Hepatitis delta virus genotype I (isolate D380) (HDV)

Taxonomy: Viruses; Ribozyviria; Kolmioviridae; Deltavirus; Hepatitis delta virus

Average proteome isoelectric point is 8.98

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 2 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>sp|P29996|LHDAG_HDVD3 Large delta antigen OS=Hepatitis delta virus genotype I (isolate D380) OX=31762 PE=1 SV=2
MM1 pKa = 7.36SRR3 pKa = 11.84PEE5 pKa = 3.74GRR7 pKa = 11.84KK8 pKa = 9.03NRR10 pKa = 11.84GGRR13 pKa = 11.84EE14 pKa = 3.73EE15 pKa = 5.35VLEE18 pKa = 3.94QWVSGRR24 pKa = 11.84KK25 pKa = 9.34KK26 pKa = 10.71LEE28 pKa = 3.65EE29 pKa = 4.23LEE31 pKa = 4.03RR32 pKa = 11.84DD33 pKa = 3.22LRR35 pKa = 11.84KK36 pKa = 10.05VKK38 pKa = 10.64KK39 pKa = 10.03KK40 pKa = 9.97IKK42 pKa = 9.91KK43 pKa = 10.45LEE45 pKa = 4.66DD46 pKa = 3.07EE47 pKa = 4.91HH48 pKa = 6.94PWLGNIKK55 pKa = 10.42GILGKK60 pKa = 9.81KK61 pKa = 10.25DD62 pKa = 3.26KK63 pKa = 10.57DD64 pKa = 3.88GEE66 pKa = 4.39GAPPAKK72 pKa = 9.95RR73 pKa = 11.84ARR75 pKa = 11.84TDD77 pKa = 3.15QMEE80 pKa = 4.43VDD82 pKa = 3.25SGPRR86 pKa = 11.84KK87 pKa = 9.37RR88 pKa = 11.84PSRR91 pKa = 11.84GGFTDD96 pKa = 4.94KK97 pKa = 10.54EE98 pKa = 4.37RR99 pKa = 11.84QDD101 pKa = 3.13HH102 pKa = 6.0RR103 pKa = 11.84RR104 pKa = 11.84RR105 pKa = 11.84KK106 pKa = 9.67ALEE109 pKa = 3.81NKK111 pKa = 9.78RR112 pKa = 11.84KK113 pKa = 9.22QLSAGGKK120 pKa = 8.27NLSKK124 pKa = 10.99EE125 pKa = 4.15EE126 pKa = 3.97EE127 pKa = 4.15EE128 pKa = 4.01EE129 pKa = 3.96LRR131 pKa = 11.84RR132 pKa = 11.84LTEE135 pKa = 3.65EE136 pKa = 3.73DD137 pKa = 2.96EE138 pKa = 4.07RR139 pKa = 11.84RR140 pKa = 11.84EE141 pKa = 3.83RR142 pKa = 11.84RR143 pKa = 11.84IAGPQVGGVNPLEE156 pKa = 4.81GGTRR160 pKa = 11.84GAPGGGFVPSMQGVPEE176 pKa = 4.31SPFTRR181 pKa = 11.84TGEE184 pKa = 4.06GLDD187 pKa = 3.3IRR189 pKa = 11.84GSQGFPWDD197 pKa = 3.45ILFPADD203 pKa = 4.47PPSSPQSCRR212 pKa = 11.84PQQ214 pKa = 3.48

Molecular weight: 24.06 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>sp|P29996|LHDAG_HDVD3 Large delta antigen OS=Hepatitis delta virus genotype I (isolate D380) OX=31762 PE=1 SV=2
MM1 pKa = 7.36SRR3 pKa = 11.84PEE5 pKa = 3.74GRR7 pKa = 11.84KK8 pKa = 9.03NRR10 pKa = 11.84GGRR13 pKa = 11.84EE14 pKa = 3.73EE15 pKa = 5.35VLEE18 pKa = 3.94QWVSGRR24 pKa = 11.84KK25 pKa = 9.34KK26 pKa = 10.71LEE28 pKa = 3.65EE29 pKa = 4.23LEE31 pKa = 4.03RR32 pKa = 11.84DD33 pKa = 3.22LRR35 pKa = 11.84KK36 pKa = 10.05VKK38 pKa = 10.64KK39 pKa = 10.03KK40 pKa = 9.97IKK42 pKa = 9.91KK43 pKa = 10.45LEE45 pKa = 4.66DD46 pKa = 3.07EE47 pKa = 4.91HH48 pKa = 6.94PWLGNIKK55 pKa = 10.42GILGKK60 pKa = 9.81KK61 pKa = 10.25DD62 pKa = 3.26KK63 pKa = 10.57DD64 pKa = 3.88GEE66 pKa = 4.39GAPPAKK72 pKa = 9.95RR73 pKa = 11.84ARR75 pKa = 11.84TDD77 pKa = 3.15QMEE80 pKa = 4.43VDD82 pKa = 3.25SGPRR86 pKa = 11.84KK87 pKa = 9.37RR88 pKa = 11.84PSRR91 pKa = 11.84GGFTDD96 pKa = 4.94KK97 pKa = 10.54EE98 pKa = 4.37RR99 pKa = 11.84QDD101 pKa = 3.13HH102 pKa = 6.0RR103 pKa = 11.84RR104 pKa = 11.84RR105 pKa = 11.84KK106 pKa = 9.67ALEE109 pKa = 3.81NKK111 pKa = 9.78RR112 pKa = 11.84KK113 pKa = 9.22QLSAGGKK120 pKa = 8.27NLSKK124 pKa = 10.99EE125 pKa = 4.15EE126 pKa = 3.97EE127 pKa = 4.15EE128 pKa = 4.01EE129 pKa = 3.96LRR131 pKa = 11.84RR132 pKa = 11.84LTEE135 pKa = 3.65EE136 pKa = 3.73DD137 pKa = 2.96EE138 pKa = 4.07RR139 pKa = 11.84RR140 pKa = 11.84EE141 pKa = 3.83RR142 pKa = 11.84RR143 pKa = 11.84IAGPQVGGVNPLEE156 pKa = 4.81GGTRR160 pKa = 11.84GAPGGGFVPSMQGVPEE176 pKa = 4.31SPFTRR181 pKa = 11.84TGEE184 pKa = 4.06GLDD187 pKa = 3.3IRR189 pKa = 11.84GSQGFPP195 pKa = 3.1

Molecular weight: 21.94 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

2

0

2

409

195

214

204.5

23.0

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

3.667 ± 0.05

0.244 ± 0.157

5.379 ± 0.161

12.225 ± 0.382

2.2 ± 0.096

13.692 ± 0.428

0.978 ± 0.031

2.689 ± 0.08

10.269 ± 0.321

7.09 ± 0.057

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.467 ± 0.046

2.445 ± 0.076

7.579 ± 0.586

3.912 ± 0.207

12.958 ± 0.241

5.134 ± 0.333

2.934 ± 0.092

3.912 ± 0.122

1.222 ± 0.126

0.0 ± 0.0
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski