Amino acid dipepetide frequency for Arabidopsis lyrata subsp. lyrata (Lyre-leaved rock-cress)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.687AlaAla: 5.687 ± 0.031	1.149AlaCys: 1.149 ± 0.011	2.861AlaAsp: 2.861 ± 0.014	4.019AlaGlu: 4.019 ± 0.023	2.657AlaPhe: 2.657 ± 0.017	3.783AlaGly: 3.783 ± 0.021	1.156AlaHis: 1.156 ± 0.011	3.566AlaIle: 3.566 ± 0.02	3.905AlaLys: 3.905 ± 0.021	6.086AlaLeu: 6.086 ± 0.031	1.763AlaMet: 1.763 ± 0.012	2.424AlaAsn: 2.424 ± 0.015	2.528AlaPro: 2.528 ± 0.017	1.856AlaGln: 1.856 ± 0.014	3.197AlaArg: 3.197 ± 0.016	5.663AlaSer: 5.663 ± 0.026	3.569AlaThr: 3.569 ± 0.021	4.633AlaVal: 4.633 ± 0.022	0.697AlaTrp: 0.697 ± 0.008	1.744AlaTyr: 1.744 ± 0.013	0.0AlaXaa: 0.0 ± 0.0
Cys	0.892CysAla: 0.892 ± 0.008	0.552CysCys: 0.552 ± 0.009	0.944CysAsp: 0.944 ± 0.01	0.91CysGlu: 0.91 ± 0.009	1.004CysPhe: 1.004 ± 0.009	1.401CysGly: 1.401 ± 0.014	0.444CysHis: 0.444 ± 0.006	1.017CysIle: 1.017 ± 0.01	1.134CysLys: 1.134 ± 0.011	1.946CysLeu: 1.946 ± 0.016	0.413CysMet: 0.413 ± 0.006	0.829CysAsn: 0.829 ± 0.01	0.868CysPro: 0.868 ± 0.01	0.53CysGln: 0.53 ± 0.007	1.087CysArg: 1.087 ± 0.01	1.821CysSer: 1.821 ± 0.014	0.834CysThr: 0.834 ± 0.01	1.223CysVal: 1.223 ± 0.01	0.244CysTrp: 0.244 ± 0.005	0.585CysTyr: 0.585 ± 0.007	0.0CysXaa: 0.0 ± 0.0
Asp	3.157AspAla: 3.157 ± 0.018	0.966AspCys: 0.966 ± 0.009	3.857AspAsp: 3.857 ± 0.03	4.23AspGlu: 4.23 ± 0.026	2.434AspPhe: 2.434 ± 0.015	3.729AspGly: 3.729 ± 0.018	1.263AspHis: 1.263 ± 0.012	2.983AspIle: 2.983 ± 0.017	2.833AspLys: 2.833 ± 0.017	5.258AspLeu: 5.258 ± 0.022	1.348AspMet: 1.348 ± 0.011	2.063AspAsn: 2.063 ± 0.012	2.629AspPro: 2.629 ± 0.016	1.792AspGln: 1.792 ± 0.013	2.385AspArg: 2.385 ± 0.016	4.415AspSer: 4.415 ± 0.023	2.293AspThr: 2.293 ± 0.012	3.744AspVal: 3.744 ± 0.019	0.703AspTrp: 0.703 ± 0.008	1.615AspTyr: 1.615 ± 0.012	0.0AspXaa: 0.0 ± 0.0
Glu	4.738GluAla: 4.738 ± 0.028	0.874GluCys: 0.874 ± 0.01	4.2GluAsp: 4.2 ± 0.024	6.962GluGlu: 6.962 ± 0.042	2.494GluPhe: 2.494 ± 0.015	3.449GluGly: 3.449 ± 0.017	1.193GluHis: 1.193 ± 0.009	4.065GluIle: 4.065 ± 0.021	5.184GluLys: 5.184 ± 0.03	5.747GluLeu: 5.747 ± 0.028	1.864GluMet: 1.864 ± 0.015	3.175GluAsn: 3.175 ± 0.018	2.19GluPro: 2.19 ± 0.013	2.032GluGln: 2.032 ± 0.016	3.474GluArg: 3.474 ± 0.024	4.944GluSer: 4.944 ± 0.025	3.661GluThr: 3.661 ± 0.022	4.074GluVal: 4.074 ± 0.024	0.755GluTrp: 0.755 ± 0.008	1.671GluTyr: 1.671 ± 0.012	0.0GluXaa: 0.0 ± 0.0
Phe	2.498PheAla: 2.498 ± 0.015	0.943PheCys: 0.943 ± 0.01	2.498PheAsp: 2.498 ± 0.015	2.382PheGlu: 2.382 ± 0.016	2.16PhePhe: 2.16 ± 0.016	3.083PheGly: 3.083 ± 0.018	1.109PheHis: 1.109 ± 0.01	2.125PheIle: 2.125 ± 0.015	2.311PheLys: 2.311 ± 0.014	4.457PheLeu: 4.457 ± 0.022	1.052PheMet: 1.052 ± 0.01	1.782PheAsn: 1.782 ± 0.012	2.106PhePro: 2.106 ± 0.016	1.466PheGln: 1.466 ± 0.01	2.183PheArg: 2.183 ± 0.016	4.236PheSer: 4.236 ± 0.02	2.19PheThr: 2.19 ± 0.015	3.016PheVal: 3.016 ± 0.016	0.573PheTrp: 0.573 ± 0.007	1.315PheTyr: 1.315 ± 0.011	0.0PheXaa: 0.0 ± 0.0
Gly	3.446GlyAla: 3.446 ± 0.022	1.259GlyCys: 1.259 ± 0.013	3.49GlyAsp: 3.49 ± 0.019	3.828GlyGlu: 3.828 ± 0.021	3.315GlyPhe: 3.315 ± 0.018	5.503GlyGly: 5.503 ± 0.051	1.423GlyHis: 1.423 ± 0.012	3.51GlyIle: 3.51 ± 0.018	4.204GlyLys: 4.204 ± 0.021	5.746GlyLeu: 5.746 ± 0.023	1.441GlyMet: 1.441 ± 0.013	3.037GlyAsn: 3.037 ± 0.018	2.218GlyPro: 2.218 ± 0.018	1.912GlyGln: 1.912 ± 0.016	3.469GlyArg: 3.469 ± 0.023	5.801GlySer: 5.801 ± 0.025	3.134GlyThr: 3.134 ± 0.02	4.113GlyVal: 4.113 ± 0.022	0.848GlyTrp: 0.848 ± 0.01	2.132GlyTyr: 2.132 ± 0.016	0.0GlyXaa: 0.0 ± 0.0
His	1.163HisAla: 1.163 ± 0.011	0.522HisCys: 0.522 ± 0.006	1.111HisAsp: 1.111 ± 0.01	1.275HisGlu: 1.275 ± 0.011	0.991HisPhe: 0.991 ± 0.008	1.653HisGly: 1.653 ± 0.013	0.955HisHis: 0.955 ± 0.014	1.172HisIle: 1.172 ± 0.011	1.206HisLys: 1.206 ± 0.011	2.249HisLeu: 2.249 ± 0.015	0.566HisMet: 0.566 ± 0.006	0.95HisAsn: 0.95 ± 0.008	1.204HisPro: 1.204 ± 0.012	1.001HisGln: 1.001 ± 0.01	1.387HisArg: 1.387 ± 0.012	1.76HisSer: 1.76 ± 0.012	0.929HisThr: 0.929 ± 0.009	1.515HisVal: 1.515 ± 0.012	0.288HisTrp: 0.288 ± 0.005	0.712HisTyr: 0.712 ± 0.008	0.0HisXaa: 0.0 ± 0.0
Ile	3.451IleAla: 3.451 ± 0.022	1.169IleCys: 1.169 ± 0.01	3.05IleAsp: 3.05 ± 0.018	3.281IleGlu: 3.281 ± 0.02	2.343IlePhe: 2.343 ± 0.015	3.477IleGly: 3.477 ± 0.022	1.297IleHis: 1.297 ± 0.011	2.801IleIle: 2.801 ± 0.019	3.057IleLys: 3.057 ± 0.018	5.178IleLeu: 5.178 ± 0.023	1.158IleMet: 1.158 ± 0.01	2.239IleAsn: 2.239 ± 0.016	2.881IlePro: 2.881 ± 0.019	1.908IleGln: 1.908 ± 0.013	2.768IleArg: 2.768 ± 0.015	5.0IleSer: 5.0 ± 0.021	2.794IleThr: 2.794 ± 0.016	3.628IleVal: 3.628 ± 0.019	0.727IleTrp: 0.727 ± 0.008	1.611IleTyr: 1.611 ± 0.013	0.0IleXaa: 0.0 ± 0.0
Lys	3.973LysAla: 3.973 ± 0.022	0.991LysCys: 0.991 ± 0.01	3.311LysAsp: 3.311 ± 0.021	4.898LysGlu: 4.898 ± 0.032	2.224LysPhe: 2.224 ± 0.017	3.498LysGly: 3.498 ± 0.018	1.329LysHis: 1.329 ± 0.01	3.57LysIle: 3.57 ± 0.018	5.451LysLys: 5.451 ± 0.04	6.143LysLeu: 6.143 ± 0.028	1.581LysMet: 1.581 ± 0.012	2.836LysAsn: 2.836 ± 0.017	2.992LysPro: 2.992 ± 0.017	2.29LysGln: 2.29 ± 0.017	3.877LysArg: 3.877 ± 0.021	4.936LysSer: 4.936 ± 0.026	3.41LysThr: 3.41 ± 0.019	3.829LysVal: 3.829 ± 0.02	0.824LysTrp: 0.824 ± 0.009	1.601LysTyr: 1.601 ± 0.013	0.0LysXaa: 0.0 ± 0.0
Leu	6.154LeuAla: 6.154 ± 0.028	1.937LeuCys: 1.937 ± 0.015	4.989LeuAsp: 4.989 ± 0.024	6.206LeuGlu: 6.206 ± 0.037	3.986LeuPhe: 3.986 ± 0.021	5.622LeuGly: 5.622 ± 0.025	2.369LeuHis: 2.369 ± 0.016	4.786LeuIle: 4.786 ± 0.026	6.207LeuLys: 6.207 ± 0.03	9.682LeuLeu: 9.682 ± 0.047	2.287LeuMet: 2.287 ± 0.015	3.849LeuAsn: 3.849 ± 0.019	4.951LeuPro: 4.951 ± 0.025	3.825LeuGln: 3.825 ± 0.025	5.48LeuArg: 5.48 ± 0.025	8.512LeuSer: 8.512 ± 0.036	4.58LeuThr: 4.58 ± 0.023	6.535LeuVal: 6.535 ± 0.03	1.18LeuTrp: 1.18 ± 0.011	2.523LeuTyr: 2.523 ± 0.017	0.0LeuXaa: 0.0 ± 0.0
Met	2.082MetAla: 2.082 ± 0.013	0.35MetCys: 0.35 ± 0.005	1.395MetAsp: 1.395 ± 0.012	2.044MetGlu: 2.044 ± 0.014	0.939MetPhe: 0.939 ± 0.011	1.537MetGly: 1.537 ± 0.013	0.463MetHis: 0.463 ± 0.006	1.372MetIle: 1.372 ± 0.011	1.748MetLys: 1.748 ± 0.014	2.084MetLeu: 2.084 ± 0.015	0.784MetMet: 0.784 ± 0.01	1.086MetAsn: 1.086 ± 0.009	0.945MetPro: 0.945 ± 0.009	0.816MetGln: 0.816 ± 0.009	1.293MetArg: 1.293 ± 0.011	1.942MetSer: 1.942 ± 0.012	1.144MetThr: 1.144 ± 0.009	1.768MetVal: 1.768 ± 0.013	0.272MetTrp: 0.272 ± 0.005	0.627MetTyr: 0.627 ± 0.007	0.0MetXaa: 0.0 ± 0.0
Asn	2.499AsnAla: 2.499 ± 0.015	0.81AsnCys: 0.81 ± 0.01	2.081AsnAsp: 2.081 ± 0.012	2.458AsnGlu: 2.458 ± 0.014	1.816AsnPhe: 1.816 ± 0.015	3.227AsnGly: 3.227 ± 0.02	1.157AsnHis: 1.157 ± 0.01	2.431AsnIle: 2.431 ± 0.014	2.491AsnLys: 2.491 ± 0.018	4.573AsnLeu: 4.573 ± 0.026	1.097AsnMet: 1.097 ± 0.008	2.376AsnAsn: 2.376 ± 0.024	2.477AsnPro: 2.477 ± 0.016	1.722AsnGln: 1.722 ± 0.013	2.205AsnArg: 2.205 ± 0.014	3.691AsnSer: 3.691 ± 0.019	2.052AsnThr: 2.052 ± 0.014	2.882AsnVal: 2.882 ± 0.015	0.556AsnTrp: 0.556 ± 0.008	1.293AsnTyr: 1.293 ± 0.01	0.0AsnXaa: 0.0 ± 0.0
Pro	2.725ProAla: 2.725 ± 0.019	0.763ProCys: 0.763 ± 0.009	2.418ProAsp: 2.418 ± 0.015	3.302ProGlu: 3.302 ± 0.02	1.954ProPhe: 1.954 ± 0.014	2.592ProGly: 2.592 ± 0.018	1.018ProHis: 1.018 ± 0.009	2.289ProIle: 2.289 ± 0.017	2.853ProLys: 2.853 ± 0.019	4.171ProLeu: 4.171 ± 0.02	1.026ProMet: 1.026 ± 0.01	2.223ProAsn: 2.223 ± 0.015	3.895ProPro: 3.895 ± 0.05	1.699ProGln: 1.699 ± 0.015	2.461ProArg: 2.461 ± 0.02	4.935ProSer: 4.935 ± 0.027	2.548ProThr: 2.548 ± 0.019	3.159ProVal: 3.159 ± 0.017	0.602ProTrp: 0.602 ± 0.008	1.332ProTyr: 1.332 ± 0.014	0.0ProXaa: 0.0 ± 0.0
Gln	2.14GlnAla: 2.14 ± 0.015	0.558GlnCys: 0.558 ± 0.008	1.606GlnAsp: 1.606 ± 0.012	2.386GlnGlu: 2.386 ± 0.016	1.321GlnPhe: 1.321 ± 0.011	1.961GlnGly: 1.961 ± 0.015	0.808GlnHis: 0.808 ± 0.01	1.973GlnIle: 1.973 ± 0.013	2.185GlnLys: 2.185 ± 0.018	3.165GlnLeu: 3.165 ± 0.021	0.911GlnMet: 0.911 ± 0.01	1.673GlnAsn: 1.673 ± 0.012	1.657GlnPro: 1.657 ± 0.016	1.878GlnGln: 1.878 ± 0.027	2.145GlnArg: 2.145 ± 0.016	2.761GlnSer: 2.761 ± 0.019	1.791GlnThr: 1.791 ± 0.015	2.21GlnVal: 2.21 ± 0.013	0.449GlnTrp: 0.449 ± 0.006	0.872GlnTyr: 0.872 ± 0.01	0.0GlnXaa: 0.0 ± 0.0
Arg	3.022ArgAla: 3.022 ± 0.016	1.049ArgCys: 1.049 ± 0.01	2.811ArgAsp: 2.811 ± 0.02	3.517ArgGlu: 3.517 ± 0.021	2.593ArgPhe: 2.593 ± 0.015	3.222ArgGly: 3.222 ± 0.02	1.213ArgHis: 1.213 ± 0.01	2.978ArgIle: 2.978 ± 0.018	3.873ArgLys: 3.873 ± 0.023	5.157ArgLeu: 5.157 ± 0.022	1.299ArgMet: 1.299 ± 0.012	2.551ArgAsn: 2.551 ± 0.014	2.284ArgPro: 2.284 ± 0.016	1.772ArgGln: 1.772 ± 0.012	4.2ArgArg: 4.2 ± 0.028	4.622ArgSer: 4.622 ± 0.026	2.495ArgThr: 2.495 ± 0.014	3.518ArgVal: 3.518 ± 0.018	0.765ArgTrp: 0.765 ± 0.009	1.515ArgTyr: 1.515 ± 0.012	0.0ArgXaa: 0.0 ± 0.0
Ser	4.945SerAla: 4.945 ± 0.025	1.723SerCys: 1.723 ± 0.012	4.645SerAsp: 4.645 ± 0.022	4.967SerGlu: 4.967 ± 0.027	4.192SerPhe: 4.192 ± 0.02	5.958SerGly: 5.958 ± 0.029	2.009SerHis: 2.009 ± 0.014	4.469SerIle: 4.469 ± 0.023	5.062SerLys: 5.062 ± 0.026	8.928SerLeu: 8.928 ± 0.03	2.071SerMet: 2.071 ± 0.012	3.904SerAsn: 3.904 ± 0.021	4.714SerPro: 4.714 ± 0.033	2.973SerGln: 2.973 ± 0.02	4.679SerArg: 4.679 ± 0.021	11.684SerSer: 11.684 ± 0.053	4.536SerThr: 4.536 ± 0.024	5.595SerVal: 5.595 ± 0.024	1.17SerTrp: 1.17 ± 0.01	2.42SerTyr: 2.42 ± 0.015	0.0SerXaa: 0.0 ± 0.0
Thr	3.297ThrAla: 3.297 ± 0.019	1.006ThrCys: 1.006 ± 0.01	2.362ThrAsp: 2.362 ± 0.014	3.122ThrGlu: 3.122 ± 0.016	2.109ThrPhe: 2.109 ± 0.013	3.411ThrGly: 3.411 ± 0.02	1.02ThrHis: 1.02 ± 0.009	2.808ThrIle: 2.808 ± 0.016	3.07ThrLys: 3.07 ± 0.018	4.766ThrLeu: 4.766 ± 0.022	1.235ThrMet: 1.235 ± 0.01	2.206ThrAsn: 2.206 ± 0.015	2.551ThrPro: 2.551 ± 0.021	1.581ThrGln: 1.581 ± 0.013	2.609ThrArg: 2.609 ± 0.018	4.687ThrSer: 4.687 ± 0.024	3.286ThrThr: 3.286 ± 0.021	3.626ThrVal: 3.626 ± 0.021	0.669ThrTrp: 0.669 ± 0.009	1.404ThrTyr: 1.404 ± 0.012	0.0ThrXaa: 0.0 ± 0.0
Val	4.668ValAla: 4.668 ± 0.026	1.207ValCys: 1.207 ± 0.011	3.777ValAsp: 3.777 ± 0.02	4.542ValGlu: 4.542 ± 0.021	3.005ValPhe: 3.005 ± 0.019	3.898ValGly: 3.898 ± 0.021	1.433ValHis: 1.433 ± 0.011	3.588ValIle: 3.588 ± 0.021	4.202ValLys: 4.202 ± 0.02	6.361ValLeu: 6.361 ± 0.025	1.685ValMet: 1.685 ± 0.013	2.669ValAsn: 2.669 ± 0.016	3.137ValPro: 3.137 ± 0.02	2.063ValGln: 2.063 ± 0.014	3.174ValArg: 3.174 ± 0.017	5.906ValSer: 5.906 ± 0.025	3.574ValThr: 3.574 ± 0.02	5.189ValVal: 5.189 ± 0.025	0.801ValTrp: 0.801 ± 0.009	2.033ValTyr: 2.033 ± 0.015	0.0ValXaa: 0.0 ± 0.0
Trp	0.686TrpAla: 0.686 ± 0.007	0.249TrpCys: 0.249 ± 0.005	0.704TrpAsp: 0.704 ± 0.009	0.764TrpGlu: 0.764 ± 0.008	0.603TrpPhe: 0.603 ± 0.008	0.714TrpGly: 0.714 ± 0.01	0.26TrpHis: 0.26 ± 0.005	0.774TrpIle: 0.774 ± 0.008	0.932TrpLys: 0.932 ± 0.008	1.207TrpLeu: 1.207 ± 0.011	0.342TrpMet: 0.342 ± 0.005	0.7TrpAsn: 0.7 ± 0.008	0.47TrpPro: 0.47 ± 0.007	0.39TrpGln: 0.39 ± 0.006	0.897TrpArg: 0.897 ± 0.009	1.028TrpSer: 1.028 ± 0.01	0.643TrpThr: 0.643 ± 0.008	0.79TrpVal: 0.79 ± 0.009	0.237TrpTrp: 0.237 ± 0.005	0.364TrpTyr: 0.364 ± 0.005	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.721TyrAla: 1.721 ± 0.013	0.602TyrCys: 0.602 ± 0.008	1.586TyrAsp: 1.586 ± 0.011	1.651TyrGlu: 1.651 ± 0.012	1.346TyrPhe: 1.346 ± 0.011	2.113TyrGly: 2.113 ± 0.016	0.69TyrHis: 0.69 ± 0.009	1.54TyrIle: 1.54 ± 0.012	1.659TyrLys: 1.659 ± 0.013	2.756TyrLeu: 2.756 ± 0.017	0.766TyrMet: 0.766 ± 0.007	1.322TyrAsn: 1.322 ± 0.012	1.267TyrPro: 1.267 ± 0.011	0.947TyrGln: 0.947 ± 0.008	1.488TyrArg: 1.488 ± 0.013	2.296TyrSer: 2.296 ± 0.015	1.363TyrThr: 1.363 ± 0.013	1.861TyrVal: 1.861 ± 0.015	0.395TyrTrp: 0.395 ± 0.007	1.008TyrTyr: 1.008 ± 0.01	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 32113 proteins (11683288 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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