536 ± 0.014	0.0HisXaa: 0.0 ± 0.0
Ile	3.592IleAla: 3.592 ± 0.04	0.479IleCys: 0.479 ± 0.014	2.614IleAsp: 2.614 ± 0.033	2.289IleGlu: 2.289 ± 0.029	1.242IlePhe: 1.242 ± 0.024	2.472IleGly: 2.472 ± 0.033	0.812IleHis: 0.812 ± 0.018	1.258IleIle: 1.258 ± 0.025	1.588IleLys: 1.588 ± 0.025	3.113IleLeu: 3.113 ± 0.04	0.58IleMet: 0.58 ± 0.015	1.115IleAsn: 1.115 ± 0.024	1.943IlePro: 1.943 ± 0.028	1.29IleGln: 1.29 ± 0.025	2.383IleArg: 2.383 ± 0.032	2.712IleSer: 2.712 ± 0.035	1.684IleThr: 1.684 ± 0.029	2.394IleVal: 2.394 ± 0.037	0.447IleTrp: 0.447 ± 0.012	0.863IleTyr: 0.863 ± 0.019	0.0IleXaa: 0.0 ± 0.0
Lys	4.785LysAla: 4.785 ± 0.047	0.326LysCys: 0.326 ± 0.012	2.226LysAsp: 2.226 ± 0.036	2.397LysGlu: 2.397 ± 0.037	0.893LysPhe: 0.893 ± 0.021	2.829LysGly: 2.829 ± 0.039	0.874LysHis: 0.874 ± 0.018	1.377LysIle: 1.377 ± 0.028	2.62LysLys: 2.62 ± 0.052	3.45LysLeu: 3.45 ± 0.04	0.811LysMet: 0.811 ± 0.018	0.994LysAsn: 0.994 ± 0.025	2.311LysPro: 2.311 ± 0.035	1.702LysGln: 1.702 ± 0.029	3.512LysArg: 3.512 ± 0.043	2.701LysSer: 2.701 ± 0.038	2.175LysThr: 2.175 ± 0.032	2.518LysVal: 2.518 ± 0.035	0.448LysTrp: 0.448 ± 0.013	0.73LysTyr: 0.73 ± 0.019	0.001LysXaa: 0.001 ± 0.001
Leu	9.36LeuAla: 9.36 ± 0.073	1.042LeuCys: 1.042 ± 0.023	5.658LeuAsp: 5.658 ± 0.05	4.998LeuGlu: 4.998 ± 0.05	2.813LeuPhe: 2.813 ± 0.041	6.071LeuGly: 6.071 ± 0.056	2.054LeuHis: 2.054 ± 0.03	2.875LeuIle: 2.875 ± 0.041	3.197LeuLys: 3.197 ± 0.041	7.916LeuLeu: 7.916 ± 0.093	1.411LeuMet: 1.411 ± 0.025	2.325LeuAsn: 2.325 ± 0.03	5.732LeuPro: 5.732 ± 0.05	3.473LeuGln: 3.473 ± 0.042	6.136LeuArg: 6.136 ± 0.054	7.463LeuSer: 7.463 ± 0.057	4.083LeuThr: 4.083 ± 0.042	5.49LeuVal: 5.49 ± 0.061	0.913LeuTrp: 0.913 ± 0.02	1.845LeuTyr: 1.845 ± 0.029	0.0LeuXaa: 0.0 ± 0.0
Met	2.236MetAla: 2.236 ± 0.031	0.159MetCys: 0.159 ± 0.008	1.037MetAsp: 1.037 ± 0.022	0.85MetGlu: 0.85 ± 0.018	0.473MetPhe: 0.473 ± 0.013	1.307MetGly: 1.307 ± 0.026	0.393MetHis: 0.393 ± 0.012	0.61MetIle: 0.61 ± 0.014	0.603MetLys: 0.603 ± 0.015	1.704MetLeu: 1.704 ± 0.025	0.448MetMet: 0.448 ± 0.013	0.434MetAsn: 0.434 ± 0.013	1.344MetPro: 1.344 ± 0.025	0.806MetGln: 0.806 ± 0.021	1.243MetArg: 1.243 ± 0.019	1.707MetSer: 1.707 ± 0.028	1.055MetThr: 1.055 ± 0.019	1.074MetVal: 1.074 ± 0.021	0.188MetTrp: 0.188 ± 0.008	0.322MetTyr: 0.322 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	2.999AsnAla: 2.999 ± 0.031	0.238AsnCys: 0.238 ± 0.011	1.602AsnAsp: 1.602 ± 0.025	1.348AsnGlu: 1.348 ± 0.022	0.847AsnPhe: 0.847 ± 0.018	2.725AsnGly: 2.725 ± 0.045	0.588AsnHis: 0.588 ± 0.017	1.001AsnIle: 1.001 ± 0.023	1.03AsnLys: 1.03 ± 0.02	2.507AsnLeu: 2.507 ± 0.034	0.505AsnMet: 0.505 ± 0.016	0.878AsnAsn: 0.878 ± 0.025	1.739AsnPro: 1.739 ± 0.031	0.902AsnGln: 0.902 ± 0.018	1.66AsnArg: 1.66 ± 0.024	1.92AsnSer: 1.92 ± 0.033	1.314AsnThr: 1.314 ± 0.021	1.769AsnVal: 1.769 ± 0.026	0.298AsnTrp: 0.298 ± 0.012	0.585AsnTyr: 0.585 ± 0.016	0.0AsnXaa: 0.0 ± 0.0
Pro	8.173ProAla: 8.173 ± 0.087	0.431ProCys: 0.431 ± 0.015	3.185ProAsp: 3.185 ± 0.035	2.928ProGlu: 2.928 ± 0.033	1.827ProPhe: 1.827 ± 0.028	4.54ProGly: 4.54 ± 0.061	1.572ProHis: 1.572 ± 0.033	1.997ProIle: 1.997 ± 0.03	2.129ProLys: 2.129 ± 0.034	5.089ProLeu: 5.089 ± 0.046	1.024ProMet: 1.024 ± 0.025	1.69ProAsn: 1.69 ± 0.029	6.537ProPro: 6.537 ± 0.1	2.561ProGln: 2.561 ± 0.04	4.129ProArg: 4.129 ± 0.047	8.381ProSer: 8.381 ± 0.099	4.258ProThr: 4.258 ± 0.046	3.199ProVal: 3.199 ± 0.034	0.588ProTrp: 0.588 ± 0.016	1.246ProTyr: 1.246 ± 0.026	0.001ProXaa: 0.001 ± 0.001
Gln	4.582GlnAla: 4.582 ± 0.05	0.296GlnCys: 0.296 ± 0.012	2.098GlnAsp: 2.098 ± 0.028	1.989GlnGlu: 1.989 ± 0.03	0.868GlnPhe: 0.868 ± 0.017	2.823GlnGly: 2.823 ± 0.039	1.496GlnHis: 1.496 ± 0.04	1.374GlnIle: 1.374 ± 0.024	1.42GlnLys: 1.42 ± 0.024	3.597GlnLeu: 3.597 ± 0.045	0.808GlnMet: 0.808 ± 0.022	0.978GlnAsn: 0.978 ± 0.018	3.185GlnPro: 3.185 ± 0.05	4.688GlnGln: 4.688 ± 0.143	3.472GlnArg: 3.472 ± 0.04	3.004GlnSer: 3.004 ± 0.04	1.963GlnThr: 1.963 ± 0.029	2.046GlnVal: 2.046 ± 0.031	0.428GlnTrp: 0.428 ± 0.011	0.76GlnTyr: 0.76 ± 0.017	0.0GlnXaa: 0.0 ± 0.0
Arg	6.737ArgAla: 6.737 ± 0.052	0.7ArgCys: 0.7 ± 0.018	3.994ArgAsp: 3.994 ± 0.049	3.796ArgGlu: 3.796 ± 0.046	2.162ArgPhe: 2.162 ± 0.031	4.784ArgGly: 4.784 ± 0.056	1.885ArgHis: 1.885 ± 0.033	2.787ArgIle: 2.787 ± 0.04	3.279ArgLys: 3.279 ± 0.043	6.18ArgLeu: 6.18 ± 0.053	1.337ArgMet: 1.337 ± 0.02	1.998ArgAsn: 1.998 ± 0.027	4.684ArgPro: 4.684 ± 0.055	3.193ArgGln: 3.193 ± 0.043	6.797ArgArg: 6.797 ± 0.089	6.56ArgSer: 6.56 ± 0.074	3.719ArgThr: 3.719 ± 0.043	3.194ArgVal: 3.194 ± 0.041	0.869ArgTrp: 0.869 ± 0.019	1.511ArgTyr: 1.511 ± 0.026	0.002ArgXaa: 0.002 ± 0.001
Ser	10.93SerAla: 10.93 ± 0.106	0.712SerCys: 0.712 ± 0.021	4.887SerAsp: 4.887 ± 0.056	3.753SerGlu: 3.753 ± 0.043	2.698SerPhe: 2.698 ± 0.034	7.325SerGly: 7.325 ± 0.086	2.106SerHis: 2.106 ± 0.032	3.284SerIle: 3.284 ± 0.04	3.269SerLys: 3.269 ± 0.041	7.67SerLeu: 7.67 ± 0.059	1.676SerMet: 1.676 ± 0.024	2.595SerAsn: 2.595 ± 0.042	6.574SerPro: 6.574 ± 0.087	3.428SerGln: 3.428 ± 0.042	6.175SerArg: 6.175 ± 0.067	14.29SerSer: 14.29 ± 0.166	6.557SerThr: 6.557 ± 0.069	4.418SerVal: 4.418 ± 0.043	0.881SerTrp: 0.881 ± 0.016	1.754SerTyr: 1.754 ± 0.027	0.001SerXaa: 0.001 ± 0.0
Thr	7.033ThrAla: 7.033 ± 0.066	0.534ThrCys: 0.534 ± 0.018	2.686ThrAsp: 2.686 ± 0.04	2.394ThrGlu: 2.394 ± 0.034	1.744ThrPhe: 1.744 ± 0.031	4.096ThrGly: 4.096 ± 0.048	1.103ThrHis: 1.103 ± 0.022	2.113ThrIle: 2.113 ± 0.03	2.016ThrLys: 2.016 ± 0.028	4.774ThrLeu: 4.774 ± 0.045	0.996ThrMet: 0.996 ± 0.021	1.397ThrAsn: 1.397 ± 0.026	4.426ThrPro: 4.426 ± 0.054	1.737ThrGln: 1.737 ± 0.028	3.271ThrArg: 3.271 ± 0.035	5.914ThrSer: 5.914 ± 0.061	4.237ThrThr: 4.237 ± 0.055	3.134ThrVal: 3.134 ± 0.035	0.612ThrTrp: 0.612 ± 0.018	1.139ThrTyr: 1.139 ± 0.024	0.001ThrXaa: 0.001 ± 0.001
Val	6.157ValAla: 6.157 ± 0.053	0.642ValCys: 0.642 ± 0.021	3.922ValAsp: 3.922 ± 0.041	3.764ValGlu: 3.764 ± 0.046	1.832ValPhe: 1.832 ± 0.031	4.222ValGly: 4.222 ± 0.044	1.293ValHis: 1.293 ± 0.024	1.967ValIle: 1.967 ± 0.036	2.406ValLys: 2.406 ± 0.039	5.071ValLeu: 5.071 ± 0.05	0.994ValMet: 0.994 ± 0.02	1.499ValAsn: 1.499 ± 0.027	3.533ValPro: 3.533 ± 0.041	2.197ValGln: 2.197 ± 0.03	3.845ValArg: 3.845 ± 0.042	4.305ValSer: 4.305 ± 0.045	2.629ValThr: 2.629 ± 0.034	4.114ValVal: 4.114 ± 0.049	0.737ValTrp: 0.737 ± 0.019	1.313ValTyr: 1.313 ± 0.028	0.001ValXaa: 0.001 ± 0.001
Trp	0.929TrpAla: 0.929 ± 0.018	0.173TrpCys: 0.173 ± 0.007	0.719TrpAsp: 0.719 ± 0.02	0.566TrpGlu: 0.566 ± 0.016	0.352TrpPhe: 0.352 ± 0.012	0.669TrpGly: 0.669 ± 0.017	0.287TrpHis: 0.287 ± 0.011	0.539TrpIle: 0.539 ± 0.017	0.553TrpLys: 0.553 ± 0.015	1.082TrpLeu: 1.082 ± 0.021	0.262TrpMet: 0.262 ± 0.01	0.425TrpAsn: 0.425 ± 0.013	0.539TrpPro: 0.539 ± 0.013	0.541TrpGln: 0.541 ± 0.014	0.856TrpArg: 0.856 ± 0.02	1.0TrpSer: 1.0 ± 0.022	0.77TrpThr: 0.77 ± 0.019	0.546TrpVal: 0.546 ± 0.016	0.218TrpTrp: 0.218 ± 0.01	0.307TrpTyr: 0.307 ± 0.012	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.004TyrAla: 2.004 ± 0.034	0.259TyrCys: 0.259 ± 0.011	1.439TyrAsp: 1.439 ± 0.026	1.09TyrGlu: 1.09 ± 0.019	0.782TyrPhe: 0.782 ± 0.021	1.775TyrGly: 1.775 ± 0.035	0.561TyrHis: 0.561 ± 0.014	0.803TyrIle: 0.803 ± 0.02	0.718TyrLys: 0.718 ± 0.021	2.015TyrLeu: 2.015 ± 0.034	0.358TyrMet: 0.358 ± 0.012	0.658TyrAsn: 0.658 ± 0.015	1.171TyrPro: 1.171 ± 0.024	0.756TyrGln: 0.756 ± 0.018	1.483TyrArg: 1.483 ± 0.024	1.526TyrSer: 1.526 ± 0.031	1.134TyrThr: 1.134 ± 0.024	1.26TyrVal: 1.26 ± 0.02	0.259TyrTrp: 0.259 ± 0.01	0.576TyrTyr: 0.576 ± 0.016	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.002XaaAla: 0.002 ± 0.001	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.001XaaGly: 0.001 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.001XaaLeu: 0.001 ± 0.001	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.001XaaPro: 0.001 ± 0.001	0.0XaaGln: 0.0 ± 0.0	0.001XaaArg: 0.001 ± 0.001	0.001XaaSer: 0.001 ± 0.001	0.0XaaThr: 0.0 ± 0.0	0.001XaaVal: 0.001 ± 0.001	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.06XaaXaa: 0.06 ± 0.013

Statistics based on 4425 proteins (2781444 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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