Hubei picorna-like virus 74

Taxonomy: Viruses; Riboviria; unclassified Riboviria; unclassified RNA viruses ShiM-2016

Average proteome isoelectric point is 5.12

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 3 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

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* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    

Protein with the lowest isoelectric point:
>tr|A0A1L3KLY4|A0A1L3KLY4_9VIRU Uncharacterized protein OS=Hubei picorna-like virus 74 OX=1923158 PE=4 SV=1
MM1 pKa = 7.67AGFAAAGAAALGIGASFASPFINQSLDD28 pKa = 3.23YY29 pKa = 11.27QNFLKK34 pKa = 9.6QQNYY38 pKa = 6.76MQSQYY43 pKa = 10.8EE44 pKa = 4.51KK45 pKa = 10.73YY46 pKa = 10.16GLPYY50 pKa = 10.8LPGFDD55 pKa = 4.66FKK57 pKa = 11.12NAPPSSFVNHH67 pKa = 6.42SSGTNIEE74 pKa = 4.11ISHH77 pKa = 6.08MPFMIGGAFGTMFGTNDD94 pKa = 3.13WGNQGSSGDD103 pKa = 3.92GVNSSRR109 pKa = 11.84DD110 pKa = 3.33SGSAYY115 pKa = 9.76PGLGYY120 pKa = 10.72GNNYY124 pKa = 9.51SAVPPPPSYY133 pKa = 11.15SSGGQRR139 pKa = 11.84DD140 pKa = 4.01LVQGKK145 pKa = 8.69PGLSGGIQYY154 pKa = 11.12SLNTLNTPDD163 pKa = 3.43EE164 pKa = 4.39SEE166 pKa = 4.14YY167 pKa = 11.18AGPINTRR174 pKa = 11.84SVYY177 pKa = 9.84TSALVRR183 pKa = 11.84PPALNFSHH191 pKa = 6.71EE192 pKa = 4.28VADD195 pKa = 4.11LSGASGVHH203 pKa = 4.9RR204 pKa = 11.84TTLNTQYY211 pKa = 10.46FSSTRR216 pKa = 11.84PVPTTFSVQADD227 pKa = 3.7VHH229 pKa = 6.14TPIQLNSGVKK239 pKa = 9.72PDD241 pKa = 4.14FGQNLGLPSRR251 pKa = 11.84PFSSVSRR258 pKa = 11.84VTRR261 pKa = 11.84GSSVATDD268 pKa = 3.34SDD270 pKa = 4.64EE271 pKa = 4.51ILPDD275 pKa = 4.47PDD277 pKa = 3.83TTDD280 pKa = 3.37SANLSSDD287 pKa = 3.94FQSSTADD294 pKa = 3.17SEE296 pKa = 4.66ANNNIVSEE304 pKa = 4.26DD305 pKa = 3.72APIGAVDD312 pKa = 4.57DD313 pKa = 4.35SADD316 pKa = 3.37IDD318 pKa = 3.85AEE320 pKa = 4.51SILGSSAGIPLL331 pKa = 3.79

Molecular weight:
34.54 kDa
Isoelectric point according different methods:






Protein with the highest isoelectric point:
>tr|A0A1L3KLX7|A0A1L3KLX7_9VIRU Uncharacterized protein OS=Hubei picorna-like virus 74 OX=1923158 PE=4 SV=1
MM1 pKa = 7.27SCSKK5 pKa = 10.42RR6 pKa = 11.84ALIDD10 pKa = 3.45CDD12 pKa = 3.93VVKK15 pKa = 10.91DD16 pKa = 3.98CIVPNVEE23 pKa = 4.43SRR25 pKa = 11.84EE26 pKa = 3.92TDD28 pKa = 2.97LSSFYY33 pKa = 9.56QLCFIEE39 pKa = 4.64PNKK42 pKa = 10.4QSTDD46 pKa = 3.37VEE48 pKa = 4.73DD49 pKa = 3.86NSNLEE54 pKa = 3.99EE55 pKa = 4.31DD56 pKa = 4.26LKK58 pKa = 11.42SVSQCYY64 pKa = 10.0NYY66 pKa = 10.6SDD68 pKa = 4.13SEE70 pKa = 4.29EE71 pKa = 5.1GDD73 pKa = 3.65VLSSVLSLNSAVFSVLSRR91 pKa = 11.84AKK93 pKa = 10.38LLNLIDD99 pKa = 3.56QLSNVFVADD108 pKa = 3.83SFVSALAPLARR119 pKa = 11.84ICEE122 pKa = 4.35LYY124 pKa = 10.65GYY126 pKa = 9.97LWSDD130 pKa = 3.46VNGQMGVLEE139 pKa = 4.38ILWNVLVWMKK149 pKa = 11.04DD150 pKa = 3.34LIVPLFKK157 pKa = 10.61GSKK160 pKa = 9.47LVPDD164 pKa = 4.29DD165 pKa = 3.86VKK167 pKa = 11.43SRR169 pKa = 11.84LPDD172 pKa = 3.54TEE174 pKa = 4.03PVKK177 pKa = 10.61QAFVKK182 pKa = 10.67LSEE185 pKa = 4.19DD186 pKa = 3.08RR187 pKa = 11.84KK188 pKa = 10.81GKK190 pKa = 10.08IKK192 pKa = 10.95SFFEE196 pKa = 4.42NIGCHH201 pKa = 4.91EE202 pKa = 4.23LAGRR206 pKa = 11.84VPYY209 pKa = 10.21LVPVLATVVTGALAFVAFRR228 pKa = 11.84FGPAMLQQKK237 pKa = 9.14EE238 pKa = 4.26MNFVKK243 pKa = 10.49SVTAMGMLARR253 pKa = 11.84SSHH256 pKa = 5.5FLRR259 pKa = 11.84AEE261 pKa = 3.92FASIWKK267 pKa = 9.73VATDD271 pKa = 3.87CFAEE275 pKa = 4.18IFGLAWVEE283 pKa = 3.93DD284 pKa = 3.65ADD286 pKa = 4.62IEE288 pKa = 4.58VKK290 pKa = 10.51KK291 pKa = 10.83YY292 pKa = 10.72ISDD295 pKa = 3.52LHH297 pKa = 7.68SLYY300 pKa = 10.89KK301 pKa = 10.43EE302 pKa = 3.65FRR304 pKa = 11.84QYY306 pKa = 10.31QNRR309 pKa = 11.84ILSDD313 pKa = 3.69PYY315 pKa = 11.42VVFGDD320 pKa = 3.79QEE322 pKa = 4.11FLPRR326 pKa = 11.84LEE328 pKa = 4.55LQLKK332 pKa = 10.24RR333 pKa = 11.84LDD335 pKa = 3.88DD336 pKa = 4.22FYY338 pKa = 11.88LRR340 pKa = 11.84LASAKK345 pKa = 10.56KK346 pKa = 10.5NMVNAKK352 pKa = 9.9SALDD356 pKa = 3.59SLRR359 pKa = 11.84EE360 pKa = 3.79MAKK363 pKa = 10.16EE364 pKa = 3.77SRR366 pKa = 11.84LLVDD370 pKa = 4.23NIKK373 pKa = 9.34RR374 pKa = 11.84TCTEE378 pKa = 3.77KK379 pKa = 10.51IEE381 pKa = 4.18PVVIWLSGAAGIGKK395 pKa = 9.18SRR397 pKa = 11.84AVSKK401 pKa = 10.58IVEE404 pKa = 4.35EE405 pKa = 4.08LGKK408 pKa = 10.49LHH410 pKa = 7.13GEE412 pKa = 4.11VLHH415 pKa = 6.25TYY417 pKa = 10.07VRR419 pKa = 11.84GTADD423 pKa = 3.78QYY425 pKa = 9.4WSGYY429 pKa = 8.9SGQPVVIYY437 pKa = 10.72DD438 pKa = 3.53DD439 pKa = 4.15FGNSKK444 pKa = 10.34EE445 pKa = 4.08KK446 pKa = 10.61TEE448 pKa = 4.02FTEE451 pKa = 4.11LVSIKK456 pKa = 9.4TCQAFLLNCAAVEE469 pKa = 4.16EE470 pKa = 4.44KK471 pKa = 11.11GKK473 pKa = 10.58LFTSKK478 pKa = 10.94YY479 pKa = 10.81VIICANMLDD488 pKa = 4.14VVNTAQIPNVEE499 pKa = 4.14VLNRR503 pKa = 11.84RR504 pKa = 11.84RR505 pKa = 11.84DD506 pKa = 3.54FLFVVEE512 pKa = 5.05NPEE515 pKa = 3.78LTNYY519 pKa = 8.91VQVNGRR525 pKa = 11.84EE526 pKa = 3.99PTADD530 pKa = 3.48CDD532 pKa = 2.95IWKK535 pKa = 10.23DD536 pKa = 3.85DD537 pKa = 4.1FSHH540 pKa = 5.42LTIRR544 pKa = 11.84RR545 pKa = 11.84RR546 pKa = 11.84AALPRR551 pKa = 11.84DD552 pKa = 3.43RR553 pKa = 11.84DD554 pKa = 3.6AVRR557 pKa = 11.84DD558 pKa = 3.73NSEE561 pKa = 3.48WDD563 pKa = 3.48VFRR566 pKa = 11.84IAQEE570 pKa = 3.92SYY572 pKa = 9.35VRR574 pKa = 11.84FRR576 pKa = 11.84TAEE579 pKa = 3.75QKK581 pKa = 10.35FYY583 pKa = 11.01HH584 pKa = 6.41YY585 pKa = 10.3LTDD588 pKa = 3.58LQTRR592 pKa = 11.84RR593 pKa = 11.84QRR595 pKa = 11.84LQDD598 pKa = 3.42AVEE601 pKa = 4.86DD602 pKa = 4.1KK603 pKa = 11.13DD604 pKa = 4.13GLPSAPVCAVRR615 pKa = 11.84GGGEE619 pKa = 4.14SSVSDD624 pKa = 3.72SEE626 pKa = 4.16VLEE629 pKa = 4.09RR630 pKa = 11.84FGFLFDD636 pKa = 3.36TDD638 pKa = 3.38EE639 pKa = 4.54PEE641 pKa = 3.82RR642 pKa = 11.84QFFHH646 pKa = 6.68QFEE649 pKa = 4.53RR650 pKa = 11.84QIHH653 pKa = 4.7MPILFVGEE661 pKa = 4.13AGTGKK666 pKa = 8.2TFTMHH671 pKa = 7.28AIRR674 pKa = 11.84RR675 pKa = 11.84RR676 pKa = 11.84FEE678 pKa = 3.74QEE680 pKa = 3.49KK681 pKa = 10.43LKK683 pKa = 11.03VRR685 pKa = 11.84MFSGTQFQTFFDD697 pKa = 4.07GGGKK701 pKa = 6.24VTKK704 pKa = 10.3YY705 pKa = 10.84DD706 pKa = 3.57VILIEE711 pKa = 4.93DD712 pKa = 4.03FTVTAEE718 pKa = 3.8AMNAFRR724 pKa = 11.84TFVNEE729 pKa = 3.97AEE731 pKa = 4.74DD732 pKa = 3.96GFFGKK737 pKa = 10.34KK738 pKa = 9.05IVVATGNLSLVHH750 pKa = 6.31DD751 pKa = 4.71HH752 pKa = 6.75AAGRR756 pKa = 11.84GVDD759 pKa = 3.13WLAAFEE765 pKa = 4.16RR766 pKa = 11.84RR767 pKa = 11.84VRR769 pKa = 11.84IYY771 pKa = 10.13QFSFKK776 pKa = 10.45RR777 pKa = 11.84RR778 pKa = 11.84WLFKK782 pKa = 8.65YY783 pKa = 9.11TPADD787 pKa = 3.39VVANPEE793 pKa = 4.09NYY795 pKa = 10.39DD796 pKa = 3.3VMVRR800 pKa = 11.84ISASTLTTQEE810 pKa = 4.12RR811 pKa = 11.84SDD813 pKa = 3.61LFQRR817 pKa = 11.84DD818 pKa = 3.71LIDD821 pKa = 3.81FVVQATPRR829 pKa = 11.84VALYY833 pKa = 8.09QTFEE837 pKa = 4.22SLPKK841 pKa = 9.79IGEE844 pKa = 4.09VEE846 pKa = 3.97ATFEE850 pKa = 4.39VVLKK854 pKa = 7.52VTPSDD859 pKa = 3.33FLKK862 pKa = 10.44WMKK865 pKa = 10.24SKK867 pKa = 10.74KK868 pKa = 10.08GVYY871 pKa = 8.8TPAGVAAAIAEE882 pKa = 4.35VHH884 pKa = 6.41SMISVPFSKK893 pKa = 10.08MVFFGRR899 pKa = 11.84FLHH902 pKa = 6.98SMAAKK907 pKa = 10.62GIGLSLMSGWRR918 pKa = 11.84TEE920 pKa = 4.3RR921 pKa = 11.84NMLTLRR927 pKa = 11.84DD928 pKa = 3.57ILVNVANLNIEE939 pKa = 4.24FPTSEE944 pKa = 4.18VVRR947 pKa = 11.84FRR949 pKa = 11.84YY950 pKa = 9.89ADD952 pKa = 3.5EE953 pKa = 5.76AYY955 pKa = 10.45LLCASDD961 pKa = 3.81EE962 pKa = 4.13GRR964 pKa = 11.84LCILEE969 pKa = 4.23EE970 pKa = 4.52CPDD973 pKa = 3.44GFVRR977 pKa = 11.84QTGSFVGGVDD987 pKa = 3.31YY988 pKa = 10.65TKK990 pKa = 10.77DD991 pKa = 3.22EE992 pKa = 4.45KK993 pKa = 11.41EE994 pKa = 3.76FMQRR998 pKa = 11.84VSHH1001 pKa = 6.24VIQRR1005 pKa = 11.84QRR1007 pKa = 11.84VAMKK1011 pKa = 9.97EE1012 pKa = 4.03KK1013 pKa = 10.14QDD1015 pKa = 3.44KK1016 pKa = 10.14CGKK1019 pKa = 9.6AFEE1022 pKa = 4.27RR1023 pKa = 11.84MIVSGGLKK1031 pKa = 8.94TLPAWARR1038 pKa = 11.84ALFEE1042 pKa = 4.31AVNVLLLYY1050 pKa = 8.69GTAVVTLQDD1059 pKa = 2.96SYY1061 pKa = 11.74VRR1063 pKa = 11.84YY1064 pKa = 9.57RR1065 pKa = 11.84QLQDD1069 pKa = 3.43LKK1071 pKa = 10.93EE1072 pKa = 4.23KK1073 pKa = 10.98KK1074 pKa = 10.01NLLDD1078 pKa = 3.78EE1079 pKa = 4.91FCTPEE1084 pKa = 5.13LEE1086 pKa = 4.29GQKK1089 pKa = 9.77PSKK1092 pKa = 11.11VEE1094 pKa = 3.54ITEE1097 pKa = 4.21TFVLKK1102 pKa = 10.56DD1103 pKa = 3.95PKK1105 pKa = 11.25VKK1107 pKa = 10.36GQPEE1111 pKa = 4.09KK1112 pKa = 10.73VSTVVHH1118 pKa = 5.84VNGKK1122 pKa = 7.95SYY1124 pKa = 11.12RR1125 pKa = 11.84EE1126 pKa = 3.86AGMASWGSDD1135 pKa = 2.62SSLSSNVSLPPMMRR1149 pKa = 11.84APKK1152 pKa = 8.4PTARR1156 pKa = 11.84RR1157 pKa = 11.84SAGGGGGTSVTLQDD1171 pKa = 3.46TPTYY1175 pKa = 8.4ATKK1178 pKa = 10.4SYY1180 pKa = 10.93SYY1182 pKa = 10.18MRR1184 pKa = 11.84NLEE1187 pKa = 3.92VAKK1190 pKa = 10.35PGLRR1194 pKa = 11.84LRR1196 pKa = 11.84EE1197 pKa = 3.89NSVAPVTTVASSAQPIMAARR1217 pKa = 11.84YY1218 pKa = 9.18ADD1220 pKa = 3.63VVQPSQYY1227 pKa = 11.26DD1228 pKa = 3.52LDD1230 pKa = 5.78RR1231 pKa = 11.84IANMQRR1237 pKa = 11.84VYY1239 pKa = 10.85EE1240 pKa = 4.19KK1241 pKa = 10.94NGLQRR1246 pKa = 11.84TVLMPSPTLQKK1257 pKa = 10.58KK1258 pKa = 10.4LEE1260 pKa = 4.46TIVEE1264 pKa = 4.2SEE1266 pKa = 4.28EE1267 pKa = 3.9ISNEE1271 pKa = 3.71VLDD1274 pKa = 4.29QLNCEE1279 pKa = 4.09EE1280 pKa = 5.15FEE1282 pKa = 4.43VQRR1285 pKa = 11.84EE1286 pKa = 4.35SQSDD1290 pKa = 3.81PQAHH1294 pKa = 7.09DD1295 pKa = 3.56LAEE1298 pKa = 4.14LCIVNSVSIVYY1309 pKa = 10.35ADD1311 pKa = 3.74SKK1313 pKa = 8.15EE1314 pKa = 4.02HH1315 pKa = 6.02CVYY1318 pKa = 11.28GLMIAEE1324 pKa = 4.23DD1325 pKa = 3.55VGVTVLHH1332 pKa = 6.67CASACLNVEE1341 pKa = 4.05ILSTPGVYY1349 pKa = 10.34YY1350 pKa = 11.11DD1351 pKa = 4.04MVLLSKK1357 pKa = 10.9DD1358 pKa = 3.06RR1359 pKa = 11.84TRR1361 pKa = 11.84DD1362 pKa = 3.31LMIFRR1367 pKa = 11.84VQSCPAKK1374 pKa = 10.1FRR1376 pKa = 11.84NITNHH1381 pKa = 5.92LRR1383 pKa = 11.84SEE1385 pKa = 4.69LYY1387 pKa = 7.56TTEE1390 pKa = 4.14IDD1392 pKa = 3.31GHH1394 pKa = 6.5DD1395 pKa = 3.93AMLVTPSSRR1404 pKa = 11.84NRR1406 pKa = 11.84VGWKK1410 pKa = 8.33RR1411 pKa = 11.84WAVVRR1416 pKa = 11.84ACVSRR1421 pKa = 11.84KK1422 pKa = 9.08YY1423 pKa = 10.54AGSDD1427 pKa = 3.42VVEE1430 pKa = 4.43HH1431 pKa = 6.24EE1432 pKa = 4.05RR1433 pKa = 11.84TYY1435 pKa = 11.44VGMLAGYY1442 pKa = 9.81KK1443 pKa = 9.67IVTGVGTASGDD1454 pKa = 3.86CGSSLILNSARR1465 pKa = 11.84LPFKK1469 pKa = 10.93LIGIHH1474 pKa = 6.91KK1475 pKa = 10.11AATDD1479 pKa = 3.66KK1480 pKa = 11.19VGYY1483 pKa = 9.26AAEE1486 pKa = 4.14IFRR1489 pKa = 11.84EE1490 pKa = 4.18DD1491 pKa = 3.2FQEE1494 pKa = 3.93FVPIKK1499 pKa = 10.0EE1500 pKa = 4.43PNRR1503 pKa = 11.84QRR1505 pKa = 11.84ALKK1508 pKa = 9.89RR1509 pKa = 11.84DD1510 pKa = 3.87EE1511 pKa = 4.79IEE1513 pKa = 4.73LFQEE1517 pKa = 4.07PMPVGRR1523 pKa = 11.84TTQIVGRR1530 pKa = 11.84AVFRR1534 pKa = 11.84NHH1536 pKa = 6.14QSVKK1540 pKa = 7.84TQFYY1544 pKa = 9.49RR1545 pKa = 11.84CPLACPFLDD1554 pKa = 5.35DD1555 pKa = 3.89EE1556 pKa = 4.94FEE1558 pKa = 4.2PVILSHH1564 pKa = 6.89QDD1566 pKa = 3.14FRR1568 pKa = 11.84CRR1570 pKa = 11.84DD1571 pKa = 3.06TDD1573 pKa = 4.49FYY1575 pKa = 11.15PEE1577 pKa = 4.0DD1578 pKa = 5.12AFLKK1582 pKa = 9.89WDD1584 pKa = 3.91GPTGFEE1590 pKa = 4.03IDD1592 pKa = 4.32CAPFSADD1599 pKa = 2.4VRR1601 pKa = 11.84AQIFEE1606 pKa = 4.28MVSDD1610 pKa = 4.14QICDD1614 pKa = 2.88KK1615 pKa = 10.68WIFEE1619 pKa = 4.53CEE1621 pKa = 3.81RR1622 pKa = 11.84LHH1624 pKa = 7.5RR1625 pKa = 11.84PLFKK1629 pKa = 10.05LTKK1632 pKa = 9.12TEE1634 pKa = 4.63AINRR1638 pKa = 11.84PSQCIGLSNSLNRR1651 pKa = 11.84ASSPGYY1657 pKa = 8.95PFRR1660 pKa = 11.84HH1661 pKa = 6.01FGARR1665 pKa = 11.84RR1666 pKa = 11.84GKK1668 pKa = 10.62ADD1670 pKa = 3.5FLEE1673 pKa = 4.53FDD1675 pKa = 4.04EE1676 pKa = 5.72GQQIWMLAKK1685 pKa = 10.38NEE1687 pKa = 4.1HH1688 pKa = 5.83GRR1690 pKa = 11.84LLNHH1694 pKa = 6.98SIDD1697 pKa = 3.9LFVDD1701 pKa = 4.13EE1702 pKa = 4.96ARR1704 pKa = 11.84RR1705 pKa = 11.84GNVPPIVYY1713 pKa = 9.48VANLKK1718 pKa = 10.94DD1719 pKa = 3.45EE1720 pKa = 4.28TRR1722 pKa = 11.84KK1723 pKa = 9.91KK1724 pKa = 10.77DD1725 pKa = 3.95RR1726 pKa = 11.84IYY1728 pKa = 10.26EE1729 pKa = 4.06QPKK1732 pKa = 8.41TRR1734 pKa = 11.84GFAAAPVHH1742 pKa = 5.44YY1743 pKa = 10.12VIAGRR1748 pKa = 11.84MYY1750 pKa = 10.67NYY1752 pKa = 10.95AAMALCAEE1760 pKa = 4.36ARR1762 pKa = 11.84AQLGHH1767 pKa = 6.13VLGMDD1772 pKa = 3.69PNSLEE1777 pKa = 4.05WHH1779 pKa = 6.13SMTLRR1784 pKa = 11.84LVSKK1788 pKa = 9.59SNCIINGDD1796 pKa = 3.87YY1797 pKa = 10.99KK1798 pKa = 11.32DD1799 pKa = 3.75FDD1801 pKa = 3.77SGHH1804 pKa = 5.6FRR1806 pKa = 11.84EE1807 pKa = 5.05ALALPTRR1814 pKa = 11.84IRR1816 pKa = 11.84CEE1818 pKa = 3.58LYY1820 pKa = 10.39RR1821 pKa = 11.84RR1822 pKa = 11.84LDD1824 pKa = 3.8PGWRR1828 pKa = 11.84PEE1830 pKa = 3.8DD1831 pKa = 3.48TIIRR1835 pKa = 11.84EE1836 pKa = 4.32NIDD1839 pKa = 3.1RR1840 pKa = 11.84ASQYY1844 pKa = 11.28GLLLRR1849 pKa = 11.84GHH1851 pKa = 7.55LLFQHH1856 pKa = 6.34SKK1858 pKa = 11.24GIFSGQFDD1866 pKa = 3.97TTFNNCVLNQLYY1878 pKa = 9.56IVYY1881 pKa = 9.77AWFVTMFEE1889 pKa = 4.54KK1890 pKa = 10.72KK1891 pKa = 10.3RR1892 pKa = 11.84FDD1894 pKa = 3.71LMSLGGFDD1902 pKa = 4.25KK1903 pKa = 10.24MCHH1906 pKa = 6.39LEE1908 pKa = 4.04VCGDD1912 pKa = 4.03DD1913 pKa = 4.0FNLSISDD1920 pKa = 3.93LDD1922 pKa = 4.14LFGLQDD1928 pKa = 3.36IVRR1931 pKa = 11.84VLSQHH1936 pKa = 5.94FGIVVTSASAKK1947 pKa = 10.63DD1948 pKa = 3.59STQSVLPYY1956 pKa = 10.2EE1957 pKa = 5.22DD1958 pKa = 3.62IYY1960 pKa = 11.49EE1961 pKa = 4.01VDD1963 pKa = 3.8FLKK1966 pKa = 10.6RR1967 pKa = 11.84QYY1969 pKa = 11.1VCIGGRR1975 pKa = 11.84WCGRR1979 pKa = 11.84VKK1981 pKa = 10.46MSVFDD1986 pKa = 5.97KK1987 pKa = 10.56MLNWCVGPKK1996 pKa = 9.87RR1997 pKa = 11.84CLTPEE2002 pKa = 3.71NLYY2005 pKa = 11.18DD2006 pKa = 4.11EE2007 pKa = 5.2FFDD2010 pKa = 3.85MTNMCALMDD2019 pKa = 3.77VALIEE2024 pKa = 4.05AVFWGRR2030 pKa = 11.84EE2031 pKa = 3.97LYY2033 pKa = 9.97EE2034 pKa = 4.01KK2035 pKa = 10.67LVAHH2039 pKa = 6.64FRR2041 pKa = 11.84SFLCQPGIDD2050 pKa = 3.7IQKK2053 pKa = 10.22DD2054 pKa = 3.68LPSYY2058 pKa = 12.02DD2059 pKa = 3.35MMCILFEE2066 pKa = 4.39LVPSDD2071 pKa = 3.13MRR2073 pKa = 11.84VFGNVCRR2080 pKa = 11.84NQIAVTDD2087 pKa = 3.91KK2088 pKa = 11.35QMATVKK2094 pKa = 10.09NAKK2097 pKa = 9.47PSAAGVEE2104 pKa = 4.13PQNINVPDD2112 pKa = 4.01VPVSPPDD2119 pKa = 3.26QMSPYY2124 pKa = 10.86APTATNATQQASQGIGCVPLSVPHH2148 pKa = 6.7IVGKK2152 pKa = 8.3YY2153 pKa = 6.67VWNEE2157 pKa = 4.0TISITTNDD2165 pKa = 3.63EE2166 pKa = 4.01PGKK2169 pKa = 8.86VLWWRR2174 pKa = 11.84ALHH2177 pKa = 6.72PSTNPYY2183 pKa = 10.75ADD2185 pKa = 3.54WLTKK2189 pKa = 10.21PFNAWAGGMLFRR2201 pKa = 11.84ATICANFLCAGKK2213 pKa = 10.33VVLVHH2218 pKa = 6.53WMPNQNPTLEE2228 pKa = 4.22RR2229 pKa = 11.84TLEE2232 pKa = 4.0EE2233 pKa = 4.73VTCQPHH2239 pKa = 5.75MMCDD2243 pKa = 3.91LKK2245 pKa = 11.64NMEE2248 pKa = 4.3TTEE2251 pKa = 4.61LLVEE2255 pKa = 4.79DD2256 pKa = 4.44EE2257 pKa = 5.81NPTKK2261 pKa = 8.91WHH2263 pKa = 6.81YY2264 pKa = 7.72YY2265 pKa = 9.84QPMPQMNTDD2274 pKa = 3.45PDD2276 pKa = 4.28GNITPSEE2283 pKa = 4.2WFSSLGVGGYY2293 pKa = 9.64IAMYY2297 pKa = 10.0VYY2299 pKa = 11.0GRR2301 pKa = 11.84FNMGEE2306 pKa = 3.99GSLNSLDD2313 pKa = 4.35IIVEE2317 pKa = 4.29SAVAPSFTVNYY2328 pKa = 8.72LKK2330 pKa = 10.41SVRR2333 pKa = 11.84SSDD2336 pKa = 3.55TPKK2339 pKa = 10.64PGVAQEE2345 pKa = 3.69AWQTLKK2351 pKa = 10.92DD2352 pKa = 3.75ASIPFCPTSPHH2363 pKa = 6.2PNKK2366 pKa = 10.32IIVTPQPVFGFDD2378 pKa = 2.82TVAQMTCGGTFWDD2391 pKa = 4.27TNWWKK2396 pKa = 11.28GDD2398 pKa = 3.52FEE2400 pKa = 4.45LAADD2404 pKa = 4.2RR2405 pKa = 11.84ATNVGQVNLIPTGTTQSGPTFTATYY2430 pKa = 8.29DD2431 pKa = 3.4TFVNEE2436 pKa = 4.1FVPNKK2441 pKa = 9.45ISRR2444 pKa = 11.84VLYY2447 pKa = 9.5CIRR2450 pKa = 11.84GGKK2453 pKa = 9.65FYY2455 pKa = 10.86DD2456 pKa = 3.55WTVGSYY2462 pKa = 9.87FNWNIEE2468 pKa = 3.89TRR2470 pKa = 11.84KK2471 pKa = 10.26YY2472 pKa = 10.39EE2473 pKa = 4.18GAKK2476 pKa = 7.83MTYY2479 pKa = 8.37TMEE2482 pKa = 4.99DD2483 pKa = 2.95AGLPASDD2490 pKa = 4.68NRR2492 pKa = 11.84PHH2494 pKa = 7.73LIGTYY2499 pKa = 10.95SMDD2502 pKa = 5.39DD2503 pKa = 3.37EE2504 pKa = 4.99FEE2506 pKa = 4.28YY2507 pKa = 10.01PAYY2510 pKa = 10.0PEE2512 pKa = 4.07DD2513 pKa = 3.55TKK2515 pKa = 11.41KK2516 pKa = 10.48FVPGVPEE2523 pKa = 3.85SLIMFGRR2530 pKa = 11.84YY2531 pKa = 8.19DD2532 pKa = 3.31QNYY2535 pKa = 7.71PFPSASFQTQEE2546 pKa = 3.98MVKK2549 pKa = 10.49AFYY2552 pKa = 11.11SKK2554 pKa = 9.34TSKK2557 pKa = 10.09IASQITPTTAGLFMIYY2573 pKa = 8.74DD2574 pKa = 4.24TKK2576 pKa = 11.35NRR2578 pKa = 11.84LPVRR2582 pKa = 11.84QCKK2585 pKa = 10.01LYY2587 pKa = 10.6YY2588 pKa = 10.29EE2589 pKa = 4.81GFLTVMASDD2598 pKa = 4.42KK2599 pKa = 11.17YY2600 pKa = 11.18EE2601 pKa = 4.42IMDD2604 pKa = 4.18SDD2606 pKa = 4.43YY2607 pKa = 10.82EE2608 pKa = 4.18LQFMSIVDD2616 pKa = 3.81RR2617 pKa = 11.84NYY2619 pKa = 10.63VIKK2622 pKa = 10.67DD2623 pKa = 3.33KK2624 pKa = 11.51QNLIEE2629 pKa = 4.22NSEE2632 pKa = 4.03FAKK2635 pKa = 10.78NQDD2638 pKa = 4.03RR2639 pKa = 11.84IRR2641 pKa = 11.84KK2642 pKa = 7.46ATAFLEE2648 pKa = 4.37RR2649 pKa = 11.84TDD2651 pKa = 3.61LTKK2654 pKa = 10.74LEE2656 pKa = 4.18RR2657 pKa = 11.84LAGIVTQHH2665 pKa = 6.21WGSLTRR2671 pKa = 11.84RR2672 pKa = 3.64

Molecular weight:
302.8 kDa
Isoelectric point according different methods:






Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

3

0

3

3450

331

2672

1150.0

129.72

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.928 ± 0.431

1.913 ± 0.503

6.232 ± 0.116

5.739 ± 1.132

5.565 ± 0.311

5.971 ± 1.117

1.681 ± 0.068

4.725 ± 0.293

4.87 ± 1.038

8.319 ± 0.487

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.551 ± 0.43

4.377 ± 0.697

4.986 ± 0.765

4.058 ± 0.213

5.623 ± 0.786

7.42 ± 1.907

5.536 ± 0.105

8.087 ± 0.772

1.362 ± 0.324

4.058 ± 0.974

Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski