Amino acid dipepetide frequency for Arthroderma gypseum (strain ATCC MYA-4604 / CBS 118893) (Microsporum gypseum)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.617AlaAla: 8.617 ± 0.072
1.033AlaCys: 1.033 ± 0.018
4.042AlaAsp: 4.042 ± 0.032
5.034AlaGlu: 5.034 ± 0.037
2.899AlaPhe: 2.899 ± 0.029
5.612AlaGly: 5.612 ± 0.047
1.686AlaHis: 1.686 ± 0.023
4.303AlaIle: 4.303 ± 0.032
4.091AlaLys: 4.091 ± 0.032
7.27AlaLeu: 7.27 ± 0.054
1.847AlaMet: 1.847 ± 0.024
2.849AlaAsn: 2.849 ± 0.026
4.441AlaPro: 4.441 ± 0.047
3.164AlaGln: 3.164 ± 0.033
4.687AlaArg: 4.687 ± 0.037
7.266AlaSer: 7.266 ± 0.043
5.008AlaThr: 5.008 ± 0.034
5.123AlaVal: 5.123 ± 0.033
1.017AlaTrp: 1.017 ± 0.016
2.021AlaTyr: 2.021 ± 0.025
0.0AlaXaa: 0.0 ± 0.0
Cys
0.892CysAla: 0.892 ± 0.017
0.28CysCys: 0.28 ± 0.011
0.642CysAsp: 0.642 ± 0.014
0.63CysGlu: 0.63 ± 0.014
0.535CysPhe: 0.535 ± 0.011
0.958CysGly: 0.958 ± 0.018
0.348CysHis: 0.348 ± 0.011
0.754CysIle: 0.754 ± 0.016
0.557CysLys: 0.557 ± 0.014
1.325CysLeu: 1.325 ± 0.02
0.286CysMet: 0.286 ± 0.009
0.434CysAsn: 0.434 ± 0.009
0.715CysPro: 0.715 ± 0.016
0.465CysGln: 0.465 ± 0.011
0.804CysArg: 0.804 ± 0.014
1.004CysSer: 1.004 ± 0.018
0.669CysThr: 0.669 ± 0.014
0.768CysVal: 0.768 ± 0.014
0.183CysTrp: 0.183 ± 0.007
0.381CysTyr: 0.381 ± 0.009
0.0CysXaa: 0.0 ± 0.0
Asp
4.308AspAla: 4.308 ± 0.036
0.642AspCys: 0.642 ± 0.014
4.099AspAsp: 4.099 ± 0.047
4.532AspGlu: 4.532 ± 0.044
2.071AspPhe: 2.071 ± 0.023
4.01AspGly: 4.01 ± 0.035
1.19AspHis: 1.19 ± 0.02
3.452AspIle: 3.452 ± 0.03
2.583AspLys: 2.583 ± 0.026
4.764AspLeu: 4.764 ± 0.036
1.271AspMet: 1.271 ± 0.018
2.006AspAsn: 2.006 ± 0.021
3.124AspPro: 3.124 ± 0.029
1.823AspGln: 1.823 ± 0.021
3.032AspArg: 3.032 ± 0.031
4.296AspSer: 4.296 ± 0.035
3.116AspThr: 3.116 ± 0.025
3.339AspVal: 3.339 ± 0.03
0.785AspTrp: 0.785 ± 0.012
1.514AspTyr: 1.514 ± 0.018
0.0AspXaa: 0.0 ± 0.0
Glu
5.221GluAla: 5.221 ± 0.044
0.666GluCys: 0.666 ± 0.013
4.224GluAsp: 4.224 ± 0.041
5.73GluGlu: 5.73 ± 0.066
1.961GluPhe: 1.961 ± 0.026
3.643GluGly: 3.643 ± 0.031
1.345GluHis: 1.345 ± 0.017
3.221GluIle: 3.221 ± 0.032
4.083GluLys: 4.083 ± 0.043
5.248GluLeu: 5.248 ± 0.038
1.454GluMet: 1.454 ± 0.017
2.472GluAsn: 2.472 ± 0.023
2.975GluPro: 2.975 ± 0.045
2.538GluGln: 2.538 ± 0.027
3.895GluArg: 3.895 ± 0.034
4.485GluSer: 4.485 ± 0.039
3.45GluThr: 3.45 ± 0.04
3.5GluVal: 3.5 ± 0.031
0.809GluTrp: 0.809 ± 0.014
1.76GluTyr: 1.76 ± 0.023
0.0GluXaa: 0.0 ± 0.0
Phe
2.77PheAla: 2.77 ± 0.029
0.567PheCys: 0.567 ± 0.012
2.222PheAsp: 2.222 ± 0.023
2.069PheGlu: 2.069 ± 0.023
1.552PhePhe: 1.552 ± 0.022
2.641PheGly: 2.641 ± 0.03
0.91PheHis: 0.91 ± 0.016
1.92PheIle: 1.92 ± 0.022
1.581PheLys: 1.581 ± 0.021
3.356PheLeu: 3.356 ± 0.031
0.735PheMet: 0.735 ± 0.014
1.477PheAsn: 1.477 ± 0.021
1.929PhePro: 1.929 ± 0.021
1.341PheGln: 1.341 ± 0.018
1.956PheArg: 1.956 ± 0.026
3.179PheSer: 3.179 ± 0.029
2.159PheThr: 2.159 ± 0.025
2.207PheVal: 2.207 ± 0.028
0.573PheTrp: 0.573 ± 0.011
1.085PheTyr: 1.085 ± 0.018
0.0PheXaa: 0.0 ± 0.0
Gly
4.847GlyAla: 4.847 ± 0.041
0.899GlyCys: 0.899 ± 0.018
3.582GlyAsp: 3.582 ± 0.032
3.695GlyGlu: 3.695 ± 0.031
2.59GlyPhe: 2.59 ± 0.033
5.457GlyGly: 5.457 ± 0.062
1.662GlyHis: 1.662 ± 0.027
3.618GlyIle: 3.618 ± 0.041
3.66GlyLys: 3.66 ± 0.035
5.692GlyLeu: 5.692 ± 0.044
1.564GlyMet: 1.564 ± 0.022
2.545GlyAsn: 2.545 ± 0.024
3.243GlyPro: 3.243 ± 0.025
2.557GlyGln: 2.557 ± 0.026
4.125GlyArg: 4.125 ± 0.036
5.789GlySer: 5.789 ± 0.041
3.837GlyThr: 3.837 ± 0.031
4.131GlyVal: 4.131 ± 0.036
1.084GlyTrp: 1.084 ± 0.017
2.108GlyTyr: 2.108 ± 0.022
0.0GlyXaa: 0.0 ± 0.0
His
1.75HisAla: 1.75 ± 0.02
0.326HisCys: 0.326 ± 0.01
1.286HisAsp: 1.286 ± 0.018
1.29HisGlu: 1.29 ± 0.018
0.887HisPhe: 0.887 ± 0.015
1.773HisGly: 1.773 ± 0.021
0.967HisHis: 0.967 ± 0.022
1.338HisIle: 1.338 ± 0.018
0.95HisLys: 0.95 ± 0.017
2.18HisLeu: 2.18 ± 0.024
0.48HisMet: 0.48 ± 0.011
0.896HisAsn: 0.896 ± 0.015
1.702HisPro: 1.702 ± 0.02
1.137HisGln: 1.137 ± 0.021
1.565HisArg: 1.565 ± 0.021
2.042HisSer: 2.042 ± 0.025
1.315HisThr: 1.315 ± 0.02
1.315HisVal: 1.315 ± 0.017
0.31HisTrp: 0.31 ± 0.009
0.684HisTyr: 0.684 ± 0.014
0.0HisXaa: 0.0 ± 0.0
Ile
3.987IleAla: 3.987 ± 0.031
0.819IleCys: 0.819 ± 0.014
3.018IleAsp: 3.018 ± 0.026
3.031IleGlu: 3.031 ± 0.031
2.086IlePhe: 2.086 ± 0.025
3.165IleGly: 3.165 ± 0.032
1.287IleHis: 1.287 ± 0.018
2.743IleIle: 2.743 ± 0.029
2.444IleLys: 2.444 ± 0.023
4.833IleLeu: 4.833 ± 0.046
1.039IleMet: 1.039 ± 0.017
1.961IleAsn: 1.961 ± 0.022
3.417IlePro: 3.417 ± 0.031
2.008IleGln: 2.008 ± 0.023
3.009IleArg: 3.009 ± 0.029
4.491IleSer: 4.491 ± 0.038
2.921IleThr: 2.921 ± 0.029
3.069IleVal: 3.069 ± 0.03
0.699IleTrp: 0.699 ± 0.014
1.506IleTyr: 1.506 ± 0.02
0.0IleXaa: 0.0 ± 0.0
Lys
4.343LysAla: 4.343 ± 0.045
0.569LysCys: 0.569 ± 0.014
2.957LysAsp: 2.957 ± 0.031
3.745LysGlu: 3.745 ± 0.039
1.559LysPhe: 1.559 ± 0.019
3.151LysGly: 3.151 ± 0.028
1.162LysHis: 1.162 ± 0.018
2.456LysIle: 2.456 ± 0.027
3.698LysLys: 3.698 ± 0.059
4.364LysLeu: 4.364 ± 0.039
1.094LysMet: 1.094 ± 0.017
1.904LysAsn: 1.904 ± 0.021
3.052LysPro: 3.052 ± 0.034
2.079LysGln: 2.079 ± 0.024
3.627LysArg: 3.627 ± 0.037
3.861LysSer: 3.861 ± 0.033
2.864LysThr: 2.864 ± 0.028
2.874LysVal: 2.874 ± 0.025
0.673LysTrp: 0.673 ± 0.012
1.5LysTyr: 1.5 ± 0.02
0.0LysXaa: 0.0 ± 0.0
Leu
7.516LeuAla: 7.516 ± 0.046
1.205LeuCys: 1.205 ± 0.017
5.053LeuAsp: 5.053 ± 0.033
5.555LeuGlu: 5.555 ± 0.041
3.323LeuPhe: 3.323 ± 0.035
5.592LeuGly: 5.592 ± 0.044
2.238LeuHis: 2.238 ± 0.025
4.049LeuIle: 4.049 ± 0.036
4.455LeuLys: 4.455 ± 0.038
8.485LeuLeu: 8.485 ± 0.074
1.704LeuMet: 1.704 ± 0.021
3.266LeuAsn: 3.266 ± 0.03
5.563LeuPro: 5.563 ± 0.046
3.782LeuGln: 3.782 ± 0.033
5.732LeuArg: 5.732 ± 0.042
7.58LeuSer: 7.58 ± 0.053
4.734LeuThr: 4.734 ± 0.033
5.185LeuVal: 5.185 ± 0.037
1.099LeuTrp: 1.099 ± 0.018
2.348LeuTyr: 2.348 ± 0.028
0.0LeuXaa: 0.0 ± 0.0
Met
2.228MetAla: 2.228 ± 0.021
0.23MetCys: 0.23 ± 0.007
1.282MetAsp: 1.282 ± 0.016
1.368MetGlu: 1.368 ± 0.019
0.742MetPhe: 0.742 ± 0.014
1.468MetGly: 1.468 ± 0.021
0.47MetHis: 0.47 ± 0.01
1.0MetIle: 1.0 ± 0.015
1.131MetLys: 1.131 ± 0.015
1.843MetLeu: 1.843 ± 0.021
0.539MetMet: 0.539 ± 0.012
0.824MetAsn: 0.824 ± 0.013
1.184MetPro: 1.184 ± 0.019
0.843MetGln: 0.843 ± 0.015
1.173MetArg: 1.173 ± 0.016
1.78MetSer: 1.78 ± 0.022
1.21MetThr: 1.21 ± 0.016
1.3MetVal: 1.3 ± 0.018
0.232MetTrp: 0.232 ± 0.008
0.496MetTyr: 0.496 ± 0.01
0.0MetXaa: 0.0 ± 0.0
Asn
3.028AsnAla: 3.028 ± 0.026
0.48AsnCys: 0.48 ± 0.013
2.003AsnAsp: 2.003 ± 0.025
2.137AsnGlu: 2.137 ± 0.024
1.369AsnPhe: 1.369 ± 0.018
3.012AsnGly: 3.012 ± 0.032
0.894AsnHis: 0.894 ± 0.015
2.307AsnIle: 2.307 ± 0.025
1.745AsnLys: 1.745 ± 0.022
3.26AsnLeu: 3.26 ± 0.028
0.873AsnMet: 0.873 ± 0.016
1.759AsnAsn: 1.759 ± 0.027
2.53AsnPro: 2.53 ± 0.027
1.399AsnGln: 1.399 ± 0.022
2.061AsnArg: 2.061 ± 0.023
3.056AsnSer: 3.056 ± 0.028
2.35AsnThr: 2.35 ± 0.027
2.216AsnVal: 2.216 ± 0.022
0.512AsnTrp: 0.512 ± 0.011
1.043AsnTyr: 1.043 ± 0.015
0.0AsnXaa: 0.0 ± 0.0
Pro
5.197ProAla: 5.197 ± 0.048
0.583ProCys: 0.583 ± 0.014
3.188ProAsp: 3.188 ± 0.027
3.854ProGlu: 3.854 ± 0.041
2.066ProPhe: 2.066 ± 0.025
3.964ProGly: 3.964 ± 0.036
1.352ProHis: 1.352 ± 0.022
2.684ProIle: 2.684 ± 0.027
2.879ProLys: 2.879 ± 0.027
4.82ProLeu: 4.82 ± 0.038
1.066ProMet: 1.066 ± 0.018
2.264ProAsn: 2.264 ± 0.027
5.27ProPro: 5.27 ± 0.071
2.606ProGln: 2.606 ± 0.031
3.414ProArg: 3.414 ± 0.033
6.389ProSer: 6.389 ± 0.056
4.086ProThr: 4.086 ± 0.054
3.562ProVal: 3.562 ± 0.036
0.682ProTrp: 0.682 ± 0.012
1.5ProTyr: 1.5 ± 0.021
0.0ProXaa: 0.0 ± 0.0
Gln
3.349GlnAla: 3.349 ± 0.035
0.455GlnCys: 0.455 ± 0.012
1.975GlnAsp: 1.975 ± 0.022
2.417GlnGlu: 2.417 ± 0.024
1.314GlnPhe: 1.314 ± 0.02
2.422GlnGly: 2.422 ± 0.027
1.195GlnHis: 1.195 ± 0.021
1.849GlnIle: 1.849 ± 0.021
2.148GlnLys: 2.148 ± 0.022
3.541GlnLeu: 3.541 ± 0.033
0.832GlnMet: 0.832 ± 0.015
1.575GlnAsn: 1.575 ± 0.023
2.821GlnPro: 2.821 ± 0.041
3.092GlnGln: 3.092 ± 0.077
2.724GlnArg: 2.724 ± 0.03
3.258GlnSer: 3.258 ± 0.031
2.262GlnThr: 2.262 ± 0.028
2.103GlnVal: 2.103 ± 0.021
0.523GlnTrp: 0.523 ± 0.011
1.163GlnTyr: 1.163 ± 0.017
0.0GlnXaa: 0.0 ± 0.0
Arg
4.539ArgAla: 4.539 ± 0.035
0.762ArgCys: 0.762 ± 0.014
3.4ArgAsp: 3.4 ± 0.034
4.004ArgGlu: 4.004 ± 0.041
2.091ArgPhe: 2.091 ± 0.022
3.746ArgGly: 3.746 ± 0.042
1.603ArgHis: 1.603 ± 0.024
2.973ArgIle: 2.973 ± 0.024
3.554ArgLys: 3.554 ± 0.034
5.529ArgLeu: 5.529 ± 0.045
1.318ArgMet: 1.318 ± 0.018
2.376ArgAsn: 2.376 ± 0.025
3.558ArgPro: 3.558 ± 0.036
2.682ArgGln: 2.682 ± 0.026
5.246ArgArg: 5.246 ± 0.057
5.002ArgSer: 5.002 ± 0.046
3.189ArgThr: 3.189 ± 0.028
3.306ArgVal: 3.306 ± 0.029
0.864ArgTrp: 0.864 ± 0.013
1.715ArgTyr: 1.715 ± 0.019
0.0ArgXaa: 0.0 ± 0.0
Ser
6.547SerAla: 6.547 ± 0.042
0.964SerCys: 0.964 ± 0.016
4.181SerAsp: 4.181 ± 0.035
4.247SerGlu: 4.247 ± 0.041
3.092SerPhe: 3.092 ± 0.031
5.589SerGly: 5.589 ± 0.041
2.144SerHis: 2.144 ± 0.026
4.393SerIle: 4.393 ± 0.036
4.288SerLys: 4.288 ± 0.037
7.603SerLeu: 7.603 ± 0.048
1.859SerMet: 1.859 ± 0.022
3.37SerAsn: 3.37 ± 0.03
5.846SerPro: 5.846 ± 0.059
3.554SerGln: 3.554 ± 0.033
5.513SerArg: 5.513 ± 0.05
9.819SerSer: 9.819 ± 0.081
5.9SerThr: 5.9 ± 0.046
4.55SerVal: 4.55 ± 0.033
1.074SerTrp: 1.074 ± 0.017
2.161SerTyr: 2.161 ± 0.029
0.0SerXaa: 0.0 ± 0.0
Thr
5.147ThrAla: 5.147 ± 0.039
0.752ThrCys: 0.752 ± 0.015
2.803ThrAsp: 2.803 ± 0.025
3.209ThrGlu: 3.209 ± 0.039
2.118ThrPhe: 2.118 ± 0.022
4.049ThrGly: 4.049 ± 0.039
1.288ThrHis: 1.288 ± 0.019
3.138ThrIle: 3.138 ± 0.032
2.718ThrLys: 2.718 ± 0.027
5.149ThrLeu: 5.149 ± 0.037
1.184ThrMet: 1.184 ± 0.016
2.159ThrAsn: 2.159 ± 0.026
4.484ThrPro: 4.484 ± 0.047
2.082ThrGln: 2.082 ± 0.023
3.104ThrArg: 3.104 ± 0.027
5.591ThrSer: 5.591 ± 0.042
4.205ThrThr: 4.205 ± 0.043
3.56ThrVal: 3.56 ± 0.035
0.752ThrTrp: 0.752 ± 0.013
1.541ThrTyr: 1.541 ± 0.02
0.0ThrXaa: 0.0 ± 0.0
Val
4.761ValAla: 4.761 ± 0.038
0.814ValCys: 0.814 ± 0.014
3.569ValAsp: 3.569 ± 0.031
3.817ValGlu: 3.817 ± 0.033
2.32ValPhe: 2.32 ± 0.023
3.66ValGly: 3.66 ± 0.035
1.322ValHis: 1.322 ± 0.018
3.049ValIle: 3.049 ± 0.031
2.993ValLys: 2.993 ± 0.031
5.284ValLeu: 5.284 ± 0.041
1.251ValMet: 1.251 ± 0.017
2.192ValAsn: 2.192 ± 0.024
3.448ValPro: 3.448 ± 0.034
2.215ValGln: 2.215 ± 0.023
3.253ValArg: 3.253 ± 0.023
4.664ValSer: 4.664 ± 0.033
3.351ValThr: 3.351 ± 0.033
3.923ValVal: 3.923 ± 0.035
0.753ValTrp: 0.753 ± 0.015
1.676ValTyr: 1.676 ± 0.019
0.0ValXaa: 0.0 ± 0.0
Trp
1.004TrpAla: 1.004 ± 0.018
0.176TrpCys: 0.176 ± 0.007
0.828TrpAsp: 0.828 ± 0.016
0.806TrpGlu: 0.806 ± 0.015
0.473TrpPhe: 0.473 ± 0.011
0.804TrpGly: 0.804 ± 0.014
0.328TrpHis: 0.328 ± 0.01
0.728TrpIle: 0.728 ± 0.015
0.811TrpLys: 0.811 ± 0.014
1.226TrpLeu: 1.226 ± 0.022
0.345TrpMet: 0.345 ± 0.01
0.597TrpAsn: 0.597 ± 0.012
0.56TrpPro: 0.56 ± 0.012
0.495TrpGln: 0.495 ± 0.012
0.889TrpArg: 0.889 ± 0.014
0.982TrpSer: 0.982 ± 0.015
0.802TrpThr: 0.802 ± 0.013
0.787TrpVal: 0.787 ± 0.014
0.245TrpTrp: 0.245 ± 0.008
0.387TrpTyr: 0.387 ± 0.01
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.958TyrAla: 1.958 ± 0.022
0.41TyrCys: 0.41 ± 0.01
1.604TyrAsp: 1.604 ± 0.02
1.509TyrGlu: 1.509 ± 0.017
1.183TyrPhe: 1.183 ± 0.02
1.97TyrGly: 1.97 ± 0.025
0.801TyrHis: 0.801 ± 0.014
1.555TyrIle: 1.555 ± 0.019
1.161TyrLys: 1.161 ± 0.016
2.692TyrLeu: 2.692 ± 0.025
0.602TyrMet: 0.602 ± 0.013
1.108TyrAsn: 1.108 ± 0.016
1.566TyrPro: 1.566 ± 0.021
1.156TyrGln: 1.156 ± 0.019
1.647TyrArg: 1.647 ± 0.022
2.161TyrSer: 2.161 ± 0.022
1.605TyrThr: 1.605 ± 0.017
1.495TyrVal: 1.495 ± 0.019
0.404TyrTrp: 0.404 ± 0.011
0.909TyrTyr: 0.909 ± 0.014
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 8921 proteins (4257366 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski