Amino acid dipepetide frequency for Zygotorulaspora mrakii (Zygosaccharomyces mrakii)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	4.287AlaAla: 4.287 ± 0.062	0.745AlaCys: 0.745 ± 0.019	2.881AlaAsp: 2.881 ± 0.035	3.436AlaGlu: 3.436 ± 0.044	2.396AlaPhe: 2.396 ± 0.038	3.219AlaGly: 3.219 ± 0.049	1.17AlaHis: 1.17 ± 0.024	3.706AlaIle: 3.706 ± 0.045	4.027AlaLys: 4.027 ± 0.045	5.659AlaLeu: 5.659 ± 0.047	1.319AlaMet: 1.319 ± 0.021	2.98AlaAsn: 2.98 ± 0.038	2.368AlaPro: 2.368 ± 0.052	2.368AlaGln: 2.368 ± 0.052	2.677AlaArg: 2.677 ± 0.039	5.235AlaSer: 5.235 ± 0.065	3.602AlaThr: 3.602 ± 0.055	3.517AlaVal: 3.517 ± 0.04	0.528AlaTrp: 0.528 ± 0.016	1.747AlaTyr: 1.747 ± 0.029	0.0AlaXaa: 0.0 ± 0.0
Cys	0.683CysAla: 0.683 ± 0.018	0.297CysCys: 0.297 ± 0.014	0.745CysAsp: 0.745 ± 0.018	0.702CysGlu: 0.702 ± 0.018	0.695CysPhe: 0.695 ± 0.017	0.907CysGly: 0.907 ± 0.022	0.339CysHis: 0.339 ± 0.011	0.97CysIle: 0.97 ± 0.023	0.765CysLys: 0.765 ± 0.021	1.375CysLeu: 1.375 ± 0.028	0.26CysMet: 0.26 ± 0.011	0.667CysAsn: 0.667 ± 0.019	0.525CysPro: 0.525 ± 0.017	0.453CysGln: 0.453 ± 0.014	0.588CysArg: 0.588 ± 0.016	1.173CysSer: 1.173 ± 0.026	0.644CysThr: 0.644 ± 0.018	0.822CysVal: 0.822 ± 0.022	0.165CysTrp: 0.165 ± 0.008	0.502CysTyr: 0.502 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	3.273AspAla: 3.273 ± 0.037	0.705AspCys: 0.705 ± 0.018	4.549AspAsp: 4.549 ± 0.073	4.982AspGlu: 4.982 ± 0.061	2.778AspPhe: 2.778 ± 0.033	3.066AspGly: 3.066 ± 0.04	1.15AspHis: 1.15 ± 0.023	4.16AspIle: 4.16 ± 0.042	3.426AspLys: 3.426 ± 0.037	5.557AspLeu: 5.557 ± 0.047	1.234AspMet: 1.234 ± 0.021	2.954AspAsn: 2.954 ± 0.039	2.423AspPro: 2.423 ± 0.034	1.925AspGln: 1.925 ± 0.026	2.235AspArg: 2.235 ± 0.031	5.075AspSer: 5.075 ± 0.052	2.886AspThr: 2.886 ± 0.037	3.557AspVal: 3.557 ± 0.046	0.628AspTrp: 0.628 ± 0.015	2.136AspTyr: 2.136 ± 0.031	0.0AspXaa: 0.0 ± 0.0
Glu	3.637GluAla: 3.637 ± 0.044	0.735GluCys: 0.735 ± 0.018	4.411GluAsp: 4.411 ± 0.058	5.99GluGlu: 5.99 ± 0.083	2.721GluPhe: 2.721 ± 0.035	2.915GluGly: 2.915 ± 0.037	1.329GluHis: 1.329 ± 0.025	4.376GluIle: 4.376 ± 0.043	5.274GluLys: 5.274 ± 0.063	6.5GluLeu: 6.5 ± 0.06	1.489GluMet: 1.489 ± 0.022	4.232GluAsn: 4.232 ± 0.047	2.021GluPro: 2.021 ± 0.03	2.805GluGln: 2.805 ± 0.039	3.268GluArg: 3.268 ± 0.04	5.215GluSer: 5.215 ± 0.052	3.715GluThr: 3.715 ± 0.045	3.601GluVal: 3.601 ± 0.041	0.64GluTrp: 0.64 ± 0.015	2.256GluTyr: 2.256 ± 0.032	0.0GluXaa: 0.0 ± 0.0
Phe	2.546PheAla: 2.546 ± 0.037	0.601PheCys: 0.601 ± 0.016	2.753PheAsp: 2.753 ± 0.035	2.959PheGlu: 2.959 ± 0.04	2.175PhePhe: 2.175 ± 0.038	2.664PheGly: 2.664 ± 0.046	1.017PheHis: 1.017 ± 0.023	2.784PheIle: 2.784 ± 0.039	2.975PheLys: 2.975 ± 0.039	4.199PheLeu: 4.199 ± 0.047	0.903PheMet: 0.903 ± 0.021	2.389PheAsn: 2.389 ± 0.034	1.766PhePro: 1.766 ± 0.026	1.851PheGln: 1.851 ± 0.029	1.689PheArg: 1.689 ± 0.025	3.762PheSer: 3.762 ± 0.04	2.47PheThr: 2.47 ± 0.042	2.656PheVal: 2.656 ± 0.036	0.506PheTrp: 0.506 ± 0.016	1.553PheTyr: 1.553 ± 0.026	0.0PheXaa: 0.0 ± 0.0
Gly	3.107GlyAla: 3.107 ± 0.047	0.777GlyCys: 0.777 ± 0.021	2.862GlyAsp: 2.862 ± 0.039	3.032GlyGlu: 3.032 ± 0.037	2.488GlyPhe: 2.488 ± 0.032	3.492GlyGly: 3.492 ± 0.056	1.195GlyHis: 1.195 ± 0.024	3.678GlyIle: 3.678 ± 0.046	3.751GlyLys: 3.751 ± 0.041	4.814GlyLeu: 4.814 ± 0.054	1.061GlyMet: 1.061 ± 0.022	2.998GlyAsn: 2.998 ± 0.043	1.7GlyPro: 1.7 ± 0.032	1.762GlyGln: 1.762 ± 0.03	2.33GlyArg: 2.33 ± 0.035	5.208GlySer: 5.208 ± 0.076	3.174GlyThr: 3.174 ± 0.047	3.216GlyVal: 3.216 ± 0.037	0.596GlyTrp: 0.596 ± 0.017	1.851GlyTyr: 1.851 ± 0.032	0.0GlyXaa: 0.0 ± 0.0
His	1.09HisAla: 1.09 ± 0.022	0.351HisCys: 0.351 ± 0.012	1.231HisAsp: 1.231 ± 0.022	1.376HisGlu: 1.376 ± 0.027	1.013HisPhe: 1.013 ± 0.023	1.249HisGly: 1.249 ± 0.026	0.649HisHis: 0.649 ± 0.021	1.4HisIle: 1.4 ± 0.022	1.252HisLys: 1.252 ± 0.022	2.176HisLeu: 2.176 ± 0.034	0.437HisMet: 0.437 ± 0.012	1.074HisAsn: 1.074 ± 0.022	1.035HisPro: 1.035 ± 0.02	0.904HisGln: 0.904 ± 0.023	1.091HisArg: 1.091 ± 0.021	1.973HisSer: 1.973 ± 0.036	1.064HisThr: 1.064 ± 0.022	1.23HisVal: 1.23 ± 0.025	0.246HisTrp: 0.246 ± 0.01	0.811HisTyr: 0.811 ± 0.018	0.0HisXaa: 0.0 ± 0.0
Ile	3.844IleAla: 3.844 ± 0.045	0.998IleCys: 0.998 ± 0.021	3.959IleAsp: 3.959 ± 0.042	4.057IleGlu: 4.057 ± 0.046	2.845IlePhe: 2.845 ± 0.041	3.197IleGly: 3.197 ± 0.041	1.372IleHis: 1.372 ± 0.023	3.866IleIle: 3.866 ± 0.044	4.183IleLys: 4.183 ± 0.048	6.018IleLeu: 6.018 ± 0.049	1.338IleMet: 1.338 ± 0.024	3.324IleAsn: 3.324 ± 0.04	3.147IlePro: 3.147 ± 0.04	2.297IleGln: 2.297 ± 0.031	2.831IleArg: 2.831 ± 0.036	5.895IleSer: 5.895 ± 0.053	3.439IleThr: 3.439 ± 0.045	3.888IleVal: 3.888 ± 0.042	0.709IleTrp: 0.709 ± 0.019	2.03IleTyr: 2.03 ± 0.031	0.0IleXaa: 0.0 ± 0.0
Lys	3.588LysAla: 3.588 ± 0.04	0.847LysCys: 0.847 ± 0.019	3.927LysAsp: 3.927 ± 0.041	5.069LysGlu: 5.069 ± 0.059	2.969LysPhe: 2.969 ± 0.033	3.005LysGly: 3.005 ± 0.04	1.468LysHis: 1.468 ± 0.026	4.457LysIle: 4.457 ± 0.042	6.143LysLys: 6.143 ± 0.078	6.873LysLeu: 6.873 ± 0.063	1.534LysMet: 1.534 ± 0.026	4.202LysAsn: 4.202 ± 0.046	2.617LysPro: 2.617 ± 0.035	2.759LysGln: 2.759 ± 0.038	4.065LysArg: 4.065 ± 0.047	5.676LysSer: 5.676 ± 0.053	3.686LysThr: 3.686 ± 0.044	3.957LysVal: 3.957 ± 0.039	0.793LysTrp: 0.793 ± 0.019	2.53LysTyr: 2.53 ± 0.032	0.0LysXaa: 0.0 ± 0.0
Leu	5.555LeuAla: 5.555 ± 0.052	1.367LeuCys: 1.367 ± 0.026	5.4LeuAsp: 5.4 ± 0.048	6.32LeuGlu: 6.32 ± 0.066	4.098LeuPhe: 4.098 ± 0.057	4.649LeuGly: 4.649 ± 0.05	2.085LeuHis: 2.085 ± 0.035	5.584LeuIle: 5.584 ± 0.054	7.437LeuLys: 7.437 ± 0.068	9.738LeuLeu: 9.738 ± 0.097	2.009LeuMet: 2.009 ± 0.03	5.411LeuAsn: 5.411 ± 0.054	4.548LeuPro: 4.548 ± 0.043	4.357LeuGln: 4.357 ± 0.045	4.837LeuArg: 4.837 ± 0.055	8.416LeuSer: 8.416 ± 0.07	5.034LeuThr: 5.034 ± 0.053	5.215LeuVal: 5.215 ± 0.051	0.908LeuTrp: 0.908 ± 0.019	3.065LeuTyr: 3.065 ± 0.042	0.0LeuXaa: 0.0 ± 0.0
Met	1.394MetAla: 1.394 ± 0.027	0.292MetCys: 0.292 ± 0.012	1.281MetAsp: 1.281 ± 0.025	1.337MetGlu: 1.337 ± 0.022	0.884MetPhe: 0.884 ± 0.018	1.179MetGly: 1.179 ± 0.022	0.38MetHis: 0.38 ± 0.013	1.306MetIle: 1.306 ± 0.022	1.524MetLys: 1.524 ± 0.027	1.929MetLeu: 1.929 ± 0.022	0.519MetMet: 0.519 ± 0.016	1.257MetAsn: 1.257 ± 0.026	0.853MetPro: 0.853 ± 0.021	0.757MetGln: 0.757 ± 0.02	0.968MetArg: 0.968 ± 0.019	2.075MetSer: 2.075 ± 0.033	1.181MetThr: 1.181 ± 0.024	1.239MetVal: 1.239 ± 0.023	0.197MetTrp: 0.197 ± 0.01	0.587MetTyr: 0.587 ± 0.016	0.0MetXaa: 0.0 ± 0.0
Asn	3.277AsnAla: 3.277 ± 0.034	0.698AsnCys: 0.698 ± 0.019	3.695AsnAsp: 3.695 ± 0.049	4.049AsnGlu: 4.049 ± 0.046	2.404AsnPhe: 2.404 ± 0.033	3.494AsnGly: 3.494 ± 0.045	1.175AsnHis: 1.175 ± 0.024	3.498AsnIle: 3.498 ± 0.041	3.512AsnLys: 3.512 ± 0.044	4.818AsnLeu: 4.818 ± 0.049	1.205AsnMet: 1.205 ± 0.022	3.498AsnAsn: 3.498 ± 0.066	2.301AsnPro: 2.301 ± 0.03	1.932AsnGln: 1.932 ± 0.032	2.307AsnArg: 2.307 ± 0.032	5.265AsnSer: 5.265 ± 0.059	2.964AsnThr: 2.964 ± 0.035	3.285AsnVal: 3.285 ± 0.041	0.611AsnTrp: 0.611 ± 0.017	1.858AsnTyr: 1.858 ± 0.03	0.0AsnXaa: 0.0 ± 0.0
Pro	2.321ProAla: 2.321 ± 0.039	0.399ProCys: 0.399 ± 0.015	2.155ProAsp: 2.155 ± 0.029	2.851ProGlu: 2.851 ± 0.04	1.896ProPhe: 1.896 ± 0.034	1.988ProGly: 1.988 ± 0.034	0.96ProHis: 0.96 ± 0.019	2.603ProIle: 2.603 ± 0.038	2.702ProLys: 2.702 ± 0.034	4.066ProLeu: 4.066 ± 0.043	0.813ProMet: 0.813 ± 0.021	2.188ProAsn: 2.188 ± 0.033	2.208ProPro: 2.208 ± 0.051	1.92ProGln: 1.92 ± 0.039	1.78ProArg: 1.78 ± 0.03	4.027ProSer: 4.027 ± 0.059	2.533ProThr: 2.533 ± 0.038	2.651ProVal: 2.651 ± 0.04	0.456ProTrp: 0.456 ± 0.021	1.316ProTyr: 1.316 ± 0.025	0.0ProXaa: 0.0 ± 0.0
Gln	2.18GlnAla: 2.18 ± 0.051	0.447GlnCys: 0.447 ± 0.013	2.181GlnAsp: 2.181 ± 0.032	2.847GlnGlu: 2.847 ± 0.037	1.71GlnPhe: 1.71 ± 0.028	1.82GlnGly: 1.82 ± 0.029	0.931GlnHis: 0.931 ± 0.023	2.395GlnIle: 2.395 ± 0.033	2.705GlnLys: 2.705 ± 0.037	4.183GlnLeu: 4.183 ± 0.048	0.871GlnMet: 0.871 ± 0.019	2.29GlnAsn: 2.29 ± 0.029	1.625GlnPro: 1.625 ± 0.041	3.146GlnGln: 3.146 ± 0.156	2.121GlnArg: 2.121 ± 0.031	3.158GlnSer: 3.158 ± 0.045	2.013GlnThr: 2.013 ± 0.034	2.162GlnVal: 2.162 ± 0.028	0.414GlnTrp: 0.414 ± 0.015	1.343GlnTyr: 1.343 ± 0.023	0.0GlnXaa: 0.0 ± 0.0
Arg	2.556ArgAla: 2.556 ± 0.034	0.656ArgCys: 0.656 ± 0.017	2.654ArgAsp: 2.654 ± 0.031	3.091ArgGlu: 3.091 ± 0.038	2.033ArgPhe: 2.033 ± 0.027	2.352ArgGly: 2.352 ± 0.04	1.023ArgHis: 1.023 ± 0.021	3.03ArgIle: 3.03 ± 0.036	3.791ArgLys: 3.791 ± 0.044	4.423ArgLeu: 4.423 ± 0.047	1.002ArgMet: 1.002 ± 0.019	2.651ArgAsn: 2.651 ± 0.033	1.751ArgPro: 1.751 ± 0.028	1.897ArgGln: 1.897 ± 0.031	2.99ArgArg: 2.99 ± 0.044	3.99ArgSer: 3.99 ± 0.047	2.438ArgThr: 2.438 ± 0.033	2.518ArgVal: 2.518 ± 0.034	0.507ArgTrp: 0.507 ± 0.014	1.635ArgTyr: 1.635 ± 0.025	0.0ArgXaa: 0.0 ± 0.0
Ser	5.022SerAla: 5.022 ± 0.058	1.077SerCys: 1.077 ± 0.023	4.837SerAsp: 4.837 ± 0.047	5.128SerGlu: 5.128 ± 0.053	3.994SerPhe: 3.994 ± 0.046	4.972SerGly: 4.972 ± 0.059	2.003SerHis: 2.003 ± 0.031	5.618SerIle: 5.618 ± 0.052	6.278SerLys: 6.278 ± 0.055	8.614SerLeu: 8.614 ± 0.07	1.859SerMet: 1.859 ± 0.031	5.321SerAsn: 5.321 ± 0.063	3.736SerPro: 3.736 ± 0.062	3.594SerGln: 3.594 ± 0.042	4.144SerArg: 4.144 ± 0.044	10.56SerSer: 10.56 ± 0.165	5.645SerThr: 5.645 ± 0.107	4.971SerVal: 4.971 ± 0.045	0.861SerTrp: 0.861 ± 0.02	2.65SerTyr: 2.65 ± 0.041	0.0SerXaa: 0.0 ± 0.0
Thr	3.466ThrAla: 3.466 ± 0.048	0.7ThrCys: 0.7 ± 0.018	2.846ThrAsp: 2.846 ± 0.032	3.26ThrGlu: 3.26 ± 0.038	2.417ThrPhe: 2.417 ± 0.038	3.301ThrGly: 3.301 ± 0.058	1.138ThrHis: 1.138 ± 0.023	3.584ThrIle: 3.584 ± 0.053	3.609ThrLys: 3.609 ± 0.044	5.274ThrLeu: 5.274 ± 0.053	1.148ThrMet: 1.148 ± 0.025	3.047ThrAsn: 3.047 ± 0.037	2.785ThrPro: 2.785 ± 0.048	1.915ThrGln: 1.915 ± 0.029	2.413ThrArg: 2.413 ± 0.035	5.37ThrSer: 5.37 ± 0.093	3.547ThrThr: 3.547 ± 0.088	3.558ThrVal: 3.558 ± 0.05	0.567ThrTrp: 0.567 ± 0.015	1.645ThrTyr: 1.645 ± 0.036	0.0ThrXaa: 0.0 ± 0.0
Val	3.652ValAla: 3.652 ± 0.04	0.812ValCys: 0.812 ± 0.019	3.595ValAsp: 3.595 ± 0.042	3.927ValGlu: 3.927 ± 0.039	2.591ValPhe: 2.591 ± 0.041	3.106ValGly: 3.106 ± 0.039	1.199ValHis: 1.199 ± 0.023	3.605ValIle: 3.605 ± 0.041	3.87ValLys: 3.87 ± 0.044	5.557ValLeu: 5.557 ± 0.052	1.17ValMet: 1.17 ± 0.021	3.003ValAsn: 3.003 ± 0.035	2.829ValPro: 2.829 ± 0.034	2.114ValGln: 2.114 ± 0.028	2.568ValArg: 2.568 ± 0.033	5.17ValSer: 5.17 ± 0.056	3.302ValThr: 3.302 ± 0.047	3.637ValVal: 3.637 ± 0.039	0.598ValTrp: 0.598 ± 0.014	1.883ValTyr: 1.883 ± 0.028	0.0ValXaa: 0.0 ± 0.0
Trp	0.535TrpAla: 0.535 ± 0.017	0.242TrpCys: 0.242 ± 0.011	0.671TrpAsp: 0.671 ± 0.017	0.614TrpGlu: 0.614 ± 0.015	0.502TrpPhe: 0.502 ± 0.015	0.529TrpGly: 0.529 ± 0.015	0.229TrpHis: 0.229 ± 0.011	0.653TrpIle: 0.653 ± 0.019	0.851TrpLys: 0.851 ± 0.019	0.996TrpLeu: 0.996 ± 0.022	0.224TrpMet: 0.224 ± 0.011	0.629TrpAsn: 0.629 ± 0.015	0.317TrpPro: 0.317 ± 0.012	0.403TrpGln: 0.403 ± 0.012	0.553TrpArg: 0.553 ± 0.016	0.902TrpSer: 0.902 ± 0.021	0.535TrpThr: 0.535 ± 0.021	0.543TrpVal: 0.543 ± 0.016	0.153TrpTrp: 0.153 ± 0.008	0.386TrpTyr: 0.386 ± 0.013	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.856TyrAla: 1.856 ± 0.028	0.533TyrCys: 0.533 ± 0.013	2.065TyrAsp: 2.065 ± 0.026	2.103TyrGlu: 2.103 ± 0.034	1.608TyrPhe: 1.608 ± 0.027	1.984TyrGly: 1.984 ± 0.038	0.843TyrHis: 0.843 ± 0.018	1.964TyrIle: 1.964 ± 0.029	2.092TyrLys: 2.092 ± 0.03	3.264TyrLeu: 3.264 ± 0.043	0.742TyrMet: 0.742 ± 0.017	1.731TyrAsn: 1.731 ± 0.029	1.279TyrPro: 1.279 ± 0.023	1.385TyrGln: 1.385 ± 0.024	1.53TyrArg: 1.53 ± 0.028	2.74TyrSer: 2.74 ± 0.038	1.716TyrThr: 1.716 ± 0.041	1.965TyrVal: 1.965 ± 0.038	0.385TyrTrp: 0.385 ± 0.013	1.361TyrTyr: 1.361 ± 0.031	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5020 proteins (2512296 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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