Amino acid dipepetide frequency for Tortoise microvirus 108

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.454AlaAla: 4.454 ± 1.288
1.114AlaCys: 1.114 ± 0.52
3.341AlaAsp: 3.341 ± 1.578
5.011AlaGlu: 5.011 ± 1.653
4.454AlaPhe: 4.454 ± 1.538
5.011AlaGly: 5.011 ± 1.827
0.557AlaHis: 0.557 ± 0.569
2.784AlaIle: 2.784 ± 0.948
5.568AlaLys: 5.568 ± 1.553
7.795AlaLeu: 7.795 ± 1.326
2.784AlaMet: 2.784 ± 1.711
3.898AlaAsn: 3.898 ± 2.878
4.454AlaPro: 4.454 ± 1.59
2.227AlaGln: 2.227 ± 1.046
1.114AlaArg: 1.114 ± 0.712
7.795AlaSer: 7.795 ± 0.894
3.898AlaThr: 3.898 ± 0.801
3.898AlaVal: 3.898 ± 1.152
0.0AlaTrp: 0.0 ± 0.0
3.898AlaTyr: 3.898 ± 1.359
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
1.114CysCys: 1.114 ± 1.138
1.67CysAsp: 1.67 ± 0.955
0.0CysGlu: 0.0 ± 0.0
2.227CysPhe: 2.227 ± 1.825
0.557CysGly: 0.557 ± 0.569
1.114CysHis: 1.114 ± 0.855
0.0CysIle: 0.0 ± 0.0
1.67CysLys: 1.67 ± 1.377
2.227CysLeu: 2.227 ± 1.531
0.557CysMet: 0.557 ± 0.569
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.557CysGln: 0.557 ± 0.392
1.67CysArg: 1.67 ± 0.869
0.557CysSer: 0.557 ± 0.569
1.114CysThr: 1.114 ± 0.712
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.557CysTyr: 0.557 ± 0.569
0.0CysXaa: 0.0 ± 0.0
Asp
5.568AspAla: 5.568 ± 2.168
2.784AspCys: 2.784 ± 1.081
6.125AspAsp: 6.125 ± 1.978
3.898AspGlu: 3.898 ± 1.313
3.898AspPhe: 3.898 ± 1.545
2.784AspGly: 2.784 ± 1.351
0.557AspHis: 0.557 ± 0.67
5.568AspIle: 5.568 ± 2.441
2.227AspLys: 2.227 ± 0.911
2.784AspLeu: 2.784 ± 0.977
1.114AspMet: 1.114 ± 0.811
2.227AspAsn: 2.227 ± 0.82
1.67AspPro: 1.67 ± 0.728
1.67AspGln: 1.67 ± 0.989
2.784AspArg: 2.784 ± 0.723
2.227AspSer: 2.227 ± 1.04
5.568AspThr: 5.568 ± 1.985
1.67AspVal: 1.67 ± 1.377
0.557AspTrp: 0.557 ± 0.569
4.454AspTyr: 4.454 ± 1.559
0.0AspXaa: 0.0 ± 0.0
Glu
5.568GluAla: 5.568 ± 2.454
0.557GluCys: 0.557 ± 0.844
0.0GluAsp: 0.0 ± 0.0
1.114GluGlu: 1.114 ± 1.0
1.67GluPhe: 1.67 ± 1.508
0.0GluGly: 0.0 ± 0.0
0.557GluHis: 0.557 ± 0.788
1.67GluIle: 1.67 ± 1.226
2.227GluLys: 2.227 ± 1.294
11.136GluLeu: 11.136 ± 1.581
0.557GluMet: 0.557 ± 0.729
1.67GluAsn: 1.67 ± 0.862
2.227GluPro: 2.227 ± 1.268
1.114GluGln: 1.114 ± 1.0
3.341GluArg: 3.341 ± 1.079
3.898GluSer: 3.898 ± 2.322
4.454GluThr: 4.454 ± 1.154
3.898GluVal: 3.898 ± 1.832
0.0GluTrp: 0.0 ± 0.0
1.114GluTyr: 1.114 ± 1.003
0.0GluXaa: 0.0 ± 0.0
Phe
5.011PheAla: 5.011 ± 1.432
0.557PheCys: 0.557 ± 0.569
5.568PheAsp: 5.568 ± 2.937
2.784PheGlu: 2.784 ± 1.107
3.341PhePhe: 3.341 ± 1.407
3.898PheGly: 3.898 ± 1.21
0.557PheHis: 0.557 ± 0.788
1.67PheIle: 1.67 ± 0.955
2.784PheLys: 2.784 ± 0.769
2.784PheLeu: 2.784 ± 1.429
2.227PheMet: 2.227 ± 1.519
3.898PheAsn: 3.898 ± 1.838
3.341PhePro: 3.341 ± 0.719
1.67PheGln: 1.67 ± 0.736
2.227PheArg: 2.227 ± 1.024
2.784PheSer: 2.784 ± 0.992
3.341PheThr: 3.341 ± 1.407
3.898PheVal: 3.898 ± 1.29
0.557PheTrp: 0.557 ± 0.844
3.341PheTyr: 3.341 ± 1.062
0.0PheXaa: 0.0 ± 0.0
Gly
3.898GlyAla: 3.898 ± 2.476
0.557GlyCys: 0.557 ± 0.392
2.227GlyAsp: 2.227 ± 1.303
2.784GlyGlu: 2.784 ± 1.394
4.454GlyPhe: 4.454 ± 1.686
2.227GlyGly: 2.227 ± 1.441
1.67GlyHis: 1.67 ± 1.149
2.784GlyIle: 2.784 ± 1.049
2.784GlyLys: 2.784 ± 0.977
4.454GlyLeu: 4.454 ± 1.858
1.114GlyMet: 1.114 ± 0.786
2.784GlyAsn: 2.784 ± 1.59
0.557GlyPro: 0.557 ± 0.392
1.67GlyGln: 1.67 ± 0.792
3.341GlyArg: 3.341 ± 1.007
9.465GlySer: 9.465 ± 2.643
5.011GlyThr: 5.011 ± 2.919
3.341GlyVal: 3.341 ± 1.072
0.0GlyTrp: 0.0 ± 0.0
4.454GlyTyr: 4.454 ± 0.896
0.0GlyXaa: 0.0 ± 0.0
His
2.227HisAla: 2.227 ± 1.04
0.557HisCys: 0.557 ± 0.569
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
1.114HisPhe: 1.114 ± 0.93
2.227HisGly: 2.227 ± 1.519
0.557HisHis: 0.557 ± 0.569
0.557HisIle: 0.557 ± 0.392
0.557HisLys: 0.557 ± 0.67
1.67HisLeu: 1.67 ± 0.792
0.557HisMet: 0.557 ± 0.844
0.0HisAsn: 0.0 ± 0.0
1.114HisPro: 1.114 ± 1.236
0.0HisGln: 0.0 ± 0.0
1.114HisArg: 1.114 ± 0.76
3.341HisSer: 3.341 ± 1.301
0.0HisThr: 0.0 ± 0.0
0.0HisVal: 0.0 ± 0.0
0.557HisTrp: 0.557 ± 0.569
1.114HisTyr: 1.114 ± 1.025
0.0HisXaa: 0.0 ± 0.0
Ile
2.784IleAla: 2.784 ± 1.537
0.0IleCys: 0.0 ± 0.0
2.784IleAsp: 2.784 ± 2.386
2.784IleGlu: 2.784 ± 1.647
0.557IlePhe: 0.557 ± 0.5
2.227IleGly: 2.227 ± 0.973
0.557IleHis: 0.557 ± 0.392
1.114IleIle: 1.114 ± 0.543
2.227IleLys: 2.227 ± 1.566
2.784IleLeu: 2.784 ± 1.531
0.557IleMet: 0.557 ± 0.392
3.341IleAsn: 3.341 ± 0.851
2.784IlePro: 2.784 ± 1.962
0.557IleGln: 0.557 ± 0.5
3.341IleArg: 3.341 ± 1.36
3.341IleSer: 3.341 ± 0.83
1.114IleThr: 1.114 ± 0.52
1.67IleVal: 1.67 ± 1.379
2.227IleTrp: 2.227 ± 1.189
3.341IleTyr: 3.341 ± 2.223
0.0IleXaa: 0.0 ± 0.0
Lys
1.67LysAla: 1.67 ± 0.728
0.557LysCys: 0.557 ± 0.788
3.341LysAsp: 3.341 ± 1.357
3.341LysGlu: 3.341 ± 0.928
1.114LysPhe: 1.114 ± 0.52
3.341LysGly: 3.341 ± 1.138
0.0LysHis: 0.0 ± 0.0
0.557LysIle: 0.557 ± 0.729
1.114LysLys: 1.114 ± 0.999
3.341LysLeu: 3.341 ± 1.643
1.67LysMet: 1.67 ± 1.926
3.341LysAsn: 3.341 ± 1.072
0.557LysPro: 0.557 ± 0.729
2.227LysGln: 2.227 ± 1.024
3.898LysArg: 3.898 ± 2.335
3.898LysSer: 3.898 ± 1.95
2.784LysThr: 2.784 ± 0.823
3.898LysVal: 3.898 ± 0.854
0.557LysTrp: 0.557 ± 0.67
1.114LysTyr: 1.114 ± 1.138
0.0LysXaa: 0.0 ± 0.0
Leu
6.125LeuAla: 6.125 ± 1.707
0.557LeuCys: 0.557 ± 0.729
3.898LeuAsp: 3.898 ± 1.786
3.898LeuGlu: 3.898 ± 1.152
6.125LeuPhe: 6.125 ± 2.024
7.238LeuGly: 7.238 ± 2.19
2.227LeuHis: 2.227 ± 1.091
3.341LeuIle: 3.341 ± 1.989
5.011LeuLys: 5.011 ± 1.375
4.454LeuLeu: 4.454 ± 1.364
2.784LeuMet: 2.784 ± 1.312
4.454LeuAsn: 4.454 ± 2.086
6.682LeuPro: 6.682 ± 2.054
2.784LeuGln: 2.784 ± 1.608
7.238LeuArg: 7.238 ± 1.411
9.465LeuSer: 9.465 ± 1.7
5.011LeuThr: 5.011 ± 1.797
5.011LeuVal: 5.011 ± 2.219
0.557LeuTrp: 0.557 ± 0.392
3.898LeuTyr: 3.898 ± 1.536
0.0LeuXaa: 0.0 ± 0.0
Met
2.227MetAla: 2.227 ± 0.924
0.557MetCys: 0.557 ± 0.788
3.341MetAsp: 3.341 ± 1.043
1.67MetGlu: 1.67 ± 1.493
0.557MetPhe: 0.557 ± 0.844
2.784MetGly: 2.784 ± 1.196
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
1.67MetLys: 1.67 ± 1.664
5.011MetLeu: 5.011 ± 2.885
1.67MetMet: 1.67 ± 0.877
0.557MetAsn: 0.557 ± 0.5
0.557MetPro: 0.557 ± 0.5
1.114MetGln: 1.114 ± 1.0
2.784MetArg: 2.784 ± 1.007
5.568MetSer: 5.568 ± 1.139
1.67MetThr: 1.67 ± 1.149
0.0MetVal: 0.0 ± 0.0
0.557MetTrp: 0.557 ± 0.392
0.557MetTyr: 0.557 ± 0.392
0.0MetXaa: 0.0 ± 0.0
Asn
3.341AsnAla: 3.341 ± 1.377
0.0AsnCys: 0.0 ± 0.0
2.227AsnAsp: 2.227 ± 0.914
0.0AsnGlu: 0.0 ± 0.0
1.114AsnPhe: 1.114 ± 0.52
3.898AsnGly: 3.898 ± 2.019
0.557AsnHis: 0.557 ± 0.392
0.557AsnIle: 0.557 ± 0.5
3.341AsnLys: 3.341 ± 1.043
5.011AsnLeu: 5.011 ± 1.741
1.114AsnMet: 1.114 ± 0.52
5.011AsnAsn: 5.011 ± 1.016
2.784AsnPro: 2.784 ± 0.948
2.227AsnGln: 2.227 ± 1.086
5.011AsnArg: 5.011 ± 2.451
3.341AsnSer: 3.341 ± 1.91
2.784AsnThr: 2.784 ± 1.073
3.341AsnVal: 3.341 ± 1.449
0.0AsnTrp: 0.0 ± 0.0
2.227AsnTyr: 2.227 ± 0.793
0.0AsnXaa: 0.0 ± 0.0
Pro
1.114ProAla: 1.114 ± 1.025
0.557ProCys: 0.557 ± 0.569
4.454ProAsp: 4.454 ± 1.645
1.114ProGlu: 1.114 ± 1.238
3.341ProPhe: 3.341 ± 0.977
2.227ProGly: 2.227 ± 1.525
0.557ProHis: 0.557 ± 0.5
2.227ProIle: 2.227 ± 1.477
1.114ProLys: 1.114 ± 1.003
5.568ProLeu: 5.568 ± 1.562
0.557ProMet: 0.557 ± 0.5
0.557ProAsn: 0.557 ± 0.392
0.557ProPro: 0.557 ± 0.729
2.784ProGln: 2.784 ± 0.948
1.67ProArg: 1.67 ± 0.736
6.682ProSer: 6.682 ± 2.45
3.341ProThr: 3.341 ± 1.514
4.454ProVal: 4.454 ± 0.814
0.0ProTrp: 0.0 ± 0.0
2.227ProTyr: 2.227 ± 1.57
0.0ProXaa: 0.0 ± 0.0
Gln
2.227GlnAla: 2.227 ± 1.563
0.557GlnCys: 0.557 ± 0.67
2.227GlnAsp: 2.227 ± 1.086
1.67GlnGlu: 1.67 ± 1.5
3.341GlnPhe: 3.341 ± 1.266
1.67GlnGly: 1.67 ± 1.149
0.0GlnHis: 0.0 ± 0.0
1.67GlnIle: 1.67 ± 0.967
1.114GlnLys: 1.114 ± 1.0
0.557GlnLeu: 0.557 ± 0.5
1.67GlnMet: 1.67 ± 0.488
1.114GlnAsn: 1.114 ± 0.52
0.557GlnPro: 0.557 ± 0.392
3.898GlnGln: 3.898 ± 2.915
5.011GlnArg: 5.011 ± 2.113
3.898GlnSer: 3.898 ± 1.319
3.898GlnThr: 3.898 ± 1.655
2.227GlnVal: 2.227 ± 1.101
0.557GlnTrp: 0.557 ± 0.5
0.557GlnTyr: 0.557 ± 0.5
0.0GlnXaa: 0.0 ± 0.0
Arg
6.125ArgAla: 6.125 ± 1.968
1.114ArgCys: 1.114 ± 0.93
3.898ArgAsp: 3.898 ± 1.353
4.454ArgGlu: 4.454 ± 1.705
2.227ArgPhe: 2.227 ± 0.658
2.784ArgGly: 2.784 ± 1.628
0.557ArgHis: 0.557 ± 0.844
3.898ArgIle: 3.898 ± 2.109
1.67ArgLys: 1.67 ± 1.508
6.125ArgLeu: 6.125 ± 2.195
3.898ArgMet: 3.898 ± 1.329
2.784ArgAsn: 2.784 ± 1.317
2.227ArgPro: 2.227 ± 1.04
2.784ArgGln: 2.784 ± 1.928
3.341ArgArg: 3.341 ± 1.43
6.682ArgSer: 6.682 ± 1.889
0.557ArgThr: 0.557 ± 0.5
2.784ArgVal: 2.784 ± 1.677
0.557ArgTrp: 0.557 ± 0.5
3.341ArgTyr: 3.341 ± 0.719
0.0ArgXaa: 0.0 ± 0.0
Ser
8.909SerAla: 8.909 ± 1.712
1.67SerCys: 1.67 ± 1.017
6.125SerAsp: 6.125 ± 1.045
5.568SerGlu: 5.568 ± 1.955
4.454SerPhe: 4.454 ± 1.32
7.795SerGly: 7.795 ± 3.691
3.341SerHis: 3.341 ± 1.341
6.125SerIle: 6.125 ± 1.665
1.67SerLys: 1.67 ± 0.888
5.568SerLeu: 5.568 ± 1.22
5.011SerMet: 5.011 ± 2.268
3.898SerAsn: 3.898 ± 2.15
5.568SerPro: 5.568 ± 2.59
3.341SerGln: 3.341 ± 1.629
3.898SerArg: 3.898 ± 0.941
16.147SerSer: 16.147 ± 3.672
5.011SerThr: 5.011 ± 0.84
3.898SerVal: 3.898 ± 1.782
2.227SerTrp: 2.227 ± 1.101
5.568SerTyr: 5.568 ± 2.735
0.0SerXaa: 0.0 ± 0.0
Thr
5.568ThrAla: 5.568 ± 2.067
0.557ThrCys: 0.557 ± 0.392
1.114ThrAsp: 1.114 ± 0.712
1.114ThrGlu: 1.114 ± 0.999
4.454ThrPhe: 4.454 ± 1.681
5.568ThrGly: 5.568 ± 1.771
0.557ThrHis: 0.557 ± 0.844
2.784ThrIle: 2.784 ± 1.024
2.227ThrLys: 2.227 ± 1.0
4.454ThrLeu: 4.454 ± 2.046
1.114ThrMet: 1.114 ± 0.727
2.784ThrAsn: 2.784 ± 0.855
2.227ThrPro: 2.227 ± 0.861
3.898ThrGln: 3.898 ± 2.019
2.227ThrArg: 2.227 ± 0.906
5.568ThrSer: 5.568 ± 2.313
2.227ThrThr: 2.227 ± 1.57
3.341ThrVal: 3.341 ± 0.844
0.0ThrTrp: 0.0 ± 0.0
3.341ThrTyr: 3.341 ± 1.007
0.0ThrXaa: 0.0 ± 0.0
Val
4.454ValAla: 4.454 ± 1.401
1.114ValCys: 1.114 ± 1.238
3.898ValAsp: 3.898 ± 0.945
3.898ValGlu: 3.898 ± 2.969
2.784ValPhe: 2.784 ± 1.167
1.67ValGly: 1.67 ± 0.736
0.557ValHis: 0.557 ± 0.729
0.557ValIle: 0.557 ± 0.5
2.784ValLys: 2.784 ± 1.317
7.795ValLeu: 7.795 ± 2.023
1.67ValMet: 1.67 ± 0.963
1.67ValAsn: 1.67 ± 0.488
6.125ValPro: 6.125 ± 1.653
0.557ValGln: 0.557 ± 0.729
2.227ValArg: 2.227 ± 0.765
5.568ValSer: 5.568 ± 1.628
1.67ValThr: 1.67 ± 0.488
3.341ValVal: 3.341 ± 1.154
0.0ValTrp: 0.0 ± 0.0
0.557ValTyr: 0.557 ± 0.392
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.557TrpAsp: 0.557 ± 0.675
0.557TrpGlu: 0.557 ± 0.67
1.114TrpPhe: 1.114 ± 0.811
0.0TrpGly: 0.0 ± 0.0
1.114TrpHis: 1.114 ± 0.76
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
1.67TrpLeu: 1.67 ± 1.095
0.0TrpMet: 0.0 ± 0.0
1.114TrpAsn: 1.114 ± 0.76
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
1.67TrpArg: 1.67 ± 0.805
1.114TrpSer: 1.114 ± 0.785
0.557TrpThr: 0.557 ± 0.392
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.784TyrAla: 2.784 ± 0.694
1.114TyrCys: 1.114 ± 0.944
3.341TyrAsp: 3.341 ± 1.443
1.114TyrGlu: 1.114 ± 0.786
3.898TyrPhe: 3.898 ± 1.147
1.67TyrGly: 1.67 ± 0.797
1.67TyrHis: 1.67 ± 0.869
2.227TyrIle: 2.227 ± 1.145
1.114TyrLys: 1.114 ± 0.633
5.568TyrLeu: 5.568 ± 1.707
1.67TyrMet: 1.67 ± 1.077
2.784TyrAsn: 2.784 ± 1.603
1.114TyrPro: 1.114 ± 0.999
3.341TyrGln: 3.341 ± 0.977
3.898TyrArg: 3.898 ± 0.851
4.454TyrSer: 4.454 ± 1.559
1.114TyrThr: 1.114 ± 0.785
2.227TyrVal: 2.227 ± 1.928
0.557TyrTrp: 0.557 ± 0.392
2.227TyrTyr: 2.227 ± 0.914
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 8 proteins (1797 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski