Amino acid dipepetide frequency for Arachis hypogaea (Peanut)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.081AlaAla: 6.081 ± 0.017	1.17AlaCys: 1.17 ± 0.007	3.011AlaAsp: 3.011 ± 0.01	3.958AlaGlu: 3.958 ± 0.012	2.631AlaPhe: 2.631 ± 0.008	3.801AlaGly: 3.801 ± 0.016	1.304AlaHis: 1.304 ± 0.006	3.755AlaIle: 3.755 ± 0.011	3.776AlaLys: 3.776 ± 0.012	6.189AlaLeu: 6.189 ± 0.014	1.735AlaMet: 1.735 ± 0.006	2.683AlaAsn: 2.683 ± 0.01	2.78AlaPro: 2.78 ± 0.01	2.011AlaGln: 2.011 ± 0.008	3.316AlaArg: 3.316 ± 0.01	5.853AlaSer: 5.853 ± 0.016	3.723AlaThr: 3.723 ± 0.016	4.456AlaVal: 4.456 ± 0.012	0.806AlaTrp: 0.806 ± 0.005	1.823AlaTyr: 1.823 ± 0.008	0.0AlaXaa: 0.0 ± 0.0
Cys	1.032CysAla: 1.032 ± 0.005	0.571CysCys: 0.571 ± 0.005	0.922CysAsp: 0.922 ± 0.006	0.926CysGlu: 0.926 ± 0.006	0.933CysPhe: 0.933 ± 0.005	1.373CysGly: 1.373 ± 0.008	0.546CysHis: 0.546 ± 0.004	1.112CysIle: 1.112 ± 0.005	1.181CysLys: 1.181 ± 0.007	1.953CysLeu: 1.953 ± 0.007	0.518CysMet: 0.518 ± 0.004	0.893CysAsn: 0.893 ± 0.006	0.944CysPro: 0.944 ± 0.005	0.634CysGln: 0.634 ± 0.004	1.152CysArg: 1.152 ± 0.006	1.842CysSer: 1.842 ± 0.008	0.905CysThr: 0.905 ± 0.005	1.148CysVal: 1.148 ± 0.007	0.299CysTrp: 0.299 ± 0.003	0.625CysTyr: 0.625 ± 0.004	0.0CysXaa: 0.0 ± 0.0
Asp	3.549AspAla: 3.549 ± 0.012	0.93AspCys: 0.93 ± 0.006	3.86AspAsp: 3.86 ± 0.015	4.109AspGlu: 4.109 ± 0.014	2.245AspPhe: 2.245 ± 0.008	3.585AspGly: 3.585 ± 0.013	1.353AspHis: 1.353 ± 0.006	3.004AspIle: 3.004 ± 0.01	2.765AspLys: 2.765 ± 0.01	4.876AspLeu: 4.876 ± 0.014	1.346AspMet: 1.346 ± 0.006	2.267AspAsn: 2.267 ± 0.009	2.528AspPro: 2.528 ± 0.008	1.67AspGln: 1.67 ± 0.008	2.425AspArg: 2.425 ± 0.01	4.179AspSer: 4.179 ± 0.013	2.219AspThr: 2.219 ± 0.009	3.605AspVal: 3.605 ± 0.011	0.705AspTrp: 0.705 ± 0.005	1.611AspTyr: 1.611 ± 0.007	0.0AspXaa: 0.0 ± 0.0
Glu	4.712GluAla: 4.712 ± 0.014	1.033GluCys: 1.033 ± 0.006	4.041GluAsp: 4.041 ± 0.013	6.35GluGlu: 6.35 ± 0.02	2.579GluPhe: 2.579 ± 0.009	3.794GluGly: 3.794 ± 0.01	1.308GluHis: 1.308 ± 0.006	3.668GluIle: 3.668 ± 0.011	4.612GluLys: 4.612 ± 0.015	5.832GluLeu: 5.832 ± 0.016	1.759GluMet: 1.759 ± 0.008	3.074GluAsn: 3.074 ± 0.01	2.222GluPro: 2.222 ± 0.009	2.286GluGln: 2.286 ± 0.008	3.359GluArg: 3.359 ± 0.011	4.633GluSer: 4.633 ± 0.014	3.037GluThr: 3.037 ± 0.01	4.11GluVal: 4.11 ± 0.011	0.774GluTrp: 0.774 ± 0.005	1.706GluTyr: 1.706 ± 0.007	0.0GluXaa: 0.0 ± 0.0
Phe	2.476PheAla: 2.476 ± 0.009	0.933PheCys: 0.933 ± 0.006	2.38PheAsp: 2.38 ± 0.009	2.477PheGlu: 2.477 ± 0.01	2.074PhePhe: 2.074 ± 0.009	3.098PheGly: 3.098 ± 0.012	1.257PheHis: 1.257 ± 0.006	2.18PheIle: 2.18 ± 0.009	2.205PheLys: 2.205 ± 0.008	4.29PheLeu: 4.29 ± 0.014	1.024PheMet: 1.024 ± 0.006	1.839PheAsn: 1.839 ± 0.007	2.116PhePro: 2.116 ± 0.008	1.644PheGln: 1.644 ± 0.007	2.234PheArg: 2.234 ± 0.008	3.887PheSer: 3.887 ± 0.012	2.042PheThr: 2.042 ± 0.008	2.879PheVal: 2.879 ± 0.009	0.651PheTrp: 0.651 ± 0.004	1.358PheTyr: 1.358 ± 0.006	0.0PheXaa: 0.0 ± 0.0
Gly	3.565GlyAla: 3.565 ± 0.011	1.347GlyCys: 1.347 ± 0.006	3.367GlyAsp: 3.367 ± 0.01	3.545GlyGlu: 3.545 ± 0.012	2.953GlyPhe: 2.953 ± 0.01	5.054GlyGly: 5.054 ± 0.02	1.56GlyHis: 1.56 ± 0.007	3.475GlyIle: 3.475 ± 0.011	3.843GlyLys: 3.843 ± 0.012	5.371GlyLeu: 5.371 ± 0.015	1.473GlyMet: 1.473 ± 0.007	2.95GlyAsn: 2.95 ± 0.009	2.199GlyPro: 2.199 ± 0.009	1.918GlyGln: 1.918 ± 0.008	3.439GlyArg: 3.439 ± 0.011	5.554GlySer: 5.554 ± 0.016	3.149GlyThr: 3.149 ± 0.01	4.122GlyVal: 4.122 ± 0.013	0.818GlyTrp: 0.818 ± 0.005	2.041GlyTyr: 2.041 ± 0.01	0.0GlyXaa: 0.0 ± 0.0
His	1.505HisAla: 1.505 ± 0.006	0.583HisCys: 0.583 ± 0.004	1.259HisAsp: 1.259 ± 0.006	1.379HisGlu: 1.379 ± 0.006	1.155HisPhe: 1.155 ± 0.006	1.716HisGly: 1.716 ± 0.007	1.261HisHis: 1.261 ± 0.009	1.436HisIle: 1.436 ± 0.006	1.246HisLys: 1.246 ± 0.006	2.534HisLeu: 2.534 ± 0.009	0.646HisMet: 0.646 ± 0.004	1.14HisAsn: 1.14 ± 0.006	1.443HisPro: 1.443 ± 0.006	1.137HisGln: 1.137 ± 0.006	1.587HisArg: 1.587 ± 0.007	2.097HisSer: 2.097 ± 0.008	1.183HisThr: 1.183 ± 0.006	1.704HisVal: 1.704 ± 0.007	0.361HisTrp: 0.361 ± 0.003	0.78HisTyr: 0.78 ± 0.005	0.0HisXaa: 0.0 ± 0.0
Ile	3.459IleAla: 3.459 ± 0.011	1.096IleCys: 1.096 ± 0.006	2.902IleAsp: 2.902 ± 0.01	3.321IleGlu: 3.321 ± 0.009	2.464IlePhe: 2.464 ± 0.009	3.299IleGly: 3.299 ± 0.01	1.459IleHis: 1.459 ± 0.006	3.039IleIle: 3.039 ± 0.01	3.175IleLys: 3.175 ± 0.011	5.298IleLeu: 5.298 ± 0.014	1.314IleMet: 1.314 ± 0.006	2.369IleAsn: 2.369 ± 0.009	3.062IlePro: 3.062 ± 0.012	2.092IleGln: 2.092 ± 0.008	2.846IleArg: 2.846 ± 0.009	4.698IleSer: 4.698 ± 0.013	2.733IleThr: 2.733 ± 0.008	3.487IleVal: 3.487 ± 0.01	0.774IleTrp: 0.774 ± 0.005	1.619IleTyr: 1.619 ± 0.008	0.0IleXaa: 0.0 ± 0.0
Lys	3.828LysAla: 3.828 ± 0.011	1.078LysCys: 1.078 ± 0.006	3.235LysAsp: 3.235 ± 0.009	4.767LysGlu: 4.767 ± 0.015	2.374LysPhe: 2.374 ± 0.007	3.638LysGly: 3.638 ± 0.011	1.396LysHis: 1.396 ± 0.007	3.378LysIle: 3.378 ± 0.011	5.107LysLys: 5.107 ± 0.02	5.843LysLeu: 5.843 ± 0.018	1.525LysMet: 1.525 ± 0.006	2.893LysAsn: 2.893 ± 0.011	2.545LysPro: 2.545 ± 0.009	2.31LysGln: 2.31 ± 0.009	3.787LysArg: 3.787 ± 0.013	4.517LysSer: 4.517 ± 0.015	2.911LysThr: 2.911 ± 0.01	3.871LysVal: 3.871 ± 0.011	0.84LysTrp: 0.84 ± 0.005	1.691LysTyr: 1.691 ± 0.007	0.0LysXaa: 0.0 ± 0.0
Leu	6.16LeuAla: 6.16 ± 0.016	2.026LeuCys: 2.026 ± 0.008	5.032LeuAsp: 5.032 ± 0.014	6.143LeuGlu: 6.143 ± 0.018	3.963LeuPhe: 3.963 ± 0.014	5.478LeuGly: 5.478 ± 0.015	2.703LeuHis: 2.703 ± 0.008	4.663LeuIle: 4.663 ± 0.013	6.042LeuLys: 6.042 ± 0.018	9.708LeuLeu: 9.708 ± 0.024	2.163LeuMet: 2.163 ± 0.008	4.151LeuAsn: 4.151 ± 0.012	5.176LeuPro: 5.176 ± 0.016	4.227LeuGln: 4.227 ± 0.016	5.334LeuArg: 5.334 ± 0.014	8.301LeuSer: 8.301 ± 0.021	4.338LeuThr: 4.338 ± 0.013	6.176LeuVal: 6.176 ± 0.016	1.15LeuTrp: 1.15 ± 0.006	2.554LeuTyr: 2.554 ± 0.01	0.0LeuXaa: 0.0 ± 0.0
Met	1.993MetAla: 1.993 ± 0.007	0.404MetCys: 0.404 ± 0.003	1.394MetAsp: 1.394 ± 0.007	2.011MetGlu: 2.011 ± 0.008	0.915MetPhe: 0.915 ± 0.005	1.461MetGly: 1.461 ± 0.006	0.668MetHis: 0.668 ± 0.004	1.291MetIle: 1.291 ± 0.006	1.798MetLys: 1.798 ± 0.007	2.31MetLeu: 2.31 ± 0.008	0.791MetMet: 0.791 ± 0.005	1.114MetAsn: 1.114 ± 0.005	1.153MetPro: 1.153 ± 0.006	0.953MetGln: 0.953 ± 0.005	1.311MetArg: 1.311 ± 0.007	1.759MetSer: 1.759 ± 0.007	1.061MetThr: 1.061 ± 0.006	1.633MetVal: 1.633 ± 0.007	0.282MetTrp: 0.282 ± 0.003	0.597MetTyr: 0.597 ± 0.004	0.0MetXaa: 0.0 ± 0.0
Asn	2.723AsnAla: 2.723 ± 0.009	0.934AsnCys: 0.934 ± 0.005	2.258AsnAsp: 2.258 ± 0.008	2.725AsnGlu: 2.725 ± 0.01	1.977AsnPhe: 1.977 ± 0.008	3.101AsnGly: 3.101 ± 0.011	1.257AsnHis: 1.257 ± 0.006	2.68AsnIle: 2.68 ± 0.01	2.81AsnLys: 2.81 ± 0.011	4.757AsnLeu: 4.757 ± 0.018	1.225AsnMet: 1.225 ± 0.005	3.125AsnAsn: 3.125 ± 0.017	2.392AsnPro: 2.392 ± 0.009	1.765AsnGln: 1.765 ± 0.007	2.169AsnArg: 2.169 ± 0.009	3.858AsnSer: 3.858 ± 0.012	2.112AsnThr: 2.112 ± 0.008	2.865AsnVal: 2.865 ± 0.01	0.655AsnTrp: 0.655 ± 0.004	1.418AsnTyr: 1.418 ± 0.006	0.0AsnXaa: 0.0 ± 0.0
Pro	2.869ProAla: 2.869 ± 0.011	0.854ProCys: 0.854 ± 0.005	2.252ProAsp: 2.252 ± 0.009	2.996ProGlu: 2.996 ± 0.01	2.045ProPhe: 2.045 ± 0.009	2.353ProGly: 2.353 ± 0.01	1.188ProHis: 1.188 ± 0.006	2.445ProIle: 2.445 ± 0.009	2.752ProLys: 2.752 ± 0.011	4.372ProLeu: 4.372 ± 0.013	0.972ProMet: 0.972 ± 0.005	2.407ProAsn: 2.407 ± 0.009	4.042ProPro: 4.042 ± 0.028	1.884ProGln: 1.884 ± 0.009	2.472ProArg: 2.472 ± 0.009	5.162ProSer: 5.162 ± 0.016	2.748ProThr: 2.748 ± 0.011	2.815ProVal: 2.815 ± 0.009	0.59ProTrp: 0.59 ± 0.004	1.316ProTyr: 1.316 ± 0.007	0.0ProXaa: 0.0 ± 0.0
Gln	2.23GlnAla: 2.23 ± 0.008	0.621GlnCys: 0.621 ± 0.005	1.762GlnAsp: 1.762 ± 0.007	2.531GlnGlu: 2.531 ± 0.01	1.525GlnPhe: 1.525 ± 0.007	2.016GlnGly: 2.016 ± 0.008	1.096GlnHis: 1.096 ± 0.006	2.063GlnIle: 2.063 ± 0.008	2.317GlnLys: 2.317 ± 0.009	3.681GlnLeu: 3.681 ± 0.01	0.971GlnMet: 0.971 ± 0.005	1.836GlnAsn: 1.836 ± 0.008	1.9GlnPro: 1.9 ± 0.009	2.131GlnGln: 2.131 ± 0.013	2.138GlnArg: 2.138 ± 0.009	2.754GlnSer: 2.754 ± 0.011	1.684GlnThr: 1.684 ± 0.007	2.444GlnVal: 2.444 ± 0.008	0.466GlnTrp: 0.466 ± 0.004	1.011GlnTyr: 1.011 ± 0.006	0.0GlnXaa: 0.0 ± 0.0
Arg	3.159ArgAla: 3.159 ± 0.009	1.182ArgCys: 1.182 ± 0.008	2.649ArgAsp: 2.649 ± 0.01	3.462ArgGlu: 3.462 ± 0.012	2.322ArgPhe: 2.322 ± 0.009	3.156ArgGly: 3.156 ± 0.01	1.437ArgHis: 1.437 ± 0.006	3.055ArgIle: 3.055 ± 0.009	3.823ArgLys: 3.823 ± 0.012	4.899ArgLeu: 4.899 ± 0.013	1.397ArgMet: 1.397 ± 0.007	2.671ArgAsn: 2.671 ± 0.009	2.341ArgPro: 2.341 ± 0.009	1.812ArgGln: 1.812 ± 0.007	4.135ArgArg: 4.135 ± 0.016	4.202ArgSer: 4.202 ± 0.014	2.51ArgThr: 2.51 ± 0.008	3.575ArgVal: 3.575 ± 0.011	0.953ArgTrp: 0.953 ± 0.006	1.588ArgTyr: 1.588 ± 0.007	0.0ArgXaa: 0.0 ± 0.0
Ser	4.992SerAla: 4.992 ± 0.013	1.647SerCys: 1.647 ± 0.008	4.257SerAsp: 4.257 ± 0.012	4.741SerGlu: 4.741 ± 0.013	4.064SerPhe: 4.064 ± 0.013	5.24SerGly: 5.24 ± 0.016	2.275SerHis: 2.275 ± 0.008	4.489SerIle: 4.489 ± 0.013	4.9SerLys: 4.9 ± 0.014	8.364SerLeu: 8.364 ± 0.023	2.127SerMet: 2.127 ± 0.008	4.208SerAsn: 4.208 ± 0.012	4.189SerPro: 4.189 ± 0.016	3.182SerGln: 3.182 ± 0.009	4.373SerArg: 4.373 ± 0.013	10.911SerSer: 10.911 ± 0.03	4.538SerThr: 4.538 ± 0.012	5.001SerVal: 5.001 ± 0.012	1.24SerTrp: 1.24 ± 0.007	2.354SerTyr: 2.354 ± 0.008	0.0SerXaa: 0.0 ± 0.0
Thr	3.188ThrAla: 3.188 ± 0.011	0.982ThrCys: 0.982 ± 0.006	2.216ThrAsp: 2.216 ± 0.009	2.659ThrGlu: 2.659 ± 0.009	2.105ThrPhe: 2.105 ± 0.008	2.809ThrGly: 2.809 ± 0.01	1.28ThrHis: 1.28 ± 0.006	2.976ThrIle: 2.976 ± 0.009	2.852ThrLys: 2.852 ± 0.011	4.868ThrLeu: 4.868 ± 0.012	1.237ThrMet: 1.237 ± 0.005	2.269ThrAsn: 2.269 ± 0.008	2.586ThrPro: 2.586 ± 0.011	1.771ThrGln: 1.771 ± 0.007	2.58ThrArg: 2.58 ± 0.01	4.382ThrSer: 4.382 ± 0.012	3.307ThrThr: 3.307 ± 0.013	3.125ThrVal: 3.125 ± 0.009	0.689ThrTrp: 0.689 ± 0.004	1.506ThrTyr: 1.506 ± 0.007	0.0ThrXaa: 0.0 ± 0.0
Val	4.828ValAla: 4.828 ± 0.017	1.169ValCys: 1.169 ± 0.006	3.765ValAsp: 3.765 ± 0.012	4.308ValGlu: 4.308 ± 0.01	2.699ValPhe: 2.699 ± 0.009	4.025ValGly: 4.025 ± 0.013	1.623ValHis: 1.623 ± 0.007	3.435ValIle: 3.435 ± 0.01	3.826ValLys: 3.826 ± 0.012	6.113ValLeu: 6.113 ± 0.014	1.559ValMet: 1.559 ± 0.007	2.671ValAsn: 2.671 ± 0.009	3.242ValPro: 3.242 ± 0.011	2.266ValGln: 2.266 ± 0.008	3.162ValArg: 3.162 ± 0.01	5.14ValSer: 5.14 ± 0.012	3.176ValThr: 3.176 ± 0.009	5.006ValVal: 5.006 ± 0.014	0.794ValTrp: 0.794 ± 0.005	1.956ValTyr: 1.956 ± 0.008	0.0ValXaa: 0.0 ± 0.0
Trp	0.715TrpAla: 0.715 ± 0.004	0.287TrpCys: 0.287 ± 0.003	0.635TrpAsp: 0.635 ± 0.004	0.796TrpGlu: 0.796 ± 0.005	0.659TrpPhe: 0.659 ± 0.005	0.712TrpGly: 0.712 ± 0.005	0.401TrpHis: 0.401 ± 0.003	0.762TrpIle: 0.762 ± 0.005	0.939TrpLys: 0.939 ± 0.005	1.454TrpLeu: 1.454 ± 0.007	0.383TrpMet: 0.383 ± 0.003	0.741TrpAsn: 0.741 ± 0.005	0.474TrpPro: 0.474 ± 0.003	0.456TrpGln: 0.456 ± 0.004	0.907TrpArg: 0.907 ± 0.005	1.028TrpSer: 1.028 ± 0.006	0.669TrpThr: 0.669 ± 0.005	0.859TrpVal: 0.859 ± 0.005	0.28TrpTrp: 0.28 ± 0.003	0.364TrpTyr: 0.364 ± 0.003	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.799TyrAla: 1.799 ± 0.008	0.662TyrCys: 0.662 ± 0.005	1.635TyrAsp: 1.635 ± 0.007	1.683TyrGlu: 1.683 ± 0.007	1.359TyrPhe: 1.359 ± 0.007	2.031TyrGly: 2.031 ± 0.01	0.777TyrHis: 0.777 ± 0.005	1.602TyrIle: 1.602 ± 0.007	1.569TyrLys: 1.569 ± 0.006	2.776TyrLeu: 2.776 ± 0.01	0.732TyrMet: 0.732 ± 0.005	1.505TyrAsn: 1.505 ± 0.007	1.201TyrPro: 1.201 ± 0.006	1.027TyrGln: 1.027 ± 0.005	1.603TyrArg: 1.603 ± 0.007	2.335TyrSer: 2.335 ± 0.008	1.345TyrThr: 1.345 ± 0.006	1.88TyrVal: 1.88 ± 0.008	0.395TyrTrp: 0.395 ± 0.003	1.006TyrTyr: 1.006 ± 0.006	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.005XaaXaa: 0.005 ± 0.001

Statistics based on 97596 proteins (37456558 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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