Human rotavirus C

Taxonomy: Viruses; Riboviria; Orthornavirae; Duplornaviricota; Resentoviricetes; Reovirales; Reoviridae; Sedoreovirinae; Rotavirus; Rotavirus C

Average proteome isoelectric point is 6.29

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 11 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|D0VZZ4|D0VZZ4_9REOV Outer capsid protein VP4 OS=Human rotavirus C OX=10943 GN=VP4 PE=3 SV=2
MM1 pKa = 7.33VCTTLYY7 pKa = 8.12TVCVILFILFIYY19 pKa = 10.33ILLFRR24 pKa = 11.84KK25 pKa = 8.46MFHH28 pKa = 7.25LITDD32 pKa = 4.06TLIVMLILSNCVEE45 pKa = 4.35WSQGQMFIDD54 pKa = 4.65DD55 pKa = 4.11IYY57 pKa = 11.2YY58 pKa = 10.05NGNVEE63 pKa = 4.41TIINSTDD70 pKa = 3.42PFDD73 pKa = 4.46VEE75 pKa = 4.36SLCIYY80 pKa = 9.75FPNAVVGSQGPGKK93 pKa = 10.4SDD95 pKa = 2.77GHH97 pKa = 8.08LNDD100 pKa = 3.7GNYY103 pKa = 10.46AQTIATLFEE112 pKa = 4.43TKK114 pKa = 10.21GFPKK118 pKa = 10.58GSIILKK124 pKa = 9.46TYY126 pKa = 7.58TQTSDD131 pKa = 4.08FINSVEE137 pKa = 4.26MTCSYY142 pKa = 10.97NIVIIPDD149 pKa = 3.7SPNDD153 pKa = 3.66SEE155 pKa = 5.39SIEE158 pKa = 4.82QIAEE162 pKa = 3.94WILNVWRR169 pKa = 11.84CDD171 pKa = 3.57DD172 pKa = 4.06MNLEE176 pKa = 4.3IYY178 pKa = 9.64TYY180 pKa = 9.6EE181 pKa = 3.99QIGINNLWAAFGSDD195 pKa = 4.29CDD197 pKa = 4.41ISVCPLDD204 pKa = 3.68TTSNGIGCSPASTEE218 pKa = 4.12TYY220 pKa = 10.02EE221 pKa = 4.47VVSNDD226 pKa = 3.33TQLTLINVVDD236 pKa = 4.05NVRR239 pKa = 11.84HH240 pKa = 6.38RR241 pKa = 11.84IQMNTAQCKK250 pKa = 9.81LKK252 pKa = 10.97NCIKK256 pKa = 10.93GEE258 pKa = 3.91ARR260 pKa = 11.84LNTALIRR267 pKa = 11.84ISTSSSFDD275 pKa = 3.34NSLSPLNNGQTTRR288 pKa = 11.84SFKK291 pKa = 10.82INAKK295 pKa = 9.15KK296 pKa = 9.06WWTIFYY302 pKa = 9.29TIIDD306 pKa = 4.45YY307 pKa = 11.08INTIVQAMTPRR318 pKa = 11.84HH319 pKa = 5.18RR320 pKa = 11.84AIYY323 pKa = 9.33PEE325 pKa = 3.79GWMLRR330 pKa = 11.84YY331 pKa = 9.45AA332 pKa = 4.23

Molecular weight: 37.56 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A160NTT5|A0A160NTT5_9REOV Non-structural protein 5 OS=Human rotavirus C OX=10943 GN=NSP5 PE=3 SV=1
MM1 pKa = 7.45ANSFRR6 pKa = 11.84EE7 pKa = 3.69MLYY10 pKa = 9.54WYY12 pKa = 10.31RR13 pKa = 11.84KK14 pKa = 9.77IIDD17 pKa = 3.64RR18 pKa = 11.84KK19 pKa = 9.82LPCVNVNIWRR29 pKa = 11.84RR30 pKa = 11.84EE31 pKa = 3.69IEE33 pKa = 4.08YY34 pKa = 10.3KK35 pKa = 11.14ANGVCLNCLNEE46 pKa = 4.79CKK48 pKa = 10.41VCPCDD53 pKa = 3.46YY54 pKa = 10.75CGIRR58 pKa = 11.84HH59 pKa = 5.94KK60 pKa = 11.09CEE62 pKa = 3.44NCLNSDD68 pKa = 4.11CFMNTDD74 pKa = 3.49NEE76 pKa = 4.62FNSHH80 pKa = 5.22RR81 pKa = 11.84WITFDD86 pKa = 4.02EE87 pKa = 5.0EE88 pKa = 4.11PSQMVLFEE96 pKa = 3.83YY97 pKa = 9.86WIMYY101 pKa = 9.91KK102 pKa = 10.47DD103 pKa = 3.64YY104 pKa = 10.65FLSKK108 pKa = 10.48FNYY111 pKa = 9.45NYY113 pKa = 10.52KK114 pKa = 9.94IQLKK118 pKa = 9.07ILNMNKK124 pKa = 9.16NRR126 pKa = 11.84RR127 pKa = 11.84FHH129 pKa = 7.83INEE132 pKa = 4.12SKK134 pKa = 10.67KK135 pKa = 10.41KK136 pKa = 9.48ALSVPITSQYY146 pKa = 11.63LKK148 pKa = 10.79FKK150 pKa = 10.23FNNKK154 pKa = 8.34IYY156 pKa = 10.62IMFGTFLTSKK166 pKa = 8.75IQPWIQLKK174 pKa = 8.78SLKK177 pKa = 10.28VGYY180 pKa = 9.33IQSLNVDD187 pKa = 3.8RR188 pKa = 11.84CAKK191 pKa = 10.54LIATKK196 pKa = 10.81GMFATNSFKK205 pKa = 10.85SSCITEE211 pKa = 3.76INARR215 pKa = 11.84RR216 pKa = 11.84PISEE220 pKa = 4.25CDD222 pKa = 3.59YY223 pKa = 11.23LIEE226 pKa = 5.28ACLCNEE232 pKa = 3.59NNEE235 pKa = 4.35WKK237 pKa = 10.42FSAVMGRR244 pKa = 11.84DD245 pKa = 3.68KK246 pKa = 11.23IPVTKK251 pKa = 10.18SLAMKK256 pKa = 7.77YY257 pKa = 9.59FCKK260 pKa = 10.66NINTEE265 pKa = 3.87LFYY268 pKa = 11.19YY269 pKa = 10.18GHH271 pKa = 7.19AKK273 pKa = 9.52CHH275 pKa = 5.44VVSEE279 pKa = 4.47CPRR282 pKa = 11.84WNQQLRR288 pKa = 11.84VLHH291 pKa = 6.91ASTLNIIFRR300 pKa = 11.84RR301 pKa = 11.84QFMNEE306 pKa = 3.46VVEE309 pKa = 4.18WFEE312 pKa = 5.58NFTQLTGMHH321 pKa = 6.96HH322 pKa = 7.37DD323 pKa = 4.76FIKK326 pKa = 9.28TCVYY330 pKa = 9.97NKK332 pKa = 10.13VIVSHH337 pKa = 5.99FRR339 pKa = 11.84KK340 pKa = 10.18EE341 pKa = 3.63IEE343 pKa = 4.27DD344 pKa = 3.84YY345 pKa = 11.32INFGKK350 pKa = 10.36KK351 pKa = 9.23ISLSSVIPDD360 pKa = 2.95GHH362 pKa = 7.46ALYY365 pKa = 10.95NSIDD369 pKa = 3.66RR370 pKa = 11.84LRR372 pKa = 11.84ISLMLAIDD380 pKa = 3.56VALNRR385 pKa = 11.84IEE387 pKa = 4.11SQQMDD392 pKa = 3.91VLL394 pKa = 4.2

Molecular weight: 46.79 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

11

0

11

5608

150

1090

509.8

58.62

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.456 ± 0.283

1.373 ± 0.339

5.76 ± 0.276

5.617 ± 0.375

4.44 ± 0.225

3.762 ± 0.322

1.819 ± 0.219

8.862 ± 0.355

6.669 ± 0.588

8.06 ± 0.359

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

3.103 ± 0.173

7.4 ± 0.373

2.853 ± 0.3

3.424 ± 0.374

4.547 ± 0.201

7.971 ± 0.481

6.669 ± 0.387

5.831 ± 0.308

1.088 ± 0.168

5.296 ± 0.494
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski