Amino acid dipepetide frequency for Termitomyces sp. J132

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.332AlaAla: 7.332 ± 0.059	1.021AlaCys: 1.021 ± 0.014	3.815AlaAsp: 3.815 ± 0.027	4.517AlaGlu: 4.517 ± 0.037	3.182AlaPhe: 3.182 ± 0.031	4.863AlaGly: 4.863 ± 0.037	1.963AlaHis: 1.963 ± 0.023	4.215AlaIle: 4.215 ± 0.031	3.84AlaLys: 3.84 ± 0.035	7.94AlaLeu: 7.94 ± 0.049	1.736AlaMet: 1.736 ± 0.018	2.851AlaAsn: 2.851 ± 0.03	4.497AlaPro: 4.497 ± 0.04	3.16AlaGln: 3.16 ± 0.027	4.643AlaArg: 4.643 ± 0.038	7.01AlaSer: 7.01 ± 0.047	4.897AlaThr: 4.897 ± 0.037	4.936AlaVal: 4.936 ± 0.038	1.069AlaTrp: 1.069 ± 0.016	2.11AlaTyr: 2.11 ± 0.025	0.002AlaXaa: 0.002 ± 0.001
Cys	0.888CysAla: 0.888 ± 0.013	0.233CysCys: 0.233 ± 0.008	0.616CysAsp: 0.616 ± 0.012	0.568CysGlu: 0.568 ± 0.012	0.541CysPhe: 0.541 ± 0.011	0.85CysGly: 0.85 ± 0.014	0.382CysHis: 0.382 ± 0.01	0.765CysIle: 0.765 ± 0.014	0.579CysLys: 0.579 ± 0.013	1.363CysLeu: 1.363 ± 0.02	0.274CysMet: 0.274 ± 0.008	0.481CysAsn: 0.481 ± 0.011	0.773CysPro: 0.773 ± 0.014	0.485CysGln: 0.485 ± 0.011	0.699CysArg: 0.699 ± 0.013	0.993CysSer: 0.993 ± 0.016	0.784CysThr: 0.784 ± 0.016	0.804CysVal: 0.804 ± 0.014	0.216CysTrp: 0.216 ± 0.007	0.367CysTyr: 0.367 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	4.325AspAla: 4.325 ± 0.035	0.626AspCys: 0.626 ± 0.012	4.017AspAsp: 4.017 ± 0.045	4.067AspGlu: 4.067 ± 0.035	2.201AspPhe: 2.201 ± 0.025	3.61AspGly: 3.61 ± 0.035	1.355AspHis: 1.355 ± 0.018	3.302AspIle: 3.302 ± 0.025	2.296AspLys: 2.296 ± 0.025	5.216AspLeu: 5.216 ± 0.033	1.177AspMet: 1.177 ± 0.015	2.019AspAsn: 2.019 ± 0.021	3.372AspPro: 3.372 ± 0.029	1.724AspGln: 1.724 ± 0.022	2.705AspArg: 2.705 ± 0.027	4.088AspSer: 4.088 ± 0.033	3.011AspThr: 3.011 ± 0.026	3.983AspVal: 3.983 ± 0.028	0.863AspTrp: 0.863 ± 0.012	1.432AspTyr: 1.432 ± 0.018	0.0AspXaa: 0.0 ± 0.0
Glu	4.964GluAla: 4.964 ± 0.043	0.683GluCys: 0.683 ± 0.012	3.941GluAsp: 3.941 ± 0.039	5.423GluGlu: 5.423 ± 0.063	1.987GluPhe: 1.987 ± 0.026	3.519GluGly: 3.519 ± 0.032	1.469GluHis: 1.469 ± 0.021	3.151GluIle: 3.151 ± 0.028	3.348GluLys: 3.348 ± 0.036	5.473GluLeu: 5.473 ± 0.038	1.339GluMet: 1.339 ± 0.018	2.182GluAsn: 2.182 ± 0.022	2.528GluPro: 2.528 ± 0.03	2.243GluGln: 2.243 ± 0.025	3.898GluArg: 3.898 ± 0.038	3.868GluSer: 3.868 ± 0.036	3.175GluThr: 3.175 ± 0.027	3.815GluVal: 3.815 ± 0.032	0.947GluTrp: 0.947 ± 0.016	1.577GluTyr: 1.577 ± 0.015	0.001GluXaa: 0.001 ± 0.0
Phe	3.022PheAla: 3.022 ± 0.028	0.56PheCys: 0.56 ± 0.011	2.378PheAsp: 2.378 ± 0.023	2.147PheGlu: 2.147 ± 0.025	1.711PhePhe: 1.711 ± 0.021	2.637PheGly: 2.637 ± 0.032	1.028PheHis: 1.028 ± 0.017	1.992PheIle: 1.992 ± 0.024	1.646PheLys: 1.646 ± 0.021	3.713PheLeu: 3.713 ± 0.034	0.752PheMet: 0.752 ± 0.012	1.531PheAsn: 1.531 ± 0.018	2.115PhePro: 2.115 ± 0.021	1.37PheGln: 1.37 ± 0.019	1.913PheArg: 1.913 ± 0.023	3.334PheSer: 3.334 ± 0.027	2.232PheThr: 2.232 ± 0.025	2.549PheVal: 2.549 ± 0.025	0.568PheTrp: 0.568 ± 0.011	1.131PheTyr: 1.131 ± 0.016	0.001PheXaa: 0.001 ± 0.0
Gly	4.447GlyAla: 4.447 ± 0.037	0.827GlyCys: 0.827 ± 0.014	3.205GlyAsp: 3.205 ± 0.029	3.302GlyGlu: 3.302 ± 0.028	2.487GlyPhe: 2.487 ± 0.03	4.918GlyGly: 4.918 ± 0.06	1.685GlyHis: 1.685 ± 0.022	3.33GlyIle: 3.33 ± 0.033	3.49GlyLys: 3.49 ± 0.033	5.643GlyLeu: 5.643 ± 0.038	1.409GlyMet: 1.409 ± 0.021	2.334GlyAsn: 2.334 ± 0.034	3.123GlyPro: 3.123 ± 0.027	2.191GlyGln: 2.191 ± 0.027	3.713GlyArg: 3.713 ± 0.032	5.179GlySer: 5.179 ± 0.041	3.774GlyThr: 3.774 ± 0.034	4.175GlyVal: 4.175 ± 0.039	1.079GlyTrp: 1.079 ± 0.015	1.829GlyTyr: 1.829 ± 0.021	0.001GlyXaa: 0.001 ± 0.0
His	1.956HisAla: 1.956 ± 0.021	0.404HisCys: 0.404 ± 0.01	1.315HisAsp: 1.315 ± 0.018	1.305HisGlu: 1.305 ± 0.017	1.022HisPhe: 1.022 ± 0.017	1.593HisGly: 1.593 ± 0.02	0.941HisHis: 0.941 ± 0.018	1.526HisIle: 1.526 ± 0.02	1.053HisLys: 1.053 ± 0.016	2.651HisLeu: 2.651 ± 0.028	0.495HisMet: 0.495 ± 0.01	0.969HisAsn: 0.969 ± 0.013	1.955HisPro: 1.955 ± 0.021	0.982HisGln: 0.982 ± 0.018	1.565HisArg: 1.565 ± 0.02	2.146HisSer: 2.146 ± 0.027	1.535HisThr: 1.535 ± 0.016	1.676HisVal: 1.676 ± 0.02	0.394HisTrp: 0.394 ± 0.01	0.758HisTyr: 0.758 ± 0.014	0.0HisXaa: 0.0 ± 0.0
Ile	4.154IleAla: 4.154 ± 0.036	0.825IleCys: 0.825 ± 0.013	3.058IleAsp: 3.058 ± 0.028	3.006IleGlu: 3.006 ± 0.032	2.156IlePhe: 2.156 ± 0.026	3.1IleGly: 3.1 ± 0.03	1.441IleHis: 1.441 ± 0.019	2.851IleIle: 2.851 ± 0.03	2.397IleLys: 2.397 ± 0.023	5.158IleLeu: 5.158 ± 0.038	1.007IleMet: 1.007 ± 0.016	1.934IleAsn: 1.934 ± 0.021	3.571IlePro: 3.571 ± 0.029	2.069IleGln: 2.069 ± 0.02	2.89IleArg: 2.89 ± 0.026	4.354IleSer: 4.354 ± 0.032	3.099IleThr: 3.099 ± 0.027	3.566IleVal: 3.566 ± 0.03	0.744IleTrp: 0.744 ± 0.013	1.463IleTyr: 1.463 ± 0.018	0.0IleXaa: 0.0 ± 0.0
Lys	4.137LysAla: 4.137 ± 0.038	0.547LysCys: 0.547 ± 0.013	2.673LysAsp: 2.673 ± 0.025	3.467LysGlu: 3.467 ± 0.033	1.547LysPhe: 1.547 ± 0.02	2.888LysGly: 2.888 ± 0.029	1.179LysHis: 1.179 ± 0.017	2.38LysIle: 2.38 ± 0.024	3.169LysLys: 3.169 ± 0.039	4.181LysLeu: 4.181 ± 0.035	0.989LysMet: 0.989 ± 0.015	1.774LysAsn: 1.774 ± 0.019	2.531LysPro: 2.531 ± 0.023	1.806LysGln: 1.806 ± 0.023	3.343LysArg: 3.343 ± 0.032	3.394LysSer: 3.394 ± 0.033	2.838LysThr: 2.838 ± 0.028	2.961LysVal: 2.961 ± 0.026	0.692LysTrp: 0.692 ± 0.013	1.334LysTyr: 1.334 ± 0.018	0.0LysXaa: 0.0 ± 0.0
Leu	7.847LeuAla: 7.847 ± 0.056	1.311LeuCys: 1.311 ± 0.015	5.377LeuAsp: 5.377 ± 0.037	5.7LeuGlu: 5.7 ± 0.046	3.577LeuPhe: 3.577 ± 0.032	5.712LeuGly: 5.712 ± 0.04	2.631LeuHis: 2.631 ± 0.027	4.403LeuIle: 4.403 ± 0.039	4.425LeuLys: 4.425 ± 0.034	9.117LeuLeu: 9.117 ± 0.064	1.81LeuMet: 1.81 ± 0.02	3.515LeuAsn: 3.515 ± 0.03	6.202LeuPro: 6.202 ± 0.044	4.081LeuGln: 4.081 ± 0.037	5.835LeuArg: 5.835 ± 0.043	8.209LeuSer: 8.209 ± 0.049	5.498LeuThr: 5.498 ± 0.039	5.931LeuVal: 5.931 ± 0.043	1.229LeuTrp: 1.229 ± 0.017	2.447LeuTyr: 2.447 ± 0.026	0.001LeuXaa: 0.001 ± 0.0
Met	1.746MetAla: 1.746 ± 0.019	0.231MetCys: 0.231 ± 0.008	1.235MetAsp: 1.235 ± 0.016	1.278MetGlu: 1.278 ± 0.019	0.765MetPhe: 0.765 ± 0.012	1.249MetGly: 1.249 ± 0.018	0.502MetHis: 0.502 ± 0.009	1.108MetIle: 1.108 ± 0.015	1.009MetLys: 1.009 ± 0.017	1.841MetLeu: 1.841 ± 0.018	0.51MetMet: 0.51 ± 0.011	0.787MetAsn: 0.787 ± 0.013	1.219MetPro: 1.219 ± 0.017	0.833MetGln: 0.833 ± 0.015	1.181MetArg: 1.181 ± 0.016	1.803MetSer: 1.803 ± 0.021	1.325MetThr: 1.325 ± 0.015	1.196MetVal: 1.196 ± 0.016	0.276MetTrp: 0.276 ± 0.009	0.52MetTyr: 0.52 ± 0.009	0.0MetXaa: 0.0 ± 0.0
Asn	3.013AsnAla: 3.013 ± 0.025	0.456AsnCys: 0.456 ± 0.01	2.072AsnAsp: 2.072 ± 0.023	2.021AsnGlu: 2.021 ± 0.023	1.433AsnPhe: 1.433 ± 0.021	2.631AsnGly: 2.631 ± 0.037	0.913AsnHis: 0.913 ± 0.016	2.258AsnIle: 2.258 ± 0.024	1.617AsnLys: 1.617 ± 0.019	3.596AsnLeu: 3.596 ± 0.031	0.847AsnMet: 0.847 ± 0.013	1.616AsnAsn: 1.616 ± 0.022	2.577AsnPro: 2.577 ± 0.03	1.27AsnGln: 1.27 ± 0.017	1.781AsnArg: 1.781 ± 0.019	2.982AsnSer: 2.982 ± 0.036	2.33AsnThr: 2.33 ± 0.025	2.551AsnVal: 2.551 ± 0.025	0.502AsnTrp: 0.502 ± 0.01	0.992AsnTyr: 0.992 ± 0.017	0.0AsnXaa: 0.0 ± 0.0
Pro	4.878ProAla: 4.878 ± 0.041	0.571ProCys: 0.571 ± 0.011	3.174ProAsp: 3.174 ± 0.026	3.487ProGlu: 3.487 ± 0.029	2.311ProPhe: 2.311 ± 0.025	3.482ProGly: 3.482 ± 0.035	1.658ProHis: 1.658 ± 0.02	2.946ProIle: 2.946 ± 0.031	2.579ProLys: 2.579 ± 0.024	5.476ProLeu: 5.476 ± 0.038	1.042ProMet: 1.042 ± 0.017	2.368ProAsn: 2.368 ± 0.025	5.938ProPro: 5.938 ± 0.073	2.325ProGln: 2.325 ± 0.03	3.34ProArg: 3.34 ± 0.033	6.799ProSer: 6.799 ± 0.057	4.433ProThr: 4.433 ± 0.042	3.896ProVal: 3.896 ± 0.032	0.675ProTrp: 0.675 ± 0.012	1.607ProTyr: 1.607 ± 0.019	0.002ProXaa: 0.002 ± 0.001
Gln	3.108GlnAla: 3.108 ± 0.028	0.524GlnCys: 0.524 ± 0.013	1.932GlnAsp: 1.932 ± 0.022	2.371GlnGlu: 2.371 ± 0.028	1.279GlnPhe: 1.279 ± 0.018	2.175GlnGly: 2.175 ± 0.019	1.038GlnHis: 1.038 ± 0.016	1.973GlnIle: 1.973 ± 0.023	1.772GlnLys: 1.772 ± 0.02	3.54GlnLeu: 3.54 ± 0.031	0.831GlnMet: 0.831 ± 0.012	1.456GlnAsn: 1.456 ± 0.019	2.367GlnPro: 2.367 ± 0.027	2.051GlnGln: 2.051 ± 0.037	2.46GlnArg: 2.46 ± 0.028	3.016GlnSer: 3.016 ± 0.032	2.329GlnThr: 2.329 ± 0.025	2.363GlnVal: 2.363 ± 0.022	0.547GlnTrp: 0.547 ± 0.01	1.117GlnTyr: 1.117 ± 0.017	0.0GlnXaa: 0.0 ± 0.0
Arg	4.465ArgAla: 4.465 ± 0.036	0.698ArgCys: 0.698 ± 0.012	3.041ArgAsp: 3.041 ± 0.03	3.781ArgGlu: 3.781 ± 0.039	2.106ArgPhe: 2.106 ± 0.023	3.364ArgGly: 3.364 ± 0.031	1.53ArgHis: 1.53 ± 0.02	3.087ArgIle: 3.087 ± 0.025	3.26ArgLys: 3.26 ± 0.031	5.57ArgLeu: 5.57 ± 0.042	1.262ArgMet: 1.262 ± 0.018	2.138ArgAsn: 2.138 ± 0.024	3.375ArgPro: 3.375 ± 0.034	2.259ArgGln: 2.259 ± 0.029	4.621ArgArg: 4.621 ± 0.047	4.63ArgSer: 4.63 ± 0.042	3.374ArgThr: 3.374 ± 0.03	3.508ArgVal: 3.508 ± 0.03	0.905ArgTrp: 0.905 ± 0.015	1.582ArgTyr: 1.582 ± 0.019	0.001ArgXaa: 0.001 ± 0.0
Ser	6.494SerAla: 6.494 ± 0.047	0.934SerCys: 0.934 ± 0.016	4.389SerAsp: 4.389 ± 0.037	3.975SerGlu: 3.975 ± 0.035	3.225SerPhe: 3.225 ± 0.028	5.358SerGly: 5.358 ± 0.047	2.215SerHis: 2.215 ± 0.024	4.418SerIle: 4.418 ± 0.032	3.685SerLys: 3.685 ± 0.033	8.024SerLeu: 8.024 ± 0.055	1.7SerMet: 1.7 ± 0.022	3.152SerAsn: 3.152 ± 0.031	5.992SerPro: 5.992 ± 0.063	3.252SerGln: 3.252 ± 0.029	4.818SerArg: 4.818 ± 0.038	9.661SerSer: 9.661 ± 0.097	6.053SerThr: 6.053 ± 0.052	5.174SerVal: 5.174 ± 0.035	1.055SerTrp: 1.055 ± 0.015	2.061SerTyr: 2.061 ± 0.023	0.001SerXaa: 0.001 ± 0.001
Thr	4.613ThrAla: 4.613 ± 0.035	0.765ThrCys: 0.765 ± 0.013	2.807ThrAsp: 2.807 ± 0.026	2.881ThrGlu: 2.881 ± 0.026	2.516ThrPhe: 2.516 ± 0.028	3.723ThrGly: 3.723 ± 0.035	1.532ThrHis: 1.532 ± 0.019	3.492ThrIle: 3.492 ± 0.031	2.619ThrLys: 2.619 ± 0.026	5.982ThrLeu: 5.982 ± 0.044	1.259ThrMet: 1.259 ± 0.017	2.224ThrAsn: 2.224 ± 0.019	4.665ThrPro: 4.665 ± 0.046	2.206ThrGln: 2.206 ± 0.024	3.268ThrArg: 3.268 ± 0.026	6.063ThrSer: 6.063 ± 0.046	4.364ThrThr: 4.364 ± 0.045	3.822ThrVal: 3.822 ± 0.032	0.844ThrTrp: 0.844 ± 0.016	1.682ThrTyr: 1.682 ± 0.019	0.0ThrXaa: 0.0 ± 0.0
Val	5.086ValAla: 5.086 ± 0.035	0.875ValCys: 0.875 ± 0.017	3.793ValAsp: 3.793 ± 0.03	3.953ValGlu: 3.953 ± 0.035	2.549ValPhe: 2.549 ± 0.025	3.9ValGly: 3.9 ± 0.033	1.648ValHis: 1.648 ± 0.021	3.347ValIle: 3.347 ± 0.032	3.048ValLys: 3.048 ± 0.032	6.234ValLeu: 6.234 ± 0.038	1.303ValMet: 1.303 ± 0.017	2.322ValAsn: 2.322 ± 0.024	4.023ValPro: 4.023 ± 0.031	2.413ValGln: 2.413 ± 0.02	3.472ValArg: 3.472 ± 0.031	4.923ValSer: 4.923 ± 0.039	3.736ValThr: 3.736 ± 0.033	4.578ValVal: 4.578 ± 0.035	0.965ValTrp: 0.965 ± 0.018	1.847ValTyr: 1.847 ± 0.021	0.001ValXaa: 0.001 ± 0.0
Trp	1.059TrpAla: 1.059 ± 0.016	0.198TrpCys: 0.198 ± 0.006	0.926TrpAsp: 0.926 ± 0.016	0.86TrpGlu: 0.86 ± 0.014	0.584TrpPhe: 0.584 ± 0.01	0.839TrpGly: 0.839 ± 0.015	0.341TrpHis: 0.341 ± 0.009	0.797TrpIle: 0.797 ± 0.013	0.828TrpLys: 0.828 ± 0.014	1.287TrpLeu: 1.287 ± 0.018	0.317TrpMet: 0.317 ± 0.008	0.636TrpAsn: 0.636 ± 0.013	0.57TrpPro: 0.57 ± 0.012	0.51TrpGln: 0.51 ± 0.011	0.905TrpArg: 0.905 ± 0.015	1.147TrpSer: 1.147 ± 0.017	0.895TrpThr: 0.895 ± 0.016	0.864TrpVal: 0.864 ± 0.015	0.258TrpTrp: 0.258 ± 0.008	0.383TrpTyr: 0.383 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.065TyrAla: 2.065 ± 0.024	0.376TyrCys: 0.376 ± 0.009	1.621TyrAsp: 1.621 ± 0.021	1.417TyrGlu: 1.417 ± 0.017	1.156TyrPhe: 1.156 ± 0.016	1.73TyrGly: 1.73 ± 0.021	0.79TyrHis: 0.79 ± 0.013	1.501TyrIle: 1.501 ± 0.019	1.17TyrLys: 1.17 ± 0.018	2.851TyrLeu: 2.851 ± 0.024	0.553TyrMet: 0.553 ± 0.01	1.169TyrAsn: 1.169 ± 0.018	1.589TyrPro: 1.589 ± 0.025	1.017TyrGln: 1.017 ± 0.017	1.507TyrArg: 1.507 ± 0.02	2.035TyrSer: 2.035 ± 0.024	1.647TyrThr: 1.647 ± 0.019	1.667TyrVal: 1.667 ± 0.02	0.379TyrTrp: 0.379 ± 0.01	0.876TyrTyr: 0.876 ± 0.016	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.001XaaAla: 0.001 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.002XaaGlu: 0.002 ± 0.001	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.001XaaLys: 0.001 ± 0.0	0.002XaaLeu: 0.002 ± 0.001	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.002XaaPro: 0.002 ± 0.001	0.0XaaGln: 0.0 ± 0.0	0.001XaaArg: 0.001 ± 0.0	0.001XaaSer: 0.001 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.001XaaVal: 0.001 ± 0.001	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.403XaaXaa: 0.403 ± 0.102

Statistics based on 11124 proteins (4621127 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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