Amino acid dipepetide frequency for Gigaspora rosea

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	2.601AlaAla: 2.601 ± 0.026	0.758AlaCys: 0.758 ± 0.009	2.577AlaAsp: 2.577 ± 0.021	2.939AlaGlu: 2.939 ± 0.026	2.39AlaPhe: 2.39 ± 0.022	2.045AlaGly: 2.045 ± 0.02	0.974AlaHis: 0.974 ± 0.01	4.113AlaIle: 4.113 ± 0.023	3.579AlaLys: 3.579 ± 0.02	5.448AlaLeu: 5.448 ± 0.047	0.973AlaMet: 0.973 ± 0.01	2.864AlaAsn: 2.864 ± 0.019	1.737AlaPro: 1.737 ± 0.018	1.718AlaGln: 1.718 ± 0.015	2.062AlaArg: 2.062 ± 0.018	3.569AlaSer: 3.569 ± 0.022	2.806AlaThr: 2.806 ± 0.02	2.403AlaVal: 2.403 ± 0.02	0.555AlaTrp: 0.555 ± 0.008	1.803AlaTyr: 1.803 ± 0.016	0.001AlaXaa: 0.001 ± 0.0
Cys	0.718CysAla: 0.718 ± 0.009	0.333CysCys: 0.333 ± 0.008	0.997CysAsp: 0.997 ± 0.012	0.975CysGlu: 0.975 ± 0.012	0.785CysPhe: 0.785 ± 0.011	0.982CysGly: 0.982 ± 0.012	0.386CysHis: 0.386 ± 0.008	1.134CysIle: 1.134 ± 0.01	1.508CysLys: 1.508 ± 0.022	1.531CysLeu: 1.531 ± 0.013	0.381CysMet: 0.381 ± 0.006	1.044CysAsn: 1.044 ± 0.011	0.65CysPro: 0.65 ± 0.009	0.611CysGln: 0.611 ± 0.008	0.685CysArg: 0.685 ± 0.01	1.166CysSer: 1.166 ± 0.013	0.754CysThr: 0.754 ± 0.009	0.754CysVal: 0.754 ± 0.01	0.318CysTrp: 0.318 ± 0.007	0.908CysTyr: 0.908 ± 0.018	0.0CysXaa: 0.0 ± 0.0
Asp	2.643AspAla: 2.643 ± 0.025	0.755AspCys: 0.755 ± 0.01	4.205AspAsp: 4.205 ± 0.033	4.413AspGlu: 4.413 ± 0.026	2.694AspPhe: 2.694 ± 0.016	2.579AspGly: 2.579 ± 0.02	1.049AspHis: 1.049 ± 0.011	4.982AspIle: 4.982 ± 0.024	3.995AspLys: 3.995 ± 0.024	5.674AspLeu: 5.674 ± 0.032	1.129AspMet: 1.129 ± 0.012	3.85AspAsn: 3.85 ± 0.025	2.376AspPro: 2.376 ± 0.017	1.865AspGln: 1.865 ± 0.018	1.956AspArg: 1.956 ± 0.014	3.989AspSer: 3.989 ± 0.022	2.634AspThr: 2.634 ± 0.019	2.828AspVal: 2.828 ± 0.023	0.655AspTrp: 0.655 ± 0.009	2.266AspTyr: 2.266 ± 0.017	0.0AspXaa: 0.0 ± 0.0
Glu	3.164GluAla: 3.164 ± 0.021	0.919GluCys: 0.919 ± 0.01	3.6GluAsp: 3.6 ± 0.026	5.556GluGlu: 5.556 ± 0.038	3.205GluPhe: 3.205 ± 0.019	2.565GluGly: 2.565 ± 0.024	1.309GluHis: 1.309 ± 0.012	6.415GluIle: 6.415 ± 0.032	5.734GluLys: 5.734 ± 0.033	6.516GluLeu: 6.516 ± 0.033	1.433GluMet: 1.433 ± 0.014	4.97GluAsn: 4.97 ± 0.026	2.024GluPro: 2.024 ± 0.02	2.388GluGln: 2.388 ± 0.02	2.816GluArg: 2.816 ± 0.022	4.736GluSer: 4.736 ± 0.025	3.489GluThr: 3.489 ± 0.024	3.363GluVal: 3.363 ± 0.026	0.868GluTrp: 0.868 ± 0.011	2.572GluTyr: 2.572 ± 0.018	0.0GluXaa: 0.0 ± 0.0
Phe	2.253PheAla: 2.253 ± 0.016	0.833PheCys: 0.833 ± 0.01	2.89PheAsp: 2.89 ± 0.017	3.027PheGlu: 3.027 ± 0.022	2.326PhePhe: 2.326 ± 0.022	2.794PheGly: 2.794 ± 0.02	1.09PheHis: 1.09 ± 0.011	3.829PheIle: 3.829 ± 0.027	3.163PheLys: 3.163 ± 0.019	4.366PheLeu: 4.366 ± 0.025	1.006PheMet: 1.006 ± 0.012	3.004PheAsn: 3.004 ± 0.02	1.578PhePro: 1.578 ± 0.015	1.802PheGln: 1.802 ± 0.013	1.8PheArg: 1.8 ± 0.014	3.648PheSer: 3.648 ± 0.024	2.499PheThr: 2.499 ± 0.017	2.427PheVal: 2.427 ± 0.019	0.58PheTrp: 0.58 ± 0.009	1.918PheTyr: 1.918 ± 0.015	0.0PheXaa: 0.0 ± 0.0
Gly	2.069GlyAla: 2.069 ± 0.017	0.771GlyCys: 0.771 ± 0.011	2.223GlyAsp: 2.223 ± 0.018	2.521GlyGlu: 2.521 ± 0.016	2.265GlyPhe: 2.265 ± 0.019	3.007GlyGly: 3.007 ± 0.03	1.133GlyHis: 1.133 ± 0.014	4.165GlyIle: 4.165 ± 0.028	3.573GlyLys: 3.573 ± 0.027	4.042GlyLeu: 4.042 ± 0.025	0.907GlyMet: 0.907 ± 0.011	2.715GlyAsn: 2.715 ± 0.021	1.473GlyPro: 1.473 ± 0.015	1.55GlyGln: 1.55 ± 0.015	1.958GlyArg: 1.958 ± 0.015	3.528GlySer: 3.528 ± 0.024	2.575GlyThr: 2.575 ± 0.017	2.74GlyVal: 2.74 ± 0.021	0.593GlyTrp: 0.593 ± 0.009	2.07GlyTyr: 2.07 ± 0.018	0.0GlyXaa: 0.0 ± 0.0
His	1.006HisAla: 1.006 ± 0.012	0.445HisCys: 0.445 ± 0.007	1.138HisAsp: 1.138 ± 0.012	1.373HisGlu: 1.373 ± 0.016	0.992HisPhe: 0.992 ± 0.011	1.03HisGly: 1.03 ± 0.013	0.621HisHis: 0.621 ± 0.01	1.635HisIle: 1.635 ± 0.013	1.515HisLys: 1.515 ± 0.015	2.057HisLeu: 2.057 ± 0.016	0.456HisMet: 0.456 ± 0.007	1.337HisAsn: 1.337 ± 0.014	1.026HisPro: 1.026 ± 0.01	0.822HisGln: 0.822 ± 0.01	1.002HisArg: 1.002 ± 0.011	1.811HisSer: 1.811 ± 0.016	1.003HisThr: 1.003 ± 0.013	1.134HisVal: 1.134 ± 0.014	0.274HisTrp: 0.274 ± 0.005	0.889HisTyr: 0.889 ± 0.01	0.0HisXaa: 0.0 ± 0.0
Ile	4.022IleAla: 4.022 ± 0.027	1.472IleCys: 1.472 ± 0.013	4.616IleAsp: 4.616 ± 0.023	5.42IleGlu: 5.42 ± 0.027	3.872IlePhe: 3.872 ± 0.024	3.616IleGly: 3.616 ± 0.028	1.847IleHis: 1.847 ± 0.016	6.801IleIle: 6.801 ± 0.037	6.102IleLys: 6.102 ± 0.032	7.623IleLeu: 7.623 ± 0.034	1.763IleMet: 1.763 ± 0.012	5.397IleAsn: 5.397 ± 0.032	3.601IlePro: 3.601 ± 0.021	2.913IleGln: 2.913 ± 0.019	3.362IleArg: 3.362 ± 0.021	6.499IleSer: 6.499 ± 0.031	4.462IleThr: 4.462 ± 0.022	4.111IleVal: 4.111 ± 0.023	0.909IleTrp: 0.909 ± 0.01	3.439IleTyr: 3.439 ± 0.022	0.0IleXaa: 0.0 ± 0.0
Lys	3.901LysAla: 3.901 ± 0.029	1.293LysCys: 1.293 ± 0.013	4.24LysAsp: 4.24 ± 0.028	5.719LysGlu: 5.719 ± 0.034	3.421LysPhe: 3.421 ± 0.018	2.84LysGly: 2.84 ± 0.021	1.609LysHis: 1.609 ± 0.015	6.25LysIle: 6.25 ± 0.031	7.09LysLys: 7.09 ± 0.043	7.015LysLeu: 7.015 ± 0.028	1.531LysMet: 1.531 ± 0.014	5.887LysAsn: 5.887 ± 0.032	2.577LysPro: 2.577 ± 0.018	2.78LysGln: 2.78 ± 0.019	3.817LysArg: 3.817 ± 0.024	5.608LysSer: 5.608 ± 0.029	3.83LysThr: 3.83 ± 0.025	3.695LysVal: 3.695 ± 0.023	0.914LysTrp: 0.914 ± 0.01	3.234LysTyr: 3.234 ± 0.019	0.0LysXaa: 0.0 ± 0.0
Leu	4.989LeuAla: 4.989 ± 0.032	1.869LeuCys: 1.869 ± 0.023	5.207LeuAsp: 5.207 ± 0.032	6.687LeuGlu: 6.687 ± 0.04	4.103LeuPhe: 4.103 ± 0.026	4.318LeuGly: 4.318 ± 0.029	2.121LeuHis: 2.121 ± 0.016	6.832LeuIle: 6.832 ± 0.032	7.616LeuLys: 7.616 ± 0.038	8.528LeuLeu: 8.528 ± 0.042	1.935LeuMet: 1.935 ± 0.014	6.176LeuAsn: 6.176 ± 0.037	3.917LeuPro: 3.917 ± 0.023	3.807LeuGln: 3.807 ± 0.025	4.384LeuArg: 4.384 ± 0.026	7.246LeuSer: 7.246 ± 0.036	5.042LeuThr: 5.042 ± 0.029	4.692LeuVal: 4.692 ± 0.027	1.017LeuTrp: 1.017 ± 0.01	3.588LeuTyr: 3.588 ± 0.022	0.0LeuXaa: 0.0 ± 0.0
Met	1.24MetAla: 1.24 ± 0.011	0.289MetCys: 0.289 ± 0.005	1.151MetAsp: 1.151 ± 0.011	1.28MetGlu: 1.28 ± 0.014	0.838MetPhe: 0.838 ± 0.009	0.937MetGly: 0.937 ± 0.014	0.41MetHis: 0.41 ± 0.007	1.614MetIle: 1.614 ± 0.013	1.612MetLys: 1.612 ± 0.014	1.741MetLeu: 1.741 ± 0.016	0.547MetMet: 0.547 ± 0.009	1.408MetAsn: 1.408 ± 0.014	0.862MetPro: 0.862 ± 0.009	0.761MetGln: 0.761 ± 0.009	0.818MetArg: 0.818 ± 0.011	1.715MetSer: 1.715 ± 0.014	1.196MetThr: 1.196 ± 0.011	1.103MetVal: 1.103 ± 0.011	0.234MetTrp: 0.234 ± 0.006	0.636MetTyr: 0.636 ± 0.008	0.0MetXaa: 0.0 ± 0.0
Asn	3.139AsnAla: 3.139 ± 0.023	1.036AsnCys: 1.036 ± 0.012	4.163AsnAsp: 4.163 ± 0.026	4.811AsnGlu: 4.811 ± 0.027	3.134AsnPhe: 3.134 ± 0.023	3.055AsnGly: 3.055 ± 0.026	1.344AsnHis: 1.344 ± 0.011	5.918AsnIle: 5.918 ± 0.026	5.041AsnLys: 5.041 ± 0.03	6.416AsnLeu: 6.416 ± 0.035	1.341AsnMet: 1.341 ± 0.012	6.038AsnAsn: 6.038 ± 0.051	2.636AsnPro: 2.636 ± 0.019	2.53AsnGln: 2.53 ± 0.017	2.522AsnArg: 2.522 ± 0.021	5.489AsnSer: 5.489 ± 0.032	3.607AsnThr: 3.607 ± 0.026	3.425AsnVal: 3.425 ± 0.02	0.718AsnTrp: 0.718 ± 0.008	2.692AsnTyr: 2.692 ± 0.019	0.0AsnXaa: 0.0 ± 0.0
Pro	1.599ProAla: 1.599 ± 0.017	0.511ProCys: 0.511 ± 0.007	2.21ProAsp: 2.21 ± 0.019	2.818ProGlu: 2.818 ± 0.019	1.89ProPhe: 1.89 ± 0.015	1.63ProGly: 1.63 ± 0.015	0.817ProHis: 0.817 ± 0.011	3.136ProIle: 3.136 ± 0.021	2.719ProLys: 2.719 ± 0.019	3.311ProLeu: 3.311 ± 0.022	0.679ProMet: 0.679 ± 0.009	2.856ProAsn: 2.856 ± 0.019	2.296ProPro: 2.296 ± 0.032	1.538ProGln: 1.538 ± 0.016	1.477ProArg: 1.477 ± 0.014	3.346ProSer: 3.346 ± 0.023	2.572ProThr: 2.572 ± 0.021	1.969ProVal: 1.969 ± 0.017	0.41ProTrp: 0.41 ± 0.007	1.658ProTyr: 1.658 ± 0.013	0.0ProXaa: 0.0 ± 0.0
Gln	1.669GlnAla: 1.669 ± 0.014	0.617GlnCys: 0.617 ± 0.009	1.911GlnAsp: 1.911 ± 0.015	2.673GlnGlu: 2.673 ± 0.02	1.72GlnPhe: 1.72 ± 0.013	1.364GlnGly: 1.364 ± 0.013	0.862GlnHis: 0.862 ± 0.012	3.154GlnIle: 3.154 ± 0.022	3.103GlnLys: 3.103 ± 0.024	3.43GlnLeu: 3.43 ± 0.02	0.811GlnMet: 0.811 ± 0.01	2.808GlnAsn: 2.808 ± 0.017	1.422GlnPro: 1.422 ± 0.016	1.969GlnGln: 1.969 ± 0.025	1.75GlnArg: 1.75 ± 0.016	2.622GlnSer: 2.622 ± 0.023	1.968GlnThr: 1.968 ± 0.017	1.763GlnVal: 1.763 ± 0.014	0.424GlnTrp: 0.424 ± 0.006	1.577GlnTyr: 1.577 ± 0.015	0.0GlnXaa: 0.0 ± 0.0
Arg	1.924ArgAla: 1.924 ± 0.016	0.709ArgCys: 0.709 ± 0.009	2.254ArgAsp: 2.254 ± 0.018	2.738ArgGlu: 2.738 ± 0.021	1.869ArgPhe: 1.869 ± 0.017	2.025ArgGly: 2.025 ± 0.022	0.98ArgHis: 0.98 ± 0.011	3.363ArgIle: 3.363 ± 0.019	3.69ArgLys: 3.69 ± 0.025	3.798ArgLeu: 3.798 ± 0.02	0.899ArgMet: 0.899 ± 0.01	2.781ArgAsn: 2.781 ± 0.021	1.922ArgPro: 1.922 ± 0.014	1.648ArgGln: 1.648 ± 0.015	2.425ArgArg: 2.425 ± 0.022	3.087ArgSer: 3.087 ± 0.022	2.111ArgThr: 2.111 ± 0.017	2.05ArgVal: 2.05 ± 0.015	0.496ArgTrp: 0.496 ± 0.007	1.772ArgTyr: 1.772 ± 0.018	0.0ArgXaa: 0.0 ± 0.0
Ser	3.486SerAla: 3.486 ± 0.021	1.163SerCys: 1.163 ± 0.012	4.586SerAsp: 4.586 ± 0.024	4.919SerGlu: 4.919 ± 0.028	3.716SerPhe: 3.716 ± 0.022	3.578SerGly: 3.578 ± 0.024	1.596SerHis: 1.596 ± 0.013	5.795SerIle: 5.795 ± 0.029	5.679SerLys: 5.679 ± 0.03	7.527SerLeu: 7.527 ± 0.046	1.431SerMet: 1.431 ± 0.013	5.42SerAsn: 5.42 ± 0.029	2.994SerPro: 2.994 ± 0.029	3.079SerGln: 3.079 ± 0.021	3.316SerArg: 3.316 ± 0.024	7.504SerSer: 7.504 ± 0.05	4.924SerThr: 4.924 ± 0.029	3.654SerVal: 3.654 ± 0.023	0.855SerTrp: 0.855 ± 0.01	2.755SerTyr: 2.755 ± 0.018	0.0SerXaa: 0.0 ± 0.0
Thr	2.583ThrAla: 2.583 ± 0.021	0.892ThrCys: 0.892 ± 0.01	2.613ThrAsp: 2.613 ± 0.017	2.987ThrGlu: 2.987 ± 0.019	2.67ThrPhe: 2.67 ± 0.018	2.392ThrGly: 2.392 ± 0.018	1.04ThrHis: 1.04 ± 0.011	4.439ThrIle: 4.439 ± 0.024	3.939ThrLys: 3.939 ± 0.023	5.411ThrLeu: 5.411 ± 0.034	0.984ThrMet: 0.984 ± 0.011	3.683ThrAsn: 3.683 ± 0.02	2.565ThrPro: 2.565 ± 0.021	2.019ThrGln: 2.019 ± 0.016	2.174ThrArg: 2.174 ± 0.017	5.025ThrSer: 5.025 ± 0.034	3.782ThrThr: 3.782 ± 0.036	2.685ThrVal: 2.685 ± 0.018	0.702ThrTrp: 0.702 ± 0.008	2.095ThrTyr: 2.095 ± 0.014	0.0ThrXaa: 0.0 ± 0.0
Val	2.689ValAla: 2.689 ± 0.018	0.8ValCys: 0.8 ± 0.009	2.975ValAsp: 2.975 ± 0.021	3.455ValGlu: 3.455 ± 0.026	2.357ValPhe: 2.357 ± 0.017	2.499ValGly: 2.499 ± 0.02	1.128ValHis: 1.128 ± 0.013	4.127ValIle: 4.127 ± 0.023	3.762ValLys: 3.762 ± 0.022	4.713ValLeu: 4.713 ± 0.024	1.039ValMet: 1.039 ± 0.011	3.142ValAsn: 3.142 ± 0.018	2.038ValPro: 2.038 ± 0.017	1.756ValGln: 1.756 ± 0.015	1.953ValArg: 1.953 ± 0.017	3.606ValSer: 3.606 ± 0.021	2.809ValThr: 2.809 ± 0.02	2.987ValVal: 2.987 ± 0.027	0.532ValTrp: 0.532 ± 0.008	1.94ValTyr: 1.94 ± 0.014	0.0ValXaa: 0.0 ± 0.0
Trp	0.518TrpAla: 0.518 ± 0.007	0.32TrpCys: 0.32 ± 0.006	0.727TrpAsp: 0.727 ± 0.009	0.772TrpGlu: 0.772 ± 0.009	0.503TrpPhe: 0.503 ± 0.007	0.531TrpGly: 0.531 ± 0.008	0.269TrpHis: 0.269 ± 0.005	0.99TrpIle: 0.99 ± 0.011	0.987TrpLys: 0.987 ± 0.011	1.011TrpLeu: 1.011 ± 0.011	0.266TrpMet: 0.266 ± 0.006	0.898TrpAsn: 0.898 ± 0.011	0.337TrpPro: 0.337 ± 0.006	0.417TrpGln: 0.417 ± 0.006	0.517TrpArg: 0.517 ± 0.008	0.828TrpSer: 0.828 ± 0.01	0.646TrpThr: 0.646 ± 0.008	0.575TrpVal: 0.575 ± 0.008	0.152TrpTrp: 0.152 ± 0.005	0.414TrpTyr: 0.414 ± 0.007	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.703TyrAla: 1.703 ± 0.014	0.836TyrCys: 0.836 ± 0.011	2.254TyrAsp: 2.254 ± 0.018	2.559TyrGlu: 2.559 ± 0.022	2.081TyrPhe: 2.081 ± 0.019	2.09TyrGly: 2.09 ± 0.018	0.98TyrHis: 0.98 ± 0.011	3.155TyrIle: 3.155 ± 0.022	2.845TyrLys: 2.845 ± 0.02	3.916TyrLeu: 3.916 ± 0.025	0.882TyrMet: 0.882 ± 0.01	2.776TyrAsn: 2.776 ± 0.019	1.41TyrPro: 1.41 ± 0.014	1.645TyrGln: 1.645 ± 0.014	1.746TyrArg: 1.746 ± 0.016	2.955TyrSer: 2.955 ± 0.019	1.973TyrThr: 1.973 ± 0.014	1.948TyrVal: 1.948 ± 0.015	0.473TyrTrp: 0.473 ± 0.007	1.919TyrTyr: 1.919 ± 0.02	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 31020 proteins (9364735 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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