Human immunodeficiency virus type 1 group N (isolate YBF106) (HIV-1)

Taxonomy: Viruses; Riboviria; Pararnavirae; Artverviricota; Revtraviricetes; Ortervirales; Retroviridae; Orthoretrovirinae; Lentivirus; Human immunodeficiency virus 1; HIV-1 group N

Average proteome isoelectric point is 7.8

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 10 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>sp|Q9IDV2|ENV_HV1YB Envelope glycoprotein gp160 OS=Human immunodeficiency virus type 1 group N (isolate YBF106) OX=388819 GN=env PE=3 SV=1
MGKIWSKSSLVGWPEIRERIRRQTPEPAVGVGAVSQDLANRGAITTSNTKDNNQTVAWLEAQEEQEVGFPVRPQVPLRPMTYKAAFDLSFFLKEKGGLEGLVWSRKRQEILDLWVYHTQGFFPDWQNYTPGPGVRYPLCFGWCFKLVPLSEEAVEEANEGDNNALLHPICQHGVDDDHKQVLVWRFDSSLARRHVAKELHPDFYKNC

Molecular weight: 23.72 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>sp|Q9IDV5|TAT_HV1YB Protein Tat OS=Human immunodeficiency virus type 1 group N (isolate YBF106) OX=388819 GN=tat PE=3 SV=1
MM1 pKa = 7.78AGRR4 pKa = 11.84SGVNDD9 pKa = 3.6EE10 pKa = 5.17DD11 pKa = 3.86LLKK14 pKa = 10.56AVKK17 pKa = 9.79IIKK20 pKa = 9.6ILYY23 pKa = 8.83QSNPYY28 pKa = 9.08PDD30 pKa = 4.07SSQGTRR36 pKa = 11.84QARR39 pKa = 11.84RR40 pKa = 11.84NRR42 pKa = 11.84RR43 pKa = 11.84RR44 pKa = 11.84RR45 pKa = 11.84WRR47 pKa = 11.84ARR49 pKa = 11.84QRR51 pKa = 11.84QIRR54 pKa = 11.84AISEE58 pKa = 4.55RR59 pKa = 11.84ILGAYY64 pKa = 9.96LGGPQEE70 pKa = 4.54PVDD73 pKa = 5.08LPLPPLGRR81 pKa = 11.84LTLDD85 pKa = 3.24HH86 pKa = 7.12KK87 pKa = 10.85EE88 pKa = 4.16DD89 pKa = 3.72SGDD92 pKa = 3.7PGTEE96 pKa = 4.12SQQGTATTEE105 pKa = 3.7

Molecular weight: 11.78 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

9

1

10

3643

72

1449

364.3

40.85

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.725 ± 0.559

2.141 ± 0.465

3.953 ± 0.313

6.78 ± 0.58

2.388 ± 0.236

7.631 ± 0.201

2.251 ± 0.418

6.506 ± 0.916

7.11 ± 0.986

8.153 ± 0.678

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.059 ± 0.253

4.584 ± 0.644

5.792 ± 0.778

5.792 ± 0.267

5.71 ± 0.761

4.721 ± 0.509

5.902 ± 0.594

5.764 ± 0.48

2.69 ± 0.277

2.718 ± 0.246
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski