Amino acid dipepetide frequency for Tetrapisispora phaffii (strain ATCC 24235 / CBS 4417 / NBRC 1672 / NRRL Y-8282 / UCD 70-5) (Yeast) (Fabospora phaffii)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.45AlaAla: 3.45 ± 0.06
0.572AlaCys: 0.572 ± 0.014
2.548AlaAsp: 2.548 ± 0.032
2.895AlaGlu: 2.895 ± 0.053
2.073AlaPhe: 2.073 ± 0.03
2.563AlaGly: 2.563 ± 0.042
0.908AlaHis: 0.908 ± 0.019
3.583AlaIle: 3.583 ± 0.047
3.573AlaLys: 3.573 ± 0.041
4.691AlaLeu: 4.691 ± 0.055
1.146AlaMet: 1.146 ± 0.021
3.129AlaAsn: 3.129 ± 0.035
1.789AlaPro: 1.789 ± 0.037
1.736AlaGln: 1.736 ± 0.035
1.939AlaArg: 1.939 ± 0.034
4.465AlaSer: 4.465 ± 0.057
3.333AlaThr: 3.333 ± 0.049
2.932AlaVal: 2.932 ± 0.041
0.421AlaTrp: 0.421 ± 0.013
1.599AlaTyr: 1.599 ± 0.027
0.001AlaXaa: 0.001 ± 0.0
Cys
0.5CysAla: 0.5 ± 0.013
0.238CysCys: 0.238 ± 0.01
0.639CysAsp: 0.639 ± 0.015
0.529CysGlu: 0.529 ± 0.016
0.58CysPhe: 0.58 ± 0.017
0.711CysGly: 0.711 ± 0.02
0.285CysHis: 0.285 ± 0.012
0.937CysIle: 0.937 ± 0.018
0.758CysLys: 0.758 ± 0.017
1.106CysLeu: 1.106 ± 0.02
0.224CysMet: 0.224 ± 0.01
0.689CysAsn: 0.689 ± 0.019
0.416CysPro: 0.416 ± 0.016
0.356CysGln: 0.356 ± 0.011
0.408CysArg: 0.408 ± 0.015
0.943CysSer: 0.943 ± 0.02
0.546CysThr: 0.546 ± 0.016
0.663CysVal: 0.663 ± 0.016
0.137CysTrp: 0.137 ± 0.008
0.46CysTyr: 0.46 ± 0.013
0.0CysXaa: 0.0 ± 0.0
Asp
2.876AspAla: 2.876 ± 0.039
0.615AspCys: 0.615 ± 0.016
4.822AspAsp: 4.822 ± 0.069
4.886AspGlu: 4.886 ± 0.053
2.809AspPhe: 2.809 ± 0.035
2.761AspGly: 2.761 ± 0.036
1.006AspHis: 1.006 ± 0.021
5.215AspIle: 5.215 ± 0.052
4.147AspLys: 4.147 ± 0.041
5.619AspLeu: 5.619 ± 0.046
1.252AspMet: 1.252 ± 0.022
4.342AspAsn: 4.342 ± 0.048
2.177AspPro: 2.177 ± 0.031
1.669AspGln: 1.669 ± 0.03
1.927AspArg: 1.927 ± 0.028
5.145AspSer: 5.145 ± 0.047
3.181AspThr: 3.181 ± 0.033
3.476AspVal: 3.476 ± 0.039
0.592AspTrp: 0.592 ± 0.019
2.354AspTyr: 2.354 ± 0.037
0.0AspXaa: 0.0 ± 0.0
Glu
3.19GluAla: 3.19 ± 0.051
0.56GluCys: 0.56 ± 0.016
4.338GluAsp: 4.338 ± 0.053
5.86GluGlu: 5.86 ± 0.075
2.884GluPhe: 2.884 ± 0.033
2.541GluGly: 2.541 ± 0.039
1.211GluHis: 1.211 ± 0.022
4.763GluIle: 4.763 ± 0.047
5.496GluLys: 5.496 ± 0.064
6.775GluLeu: 6.775 ± 0.061
1.369GluMet: 1.369 ± 0.022
5.083GluAsn: 5.083 ± 0.05
1.78GluPro: 1.78 ± 0.033
2.584GluGln: 2.584 ± 0.039
2.571GluArg: 2.571 ± 0.032
5.085GluSer: 5.085 ± 0.099
3.895GluThr: 3.895 ± 0.066
3.462GluVal: 3.462 ± 0.039
0.606GluTrp: 0.606 ± 0.014
2.502GluTyr: 2.502 ± 0.034
0.0GluXaa: 0.0 ± 0.0
Phe
2.131PheAla: 2.131 ± 0.032
0.515PheCys: 0.515 ± 0.015
2.874PheAsp: 2.874 ± 0.034
2.959PheGlu: 2.959 ± 0.038
1.914PhePhe: 1.914 ± 0.037
2.44PheGly: 2.44 ± 0.047
0.88PheHis: 0.88 ± 0.02
3.354PheIle: 3.354 ± 0.045
3.435PheLys: 3.435 ± 0.035
3.942PheLeu: 3.942 ± 0.05
0.896PheMet: 0.896 ± 0.019
3.141PheAsn: 3.141 ± 0.036
1.639PhePro: 1.639 ± 0.028
1.762PheGln: 1.762 ± 0.029
1.475PheArg: 1.475 ± 0.026
3.655PheSer: 3.655 ± 0.038
2.476PheThr: 2.476 ± 0.034
2.389PheVal: 2.389 ± 0.031
0.476PheTrp: 0.476 ± 0.015
1.645PheTyr: 1.645 ± 0.028
0.0PheXaa: 0.0 ± 0.0
Gly
2.441GlyAla: 2.441 ± 0.042
0.618GlyCys: 0.618 ± 0.016
2.591GlyAsp: 2.591 ± 0.035
2.603GlyGlu: 2.603 ± 0.039
2.192GlyPhe: 2.192 ± 0.035
2.703GlyGly: 2.703 ± 0.059
0.955GlyHis: 0.955 ± 0.023
3.491GlyIle: 3.491 ± 0.04
3.434GlyLys: 3.434 ± 0.039
4.138GlyLeu: 4.138 ± 0.047
0.94GlyMet: 0.94 ± 0.024
3.165GlyAsn: 3.165 ± 0.046
1.282GlyPro: 1.282 ± 0.026
1.389GlyGln: 1.389 ± 0.033
1.786GlyArg: 1.786 ± 0.031
4.338GlySer: 4.338 ± 0.05
2.833GlyThr: 2.833 ± 0.04
2.722GlyVal: 2.722 ± 0.039
0.53GlyTrp: 0.53 ± 0.013
1.792GlyTyr: 1.792 ± 0.033
0.0GlyXaa: 0.0 ± 0.0
His
0.863HisAla: 0.863 ± 0.019
0.268HisCys: 0.268 ± 0.011
1.13HisAsp: 1.13 ± 0.02
1.115HisGlu: 1.115 ± 0.02
0.926HisPhe: 0.926 ± 0.021
0.961HisGly: 0.961 ± 0.018
0.541HisHis: 0.541 ± 0.016
1.468HisIle: 1.468 ± 0.021
1.279HisLys: 1.279 ± 0.024
1.929HisLeu: 1.929 ± 0.025
0.418HisMet: 0.418 ± 0.012
1.305HisAsn: 1.305 ± 0.024
0.895HisPro: 0.895 ± 0.019
0.712HisGln: 0.712 ± 0.017
0.824HisArg: 0.824 ± 0.02
1.791HisSer: 1.791 ± 0.028
0.996HisThr: 0.996 ± 0.021
1.033HisVal: 1.033 ± 0.019
0.21HisTrp: 0.21 ± 0.009
0.774HisTyr: 0.774 ± 0.019
0.0HisXaa: 0.0 ± 0.0
Ile
3.684IleAla: 3.684 ± 0.043
0.932IleCys: 0.932 ± 0.022
4.894IleAsp: 4.894 ± 0.046
5.055IleGlu: 5.055 ± 0.063
3.263IlePhe: 3.263 ± 0.044
3.23IleGly: 3.23 ± 0.039
1.371IleHis: 1.371 ± 0.022
5.33IleIle: 5.33 ± 0.067
5.693IleLys: 5.693 ± 0.063
6.909IleLeu: 6.909 ± 0.06
1.432IleMet: 1.432 ± 0.022
5.235IleAsn: 5.235 ± 0.052
3.308IlePro: 3.308 ± 0.035
2.674IleGln: 2.674 ± 0.033
2.803IleArg: 2.803 ± 0.035
6.722IleSer: 6.722 ± 0.063
4.232IleThr: 4.232 ± 0.043
4.051IleVal: 4.051 ± 0.042
0.731IleTrp: 0.731 ± 0.017
2.541IleTyr: 2.541 ± 0.037
0.001IleXaa: 0.001 ± 0.0
Lys
3.362LysAla: 3.362 ± 0.047
0.776LysCys: 0.776 ± 0.017
4.491LysAsp: 4.491 ± 0.042
5.545LysGlu: 5.545 ± 0.063
3.329LysPhe: 3.329 ± 0.039
2.812LysGly: 2.812 ± 0.029
1.574LysHis: 1.574 ± 0.027
5.761LysIle: 5.761 ± 0.056
7.164LysLys: 7.164 ± 0.075
7.911LysLeu: 7.911 ± 0.078
1.57LysMet: 1.57 ± 0.026
5.789LysAsn: 5.789 ± 0.053
2.694LysPro: 2.694 ± 0.033
2.984LysGln: 2.984 ± 0.04
3.576LysArg: 3.576 ± 0.044
6.137LysSer: 6.137 ± 0.056
4.281LysThr: 4.281 ± 0.043
4.041LysVal: 4.041 ± 0.04
0.733LysTrp: 0.733 ± 0.019
3.225LysTyr: 3.225 ± 0.043
0.0LysXaa: 0.0 ± 0.0
Leu
4.644LeuAla: 4.644 ± 0.049
1.113LeuCys: 1.113 ± 0.022
5.441LeuAsp: 5.441 ± 0.051
6.086LeuGlu: 6.086 ± 0.057
4.229LeuPhe: 4.229 ± 0.058
4.036LeuGly: 4.036 ± 0.044
1.931LeuHis: 1.931 ± 0.032
6.35LeuIle: 6.35 ± 0.074
7.905LeuLys: 7.905 ± 0.061
9.488LeuLeu: 9.488 ± 0.081
1.917LeuMet: 1.917 ± 0.029
6.759LeuAsn: 6.759 ± 0.065
4.233LeuPro: 4.233 ± 0.046
4.022LeuGln: 4.022 ± 0.047
3.903LeuArg: 3.903 ± 0.043
8.357LeuSer: 8.357 ± 0.067
5.393LeuThr: 5.393 ± 0.052
4.864LeuVal: 4.864 ± 0.049
0.81LeuTrp: 0.81 ± 0.02
3.249LeuTyr: 3.249 ± 0.037
0.0LeuXaa: 0.0 ± 0.0
Met
1.125MetAla: 1.125 ± 0.023
0.21MetCys: 0.21 ± 0.01
1.291MetAsp: 1.291 ± 0.019
1.26MetGlu: 1.26 ± 0.024
0.869MetPhe: 0.869 ± 0.019
1.009MetGly: 1.009 ± 0.02
0.38MetHis: 0.38 ± 0.012
1.384MetIle: 1.384 ± 0.024
1.651MetLys: 1.651 ± 0.027
1.843MetLeu: 1.843 ± 0.028
0.496MetMet: 0.496 ± 0.014
1.611MetAsn: 1.611 ± 0.031
0.713MetPro: 0.713 ± 0.015
0.701MetGln: 0.701 ± 0.016
0.744MetArg: 0.744 ± 0.017
2.06MetSer: 2.06 ± 0.03
1.146MetThr: 1.146 ± 0.02
1.129MetVal: 1.129 ± 0.022
0.162MetTrp: 0.162 ± 0.008
0.601MetTyr: 0.601 ± 0.018
0.0MetXaa: 0.0 ± 0.0
Asn
3.31AsnAla: 3.31 ± 0.036
0.73AsnCys: 0.73 ± 0.02
4.993AsnAsp: 4.993 ± 0.055
5.168AsnGlu: 5.168 ± 0.06
2.948AsnPhe: 2.948 ± 0.036
3.509AsnGly: 3.509 ± 0.048
1.268AsnHis: 1.268 ± 0.024
5.97AsnIle: 5.97 ± 0.06
5.643AsnLys: 5.643 ± 0.056
6.006AsnLeu: 6.006 ± 0.057
1.449AsnMet: 1.449 ± 0.032
6.956AsnAsn: 6.956 ± 0.105
2.445AsnPro: 2.445 ± 0.036
2.302AsnGln: 2.302 ± 0.032
2.395AsnArg: 2.395 ± 0.034
6.974AsnSer: 6.974 ± 0.075
4.167AsnThr: 4.167 ± 0.046
3.834AsnVal: 3.834 ± 0.046
0.651AsnTrp: 0.651 ± 0.015
2.681AsnTyr: 2.681 ± 0.036
0.001AsnXaa: 0.001 ± 0.001
Pro
1.825ProAla: 1.825 ± 0.03
0.297ProCys: 0.297 ± 0.012
1.974ProAsp: 1.974 ± 0.029
2.566ProGlu: 2.566 ± 0.03
1.664ProPhe: 1.664 ± 0.026
1.606ProGly: 1.606 ± 0.03
0.737ProHis: 0.737 ± 0.017
2.866ProIle: 2.866 ± 0.038
2.612ProLys: 2.612 ± 0.033
3.534ProLeu: 3.534 ± 0.041
0.711ProMet: 0.711 ± 0.018
2.545ProAsn: 2.545 ± 0.038
1.747ProPro: 1.747 ± 0.045
1.42ProGln: 1.42 ± 0.03
1.29ProArg: 1.29 ± 0.023
3.453ProSer: 3.453 ± 0.051
2.435ProThr: 2.435 ± 0.03
2.416ProVal: 2.416 ± 0.04
0.356ProTrp: 0.356 ± 0.012
1.304ProTyr: 1.304 ± 0.024
0.0ProXaa: 0.0 ± 0.0
Gln
1.707GlnAla: 1.707 ± 0.033
0.38GlnCys: 0.38 ± 0.014
1.916GlnAsp: 1.916 ± 0.026
2.382GlnGlu: 2.382 ± 0.035
1.659GlnPhe: 1.659 ± 0.028
1.396GlnGly: 1.396 ± 0.026
0.791GlnHis: 0.791 ± 0.018
2.525GlnIle: 2.525 ± 0.03
2.78GlnLys: 2.78 ± 0.039
3.956GlnLeu: 3.956 ± 0.041
0.809GlnMet: 0.809 ± 0.02
2.675GlnAsn: 2.675 ± 0.032
1.31GlnPro: 1.31 ± 0.028
2.397GlnGln: 2.397 ± 0.077
1.624GlnArg: 1.624 ± 0.027
2.796GlnSer: 2.796 ± 0.037
1.966GlnThr: 1.966 ± 0.029
1.823GlnVal: 1.823 ± 0.029
0.329GlnTrp: 0.329 ± 0.009
1.447GlnTyr: 1.447 ± 0.026
0.001GlnXaa: 0.001 ± 0.001
Arg
1.908ArgAla: 1.908 ± 0.038
0.467ArgCys: 0.467 ± 0.013
2.098ArgAsp: 2.098 ± 0.03
2.433ArgGlu: 2.433 ± 0.035
1.7ArgPhe: 1.7 ± 0.028
1.798ArgGly: 1.798 ± 0.036
0.823ArgHis: 0.823 ± 0.017
2.736ArgIle: 2.736 ± 0.034
3.376ArgLys: 3.376 ± 0.043
3.656ArgLeu: 3.656 ± 0.04
0.801ArgMet: 0.801 ± 0.017
2.713ArgAsn: 2.713 ± 0.034
1.284ArgPro: 1.284 ± 0.025
1.404ArgGln: 1.404 ± 0.022
2.255ArgArg: 2.255 ± 0.036
3.236ArgSer: 3.236 ± 0.036
2.158ArgThr: 2.158 ± 0.031
2.022ArgVal: 2.022 ± 0.031
0.369ArgTrp: 0.369 ± 0.013
1.522ArgTyr: 1.522 ± 0.025
0.0ArgXaa: 0.0 ± 0.0
Ser
4.134SerAla: 4.134 ± 0.067
0.836SerCys: 0.836 ± 0.023
5.112SerAsp: 5.112 ± 0.052
5.13SerGlu: 5.13 ± 0.072
3.8SerPhe: 3.8 ± 0.039
3.984SerGly: 3.984 ± 0.047
1.707SerHis: 1.707 ± 0.025
6.769SerIle: 6.769 ± 0.075
7.117SerLys: 7.117 ± 0.059
8.245SerLeu: 8.245 ± 0.065
1.832SerMet: 1.832 ± 0.027
7.164SerAsn: 7.164 ± 0.07
3.139SerPro: 3.139 ± 0.046
3.198SerGln: 3.198 ± 0.043
3.332SerArg: 3.332 ± 0.041
10.026SerSer: 10.026 ± 0.182
6.064SerThr: 6.064 ± 0.106
4.588SerVal: 4.588 ± 0.048
0.75SerTrp: 0.75 ± 0.017
2.894SerTyr: 2.894 ± 0.039
0.0SerXaa: 0.0 ± 0.0
Thr
3.055ThrAla: 3.055 ± 0.039
0.581ThrCys: 0.581 ± 0.015
3.318ThrAsp: 3.318 ± 0.044
3.685ThrGlu: 3.685 ± 0.044
2.486ThrPhe: 2.486 ± 0.034
2.941ThrGly: 2.941 ± 0.045
1.077ThrHis: 1.077 ± 0.021
4.371ThrIle: 4.371 ± 0.051
4.298ThrLys: 4.298 ± 0.045
5.459ThrLeu: 5.459 ± 0.052
1.111ThrMet: 1.111 ± 0.021
4.167ThrAsn: 4.167 ± 0.042
2.592ThrPro: 2.592 ± 0.038
1.899ThrGln: 1.899 ± 0.028
2.086ThrArg: 2.086 ± 0.032
5.885ThrSer: 5.885 ± 0.135
4.306ThrThr: 4.306 ± 0.145
3.522ThrVal: 3.522 ± 0.045
0.532ThrTrp: 0.532 ± 0.016
1.938ThrTyr: 1.938 ± 0.05
0.0ThrXaa: 0.0 ± 0.0
Val
3.127ValAla: 3.127 ± 0.042
0.672ValCys: 0.672 ± 0.014
3.465ValAsp: 3.465 ± 0.043
3.638ValGlu: 3.638 ± 0.044
2.384ValPhe: 2.384 ± 0.034
2.636ValGly: 2.636 ± 0.035
1.03ValHis: 1.03 ± 0.025
3.908ValIle: 3.908 ± 0.044
3.998ValLys: 3.998 ± 0.041
4.996ValLeu: 4.996 ± 0.046
1.047ValMet: 1.047 ± 0.022
3.626ValAsn: 3.626 ± 0.038
2.362ValPro: 2.362 ± 0.03
1.783ValGln: 1.783 ± 0.027
2.045ValArg: 2.045 ± 0.035
4.791ValSer: 4.791 ± 0.044
3.46ValThr: 3.46 ± 0.055
3.26ValVal: 3.26 ± 0.04
0.513ValTrp: 0.513 ± 0.015
1.871ValTyr: 1.871 ± 0.026
0.0ValXaa: 0.0 ± 0.0
Trp
0.448TrpAla: 0.448 ± 0.015
0.196TrpCys: 0.196 ± 0.009
0.647TrpAsp: 0.647 ± 0.016
0.559TrpGlu: 0.559 ± 0.015
0.453TrpPhe: 0.453 ± 0.014
0.473TrpGly: 0.473 ± 0.015
0.179TrpHis: 0.179 ± 0.007
0.645TrpIle: 0.645 ± 0.019
0.801TrpLys: 0.801 ± 0.018
0.886TrpLeu: 0.886 ± 0.019
0.194TrpMet: 0.194 ± 0.008
0.663TrpAsn: 0.663 ± 0.018
0.247TrpPro: 0.247 ± 0.011
0.291TrpGln: 0.291 ± 0.011
0.438TrpArg: 0.438 ± 0.014
0.786TrpSer: 0.786 ± 0.02
0.484TrpThr: 0.484 ± 0.015
0.509TrpVal: 0.509 ± 0.013
0.126TrpTrp: 0.126 ± 0.007
0.381TrpTyr: 0.381 ± 0.014
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.568TyrAla: 1.568 ± 0.027
0.551TyrCys: 0.551 ± 0.014
2.289TyrAsp: 2.289 ± 0.03
2.2TyrGlu: 2.2 ± 0.032
1.834TyrPhe: 1.834 ± 0.033
1.835TyrGly: 1.835 ± 0.032
0.784TyrHis: 0.784 ± 0.015
2.665TyrIle: 2.665 ± 0.034
2.595TyrLys: 2.595 ± 0.034
3.642TyrLeu: 3.642 ± 0.04
0.771TyrMet: 0.771 ± 0.02
2.642TyrAsn: 2.642 ± 0.033
1.307TyrPro: 1.307 ± 0.023
1.383TyrGln: 1.383 ± 0.025
1.338TyrArg: 1.338 ± 0.025
3.174TyrSer: 3.174 ± 0.041
1.956TyrThr: 1.956 ± 0.043
1.877TyrVal: 1.877 ± 0.031
0.37TyrTrp: 0.37 ± 0.014
1.626TyrTyr: 1.626 ± 0.032
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.001XaaGlu: 0.001 ± 0.001
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.001XaaLeu: 0.001 ± 0.001
0.002XaaMet: 0.002 ± 0.001
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.013XaaXaa: 0.013 ± 0.006
Statistics based on 5238 proteins (2672966 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski