Human immunodeficiency virus type 1 group O (isolate MVP5180) (HIV-1)

Taxonomy: Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes; Ortervirales; Retroviridae; Orthoretrovirinae; Lentivirus; Human immunodeficiency virus 1; HIV-1 group O

Average proteome isoelectric point is 7.56

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 10 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>sp|Q79670|ENV_HV1MV Envelope glycoprotein gp160 OS=Human immunodeficiency virus type 1 group O (isolate MVP5180) OX=388816 GN=env PE=3 SV=1
MM1 pKa = 7.01HH2 pKa = 7.05QEE4 pKa = 3.76NLLALIALSALCLINVLIWLFNLRR28 pKa = 11.84IYY30 pKa = 10.67LVQRR34 pKa = 11.84KK35 pKa = 7.14QDD37 pKa = 3.27RR38 pKa = 11.84RR39 pKa = 11.84EE40 pKa = 3.78QEE42 pKa = 3.29ILEE45 pKa = 3.91RR46 pKa = 11.84LRR48 pKa = 11.84RR49 pKa = 11.84IKK51 pKa = 10.15EE52 pKa = 3.61IRR54 pKa = 11.84DD55 pKa = 3.46DD56 pKa = 4.26SDD58 pKa = 3.99YY59 pKa = 11.46EE60 pKa = 4.55SNEE63 pKa = 3.91EE64 pKa = 3.87EE65 pKa = 4.06QQEE68 pKa = 4.42VMEE71 pKa = 5.72LIHH74 pKa = 6.37SHH76 pKa = 5.98GFANPMFEE84 pKa = 4.32LL85 pKa = 4.53

Molecular weight: 10.31 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>sp|Q79665|GAG_HV1MV Gag polyprotein OS=Human immunodeficiency virus type 1 group O (isolate MVP5180) OX=388816 GN=gag PE=3 SV=3
MM1 pKa = 7.81AGRR4 pKa = 11.84SEE6 pKa = 4.6EE7 pKa = 4.15DD8 pKa = 3.23QQLLQAIQIIKK19 pKa = 9.97ILYY22 pKa = 8.88QSNPCPTPAGSRR34 pKa = 11.84NARR37 pKa = 11.84KK38 pKa = 9.36NRR40 pKa = 11.84RR41 pKa = 11.84RR42 pKa = 11.84RR43 pKa = 11.84WRR45 pKa = 11.84RR46 pKa = 11.84RR47 pKa = 11.84QAQVDD52 pKa = 3.93SLATRR57 pKa = 11.84ILATVVHH64 pKa = 6.82GSQDD68 pKa = 3.35NNLVDD73 pKa = 5.45LPPLEE78 pKa = 4.14QLNIRR83 pKa = 11.84DD84 pKa = 4.12PEE86 pKa = 4.16ADD88 pKa = 3.74RR89 pKa = 11.84LPGTGTVDD97 pKa = 4.33PGTKK101 pKa = 10.36DD102 pKa = 2.99NN103 pKa = 4.37

Molecular weight: 11.58 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

9

1

10

3694

71

1446

369.4

41.81

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.768 ± 0.536

2.22 ± 0.496

3.952 ± 0.301

6.714 ± 0.756

2.382 ± 0.302

6.957 ± 0.408

2.491 ± 0.429

6.497 ± 0.844

6.687 ± 0.607

8.202 ± 0.589

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.301 ± 0.231

4.819 ± 0.647

5.847 ± 0.727

6.28 ± 0.319

5.604 ± 0.68

5.198 ± 0.362

5.766 ± 0.695

5.766 ± 0.596

2.653 ± 0.24

2.897 ± 0.257
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski