Strongyloides stercoralis (Threadworm)

Taxonomy: cellular organisms; Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Protostomia; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Tylenchina; Panagrolaimomorpha; Strongyloidoidea; Strongyloididae; Strongyloides

Average proteome isoelectric point is 7.06

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 12851 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A0K0DVY7|A0A0K0DVY7_STRER Uncharacterized protein OS=Strongyloides stercoralis OX=6248 PE=4 SV=1
MM1 pKa = 7.25ITLQEE6 pKa = 3.78VSIPRR11 pKa = 11.84EE12 pKa = 4.21GVCFTEE18 pKa = 4.51EE19 pKa = 3.83NVQLFHH25 pKa = 6.9EE26 pKa = 4.61VEE28 pKa = 4.3KK29 pKa = 11.21VSNGTLYY36 pKa = 10.28IGEE39 pKa = 4.6RR40 pKa = 11.84NITWIEE46 pKa = 3.94DD47 pKa = 3.5GKK49 pKa = 11.22GLGIIIPYY57 pKa = 8.61QALVTHH63 pKa = 7.15GISNDD68 pKa = 2.59INAFPDD74 pKa = 2.99RR75 pKa = 11.84CLFLTIDD82 pKa = 3.39ASKK85 pKa = 11.52VNFNVSSSEE94 pKa = 3.65EE95 pKa = 4.18DD96 pKa = 2.98MDD98 pKa = 5.56NDD100 pKa = 5.03DD101 pKa = 4.83EE102 pKa = 4.75YY103 pKa = 11.49EE104 pKa = 4.41CIYY107 pKa = 10.63LRR109 pKa = 11.84LVPANDD115 pKa = 3.55SLNIMFQMMTEE126 pKa = 4.07CQEE129 pKa = 4.07MNPDD133 pKa = 3.79EE134 pKa = 4.88EE135 pKa = 5.51DD136 pKa = 3.43MEE138 pKa = 4.85EE139 pKa = 4.46DD140 pKa = 3.9FSSGLQVVNGGSSDD154 pKa = 3.21WYY156 pKa = 10.45GVTDD160 pKa = 4.2NEE162 pKa = 4.73PFPDD166 pKa = 3.68MSDD169 pKa = 2.94QGMANYY175 pKa = 10.02DD176 pKa = 3.39RR177 pKa = 11.84LFGNKK182 pKa = 9.56NNDD185 pKa = 3.32SMDD188 pKa = 3.82DD189 pKa = 3.32

Molecular weight: 21.4 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A0K0DUM0|A0A0K0DUM0_STRER Uncharacterized protein OS=Strongyloides stercoralis OX=6248 PE=4 SV=1
MM1 pKa = 7.44KK2 pKa = 10.54FIFSSVLVIILLSHH16 pKa = 7.38KK17 pKa = 10.23IFSQQLSVQPAQTKK31 pKa = 9.97IFAAPVFTSNNAIEE45 pKa = 4.33IDD47 pKa = 3.96GEE49 pKa = 4.24KK50 pKa = 10.37KK51 pKa = 10.32RR52 pKa = 11.84LFKK55 pKa = 10.7IGAARR60 pKa = 11.84DD61 pKa = 4.03GVQKK65 pKa = 10.97AILDD69 pKa = 4.01EE70 pKa = 4.34VQPSQTVDD78 pKa = 3.92DD79 pKa = 4.35ISDD82 pKa = 3.69FNEE85 pKa = 4.06DD86 pKa = 2.96NTIFGAYY93 pKa = 9.68DD94 pKa = 3.46EE95 pKa = 5.49EE96 pKa = 4.37IVEE99 pKa = 4.47PVKK102 pKa = 9.63EE103 pKa = 4.31TPIFIPKK110 pKa = 10.16LYY112 pKa = 10.29RR113 pKa = 11.84ADD115 pKa = 3.59KK116 pKa = 10.87DD117 pKa = 3.77EE118 pKa = 4.47PTTTTTTTTTTTTRR132 pKa = 11.84RR133 pKa = 11.84PTTTRR138 pKa = 11.84QTVTTRR144 pKa = 11.84ITTLAPHH151 pKa = 5.23TTVRR155 pKa = 11.84TIQNNRR161 pKa = 11.84IPQTNQINSIPQSFVPSRR179 pKa = 11.84MISPPRR185 pKa = 11.84QPQQISGLQTIPPQIVPRR203 pKa = 11.84PNVIQPLPQQQFQFRR218 pKa = 11.84QNIRR222 pKa = 11.84PQPVLQTRR230 pKa = 11.84TGFSTPPPRR239 pKa = 11.84VISTTLRR246 pKa = 11.84PIITRR251 pKa = 11.84QPQTFPTLAPVTSTSRR267 pKa = 11.84PLRR270 pKa = 11.84PFIPQQPNPRR280 pKa = 11.84NSQNLRR286 pKa = 11.84TGVCRR291 pKa = 11.84ASIFYY296 pKa = 8.26LTSVPSSQDD305 pKa = 2.9FQTQFTHH312 pKa = 6.09FAVVVSVDD320 pKa = 3.11QCARR324 pKa = 11.84TCHH327 pKa = 5.73EE328 pKa = 4.67FNCAVAIYY336 pKa = 9.85DD337 pKa = 4.33ASTKK341 pKa = 9.93HH342 pKa = 5.86CQFVPSTAFSIRR354 pKa = 11.84EE355 pKa = 4.18GQCPNWPNPLYY366 pKa = 10.61RR367 pKa = 11.84NNVLGLNNIRR377 pKa = 11.84ISCVTCQRR385 pKa = 11.84RR386 pKa = 11.84RR387 pKa = 11.84RR388 pKa = 11.84NFQRR392 pKa = 11.84VRR394 pKa = 11.84GMSRR398 pKa = 11.84GFGLTNRR405 pKa = 11.84RR406 pKa = 11.84QPTTIQTTRR415 pKa = 11.84FLPQTPNRR423 pKa = 11.84NIPTNPQNSNIRR435 pKa = 11.84LNGVILKK442 pKa = 10.09QPTSYY447 pKa = 10.79AISSNEE453 pKa = 3.7MEE455 pKa = 4.58KK456 pKa = 10.88LLSEE460 pKa = 4.2SSITKK465 pKa = 10.2GSQLSEE471 pKa = 3.9INAA474 pKa = 3.86

Molecular weight: 53.41 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

12823

28

12851

5840225

8

11712

454.5

52.06

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

3.884 ± 0.022

2.068 ± 0.019

5.441 ± 0.02

6.628 ± 0.03

4.914 ± 0.019

4.68 ± 0.025

1.948 ± 0.01

8.541 ± 0.022

8.703 ± 0.026

8.663 ± 0.026

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.166 ± 0.01

7.677 ± 0.033

3.827 ± 0.017

3.351 ± 0.015

3.819 ± 0.018

8.02 ± 0.029

5.602 ± 0.03

5.07 ± 0.017

0.894 ± 0.007

4.101 ± 0.016
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski