Human T-cell leukemia virus 3 (strain Pyl43) (HTLV-3)

Taxonomy: Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes; Ortervirales; Retroviridae; Orthoretrovirinae; Deltaretrovirus; Primate T-lymphotropic virus 3

Average proteome isoelectric point is 7.96

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 6 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>sp|Q4U0X7|TAX_HTL3P Protein Tax-3 OS=Human T-cell leukemia virus 3 (strain Pyl43) OX=406769 GN=tax PE=1 SV=2
MM1 pKa = 7.36AHH3 pKa = 6.69FPGFGQSLLYY13 pKa = 10.27GYY15 pKa = 9.11PVYY18 pKa = 11.22VFGDD22 pKa = 4.2CVQADD27 pKa = 3.85WCPISGGLCSARR39 pKa = 11.84LHH41 pKa = 5.8RR42 pKa = 11.84HH43 pKa = 5.65ALLATCPEE51 pKa = 4.36HH52 pKa = 7.0QITWDD57 pKa = 4.46PIDD60 pKa = 3.67GRR62 pKa = 11.84VVSSALQYY70 pKa = 9.91LIPRR74 pKa = 11.84LPSFPTQRR82 pKa = 11.84TTRR85 pKa = 11.84TLKK88 pKa = 10.79VLTPPTTATTPKK100 pKa = 9.33VPPSFFHH107 pKa = 6.74AVKK110 pKa = 10.39KK111 pKa = 8.26HH112 pKa = 4.14TPFRR116 pKa = 11.84NNCLEE121 pKa = 4.13LTLGEE126 pKa = 4.38QLPAMSFPDD135 pKa = 3.86PGLRR139 pKa = 11.84PQNVYY144 pKa = 9.05TIWGCSVVCLYY155 pKa = 10.69LYY157 pKa = 10.33QLSPPMTWPLIPHH170 pKa = 6.91VIFCHH175 pKa = 6.22PEE177 pKa = 3.45QLGAFLTRR185 pKa = 11.84VPTKK189 pKa = 10.37RR190 pKa = 11.84LEE192 pKa = 3.91EE193 pKa = 3.87LLYY196 pKa = 10.73KK197 pKa = 10.39IFLSTGAIIILPEE210 pKa = 3.89NCFPTTLFQPTRR222 pKa = 11.84APAIQAPWHH231 pKa = 6.26TGLLPCQKK239 pKa = 10.39EE240 pKa = 4.08IVTPGLIWTFTDD252 pKa = 4.92GSPMISGPCPKK263 pKa = 9.84EE264 pKa = 3.91GQPSLVVQSSTFIFQQFQTKK284 pKa = 9.91ASHH287 pKa = 6.24PAFLLSHH294 pKa = 7.07KK295 pKa = 9.91LIQYY299 pKa = 10.48SSFHH303 pKa = 6.19SLHH306 pKa = 6.64LLFEE310 pKa = 4.97EE311 pKa = 5.02YY312 pKa = 9.69STVPFSLLFNEE323 pKa = 4.62KK324 pKa = 9.75GANVSDD330 pKa = 3.96DD331 pKa = 3.89EE332 pKa = 4.62PRR334 pKa = 11.84GGPQPPTGGQIAEE347 pKa = 4.3SSVV350 pKa = 2.9

Molecular weight: 38.87 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>sp|Q09SZ9|PRO_HTL3P Gag-Pro polyprotein OS=Human T-cell leukemia virus 3 (strain Pyl43) OX=406769 GN=gag-pro PE=3 SV=3
MM1 pKa = 7.86PKK3 pKa = 8.98TRR5 pKa = 11.84KK6 pKa = 8.8QRR8 pKa = 11.84SRR10 pKa = 11.84RR11 pKa = 11.84PRR13 pKa = 11.84NQRR16 pKa = 11.84PSTPWPISQVSDD28 pKa = 3.26RR29 pKa = 11.84AFSTGTLSTFSATVYY44 pKa = 10.41RR45 pKa = 11.84PIGAPFLGGFVPLGYY60 pKa = 8.38TAMPCWPRR68 pKa = 11.84APNIRR73 pKa = 11.84LPGTPSMDD81 pKa = 3.3ALSAQLYY88 pKa = 7.05NTLSLGSPPSPPKK101 pKa = 10.05EE102 pKa = 3.85LPAPSRR108 pKa = 11.84FSPPQPLLRR117 pKa = 11.84PPRR120 pKa = 11.84FLHH123 pKa = 6.85PSSTPLKK130 pKa = 8.45NTPPSEE136 pKa = 4.57TIASSSPWEE145 pKa = 4.52SSCQPCPSPTLGSGPKK161 pKa = 9.52TSTPYY166 pKa = 10.5GAAPSCVSTSISSPPPP182 pKa = 3.48

Molecular weight: 19.39 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

6

0

6

3471

182

1440

578.5

64.07

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.886 ± 0.423

2.593 ± 0.251

3.688 ± 0.39

3.198 ± 0.318

3.083 ± 0.545

5.272 ± 0.182

3.515 ± 0.429

4.811 ± 0.443

4.264 ± 0.384

12.388 ± 0.783

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

0.835 ± 0.165

3.601 ± 0.383

11.639 ± 1.277

6.828 ± 0.548

4.667 ± 0.252

8.096 ± 1.012

5.82 ± 0.578

4.408 ± 0.287

1.901 ± 0.141

2.506 ± 0.279
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski