Mycobacterium talmoniae

Taxonomy: cellular organisms; Bacteria; Terrabacteria group; Actinobacteria; Actinomycetia; Corynebacteriales; Mycobacteriaceae; Mycobacterium

Average proteome isoelectric point is 6.16

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 5059 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A1S1NLT2|A0A1S1NLT2_9MYCO Uncharacterized protein OS=Mycobacterium talmoniae OX=1858794 GN=BKN37_07030 PE=4 SV=1
MM1 pKa = 7.88RR2 pKa = 11.84NQLARR7 pKa = 11.84FRR9 pKa = 11.84GPTILLATAVAGVIAVAPVTPSVRR33 pKa = 11.84PGQLPDD39 pKa = 3.17IRR41 pKa = 11.84LTADD45 pKa = 3.43DD46 pKa = 5.48ASWQPALDD54 pKa = 3.71QLLDD58 pKa = 3.56AMQQAVAQDD67 pKa = 3.52SALPFATPDD76 pKa = 3.23SAATLMTSLQNTNYY90 pKa = 8.91EE91 pKa = 4.19LLMAGISRR99 pKa = 11.84VTEE102 pKa = 4.14LFNGWFFQSPEE113 pKa = 4.15VVGGDD118 pKa = 3.27AADD121 pKa = 3.61PRR123 pKa = 11.84QYY125 pKa = 11.06FQFFTPDD132 pKa = 2.61IYY134 pKa = 11.44YY135 pKa = 10.32HH136 pKa = 6.0ATAGLAPGATYY147 pKa = 10.82EE148 pKa = 4.13LTGTVGGGTEE158 pKa = 3.92ALAIATEE165 pKa = 4.69EE166 pKa = 4.26ITGSTAVSKK175 pKa = 11.11SSLEE179 pKa = 3.99LGHH182 pKa = 6.48NLVVNPNGTFTVYY195 pKa = 10.33IGPTDD200 pKa = 3.47PSGAVNYY207 pKa = 10.87LNDD210 pKa = 3.86TDD212 pKa = 4.3ATAQGDD218 pKa = 3.86ASLLIRR224 pKa = 11.84DD225 pKa = 3.93MLGNSAQGPTNVSIHH240 pKa = 6.28CVADD244 pKa = 3.91CPAFFAIPSTGLFPGAGDD262 pKa = 3.86SAADD266 pKa = 3.44AAGTSGTQITSLDD279 pKa = 3.79SLLTTLFTAFANIVGPFNSEE299 pKa = 3.58NMGLAQIAGIEE310 pKa = 4.2LPANTMGALTPEE322 pKa = 4.19TSLFATGLPSADD334 pKa = 2.94VSAGNFDD341 pKa = 5.16LDD343 pKa = 3.82PGQALIVKK351 pKa = 9.39VPDD354 pKa = 3.27VAAGYY359 pKa = 10.43SGIEE363 pKa = 3.92LMNVYY368 pKa = 10.17GAGLPSTLAQTTLNNTQAFHH388 pKa = 7.29DD389 pKa = 4.15ADD391 pKa = 4.14GYY393 pKa = 8.75TYY395 pKa = 11.07YY396 pKa = 10.82VVSATNPGVANWLDD410 pKa = 3.53SSGVTRR416 pKa = 11.84GEE418 pKa = 3.41IFARR422 pKa = 11.84FEE424 pKa = 4.02NLPDD428 pKa = 3.81GTDD431 pKa = 3.48PTGLPVTTQVVPVDD445 pKa = 4.1EE446 pKa = 4.57VSHH449 pKa = 5.78YY450 pKa = 11.07LPADD454 pKa = 3.7TPTVSPEE461 pKa = 3.46EE462 pKa = 4.17YY463 pKa = 10.17AADD466 pKa = 3.33MAQRR470 pKa = 11.84VFSYY474 pKa = 10.59DD475 pKa = 3.18YY476 pKa = 11.01ALDD479 pKa = 3.39VSRR482 pKa = 11.84EE483 pKa = 3.87HH484 pKa = 6.91AQPDD488 pKa = 3.62WVIQQLLLHH497 pKa = 6.59GLQGLMGTDD506 pKa = 2.99NYY508 pKa = 11.42DD509 pKa = 3.12AVFGSEE515 pKa = 4.12PVTPLALRR523 pKa = 11.84FSDD526 pKa = 4.34ALSPDD531 pKa = 4.06FGAVLHH537 pKa = 7.09DD538 pKa = 3.86VLTNPVGSLEE548 pKa = 4.16AVINNVPLLASDD560 pKa = 3.58IGLPMEE566 pKa = 4.43LAVGQTVLSLLLPQQLGSLLDD587 pKa = 3.96SVLLDD592 pKa = 3.86PNSGIVAGLLNARR605 pKa = 11.84DD606 pKa = 4.18DD607 pKa = 4.04LATAILTANGGFPTEE622 pKa = 4.87LGVQAAQEE630 pKa = 4.07WANMAEE636 pKa = 4.77LVSSTPITTLADD648 pKa = 3.8LGSLFSLVDD657 pKa = 4.03FPWW660 pKa = 5.08

Molecular weight: 68.82 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A1S1NCA5|A0A1S1NCA5_9MYCO Transporter OS=Mycobacterium talmoniae OX=1858794 GN=BKN37_15780 PE=3 SV=1
MM1 pKa = 7.52AFVLAHH7 pKa = 7.09PIPTARR13 pKa = 11.84RR14 pKa = 11.84STLLHH19 pKa = 6.74AGRR22 pKa = 11.84TAASRR27 pKa = 11.84LWARR31 pKa = 11.84RR32 pKa = 11.84TPQQRR37 pKa = 11.84AAAYY41 pKa = 8.43VSRR44 pKa = 11.84MPVAVITASLGGHH57 pKa = 4.94PTHH60 pKa = 7.47RR61 pKa = 11.84RR62 pKa = 11.84GG63 pKa = 3.62

Molecular weight: 6.85 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

5059

0

5059

1588304

29

3683

314.0

33.69

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

13.627 ± 0.052

0.819 ± 0.01

6.365 ± 0.027

4.91 ± 0.03

3.017 ± 0.016

8.819 ± 0.032

2.308 ± 0.018

4.081 ± 0.022

2.077 ± 0.022

9.997 ± 0.038

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.963 ± 0.014

2.15 ± 0.019

5.95 ± 0.029

3.129 ± 0.019

7.388 ± 0.035

4.95 ± 0.023

6.062 ± 0.024

8.658 ± 0.035

1.526 ± 0.015

2.205 ± 0.017
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski