Amino acid dipepetide frequency for Felis catus (Cat) (Felis silvestris catus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.352AlaAla: 7.352 ± 0.036	1.423AlaCys: 1.423 ± 0.01	2.991AlaAsp: 2.991 ± 0.011	4.831AlaGlu: 4.831 ± 0.025	2.61AlaPhe: 2.61 ± 0.013	5.14AlaGly: 5.14 ± 0.022	1.582AlaHis: 1.582 ± 0.009	2.706AlaIle: 2.706 ± 0.012	3.36AlaLys: 3.36 ± 0.015	7.17AlaLeu: 7.17 ± 0.027	1.449AlaMet: 1.449 ± 0.008	1.996AlaAsn: 1.996 ± 0.009	4.591AlaPro: 4.591 ± 0.024	3.249AlaGln: 3.249 ± 0.016	4.02AlaArg: 4.02 ± 0.019	5.892AlaSer: 5.892 ± 0.021	3.548AlaThr: 3.548 ± 0.015	4.732AlaVal: 4.732 ± 0.014	0.826AlaTrp: 0.826 ± 0.007	1.501AlaTyr: 1.501 ± 0.009	0.0AlaXaa: 0.0 ± 0.0
Cys	1.319CysAla: 1.319 ± 0.011	0.646CysCys: 0.646 ± 0.013	1.008CysAsp: 1.008 ± 0.009	1.265CysGlu: 1.265 ± 0.011	0.84CysPhe: 0.84 ± 0.007	1.723CysGly: 1.723 ± 0.015	0.662CysHis: 0.662 ± 0.006	0.929CysIle: 0.929 ± 0.007	1.109CysLys: 1.109 ± 0.01	2.164CysLeu: 2.164 ± 0.013	0.397CysMet: 0.397 ± 0.004	0.77CysAsn: 0.77 ± 0.007	1.462CysPro: 1.462 ± 0.014	1.057CysGln: 1.057 ± 0.011	1.348CysArg: 1.348 ± 0.01	1.999CysSer: 1.999 ± 0.012	1.081CysThr: 1.081 ± 0.009	1.315CysVal: 1.315 ± 0.011	0.295CysTrp: 0.295 ± 0.004	0.558CysTyr: 0.558 ± 0.005	0.0CysXaa: 0.0 ± 0.0
Asp	2.891AspAla: 2.891 ± 0.012	1.038AspCys: 1.038 ± 0.009	2.583AspAsp: 2.583 ± 0.015	3.394AspGlu: 3.394 ± 0.016	2.1AspPhe: 2.1 ± 0.011	3.355AspGly: 3.355 ± 0.021	1.131AspHis: 1.131 ± 0.008	2.513AspIle: 2.513 ± 0.013	2.468AspLys: 2.468 ± 0.012	4.94AspLeu: 4.94 ± 0.016	1.065AspMet: 1.065 ± 0.007	1.64AspAsn: 1.64 ± 0.01	2.95AspPro: 2.95 ± 0.013	1.8AspGln: 1.8 ± 0.01	2.476AspArg: 2.476 ± 0.011	4.153AspSer: 4.153 ± 0.018	2.437AspThr: 2.437 ± 0.011	3.043AspVal: 3.043 ± 0.012	0.613AspTrp: 0.613 ± 0.006	1.446AspTyr: 1.446 ± 0.008	0.0AspXaa: 0.0 ± 0.0
Glu	5.303GluAla: 5.303 ± 0.024	1.389GluCys: 1.389 ± 0.016	4.344GluAsp: 4.344 ± 0.018	7.827GluGlu: 7.827 ± 0.04	1.985GluPhe: 1.985 ± 0.01	4.292GluGly: 4.292 ± 0.017	1.484GluHis: 1.484 ± 0.009	3.08GluIle: 3.08 ± 0.017	5.261GluLys: 5.261 ± 0.03	6.387GluLeu: 6.387 ± 0.028	1.612GluMet: 1.612 ± 0.009	3.093GluAsn: 3.093 ± 0.015	3.334GluPro: 3.334 ± 0.018	3.125GluGln: 3.125 ± 0.017	4.152GluArg: 4.152 ± 0.021	4.401GluSer: 4.401 ± 0.018	3.376GluThr: 3.376 ± 0.014	4.127GluVal: 4.127 ± 0.015	0.686GluTrp: 0.686 ± 0.005	1.564GluTyr: 1.564 ± 0.012	0.0GluXaa: 0.0 ± 0.0
Phe	1.968PheAla: 1.968 ± 0.012	0.935PheCys: 0.935 ± 0.007	1.638PheAsp: 1.638 ± 0.008	1.956PheGlu: 1.956 ± 0.01	1.615PhePhe: 1.615 ± 0.013	2.17PheGly: 2.17 ± 0.012	1.017PheHis: 1.017 ± 0.007	1.805PheIle: 1.805 ± 0.012	1.733PheLys: 1.733 ± 0.01	4.027PheLeu: 4.027 ± 0.021	0.748PheMet: 0.748 ± 0.006	1.314PheAsn: 1.314 ± 0.009	2.038PhePro: 2.038 ± 0.012	1.759PheGln: 1.759 ± 0.009	1.988PheArg: 1.988 ± 0.013	3.38PheSer: 3.38 ± 0.015	2.001PheThr: 2.001 ± 0.012	2.135PheVal: 2.135 ± 0.011	0.487PheTrp: 0.487 ± 0.005	1.178PheTyr: 1.178 ± 0.008	0.0PheXaa: 0.0 ± 0.0
Gly	4.931GlyAla: 4.931 ± 0.023	1.319GlyCys: 1.319 ± 0.01	3.176GlyAsp: 3.176 ± 0.016	4.191GlyGlu: 4.191 ± 0.024	2.387GlyPhe: 2.387 ± 0.012	5.663GlyGly: 5.663 ± 0.065	1.725GlyHis: 1.725 ± 0.011	2.699GlyIle: 2.699 ± 0.014	3.709GlyLys: 3.709 ± 0.021	5.958GlyLeu: 5.958 ± 0.023	1.266GlyMet: 1.266 ± 0.009	2.329GlyAsn: 2.329 ± 0.012	4.639GlyPro: 4.639 ± 0.038	2.818GlyGln: 2.818 ± 0.015	4.166GlyArg: 4.166 ± 0.018	5.982GlySer: 5.982 ± 0.028	3.623GlyThr: 3.623 ± 0.015	3.595GlyVal: 3.595 ± 0.016	0.836GlyTrp: 0.836 ± 0.006	1.708GlyTyr: 1.708 ± 0.011	0.0GlyXaa: 0.0 ± 0.0
His	1.355HisAla: 1.355 ± 0.008	0.724HisCys: 0.724 ± 0.006	0.871HisAsp: 0.871 ± 0.006	1.29HisGlu: 1.29 ± 0.009	1.068HisPhe: 1.068 ± 0.006	1.586HisGly: 1.586 ± 0.01	0.899HisHis: 0.899 ± 0.01	1.213HisIle: 1.213 ± 0.008	1.222HisLys: 1.222 ± 0.009	2.907HisLeu: 2.907 ± 0.013	0.556HisMet: 0.556 ± 0.005	0.835HisAsn: 0.835 ± 0.006	1.793HisPro: 1.793 ± 0.027	1.318HisGln: 1.318 ± 0.011	1.634HisArg: 1.634 ± 0.01	2.249HisSer: 2.249 ± 0.012	1.488HisThr: 1.488 ± 0.012	1.508HisVal: 1.508 ± 0.009	0.346HisTrp: 0.346 ± 0.004	0.791HisTyr: 0.791 ± 0.006	0.0HisXaa: 0.0 ± 0.0
Ile	2.518IleAla: 2.518 ± 0.011	1.056IleCys: 1.056 ± 0.01	1.949IleAsp: 1.949 ± 0.011	2.523IleGlu: 2.523 ± 0.014	1.836IlePhe: 1.836 ± 0.012	2.16IleGly: 2.16 ± 0.013	1.356IleHis: 1.356 ± 0.021	2.327IleIle: 2.327 ± 0.016	2.544IleLys: 2.544 ± 0.016	4.425IleLeu: 4.425 ± 0.016	0.97IleMet: 0.97 ± 0.007	1.769IleAsn: 1.769 ± 0.01	2.563IlePro: 2.563 ± 0.013	2.241IleGln: 2.241 ± 0.012	2.351IleArg: 2.351 ± 0.011	3.605IleSer: 3.605 ± 0.015	2.505IleThr: 2.505 ± 0.016	2.438IleVal: 2.438 ± 0.014	0.502IleTrp: 0.502 ± 0.005	1.373IleTyr: 1.373 ± 0.01	0.0IleXaa: 0.0 ± 0.0
Lys	3.912LysAla: 3.912 ± 0.019	1.082LysCys: 1.082 ± 0.009	3.093LysAsp: 3.093 ± 0.016	5.009LysGlu: 5.009 ± 0.028	1.687LysPhe: 1.687 ± 0.009	3.207LysGly: 3.207 ± 0.02	1.375LysHis: 1.375 ± 0.01	2.697LysIle: 2.697 ± 0.015	4.585LysLys: 4.585 ± 0.036	5.029LysLeu: 5.029 ± 0.019	1.393LysMet: 1.393 ± 0.008	2.333LysAsn: 2.333 ± 0.013	3.077LysPro: 3.077 ± 0.018	2.55LysGln: 2.55 ± 0.013	3.249LysArg: 3.249 ± 0.014	3.858LysSer: 3.858 ± 0.016	3.028LysThr: 3.028 ± 0.015	3.359LysVal: 3.359 ± 0.018	0.594LysTrp: 0.594 ± 0.007	1.501LysTyr: 1.501 ± 0.01	0.0LysXaa: 0.0 ± 0.0
Leu	6.784LeuAla: 6.784 ± 0.023	2.187LeuCys: 2.187 ± 0.013	4.654LeuAsp: 4.654 ± 0.016	7.118LeuGlu: 7.118 ± 0.027	3.353LeuPhe: 3.353 ± 0.016	5.908LeuGly: 5.908 ± 0.02	2.696LeuHis: 2.696 ± 0.014	3.762LeuIle: 3.762 ± 0.016	5.654LeuLys: 5.654 ± 0.027	10.672LeuLeu: 10.672 ± 0.035	1.956LeuMet: 1.956 ± 0.01	3.449LeuAsn: 3.449 ± 0.013	6.189LeuPro: 6.189 ± 0.023	5.669LeuGln: 5.669 ± 0.025	6.077LeuArg: 6.077 ± 0.023	8.046LeuSer: 8.046 ± 0.025	5.034LeuThr: 5.034 ± 0.016	5.449LeuVal: 5.449 ± 0.02	1.137LeuTrp: 1.137 ± 0.007	2.505LeuTyr: 2.505 ± 0.011	0.0LeuXaa: 0.0 ± 0.0
Met	1.871MetAla: 1.871 ± 0.01	0.394MetCys: 0.394 ± 0.004	1.21MetAsp: 1.21 ± 0.007	1.783MetGlu: 1.783 ± 0.01	0.711MetPhe: 0.711 ± 0.006	1.258MetGly: 1.258 ± 0.008	0.446MetHis: 0.446 ± 0.005	0.812MetIle: 0.812 ± 0.007	1.388MetLys: 1.388 ± 0.008	1.911MetLeu: 1.911 ± 0.009	0.547MetMet: 0.547 ± 0.005	0.869MetAsn: 0.869 ± 0.006	1.055MetPro: 1.055 ± 0.009	0.888MetGln: 0.888 ± 0.007	1.029MetArg: 1.029 ± 0.006	1.513MetSer: 1.513 ± 0.008	1.088MetThr: 1.088 ± 0.007	1.348MetVal: 1.348 ± 0.008	0.234MetTrp: 0.234 ± 0.004	0.573MetTyr: 0.573 ± 0.006	0.0MetXaa: 0.0 ± 0.0
Asn	2.002AsnAla: 2.002 ± 0.01	0.827AsnCys: 0.827 ± 0.007	1.476AsnAsp: 1.476 ± 0.01	2.167AsnGlu: 2.167 ± 0.012	1.439AsnPhe: 1.439 ± 0.01	2.453AsnGly: 2.453 ± 0.016	0.934AsnHis: 0.934 ± 0.007	2.061AsnIle: 2.061 ± 0.01	2.139AsnLys: 2.139 ± 0.012	3.612AsnLeu: 3.612 ± 0.014	0.878AsnMet: 0.878 ± 0.007	1.475AsnAsn: 1.475 ± 0.01	2.173AsnPro: 2.173 ± 0.011	1.615AsnGln: 1.615 ± 0.01	1.815AsnArg: 1.815 ± 0.008	3.069AsnSer: 3.069 ± 0.015	1.923AsnThr: 1.923 ± 0.01	2.147AsnVal: 2.147 ± 0.01	0.437AsnTrp: 0.437 ± 0.004	1.079AsnTyr: 1.079 ± 0.009	0.0AsnXaa: 0.0 ± 0.0
Pro	5.355ProAla: 5.355 ± 0.025	1.191ProCys: 1.191 ± 0.011	2.826ProAsp: 2.826 ± 0.013	4.564ProGlu: 4.564 ± 0.02	1.953ProPhe: 1.953 ± 0.013	5.733ProGly: 5.733 ± 0.053	1.504ProHis: 1.504 ± 0.009	1.847ProIle: 1.847 ± 0.013	2.788ProLys: 2.788 ± 0.015	5.416ProLeu: 5.416 ± 0.019	1.023ProMet: 1.023 ± 0.008	1.789ProAsn: 1.789 ± 0.009	7.23ProPro: 7.23 ± 0.12	2.907ProGln: 2.907 ± 0.017	3.747ProArg: 3.747 ± 0.016	6.008ProSer: 6.008 ± 0.04	3.16ProThr: 3.16 ± 0.015	3.916ProVal: 3.916 ± 0.018	0.716ProTrp: 0.716 ± 0.005	1.465ProTyr: 1.465 ± 0.01	0.0ProXaa: 0.0 ± 0.0
Gln	3.522GlnAla: 3.522 ± 0.016	0.932GlnCys: 0.932 ± 0.009	2.3GlnAsp: 2.3 ± 0.01	3.854GlnGlu: 3.854 ± 0.02	1.329GlnPhe: 1.329 ± 0.008	2.866GlnGly: 2.866 ± 0.015	1.277GlnHis: 1.277 ± 0.01	1.954GlnIle: 1.954 ± 0.01	2.881GlnLys: 2.881 ± 0.014	4.67GlnLeu: 4.67 ± 0.02	1.1GlnMet: 1.1 ± 0.007	1.814GlnAsn: 1.814 ± 0.011	2.871GlnPro: 2.871 ± 0.019	2.984GlnGln: 2.984 ± 0.025	3.017GlnArg: 3.017 ± 0.017	3.14GlnSer: 3.14 ± 0.014	2.298GlnThr: 2.298 ± 0.011	2.791GlnVal: 2.791 ± 0.012	0.534GlnTrp: 0.534 ± 0.005	1.129GlnTyr: 1.129 ± 0.008	0.0GlnXaa: 0.0 ± 0.0
Arg	4.185ArgAla: 4.185 ± 0.017	1.273ArgCys: 1.273 ± 0.011	2.786ArgAsp: 2.786 ± 0.012	4.159ArgGlu: 4.159 ± 0.021	1.839ArgPhe: 1.839 ± 0.01	3.975ArgGly: 3.975 ± 0.022	1.572ArgHis: 1.572 ± 0.009	2.385ArgIle: 2.385 ± 0.011	3.689ArgLys: 3.689 ± 0.018	5.565ArgLeu: 5.565 ± 0.018	1.169ArgMet: 1.169 ± 0.008	2.103ArgAsn: 2.103 ± 0.01	3.62ArgPro: 3.62 ± 0.018	2.696ArgGln: 2.696 ± 0.015	4.696ArgArg: 4.696 ± 0.022	4.455ArgSer: 4.455 ± 0.024	2.921ArgThr: 2.921 ± 0.012	3.244ArgVal: 3.244 ± 0.015	0.729ArgTrp: 0.729 ± 0.006	1.452ArgTyr: 1.452 ± 0.008	0.0ArgXaa: 0.0 ± 0.0
Ser	5.448SerAla: 5.448 ± 0.019	1.857SerCys: 1.857 ± 0.012	3.888SerAsp: 3.888 ± 0.016	5.175SerGlu: 5.175 ± 0.022	3.025SerPhe: 3.025 ± 0.013	5.808SerGly: 5.808 ± 0.026	2.084SerHis: 2.084 ± 0.011	3.184SerIle: 3.184 ± 0.026	3.976SerLys: 3.976 ± 0.017	8.26SerLeu: 8.26 ± 0.027	1.537SerMet: 1.537 ± 0.008	2.611SerAsn: 2.611 ± 0.014	6.335SerPro: 6.335 ± 0.03	3.871SerGln: 3.871 ± 0.018	4.726SerArg: 4.726 ± 0.023	9.311SerSer: 9.311 ± 0.046	4.4SerThr: 4.4 ± 0.022	4.948SerVal: 4.948 ± 0.018	1.067SerTrp: 1.067 ± 0.007	2.041SerTyr: 2.041 ± 0.011	0.0SerXaa: 0.0 ± 0.0
Thr	3.782ThrAla: 3.782 ± 0.014	1.304ThrCys: 1.304 ± 0.013	2.448ThrAsp: 2.448 ± 0.012	3.496ThrGlu: 3.496 ± 0.015	2.091ThrPhe: 2.091 ± 0.01	3.553ThrGly: 3.553 ± 0.018	1.322ThrHis: 1.322 ± 0.012	2.314ThrIle: 2.314 ± 0.013	2.593ThrLys: 2.593 ± 0.014	5.22ThrLeu: 5.22 ± 0.017	1.083ThrMet: 1.083 ± 0.007	1.693ThrAsn: 1.693 ± 0.01	3.621ThrPro: 3.621 ± 0.021	2.257ThrGln: 2.257 ± 0.011	2.545ThrArg: 2.545 ± 0.011	4.552ThrSer: 4.552 ± 0.021	2.868ThrThr: 2.868 ± 0.018	3.857ThrVal: 3.857 ± 0.019	0.692ThrTrp: 0.692 ± 0.007	1.399ThrTyr: 1.399 ± 0.009	0.0ThrXaa: 0.0 ± 0.0
Val	4.278ValAla: 4.278 ± 0.014	1.46ValCys: 1.46 ± 0.011	2.887ValAsp: 2.887 ± 0.013	3.757ValGlu: 3.757 ± 0.017	2.38ValPhe: 2.38 ± 0.012	3.45ValGly: 3.45 ± 0.014	1.555ValHis: 1.555 ± 0.009	2.833ValIle: 2.833 ± 0.016	3.309ValLys: 3.309 ± 0.017	6.161ValLeu: 6.161 ± 0.023	1.291ValMet: 1.291 ± 0.007	2.248ValAsn: 2.248 ± 0.012	3.751ValPro: 3.751 ± 0.014	2.697ValGln: 2.697 ± 0.012	3.14ValArg: 3.14 ± 0.012	4.919ValSer: 4.919 ± 0.018	3.775ValThr: 3.775 ± 0.02	3.916ValVal: 3.916 ± 0.017	0.72ValTrp: 0.72 ± 0.006	1.596ValTyr: 1.596 ± 0.009	0.0ValXaa: 0.0 ± 0.0
Trp	0.81TrpAla: 0.81 ± 0.007	0.248TrpCys: 0.248 ± 0.003	0.64TrpAsp: 0.64 ± 0.005	0.802TrpGlu: 0.802 ± 0.006	0.438TrpPhe: 0.438 ± 0.006	0.776TrpGly: 0.776 ± 0.008	0.301TrpHis: 0.301 ± 0.004	0.529TrpIle: 0.529 ± 0.005	0.791TrpLys: 0.791 ± 0.006	1.212TrpLeu: 1.212 ± 0.009	0.312TrpMet: 0.312 ± 0.004	0.525TrpAsn: 0.525 ± 0.005	0.558TrpPro: 0.558 ± 0.005	0.531TrpGln: 0.531 ± 0.004	0.76TrpArg: 0.76 ± 0.006	0.869TrpSer: 0.869 ± 0.007	0.684TrpThr: 0.684 ± 0.007	0.689TrpVal: 0.689 ± 0.006	0.199TrpTrp: 0.199 ± 0.003	0.325TrpTyr: 0.325 ± 0.004	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.385TyrAla: 1.385 ± 0.008	0.66TyrCys: 0.66 ± 0.007	1.267TyrAsp: 1.267 ± 0.009	1.661TyrGlu: 1.661 ± 0.01	1.204TyrPhe: 1.204 ± 0.009	1.644TyrGly: 1.644 ± 0.01	0.734TyrHis: 0.734 ± 0.006	1.36TyrIle: 1.36 ± 0.011	1.42TyrLys: 1.42 ± 0.009	2.591TyrLeu: 2.591 ± 0.012	0.579TyrMet: 0.579 ± 0.005	1.066TyrAsn: 1.066 ± 0.008	1.285TyrPro: 1.285 ± 0.008	1.23TyrGln: 1.23 ± 0.008	1.579TyrArg: 1.579 ± 0.009	2.152TyrSer: 2.152 ± 0.01	1.449TyrThr: 1.449 ± 0.01	1.569TyrVal: 1.569 ± 0.01	0.35TyrTrp: 0.35 ± 0.004	0.916TyrTyr: 0.916 ± 0.008	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.008XaaXaa: 0.008 ± 0.003

Statistics based on 40225 proteins (24765678 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---