Molossus molossus circovirus 2

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cressdnaviricota; Arfiviricetes; Cirlivirales; Circoviridae; Circovirus; unclassified Circovirus

Average proteome isoelectric point is 8.11

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 2 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A2I2MP64|A0A2I2MP64_9CIRC Capsid OS=Molossus molossus circovirus 2 OX=1959843 GN=Cap PE=3 SV=1
MM1 pKa = 7.39AAAPKK6 pKa = 9.93LVRR9 pKa = 11.84KK10 pKa = 9.82SRR12 pKa = 11.84FSNQEE17 pKa = 3.47NEE19 pKa = 4.0FDD21 pKa = 3.43RR22 pKa = 11.84GEE24 pKa = 4.04IGGSSRR30 pKa = 11.84SVCFTLNNYY39 pKa = 7.66TEE41 pKa = 4.34NDD43 pKa = 3.28LEE45 pKa = 4.67IIKK48 pKa = 8.64KK49 pKa = 6.5TWPKK53 pKa = 8.55IASYY57 pKa = 10.38YY58 pKa = 10.0VVGLEE63 pKa = 4.17VGEE66 pKa = 4.58SGTPHH71 pKa = 5.73LQGYY75 pKa = 7.28VEE77 pKa = 4.31WNSSKK82 pKa = 10.63EE83 pKa = 3.63FSTMHH88 pKa = 6.85KK89 pKa = 9.75IFSHH93 pKa = 5.79RR94 pKa = 11.84AHH96 pKa = 7.08WKK98 pKa = 9.56RR99 pKa = 11.84RR100 pKa = 11.84YY101 pKa = 9.35QNSTAEE107 pKa = 4.02QAAKK111 pKa = 9.92YY112 pKa = 8.9CKK114 pKa = 9.96KK115 pKa = 10.64GEE117 pKa = 3.97QSKK120 pKa = 10.64EE121 pKa = 3.63EE122 pKa = 4.09WEE124 pKa = 4.44KK125 pKa = 11.11FGSSGPNFGKK135 pKa = 9.92NANFFEE141 pKa = 5.4HH142 pKa = 7.35GEE144 pKa = 3.85ISNQGEE150 pKa = 3.98RR151 pKa = 11.84NDD153 pKa = 3.43IKK155 pKa = 10.94EE156 pKa = 4.23AMSMIKK162 pKa = 10.42NGATEE167 pKa = 3.86IEE169 pKa = 4.48VFEE172 pKa = 4.31ACPRR176 pKa = 11.84VSMQYY181 pKa = 10.82LKK183 pKa = 11.32GMDD186 pKa = 3.82RR187 pKa = 11.84YY188 pKa = 10.72RR189 pKa = 11.84LLCQKK194 pKa = 8.13QARR197 pKa = 11.84KK198 pKa = 10.12GYY200 pKa = 8.14NKK202 pKa = 10.44KK203 pKa = 10.04NVRR206 pKa = 11.84VYY208 pKa = 9.89WGEE211 pKa = 3.81TGTGKK216 pKa = 8.15TRR218 pKa = 11.84SALEE222 pKa = 4.0EE223 pKa = 4.15FPDD226 pKa = 5.14AFICTAGITGLWWDD240 pKa = 4.49GYY242 pKa = 10.97DD243 pKa = 3.96GEE245 pKa = 4.49EE246 pKa = 3.93TVIIDD251 pKa = 3.47EE252 pKa = 4.64FRR254 pKa = 11.84GNNCPLSMLLTILDD268 pKa = 4.87GYY270 pKa = 10.75ASQVSIRR277 pKa = 11.84GGSKK281 pKa = 9.28ILYY284 pKa = 9.16AKK286 pKa = 9.51TIIITSNIHH295 pKa = 5.38PDD297 pKa = 2.86EE298 pKa = 4.58WYY300 pKa = 10.99VNSDD304 pKa = 4.2DD305 pKa = 3.99YY306 pKa = 12.06SKK308 pKa = 11.33AALKK312 pKa = 10.51RR313 pKa = 11.84RR314 pKa = 11.84IDD316 pKa = 3.43STLFFSNKK324 pKa = 7.49EE325 pKa = 4.02NRR327 pKa = 11.84KK328 pKa = 8.29KK329 pKa = 8.83TAEE332 pKa = 3.98VEE334 pKa = 4.15GNTRR338 pKa = 11.84SSTSLEE344 pKa = 4.01KK345 pKa = 10.37FLKK348 pKa = 10.9LNLL351 pKa = 3.76

Molecular weight: 40.03 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A2I2MP64|A0A2I2MP64_9CIRC Capsid OS=Molossus molossus circovirus 2 OX=1959843 GN=Cap PE=3 SV=1
MM1 pKa = 7.42PAKK4 pKa = 10.37KK5 pKa = 9.68IYY7 pKa = 10.78NPAAYY12 pKa = 9.27HH13 pKa = 5.45AAVRR17 pKa = 11.84RR18 pKa = 11.84NAAAAKK24 pKa = 9.25SAAVAHH30 pKa = 5.97ARR32 pKa = 11.84KK33 pKa = 8.84HH34 pKa = 4.63ATHH37 pKa = 7.41FIQRR41 pKa = 11.84GVKK44 pKa = 9.66SADD47 pKa = 3.57RR48 pKa = 11.84AVKK51 pKa = 10.18KK52 pKa = 10.26YY53 pKa = 10.14VSSGAMSRR61 pKa = 11.84DD62 pKa = 3.4LQRR65 pKa = 11.84GARR68 pKa = 11.84AVTRR72 pKa = 11.84SAIMSGSGDD81 pKa = 3.56INIHH85 pKa = 5.44KK86 pKa = 10.58SKK88 pKa = 10.39LRR90 pKa = 11.84EE91 pKa = 3.68RR92 pKa = 11.84AYY94 pKa = 9.89DD95 pKa = 3.61TSGHH99 pKa = 5.13PTVRR103 pKa = 11.84LTEE106 pKa = 4.19TGEE109 pKa = 3.55MTIIHH114 pKa = 6.68RR115 pKa = 11.84EE116 pKa = 4.04YY117 pKa = 10.18IGEE120 pKa = 4.66LISGTQNPANFTSQNYY136 pKa = 9.56GINPGNPGCFPWLSTVSNSFQNYY159 pKa = 8.6KK160 pKa = 9.99FHH162 pKa = 7.11SLVFEE167 pKa = 4.14YY168 pKa = 11.18VPLTSEE174 pKa = 4.04STATSTGALVGMGSVMMATQYY195 pKa = 11.3DD196 pKa = 4.36SSLGPYY202 pKa = 9.61LNKK205 pKa = 10.08PQMEE209 pKa = 4.19NSDD212 pKa = 3.95FATSAKK218 pKa = 9.62PSSAMVHH225 pKa = 5.16VVEE228 pKa = 5.38CNSKK232 pKa = 9.59YY233 pKa = 10.69NVLGEE238 pKa = 4.5YY239 pKa = 9.99YY240 pKa = 10.4VSSDD244 pKa = 3.22TTVSNTNISNADD256 pKa = 2.7IRR258 pKa = 11.84MQNVGIFQIASVGIPTYY275 pKa = 10.87GSVAIDD281 pKa = 3.91LGEE284 pKa = 3.79IWVSYY289 pKa = 10.7SITLYY294 pKa = 10.83KK295 pKa = 8.59PTIYY299 pKa = 10.48GALAAIQSSHH309 pKa = 4.6YY310 pKa = 9.63TNGAVSGAPTSANPFGTVTTSNQPTPATNNQLPLTFTSGSTFAFPLAITEE360 pKa = 4.1GNYY363 pKa = 10.54LIVYY367 pKa = 8.78QCVSGNAVTFSFTGIVTTNCTALTCWSTPMTT398 pKa = 4.35

Molecular weight: 42.6 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

2

0

2

749

351

398

374.5

41.32

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

8.411 ± 1.647

1.469 ± 0.163

2.937 ± 0.52

5.874 ± 2.199

4.005 ± 0.375

7.61 ± 0.249

2.136 ± 0.289

5.874 ± 0.074

6.008 ± 1.915

5.34 ± 0.436

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.403 ± 0.277

6.542 ± 0.007

3.738 ± 0.989

3.071 ± 0.15

4.539 ± 0.786

10.147 ± 0.892

8.144 ± 1.659

5.607 ± 1.098

1.469 ± 0.55

4.673 ± 0.271
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski