Amino acid dipepetide frequency for Platysternon megacephalum (big-headed turtle)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.051AlaAla: 7.051 ± 0.044	1.421AlaCys: 1.421 ± 0.015	2.969AlaAsp: 2.969 ± 0.02	4.899AlaGlu: 4.899 ± 0.03	2.495AlaPhe: 2.495 ± 0.02	5.074AlaGly: 5.074 ± 0.036	1.46AlaHis: 1.46 ± 0.012	2.892AlaIle: 2.892 ± 0.019	3.596AlaLys: 3.596 ± 0.022	6.988AlaLeu: 6.988 ± 0.035	1.586AlaMet: 1.586 ± 0.016	2.166AlaAsn: 2.166 ± 0.015	3.974AlaPro: 3.974 ± 0.032	3.055AlaGln: 3.055 ± 0.019	3.575AlaArg: 3.575 ± 0.028	5.586AlaSer: 5.586 ± 0.029	3.525AlaThr: 3.525 ± 0.024	4.81AlaVal: 4.81 ± 0.026	0.822AlaTrp: 0.822 ± 0.011	1.529AlaTyr: 1.529 ± 0.014	0.0AlaXaa: 0.0 ± 0.0
Cys	1.279CysAla: 1.279 ± 0.015	0.721CysCys: 0.721 ± 0.012	1.006CysAsp: 1.006 ± 0.016	1.266CysGlu: 1.266 ± 0.016	0.883CysPhe: 0.883 ± 0.012	1.493CysGly: 1.493 ± 0.018	0.662CysHis: 0.662 ± 0.008	1.063CysIle: 1.063 ± 0.012	1.26CysLys: 1.26 ± 0.016	2.229CysLeu: 2.229 ± 0.022	0.483CysMet: 0.483 ± 0.007	0.871CysAsn: 0.871 ± 0.013	1.44CysPro: 1.44 ± 0.021	1.11CysGln: 1.11 ± 0.015	1.3CysArg: 1.3 ± 0.014	2.14CysSer: 2.14 ± 0.021	1.248CysThr: 1.248 ± 0.016	1.308CysVal: 1.308 ± 0.017	0.328CysTrp: 0.328 ± 0.006	0.646CysTyr: 0.646 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	2.814AspAla: 2.814 ± 0.021	1.058AspCys: 1.058 ± 0.014	2.573AspAsp: 2.573 ± 0.021	3.402AspGlu: 3.402 ± 0.024	2.068AspPhe: 2.068 ± 0.016	3.248AspGly: 3.248 ± 0.026	1.09AspHis: 1.09 ± 0.01	2.621AspIle: 2.621 ± 0.022	2.586AspLys: 2.586 ± 0.017	4.783AspLeu: 4.783 ± 0.028	1.147AspMet: 1.147 ± 0.011	1.77AspAsn: 1.77 ± 0.014	2.73AspPro: 2.73 ± 0.019	1.836AspGln: 1.836 ± 0.016	2.334AspArg: 2.334 ± 0.019	4.117AspSer: 4.117 ± 0.028	2.466AspThr: 2.466 ± 0.019	3.0AspVal: 3.0 ± 0.02	0.638AspTrp: 0.638 ± 0.008	1.504AspTyr: 1.504 ± 0.013	0.0AspXaa: 0.0 ± 0.0
Glu	4.851GluAla: 4.851 ± 0.033	1.242GluCys: 1.242 ± 0.016	4.131GluAsp: 4.131 ± 0.026	7.814GluGlu: 7.814 ± 0.063	2.049GluPhe: 2.049 ± 0.018	4.124GluGly: 4.124 ± 0.03	1.516GluHis: 1.516 ± 0.014	3.354GluIle: 3.354 ± 0.024	5.291GluLys: 5.291 ± 0.041	6.453GluLeu: 6.453 ± 0.049	1.791GluMet: 1.791 ± 0.016	3.249GluAsn: 3.249 ± 0.024	3.066GluPro: 3.066 ± 0.024	3.281GluGln: 3.281 ± 0.024	4.099GluArg: 4.099 ± 0.033	4.567GluSer: 4.567 ± 0.027	3.636GluThr: 3.636 ± 0.025	4.001GluVal: 4.001 ± 0.023	0.709GluTrp: 0.709 ± 0.009	1.639GluTyr: 1.639 ± 0.014	0.0GluXaa: 0.0 ± 0.0
Phe	2.044PheAla: 2.044 ± 0.015	0.934PheCys: 0.934 ± 0.013	1.645PheAsp: 1.645 ± 0.014	1.912PheGlu: 1.912 ± 0.016	1.547PhePhe: 1.547 ± 0.015	2.169PheGly: 2.169 ± 0.018	1.043PheHis: 1.043 ± 0.011	1.866PheIle: 1.866 ± 0.015	1.831PheLys: 1.831 ± 0.016	3.962PheLeu: 3.962 ± 0.027	0.795PheMet: 0.795 ± 0.01	1.381PheAsn: 1.381 ± 0.013	2.022PhePro: 2.022 ± 0.016	1.773PheGln: 1.773 ± 0.016	1.84PheArg: 1.84 ± 0.015	3.293PheSer: 3.293 ± 0.022	2.076PheThr: 2.076 ± 0.017	2.098PheVal: 2.098 ± 0.015	0.488PheTrp: 0.488 ± 0.008	1.2PheTyr: 1.2 ± 0.013	0.0PheXaa: 0.0 ± 0.0
Gly	4.621GlyAla: 4.621 ± 0.033	1.359GlyCys: 1.359 ± 0.014	3.089GlyAsp: 3.089 ± 0.029	4.159GlyGlu: 4.159 ± 0.036	2.376GlyPhe: 2.376 ± 0.018	4.988GlyGly: 4.988 ± 0.043	1.607GlyHis: 1.607 ± 0.015	2.937GlyIle: 2.937 ± 0.019	3.873GlyLys: 3.873 ± 0.025	5.672GlyLeu: 5.672 ± 0.034	1.397GlyMet: 1.397 ± 0.013	2.508GlyAsn: 2.508 ± 0.02	3.554GlyPro: 3.554 ± 0.052	2.778GlyGln: 2.778 ± 0.023	3.781GlyArg: 3.781 ± 0.033	5.739GlySer: 5.739 ± 0.031	3.596GlyThr: 3.596 ± 0.03	3.509GlyVal: 3.509 ± 0.025	0.88GlyTrp: 0.88 ± 0.011	1.825GlyTyr: 1.825 ± 0.016	0.0GlyXaa: 0.0 ± 0.0
His	1.358HisAla: 1.358 ± 0.012	0.739HisCys: 0.739 ± 0.01	0.884HisAsp: 0.884 ± 0.009	1.304HisGlu: 1.304 ± 0.012	1.061HisPhe: 1.061 ± 0.011	1.561HisGly: 1.561 ± 0.013	0.89HisHis: 0.89 ± 0.012	1.243HisIle: 1.243 ± 0.012	1.313HisLys: 1.313 ± 0.012	2.785HisLeu: 2.785 ± 0.019	0.6HisMet: 0.6 ± 0.008	0.938HisAsn: 0.938 ± 0.011	1.644HisPro: 1.644 ± 0.015	1.252HisGln: 1.252 ± 0.013	1.544HisArg: 1.544 ± 0.015	2.258HisSer: 2.258 ± 0.018	1.344HisThr: 1.344 ± 0.015	1.47HisVal: 1.47 ± 0.013	0.372HisTrp: 0.372 ± 0.007	0.836HisTyr: 0.836 ± 0.01	0.0HisXaa: 0.0 ± 0.0
Ile	2.807IleAla: 2.807 ± 0.02	1.152IleCys: 1.152 ± 0.013	2.119IleAsp: 2.119 ± 0.019	2.637IleGlu: 2.637 ± 0.02	1.882IlePhe: 1.882 ± 0.015	2.372IleGly: 2.372 ± 0.016	1.271IleHis: 1.271 ± 0.011	2.44IleIle: 2.44 ± 0.02	2.747IleLys: 2.747 ± 0.022	4.641IleLeu: 4.641 ± 0.032	1.027IleMet: 1.027 ± 0.011	1.967IleAsn: 1.967 ± 0.015	2.72IlePro: 2.72 ± 0.019	2.396IleGln: 2.396 ± 0.016	2.389IleArg: 2.389 ± 0.017	3.969IleSer: 3.969 ± 0.025	2.718IleThr: 2.718 ± 0.021	2.682IleVal: 2.682 ± 0.022	0.542IleTrp: 0.542 ± 0.008	1.446IleTyr: 1.446 ± 0.015	0.0IleXaa: 0.0 ± 0.0
Lys	3.929LysAla: 3.929 ± 0.025	1.178LysCys: 1.178 ± 0.013	3.13LysAsp: 3.13 ± 0.022	5.256LysGlu: 5.256 ± 0.042	1.69LysPhe: 1.69 ± 0.017	3.467LysGly: 3.467 ± 0.033	1.498LysHis: 1.498 ± 0.014	2.885LysIle: 2.885 ± 0.021	4.824LysLys: 4.824 ± 0.041	5.336LysLeu: 5.336 ± 0.033	1.554LysMet: 1.554 ± 0.016	2.512LysAsn: 2.512 ± 0.021	2.986LysPro: 2.986 ± 0.023	2.842LysGln: 2.842 ± 0.019	3.458LysArg: 3.458 ± 0.024	4.063LysSer: 4.063 ± 0.026	3.101LysThr: 3.101 ± 0.02	3.49LysVal: 3.49 ± 0.021	0.643LysTrp: 0.643 ± 0.009	1.641LysTyr: 1.641 ± 0.013	0.0LysXaa: 0.0 ± 0.0
Leu	6.746LeuAla: 6.746 ± 0.033	2.31LeuCys: 2.31 ± 0.021	4.574LeuAsp: 4.574 ± 0.026	6.894LeuGlu: 6.894 ± 0.05	3.365LeuPhe: 3.365 ± 0.025	5.705LeuGly: 5.705 ± 0.03	2.725LeuHis: 2.725 ± 0.019	3.955LeuIle: 3.955 ± 0.025	5.927LeuLys: 5.927 ± 0.034	10.602LeuLeu: 10.602 ± 0.062	2.069LeuMet: 2.069 ± 0.018	3.637LeuAsn: 3.637 ± 0.023	5.91LeuPro: 5.91 ± 0.034	5.743LeuGln: 5.743 ± 0.042	5.564LeuArg: 5.564 ± 0.031	8.005LeuSer: 8.005 ± 0.037	4.986LeuThr: 4.986 ± 0.026	5.39LeuVal: 5.39 ± 0.025	1.15LeuTrp: 1.15 ± 0.012	2.62LeuTyr: 2.62 ± 0.017	0.0LeuXaa: 0.0 ± 0.0
Met	1.963MetAla: 1.963 ± 0.015	0.443MetCys: 0.443 ± 0.007	1.294MetAsp: 1.294 ± 0.014	1.978MetGlu: 1.978 ± 0.016	0.768MetPhe: 0.768 ± 0.009	1.4MetGly: 1.4 ± 0.013	0.518MetHis: 0.518 ± 0.008	0.904MetIle: 0.904 ± 0.009	1.542MetLys: 1.542 ± 0.015	2.06MetLeu: 2.06 ± 0.017	0.608MetMet: 0.608 ± 0.009	0.952MetAsn: 0.952 ± 0.011	1.126MetPro: 1.126 ± 0.014	1.044MetGln: 1.044 ± 0.013	1.087MetArg: 1.087 ± 0.011	1.653MetSer: 1.653 ± 0.013	1.122MetThr: 1.122 ± 0.01	1.408MetVal: 1.408 ± 0.012	0.257MetTrp: 0.257 ± 0.006	0.609MetTyr: 0.609 ± 0.008	0.0MetXaa: 0.0 ± 0.0
Asn	2.216AsnAla: 2.216 ± 0.016	0.927AsnCys: 0.927 ± 0.012	1.547AsnAsp: 1.547 ± 0.015	2.397AsnGlu: 2.397 ± 0.017	1.465AsnPhe: 1.465 ± 0.014	2.635AsnGly: 2.635 ± 0.021	0.957AsnHis: 0.957 ± 0.01	2.266AsnIle: 2.266 ± 0.017	2.363AsnLys: 2.363 ± 0.018	3.787AsnLeu: 3.787 ± 0.022	0.986AsnMet: 0.986 ± 0.01	1.708AsnAsn: 1.708 ± 0.016	2.208AsnPro: 2.208 ± 0.019	1.722AsnGln: 1.722 ± 0.016	1.944AsnArg: 1.944 ± 0.015	3.294AsnSer: 3.294 ± 0.023	2.101AsnThr: 2.101 ± 0.017	2.343AsnVal: 2.343 ± 0.019	0.472AsnTrp: 0.472 ± 0.008	1.174AsnTyr: 1.174 ± 0.013	0.0AsnXaa: 0.0 ± 0.0
Pro	4.891ProAla: 4.891 ± 0.036	1.214ProCys: 1.214 ± 0.018	2.641ProAsp: 2.641 ± 0.022	4.07ProGlu: 4.07 ± 0.028	1.913ProPhe: 1.913 ± 0.017	4.834ProGly: 4.834 ± 0.063	1.432ProHis: 1.432 ± 0.015	1.984ProIle: 1.984 ± 0.016	2.757ProLys: 2.757 ± 0.033	5.132ProLeu: 5.132 ± 0.032	1.04ProMet: 1.04 ± 0.011	1.858ProAsn: 1.858 ± 0.016	5.438ProPro: 5.438 ± 0.057	2.633ProGln: 2.633 ± 0.024	3.1ProArg: 3.1 ± 0.026	5.348ProSer: 5.348 ± 0.039	2.868ProThr: 2.868 ± 0.028	3.747ProVal: 3.747 ± 0.024	0.695ProTrp: 0.695 ± 0.01	1.397ProTyr: 1.397 ± 0.013	0.0ProXaa: 0.0 ± 0.0
Gln	3.326GlnAla: 3.326 ± 0.023	0.982GlnCys: 0.982 ± 0.016	2.233GlnAsp: 2.233 ± 0.016	3.867GlnGlu: 3.867 ± 0.031	1.385GlnPhe: 1.385 ± 0.012	2.829GlnGly: 2.829 ± 0.024	1.365GlnHis: 1.365 ± 0.013	2.104GlnIle: 2.104 ± 0.017	2.984GlnLys: 2.984 ± 0.025	4.767GlnLeu: 4.767 ± 0.031	1.143GlnMet: 1.143 ± 0.011	1.973GlnAsn: 1.973 ± 0.018	2.725GlnPro: 2.725 ± 0.024	3.166GlnGln: 3.166 ± 0.044	2.929GlnArg: 2.929 ± 0.022	3.291GlnSer: 3.291 ± 0.025	2.402GlnThr: 2.402 ± 0.017	2.699GlnVal: 2.699 ± 0.019	0.556GlnTrp: 0.556 ± 0.007	1.215GlnTyr: 1.215 ± 0.012	0.0GlnXaa: 0.0 ± 0.0
Arg	3.785ArgAla: 3.785 ± 0.026	1.234ArgCys: 1.234 ± 0.017	2.695ArgAsp: 2.695 ± 0.018	3.936ArgGlu: 3.936 ± 0.031	1.847ArgPhe: 1.847 ± 0.015	3.616ArgGly: 3.616 ± 0.032	1.466ArgHis: 1.466 ± 0.014	2.474ArgIle: 2.474 ± 0.017	3.711ArgLys: 3.711 ± 0.024	5.206ArgLeu: 5.206 ± 0.025	1.245ArgMet: 1.245 ± 0.014	2.146ArgAsn: 2.146 ± 0.016	2.918ArgPro: 2.918 ± 0.025	2.588ArgGln: 2.588 ± 0.022	4.202ArgArg: 4.202 ± 0.033	4.231ArgSer: 4.231 ± 0.033	2.767ArgThr: 2.767 ± 0.019	3.023ArgVal: 3.023 ± 0.019	0.709ArgTrp: 0.709 ± 0.009	1.516ArgTyr: 1.516 ± 0.016	0.0ArgXaa: 0.0 ± 0.0
Ser	5.483SerAla: 5.483 ± 0.031	1.985SerCys: 1.985 ± 0.019	3.881SerAsp: 3.881 ± 0.024	5.169SerGlu: 5.169 ± 0.028	2.988SerPhe: 2.988 ± 0.018	5.356SerGly: 5.356 ± 0.034	2.095SerHis: 2.095 ± 0.015	3.442SerIle: 3.442 ± 0.019	4.28SerLys: 4.28 ± 0.028	8.206SerLeu: 8.206 ± 0.034	1.737SerMet: 1.737 ± 0.015	2.905SerAsn: 2.905 ± 0.021	5.865SerPro: 5.865 ± 0.041	3.862SerGln: 3.862 ± 0.026	4.42SerArg: 4.42 ± 0.031	9.333SerSer: 9.333 ± 0.066	4.547SerThr: 4.547 ± 0.048	4.906SerVal: 4.906 ± 0.026	1.045SerTrp: 1.045 ± 0.011	2.156SerTyr: 2.156 ± 0.018	0.0SerXaa: 0.0 ± 0.0
Thr	3.934ThrAla: 3.934 ± 0.026	1.329ThrCys: 1.329 ± 0.02	2.617ThrAsp: 2.617 ± 0.02	3.658ThrGlu: 3.658 ± 0.026	2.073ThrPhe: 2.073 ± 0.017	3.527ThrGly: 3.527 ± 0.027	1.232ThrHis: 1.232 ± 0.013	2.499ThrIle: 2.499 ± 0.02	2.738ThrLys: 2.738 ± 0.019	5.189ThrLeu: 5.189 ± 0.028	1.167ThrMet: 1.167 ± 0.013	1.891ThrAsn: 1.891 ± 0.015	3.335ThrPro: 3.335 ± 0.043	2.239ThrGln: 2.239 ± 0.017	2.419ThrArg: 2.419 ± 0.018	4.628ThrSer: 4.628 ± 0.035	3.085ThrThr: 3.085 ± 0.066	3.838ThrVal: 3.838 ± 0.026	0.676ThrTrp: 0.676 ± 0.01	1.455ThrTyr: 1.455 ± 0.012	0.0ThrXaa: 0.0 ± 0.0
Val	4.099ValAla: 4.099 ± 0.025	1.502ValCys: 1.502 ± 0.014	2.776ValAsp: 2.776 ± 0.021	3.789ValGlu: 3.789 ± 0.022	2.362ValPhe: 2.362 ± 0.02	3.324ValGly: 3.324 ± 0.023	1.507ValHis: 1.507 ± 0.013	2.928ValIle: 2.928 ± 0.021	3.49ValLys: 3.49 ± 0.025	6.105ValLeu: 6.105 ± 0.029	1.38ValMet: 1.38 ± 0.01	2.34ValAsn: 2.34 ± 0.016	3.473ValPro: 3.473 ± 0.024	2.785ValGln: 2.785 ± 0.022	2.967ValArg: 2.967 ± 0.021	4.984ValSer: 4.984 ± 0.029	3.776ValThr: 3.776 ± 0.024	3.822ValVal: 3.822 ± 0.027	0.727ValTrp: 0.727 ± 0.01	1.693ValTyr: 1.693 ± 0.016	0.0ValXaa: 0.0 ± 0.0
Trp	0.804TrpAla: 0.804 ± 0.01	0.263TrpCys: 0.263 ± 0.005	0.665TrpAsp: 0.665 ± 0.01	0.817TrpGlu: 0.817 ± 0.011	0.445TrpPhe: 0.445 ± 0.007	0.817TrpGly: 0.817 ± 0.011	0.318TrpHis: 0.318 ± 0.006	0.605TrpIle: 0.605 ± 0.008	0.835TrpLys: 0.835 ± 0.01	1.268TrpLeu: 1.268 ± 0.014	0.33TrpMet: 0.33 ± 0.006	0.549TrpAsn: 0.549 ± 0.008	0.506TrpPro: 0.506 ± 0.007	0.558TrpGln: 0.558 ± 0.01	0.749TrpArg: 0.749 ± 0.009	0.876TrpSer: 0.876 ± 0.011	0.636TrpThr: 0.636 ± 0.009	0.706TrpVal: 0.706 ± 0.009	0.196TrpTrp: 0.196 ± 0.005	0.358TrpTyr: 0.358 ± 0.007	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.473TyrAla: 1.473 ± 0.013	0.743TyrCys: 0.743 ± 0.01	1.316TyrAsp: 1.316 ± 0.014	1.638TyrGlu: 1.638 ± 0.014	1.257TyrPhe: 1.257 ± 0.014	1.708TyrGly: 1.708 ± 0.017	0.746TyrHis: 0.746 ± 0.009	1.463TyrIle: 1.463 ± 0.014	1.536TyrLys: 1.536 ± 0.015	2.707TyrLeu: 2.707 ± 0.019	0.651TyrMet: 0.651 ± 0.007	1.192TyrAsn: 1.192 ± 0.012	1.351TyrPro: 1.351 ± 0.013	1.275TyrGln: 1.275 ± 0.013	1.612TyrArg: 1.612 ± 0.016	2.286TyrSer: 2.286 ± 0.017	1.53TyrThr: 1.53 ± 0.015	1.579TyrVal: 1.579 ± 0.012	0.395TyrTrp: 0.395 ± 0.008	1.01TyrTyr: 1.01 ± 0.011	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.016XaaXaa: 0.016 ± 0.01

Statistics based on 21371 proteins (10016199 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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