Amino acid dipepetide frequency for Tarumizu tick virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.412AlaAla: 4.412 ± 0.755
0.84AlaCys: 0.84 ± 0.299
3.362AlaAsp: 3.362 ± 0.745
3.152AlaGlu: 3.152 ± 0.502
2.626AlaPhe: 2.626 ± 0.478
5.253AlaGly: 5.253 ± 0.651
1.471AlaHis: 1.471 ± 0.502
3.047AlaIle: 3.047 ± 0.501
2.626AlaLys: 2.626 ± 0.341
7.144AlaLeu: 7.144 ± 0.795
2.311AlaMet: 2.311 ± 0.34
1.786AlaAsn: 1.786 ± 0.39
3.572AlaPro: 3.572 ± 1.049
1.051AlaGln: 1.051 ± 0.277
5.043AlaArg: 5.043 ± 0.754
5.253AlaSer: 5.253 ± 0.986
3.992AlaThr: 3.992 ± 0.844
6.093AlaVal: 6.093 ± 0.584
0.315AlaTrp: 0.315 ± 0.191
2.311AlaTyr: 2.311 ± 0.459
0.0AlaXaa: 0.0 ± 0.0
Cys
0.945CysAla: 0.945 ± 0.298
0.84CysCys: 0.84 ± 0.208
0.735CysAsp: 0.735 ± 0.226
1.261CysGlu: 1.261 ± 0.414
0.945CysPhe: 0.945 ± 0.265
2.521CysGly: 2.521 ± 0.462
0.525CysHis: 0.525 ± 0.155
0.84CysIle: 0.84 ± 0.346
0.735CysLys: 0.735 ± 0.255
0.945CysLeu: 0.945 ± 0.27
0.735CysMet: 0.735 ± 0.255
0.315CysAsn: 0.315 ± 0.179
0.525CysPro: 0.525 ± 0.199
0.735CysGln: 0.735 ± 0.222
1.051CysArg: 1.051 ± 0.26
0.945CysSer: 0.945 ± 0.234
0.84CysThr: 0.84 ± 0.233
1.471CysVal: 1.471 ± 0.366
0.42CysTrp: 0.42 ± 0.253
0.84CysTyr: 0.84 ± 0.231
0.105CysXaa: 0.105 ± 0.126
Asp
3.677AspAla: 3.677 ± 0.656
1.681AspCys: 1.681 ± 0.484
3.257AspAsp: 3.257 ± 0.633
4.097AspGlu: 4.097 ± 0.831
1.891AspPhe: 1.891 ± 0.469
4.937AspGly: 4.937 ± 0.489
1.156AspHis: 1.156 ± 0.451
2.941AspIle: 2.941 ± 0.436
2.416AspLys: 2.416 ± 0.627
5.988AspLeu: 5.988 ± 0.679
1.786AspMet: 1.786 ± 0.442
1.681AspAsn: 1.681 ± 0.521
2.521AspPro: 2.521 ± 0.587
1.996AspGln: 1.996 ± 0.345
3.887AspArg: 3.887 ± 0.645
3.362AspSer: 3.362 ± 0.711
1.891AspThr: 1.891 ± 0.405
6.723AspVal: 6.723 ± 0.703
1.681AspTrp: 1.681 ± 0.599
2.206AspTyr: 2.206 ± 0.565
0.0AspXaa: 0.0 ± 0.0
Glu
4.412GluAla: 4.412 ± 0.624
1.051GluCys: 1.051 ± 0.374
3.572GluAsp: 3.572 ± 0.325
2.836GluGlu: 2.836 ± 0.521
2.626GluPhe: 2.626 ± 0.596
3.992GluGly: 3.992 ± 0.75
1.471GluHis: 1.471 ± 0.492
3.572GluIle: 3.572 ± 0.562
4.202GluLys: 4.202 ± 0.853
4.517GluLeu: 4.517 ± 0.841
2.311GluMet: 2.311 ± 0.315
1.786GluAsn: 1.786 ± 0.385
1.786GluPro: 1.786 ± 0.256
1.996GluGln: 1.996 ± 0.344
4.307GluArg: 4.307 ± 0.694
2.416GluSer: 2.416 ± 0.527
2.521GluThr: 2.521 ± 0.482
4.832GluVal: 4.832 ± 0.578
1.681GluTrp: 1.681 ± 0.367
2.206GluTyr: 2.206 ± 0.6
0.0GluXaa: 0.0 ± 0.0
Phe
2.311PheAla: 2.311 ± 0.427
0.84PheCys: 0.84 ± 0.251
3.362PheAsp: 3.362 ± 0.528
2.206PheGlu: 2.206 ± 0.455
1.891PhePhe: 1.891 ± 0.301
3.677PheGly: 3.677 ± 0.596
1.471PheHis: 1.471 ± 0.375
2.731PheIle: 2.731 ± 0.606
0.735PheLys: 0.735 ± 0.278
3.362PheLeu: 3.362 ± 0.504
0.945PheMet: 0.945 ± 0.22
2.311PheAsn: 2.311 ± 0.359
2.311PhePro: 2.311 ± 0.511
1.786PheGln: 1.786 ± 0.437
3.572PheArg: 3.572 ± 0.629
4.832PheSer: 4.832 ± 1.046
2.206PheThr: 2.206 ± 0.444
2.521PheVal: 2.521 ± 0.211
0.21PheTrp: 0.21 ± 0.17
1.681PheTyr: 1.681 ± 0.456
0.0PheXaa: 0.0 ± 0.0
Gly
5.778GlyAla: 5.778 ± 0.981
1.366GlyCys: 1.366 ± 0.426
4.727GlyAsp: 4.727 ± 0.297
3.992GlyGlu: 3.992 ± 0.611
2.626GlyPhe: 2.626 ± 0.535
4.307GlyGly: 4.307 ± 0.931
1.156GlyHis: 1.156 ± 0.354
3.572GlyIle: 3.572 ± 0.725
2.311GlyLys: 2.311 ± 0.655
7.039GlyLeu: 7.039 ± 0.615
2.731GlyMet: 2.731 ± 0.53
2.626GlyAsn: 2.626 ± 0.416
3.047GlyPro: 3.047 ± 0.657
2.626GlyGln: 2.626 ± 0.464
5.463GlyArg: 5.463 ± 0.753
5.673GlySer: 5.673 ± 1.165
4.412GlyThr: 4.412 ± 0.485
7.354GlyVal: 7.354 ± 0.887
1.891GlyTrp: 1.891 ± 0.334
2.521GlyTyr: 2.521 ± 0.619
0.0GlyXaa: 0.0 ± 0.0
His
1.366HisAla: 1.366 ± 0.261
0.42HisCys: 0.42 ± 0.157
1.786HisAsp: 1.786 ± 0.338
1.051HisGlu: 1.051 ± 0.371
1.261HisPhe: 1.261 ± 0.358
1.366HisGly: 1.366 ± 0.416
1.156HisHis: 1.156 ± 0.353
1.051HisIle: 1.051 ± 0.415
0.42HisLys: 0.42 ± 0.176
1.786HisLeu: 1.786 ± 0.411
0.42HisMet: 0.42 ± 0.223
0.735HisAsn: 0.735 ± 0.23
0.63HisPro: 0.63 ± 0.211
1.576HisGln: 1.576 ± 0.29
1.051HisArg: 1.051 ± 0.388
1.786HisSer: 1.786 ± 0.518
1.786HisThr: 1.786 ± 0.332
3.152HisVal: 3.152 ± 0.669
0.525HisTrp: 0.525 ± 0.193
1.576HisTyr: 1.576 ± 0.573
0.0HisXaa: 0.0 ± 0.0
Ile
2.101IleAla: 2.101 ± 0.394
1.051IleCys: 1.051 ± 0.278
3.467IleAsp: 3.467 ± 0.61
3.362IleGlu: 3.362 ± 0.677
1.891IlePhe: 1.891 ± 0.385
3.572IleGly: 3.572 ± 0.765
1.681IleHis: 1.681 ± 0.34
1.051IleIle: 1.051 ± 0.414
2.206IleLys: 2.206 ± 0.428
4.517IleLeu: 4.517 ± 0.762
1.051IleMet: 1.051 ± 0.263
2.311IleAsn: 2.311 ± 0.351
2.416IlePro: 2.416 ± 0.472
1.786IleGln: 1.786 ± 0.487
4.097IleArg: 4.097 ± 1.028
3.572IleSer: 3.572 ± 0.517
2.626IleThr: 2.626 ± 0.433
4.727IleVal: 4.727 ± 0.779
0.735IleTrp: 0.735 ± 0.206
1.996IleTyr: 1.996 ± 0.277
0.0IleXaa: 0.0 ± 0.0
Lys
3.572LysAla: 3.572 ± 0.861
0.21LysCys: 0.21 ± 0.141
2.311LysAsp: 2.311 ± 0.428
3.047LysGlu: 3.047 ± 0.511
1.576LysPhe: 1.576 ± 0.542
2.311LysGly: 2.311 ± 0.34
1.471LysHis: 1.471 ± 0.462
2.836LysIle: 2.836 ± 0.495
2.626LysLys: 2.626 ± 0.761
3.677LysLeu: 3.677 ± 0.492
0.945LysMet: 0.945 ± 0.272
1.156LysAsn: 1.156 ± 0.342
1.156LysPro: 1.156 ± 0.239
1.576LysGln: 1.576 ± 0.531
3.047LysArg: 3.047 ± 0.811
2.311LysSer: 2.311 ± 0.394
1.681LysThr: 1.681 ± 0.446
2.626LysVal: 2.626 ± 0.643
0.735LysTrp: 0.735 ± 0.316
1.051LysTyr: 1.051 ± 0.353
0.0LysXaa: 0.0 ± 0.0
Leu
4.937LeuAla: 4.937 ± 0.717
1.471LeuCys: 1.471 ± 0.396
6.408LeuAsp: 6.408 ± 0.737
5.043LeuGlu: 5.043 ± 0.581
4.622LeuPhe: 4.622 ± 0.91
6.934LeuGly: 6.934 ± 0.779
1.891LeuHis: 1.891 ± 0.56
4.517LeuIle: 4.517 ± 0.655
3.992LeuLys: 3.992 ± 0.715
9.56LeuLeu: 9.56 ± 1.135
1.996LeuMet: 1.996 ± 0.405
5.463LeuAsn: 5.463 ± 0.809
5.043LeuPro: 5.043 ± 0.603
2.731LeuGln: 2.731 ± 0.484
6.303LeuArg: 6.303 ± 0.941
8.404LeuSer: 8.404 ± 1.182
4.412LeuThr: 4.412 ± 0.883
5.883LeuVal: 5.883 ± 0.534
1.471LeuTrp: 1.471 ± 0.212
2.731LeuTyr: 2.731 ± 0.684
0.0LeuXaa: 0.0 ± 0.0
Met
2.626MetAla: 2.626 ± 0.832
1.051MetCys: 1.051 ± 0.317
1.996MetAsp: 1.996 ± 0.384
1.366MetGlu: 1.366 ± 0.427
1.576MetPhe: 1.576 ± 0.285
1.051MetGly: 1.051 ± 0.307
0.42MetHis: 0.42 ± 0.256
1.786MetIle: 1.786 ± 0.358
1.156MetLys: 1.156 ± 0.333
2.731MetLeu: 2.731 ± 0.494
1.051MetMet: 1.051 ± 0.462
1.681MetAsn: 1.681 ± 0.482
1.156MetPro: 1.156 ± 0.415
0.63MetGln: 0.63 ± 0.163
2.101MetArg: 2.101 ± 0.226
1.261MetSer: 1.261 ± 0.42
1.576MetThr: 1.576 ± 0.296
1.471MetVal: 1.471 ± 0.417
0.0MetTrp: 0.0 ± 0.0
1.261MetTyr: 1.261 ± 0.199
0.0MetXaa: 0.0 ± 0.0
Asn
2.521AsnAla: 2.521 ± 0.668
0.315AsnCys: 0.315 ± 0.149
2.941AsnAsp: 2.941 ± 0.534
2.311AsnGlu: 2.311 ± 0.377
1.786AsnPhe: 1.786 ± 0.414
2.941AsnGly: 2.941 ± 0.906
1.156AsnHis: 1.156 ± 0.221
2.836AsnIle: 2.836 ± 0.469
0.735AsnLys: 0.735 ± 0.279
4.307AsnLeu: 4.307 ± 0.792
1.261AsnMet: 1.261 ± 0.345
0.84AsnAsn: 0.84 ± 0.39
1.681AsnPro: 1.681 ± 0.437
1.051AsnGln: 1.051 ± 0.286
1.681AsnArg: 1.681 ± 0.371
1.471AsnSer: 1.471 ± 0.567
0.945AsnThr: 0.945 ± 0.182
5.673AsnVal: 5.673 ± 0.784
0.525AsnTrp: 0.525 ± 0.209
1.576AsnTyr: 1.576 ± 0.374
0.0AsnXaa: 0.0 ± 0.0
Pro
3.467ProAla: 3.467 ± 1.318
1.051ProCys: 1.051 ± 0.376
2.206ProAsp: 2.206 ± 0.266
3.047ProGlu: 3.047 ± 0.384
2.101ProPhe: 2.101 ± 0.538
3.047ProGly: 3.047 ± 0.444
0.84ProHis: 0.84 ± 0.358
1.681ProIle: 1.681 ± 0.356
2.101ProLys: 2.101 ± 0.683
4.517ProLeu: 4.517 ± 0.71
0.735ProMet: 0.735 ± 0.265
2.731ProAsn: 2.731 ± 0.507
3.152ProPro: 3.152 ± 1.367
1.786ProGln: 1.786 ± 0.242
3.782ProArg: 3.782 ± 0.505
2.521ProSer: 2.521 ± 0.525
1.996ProThr: 1.996 ± 0.494
3.257ProVal: 3.257 ± 0.591
0.63ProTrp: 0.63 ± 0.236
1.996ProTyr: 1.996 ± 0.467
0.0ProXaa: 0.0 ± 0.0
Gln
3.152GlnAla: 3.152 ± 0.593
0.42GlnCys: 0.42 ± 0.186
1.471GlnAsp: 1.471 ± 0.346
1.681GlnGlu: 1.681 ± 0.371
2.206GlnPhe: 2.206 ± 0.703
2.626GlnGly: 2.626 ± 0.436
0.945GlnHis: 0.945 ± 0.307
1.366GlnIle: 1.366 ± 0.45
1.471GlnLys: 1.471 ± 0.568
3.887GlnLeu: 3.887 ± 0.718
1.156GlnMet: 1.156 ± 0.386
0.84GlnAsn: 0.84 ± 0.299
1.366GlnPro: 1.366 ± 0.517
1.051GlnGln: 1.051 ± 0.36
1.996GlnArg: 1.996 ± 0.338
1.786GlnSer: 1.786 ± 0.513
0.945GlnThr: 0.945 ± 0.352
2.731GlnVal: 2.731 ± 0.531
0.315GlnTrp: 0.315 ± 0.187
1.366GlnTyr: 1.366 ± 0.387
0.0GlnXaa: 0.0 ± 0.0
Arg
5.043ArgAla: 5.043 ± 0.635
0.84ArgCys: 0.84 ± 0.326
3.992ArgAsp: 3.992 ± 0.505
5.148ArgGlu: 5.148 ± 0.779
3.152ArgPhe: 3.152 ± 0.351
5.358ArgGly: 5.358 ± 0.548
1.996ArgHis: 1.996 ± 0.482
3.677ArgIle: 3.677 ± 0.722
1.891ArgLys: 1.891 ± 0.545
6.093ArgLeu: 6.093 ± 1.404
2.521ArgMet: 2.521 ± 0.416
1.786ArgAsn: 1.786 ± 0.446
2.941ArgPro: 2.941 ± 0.586
2.941ArgGln: 2.941 ± 0.473
6.303ArgArg: 6.303 ± 1.3
5.148ArgSer: 5.148 ± 1.144
2.626ArgThr: 2.626 ± 0.47
7.879ArgVal: 7.879 ± 1.331
1.576ArgTrp: 1.576 ± 0.588
2.521ArgTyr: 2.521 ± 0.415
0.0ArgXaa: 0.0 ± 0.0
Ser
4.517SerAla: 4.517 ± 0.77
1.576SerCys: 1.576 ± 0.266
3.572SerAsp: 3.572 ± 0.842
3.887SerGlu: 3.887 ± 0.589
3.257SerPhe: 3.257 ± 0.803
5.988SerGly: 5.988 ± 1.352
1.576SerHis: 1.576 ± 0.292
2.836SerIle: 2.836 ± 0.523
3.362SerLys: 3.362 ± 0.659
6.093SerLeu: 6.093 ± 0.915
1.576SerMet: 1.576 ± 0.325
2.521SerAsn: 2.521 ± 0.639
3.572SerPro: 3.572 ± 0.661
1.996SerGln: 1.996 ± 0.494
5.253SerArg: 5.253 ± 0.634
4.832SerSer: 4.832 ± 0.992
3.467SerThr: 3.467 ± 0.614
4.517SerVal: 4.517 ± 0.873
1.366SerTrp: 1.366 ± 0.361
1.996SerTyr: 1.996 ± 0.414
0.0SerXaa: 0.0 ± 0.0
Thr
2.941ThrAla: 2.941 ± 0.391
0.84ThrCys: 0.84 ± 0.232
1.681ThrAsp: 1.681 ± 0.514
2.101ThrGlu: 2.101 ± 0.312
2.941ThrPhe: 2.941 ± 0.642
3.467ThrGly: 3.467 ± 0.832
0.945ThrHis: 0.945 ± 0.241
2.521ThrIle: 2.521 ± 0.338
1.996ThrLys: 1.996 ± 0.372
4.202ThrLeu: 4.202 ± 0.78
0.525ThrMet: 0.525 ± 0.188
2.206ThrAsn: 2.206 ± 0.45
2.521ThrPro: 2.521 ± 0.392
1.051ThrGln: 1.051 ± 0.332
3.257ThrArg: 3.257 ± 0.583
3.047ThrSer: 3.047 ± 0.738
2.311ThrThr: 2.311 ± 0.525
4.307ThrVal: 4.307 ± 1.053
0.63ThrTrp: 0.63 ± 0.39
1.681ThrTyr: 1.681 ± 0.441
0.0ThrXaa: 0.0 ± 0.0
Val
4.832ValAla: 4.832 ± 0.909
1.471ValCys: 1.471 ± 0.262
5.358ValAsp: 5.358 ± 0.577
5.043ValGlu: 5.043 ± 0.776
3.467ValPhe: 3.467 ± 0.744
6.934ValGly: 6.934 ± 1.103
1.786ValHis: 1.786 ± 0.452
4.517ValIle: 4.517 ± 0.587
3.152ValLys: 3.152 ± 0.64
6.513ValLeu: 6.513 ± 0.624
2.626ValMet: 2.626 ± 0.456
3.257ValAsn: 3.257 ± 0.607
5.148ValPro: 5.148 ± 0.907
2.836ValGln: 2.836 ± 0.477
7.984ValArg: 7.984 ± 0.959
7.144ValSer: 7.144 ± 1.132
2.836ValThr: 2.836 ± 0.705
6.303ValVal: 6.303 ± 1.123
0.945ValTrp: 0.945 ± 0.383
2.731ValTyr: 2.731 ± 0.387
0.0ValXaa: 0.0 ± 0.0
Trp
1.051TrpAla: 1.051 ± 0.457
0.315TrpCys: 0.315 ± 0.198
0.21TrpAsp: 0.21 ± 0.11
0.945TrpGlu: 0.945 ± 0.353
1.156TrpPhe: 1.156 ± 0.381
0.945TrpGly: 0.945 ± 0.242
0.42TrpHis: 0.42 ± 0.229
0.735TrpIle: 0.735 ± 0.174
0.735TrpLys: 0.735 ± 0.306
2.731TrpLeu: 2.731 ± 0.409
0.315TrpMet: 0.315 ± 0.175
0.84TrpAsn: 0.84 ± 0.208
0.21TrpPro: 0.21 ± 0.156
0.525TrpGln: 0.525 ± 0.304
1.156TrpArg: 1.156 ± 0.295
0.315TrpSer: 0.315 ± 0.175
1.051TrpThr: 1.051 ± 0.381
1.471TrpVal: 1.471 ± 0.461
0.315TrpTrp: 0.315 ± 0.135
0.525TrpTyr: 0.525 ± 0.214
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.996TyrAla: 1.996 ± 0.352
0.63TyrCys: 0.63 ± 0.264
3.362TyrAsp: 3.362 ± 0.655
2.626TyrGlu: 2.626 ± 0.561
1.366TyrPhe: 1.366 ± 0.319
3.992TyrGly: 3.992 ± 0.331
1.366TyrHis: 1.366 ± 0.325
2.101TyrIle: 2.101 ± 0.364
1.051TyrLys: 1.051 ± 0.311
4.202TyrLeu: 4.202 ± 0.674
0.84TyrMet: 0.84 ± 0.384
1.681TyrAsn: 1.681 ± 0.403
1.891TyrPro: 1.891 ± 0.312
1.051TyrGln: 1.051 ± 0.468
1.996TyrArg: 1.996 ± 0.509
1.681TyrSer: 1.681 ± 0.4
1.051TyrThr: 1.051 ± 0.27
1.891TyrVal: 1.891 ± 0.335
0.0TyrTrp: 0.0 ± 0.0
1.156TyrTyr: 1.156 ± 0.327
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.105XaaArg: 0.105 ± 0.126
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 13 proteins (9520 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski