Amino acid dipepetide frequency for Ficedula albicollis (Collared flycatcher) (Muscicapa albicollis)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.005AlaAla: 7.005 ± 0.057	1.358AlaCys: 1.358 ± 0.019	3.003AlaAsp: 3.003 ± 0.024	5.031AlaGlu: 5.031 ± 0.037	2.552AlaPhe: 2.552 ± 0.018	4.815AlaGly: 4.815 ± 0.038	1.454AlaHis: 1.454 ± 0.019	2.803AlaIle: 2.803 ± 0.023	3.601AlaLys: 3.601 ± 0.027	6.99AlaLeu: 6.99 ± 0.051	1.529AlaMet: 1.529 ± 0.016	2.092AlaAsn: 2.092 ± 0.017	3.715AlaPro: 3.715 ± 0.037	3.076AlaGln: 3.076 ± 0.027	3.433AlaArg: 3.433 ± 0.03	5.303AlaSer: 5.303 ± 0.033	3.326AlaThr: 3.326 ± 0.029	5.089AlaVal: 5.089 ± 0.035	0.759AlaTrp: 0.759 ± 0.01	1.503AlaTyr: 1.503 ± 0.014	0.001AlaXaa: 0.001 ± 0.0
Cys	1.335CysAla: 1.335 ± 0.021	0.688CysCys: 0.688 ± 0.014	1.059CysAsp: 1.059 ± 0.017	1.312CysGlu: 1.312 ± 0.019	0.886CysPhe: 0.886 ± 0.012	1.58CysGly: 1.58 ± 0.041	0.726CysHis: 0.726 ± 0.018	1.049CysIle: 1.049 ± 0.014	1.221CysLys: 1.221 ± 0.015	2.245CysLeu: 2.245 ± 0.023	0.437CysMet: 0.437 ± 0.007	0.837CysAsn: 0.837 ± 0.012	1.617CysPro: 1.617 ± 0.032	1.138CysGln: 1.138 ± 0.018	1.359CysArg: 1.359 ± 0.02	2.126CysSer: 2.126 ± 0.023	1.212CysThr: 1.212 ± 0.017	1.524CysVal: 1.524 ± 0.033	0.308CysTrp: 0.308 ± 0.008	0.637CysTyr: 0.637 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	2.901AspAla: 2.901 ± 0.021	1.075AspCys: 1.075 ± 0.014	2.688AspAsp: 2.688 ± 0.032	3.552AspGlu: 3.552 ± 0.03	2.151AspPhe: 2.151 ± 0.018	3.374AspGly: 3.374 ± 0.03	1.071AspHis: 1.071 ± 0.012	2.701AspIle: 2.701 ± 0.021	2.637AspLys: 2.637 ± 0.02	4.773AspLeu: 4.773 ± 0.029	1.108AspMet: 1.108 ± 0.012	1.779AspAsn: 1.779 ± 0.021	2.72AspPro: 2.72 ± 0.021	1.726AspGln: 1.726 ± 0.019	2.397AspArg: 2.397 ± 0.026	4.177AspSer: 4.177 ± 0.029	2.579AspThr: 2.579 ± 0.023	3.11AspVal: 3.11 ± 0.022	0.618AspTrp: 0.618 ± 0.011	1.527AspTyr: 1.527 ± 0.016	0.0AspXaa: 0.0 ± 0.0
Glu	4.808GluAla: 4.808 ± 0.038	1.322GluCys: 1.322 ± 0.023	4.359GluAsp: 4.359 ± 0.029	7.993GluGlu: 7.993 ± 0.068	2.118GluPhe: 2.118 ± 0.017	4.171GluGly: 4.171 ± 0.048	1.556GluHis: 1.556 ± 0.014	3.292GluIle: 3.292 ± 0.023	5.486GluLys: 5.486 ± 0.049	6.493GluLeu: 6.493 ± 0.048	1.748GluMet: 1.748 ± 0.017	3.215GluAsn: 3.215 ± 0.027	2.933GluPro: 2.933 ± 0.031	3.349GluGln: 3.349 ± 0.028	4.199GluArg: 4.199 ± 0.067	4.467GluSer: 4.467 ± 0.029	3.329GluThr: 3.329 ± 0.027	4.102GluVal: 4.102 ± 0.026	0.719GluTrp: 0.719 ± 0.009	1.69GluTyr: 1.69 ± 0.024	0.0GluXaa: 0.0 ± 0.0
Phe	2.053PheAla: 2.053 ± 0.019	0.962PheCys: 0.962 ± 0.013	1.692PheAsp: 1.692 ± 0.014	2.004PheGlu: 2.004 ± 0.017	1.674PhePhe: 1.674 ± 0.019	2.265PheGly: 2.265 ± 0.025	1.061PheHis: 1.061 ± 0.011	1.875PheIle: 1.875 ± 0.019	1.818PheLys: 1.818 ± 0.016	4.055PheLeu: 4.055 ± 0.033	0.76PheMet: 0.76 ± 0.01	1.365PheAsn: 1.365 ± 0.014	2.173PhePro: 2.173 ± 0.031	1.82PheGln: 1.82 ± 0.019	1.882PheArg: 1.882 ± 0.018	3.466PheSer: 3.466 ± 0.04	2.06PheThr: 2.06 ± 0.024	2.276PheVal: 2.276 ± 0.02	0.499PheTrp: 0.499 ± 0.009	1.224PheTyr: 1.224 ± 0.015	0.001PheXaa: 0.001 ± 0.0
Gly	4.322GlyAla: 4.322 ± 0.04	1.41GlyCys: 1.41 ± 0.029	3.185GlyAsp: 3.185 ± 0.032	4.007GlyGlu: 4.007 ± 0.041	2.488GlyPhe: 2.488 ± 0.027	6.645GlyGly: 6.645 ± 0.155	1.711GlyHis: 1.711 ± 0.023	2.935GlyIle: 2.935 ± 0.028	4.09GlyLys: 4.09 ± 0.074	5.402GlyLeu: 5.402 ± 0.036	1.438GlyMet: 1.438 ± 0.019	2.453GlyAsn: 2.453 ± 0.024	3.302GlyPro: 3.302 ± 0.064	2.768GlyGln: 2.768 ± 0.026	3.604GlyArg: 3.604 ± 0.035	5.75GlySer: 5.75 ± 0.051	3.744GlyThr: 3.744 ± 0.037	3.646GlyVal: 3.646 ± 0.042	0.857GlyTrp: 0.857 ± 0.016	1.822GlyTyr: 1.822 ± 0.019	0.0GlyXaa: 0.0 ± 0.0
His	1.302HisAla: 1.302 ± 0.016	0.759HisCys: 0.759 ± 0.019	0.888HisAsp: 0.888 ± 0.01	1.307HisGlu: 1.307 ± 0.014	1.087HisPhe: 1.087 ± 0.017	1.596HisGly: 1.596 ± 0.021	0.879HisHis: 0.879 ± 0.015	1.265HisIle: 1.265 ± 0.015	1.285HisLys: 1.285 ± 0.015	2.77HisLeu: 2.77 ± 0.029	0.558HisMet: 0.558 ± 0.01	0.904HisAsn: 0.904 ± 0.011	1.735HisPro: 1.735 ± 0.025	1.169HisGln: 1.169 ± 0.015	1.537HisArg: 1.537 ± 0.02	2.291HisSer: 2.291 ± 0.023	1.344HisThr: 1.344 ± 0.029	1.474HisVal: 1.474 ± 0.015	0.347HisTrp: 0.347 ± 0.008	0.84HisTyr: 0.84 ± 0.011	0.0HisXaa: 0.0 ± 0.0
Ile	2.727IleAla: 2.727 ± 0.022	1.126IleCys: 1.126 ± 0.016	2.118IleAsp: 2.118 ± 0.021	2.627IleGlu: 2.627 ± 0.021	1.954IlePhe: 1.954 ± 0.019	2.284IleGly: 2.284 ± 0.02	1.272IleHis: 1.272 ± 0.018	2.444IleIle: 2.444 ± 0.026	2.724IleLys: 2.724 ± 0.024	4.584IleLeu: 4.584 ± 0.03	0.984IleMet: 0.984 ± 0.011	1.937IleAsn: 1.937 ± 0.021	2.939IlePro: 2.939 ± 0.031	2.304IleGln: 2.304 ± 0.02	2.37IleArg: 2.37 ± 0.017	3.845IleSer: 3.845 ± 0.029	2.612IleThr: 2.612 ± 0.031	2.622IleVal: 2.622 ± 0.024	0.526IleTrp: 0.526 ± 0.01	1.439IleTyr: 1.439 ± 0.017	0.0IleXaa: 0.0 ± 0.0
Lys	3.999LysAla: 3.999 ± 0.029	1.148LysCys: 1.148 ± 0.015	3.262LysAsp: 3.262 ± 0.028	5.561LysGlu: 5.561 ± 0.079	1.769LysPhe: 1.769 ± 0.016	3.631LysGly: 3.631 ± 0.076	1.46LysHis: 1.46 ± 0.015	2.893LysIle: 2.893 ± 0.023	5.051LysLys: 5.051 ± 0.048	5.287LysLeu: 5.287 ± 0.037	1.469LysMet: 1.469 ± 0.015	2.505LysAsn: 2.505 ± 0.019	2.979LysPro: 2.979 ± 0.028	2.778LysGln: 2.778 ± 0.024	3.377LysArg: 3.377 ± 0.028	4.038LysSer: 4.038 ± 0.027	3.082LysThr: 3.082 ± 0.025	3.522LysVal: 3.522 ± 0.029	0.637LysTrp: 0.637 ± 0.01	1.685LysTyr: 1.685 ± 0.018	0.001LysXaa: 0.001 ± 0.0
Leu	6.516LeuAla: 6.516 ± 0.038	2.418LeuCys: 2.418 ± 0.027	4.638LeuAsp: 4.638 ± 0.031	6.983LeuGlu: 6.983 ± 0.049	3.45LeuPhe: 3.45 ± 0.031	5.543LeuGly: 5.543 ± 0.039	2.709LeuHis: 2.709 ± 0.031	3.849LeuIle: 3.849 ± 0.03	5.924LeuLys: 5.924 ± 0.04	10.386LeuLeu: 10.386 ± 0.07	1.938LeuMet: 1.938 ± 0.016	3.531LeuAsn: 3.531 ± 0.023	5.796LeuPro: 5.796 ± 0.048	5.736LeuGln: 5.736 ± 0.045	5.504LeuArg: 5.504 ± 0.034	8.041LeuSer: 8.041 ± 0.049	4.705LeuThr: 4.705 ± 0.028	5.346LeuVal: 5.346 ± 0.037	1.11LeuTrp: 1.11 ± 0.014	2.649LeuTyr: 2.649 ± 0.022	0.0LeuXaa: 0.0 ± 0.0
Met	1.738MetAla: 1.738 ± 0.015	0.43MetCys: 0.43 ± 0.007	1.259MetAsp: 1.259 ± 0.013	1.88MetGlu: 1.88 ± 0.018	0.773MetPhe: 0.773 ± 0.009	1.325MetGly: 1.325 ± 0.021	0.478MetHis: 0.478 ± 0.008	0.864MetIle: 0.864 ± 0.011	1.502MetLys: 1.502 ± 0.014	1.935MetLeu: 1.935 ± 0.016	0.566MetMet: 0.566 ± 0.01	0.909MetAsn: 0.909 ± 0.012	1.017MetPro: 1.017 ± 0.012	0.979MetGln: 0.979 ± 0.013	1.043MetArg: 1.043 ± 0.012	1.558MetSer: 1.558 ± 0.015	1.053MetThr: 1.053 ± 0.012	1.356MetVal: 1.356 ± 0.013	0.242MetTrp: 0.242 ± 0.005	0.595MetTyr: 0.595 ± 0.008	0.0MetXaa: 0.0 ± 0.0
Asn	2.217AsnAla: 2.217 ± 0.018	0.902AsnCys: 0.902 ± 0.013	1.557AsnAsp: 1.557 ± 0.019	2.337AsnGlu: 2.337 ± 0.022	1.51AsnPhe: 1.51 ± 0.017	2.606AsnGly: 2.606 ± 0.031	0.898AsnHis: 0.898 ± 0.011	2.21AsnIle: 2.21 ± 0.019	2.305AsnLys: 2.305 ± 0.02	3.732AsnLeu: 3.732 ± 0.025	0.911AsnMet: 0.911 ± 0.011	1.638AsnAsn: 1.638 ± 0.019	2.204AsnPro: 2.204 ± 0.025	1.593AsnGln: 1.593 ± 0.018	1.811AsnArg: 1.811 ± 0.016	3.243AsnSer: 3.243 ± 0.025	2.022AsnThr: 2.022 ± 0.018	2.282AsnVal: 2.282 ± 0.017	0.45AsnTrp: 0.45 ± 0.008	1.173AsnTyr: 1.173 ± 0.013	0.0AsnXaa: 0.0 ± 0.0
Pro	4.823ProAla: 4.823 ± 0.047	1.324ProCys: 1.324 ± 0.025	2.607ProAsp: 2.607 ± 0.021	4.096ProGlu: 4.096 ± 0.03	1.976ProPhe: 1.976 ± 0.027	4.89ProGly: 4.89 ± 0.097	1.38ProHis: 1.38 ± 0.02	1.925ProIle: 1.925 ± 0.027	2.75ProLys: 2.75 ± 0.029	4.949ProLeu: 4.949 ± 0.035	0.949ProMet: 0.949 ± 0.013	1.818ProAsn: 1.818 ± 0.022	7.888ProPro: 7.888 ± 0.203	2.587ProGln: 2.587 ± 0.028	3.071ProArg: 3.071 ± 0.033	5.464ProSer: 5.464 ± 0.062	2.639ProThr: 2.639 ± 0.031	3.98ProVal: 3.98 ± 0.041	0.633ProTrp: 0.633 ± 0.014	1.397ProTyr: 1.397 ± 0.015	0.001ProXaa: 0.001 ± 0.0
Gln	3.198GlnAla: 3.198 ± 0.028	1.013GlnCys: 1.013 ± 0.017	2.268GlnAsp: 2.268 ± 0.021	3.783GlnGlu: 3.783 ± 0.035	1.412GlnPhe: 1.412 ± 0.017	2.796GlnGly: 2.796 ± 0.03	1.352GlnHis: 1.352 ± 0.017	2.047GlnIle: 2.047 ± 0.016	3.024GlnLys: 3.024 ± 0.026	4.717GlnLeu: 4.717 ± 0.036	1.07GlnMet: 1.07 ± 0.014	1.917GlnAsn: 1.917 ± 0.018	2.61GlnPro: 2.61 ± 0.031	3.095GlnGln: 3.095 ± 0.047	2.821GlnArg: 2.821 ± 0.028	3.253GlnSer: 3.253 ± 0.038	2.263GlnThr: 2.263 ± 0.023	2.733GlnVal: 2.733 ± 0.025	0.535GlnTrp: 0.535 ± 0.009	1.205GlnTyr: 1.205 ± 0.012	0.0GlnXaa: 0.0 ± 0.0
Arg	3.728ArgAla: 3.728 ± 0.025	1.342ArgCys: 1.342 ± 0.027	2.79ArgAsp: 2.79 ± 0.029	3.892ArgGlu: 3.892 ± 0.04	1.856ArgPhe: 1.856 ± 0.015	3.443ArgGly: 3.443 ± 0.039	1.446ArgHis: 1.446 ± 0.018	2.475ArgIle: 2.475 ± 0.02	3.907ArgLys: 3.907 ± 0.074	4.97ArgLeu: 4.97 ± 0.036	1.175ArgMet: 1.175 ± 0.013	2.143ArgAsn: 2.143 ± 0.02	2.714ArgPro: 2.714 ± 0.029	2.52ArgGln: 2.52 ± 0.022	4.124ArgArg: 4.124 ± 0.043	4.198ArgSer: 4.198 ± 0.037	2.635ArgThr: 2.635 ± 0.017	3.051ArgVal: 3.051 ± 0.027	0.688ArgTrp: 0.688 ± 0.013	1.521ArgTyr: 1.521 ± 0.017	0.0ArgXaa: 0.0 ± 0.0
Ser	5.51SerAla: 5.51 ± 0.038	2.016SerCys: 2.016 ± 0.02	3.873SerAsp: 3.873 ± 0.028	5.048SerGlu: 5.048 ± 0.035	3.056SerPhe: 3.056 ± 0.035	5.318SerGly: 5.318 ± 0.038	2.105SerHis: 2.105 ± 0.023	3.461SerIle: 3.461 ± 0.029	4.226SerLys: 4.226 ± 0.033	8.166SerLeu: 8.166 ± 0.056	1.589SerMet: 1.589 ± 0.015	2.761SerAsn: 2.761 ± 0.024	5.868SerPro: 5.868 ± 0.055	3.833SerGln: 3.833 ± 0.04	4.43SerArg: 4.43 ± 0.039	9.446SerSer: 9.446 ± 0.085	4.412SerThr: 4.412 ± 0.038	5.078SerVal: 5.078 ± 0.036	1.01SerTrp: 1.01 ± 0.013	2.126SerTyr: 2.126 ± 0.02	0.0SerXaa: 0.0 ± 0.0
Thr	3.95ThrAla: 3.95 ± 0.024	1.311ThrCys: 1.311 ± 0.02	2.544ThrAsp: 2.544 ± 0.024	3.561ThrGlu: 3.561 ± 0.031	2.064ThrPhe: 2.064 ± 0.018	3.572ThrGly: 3.572 ± 0.044	1.167ThrHis: 1.167 ± 0.028	2.342ThrIle: 2.342 ± 0.019	2.674ThrLys: 2.674 ± 0.025	4.996ThrLeu: 4.996 ± 0.031	1.046ThrMet: 1.046 ± 0.011	1.763ThrAsn: 1.763 ± 0.016	3.198ThrPro: 3.198 ± 0.035	2.068ThrGln: 2.068 ± 0.023	2.317ThrArg: 2.317 ± 0.021	4.404ThrSer: 4.404 ± 0.039	2.767ThrThr: 2.767 ± 0.037	3.926ThrVal: 3.926 ± 0.037	0.69ThrTrp: 0.69 ± 0.014	1.425ThrTyr: 1.425 ± 0.015	0.0ThrXaa: 0.0 ± 0.0
Val	4.141ValAla: 4.141 ± 0.033	1.712ValCys: 1.712 ± 0.041	2.835ValAsp: 2.835 ± 0.025	3.85ValGlu: 3.85 ± 0.029	2.502ValPhe: 2.502 ± 0.025	3.293ValGly: 3.293 ± 0.028	1.531ValHis: 1.531 ± 0.02	2.935ValIle: 2.935 ± 0.027	3.524ValLys: 3.524 ± 0.029	6.37ValLeu: 6.37 ± 0.041	1.293ValMet: 1.293 ± 0.013	2.303ValAsn: 2.303 ± 0.022	3.955ValPro: 3.955 ± 0.045	2.792ValGln: 2.792 ± 0.025	3.01ValArg: 3.01 ± 0.026	5.064ValSer: 5.064 ± 0.039	3.854ValThr: 3.854 ± 0.038	4.058ValVal: 4.058 ± 0.032	0.729ValTrp: 0.729 ± 0.013	1.689ValTyr: 1.689 ± 0.018	0.001ValXaa: 0.001 ± 0.0
Trp	0.745TrpAla: 0.745 ± 0.014	0.266TrpCys: 0.266 ± 0.01	0.689TrpAsp: 0.689 ± 0.012	0.794TrpGlu: 0.794 ± 0.012	0.437TrpPhe: 0.437 ± 0.008	0.715TrpGly: 0.715 ± 0.014	0.325TrpHis: 0.325 ± 0.007	0.604TrpIle: 0.604 ± 0.011	0.831TrpLys: 0.831 ± 0.013	1.204TrpLeu: 1.204 ± 0.016	0.316TrpMet: 0.316 ± 0.006	0.554TrpAsn: 0.554 ± 0.011	0.456TrpPro: 0.456 ± 0.008	0.548TrpGln: 0.548 ± 0.009	0.698TrpArg: 0.698 ± 0.01	0.89TrpSer: 0.89 ± 0.015	0.638TrpThr: 0.638 ± 0.013	0.667TrpVal: 0.667 ± 0.011	0.19TrpTrp: 0.19 ± 0.005	0.353TrpTyr: 0.353 ± 0.007	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.421TyrAla: 1.421 ± 0.016	0.712TyrCys: 0.712 ± 0.01	1.349TyrAsp: 1.349 ± 0.016	1.729TyrGlu: 1.729 ± 0.018	1.272TyrPhe: 1.272 ± 0.015	1.719TyrGly: 1.719 ± 0.019	0.753TyrHis: 0.753 ± 0.011	1.471TyrIle: 1.471 ± 0.018	1.552TyrLys: 1.552 ± 0.016	2.748TyrLeu: 2.748 ± 0.022	0.617TyrMet: 0.617 ± 0.008	1.178TyrAsn: 1.178 ± 0.013	1.326TyrPro: 1.326 ± 0.017	1.233TyrGln: 1.233 ± 0.013	1.63TyrArg: 1.63 ± 0.018	2.309TyrSer: 2.309 ± 0.021	1.51TyrThr: 1.51 ± 0.017	1.599TyrVal: 1.599 ± 0.016	0.373TyrTrp: 0.373 ± 0.01	0.998TyrTyr: 0.998 ± 0.012	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.001XaaAla: 0.001 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.001XaaAsp: 0.001 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.001XaaGly: 0.001 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.001XaaLeu: 0.001 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.001XaaPro: 0.001 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.001XaaSer: 0.001 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.035XaaXaa: 0.035 ± 0.011

Statistics based on 15922 proteins (8677355 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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