Plasmodium falciparum (isolate Camp / Malaysia)

Taxonomy: cellular organisms; Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania); Plasmodium falciparum

Average proteome isoelectric point is 7.27

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 6105 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A024XCQ2|A0A024XCQ2_PLAFC Serine/threonine protein kinase OS=Plasmodium falciparum (isolate Camp / Malaysia) OX=5835 GN=PFMC_00900 PE=4 SV=1
MM1 pKa = 8.05DD2 pKa = 4.08KK3 pKa = 10.92FFFFFFFFFFCFYY16 pKa = 11.0FEE18 pKa = 5.78ISFCEE23 pKa = 3.8NDD25 pKa = 3.36KK26 pKa = 11.34KK27 pKa = 11.41EE28 pKa = 4.27EE29 pKa = 4.0LFSDD33 pKa = 4.14NEE35 pKa = 4.16LEE37 pKa = 4.62NIGGSAGDD45 pKa = 4.32IISSSSRR52 pKa = 11.84APSSKK57 pKa = 10.58GSDD60 pKa = 3.09NVPPNVDD67 pKa = 2.79IAGDD71 pKa = 3.58LLKK74 pKa = 10.93VMKK77 pKa = 10.0HH78 pKa = 5.42IPPPVVEE85 pKa = 4.23LNEE88 pKa = 4.11NEE90 pKa = 4.57FIDD93 pKa = 4.26PEE95 pKa = 4.52IVCEE99 pKa = 3.92RR100 pKa = 11.84DD101 pKa = 3.11YY102 pKa = 11.78DD103 pKa = 4.08KK104 pKa = 11.21PCPNDD109 pKa = 3.2YY110 pKa = 11.08NYY112 pKa = 10.8LGSVHH117 pKa = 6.81TDD119 pKa = 3.13DD120 pKa = 6.79DD121 pKa = 5.04EE122 pKa = 5.78ICAPSSTYY130 pKa = 10.57EE131 pKa = 3.93GG132 pKa = 3.44

Molecular weight: 15.0 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A024X6X8|A0A024X6X8_PLAFC Uncharacterized protein OS=Plasmodium falciparum (isolate Camp / Malaysia) OX=5835 GN=PFMC_02722 PE=4 SV=1
MM1 pKa = 7.28AHH3 pKa = 6.31GASRR7 pKa = 11.84YY8 pKa = 8.75KK9 pKa = 10.48KK10 pKa = 10.3SRR12 pKa = 11.84AKK14 pKa = 9.88MRR16 pKa = 11.84WKK18 pKa = 9.16WKK20 pKa = 9.29KK21 pKa = 9.72KK22 pKa = 6.67RR23 pKa = 11.84TRR25 pKa = 11.84RR26 pKa = 11.84LQKK29 pKa = 9.69KK30 pKa = 7.67RR31 pKa = 11.84RR32 pKa = 11.84KK33 pKa = 8.24MRR35 pKa = 11.84QRR37 pKa = 11.84SRR39 pKa = 3.22

Molecular weight: 5.09 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

6045

60

6105

3936546

16

10294

644.8

76.18

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

1.912 ± 0.024

1.784 ± 0.015

6.308 ± 0.027

6.949 ± 0.034

4.474 ± 0.025

2.759 ± 0.024

2.423 ± 0.013

9.389 ± 0.038

11.816 ± 0.04

7.681 ± 0.031

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.221 ± 0.012

14.478 ± 0.09

1.927 ± 0.018

2.744 ± 0.017

2.655 ± 0.016

6.383 ± 0.025

4.059 ± 0.018

3.729 ± 0.018

0.499 ± 0.008

5.81 ± 0.028
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski