Amino acid dipepetide frequency for Torque teno virus 29

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.16AlaAla: 6.16 ± 9.792
1.027AlaCys: 1.027 ± 0.528
4.107AlaAsp: 4.107 ± 4.995
2.053AlaGlu: 2.053 ± 3.242
2.053AlaPhe: 2.053 ± 1.887
4.107AlaGly: 4.107 ± 4.995
1.027AlaHis: 1.027 ± 0.528
5.133AlaIle: 5.133 ± 2.603
0.0AlaLys: 0.0 ± 0.0
5.133AlaLeu: 5.133 ± 1.394
0.0AlaMet: 0.0 ± 0.0
1.027AlaAsn: 1.027 ± 0.528
7.187AlaPro: 7.187 ± 4.893
3.08AlaGln: 3.08 ± 1.553
2.053AlaArg: 2.053 ± 1.057
3.08AlaSer: 3.08 ± 2.714
1.027AlaThr: 1.027 ± 0.528
3.08AlaVal: 3.08 ± 1.21
1.027AlaTrp: 1.027 ± 0.528
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
4.107CysGly: 4.107 ± 2.873
1.027CysHis: 1.027 ± 2.295
2.053CysIle: 2.053 ± 1.057
1.027CysLys: 1.027 ± 0.528
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
1.027CysAsn: 1.027 ± 0.528
0.0CysPro: 0.0 ± 0.0
1.027CysGln: 1.027 ± 0.528
0.0CysArg: 0.0 ± 0.0
2.053CysSer: 2.053 ± 1.057
1.027CysThr: 1.027 ± 0.528
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
1.027AspAla: 1.027 ± 1.794
0.0AspCys: 0.0 ± 0.0
5.133AspAsp: 5.133 ± 2.603
2.053AspGlu: 2.053 ± 1.436
2.053AspPhe: 2.053 ± 1.436
1.027AspGly: 1.027 ± 1.794
0.0AspHis: 0.0 ± 0.0
2.053AspIle: 2.053 ± 1.057
1.027AspLys: 1.027 ± 0.528
4.107AspLeu: 4.107 ± 1.194
4.107AspMet: 4.107 ± 1.194
0.0AspAsn: 0.0 ± 0.0
5.133AspPro: 5.133 ± 1.394
2.053AspGln: 2.053 ± 1.436
1.027AspArg: 1.027 ± 0.528
3.08AspSer: 3.08 ± 1.553
4.107AspThr: 4.107 ± 2.114
2.053AspVal: 2.053 ± 1.057
5.133AspTrp: 5.133 ± 2.642
1.027AspTyr: 1.027 ± 0.528
0.0AspXaa: 0.0 ± 0.0
Glu
3.08GluAla: 3.08 ± 1.553
0.0GluCys: 0.0 ± 0.0
3.08GluAsp: 3.08 ± 3.207
1.027GluGlu: 1.027 ± 2.295
0.0GluPhe: 0.0 ± 0.0
3.08GluGly: 3.08 ± 1.21
1.027GluHis: 1.027 ± 0.528
1.027GluIle: 1.027 ± 0.528
3.08GluLys: 3.08 ± 1.553
2.053GluLeu: 2.053 ± 1.436
0.0GluMet: 0.0 ± 0.0
3.08GluAsn: 3.08 ± 1.21
3.08GluPro: 3.08 ± 2.714
4.107GluGln: 4.107 ± 2.114
0.0GluArg: 0.0 ± 0.0
5.133GluSer: 5.133 ± 3.415
2.053GluThr: 2.053 ± 4.59
2.053GluVal: 2.053 ± 1.057
0.0GluTrp: 0.0 ± 0.0
3.08GluTyr: 3.08 ± 1.585
0.0GluXaa: 0.0 ± 0.0
Phe
2.053PheAla: 2.053 ± 3.589
1.027PheCys: 1.027 ± 0.528
1.027PheAsp: 1.027 ± 0.528
1.027PheGlu: 1.027 ± 0.528
0.0PhePhe: 0.0 ± 0.0
0.0PheGly: 0.0 ± 0.0
2.053PheHis: 2.053 ± 1.436
1.027PheIle: 1.027 ± 0.528
1.027PheLys: 1.027 ± 0.528
2.053PheLeu: 2.053 ± 1.057
0.0PheMet: 0.0 ± 0.0
0.0PheAsn: 0.0 ± 0.0
2.053PhePro: 2.053 ± 1.887
2.053PheGln: 2.053 ± 1.057
1.027PheArg: 1.027 ± 0.528
3.08PheSer: 3.08 ± 2.714
2.053PheThr: 2.053 ± 1.057
2.053PheVal: 2.053 ± 1.436
0.0PheTrp: 0.0 ± 0.0
1.027PheTyr: 1.027 ± 0.528
0.0PheXaa: 0.0 ± 0.0
Gly
3.08GlyAla: 3.08 ± 3.207
1.027GlyCys: 1.027 ± 1.794
3.08GlyAsp: 3.08 ± 1.21
1.027GlyGlu: 1.027 ± 1.794
0.0GlyPhe: 0.0 ± 0.0
8.214GlyGly: 8.214 ± 9.99
2.053GlyHis: 2.053 ± 3.589
3.08GlyIle: 3.08 ± 1.585
3.08GlyLys: 3.08 ± 1.553
6.16GlyLeu: 6.16 ± 3.183
1.027GlyMet: 1.027 ± 0.528
2.053GlyAsn: 2.053 ± 1.057
9.24GlyPro: 9.24 ± 6.198
2.053GlyGln: 2.053 ± 1.057
5.133GlyArg: 5.133 ± 1.394
6.16GlySer: 6.16 ± 1.521
3.08GlyThr: 3.08 ± 1.553
2.053GlyVal: 2.053 ± 1.057
3.08GlyTrp: 3.08 ± 1.585
5.133GlyTyr: 5.133 ± 1.394
0.0GlyXaa: 0.0 ± 0.0
His
1.027HisAla: 1.027 ± 1.794
1.027HisCys: 1.027 ± 0.528
2.053HisAsp: 2.053 ± 1.057
1.027HisGlu: 1.027 ± 0.528
0.0HisPhe: 0.0 ± 0.0
0.0HisGly: 0.0 ± 0.0
1.027HisHis: 1.027 ± 0.528
0.0HisIle: 0.0 ± 0.0
1.027HisLys: 1.027 ± 0.528
1.027HisLeu: 1.027 ± 1.794
1.027HisMet: 1.027 ± 0.528
4.107HisAsn: 4.107 ± 4.197
4.107HisPro: 4.107 ± 1.349
2.053HisGln: 2.053 ± 1.057
3.08HisArg: 3.08 ± 1.585
1.027HisSer: 1.027 ± 1.794
1.027HisThr: 1.027 ± 0.528
0.0HisVal: 0.0 ± 0.0
1.027HisTrp: 1.027 ± 0.528
1.027HisTyr: 1.027 ± 0.528
0.0HisXaa: 0.0 ± 0.0
Ile
4.107IleAla: 4.107 ± 2.873
2.053IleCys: 2.053 ± 1.057
1.027IleAsp: 1.027 ± 0.528
0.0IleGlu: 0.0 ± 0.0
1.027IlePhe: 1.027 ± 0.528
3.08IleGly: 3.08 ± 1.585
0.0IleHis: 0.0 ± 0.0
4.107IleIle: 4.107 ± 2.114
5.133IleLys: 5.133 ± 2.642
2.053IleLeu: 2.053 ± 1.436
1.027IleMet: 1.027 ± 0.528
0.0IleAsn: 0.0 ± 0.0
3.08IlePro: 3.08 ± 1.553
1.027IleGln: 1.027 ± 0.528
1.027IleArg: 1.027 ± 0.528
3.08IleSer: 3.08 ± 1.585
3.08IleThr: 3.08 ± 1.585
3.08IleVal: 3.08 ± 1.585
0.0IleTrp: 0.0 ± 0.0
4.107IleTyr: 4.107 ± 2.114
0.0IleXaa: 0.0 ± 0.0
Lys
1.027LysAla: 1.027 ± 2.295
1.027LysCys: 1.027 ± 0.528
2.053LysAsp: 2.053 ± 1.057
5.133LysGlu: 5.133 ± 1.337
1.027LysPhe: 1.027 ± 0.528
5.133LysGly: 5.133 ± 1.337
2.053LysHis: 2.053 ± 1.887
1.027LysIle: 1.027 ± 0.528
5.133LysLys: 5.133 ± 8.753
6.16LysLeu: 6.16 ± 3.171
2.053LysMet: 2.053 ± 1.057
3.08LysAsn: 3.08 ± 1.553
4.107LysPro: 4.107 ± 1.349
2.053LysGln: 2.053 ± 1.057
9.24LysArg: 9.24 ± 4.658
3.08LysSer: 3.08 ± 1.585
4.107LysThr: 4.107 ± 6.46
1.027LysVal: 1.027 ± 0.528
3.08LysTrp: 3.08 ± 1.585
0.0LysTyr: 0.0 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
4.107LeuAla: 4.107 ± 1.194
0.0LeuCys: 0.0 ± 0.0
6.16LeuAsp: 6.16 ± 2.421
1.027LeuGlu: 1.027 ± 0.528
2.053LeuPhe: 2.053 ± 1.436
2.053LeuGly: 2.053 ± 1.057
1.027LeuHis: 1.027 ± 0.528
4.107LeuIle: 4.107 ± 2.114
4.107LeuLys: 4.107 ± 2.114
6.16LeuLeu: 6.16 ± 3.171
4.107LeuMet: 4.107 ± 2.114
3.08LeuAsn: 3.08 ± 1.21
7.187LeuPro: 7.187 ± 2.345
9.24LeuGln: 9.24 ± 2.691
5.133LeuArg: 5.133 ± 2.642
4.107LeuSer: 4.107 ± 2.114
6.16LeuThr: 6.16 ± 3.171
0.0LeuVal: 0.0 ± 0.0
2.053LeuTrp: 2.053 ± 1.057
6.16LeuTyr: 6.16 ± 5.66
0.0LeuXaa: 0.0 ± 0.0
Met
2.053MetAla: 2.053 ± 1.057
0.0MetCys: 0.0 ± 0.0
2.053MetAsp: 2.053 ± 1.057
1.027MetGlu: 1.027 ± 0.528
0.0MetPhe: 0.0 ± 0.0
3.08MetGly: 3.08 ± 1.585
0.0MetHis: 0.0 ± 0.0
1.027MetIle: 1.027 ± 0.528
1.027MetLys: 1.027 ± 0.528
5.133MetLeu: 5.133 ± 1.337
1.027MetMet: 1.027 ± 3.106
2.053MetAsn: 2.053 ± 1.887
3.08MetPro: 3.08 ± 1.21
0.0MetGln: 0.0 ± 0.0
1.027MetArg: 1.027 ± 0.528
0.0MetSer: 0.0 ± 0.0
1.027MetThr: 1.027 ± 0.528
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
1.027MetTyr: 1.027 ± 0.528
0.0MetXaa: 0.0 ± 0.0
Asn
2.053AsnAla: 2.053 ± 1.436
1.027AsnCys: 1.027 ± 0.528
0.0AsnAsp: 0.0 ± 0.0
0.0AsnGlu: 0.0 ± 0.0
2.053AsnPhe: 2.053 ± 1.057
2.053AsnGly: 2.053 ± 1.057
1.027AsnHis: 1.027 ± 0.528
0.0AsnIle: 0.0 ± 0.0
4.107AsnLys: 4.107 ± 1.349
5.133AsnLeu: 5.133 ± 2.642
1.027AsnMet: 1.027 ± 2.295
3.08AsnAsn: 3.08 ± 1.585
3.08AsnPro: 3.08 ± 1.21
3.08AsnGln: 3.08 ± 1.21
3.08AsnArg: 3.08 ± 1.585
7.187AsnSer: 7.187 ± 6.084
1.027AsnThr: 1.027 ± 0.528
1.027AsnVal: 1.027 ± 1.794
1.027AsnTrp: 1.027 ± 0.528
3.08AsnTyr: 3.08 ± 1.585
0.0AsnXaa: 0.0 ± 0.0
Pro
8.214ProAla: 8.214 ± 8.869
1.027ProCys: 1.027 ± 0.528
3.08ProAsp: 3.08 ± 1.585
7.187ProGlu: 7.187 ± 2.688
3.08ProPhe: 3.08 ± 1.585
5.133ProGly: 5.133 ± 8.972
0.0ProHis: 0.0 ± 0.0
1.027ProIle: 1.027 ± 0.528
6.16ProLys: 6.16 ± 5.66
7.187ProLeu: 7.187 ± 1.843
3.08ProMet: 3.08 ± 1.021
2.053ProAsn: 2.053 ± 1.057
9.24ProPro: 9.24 ± 11.78
1.027ProGln: 1.027 ± 0.528
9.24ProArg: 9.24 ± 3.978
5.133ProSer: 5.133 ± 3.415
3.08ProThr: 3.08 ± 1.585
3.08ProVal: 3.08 ± 1.585
3.08ProTrp: 3.08 ± 1.21
3.08ProTyr: 3.08 ± 1.585
0.0ProXaa: 0.0 ± 0.0
Gln
6.16GlnAla: 6.16 ± 3.171
0.0GlnCys: 0.0 ± 0.0
1.027GlnAsp: 1.027 ± 0.528
6.16GlnGlu: 6.16 ± 1.521
1.027GlnPhe: 1.027 ± 0.528
2.053GlnGly: 2.053 ± 1.887
2.053GlnHis: 2.053 ± 1.436
1.027GlnIle: 1.027 ± 0.528
8.214GlnLys: 8.214 ± 2.245
3.08GlnLeu: 3.08 ± 1.585
0.0GlnMet: 0.0 ± 0.0
2.053GlnAsn: 2.053 ± 1.057
1.027GlnPro: 1.027 ± 0.528
2.053GlnGln: 2.053 ± 1.057
1.027GlnArg: 1.027 ± 0.528
1.027GlnSer: 1.027 ± 0.528
4.107GlnThr: 4.107 ± 2.114
1.027GlnVal: 1.027 ± 0.528
3.08GlnTrp: 3.08 ± 1.21
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
2.053ArgAla: 2.053 ± 1.887
0.0ArgCys: 0.0 ± 0.0
2.053ArgAsp: 2.053 ± 1.057
2.053ArgGlu: 2.053 ± 1.436
1.027ArgPhe: 1.027 ± 1.794
8.214ArgGly: 8.214 ± 0.16
4.107ArgHis: 4.107 ± 2.114
3.08ArgIle: 3.08 ± 1.585
3.08ArgLys: 3.08 ± 1.553
2.053ArgLeu: 2.053 ± 1.057
1.027ArgMet: 1.027 ± 0.528
5.133ArgAsn: 5.133 ± 1.337
5.133ArgPro: 5.133 ± 3.687
2.053ArgGln: 2.053 ± 1.057
27.721ArgArg: 27.721 ± 9.973
4.107ArgSer: 4.107 ± 1.349
3.08ArgThr: 3.08 ± 1.585
6.16ArgVal: 6.16 ± 1.521
3.08ArgTrp: 3.08 ± 1.585
5.133ArgTyr: 5.133 ± 2.642
0.0ArgXaa: 0.0 ± 0.0
Ser
2.053SerAla: 2.053 ± 1.887
1.027SerCys: 1.027 ± 2.295
4.107SerAsp: 4.107 ± 1.349
5.133SerGlu: 5.133 ± 6.05
0.0SerPhe: 0.0 ± 0.0
3.08SerGly: 3.08 ± 1.553
1.027SerHis: 1.027 ± 1.794
6.16SerIle: 6.16 ± 1.134
5.133SerLys: 5.133 ± 6.05
4.107SerLeu: 4.107 ± 2.114
2.053SerMet: 2.053 ± 0.992
5.133SerAsn: 5.133 ± 1.66
6.16SerPro: 6.16 ± 3.171
2.053SerGln: 2.053 ± 1.057
4.107SerArg: 4.107 ± 1.349
13.347SerSer: 13.347 ± 18.963
7.187SerThr: 7.187 ± 2.86
2.053SerVal: 2.053 ± 1.057
3.08SerTrp: 3.08 ± 2.714
3.08SerTyr: 3.08 ± 1.585
0.0SerXaa: 0.0 ± 0.0
Thr
1.027ThrAla: 1.027 ± 0.528
0.0ThrCys: 0.0 ± 0.0
3.08ThrAsp: 3.08 ± 1.585
1.027ThrGlu: 1.027 ± 0.528
4.107ThrPhe: 4.107 ± 1.349
5.133ThrGly: 5.133 ± 1.337
4.107ThrHis: 4.107 ± 2.114
0.0ThrIle: 0.0 ± 0.0
7.187ThrLys: 7.187 ± 1.843
8.214ThrLeu: 8.214 ± 2.245
1.027ThrMet: 1.027 ± 0.528
2.053ThrAsn: 2.053 ± 1.057
4.107ThrPro: 4.107 ± 1.349
1.027ThrGln: 1.027 ± 0.528
3.08ThrArg: 3.08 ± 1.553
3.08ThrSer: 3.08 ± 4.168
5.133ThrThr: 5.133 ± 1.337
1.027ThrVal: 1.027 ± 0.528
1.027ThrTrp: 1.027 ± 0.528
4.107ThrTyr: 4.107 ± 2.114
0.0ThrXaa: 0.0 ± 0.0
Val
2.053ValAla: 2.053 ± 1.057
0.0ValCys: 0.0 ± 0.0
1.027ValAsp: 1.027 ± 0.528
0.0ValGlu: 0.0 ± 0.0
3.08ValPhe: 3.08 ± 1.21
3.08ValGly: 3.08 ± 1.21
1.027ValHis: 1.027 ± 0.528
1.027ValIle: 1.027 ± 0.528
0.0ValLys: 0.0 ± 0.0
3.08ValLeu: 3.08 ± 1.585
0.0ValMet: 0.0 ± 0.0
1.027ValAsn: 1.027 ± 0.528
4.107ValPro: 4.107 ± 1.194
1.027ValGln: 1.027 ± 0.528
5.133ValArg: 5.133 ± 1.337
5.133ValSer: 5.133 ± 2.642
2.053ValThr: 2.053 ± 1.057
2.053ValVal: 2.053 ± 1.057
0.0ValTrp: 0.0 ± 0.0
1.027ValTyr: 1.027 ± 0.528
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
3.08TrpCys: 3.08 ± 1.21
2.053TrpAsp: 2.053 ± 1.057
2.053TrpGlu: 2.053 ± 1.057
1.027TrpPhe: 1.027 ± 1.794
4.107TrpGly: 4.107 ± 2.114
0.0TrpHis: 0.0 ± 0.0
2.053TrpIle: 2.053 ± 1.057
0.0TrpLys: 0.0 ± 0.0
4.107TrpLeu: 4.107 ± 2.114
1.027TrpMet: 1.027 ± 0.528
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
1.027TrpGln: 1.027 ± 0.528
5.133TrpArg: 5.133 ± 1.394
2.053TrpSer: 2.053 ± 1.887
1.027TrpThr: 1.027 ± 0.528
0.0TrpVal: 0.0 ± 0.0
3.08TrpTrp: 3.08 ± 1.585
2.053TrpTyr: 2.053 ± 1.057
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.027TyrAla: 1.027 ± 0.528
0.0TyrCys: 0.0 ± 0.0
0.0TyrAsp: 0.0 ± 0.0
1.027TyrGlu: 1.027 ± 0.528
1.027TyrPhe: 1.027 ± 0.528
3.08TyrGly: 3.08 ± 1.21
2.053TyrHis: 2.053 ± 1.057
3.08TyrIle: 3.08 ± 1.585
2.053TyrLys: 2.053 ± 1.057
1.027TyrLeu: 1.027 ± 0.528
1.027TyrMet: 1.027 ± 0.528
4.107TyrAsn: 4.107 ± 2.114
3.08TyrPro: 3.08 ± 1.553
4.107TyrGln: 4.107 ± 1.349
3.08TyrArg: 3.08 ± 1.585
5.133TyrSer: 5.133 ± 1.337
4.107TyrThr: 4.107 ± 2.114
4.107TyrVal: 4.107 ± 2.114
1.027TyrTrp: 1.027 ± 0.528
2.053TyrTyr: 2.053 ± 1.057
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (975 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski