Amino acid dipepetide frequency for Daedalea quercina L-15889

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.857AlaAla: 9.857 ± 0.071	1.234AlaCys: 1.234 ± 0.018	4.626AlaAsp: 4.626 ± 0.034	5.346AlaGlu: 5.346 ± 0.04	3.295AlaPhe: 3.295 ± 0.028	6.028AlaGly: 6.028 ± 0.043	2.307AlaHis: 2.307 ± 0.02	4.065AlaIle: 4.065 ± 0.03	3.724AlaLys: 3.724 ± 0.033	8.946AlaLeu: 8.946 ± 0.055	2.103AlaMet: 2.103 ± 0.019	2.748AlaAsn: 2.748 ± 0.027	5.782AlaPro: 5.782 ± 0.05	3.63AlaGln: 3.63 ± 0.037	6.336AlaArg: 6.336 ± 0.048	8.299AlaSer: 8.299 ± 0.053	5.503AlaThr: 5.503 ± 0.035	6.061AlaVal: 6.061 ± 0.04	1.271AlaTrp: 1.271 ± 0.018	2.43AlaTyr: 2.43 ± 0.025	0.0AlaXaa: 0.0 ± 0.0
Cys	1.137CysAla: 1.137 ± 0.016	0.292CysCys: 0.292 ± 0.008	0.672CysAsp: 0.672 ± 0.012	0.617CysGlu: 0.617 ± 0.012	0.464CysPhe: 0.464 ± 0.009	0.987CysGly: 0.987 ± 0.016	0.34CysHis: 0.34 ± 0.009	0.698CysIle: 0.698 ± 0.011	0.494CysLys: 0.494 ± 0.01	1.268CysLeu: 1.268 ± 0.02	0.328CysMet: 0.328 ± 0.007	0.376CysAsn: 0.376 ± 0.008	0.817CysPro: 0.817 ± 0.017	0.441CysGln: 0.441 ± 0.01	0.88CysArg: 0.88 ± 0.015	1.033CysSer: 1.033 ± 0.016	0.833CysThr: 0.833 ± 0.015	0.903CysVal: 0.903 ± 0.015	0.209CysTrp: 0.209 ± 0.006	0.354CysTyr: 0.354 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	5.479AspAla: 5.479 ± 0.031	0.608AspCys: 0.608 ± 0.011	4.124AspAsp: 4.124 ± 0.04	4.419AspGlu: 4.419 ± 0.037	1.97AspPhe: 1.97 ± 0.023	4.04AspGly: 4.04 ± 0.032	1.2AspHis: 1.2 ± 0.016	2.817AspIle: 2.817 ± 0.027	1.989AspLys: 1.989 ± 0.025	4.806AspLeu: 4.806 ± 0.034	1.267AspMet: 1.267 ± 0.016	1.493AspAsn: 1.493 ± 0.019	3.43AspPro: 3.43 ± 0.028	1.523AspGln: 1.523 ± 0.018	2.997AspArg: 2.997 ± 0.028	3.841AspSer: 3.841 ± 0.035	2.902AspThr: 2.902 ± 0.021	4.303AspVal: 4.303 ± 0.034	0.899AspTrp: 0.899 ± 0.013	1.471AspTyr: 1.471 ± 0.02	0.0AspXaa: 0.0 ± 0.0
Glu	5.308GluAla: 5.308 ± 0.044	0.669GluCys: 0.669 ± 0.013	4.19GluAsp: 4.19 ± 0.035	5.259GluGlu: 5.259 ± 0.054	1.701GluPhe: 1.701 ± 0.019	3.811GluGly: 3.811 ± 0.027	1.52GluHis: 1.52 ± 0.019	2.54GluIle: 2.54 ± 0.027	2.913GluLys: 2.913 ± 0.034	5.394GluLeu: 5.394 ± 0.038	1.319GluMet: 1.319 ± 0.016	1.747GluAsn: 1.747 ± 0.024	2.882GluPro: 2.882 ± 0.025	2.388GluGln: 2.388 ± 0.025	4.349GluArg: 4.349 ± 0.04	3.834GluSer: 3.834 ± 0.032	3.022GluThr: 3.022 ± 0.026	3.768GluVal: 3.768 ± 0.029	0.912GluTrp: 0.912 ± 0.013	1.559GluTyr: 1.559 ± 0.02	0.0GluXaa: 0.0 ± 0.0
Phe	3.203PheAla: 3.203 ± 0.031	0.523PheCys: 0.523 ± 0.011	2.171PheAsp: 2.171 ± 0.023	1.891PheGlu: 1.891 ± 0.021	1.375PhePhe: 1.375 ± 0.017	2.569PheGly: 2.569 ± 0.029	0.842PheHis: 0.842 ± 0.012	1.565PheIle: 1.565 ± 0.021	1.27PheLys: 1.27 ± 0.017	3.291PheLeu: 3.291 ± 0.029	0.764PheMet: 0.764 ± 0.014	1.169PheAsn: 1.169 ± 0.015	1.946PhePro: 1.946 ± 0.019	1.092PheGln: 1.092 ± 0.014	1.956PheArg: 1.956 ± 0.023	2.847PheSer: 2.847 ± 0.024	2.038PheThr: 2.038 ± 0.022	2.492PheVal: 2.492 ± 0.027	0.562PheTrp: 0.562 ± 0.011	1.027PheTyr: 1.027 ± 0.016	0.0PheXaa: 0.0 ± 0.0
Gly	5.62GlyAla: 5.62 ± 0.041	0.899GlyCys: 0.899 ± 0.015	3.456GlyAsp: 3.456 ± 0.03	3.683GlyGlu: 3.683 ± 0.03	2.42GlyPhe: 2.42 ± 0.027	5.462GlyGly: 5.462 ± 0.058	1.762GlyHis: 1.762 ± 0.021	3.112GlyIle: 3.112 ± 0.027	3.085GlyLys: 3.085 ± 0.026	5.709GlyLeu: 5.709 ± 0.034	1.607GlyMet: 1.607 ± 0.025	1.976GlyAsn: 1.976 ± 0.022	3.53GlyPro: 3.53 ± 0.027	2.376GlyGln: 2.376 ± 0.025	4.433GlyArg: 4.433 ± 0.033	5.637GlySer: 5.637 ± 0.04	4.101GlyThr: 4.101 ± 0.028	4.387GlyVal: 4.387 ± 0.034	1.133GlyTrp: 1.133 ± 0.017	1.902GlyTyr: 1.902 ± 0.022	0.0GlyXaa: 0.0 ± 0.0
His	2.397HisAla: 2.397 ± 0.026	0.378HisCys: 0.378 ± 0.01	1.354HisAsp: 1.354 ± 0.017	1.331HisGlu: 1.331 ± 0.018	0.936HisPhe: 0.936 ± 0.015	1.73HisGly: 1.73 ± 0.018	0.834HisHis: 0.834 ± 0.019	1.263HisIle: 1.263 ± 0.016	0.853HisLys: 0.853 ± 0.015	2.472HisLeu: 2.472 ± 0.03	0.512HisMet: 0.512 ± 0.011	0.74HisAsn: 0.74 ± 0.012	1.941HisPro: 1.941 ± 0.022	0.803HisGln: 0.803 ± 0.013	1.777HisArg: 1.777 ± 0.021	2.054HisSer: 2.054 ± 0.023	1.461HisThr: 1.461 ± 0.019	1.747HisVal: 1.747 ± 0.018	0.369HisTrp: 0.369 ± 0.009	0.7HisTyr: 0.7 ± 0.013	0.0HisXaa: 0.0 ± 0.0
Ile	4.175IleAla: 4.175 ± 0.033	0.716IleCys: 0.716 ± 0.012	2.539IleAsp: 2.539 ± 0.021	2.45IleGlu: 2.45 ± 0.024	1.671IlePhe: 1.671 ± 0.021	2.822IleGly: 2.822 ± 0.027	1.143IleHis: 1.143 ± 0.016	2.171IleIle: 2.171 ± 0.026	1.69IleLys: 1.69 ± 0.021	4.236IleLeu: 4.236 ± 0.034	0.962IleMet: 0.962 ± 0.015	1.37IleAsn: 1.37 ± 0.018	2.983IlePro: 2.983 ± 0.028	1.584IleGln: 1.584 ± 0.02	2.831IleArg: 2.831 ± 0.025	3.377IleSer: 3.377 ± 0.031	2.525IleThr: 2.525 ± 0.025	3.232IleVal: 3.232 ± 0.029	0.682IleTrp: 0.682 ± 0.011	1.255IleTyr: 1.255 ± 0.017	0.0IleXaa: 0.0 ± 0.0
Lys	3.951LysAla: 3.951 ± 0.037	0.44LysCys: 0.44 ± 0.011	2.273LysAsp: 2.273 ± 0.024	2.814LysGlu: 2.814 ± 0.031	1.153LysPhe: 1.153 ± 0.017	2.644LysGly: 2.644 ± 0.024	1.048LysHis: 1.048 ± 0.016	1.718LysIle: 1.718 ± 0.026	2.529LysLys: 2.529 ± 0.032	3.62LysLeu: 3.62 ± 0.03	0.841LysMet: 0.841 ± 0.012	1.182LysAsn: 1.182 ± 0.016	2.391LysPro: 2.391 ± 0.027	1.56LysGln: 1.56 ± 0.021	3.299LysArg: 3.299 ± 0.029	2.786LysSer: 2.786 ± 0.03	2.306LysThr: 2.306 ± 0.025	2.494LysVal: 2.494 ± 0.026	0.597LysTrp: 0.597 ± 0.012	1.162LysTyr: 1.162 ± 0.017	0.0LysXaa: 0.0 ± 0.0
Leu	8.693LeuAla: 8.693 ± 0.05	1.359LeuCys: 1.359 ± 0.019	5.081LeuAsp: 5.081 ± 0.041	5.259LeuGlu: 5.259 ± 0.043	3.262LeuPhe: 3.262 ± 0.029	5.702LeuGly: 5.702 ± 0.042	2.553LeuHis: 2.553 ± 0.026	3.616LeuIle: 3.616 ± 0.031	3.64LeuLys: 3.64 ± 0.033	8.727LeuLeu: 8.727 ± 0.06	1.768LeuMet: 1.768 ± 0.018	2.793LeuAsn: 2.793 ± 0.026	6.228LeuPro: 6.228 ± 0.039	3.673LeuGln: 3.673 ± 0.032	6.626LeuArg: 6.626 ± 0.044	7.822LeuSer: 7.822 ± 0.046	5.243LeuThr: 5.243 ± 0.035	5.989LeuVal: 5.989 ± 0.042	1.247LeuTrp: 1.247 ± 0.016	2.441LeuTyr: 2.441 ± 0.025	0.0LeuXaa: 0.0 ± 0.0
Met	1.958MetAla: 1.958 ± 0.02	0.279MetCys: 0.279 ± 0.008	1.217MetAsp: 1.217 ± 0.016	1.152MetGlu: 1.152 ± 0.016	0.725MetPhe: 0.725 ± 0.013	1.328MetGly: 1.328 ± 0.02	0.585MetHis: 0.585 ± 0.011	0.889MetIle: 0.889 ± 0.014	0.883MetLys: 0.883 ± 0.013	1.988MetLeu: 1.988 ± 0.021	0.519MetMet: 0.519 ± 0.012	0.732MetAsn: 0.732 ± 0.014	1.444MetPro: 1.444 ± 0.016	0.933MetGln: 0.933 ± 0.014	1.456MetArg: 1.456 ± 0.02	2.076MetSer: 2.076 ± 0.022	1.266MetThr: 1.266 ± 0.014	1.273MetVal: 1.273 ± 0.017	0.294MetTrp: 0.294 ± 0.008	0.562MetTyr: 0.562 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	3.042AsnAla: 3.042 ± 0.029	0.361AsnCys: 0.361 ± 0.009	1.53AsnAsp: 1.53 ± 0.022	1.617AsnGlu: 1.617 ± 0.024	1.043AsnPhe: 1.043 ± 0.014	2.428AsnGly: 2.428 ± 0.027	0.697AsnHis: 0.697 ± 0.012	1.639AsnIle: 1.639 ± 0.022	1.138AsnLys: 1.138 ± 0.016	2.741AsnLeu: 2.741 ± 0.025	0.724AsnMet: 0.724 ± 0.014	0.982AsnAsn: 0.982 ± 0.016	2.042AsnPro: 2.042 ± 0.02	0.928AsnGln: 0.928 ± 0.016	1.602AsnArg: 1.602 ± 0.023	2.15AsnSer: 2.15 ± 0.021	1.809AsnThr: 1.809 ± 0.019	2.342AsnVal: 2.342 ± 0.023	0.464AsnTrp: 0.464 ± 0.011	0.84AsnTyr: 0.84 ± 0.015	0.0AsnXaa: 0.0 ± 0.0
Pro	6.25ProAla: 6.25 ± 0.05	0.609ProCys: 0.609 ± 0.013	3.359ProAsp: 3.359 ± 0.025	3.833ProGlu: 3.833 ± 0.031	2.084ProPhe: 2.084 ± 0.022	4.043ProGly: 4.043 ± 0.035	1.648ProHis: 1.648 ± 0.019	2.535ProIle: 2.535 ± 0.02	2.261ProLys: 2.261 ± 0.024	5.417ProLeu: 5.417 ± 0.033	1.176ProMet: 1.176 ± 0.016	1.938ProAsn: 1.938 ± 0.024	6.797ProPro: 6.797 ± 0.073	2.446ProGln: 2.446 ± 0.03	4.178ProArg: 4.178 ± 0.034	7.217ProSer: 7.217 ± 0.069	4.428ProThr: 4.428 ± 0.035	4.131ProVal: 4.131 ± 0.032	0.752ProTrp: 0.752 ± 0.015	1.697ProTyr: 1.697 ± 0.023	0.0ProXaa: 0.0 ± 0.0
Gln	3.507GlnAla: 3.507 ± 0.03	0.476GlnCys: 0.476 ± 0.01	1.878GlnAsp: 1.878 ± 0.02	2.172GlnGlu: 2.172 ± 0.023	1.141GlnPhe: 1.141 ± 0.017	2.183GlnGly: 2.183 ± 0.024	1.041GlnHis: 1.041 ± 0.016	1.558GlnIle: 1.558 ± 0.02	1.489GlnLys: 1.489 ± 0.021	3.449GlnLeu: 3.449 ± 0.027	0.833GlnMet: 0.833 ± 0.013	1.161GlnAsn: 1.161 ± 0.018	2.474GlnPro: 2.474 ± 0.03	1.918GlnGln: 1.918 ± 0.041	2.658GlnArg: 2.658 ± 0.026	2.933GlnSer: 2.933 ± 0.031	2.225GlnThr: 2.225 ± 0.025	2.106GlnVal: 2.106 ± 0.021	0.57GlnTrp: 0.57 ± 0.01	1.106GlnTyr: 1.106 ± 0.016	0.0GlnXaa: 0.0 ± 0.0
Arg	6.123ArgAla: 6.123 ± 0.043	0.927ArgCys: 0.927 ± 0.015	3.476ArgAsp: 3.476 ± 0.03	4.102ArgGlu: 4.102 ± 0.039	2.165ArgPhe: 2.165 ± 0.021	4.075ArgGly: 4.075 ± 0.033	1.766ArgHis: 1.766 ± 0.02	2.939ArgIle: 2.939 ± 0.026	3.272ArgLys: 3.272 ± 0.032	6.089ArgLeu: 6.089 ± 0.038	1.523ArgMet: 1.523 ± 0.019	1.948ArgAsn: 1.948 ± 0.023	4.336ArgPro: 4.336 ± 0.037	2.494ArgGln: 2.494 ± 0.025	6.171ArgArg: 6.171 ± 0.053	5.465ArgSer: 5.465 ± 0.049	3.988ArgThr: 3.988 ± 0.033	4.091ArgVal: 4.091 ± 0.029	1.042ArgTrp: 1.042 ± 0.016	1.701ArgTyr: 1.701 ± 0.019	0.0ArgXaa: 0.0 ± 0.0
Ser	7.786SerAla: 7.786 ± 0.048	0.971SerCys: 0.971 ± 0.015	4.26SerAsp: 4.26 ± 0.035	4.048SerGlu: 4.048 ± 0.027	2.797SerPhe: 2.797 ± 0.024	5.62SerGly: 5.62 ± 0.036	2.002SerHis: 2.002 ± 0.024	3.502SerIle: 3.502 ± 0.029	3.058SerLys: 3.058 ± 0.026	7.551SerLeu: 7.551 ± 0.046	1.813SerMet: 1.813 ± 0.023	2.397SerAsn: 2.397 ± 0.025	6.474SerPro: 6.474 ± 0.069	3.036SerGln: 3.036 ± 0.028	5.553SerArg: 5.553 ± 0.047	9.473SerSer: 9.473 ± 0.1	5.814SerThr: 5.814 ± 0.045	5.293SerVal: 5.293 ± 0.037	1.056SerTrp: 1.056 ± 0.015	2.023SerTyr: 2.023 ± 0.021	0.0SerXaa: 0.0 ± 0.0
Thr	5.526ThrAla: 5.526 ± 0.036	0.793ThrCys: 0.793 ± 0.015	2.793ThrAsp: 2.793 ± 0.026	2.893ThrGlu: 2.893 ± 0.024	2.264ThrPhe: 2.264 ± 0.018	3.897ThrGly: 3.897 ± 0.032	1.479ThrHis: 1.479 ± 0.017	2.797ThrIle: 2.797 ± 0.028	2.124ThrLys: 2.124 ± 0.021	5.749ThrLeu: 5.749 ± 0.037	1.187ThrMet: 1.187 ± 0.016	1.778ThrAsn: 1.778 ± 0.02	4.701ThrPro: 4.701 ± 0.046	2.021ThrGln: 2.021 ± 0.023	3.627ThrArg: 3.627 ± 0.028	5.567ThrSer: 5.567 ± 0.043	4.023ThrThr: 4.023 ± 0.038	4.005ThrVal: 4.005 ± 0.031	0.819ThrTrp: 0.819 ± 0.014	1.648ThrTyr: 1.648 ± 0.02	0.0ThrXaa: 0.0 ± 0.0
Val	5.92ValAla: 5.92 ± 0.041	0.964ValCys: 0.964 ± 0.016	4.006ValAsp: 4.006 ± 0.03	3.904ValGlu: 3.904 ± 0.028	2.507ValPhe: 2.507 ± 0.026	4.056ValGly: 4.056 ± 0.034	1.769ValHis: 1.769 ± 0.018	2.977ValIle: 2.977 ± 0.024	2.719ValLys: 2.719 ± 0.028	6.418ValLeu: 6.418 ± 0.044	1.352ValMet: 1.352 ± 0.015	2.086ValAsn: 2.086 ± 0.023	4.341ValPro: 4.341 ± 0.034	2.547ValGln: 2.547 ± 0.023	4.243ValArg: 4.243 ± 0.031	5.018ValSer: 5.018 ± 0.035	3.684ValThr: 3.684 ± 0.03	4.849ValVal: 4.849 ± 0.04	0.999ValTrp: 0.999 ± 0.014	1.855ValTyr: 1.855 ± 0.023	0.0ValXaa: 0.0 ± 0.0
Trp	1.163TrpAla: 1.163 ± 0.018	0.215TrpCys: 0.215 ± 0.008	0.894TrpAsp: 0.894 ± 0.016	0.825TrpGlu: 0.825 ± 0.013	0.546TrpPhe: 0.546 ± 0.01	0.875TrpGly: 0.875 ± 0.014	0.384TrpHis: 0.384 ± 0.009	0.7TrpIle: 0.7 ± 0.013	0.718TrpLys: 0.718 ± 0.012	1.376TrpLeu: 1.376 ± 0.018	0.366TrpMet: 0.366 ± 0.009	0.557TrpAsn: 0.557 ± 0.011	0.673TrpPro: 0.673 ± 0.013	0.553TrpGln: 0.553 ± 0.012	1.114TrpArg: 1.114 ± 0.016	1.092TrpSer: 1.092 ± 0.017	0.893TrpThr: 0.893 ± 0.014	0.89TrpVal: 0.89 ± 0.015	0.29TrpTrp: 0.29 ± 0.008	0.438TrpTyr: 0.438 ± 0.011	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.496TyrAla: 2.496 ± 0.027	0.43TyrCys: 0.43 ± 0.01	1.678TyrAsp: 1.678 ± 0.02	1.47TyrGlu: 1.47 ± 0.019	1.074TyrPhe: 1.074 ± 0.015	1.99TyrGly: 1.99 ± 0.023	0.731TyrHis: 0.731 ± 0.013	1.314TyrIle: 1.314 ± 0.017	0.961TyrLys: 0.961 ± 0.013	2.474TyrLeu: 2.474 ± 0.024	0.595TyrMet: 0.595 ± 0.011	0.947TyrAsn: 0.947 ± 0.017	1.589TyrPro: 1.589 ± 0.026	0.931TyrGln: 0.931 ± 0.012	1.606TyrArg: 1.606 ± 0.02	2.004TyrSer: 2.004 ± 0.019	1.631TyrThr: 1.631 ± 0.02	1.855TyrVal: 1.855 ± 0.02	0.394TyrTrp: 0.394 ± 0.01	0.906TyrTyr: 0.906 ± 0.017	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 12170 proteins (4971741 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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