Human hepatitis A virus genotype IB (isolate HM175) (HHAV) (Human hepatitis A virus (isolate Human/Australia/HM175/1976))
Taxonomy: Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes; Picornavirales; Picornaviridae; Hepatovirus; Hepatovirus A; Human hepatitis A virus
Average proteome isoelectric point is 5.74
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Virtual 2D-PAGE plot for 1 proteins (isoelectric point calculated using IPC2_protein)
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Summary statistics related to proteome-wise predictions
Protein with the lowest isoelectric point:
>sp|P08617|POLG_HAVHM Genome polyprotein OS=Human hepatitis A virus genotype IB (isolate HM175) OX=12098 PE=1 SV=1
MM1 pKa = 7.18NMSRR5 pKa = 11.84QGIFQTVGSGLDD17 pKa = 4.01HH18 pKa = 6.92ILSLADD24 pKa = 3.29IEE26 pKa = 4.36EE27 pKa = 4.16EE28 pKa = 4.58QMIQSVDD35 pKa = 3.17RR36 pKa = 11.84TAVTGASYY44 pKa = 7.83FTSVDD49 pKa = 3.17QSSVHH54 pKa = 4.42TAEE57 pKa = 4.41VGSHH61 pKa = 4.06QVEE64 pKa = 4.31PLRR67 pKa = 11.84TSVDD71 pKa = 3.18KK72 pKa = 11.07PGSKK76 pKa = 8.56KK77 pKa = 8.1TQGEE81 pKa = 4.49KK82 pKa = 10.68FFLIHH87 pKa = 6.17SADD90 pKa = 3.33WLTTHH95 pKa = 7.47ALFHH99 pKa = 6.33EE100 pKa = 4.75VAKK103 pKa = 10.89LDD105 pKa = 4.08VVKK108 pKa = 10.69LLYY111 pKa = 10.5NEE113 pKa = 3.96QFAVQGLLRR122 pKa = 11.84YY123 pKa = 7.97HH124 pKa = 6.65TYY126 pKa = 11.0ARR128 pKa = 11.84FGIEE132 pKa = 3.48IQVQINPTPFQQGGLICAMVPGDD155 pKa = 3.54QSYY158 pKa = 11.41GSIASLTVYY167 pKa = 10.23PHH169 pKa = 7.13GLLNCNINNVVRR181 pKa = 11.84IKK183 pKa = 11.15VPFIYY188 pKa = 10.17TRR190 pKa = 11.84GAYY193 pKa = 9.37HH194 pKa = 6.91FKK196 pKa = 10.64DD197 pKa = 3.09PQYY200 pKa = 10.4PVWEE204 pKa = 3.91LTIRR208 pKa = 11.84VWSEE212 pKa = 3.37LNIGTGTSAYY222 pKa = 9.47TSLNVLARR230 pKa = 11.84FTDD233 pKa = 4.19LEE235 pKa = 4.31LHH237 pKa = 6.28GLTPLSTQMMRR248 pKa = 11.84NEE250 pKa = 4.03FRR252 pKa = 11.84VSTTEE257 pKa = 3.83NVVNLSNYY265 pKa = 8.88EE266 pKa = 3.81DD267 pKa = 3.93ARR269 pKa = 11.84AKK271 pKa = 10.21MSFALDD277 pKa = 3.51QEE279 pKa = 4.65DD280 pKa = 3.94WKK282 pKa = 11.24SDD284 pKa = 3.39PSQGGGIKK292 pKa = 8.51ITHH295 pKa = 5.72FTTWTSIPTLAAQFPFNASDD315 pKa = 4.41SVGQQIKK322 pKa = 10.03VIPVDD327 pKa = 3.6PYY329 pKa = 10.38FFQMTNTNPDD339 pKa = 3.47QKK341 pKa = 10.73CITALASICQMFCFWRR357 pKa = 11.84GDD359 pKa = 3.61LVFDD363 pKa = 4.06FQVFPTKK370 pKa = 10.24YY371 pKa = 9.54HH372 pKa = 5.82SGRR375 pKa = 11.84LLFCFVPGNEE385 pKa = 4.86LIDD388 pKa = 3.66VSGITLKK395 pKa = 10.66QATTAPCAVMDD406 pKa = 3.6ITGVQSTLRR415 pKa = 11.84FRR417 pKa = 11.84VPWISDD423 pKa = 2.97TPYY426 pKa = 10.39RR427 pKa = 11.84VNRR430 pKa = 11.84YY431 pKa = 6.49TKK433 pKa = 9.86SAHH436 pKa = 5.76QKK438 pKa = 10.74GEE440 pKa = 3.7YY441 pKa = 8.22TAIGKK446 pKa = 9.42LIVYY450 pKa = 8.22CYY452 pKa = 10.9NRR454 pKa = 11.84LTSPSNVASHH464 pKa = 5.77VRR466 pKa = 11.84VNVYY470 pKa = 10.22LSAINLEE477 pKa = 4.58CFAPLYY483 pKa = 10.49HH484 pKa = 7.66AMDD487 pKa = 3.5VTTQVGDD494 pKa = 3.63DD495 pKa = 3.49SGGFSTTVSTEE506 pKa = 3.7QNVPDD511 pKa = 4.31PQVGITTMKK520 pKa = 10.41DD521 pKa = 3.21LKK523 pKa = 11.11GKK525 pKa = 10.24ANRR528 pKa = 11.84GKK530 pKa = 9.4MDD532 pKa = 3.15VSGVQAPVGAITTIEE547 pKa = 4.25DD548 pKa = 3.35PVLAKK553 pKa = 10.15KK554 pKa = 10.74VPEE557 pKa = 4.28TFPEE561 pKa = 4.44LKK563 pKa = 10.02PGEE566 pKa = 4.25SRR568 pKa = 11.84HH569 pKa = 5.81TSDD572 pKa = 4.56HH573 pKa = 5.09MSIYY577 pKa = 10.64KK578 pKa = 10.23FMGRR582 pKa = 11.84SHH584 pKa = 7.38FLCTFTFNSNNKK596 pKa = 9.48EE597 pKa = 3.81YY598 pKa = 9.95TFPITLSSTSNPPHH612 pKa = 6.59GLPSTLRR619 pKa = 11.84WFFNLFQLYY628 pKa = 10.0RR629 pKa = 11.84GPLDD633 pKa = 3.25LTIIITGATDD643 pKa = 3.26VDD645 pKa = 3.6GMAWFTPVGLAVDD658 pKa = 4.26TPWVEE663 pKa = 4.14KK664 pKa = 10.65EE665 pKa = 3.95SALSIDD671 pKa = 3.78YY672 pKa = 7.9KK673 pKa = 9.97TALGAVRR680 pKa = 11.84FNTRR684 pKa = 11.84RR685 pKa = 11.84TGNIQIRR692 pKa = 11.84LPWYY696 pKa = 8.11SYY698 pKa = 11.06LYY700 pKa = 10.3AVSGALDD707 pKa = 3.65GLGDD711 pKa = 3.81KK712 pKa = 10.25TDD714 pKa = 3.47STFGLVSIQIANYY727 pKa = 8.73NHH729 pKa = 6.55SDD731 pKa = 3.43EE732 pKa = 4.56YY733 pKa = 11.63LSFSCYY739 pKa = 10.5LSVTEE744 pKa = 3.89QSEE747 pKa = 5.61FYY749 pKa = 10.61FPRR752 pKa = 11.84APLNSNAMLSTEE764 pKa = 3.91SMMSRR769 pKa = 11.84IAAGDD774 pKa = 3.91LEE776 pKa = 4.88SSVDD780 pKa = 3.72DD781 pKa = 4.29PRR783 pKa = 11.84SEE785 pKa = 3.69EE786 pKa = 3.95DD787 pKa = 3.65KK788 pKa = 10.94RR789 pKa = 11.84FEE791 pKa = 4.19SHH793 pKa = 6.18IEE795 pKa = 3.56CRR797 pKa = 11.84KK798 pKa = 9.11PYY800 pKa = 10.24KK801 pKa = 9.82EE802 pKa = 4.21LRR804 pKa = 11.84LEE806 pKa = 4.13VGKK809 pKa = 10.23QRR811 pKa = 11.84LKK813 pKa = 10.51YY814 pKa = 10.03AQEE817 pKa = 3.9EE818 pKa = 4.43LSNEE822 pKa = 4.07VLPPPRR828 pKa = 11.84KK829 pKa = 9.0MKK831 pKa = 10.78GLFSQAKK838 pKa = 8.36ISLFYY843 pKa = 10.6TEE845 pKa = 4.39EE846 pKa = 4.3HH847 pKa = 6.99EE848 pKa = 4.37IMKK851 pKa = 9.4FSWRR855 pKa = 11.84GVTADD860 pKa = 3.19TRR862 pKa = 11.84ALRR865 pKa = 11.84RR866 pKa = 11.84FGFSLAAGRR875 pKa = 11.84SVWTLEE881 pKa = 3.44MDD883 pKa = 3.62AGVLTGRR890 pKa = 11.84LIRR893 pKa = 11.84LNDD896 pKa = 3.78EE897 pKa = 4.14KK898 pKa = 9.81WTEE901 pKa = 3.96MKK903 pKa = 10.35DD904 pKa = 3.58DD905 pKa = 5.08KK906 pKa = 10.93IVSLIEE912 pKa = 3.92KK913 pKa = 7.79FTSNKK918 pKa = 9.28YY919 pKa = 6.88WSKK922 pKa = 11.09VNFPHH927 pKa = 7.25GMLDD931 pKa = 3.83LEE933 pKa = 4.68EE934 pKa = 4.31IAANSKK940 pKa = 10.42DD941 pKa = 3.87FPNMSEE947 pKa = 3.89TDD949 pKa = 3.67LCFLLHH955 pKa = 6.48WLNPKK960 pKa = 9.86KK961 pKa = 10.48INLADD966 pKa = 3.9RR967 pKa = 11.84MLGLSGVQEE976 pKa = 3.98IKK978 pKa = 10.46EE979 pKa = 4.0QGVGLIAEE987 pKa = 4.75CRR989 pKa = 11.84TFLDD993 pKa = 4.81SIAGTLKK1000 pKa = 10.61SMMFGFHH1007 pKa = 6.6HH1008 pKa = 6.62SVTVEE1013 pKa = 4.11IINTVLCFVKK1023 pKa = 10.52SGILLYY1029 pKa = 10.66VIQQLNQDD1037 pKa = 3.81EE1038 pKa = 4.49HH1039 pKa = 7.24SHH1041 pKa = 6.79IIGLLRR1047 pKa = 11.84VMNYY1051 pKa = 10.7ADD1053 pKa = 4.05IGCSVISCGKK1063 pKa = 9.71VFSKK1067 pKa = 10.4MLEE1070 pKa = 4.4TVFNWQMDD1078 pKa = 3.75SRR1080 pKa = 11.84MMEE1083 pKa = 3.98LRR1085 pKa = 11.84TQSFSNWLRR1094 pKa = 11.84DD1095 pKa = 3.15ICSGITIFKK1104 pKa = 9.74NFKK1107 pKa = 10.12DD1108 pKa = 4.0AIYY1111 pKa = 10.26WLYY1114 pKa = 10.87TKK1116 pKa = 10.77LKK1118 pKa = 10.44DD1119 pKa = 4.14FYY1121 pKa = 10.87EE1122 pKa = 4.21VNYY1125 pKa = 10.3GKK1127 pKa = 10.55KK1128 pKa = 9.81KK1129 pKa = 10.75DD1130 pKa = 3.54ILNILKK1136 pKa = 10.43DD1137 pKa = 3.72NQQKK1141 pKa = 9.65IEE1143 pKa = 4.04KK1144 pKa = 9.51AIEE1147 pKa = 3.86EE1148 pKa = 4.05ADD1150 pKa = 3.9EE1151 pKa = 4.44FCILQIQDD1159 pKa = 3.32VEE1161 pKa = 4.79KK1162 pKa = 10.86FEE1164 pKa = 4.51QYY1166 pKa = 10.51QKK1168 pKa = 11.31GVDD1171 pKa = 4.74LIQKK1175 pKa = 9.55LRR1177 pKa = 11.84TVHH1180 pKa = 6.8SMAQVDD1186 pKa = 4.3PNLMVHH1192 pKa = 6.81LSPLRR1197 pKa = 11.84DD1198 pKa = 3.95CIARR1202 pKa = 11.84VHH1204 pKa = 6.07QKK1206 pKa = 10.52LKK1208 pKa = 10.87NLGSINQAMVTRR1220 pKa = 11.84CEE1222 pKa = 3.84PVVCYY1227 pKa = 10.21LYY1229 pKa = 10.94GKK1231 pKa = 10.18RR1232 pKa = 11.84GGGKK1236 pKa = 9.51SLTSIALATKK1246 pKa = 8.82ICKK1249 pKa = 10.0HH1250 pKa = 5.98YY1251 pKa = 10.75GVEE1254 pKa = 4.1PEE1256 pKa = 4.04KK1257 pKa = 11.11NIYY1260 pKa = 7.41TKK1262 pKa = 10.52PVASDD1267 pKa = 3.2YY1268 pKa = 10.42WDD1270 pKa = 4.48GYY1272 pKa = 10.74SGQLVCIIDD1281 pKa = 5.5DD1282 pKa = 3.62IGQNTTDD1289 pKa = 4.05EE1290 pKa = 4.46DD1291 pKa = 3.64WSDD1294 pKa = 3.53FCQLVSGCPMRR1305 pKa = 11.84LNMASLEE1312 pKa = 4.23EE1313 pKa = 4.19KK1314 pKa = 10.26GRR1316 pKa = 11.84HH1317 pKa = 4.88FSSPFIIATSNWSNPSPKK1335 pKa = 9.3TVYY1338 pKa = 10.25VKK1340 pKa = 10.45EE1341 pKa = 4.52AIDD1344 pKa = 3.44RR1345 pKa = 11.84RR1346 pKa = 11.84LHH1348 pKa = 5.88FKK1350 pKa = 11.24VEE1352 pKa = 4.06VKK1354 pKa = 9.93PASFFKK1360 pKa = 10.91NPHH1363 pKa = 5.68NDD1365 pKa = 3.15MLNVNLAKK1373 pKa = 10.36TNDD1376 pKa = 3.93AIKK1379 pKa = 10.96DD1380 pKa = 3.69MSCVDD1385 pKa = 5.88LIMDD1389 pKa = 3.94GHH1391 pKa = 6.11NVSLMDD1397 pKa = 4.39LLSSLVMTVEE1407 pKa = 3.7IRR1409 pKa = 11.84KK1410 pKa = 9.41QNMTEE1415 pKa = 4.95FMEE1418 pKa = 4.63LWSQGISDD1426 pKa = 5.43DD1427 pKa = 4.92DD1428 pKa = 4.08NDD1430 pKa = 3.95SAVAEE1435 pKa = 4.63FFQSFPSGEE1444 pKa = 3.99PSNSKK1449 pKa = 10.64LSGFFQSVTNHH1460 pKa = 4.72KK1461 pKa = 8.8WVAVGAAVGILGVLVGGWFVYY1482 pKa = 10.39KK1483 pKa = 10.44HH1484 pKa = 6.05FSRR1487 pKa = 11.84KK1488 pKa = 8.57EE1489 pKa = 3.87EE1490 pKa = 3.92EE1491 pKa = 4.74PIPAEE1496 pKa = 4.07GVYY1499 pKa = 10.54HH1500 pKa = 7.09GVTKK1504 pKa = 10.25PKK1506 pKa = 10.51QVIKK1510 pKa = 10.88LDD1512 pKa = 3.9ADD1514 pKa = 3.68PVEE1517 pKa = 4.51SQSTLEE1523 pKa = 3.79IAGLVRR1529 pKa = 11.84KK1530 pKa = 9.84NLVQFGVGEE1539 pKa = 4.1KK1540 pKa = 9.74NGCVRR1545 pKa = 11.84WVMNALGVKK1554 pKa = 9.97DD1555 pKa = 4.4DD1556 pKa = 3.64WLLVPSHH1563 pKa = 6.88AYY1565 pKa = 9.71KK1566 pKa = 10.63FEE1568 pKa = 4.44KK1569 pKa = 9.99DD1570 pKa = 3.45YY1571 pKa = 11.65EE1572 pKa = 4.18MMEE1575 pKa = 4.53FYY1577 pKa = 10.69FNRR1580 pKa = 11.84GGTYY1584 pKa = 10.33YY1585 pKa = 10.58SISAGNVVIQSLDD1598 pKa = 3.22VGFQDD1603 pKa = 3.47VVLMKK1608 pKa = 10.71VPTIPKK1614 pKa = 9.58FRR1616 pKa = 11.84DD1617 pKa = 3.0ITQHH1621 pKa = 6.46FIKK1624 pKa = 10.64KK1625 pKa = 9.89GDD1627 pKa = 3.48VPRR1630 pKa = 11.84ALNRR1634 pKa = 11.84LATLVTTVNGTPMLISEE1651 pKa = 5.25GPLKK1655 pKa = 10.26MEE1657 pKa = 4.43EE1658 pKa = 4.05KK1659 pKa = 9.81ATYY1662 pKa = 7.95VHH1664 pKa = 6.78KK1665 pKa = 11.07KK1666 pKa = 10.44NDD1668 pKa = 3.47GTTVDD1673 pKa = 4.14LTVDD1677 pKa = 3.38QAWRR1681 pKa = 11.84GKK1683 pKa = 10.89GEE1685 pKa = 4.48GLPGMCGGALVSSNQSIQNAILGIHH1710 pKa = 5.3VAGGNSILVAKK1721 pKa = 10.41LVTQEE1726 pKa = 3.76MFQNIDD1732 pKa = 3.41KK1733 pKa = 10.51KK1734 pKa = 10.82IEE1736 pKa = 3.87SQRR1739 pKa = 11.84IMKK1742 pKa = 9.93VEE1744 pKa = 4.37FTQCSMNVVSKK1755 pKa = 9.45TLFRR1759 pKa = 11.84KK1760 pKa = 10.04SPIYY1764 pKa = 10.35HH1765 pKa = 6.98HH1766 pKa = 7.17IDD1768 pKa = 2.63KK1769 pKa = 11.0TMINFPAAMPFSKK1782 pKa = 11.17AEE1784 pKa = 4.0IDD1786 pKa = 3.63PMAVMLSKK1794 pKa = 10.95YY1795 pKa = 9.9SLPIVEE1801 pKa = 4.68EE1802 pKa = 4.27PEE1804 pKa = 4.19DD1805 pKa = 3.76YY1806 pKa = 10.96KK1807 pKa = 11.05EE1808 pKa = 5.06ASIFYY1813 pKa = 9.6QNKK1816 pKa = 9.36IVGKK1820 pKa = 7.17TQLVDD1825 pKa = 4.14DD1826 pKa = 4.9FLDD1829 pKa = 4.4LDD1831 pKa = 3.97MAITGAPGIDD1841 pKa = 4.57AINMDD1846 pKa = 4.39SSPGFPYY1853 pKa = 10.56VQEE1856 pKa = 4.41KK1857 pKa = 8.32LTKK1860 pKa = 9.76RR1861 pKa = 11.84DD1862 pKa = 4.55LIWLDD1867 pKa = 3.71EE1868 pKa = 4.36NGLLLGVHH1876 pKa = 6.56PRR1878 pKa = 11.84LAQRR1882 pKa = 11.84ILFNTVMMEE1891 pKa = 3.9NCSDD1895 pKa = 4.05LDD1897 pKa = 4.05VVFTTCPKK1905 pKa = 10.94DD1906 pKa = 3.44EE1907 pKa = 4.6LRR1909 pKa = 11.84PLEE1912 pKa = 4.55KK1913 pKa = 10.58VLEE1916 pKa = 4.47SKK1918 pKa = 9.24TRR1920 pKa = 11.84AIDD1923 pKa = 3.68ACPLDD1928 pKa = 4.13YY1929 pKa = 11.11SILCRR1934 pKa = 11.84MYY1936 pKa = 8.4WGPAISYY1943 pKa = 7.87FHH1945 pKa = 7.06LNPGFHH1951 pKa = 6.4TGVAIGIDD1959 pKa = 4.14PDD1961 pKa = 3.96RR1962 pKa = 11.84QWDD1965 pKa = 3.85EE1966 pKa = 4.09LFKK1969 pKa = 10.92TMIRR1973 pKa = 11.84FGDD1976 pKa = 3.43VGLDD1980 pKa = 3.39LDD1982 pKa = 5.24FSAFDD1987 pKa = 3.68ASLSPFMIRR1996 pKa = 11.84EE1997 pKa = 4.08AGRR2000 pKa = 11.84IMSEE2004 pKa = 3.88LSGTPSHH2011 pKa = 7.41FGTALINTIIYY2022 pKa = 10.05SKK2024 pKa = 10.68HH2025 pKa = 6.0LLYY2028 pKa = 10.71NCCYY2032 pKa = 8.98HH2033 pKa = 6.37VCGSMPSGSPCTALLNSIINNVNLYY2058 pKa = 10.36YY2059 pKa = 10.73VFSKK2063 pKa = 10.62IFGKK2067 pKa = 10.64SPVFFCQALKK2077 pKa = 10.31ILCYY2081 pKa = 10.51GDD2083 pKa = 4.66DD2084 pKa = 3.66VLIVFSRR2091 pKa = 11.84DD2092 pKa = 3.43VQIDD2096 pKa = 3.57NLDD2099 pKa = 4.42LIGQKK2104 pKa = 9.82IVDD2107 pKa = 3.97EE2108 pKa = 4.63FKK2110 pKa = 11.03KK2111 pKa = 10.82LGMTATSADD2120 pKa = 3.6KK2121 pKa = 10.76NVPQLKK2127 pKa = 9.45PVSEE2131 pKa = 4.13LTFLKK2136 pKa = 10.52RR2137 pKa = 11.84SFNLVEE2143 pKa = 4.08DD2144 pKa = 5.08RR2145 pKa = 11.84IRR2147 pKa = 11.84PAISEE2152 pKa = 4.08KK2153 pKa = 10.43TIWSLIAWQRR2163 pKa = 11.84SNAEE2167 pKa = 3.8FEE2169 pKa = 4.51QNLEE2173 pKa = 3.9NAQWFAFMHH2182 pKa = 6.63GYY2184 pKa = 10.06EE2185 pKa = 5.06FYY2187 pKa = 10.77QKK2189 pKa = 10.25FYY2191 pKa = 11.28YY2192 pKa = 10.23FVQSCLEE2199 pKa = 3.98KK2200 pKa = 11.07EE2201 pKa = 4.19MIEE2204 pKa = 4.12YY2205 pKa = 10.42RR2206 pKa = 11.84LKK2208 pKa = 11.06SYY2210 pKa = 10.5DD2211 pKa = 2.63WWRR2214 pKa = 11.84MRR2216 pKa = 11.84FYY2218 pKa = 10.36DD2219 pKa = 3.66QCFICDD2225 pKa = 3.94LSS2227 pKa = 3.54
MM1 pKa = 7.18NMSRR5 pKa = 11.84QGIFQTVGSGLDD17 pKa = 4.01HH18 pKa = 6.92ILSLADD24 pKa = 3.29IEE26 pKa = 4.36EE27 pKa = 4.16EE28 pKa = 4.58QMIQSVDD35 pKa = 3.17RR36 pKa = 11.84TAVTGASYY44 pKa = 7.83FTSVDD49 pKa = 3.17QSSVHH54 pKa = 4.42TAEE57 pKa = 4.41VGSHH61 pKa = 4.06QVEE64 pKa = 4.31PLRR67 pKa = 11.84TSVDD71 pKa = 3.18KK72 pKa = 11.07PGSKK76 pKa = 8.56KK77 pKa = 8.1TQGEE81 pKa = 4.49KK82 pKa = 10.68FFLIHH87 pKa = 6.17SADD90 pKa = 3.33WLTTHH95 pKa = 7.47ALFHH99 pKa = 6.33EE100 pKa = 4.75VAKK103 pKa = 10.89LDD105 pKa = 4.08VVKK108 pKa = 10.69LLYY111 pKa = 10.5NEE113 pKa = 3.96QFAVQGLLRR122 pKa = 11.84YY123 pKa = 7.97HH124 pKa = 6.65TYY126 pKa = 11.0ARR128 pKa = 11.84FGIEE132 pKa = 3.48IQVQINPTPFQQGGLICAMVPGDD155 pKa = 3.54QSYY158 pKa = 11.41GSIASLTVYY167 pKa = 10.23PHH169 pKa = 7.13GLLNCNINNVVRR181 pKa = 11.84IKK183 pKa = 11.15VPFIYY188 pKa = 10.17TRR190 pKa = 11.84GAYY193 pKa = 9.37HH194 pKa = 6.91FKK196 pKa = 10.64DD197 pKa = 3.09PQYY200 pKa = 10.4PVWEE204 pKa = 3.91LTIRR208 pKa = 11.84VWSEE212 pKa = 3.37LNIGTGTSAYY222 pKa = 9.47TSLNVLARR230 pKa = 11.84FTDD233 pKa = 4.19LEE235 pKa = 4.31LHH237 pKa = 6.28GLTPLSTQMMRR248 pKa = 11.84NEE250 pKa = 4.03FRR252 pKa = 11.84VSTTEE257 pKa = 3.83NVVNLSNYY265 pKa = 8.88EE266 pKa = 3.81DD267 pKa = 3.93ARR269 pKa = 11.84AKK271 pKa = 10.21MSFALDD277 pKa = 3.51QEE279 pKa = 4.65DD280 pKa = 3.94WKK282 pKa = 11.24SDD284 pKa = 3.39PSQGGGIKK292 pKa = 8.51ITHH295 pKa = 5.72FTTWTSIPTLAAQFPFNASDD315 pKa = 4.41SVGQQIKK322 pKa = 10.03VIPVDD327 pKa = 3.6PYY329 pKa = 10.38FFQMTNTNPDD339 pKa = 3.47QKK341 pKa = 10.73CITALASICQMFCFWRR357 pKa = 11.84GDD359 pKa = 3.61LVFDD363 pKa = 4.06FQVFPTKK370 pKa = 10.24YY371 pKa = 9.54HH372 pKa = 5.82SGRR375 pKa = 11.84LLFCFVPGNEE385 pKa = 4.86LIDD388 pKa = 3.66VSGITLKK395 pKa = 10.66QATTAPCAVMDD406 pKa = 3.6ITGVQSTLRR415 pKa = 11.84FRR417 pKa = 11.84VPWISDD423 pKa = 2.97TPYY426 pKa = 10.39RR427 pKa = 11.84VNRR430 pKa = 11.84YY431 pKa = 6.49TKK433 pKa = 9.86SAHH436 pKa = 5.76QKK438 pKa = 10.74GEE440 pKa = 3.7YY441 pKa = 8.22TAIGKK446 pKa = 9.42LIVYY450 pKa = 8.22CYY452 pKa = 10.9NRR454 pKa = 11.84LTSPSNVASHH464 pKa = 5.77VRR466 pKa = 11.84VNVYY470 pKa = 10.22LSAINLEE477 pKa = 4.58CFAPLYY483 pKa = 10.49HH484 pKa = 7.66AMDD487 pKa = 3.5VTTQVGDD494 pKa = 3.63DD495 pKa = 3.49SGGFSTTVSTEE506 pKa = 3.7QNVPDD511 pKa = 4.31PQVGITTMKK520 pKa = 10.41DD521 pKa = 3.21LKK523 pKa = 11.11GKK525 pKa = 10.24ANRR528 pKa = 11.84GKK530 pKa = 9.4MDD532 pKa = 3.15VSGVQAPVGAITTIEE547 pKa = 4.25DD548 pKa = 3.35PVLAKK553 pKa = 10.15KK554 pKa = 10.74VPEE557 pKa = 4.28TFPEE561 pKa = 4.44LKK563 pKa = 10.02PGEE566 pKa = 4.25SRR568 pKa = 11.84HH569 pKa = 5.81TSDD572 pKa = 4.56HH573 pKa = 5.09MSIYY577 pKa = 10.64KK578 pKa = 10.23FMGRR582 pKa = 11.84SHH584 pKa = 7.38FLCTFTFNSNNKK596 pKa = 9.48EE597 pKa = 3.81YY598 pKa = 9.95TFPITLSSTSNPPHH612 pKa = 6.59GLPSTLRR619 pKa = 11.84WFFNLFQLYY628 pKa = 10.0RR629 pKa = 11.84GPLDD633 pKa = 3.25LTIIITGATDD643 pKa = 3.26VDD645 pKa = 3.6GMAWFTPVGLAVDD658 pKa = 4.26TPWVEE663 pKa = 4.14KK664 pKa = 10.65EE665 pKa = 3.95SALSIDD671 pKa = 3.78YY672 pKa = 7.9KK673 pKa = 9.97TALGAVRR680 pKa = 11.84FNTRR684 pKa = 11.84RR685 pKa = 11.84TGNIQIRR692 pKa = 11.84LPWYY696 pKa = 8.11SYY698 pKa = 11.06LYY700 pKa = 10.3AVSGALDD707 pKa = 3.65GLGDD711 pKa = 3.81KK712 pKa = 10.25TDD714 pKa = 3.47STFGLVSIQIANYY727 pKa = 8.73NHH729 pKa = 6.55SDD731 pKa = 3.43EE732 pKa = 4.56YY733 pKa = 11.63LSFSCYY739 pKa = 10.5LSVTEE744 pKa = 3.89QSEE747 pKa = 5.61FYY749 pKa = 10.61FPRR752 pKa = 11.84APLNSNAMLSTEE764 pKa = 3.91SMMSRR769 pKa = 11.84IAAGDD774 pKa = 3.91LEE776 pKa = 4.88SSVDD780 pKa = 3.72DD781 pKa = 4.29PRR783 pKa = 11.84SEE785 pKa = 3.69EE786 pKa = 3.95DD787 pKa = 3.65KK788 pKa = 10.94RR789 pKa = 11.84FEE791 pKa = 4.19SHH793 pKa = 6.18IEE795 pKa = 3.56CRR797 pKa = 11.84KK798 pKa = 9.11PYY800 pKa = 10.24KK801 pKa = 9.82EE802 pKa = 4.21LRR804 pKa = 11.84LEE806 pKa = 4.13VGKK809 pKa = 10.23QRR811 pKa = 11.84LKK813 pKa = 10.51YY814 pKa = 10.03AQEE817 pKa = 3.9EE818 pKa = 4.43LSNEE822 pKa = 4.07VLPPPRR828 pKa = 11.84KK829 pKa = 9.0MKK831 pKa = 10.78GLFSQAKK838 pKa = 8.36ISLFYY843 pKa = 10.6TEE845 pKa = 4.39EE846 pKa = 4.3HH847 pKa = 6.99EE848 pKa = 4.37IMKK851 pKa = 9.4FSWRR855 pKa = 11.84GVTADD860 pKa = 3.19TRR862 pKa = 11.84ALRR865 pKa = 11.84RR866 pKa = 11.84FGFSLAAGRR875 pKa = 11.84SVWTLEE881 pKa = 3.44MDD883 pKa = 3.62AGVLTGRR890 pKa = 11.84LIRR893 pKa = 11.84LNDD896 pKa = 3.78EE897 pKa = 4.14KK898 pKa = 9.81WTEE901 pKa = 3.96MKK903 pKa = 10.35DD904 pKa = 3.58DD905 pKa = 5.08KK906 pKa = 10.93IVSLIEE912 pKa = 3.92KK913 pKa = 7.79FTSNKK918 pKa = 9.28YY919 pKa = 6.88WSKK922 pKa = 11.09VNFPHH927 pKa = 7.25GMLDD931 pKa = 3.83LEE933 pKa = 4.68EE934 pKa = 4.31IAANSKK940 pKa = 10.42DD941 pKa = 3.87FPNMSEE947 pKa = 3.89TDD949 pKa = 3.67LCFLLHH955 pKa = 6.48WLNPKK960 pKa = 9.86KK961 pKa = 10.48INLADD966 pKa = 3.9RR967 pKa = 11.84MLGLSGVQEE976 pKa = 3.98IKK978 pKa = 10.46EE979 pKa = 4.0QGVGLIAEE987 pKa = 4.75CRR989 pKa = 11.84TFLDD993 pKa = 4.81SIAGTLKK1000 pKa = 10.61SMMFGFHH1007 pKa = 6.6HH1008 pKa = 6.62SVTVEE1013 pKa = 4.11IINTVLCFVKK1023 pKa = 10.52SGILLYY1029 pKa = 10.66VIQQLNQDD1037 pKa = 3.81EE1038 pKa = 4.49HH1039 pKa = 7.24SHH1041 pKa = 6.79IIGLLRR1047 pKa = 11.84VMNYY1051 pKa = 10.7ADD1053 pKa = 4.05IGCSVISCGKK1063 pKa = 9.71VFSKK1067 pKa = 10.4MLEE1070 pKa = 4.4TVFNWQMDD1078 pKa = 3.75SRR1080 pKa = 11.84MMEE1083 pKa = 3.98LRR1085 pKa = 11.84TQSFSNWLRR1094 pKa = 11.84DD1095 pKa = 3.15ICSGITIFKK1104 pKa = 9.74NFKK1107 pKa = 10.12DD1108 pKa = 4.0AIYY1111 pKa = 10.26WLYY1114 pKa = 10.87TKK1116 pKa = 10.77LKK1118 pKa = 10.44DD1119 pKa = 4.14FYY1121 pKa = 10.87EE1122 pKa = 4.21VNYY1125 pKa = 10.3GKK1127 pKa = 10.55KK1128 pKa = 9.81KK1129 pKa = 10.75DD1130 pKa = 3.54ILNILKK1136 pKa = 10.43DD1137 pKa = 3.72NQQKK1141 pKa = 9.65IEE1143 pKa = 4.04KK1144 pKa = 9.51AIEE1147 pKa = 3.86EE1148 pKa = 4.05ADD1150 pKa = 3.9EE1151 pKa = 4.44FCILQIQDD1159 pKa = 3.32VEE1161 pKa = 4.79KK1162 pKa = 10.86FEE1164 pKa = 4.51QYY1166 pKa = 10.51QKK1168 pKa = 11.31GVDD1171 pKa = 4.74LIQKK1175 pKa = 9.55LRR1177 pKa = 11.84TVHH1180 pKa = 6.8SMAQVDD1186 pKa = 4.3PNLMVHH1192 pKa = 6.81LSPLRR1197 pKa = 11.84DD1198 pKa = 3.95CIARR1202 pKa = 11.84VHH1204 pKa = 6.07QKK1206 pKa = 10.52LKK1208 pKa = 10.87NLGSINQAMVTRR1220 pKa = 11.84CEE1222 pKa = 3.84PVVCYY1227 pKa = 10.21LYY1229 pKa = 10.94GKK1231 pKa = 10.18RR1232 pKa = 11.84GGGKK1236 pKa = 9.51SLTSIALATKK1246 pKa = 8.82ICKK1249 pKa = 10.0HH1250 pKa = 5.98YY1251 pKa = 10.75GVEE1254 pKa = 4.1PEE1256 pKa = 4.04KK1257 pKa = 11.11NIYY1260 pKa = 7.41TKK1262 pKa = 10.52PVASDD1267 pKa = 3.2YY1268 pKa = 10.42WDD1270 pKa = 4.48GYY1272 pKa = 10.74SGQLVCIIDD1281 pKa = 5.5DD1282 pKa = 3.62IGQNTTDD1289 pKa = 4.05EE1290 pKa = 4.46DD1291 pKa = 3.64WSDD1294 pKa = 3.53FCQLVSGCPMRR1305 pKa = 11.84LNMASLEE1312 pKa = 4.23EE1313 pKa = 4.19KK1314 pKa = 10.26GRR1316 pKa = 11.84HH1317 pKa = 4.88FSSPFIIATSNWSNPSPKK1335 pKa = 9.3TVYY1338 pKa = 10.25VKK1340 pKa = 10.45EE1341 pKa = 4.52AIDD1344 pKa = 3.44RR1345 pKa = 11.84RR1346 pKa = 11.84LHH1348 pKa = 5.88FKK1350 pKa = 11.24VEE1352 pKa = 4.06VKK1354 pKa = 9.93PASFFKK1360 pKa = 10.91NPHH1363 pKa = 5.68NDD1365 pKa = 3.15MLNVNLAKK1373 pKa = 10.36TNDD1376 pKa = 3.93AIKK1379 pKa = 10.96DD1380 pKa = 3.69MSCVDD1385 pKa = 5.88LIMDD1389 pKa = 3.94GHH1391 pKa = 6.11NVSLMDD1397 pKa = 4.39LLSSLVMTVEE1407 pKa = 3.7IRR1409 pKa = 11.84KK1410 pKa = 9.41QNMTEE1415 pKa = 4.95FMEE1418 pKa = 4.63LWSQGISDD1426 pKa = 5.43DD1427 pKa = 4.92DD1428 pKa = 4.08NDD1430 pKa = 3.95SAVAEE1435 pKa = 4.63FFQSFPSGEE1444 pKa = 3.99PSNSKK1449 pKa = 10.64LSGFFQSVTNHH1460 pKa = 4.72KK1461 pKa = 8.8WVAVGAAVGILGVLVGGWFVYY1482 pKa = 10.39KK1483 pKa = 10.44HH1484 pKa = 6.05FSRR1487 pKa = 11.84KK1488 pKa = 8.57EE1489 pKa = 3.87EE1490 pKa = 3.92EE1491 pKa = 4.74PIPAEE1496 pKa = 4.07GVYY1499 pKa = 10.54HH1500 pKa = 7.09GVTKK1504 pKa = 10.25PKK1506 pKa = 10.51QVIKK1510 pKa = 10.88LDD1512 pKa = 3.9ADD1514 pKa = 3.68PVEE1517 pKa = 4.51SQSTLEE1523 pKa = 3.79IAGLVRR1529 pKa = 11.84KK1530 pKa = 9.84NLVQFGVGEE1539 pKa = 4.1KK1540 pKa = 9.74NGCVRR1545 pKa = 11.84WVMNALGVKK1554 pKa = 9.97DD1555 pKa = 4.4DD1556 pKa = 3.64WLLVPSHH1563 pKa = 6.88AYY1565 pKa = 9.71KK1566 pKa = 10.63FEE1568 pKa = 4.44KK1569 pKa = 9.99DD1570 pKa = 3.45YY1571 pKa = 11.65EE1572 pKa = 4.18MMEE1575 pKa = 4.53FYY1577 pKa = 10.69FNRR1580 pKa = 11.84GGTYY1584 pKa = 10.33YY1585 pKa = 10.58SISAGNVVIQSLDD1598 pKa = 3.22VGFQDD1603 pKa = 3.47VVLMKK1608 pKa = 10.71VPTIPKK1614 pKa = 9.58FRR1616 pKa = 11.84DD1617 pKa = 3.0ITQHH1621 pKa = 6.46FIKK1624 pKa = 10.64KK1625 pKa = 9.89GDD1627 pKa = 3.48VPRR1630 pKa = 11.84ALNRR1634 pKa = 11.84LATLVTTVNGTPMLISEE1651 pKa = 5.25GPLKK1655 pKa = 10.26MEE1657 pKa = 4.43EE1658 pKa = 4.05KK1659 pKa = 9.81ATYY1662 pKa = 7.95VHH1664 pKa = 6.78KK1665 pKa = 11.07KK1666 pKa = 10.44NDD1668 pKa = 3.47GTTVDD1673 pKa = 4.14LTVDD1677 pKa = 3.38QAWRR1681 pKa = 11.84GKK1683 pKa = 10.89GEE1685 pKa = 4.48GLPGMCGGALVSSNQSIQNAILGIHH1710 pKa = 5.3VAGGNSILVAKK1721 pKa = 10.41LVTQEE1726 pKa = 3.76MFQNIDD1732 pKa = 3.41KK1733 pKa = 10.51KK1734 pKa = 10.82IEE1736 pKa = 3.87SQRR1739 pKa = 11.84IMKK1742 pKa = 9.93VEE1744 pKa = 4.37FTQCSMNVVSKK1755 pKa = 9.45TLFRR1759 pKa = 11.84KK1760 pKa = 10.04SPIYY1764 pKa = 10.35HH1765 pKa = 6.98HH1766 pKa = 7.17IDD1768 pKa = 2.63KK1769 pKa = 11.0TMINFPAAMPFSKK1782 pKa = 11.17AEE1784 pKa = 4.0IDD1786 pKa = 3.63PMAVMLSKK1794 pKa = 10.95YY1795 pKa = 9.9SLPIVEE1801 pKa = 4.68EE1802 pKa = 4.27PEE1804 pKa = 4.19DD1805 pKa = 3.76YY1806 pKa = 10.96KK1807 pKa = 11.05EE1808 pKa = 5.06ASIFYY1813 pKa = 9.6QNKK1816 pKa = 9.36IVGKK1820 pKa = 7.17TQLVDD1825 pKa = 4.14DD1826 pKa = 4.9FLDD1829 pKa = 4.4LDD1831 pKa = 3.97MAITGAPGIDD1841 pKa = 4.57AINMDD1846 pKa = 4.39SSPGFPYY1853 pKa = 10.56VQEE1856 pKa = 4.41KK1857 pKa = 8.32LTKK1860 pKa = 9.76RR1861 pKa = 11.84DD1862 pKa = 4.55LIWLDD1867 pKa = 3.71EE1868 pKa = 4.36NGLLLGVHH1876 pKa = 6.56PRR1878 pKa = 11.84LAQRR1882 pKa = 11.84ILFNTVMMEE1891 pKa = 3.9NCSDD1895 pKa = 4.05LDD1897 pKa = 4.05VVFTTCPKK1905 pKa = 10.94DD1906 pKa = 3.44EE1907 pKa = 4.6LRR1909 pKa = 11.84PLEE1912 pKa = 4.55KK1913 pKa = 10.58VLEE1916 pKa = 4.47SKK1918 pKa = 9.24TRR1920 pKa = 11.84AIDD1923 pKa = 3.68ACPLDD1928 pKa = 4.13YY1929 pKa = 11.11SILCRR1934 pKa = 11.84MYY1936 pKa = 8.4WGPAISYY1943 pKa = 7.87FHH1945 pKa = 7.06LNPGFHH1951 pKa = 6.4TGVAIGIDD1959 pKa = 4.14PDD1961 pKa = 3.96RR1962 pKa = 11.84QWDD1965 pKa = 3.85EE1966 pKa = 4.09LFKK1969 pKa = 10.92TMIRR1973 pKa = 11.84FGDD1976 pKa = 3.43VGLDD1980 pKa = 3.39LDD1982 pKa = 5.24FSAFDD1987 pKa = 3.68ASLSPFMIRR1996 pKa = 11.84EE1997 pKa = 4.08AGRR2000 pKa = 11.84IMSEE2004 pKa = 3.88LSGTPSHH2011 pKa = 7.41FGTALINTIIYY2022 pKa = 10.05SKK2024 pKa = 10.68HH2025 pKa = 6.0LLYY2028 pKa = 10.71NCCYY2032 pKa = 8.98HH2033 pKa = 6.37VCGSMPSGSPCTALLNSIINNVNLYY2058 pKa = 10.36YY2059 pKa = 10.73VFSKK2063 pKa = 10.62IFGKK2067 pKa = 10.64SPVFFCQALKK2077 pKa = 10.31ILCYY2081 pKa = 10.51GDD2083 pKa = 4.66DD2084 pKa = 3.66VLIVFSRR2091 pKa = 11.84DD2092 pKa = 3.43VQIDD2096 pKa = 3.57NLDD2099 pKa = 4.42LIGQKK2104 pKa = 9.82IVDD2107 pKa = 3.97EE2108 pKa = 4.63FKK2110 pKa = 11.03KK2111 pKa = 10.82LGMTATSADD2120 pKa = 3.6KK2121 pKa = 10.76NVPQLKK2127 pKa = 9.45PVSEE2131 pKa = 4.13LTFLKK2136 pKa = 10.52RR2137 pKa = 11.84SFNLVEE2143 pKa = 4.08DD2144 pKa = 5.08RR2145 pKa = 11.84IRR2147 pKa = 11.84PAISEE2152 pKa = 4.08KK2153 pKa = 10.43TIWSLIAWQRR2163 pKa = 11.84SNAEE2167 pKa = 3.8FEE2169 pKa = 4.51QNLEE2173 pKa = 3.9NAQWFAFMHH2182 pKa = 6.63GYY2184 pKa = 10.06EE2185 pKa = 5.06FYY2187 pKa = 10.77QKK2189 pKa = 10.25FYY2191 pKa = 11.28YY2192 pKa = 10.23FVQSCLEE2199 pKa = 3.98KK2200 pKa = 11.07EE2201 pKa = 4.19MIEE2204 pKa = 4.12YY2205 pKa = 10.42RR2206 pKa = 11.84LKK2208 pKa = 11.06SYY2210 pKa = 10.5DD2211 pKa = 2.63WWRR2214 pKa = 11.84MRR2216 pKa = 11.84FYY2218 pKa = 10.36DD2219 pKa = 3.66QCFICDD2225 pKa = 3.94LSS2227 pKa = 3.54
Molecular weight: 251.51 kDa
Isoelectric point according different methods:
Protein with the highest isoelectric point:
>sp|P08617|POLG_HAVHM Genome polyprotein OS=Human hepatitis A virus genotype IB (isolate HM175) OX=12098 PE=1 SV=1
MM1 pKa = 7.18NMSRR5 pKa = 11.84QGIFQTVGSGLDD17 pKa = 4.01HH18 pKa = 6.92ILSLADD24 pKa = 3.29IEE26 pKa = 4.36EE27 pKa = 4.16EE28 pKa = 4.58QMIQSVDD35 pKa = 3.17RR36 pKa = 11.84TAVTGASYY44 pKa = 7.83FTSVDD49 pKa = 3.17QSSVHH54 pKa = 4.42TAEE57 pKa = 4.41VGSHH61 pKa = 4.06QVEE64 pKa = 4.31PLRR67 pKa = 11.84TSVDD71 pKa = 3.18KK72 pKa = 11.07PGSKK76 pKa = 8.56KK77 pKa = 8.1TQGEE81 pKa = 4.49KK82 pKa = 10.68FFLIHH87 pKa = 6.17SADD90 pKa = 3.33WLTTHH95 pKa = 7.47ALFHH99 pKa = 6.33EE100 pKa = 4.75VAKK103 pKa = 10.89LDD105 pKa = 4.08VVKK108 pKa = 10.69LLYY111 pKa = 10.5NEE113 pKa = 3.96QFAVQGLLRR122 pKa = 11.84YY123 pKa = 7.97HH124 pKa = 6.65TYY126 pKa = 11.0ARR128 pKa = 11.84FGIEE132 pKa = 3.48IQVQINPTPFQQGGLICAMVPGDD155 pKa = 3.54QSYY158 pKa = 11.41GSIASLTVYY167 pKa = 10.23PHH169 pKa = 7.13GLLNCNINNVVRR181 pKa = 11.84IKK183 pKa = 11.15VPFIYY188 pKa = 10.17TRR190 pKa = 11.84GAYY193 pKa = 9.37HH194 pKa = 6.91FKK196 pKa = 10.64DD197 pKa = 3.09PQYY200 pKa = 10.4PVWEE204 pKa = 3.91LTIRR208 pKa = 11.84VWSEE212 pKa = 3.37LNIGTGTSAYY222 pKa = 9.47TSLNVLARR230 pKa = 11.84FTDD233 pKa = 4.19LEE235 pKa = 4.31LHH237 pKa = 6.28GLTPLSTQMMRR248 pKa = 11.84NEE250 pKa = 4.03FRR252 pKa = 11.84VSTTEE257 pKa = 3.83NVVNLSNYY265 pKa = 8.88EE266 pKa = 3.81DD267 pKa = 3.93ARR269 pKa = 11.84AKK271 pKa = 10.21MSFALDD277 pKa = 3.51QEE279 pKa = 4.65DD280 pKa = 3.94WKK282 pKa = 11.24SDD284 pKa = 3.39PSQGGGIKK292 pKa = 8.51ITHH295 pKa = 5.72FTTWTSIPTLAAQFPFNASDD315 pKa = 4.41SVGQQIKK322 pKa = 10.03VIPVDD327 pKa = 3.6PYY329 pKa = 10.38FFQMTNTNPDD339 pKa = 3.47QKK341 pKa = 10.73CITALASICQMFCFWRR357 pKa = 11.84GDD359 pKa = 3.61LVFDD363 pKa = 4.06FQVFPTKK370 pKa = 10.24YY371 pKa = 9.54HH372 pKa = 5.82SGRR375 pKa = 11.84LLFCFVPGNEE385 pKa = 4.86LIDD388 pKa = 3.66VSGITLKK395 pKa = 10.66QATTAPCAVMDD406 pKa = 3.6ITGVQSTLRR415 pKa = 11.84FRR417 pKa = 11.84VPWISDD423 pKa = 2.97TPYY426 pKa = 10.39RR427 pKa = 11.84VNRR430 pKa = 11.84YY431 pKa = 6.49TKK433 pKa = 9.86SAHH436 pKa = 5.76QKK438 pKa = 10.74GEE440 pKa = 3.7YY441 pKa = 8.22TAIGKK446 pKa = 9.42LIVYY450 pKa = 8.22CYY452 pKa = 10.9NRR454 pKa = 11.84LTSPSNVASHH464 pKa = 5.77VRR466 pKa = 11.84VNVYY470 pKa = 10.22LSAINLEE477 pKa = 4.58CFAPLYY483 pKa = 10.49HH484 pKa = 7.66AMDD487 pKa = 3.5VTTQVGDD494 pKa = 3.63DD495 pKa = 3.49SGGFSTTVSTEE506 pKa = 3.7QNVPDD511 pKa = 4.31PQVGITTMKK520 pKa = 10.41DD521 pKa = 3.21LKK523 pKa = 11.11GKK525 pKa = 10.24ANRR528 pKa = 11.84GKK530 pKa = 9.4MDD532 pKa = 3.15VSGVQAPVGAITTIEE547 pKa = 4.25DD548 pKa = 3.35PVLAKK553 pKa = 10.15KK554 pKa = 10.74VPEE557 pKa = 4.28TFPEE561 pKa = 4.44LKK563 pKa = 10.02PGEE566 pKa = 4.25SRR568 pKa = 11.84HH569 pKa = 5.81TSDD572 pKa = 4.56HH573 pKa = 5.09MSIYY577 pKa = 10.64KK578 pKa = 10.23FMGRR582 pKa = 11.84SHH584 pKa = 7.38FLCTFTFNSNNKK596 pKa = 9.48EE597 pKa = 3.81YY598 pKa = 9.95TFPITLSSTSNPPHH612 pKa = 6.59GLPSTLRR619 pKa = 11.84WFFNLFQLYY628 pKa = 10.0RR629 pKa = 11.84GPLDD633 pKa = 3.25LTIIITGATDD643 pKa = 3.26VDD645 pKa = 3.6GMAWFTPVGLAVDD658 pKa = 4.26TPWVEE663 pKa = 4.14KK664 pKa = 10.65EE665 pKa = 3.95SALSIDD671 pKa = 3.78YY672 pKa = 7.9KK673 pKa = 9.97TALGAVRR680 pKa = 11.84FNTRR684 pKa = 11.84RR685 pKa = 11.84TGNIQIRR692 pKa = 11.84LPWYY696 pKa = 8.11SYY698 pKa = 11.06LYY700 pKa = 10.3AVSGALDD707 pKa = 3.65GLGDD711 pKa = 3.81KK712 pKa = 10.25TDD714 pKa = 3.47STFGLVSIQIANYY727 pKa = 8.73NHH729 pKa = 6.55SDD731 pKa = 3.43EE732 pKa = 4.56YY733 pKa = 11.63LSFSCYY739 pKa = 10.5LSVTEE744 pKa = 3.89QSEE747 pKa = 5.61FYY749 pKa = 10.61FPRR752 pKa = 11.84APLNSNAMLSTEE764 pKa = 3.91SMMSRR769 pKa = 11.84IAAGDD774 pKa = 3.91LEE776 pKa = 4.88SSVDD780 pKa = 3.72DD781 pKa = 4.29PRR783 pKa = 11.84SEE785 pKa = 3.69EE786 pKa = 3.95DD787 pKa = 3.65KK788 pKa = 10.94RR789 pKa = 11.84FEE791 pKa = 4.19SHH793 pKa = 6.18IEE795 pKa = 3.56CRR797 pKa = 11.84KK798 pKa = 9.11PYY800 pKa = 10.24KK801 pKa = 9.82EE802 pKa = 4.21LRR804 pKa = 11.84LEE806 pKa = 4.13VGKK809 pKa = 10.23QRR811 pKa = 11.84LKK813 pKa = 10.51YY814 pKa = 10.03AQEE817 pKa = 3.9EE818 pKa = 4.43LSNEE822 pKa = 4.07VLPPPRR828 pKa = 11.84KK829 pKa = 9.0MKK831 pKa = 10.78GLFSQAKK838 pKa = 8.36ISLFYY843 pKa = 10.6TEE845 pKa = 4.39EE846 pKa = 4.3HH847 pKa = 6.99EE848 pKa = 4.37IMKK851 pKa = 9.4FSWRR855 pKa = 11.84GVTADD860 pKa = 3.19TRR862 pKa = 11.84ALRR865 pKa = 11.84RR866 pKa = 11.84FGFSLAAGRR875 pKa = 11.84SVWTLEE881 pKa = 3.44MDD883 pKa = 3.62AGVLTGRR890 pKa = 11.84LIRR893 pKa = 11.84LNDD896 pKa = 3.78EE897 pKa = 4.14KK898 pKa = 9.81WTEE901 pKa = 3.96MKK903 pKa = 10.35DD904 pKa = 3.58DD905 pKa = 5.08KK906 pKa = 10.93IVSLIEE912 pKa = 3.92KK913 pKa = 7.79FTSNKK918 pKa = 9.28YY919 pKa = 6.88WSKK922 pKa = 11.09VNFPHH927 pKa = 7.25GMLDD931 pKa = 3.83LEE933 pKa = 4.68EE934 pKa = 4.31IAANSKK940 pKa = 10.42DD941 pKa = 3.87FPNMSEE947 pKa = 3.89TDD949 pKa = 3.67LCFLLHH955 pKa = 6.48WLNPKK960 pKa = 9.86KK961 pKa = 10.48INLADD966 pKa = 3.9RR967 pKa = 11.84MLGLSGVQEE976 pKa = 3.98IKK978 pKa = 10.46EE979 pKa = 4.0QGVGLIAEE987 pKa = 4.75CRR989 pKa = 11.84TFLDD993 pKa = 4.81SIAGTLKK1000 pKa = 10.61SMMFGFHH1007 pKa = 6.6HH1008 pKa = 6.62SVTVEE1013 pKa = 4.11IINTVLCFVKK1023 pKa = 10.52SGILLYY1029 pKa = 10.66VIQQLNQDD1037 pKa = 3.81EE1038 pKa = 4.49HH1039 pKa = 7.24SHH1041 pKa = 6.79IIGLLRR1047 pKa = 11.84VMNYY1051 pKa = 10.7ADD1053 pKa = 4.05IGCSVISCGKK1063 pKa = 9.71VFSKK1067 pKa = 10.4MLEE1070 pKa = 4.4TVFNWQMDD1078 pKa = 3.75SRR1080 pKa = 11.84MMEE1083 pKa = 3.98LRR1085 pKa = 11.84TQSFSNWLRR1094 pKa = 11.84DD1095 pKa = 3.15ICSGITIFKK1104 pKa = 9.74NFKK1107 pKa = 10.12DD1108 pKa = 4.0AIYY1111 pKa = 10.26WLYY1114 pKa = 10.87TKK1116 pKa = 10.77LKK1118 pKa = 10.44DD1119 pKa = 4.14FYY1121 pKa = 10.87EE1122 pKa = 4.21VNYY1125 pKa = 10.3GKK1127 pKa = 10.55KK1128 pKa = 9.81KK1129 pKa = 10.75DD1130 pKa = 3.54ILNILKK1136 pKa = 10.43DD1137 pKa = 3.72NQQKK1141 pKa = 9.65IEE1143 pKa = 4.04KK1144 pKa = 9.51AIEE1147 pKa = 3.86EE1148 pKa = 4.05ADD1150 pKa = 3.9EE1151 pKa = 4.44FCILQIQDD1159 pKa = 3.32VEE1161 pKa = 4.79KK1162 pKa = 10.86FEE1164 pKa = 4.51QYY1166 pKa = 10.51QKK1168 pKa = 11.31GVDD1171 pKa = 4.74LIQKK1175 pKa = 9.55LRR1177 pKa = 11.84TVHH1180 pKa = 6.8SMAQVDD1186 pKa = 4.3PNLMVHH1192 pKa = 6.81LSPLRR1197 pKa = 11.84DD1198 pKa = 3.95CIARR1202 pKa = 11.84VHH1204 pKa = 6.07QKK1206 pKa = 10.52LKK1208 pKa = 10.87NLGSINQAMVTRR1220 pKa = 11.84CEE1222 pKa = 3.84PVVCYY1227 pKa = 10.21LYY1229 pKa = 10.94GKK1231 pKa = 10.18RR1232 pKa = 11.84GGGKK1236 pKa = 9.51SLTSIALATKK1246 pKa = 8.82ICKK1249 pKa = 10.0HH1250 pKa = 5.98YY1251 pKa = 10.75GVEE1254 pKa = 4.1PEE1256 pKa = 4.04KK1257 pKa = 11.11NIYY1260 pKa = 7.41TKK1262 pKa = 10.52PVASDD1267 pKa = 3.2YY1268 pKa = 10.42WDD1270 pKa = 4.48GYY1272 pKa = 10.74SGQLVCIIDD1281 pKa = 5.5DD1282 pKa = 3.62IGQNTTDD1289 pKa = 4.05EE1290 pKa = 4.46DD1291 pKa = 3.64WSDD1294 pKa = 3.53FCQLVSGCPMRR1305 pKa = 11.84LNMASLEE1312 pKa = 4.23EE1313 pKa = 4.19KK1314 pKa = 10.26GRR1316 pKa = 11.84HH1317 pKa = 4.88FSSPFIIATSNWSNPSPKK1335 pKa = 9.3TVYY1338 pKa = 10.25VKK1340 pKa = 10.45EE1341 pKa = 4.52AIDD1344 pKa = 3.44RR1345 pKa = 11.84RR1346 pKa = 11.84LHH1348 pKa = 5.88FKK1350 pKa = 11.24VEE1352 pKa = 4.06VKK1354 pKa = 9.93PASFFKK1360 pKa = 10.91NPHH1363 pKa = 5.68NDD1365 pKa = 3.15MLNVNLAKK1373 pKa = 10.36TNDD1376 pKa = 3.93AIKK1379 pKa = 10.96DD1380 pKa = 3.69MSCVDD1385 pKa = 5.88LIMDD1389 pKa = 3.94GHH1391 pKa = 6.11NVSLMDD1397 pKa = 4.39LLSSLVMTVEE1407 pKa = 3.7IRR1409 pKa = 11.84KK1410 pKa = 9.41QNMTEE1415 pKa = 4.95FMEE1418 pKa = 4.63LWSQGISDD1426 pKa = 5.43DD1427 pKa = 4.92DD1428 pKa = 4.08NDD1430 pKa = 3.95SAVAEE1435 pKa = 4.63FFQSFPSGEE1444 pKa = 3.99PSNSKK1449 pKa = 10.64LSGFFQSVTNHH1460 pKa = 4.72KK1461 pKa = 8.8WVAVGAAVGILGVLVGGWFVYY1482 pKa = 10.39KK1483 pKa = 10.44HH1484 pKa = 6.05FSRR1487 pKa = 11.84KK1488 pKa = 8.57EE1489 pKa = 3.87EE1490 pKa = 3.92EE1491 pKa = 4.74PIPAEE1496 pKa = 4.07GVYY1499 pKa = 10.54HH1500 pKa = 7.09GVTKK1504 pKa = 10.25PKK1506 pKa = 10.51QVIKK1510 pKa = 10.88LDD1512 pKa = 3.9ADD1514 pKa = 3.68PVEE1517 pKa = 4.51SQSTLEE1523 pKa = 3.79IAGLVRR1529 pKa = 11.84KK1530 pKa = 9.84NLVQFGVGEE1539 pKa = 4.1KK1540 pKa = 9.74NGCVRR1545 pKa = 11.84WVMNALGVKK1554 pKa = 9.97DD1555 pKa = 4.4DD1556 pKa = 3.64WLLVPSHH1563 pKa = 6.88AYY1565 pKa = 9.71KK1566 pKa = 10.63FEE1568 pKa = 4.44KK1569 pKa = 9.99DD1570 pKa = 3.45YY1571 pKa = 11.65EE1572 pKa = 4.18MMEE1575 pKa = 4.53FYY1577 pKa = 10.69FNRR1580 pKa = 11.84GGTYY1584 pKa = 10.33YY1585 pKa = 10.58SISAGNVVIQSLDD1598 pKa = 3.22VGFQDD1603 pKa = 3.47VVLMKK1608 pKa = 10.71VPTIPKK1614 pKa = 9.58FRR1616 pKa = 11.84DD1617 pKa = 3.0ITQHH1621 pKa = 6.46FIKK1624 pKa = 10.64KK1625 pKa = 9.89GDD1627 pKa = 3.48VPRR1630 pKa = 11.84ALNRR1634 pKa = 11.84LATLVTTVNGTPMLISEE1651 pKa = 5.25GPLKK1655 pKa = 10.26MEE1657 pKa = 4.43EE1658 pKa = 4.05KK1659 pKa = 9.81ATYY1662 pKa = 7.95VHH1664 pKa = 6.78KK1665 pKa = 11.07KK1666 pKa = 10.44NDD1668 pKa = 3.47GTTVDD1673 pKa = 4.14LTVDD1677 pKa = 3.38QAWRR1681 pKa = 11.84GKK1683 pKa = 10.89GEE1685 pKa = 4.48GLPGMCGGALVSSNQSIQNAILGIHH1710 pKa = 5.3VAGGNSILVAKK1721 pKa = 10.41LVTQEE1726 pKa = 3.76MFQNIDD1732 pKa = 3.41KK1733 pKa = 10.51KK1734 pKa = 10.82IEE1736 pKa = 3.87SQRR1739 pKa = 11.84IMKK1742 pKa = 9.93VEE1744 pKa = 4.37FTQCSMNVVSKK1755 pKa = 9.45TLFRR1759 pKa = 11.84KK1760 pKa = 10.04SPIYY1764 pKa = 10.35HH1765 pKa = 6.98HH1766 pKa = 7.17IDD1768 pKa = 2.63KK1769 pKa = 11.0TMINFPAAMPFSKK1782 pKa = 11.17AEE1784 pKa = 4.0IDD1786 pKa = 3.63PMAVMLSKK1794 pKa = 10.95YY1795 pKa = 9.9SLPIVEE1801 pKa = 4.68EE1802 pKa = 4.27PEE1804 pKa = 4.19DD1805 pKa = 3.76YY1806 pKa = 10.96KK1807 pKa = 11.05EE1808 pKa = 5.06ASIFYY1813 pKa = 9.6QNKK1816 pKa = 9.36IVGKK1820 pKa = 7.17TQLVDD1825 pKa = 4.14DD1826 pKa = 4.9FLDD1829 pKa = 4.4LDD1831 pKa = 3.97MAITGAPGIDD1841 pKa = 4.57AINMDD1846 pKa = 4.39SSPGFPYY1853 pKa = 10.56VQEE1856 pKa = 4.41KK1857 pKa = 8.32LTKK1860 pKa = 9.76RR1861 pKa = 11.84DD1862 pKa = 4.55LIWLDD1867 pKa = 3.71EE1868 pKa = 4.36NGLLLGVHH1876 pKa = 6.56PRR1878 pKa = 11.84LAQRR1882 pKa = 11.84ILFNTVMMEE1891 pKa = 3.9NCSDD1895 pKa = 4.05LDD1897 pKa = 4.05VVFTTCPKK1905 pKa = 10.94DD1906 pKa = 3.44EE1907 pKa = 4.6LRR1909 pKa = 11.84PLEE1912 pKa = 4.55KK1913 pKa = 10.58VLEE1916 pKa = 4.47SKK1918 pKa = 9.24TRR1920 pKa = 11.84AIDD1923 pKa = 3.68ACPLDD1928 pKa = 4.13YY1929 pKa = 11.11SILCRR1934 pKa = 11.84MYY1936 pKa = 8.4WGPAISYY1943 pKa = 7.87FHH1945 pKa = 7.06LNPGFHH1951 pKa = 6.4TGVAIGIDD1959 pKa = 4.14PDD1961 pKa = 3.96RR1962 pKa = 11.84QWDD1965 pKa = 3.85EE1966 pKa = 4.09LFKK1969 pKa = 10.92TMIRR1973 pKa = 11.84FGDD1976 pKa = 3.43VGLDD1980 pKa = 3.39LDD1982 pKa = 5.24FSAFDD1987 pKa = 3.68ASLSPFMIRR1996 pKa = 11.84EE1997 pKa = 4.08AGRR2000 pKa = 11.84IMSEE2004 pKa = 3.88LSGTPSHH2011 pKa = 7.41FGTALINTIIYY2022 pKa = 10.05SKK2024 pKa = 10.68HH2025 pKa = 6.0LLYY2028 pKa = 10.71NCCYY2032 pKa = 8.98HH2033 pKa = 6.37VCGSMPSGSPCTALLNSIINNVNLYY2058 pKa = 10.36YY2059 pKa = 10.73VFSKK2063 pKa = 10.62IFGKK2067 pKa = 10.64SPVFFCQALKK2077 pKa = 10.31ILCYY2081 pKa = 10.51GDD2083 pKa = 4.66DD2084 pKa = 3.66VLIVFSRR2091 pKa = 11.84DD2092 pKa = 3.43VQIDD2096 pKa = 3.57NLDD2099 pKa = 4.42LIGQKK2104 pKa = 9.82IVDD2107 pKa = 3.97EE2108 pKa = 4.63FKK2110 pKa = 11.03KK2111 pKa = 10.82LGMTATSADD2120 pKa = 3.6KK2121 pKa = 10.76NVPQLKK2127 pKa = 9.45PVSEE2131 pKa = 4.13LTFLKK2136 pKa = 10.52RR2137 pKa = 11.84SFNLVEE2143 pKa = 4.08DD2144 pKa = 5.08RR2145 pKa = 11.84IRR2147 pKa = 11.84PAISEE2152 pKa = 4.08KK2153 pKa = 10.43TIWSLIAWQRR2163 pKa = 11.84SNAEE2167 pKa = 3.8FEE2169 pKa = 4.51QNLEE2173 pKa = 3.9NAQWFAFMHH2182 pKa = 6.63GYY2184 pKa = 10.06EE2185 pKa = 5.06FYY2187 pKa = 10.77QKK2189 pKa = 10.25FYY2191 pKa = 11.28YY2192 pKa = 10.23FVQSCLEE2199 pKa = 3.98KK2200 pKa = 11.07EE2201 pKa = 4.19MIEE2204 pKa = 4.12YY2205 pKa = 10.42RR2206 pKa = 11.84LKK2208 pKa = 11.06SYY2210 pKa = 10.5DD2211 pKa = 2.63WWRR2214 pKa = 11.84MRR2216 pKa = 11.84FYY2218 pKa = 10.36DD2219 pKa = 3.66QCFICDD2225 pKa = 3.94LSS2227 pKa = 3.54
MM1 pKa = 7.18NMSRR5 pKa = 11.84QGIFQTVGSGLDD17 pKa = 4.01HH18 pKa = 6.92ILSLADD24 pKa = 3.29IEE26 pKa = 4.36EE27 pKa = 4.16EE28 pKa = 4.58QMIQSVDD35 pKa = 3.17RR36 pKa = 11.84TAVTGASYY44 pKa = 7.83FTSVDD49 pKa = 3.17QSSVHH54 pKa = 4.42TAEE57 pKa = 4.41VGSHH61 pKa = 4.06QVEE64 pKa = 4.31PLRR67 pKa = 11.84TSVDD71 pKa = 3.18KK72 pKa = 11.07PGSKK76 pKa = 8.56KK77 pKa = 8.1TQGEE81 pKa = 4.49KK82 pKa = 10.68FFLIHH87 pKa = 6.17SADD90 pKa = 3.33WLTTHH95 pKa = 7.47ALFHH99 pKa = 6.33EE100 pKa = 4.75VAKK103 pKa = 10.89LDD105 pKa = 4.08VVKK108 pKa = 10.69LLYY111 pKa = 10.5NEE113 pKa = 3.96QFAVQGLLRR122 pKa = 11.84YY123 pKa = 7.97HH124 pKa = 6.65TYY126 pKa = 11.0ARR128 pKa = 11.84FGIEE132 pKa = 3.48IQVQINPTPFQQGGLICAMVPGDD155 pKa = 3.54QSYY158 pKa = 11.41GSIASLTVYY167 pKa = 10.23PHH169 pKa = 7.13GLLNCNINNVVRR181 pKa = 11.84IKK183 pKa = 11.15VPFIYY188 pKa = 10.17TRR190 pKa = 11.84GAYY193 pKa = 9.37HH194 pKa = 6.91FKK196 pKa = 10.64DD197 pKa = 3.09PQYY200 pKa = 10.4PVWEE204 pKa = 3.91LTIRR208 pKa = 11.84VWSEE212 pKa = 3.37LNIGTGTSAYY222 pKa = 9.47TSLNVLARR230 pKa = 11.84FTDD233 pKa = 4.19LEE235 pKa = 4.31LHH237 pKa = 6.28GLTPLSTQMMRR248 pKa = 11.84NEE250 pKa = 4.03FRR252 pKa = 11.84VSTTEE257 pKa = 3.83NVVNLSNYY265 pKa = 8.88EE266 pKa = 3.81DD267 pKa = 3.93ARR269 pKa = 11.84AKK271 pKa = 10.21MSFALDD277 pKa = 3.51QEE279 pKa = 4.65DD280 pKa = 3.94WKK282 pKa = 11.24SDD284 pKa = 3.39PSQGGGIKK292 pKa = 8.51ITHH295 pKa = 5.72FTTWTSIPTLAAQFPFNASDD315 pKa = 4.41SVGQQIKK322 pKa = 10.03VIPVDD327 pKa = 3.6PYY329 pKa = 10.38FFQMTNTNPDD339 pKa = 3.47QKK341 pKa = 10.73CITALASICQMFCFWRR357 pKa = 11.84GDD359 pKa = 3.61LVFDD363 pKa = 4.06FQVFPTKK370 pKa = 10.24YY371 pKa = 9.54HH372 pKa = 5.82SGRR375 pKa = 11.84LLFCFVPGNEE385 pKa = 4.86LIDD388 pKa = 3.66VSGITLKK395 pKa = 10.66QATTAPCAVMDD406 pKa = 3.6ITGVQSTLRR415 pKa = 11.84FRR417 pKa = 11.84VPWISDD423 pKa = 2.97TPYY426 pKa = 10.39RR427 pKa = 11.84VNRR430 pKa = 11.84YY431 pKa = 6.49TKK433 pKa = 9.86SAHH436 pKa = 5.76QKK438 pKa = 10.74GEE440 pKa = 3.7YY441 pKa = 8.22TAIGKK446 pKa = 9.42LIVYY450 pKa = 8.22CYY452 pKa = 10.9NRR454 pKa = 11.84LTSPSNVASHH464 pKa = 5.77VRR466 pKa = 11.84VNVYY470 pKa = 10.22LSAINLEE477 pKa = 4.58CFAPLYY483 pKa = 10.49HH484 pKa = 7.66AMDD487 pKa = 3.5VTTQVGDD494 pKa = 3.63DD495 pKa = 3.49SGGFSTTVSTEE506 pKa = 3.7QNVPDD511 pKa = 4.31PQVGITTMKK520 pKa = 10.41DD521 pKa = 3.21LKK523 pKa = 11.11GKK525 pKa = 10.24ANRR528 pKa = 11.84GKK530 pKa = 9.4MDD532 pKa = 3.15VSGVQAPVGAITTIEE547 pKa = 4.25DD548 pKa = 3.35PVLAKK553 pKa = 10.15KK554 pKa = 10.74VPEE557 pKa = 4.28TFPEE561 pKa = 4.44LKK563 pKa = 10.02PGEE566 pKa = 4.25SRR568 pKa = 11.84HH569 pKa = 5.81TSDD572 pKa = 4.56HH573 pKa = 5.09MSIYY577 pKa = 10.64KK578 pKa = 10.23FMGRR582 pKa = 11.84SHH584 pKa = 7.38FLCTFTFNSNNKK596 pKa = 9.48EE597 pKa = 3.81YY598 pKa = 9.95TFPITLSSTSNPPHH612 pKa = 6.59GLPSTLRR619 pKa = 11.84WFFNLFQLYY628 pKa = 10.0RR629 pKa = 11.84GPLDD633 pKa = 3.25LTIIITGATDD643 pKa = 3.26VDD645 pKa = 3.6GMAWFTPVGLAVDD658 pKa = 4.26TPWVEE663 pKa = 4.14KK664 pKa = 10.65EE665 pKa = 3.95SALSIDD671 pKa = 3.78YY672 pKa = 7.9KK673 pKa = 9.97TALGAVRR680 pKa = 11.84FNTRR684 pKa = 11.84RR685 pKa = 11.84TGNIQIRR692 pKa = 11.84LPWYY696 pKa = 8.11SYY698 pKa = 11.06LYY700 pKa = 10.3AVSGALDD707 pKa = 3.65GLGDD711 pKa = 3.81KK712 pKa = 10.25TDD714 pKa = 3.47STFGLVSIQIANYY727 pKa = 8.73NHH729 pKa = 6.55SDD731 pKa = 3.43EE732 pKa = 4.56YY733 pKa = 11.63LSFSCYY739 pKa = 10.5LSVTEE744 pKa = 3.89QSEE747 pKa = 5.61FYY749 pKa = 10.61FPRR752 pKa = 11.84APLNSNAMLSTEE764 pKa = 3.91SMMSRR769 pKa = 11.84IAAGDD774 pKa = 3.91LEE776 pKa = 4.88SSVDD780 pKa = 3.72DD781 pKa = 4.29PRR783 pKa = 11.84SEE785 pKa = 3.69EE786 pKa = 3.95DD787 pKa = 3.65KK788 pKa = 10.94RR789 pKa = 11.84FEE791 pKa = 4.19SHH793 pKa = 6.18IEE795 pKa = 3.56CRR797 pKa = 11.84KK798 pKa = 9.11PYY800 pKa = 10.24KK801 pKa = 9.82EE802 pKa = 4.21LRR804 pKa = 11.84LEE806 pKa = 4.13VGKK809 pKa = 10.23QRR811 pKa = 11.84LKK813 pKa = 10.51YY814 pKa = 10.03AQEE817 pKa = 3.9EE818 pKa = 4.43LSNEE822 pKa = 4.07VLPPPRR828 pKa = 11.84KK829 pKa = 9.0MKK831 pKa = 10.78GLFSQAKK838 pKa = 8.36ISLFYY843 pKa = 10.6TEE845 pKa = 4.39EE846 pKa = 4.3HH847 pKa = 6.99EE848 pKa = 4.37IMKK851 pKa = 9.4FSWRR855 pKa = 11.84GVTADD860 pKa = 3.19TRR862 pKa = 11.84ALRR865 pKa = 11.84RR866 pKa = 11.84FGFSLAAGRR875 pKa = 11.84SVWTLEE881 pKa = 3.44MDD883 pKa = 3.62AGVLTGRR890 pKa = 11.84LIRR893 pKa = 11.84LNDD896 pKa = 3.78EE897 pKa = 4.14KK898 pKa = 9.81WTEE901 pKa = 3.96MKK903 pKa = 10.35DD904 pKa = 3.58DD905 pKa = 5.08KK906 pKa = 10.93IVSLIEE912 pKa = 3.92KK913 pKa = 7.79FTSNKK918 pKa = 9.28YY919 pKa = 6.88WSKK922 pKa = 11.09VNFPHH927 pKa = 7.25GMLDD931 pKa = 3.83LEE933 pKa = 4.68EE934 pKa = 4.31IAANSKK940 pKa = 10.42DD941 pKa = 3.87FPNMSEE947 pKa = 3.89TDD949 pKa = 3.67LCFLLHH955 pKa = 6.48WLNPKK960 pKa = 9.86KK961 pKa = 10.48INLADD966 pKa = 3.9RR967 pKa = 11.84MLGLSGVQEE976 pKa = 3.98IKK978 pKa = 10.46EE979 pKa = 4.0QGVGLIAEE987 pKa = 4.75CRR989 pKa = 11.84TFLDD993 pKa = 4.81SIAGTLKK1000 pKa = 10.61SMMFGFHH1007 pKa = 6.6HH1008 pKa = 6.62SVTVEE1013 pKa = 4.11IINTVLCFVKK1023 pKa = 10.52SGILLYY1029 pKa = 10.66VIQQLNQDD1037 pKa = 3.81EE1038 pKa = 4.49HH1039 pKa = 7.24SHH1041 pKa = 6.79IIGLLRR1047 pKa = 11.84VMNYY1051 pKa = 10.7ADD1053 pKa = 4.05IGCSVISCGKK1063 pKa = 9.71VFSKK1067 pKa = 10.4MLEE1070 pKa = 4.4TVFNWQMDD1078 pKa = 3.75SRR1080 pKa = 11.84MMEE1083 pKa = 3.98LRR1085 pKa = 11.84TQSFSNWLRR1094 pKa = 11.84DD1095 pKa = 3.15ICSGITIFKK1104 pKa = 9.74NFKK1107 pKa = 10.12DD1108 pKa = 4.0AIYY1111 pKa = 10.26WLYY1114 pKa = 10.87TKK1116 pKa = 10.77LKK1118 pKa = 10.44DD1119 pKa = 4.14FYY1121 pKa = 10.87EE1122 pKa = 4.21VNYY1125 pKa = 10.3GKK1127 pKa = 10.55KK1128 pKa = 9.81KK1129 pKa = 10.75DD1130 pKa = 3.54ILNILKK1136 pKa = 10.43DD1137 pKa = 3.72NQQKK1141 pKa = 9.65IEE1143 pKa = 4.04KK1144 pKa = 9.51AIEE1147 pKa = 3.86EE1148 pKa = 4.05ADD1150 pKa = 3.9EE1151 pKa = 4.44FCILQIQDD1159 pKa = 3.32VEE1161 pKa = 4.79KK1162 pKa = 10.86FEE1164 pKa = 4.51QYY1166 pKa = 10.51QKK1168 pKa = 11.31GVDD1171 pKa = 4.74LIQKK1175 pKa = 9.55LRR1177 pKa = 11.84TVHH1180 pKa = 6.8SMAQVDD1186 pKa = 4.3PNLMVHH1192 pKa = 6.81LSPLRR1197 pKa = 11.84DD1198 pKa = 3.95CIARR1202 pKa = 11.84VHH1204 pKa = 6.07QKK1206 pKa = 10.52LKK1208 pKa = 10.87NLGSINQAMVTRR1220 pKa = 11.84CEE1222 pKa = 3.84PVVCYY1227 pKa = 10.21LYY1229 pKa = 10.94GKK1231 pKa = 10.18RR1232 pKa = 11.84GGGKK1236 pKa = 9.51SLTSIALATKK1246 pKa = 8.82ICKK1249 pKa = 10.0HH1250 pKa = 5.98YY1251 pKa = 10.75GVEE1254 pKa = 4.1PEE1256 pKa = 4.04KK1257 pKa = 11.11NIYY1260 pKa = 7.41TKK1262 pKa = 10.52PVASDD1267 pKa = 3.2YY1268 pKa = 10.42WDD1270 pKa = 4.48GYY1272 pKa = 10.74SGQLVCIIDD1281 pKa = 5.5DD1282 pKa = 3.62IGQNTTDD1289 pKa = 4.05EE1290 pKa = 4.46DD1291 pKa = 3.64WSDD1294 pKa = 3.53FCQLVSGCPMRR1305 pKa = 11.84LNMASLEE1312 pKa = 4.23EE1313 pKa = 4.19KK1314 pKa = 10.26GRR1316 pKa = 11.84HH1317 pKa = 4.88FSSPFIIATSNWSNPSPKK1335 pKa = 9.3TVYY1338 pKa = 10.25VKK1340 pKa = 10.45EE1341 pKa = 4.52AIDD1344 pKa = 3.44RR1345 pKa = 11.84RR1346 pKa = 11.84LHH1348 pKa = 5.88FKK1350 pKa = 11.24VEE1352 pKa = 4.06VKK1354 pKa = 9.93PASFFKK1360 pKa = 10.91NPHH1363 pKa = 5.68NDD1365 pKa = 3.15MLNVNLAKK1373 pKa = 10.36TNDD1376 pKa = 3.93AIKK1379 pKa = 10.96DD1380 pKa = 3.69MSCVDD1385 pKa = 5.88LIMDD1389 pKa = 3.94GHH1391 pKa = 6.11NVSLMDD1397 pKa = 4.39LLSSLVMTVEE1407 pKa = 3.7IRR1409 pKa = 11.84KK1410 pKa = 9.41QNMTEE1415 pKa = 4.95FMEE1418 pKa = 4.63LWSQGISDD1426 pKa = 5.43DD1427 pKa = 4.92DD1428 pKa = 4.08NDD1430 pKa = 3.95SAVAEE1435 pKa = 4.63FFQSFPSGEE1444 pKa = 3.99PSNSKK1449 pKa = 10.64LSGFFQSVTNHH1460 pKa = 4.72KK1461 pKa = 8.8WVAVGAAVGILGVLVGGWFVYY1482 pKa = 10.39KK1483 pKa = 10.44HH1484 pKa = 6.05FSRR1487 pKa = 11.84KK1488 pKa = 8.57EE1489 pKa = 3.87EE1490 pKa = 3.92EE1491 pKa = 4.74PIPAEE1496 pKa = 4.07GVYY1499 pKa = 10.54HH1500 pKa = 7.09GVTKK1504 pKa = 10.25PKK1506 pKa = 10.51QVIKK1510 pKa = 10.88LDD1512 pKa = 3.9ADD1514 pKa = 3.68PVEE1517 pKa = 4.51SQSTLEE1523 pKa = 3.79IAGLVRR1529 pKa = 11.84KK1530 pKa = 9.84NLVQFGVGEE1539 pKa = 4.1KK1540 pKa = 9.74NGCVRR1545 pKa = 11.84WVMNALGVKK1554 pKa = 9.97DD1555 pKa = 4.4DD1556 pKa = 3.64WLLVPSHH1563 pKa = 6.88AYY1565 pKa = 9.71KK1566 pKa = 10.63FEE1568 pKa = 4.44KK1569 pKa = 9.99DD1570 pKa = 3.45YY1571 pKa = 11.65EE1572 pKa = 4.18MMEE1575 pKa = 4.53FYY1577 pKa = 10.69FNRR1580 pKa = 11.84GGTYY1584 pKa = 10.33YY1585 pKa = 10.58SISAGNVVIQSLDD1598 pKa = 3.22VGFQDD1603 pKa = 3.47VVLMKK1608 pKa = 10.71VPTIPKK1614 pKa = 9.58FRR1616 pKa = 11.84DD1617 pKa = 3.0ITQHH1621 pKa = 6.46FIKK1624 pKa = 10.64KK1625 pKa = 9.89GDD1627 pKa = 3.48VPRR1630 pKa = 11.84ALNRR1634 pKa = 11.84LATLVTTVNGTPMLISEE1651 pKa = 5.25GPLKK1655 pKa = 10.26MEE1657 pKa = 4.43EE1658 pKa = 4.05KK1659 pKa = 9.81ATYY1662 pKa = 7.95VHH1664 pKa = 6.78KK1665 pKa = 11.07KK1666 pKa = 10.44NDD1668 pKa = 3.47GTTVDD1673 pKa = 4.14LTVDD1677 pKa = 3.38QAWRR1681 pKa = 11.84GKK1683 pKa = 10.89GEE1685 pKa = 4.48GLPGMCGGALVSSNQSIQNAILGIHH1710 pKa = 5.3VAGGNSILVAKK1721 pKa = 10.41LVTQEE1726 pKa = 3.76MFQNIDD1732 pKa = 3.41KK1733 pKa = 10.51KK1734 pKa = 10.82IEE1736 pKa = 3.87SQRR1739 pKa = 11.84IMKK1742 pKa = 9.93VEE1744 pKa = 4.37FTQCSMNVVSKK1755 pKa = 9.45TLFRR1759 pKa = 11.84KK1760 pKa = 10.04SPIYY1764 pKa = 10.35HH1765 pKa = 6.98HH1766 pKa = 7.17IDD1768 pKa = 2.63KK1769 pKa = 11.0TMINFPAAMPFSKK1782 pKa = 11.17AEE1784 pKa = 4.0IDD1786 pKa = 3.63PMAVMLSKK1794 pKa = 10.95YY1795 pKa = 9.9SLPIVEE1801 pKa = 4.68EE1802 pKa = 4.27PEE1804 pKa = 4.19DD1805 pKa = 3.76YY1806 pKa = 10.96KK1807 pKa = 11.05EE1808 pKa = 5.06ASIFYY1813 pKa = 9.6QNKK1816 pKa = 9.36IVGKK1820 pKa = 7.17TQLVDD1825 pKa = 4.14DD1826 pKa = 4.9FLDD1829 pKa = 4.4LDD1831 pKa = 3.97MAITGAPGIDD1841 pKa = 4.57AINMDD1846 pKa = 4.39SSPGFPYY1853 pKa = 10.56VQEE1856 pKa = 4.41KK1857 pKa = 8.32LTKK1860 pKa = 9.76RR1861 pKa = 11.84DD1862 pKa = 4.55LIWLDD1867 pKa = 3.71EE1868 pKa = 4.36NGLLLGVHH1876 pKa = 6.56PRR1878 pKa = 11.84LAQRR1882 pKa = 11.84ILFNTVMMEE1891 pKa = 3.9NCSDD1895 pKa = 4.05LDD1897 pKa = 4.05VVFTTCPKK1905 pKa = 10.94DD1906 pKa = 3.44EE1907 pKa = 4.6LRR1909 pKa = 11.84PLEE1912 pKa = 4.55KK1913 pKa = 10.58VLEE1916 pKa = 4.47SKK1918 pKa = 9.24TRR1920 pKa = 11.84AIDD1923 pKa = 3.68ACPLDD1928 pKa = 4.13YY1929 pKa = 11.11SILCRR1934 pKa = 11.84MYY1936 pKa = 8.4WGPAISYY1943 pKa = 7.87FHH1945 pKa = 7.06LNPGFHH1951 pKa = 6.4TGVAIGIDD1959 pKa = 4.14PDD1961 pKa = 3.96RR1962 pKa = 11.84QWDD1965 pKa = 3.85EE1966 pKa = 4.09LFKK1969 pKa = 10.92TMIRR1973 pKa = 11.84FGDD1976 pKa = 3.43VGLDD1980 pKa = 3.39LDD1982 pKa = 5.24FSAFDD1987 pKa = 3.68ASLSPFMIRR1996 pKa = 11.84EE1997 pKa = 4.08AGRR2000 pKa = 11.84IMSEE2004 pKa = 3.88LSGTPSHH2011 pKa = 7.41FGTALINTIIYY2022 pKa = 10.05SKK2024 pKa = 10.68HH2025 pKa = 6.0LLYY2028 pKa = 10.71NCCYY2032 pKa = 8.98HH2033 pKa = 6.37VCGSMPSGSPCTALLNSIINNVNLYY2058 pKa = 10.36YY2059 pKa = 10.73VFSKK2063 pKa = 10.62IFGKK2067 pKa = 10.64SPVFFCQALKK2077 pKa = 10.31ILCYY2081 pKa = 10.51GDD2083 pKa = 4.66DD2084 pKa = 3.66VLIVFSRR2091 pKa = 11.84DD2092 pKa = 3.43VQIDD2096 pKa = 3.57NLDD2099 pKa = 4.42LIGQKK2104 pKa = 9.82IVDD2107 pKa = 3.97EE2108 pKa = 4.63FKK2110 pKa = 11.03KK2111 pKa = 10.82LGMTATSADD2120 pKa = 3.6KK2121 pKa = 10.76NVPQLKK2127 pKa = 9.45PVSEE2131 pKa = 4.13LTFLKK2136 pKa = 10.52RR2137 pKa = 11.84SFNLVEE2143 pKa = 4.08DD2144 pKa = 5.08RR2145 pKa = 11.84IRR2147 pKa = 11.84PAISEE2152 pKa = 4.08KK2153 pKa = 10.43TIWSLIAWQRR2163 pKa = 11.84SNAEE2167 pKa = 3.8FEE2169 pKa = 4.51QNLEE2173 pKa = 3.9NAQWFAFMHH2182 pKa = 6.63GYY2184 pKa = 10.06EE2185 pKa = 5.06FYY2187 pKa = 10.77QKK2189 pKa = 10.25FYY2191 pKa = 11.28YY2192 pKa = 10.23FVQSCLEE2199 pKa = 3.98KK2200 pKa = 11.07EE2201 pKa = 4.19MIEE2204 pKa = 4.12YY2205 pKa = 10.42RR2206 pKa = 11.84LKK2208 pKa = 11.06SYY2210 pKa = 10.5DD2211 pKa = 2.63WWRR2214 pKa = 11.84MRR2216 pKa = 11.84FYY2218 pKa = 10.36DD2219 pKa = 3.66QCFICDD2225 pKa = 3.94LSS2227 pKa = 3.54
Molecular weight: 251.51 kDa
Isoelectric point according different methods:
Peptides (in silico digests for buttom-up proteomics)
Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.| Try ESI |
 |
|---|
| ChTry ESI |
|
|---|
| ArgC ESI |
|
|---|
| LysN ESI |
|
|---|
| TryLysC ESI |
|
|---|
| Try MALDI |
|
|---|
| ChTry MALDI |
|
|---|
| ArgC MALDI |
|
|---|
| LysN MALDI |
|
|---|
| TryLysC MALDI |
|
|---|
| Try LTQ |
|
|---|
| ChTry LTQ |
|
|---|
| ArgC LTQ |
|
|---|
| LysN LTQ |
|
|---|
| TryLysC LTQ |
|
|---|
| Try MSlow |
|
|---|
| ChTry MSlow |
|
|---|
| ArgC MSlow |
|
|---|
| LysN MSlow |
|
|---|
| TryLysC MSlow |
|
|---|
| Try MShigh |
|
|---|
| ChTry MShigh |
|
|---|
| ArgC MShigh |
|
|---|
| LysN MShigh |
|
|---|
| TryLysC MShigh |
|
|---|
General Statistics
Number of major isoforms |
Number of additional isoforms |
Number of all proteins |
Number of amino acids |
Min. Seq. Length |
Max. Seq. Length |
Avg. Seq. Length |
Avg. Mol. Weight |
|---|---|---|---|---|---|---|---|
0 |
2227 |
2227 |
2227 |
2227.0 |
251.51 |
Amino acid frequency
Ala |
Cys |
Asp |
Glu |
Phe |
Gly |
His |
Ile |
Lys |
Leu |
|---|---|---|---|---|---|---|---|---|---|
5.433 ± 0.0 | 1.931 ± 0.0 |
5.882 ± 0.0 | 5.388 ± 0.0 |
5.388 ± 0.0 | 6.197 ± 0.0 |
2.335 ± 0.0 | 6.376 ± 0.0 |
6.107 ± 0.0 | 8.801 ± 0.0 |
Met |
Asn |
Gln |
Pro |
Arg |
Ser |
Thr |
Val |
Trp |
Tyr |
|---|---|---|---|---|---|---|---|---|---|
3.233 ± 0.0 | 4.58 ± 0.0 |
4.311 ± 0.0 | 4.086 ± 0.0 |
3.952 ± 0.0 | 7.678 ± 0.0 |
5.927 ± 0.0 | 7.274 ± 0.0 |
1.617 ± 0.0 | 3.502 ± 0.0 |
Most of the basic statistics you can see at this page can be downloaded from this CSV file
See this proteome in:
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here
| Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 | Contact: Lukasz P. Kozlowski |