Amino acid dipepetide frequency for Tortoise microvirus 24

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
12.31AlaAla: 12.31 ± 4.566
0.724AlaCys: 0.724 ± 0.723
5.069AlaAsp: 5.069 ± 2.102
3.621AlaGlu: 3.621 ± 1.387
2.172AlaPhe: 2.172 ± 1.441
5.793AlaGly: 5.793 ± 2.109
1.448AlaHis: 1.448 ± 0.627
3.621AlaIle: 3.621 ± 1.166
3.621AlaLys: 3.621 ± 1.544
5.793AlaLeu: 5.793 ± 1.013
2.172AlaMet: 2.172 ± 0.989
2.896AlaAsn: 2.896 ± 1.775
3.621AlaPro: 3.621 ± 2.157
3.621AlaGln: 3.621 ± 1.556
5.069AlaArg: 5.069 ± 1.616
2.172AlaSer: 2.172 ± 1.566
2.896AlaThr: 2.896 ± 1.323
5.069AlaVal: 5.069 ± 2.376
1.448AlaTrp: 1.448 ± 0.961
2.172AlaTyr: 2.172 ± 0.928
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.724CysAsp: 0.724 ± 0.48
0.0CysGlu: 0.0 ± 0.0
1.448CysPhe: 1.448 ± 0.682
2.172CysGly: 2.172 ± 1.32
0.724CysHis: 0.724 ± 0.723
0.724CysIle: 0.724 ± 0.48
0.0CysLys: 0.0 ± 0.0
0.0CysLeu: 0.0 ± 0.0
0.724CysMet: 0.724 ± 0.723
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.724CysArg: 0.724 ± 0.723
0.0CysSer: 0.0 ± 0.0
0.724CysThr: 0.724 ± 0.723
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
5.793AspAla: 5.793 ± 2.332
0.0AspCys: 0.0 ± 0.0
3.621AspAsp: 3.621 ± 1.913
8.689AspGlu: 8.689 ± 3.872
2.172AspPhe: 2.172 ± 1.441
2.896AspGly: 2.896 ± 1.569
0.724AspHis: 0.724 ± 0.48
2.896AspIle: 2.896 ± 1.224
0.724AspLys: 0.724 ± 0.637
5.793AspLeu: 5.793 ± 2.208
0.724AspMet: 0.724 ± 0.48
2.172AspAsn: 2.172 ± 1.544
2.896AspPro: 2.896 ± 1.634
4.345AspGln: 4.345 ± 1.856
6.517AspArg: 6.517 ± 1.449
0.724AspSer: 0.724 ± 0.723
4.345AspThr: 4.345 ± 2.338
4.345AspVal: 4.345 ± 1.469
0.0AspTrp: 0.0 ± 0.0
2.896AspTyr: 2.896 ± 1.571
0.0AspXaa: 0.0 ± 0.0
Glu
2.172GluAla: 2.172 ± 1.442
1.448GluCys: 1.448 ± 1.445
3.621GluAsp: 3.621 ± 1.753
7.241GluGlu: 7.241 ± 2.043
6.517GluPhe: 6.517 ± 1.641
5.069GluGly: 5.069 ± 2.327
1.448GluHis: 1.448 ± 0.682
2.172GluIle: 2.172 ± 1.441
5.793GluLys: 5.793 ± 2.896
5.793GluLeu: 5.793 ± 1.956
1.448GluMet: 1.448 ± 0.627
1.448GluAsn: 1.448 ± 1.196
2.172GluPro: 2.172 ± 1.229
5.793GluGln: 5.793 ± 2.409
3.621GluArg: 3.621 ± 3.004
1.448GluSer: 1.448 ± 1.274
1.448GluThr: 1.448 ± 1.095
4.345GluVal: 4.345 ± 2.292
0.724GluTrp: 0.724 ± 0.723
6.517GluTyr: 6.517 ± 2.361
0.0GluXaa: 0.0 ± 0.0
Phe
1.448PheAla: 1.448 ± 1.095
0.0PheCys: 0.0 ± 0.0
0.724PheAsp: 0.724 ± 0.48
1.448PheGlu: 1.448 ± 0.627
2.172PhePhe: 2.172 ± 0.932
3.621PheGly: 3.621 ± 1.042
0.0PheHis: 0.0 ± 0.0
2.172PheIle: 2.172 ± 0.932
2.172PheLys: 2.172 ± 0.552
2.896PheLeu: 2.896 ± 1.921
1.448PheMet: 1.448 ± 1.123
4.345PheAsn: 4.345 ± 1.715
2.172PhePro: 2.172 ± 1.229
1.448PheGln: 1.448 ± 1.018
3.621PheArg: 3.621 ± 1.767
2.896PheSer: 2.896 ± 1.317
2.172PheThr: 2.172 ± 0.917
3.621PheVal: 3.621 ± 2.055
0.724PheTrp: 0.724 ± 0.48
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
1.448GlyAla: 1.448 ± 0.682
0.724GlyCys: 0.724 ± 0.723
5.069GlyAsp: 5.069 ± 1.92
2.896GlyGlu: 2.896 ± 0.746
3.621GlyPhe: 3.621 ± 2.055
4.345GlyGly: 4.345 ± 2.226
2.896GlyHis: 2.896 ± 0.682
4.345GlyIle: 4.345 ± 1.118
6.517GlyLys: 6.517 ± 3.152
8.689GlyLeu: 8.689 ± 1.414
1.448GlyMet: 1.448 ± 1.274
2.172GlyAsn: 2.172 ± 0.917
1.448GlyPro: 1.448 ± 2.128
4.345GlyGln: 4.345 ± 0.679
5.069GlyArg: 5.069 ± 2.102
3.621GlySer: 3.621 ± 1.749
3.621GlyThr: 3.621 ± 1.166
3.621GlyVal: 3.621 ± 1.166
1.448GlyTrp: 1.448 ± 0.779
2.172GlyTyr: 2.172 ± 1.027
0.0GlyXaa: 0.0 ± 0.0
His
2.172HisAla: 2.172 ± 1.32
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
1.448HisGlu: 1.448 ± 0.682
1.448HisPhe: 1.448 ± 0.961
3.621HisGly: 3.621 ± 1.293
0.0HisHis: 0.0 ± 0.0
0.724HisIle: 0.724 ± 0.723
1.448HisLys: 1.448 ± 0.627
0.0HisLeu: 0.0 ± 0.0
1.448HisMet: 1.448 ± 0.627
0.724HisAsn: 0.724 ± 0.637
0.0HisPro: 0.0 ± 0.0
0.724HisGln: 0.724 ± 0.637
0.724HisArg: 0.724 ± 0.637
0.0HisSer: 0.0 ± 0.0
0.724HisThr: 0.724 ± 0.637
1.448HisVal: 1.448 ± 1.274
0.0HisTrp: 0.0 ± 0.0
1.448HisTyr: 1.448 ± 0.682
0.0HisXaa: 0.0 ± 0.0
Ile
3.621IleAla: 3.621 ± 1.496
0.0IleCys: 0.0 ± 0.0
5.069IleAsp: 5.069 ± 0.768
5.793IleGlu: 5.793 ± 3.273
0.724IlePhe: 0.724 ± 0.48
3.621IleGly: 3.621 ± 1.38
0.0IleHis: 0.0 ± 0.0
2.896IleIle: 2.896 ± 1.363
2.896IleLys: 2.896 ± 1.363
2.896IleLeu: 2.896 ± 1.494
0.724IleMet: 0.724 ± 0.48
1.448IleAsn: 1.448 ± 0.961
2.896IlePro: 2.896 ± 1.253
1.448IleGln: 1.448 ± 0.961
3.621IleArg: 3.621 ± 1.387
2.896IleSer: 2.896 ± 1.323
5.069IleThr: 5.069 ± 1.529
2.172IleVal: 2.172 ± 1.033
0.724IleTrp: 0.724 ± 0.637
2.172IleTyr: 2.172 ± 1.033
0.0IleXaa: 0.0 ± 0.0
Lys
2.172LysAla: 2.172 ± 2.063
0.724LysCys: 0.724 ± 0.48
3.621LysAsp: 3.621 ± 1.173
5.069LysGlu: 5.069 ± 2.644
1.448LysPhe: 1.448 ± 0.961
5.069LysGly: 5.069 ± 2.79
0.0LysHis: 0.0 ± 0.0
2.172LysIle: 2.172 ± 1.275
5.069LysLys: 5.069 ± 3.37
4.345LysLeu: 4.345 ± 2.336
1.448LysMet: 1.448 ± 0.682
3.621LysAsn: 3.621 ± 1.138
1.448LysPro: 1.448 ± 1.018
1.448LysGln: 1.448 ± 1.274
5.069LysArg: 5.069 ± 1.144
2.172LysSer: 2.172 ± 0.552
3.621LysThr: 3.621 ± 1.806
1.448LysVal: 1.448 ± 0.682
1.448LysTrp: 1.448 ± 0.682
2.172LysTyr: 2.172 ± 0.552
0.0LysXaa: 0.0 ± 0.0
Leu
5.793LeuAla: 5.793 ± 1.611
0.0LeuCys: 0.0 ± 0.0
5.069LeuAsp: 5.069 ± 2.536
0.724LeuGlu: 0.724 ± 0.48
2.896LeuPhe: 2.896 ± 0.978
4.345LeuGly: 4.345 ± 1.834
0.724LeuHis: 0.724 ± 0.48
2.172LeuIle: 2.172 ± 0.917
2.896LeuLys: 2.896 ± 1.792
5.793LeuLeu: 5.793 ± 1.013
3.621LeuMet: 3.621 ± 1.998
6.517LeuAsn: 6.517 ± 1.635
4.345LeuPro: 4.345 ± 1.864
4.345LeuGln: 4.345 ± 1.118
3.621LeuArg: 3.621 ± 1.042
3.621LeuSer: 3.621 ± 1.973
4.345LeuThr: 4.345 ± 1.104
5.069LeuVal: 5.069 ± 2.035
2.896LeuTrp: 2.896 ± 1.317
5.069LeuTyr: 5.069 ± 2.566
0.0LeuXaa: 0.0 ± 0.0
Met
2.172MetAla: 2.172 ± 1.229
0.0MetCys: 0.0 ± 0.0
2.172MetAsp: 2.172 ± 1.182
2.172MetGlu: 2.172 ± 1.442
2.172MetPhe: 2.172 ± 1.169
0.724MetGly: 0.724 ± 0.48
0.724MetHis: 0.724 ± 0.48
2.172MetIle: 2.172 ± 1.088
0.0MetLys: 0.0 ± 0.0
2.172MetLeu: 2.172 ± 1.169
0.724MetMet: 0.724 ± 0.637
1.448MetAsn: 1.448 ± 1.274
1.448MetPro: 1.448 ± 1.018
2.896MetGln: 2.896 ± 1.32
1.448MetArg: 1.448 ± 0.682
4.345MetSer: 4.345 ± 1.87
0.724MetThr: 0.724 ± 0.637
4.345MetVal: 4.345 ± 1.088
0.0MetTrp: 0.0 ± 0.0
0.724MetTyr: 0.724 ± 0.48
0.0MetXaa: 0.0 ± 0.0
Asn
6.517AsnAla: 6.517 ± 2.572
0.0AsnCys: 0.0 ± 0.0
1.448AsnAsp: 1.448 ± 1.196
2.896AsnGlu: 2.896 ± 1.323
0.724AsnPhe: 0.724 ± 0.48
0.724AsnGly: 0.724 ± 0.723
0.0AsnHis: 0.0 ± 0.0
2.172AsnIle: 2.172 ± 1.185
2.896AsnLys: 2.896 ± 0.682
2.896AsnLeu: 2.896 ± 0.682
2.896AsnMet: 2.896 ± 0.992
1.448AsnAsn: 1.448 ± 0.682
3.621AsnPro: 3.621 ± 2.472
2.172AsnGln: 2.172 ± 0.928
1.448AsnArg: 1.448 ± 1.018
1.448AsnSer: 1.448 ± 1.344
2.172AsnThr: 2.172 ± 0.917
3.621AsnVal: 3.621 ± 1.042
0.0AsnTrp: 0.0 ± 0.0
2.896AsnTyr: 2.896 ± 0.746
0.0AsnXaa: 0.0 ± 0.0
Pro
2.896ProAla: 2.896 ± 1.323
0.0ProCys: 0.0 ± 0.0
1.448ProAsp: 1.448 ± 1.196
3.621ProGlu: 3.621 ± 1.716
4.345ProPhe: 4.345 ± 1.631
3.621ProGly: 3.621 ± 1.716
1.448ProHis: 1.448 ± 0.779
3.621ProIle: 3.621 ± 1.561
2.896ProLys: 2.896 ± 0.682
3.621ProLeu: 3.621 ± 1.892
2.896ProMet: 2.896 ± 1.317
0.724ProAsn: 0.724 ± 1.064
2.896ProPro: 2.896 ± 1.569
2.172ProGln: 2.172 ± 0.917
2.172ProArg: 2.172 ± 1.182
2.172ProSer: 2.172 ± 2.063
3.621ProThr: 3.621 ± 1.252
2.896ProVal: 2.896 ± 1.896
1.448ProTrp: 1.448 ± 0.961
0.724ProTyr: 0.724 ± 1.064
0.0ProXaa: 0.0 ± 0.0
Gln
5.793GlnAla: 5.793 ± 1.799
0.0GlnCys: 0.0 ± 0.0
0.724GlnAsp: 0.724 ± 0.637
3.621GlnGlu: 3.621 ± 1.764
2.172GlnPhe: 2.172 ± 1.229
4.345GlnGly: 4.345 ± 1.834
1.448GlnHis: 1.448 ± 1.274
2.896GlnIle: 2.896 ± 1.333
5.069GlnLys: 5.069 ± 2.144
3.621GlnLeu: 3.621 ± 1.952
2.896GlnMet: 2.896 ± 3.095
2.172GlnAsn: 2.172 ± 0.917
0.724GlnPro: 0.724 ± 0.48
2.896GlnGln: 2.896 ± 1.323
4.345GlnArg: 4.345 ± 2.282
2.896GlnSer: 2.896 ± 0.746
2.896GlnThr: 2.896 ± 0.746
2.172GlnVal: 2.172 ± 1.182
2.172GlnTrp: 2.172 ± 0.917
1.448GlnTyr: 1.448 ± 1.274
0.0GlnXaa: 0.0 ± 0.0
Arg
4.345ArgAla: 4.345 ± 1.617
0.724ArgCys: 0.724 ± 0.723
5.069ArgAsp: 5.069 ± 2.412
5.793ArgGlu: 5.793 ± 2.81
0.724ArgPhe: 0.724 ± 0.48
1.448ArgGly: 1.448 ± 0.627
2.172ArgHis: 2.172 ± 1.088
3.621ArgIle: 3.621 ± 1.064
0.724ArgLys: 0.724 ± 0.723
7.241ArgLeu: 7.241 ± 2.049
0.0ArgMet: 0.0 ± 0.567
4.345ArgAsn: 4.345 ± 1.635
4.345ArgPro: 4.345 ± 0.918
5.069ArgGln: 5.069 ± 2.962
7.965ArgArg: 7.965 ± 3.033
2.896ArgSer: 2.896 ± 1.692
8.689ArgThr: 8.689 ± 1.575
5.793ArgVal: 5.793 ± 2.235
1.448ArgTrp: 1.448 ± 0.779
4.345ArgTyr: 4.345 ± 1.864
0.0ArgXaa: 0.0 ± 0.0
Ser
3.621SerAla: 3.621 ± 1.767
0.724SerCys: 0.724 ± 0.723
2.896SerAsp: 2.896 ± 2.397
2.172SerGlu: 2.172 ± 0.932
0.724SerPhe: 0.724 ± 0.48
2.172SerGly: 2.172 ± 0.917
0.724SerHis: 0.724 ± 0.637
3.621SerIle: 3.621 ± 1.064
3.621SerLys: 3.621 ± 1.806
3.621SerLeu: 3.621 ± 1.402
1.448SerMet: 1.448 ± 1.196
1.448SerAsn: 1.448 ± 2.128
2.896SerPro: 2.896 ± 1.253
2.896SerGln: 2.896 ± 1.494
4.345SerArg: 4.345 ± 2.889
2.172SerSer: 2.172 ± 1.441
5.793SerThr: 5.793 ± 1.073
1.448SerVal: 1.448 ± 0.682
0.0SerTrp: 0.0 ± 0.0
0.0SerTyr: 0.0 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
3.621ThrAla: 3.621 ± 1.764
0.724ThrCys: 0.724 ± 0.48
5.069ThrAsp: 5.069 ± 1.65
5.069ThrGlu: 5.069 ± 1.959
0.724ThrPhe: 0.724 ± 0.48
10.138ThrGly: 10.138 ± 2.594
0.0ThrHis: 0.0 ± 0.0
0.724ThrIle: 0.724 ± 1.136
2.172ThrLys: 2.172 ± 1.36
2.172ThrLeu: 2.172 ± 2.168
2.172ThrMet: 2.172 ± 1.911
1.448ThrAsn: 1.448 ± 0.961
4.345ThrPro: 4.345 ± 1.42
1.448ThrGln: 1.448 ± 1.274
4.345ThrArg: 4.345 ± 1.653
7.241ThrSer: 7.241 ± 2.789
2.172ThrThr: 2.172 ± 1.169
2.172ThrVal: 2.172 ± 0.552
0.724ThrTrp: 0.724 ± 1.136
3.621ThrTyr: 3.621 ± 1.261
0.0ThrXaa: 0.0 ± 0.0
Val
5.793ValAla: 5.793 ± 3.017
0.724ValCys: 0.724 ± 0.723
4.345ValAsp: 4.345 ± 1.135
5.069ValGlu: 5.069 ± 3.464
0.724ValPhe: 0.724 ± 0.48
2.896ValGly: 2.896 ± 2.443
1.448ValHis: 1.448 ± 0.961
4.345ValIle: 4.345 ± 3.342
2.896ValLys: 2.896 ± 1.557
4.345ValLeu: 4.345 ± 1.382
2.172ValMet: 2.172 ± 0.913
0.724ValAsn: 0.724 ± 1.064
2.896ValPro: 2.896 ± 0.978
2.896ValGln: 2.896 ± 1.253
5.069ValArg: 5.069 ± 1.144
1.448ValSer: 1.448 ± 0.961
4.345ValThr: 4.345 ± 1.41
3.621ValVal: 3.621 ± 1.402
2.172ValTrp: 2.172 ± 1.441
0.724ValTyr: 0.724 ± 0.48
0.0ValXaa: 0.0 ± 0.0
Trp
0.724TrpAla: 0.724 ± 0.723
0.0TrpCys: 0.0 ± 0.0
1.448TrpAsp: 1.448 ± 0.961
2.172TrpGlu: 2.172 ± 0.917
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.724TrpHis: 0.724 ± 0.48
2.172TrpIle: 2.172 ± 0.917
0.724TrpLys: 0.724 ± 0.723
0.724TrpLeu: 0.724 ± 0.48
0.724TrpMet: 0.724 ± 0.637
2.172TrpAsn: 2.172 ± 1.229
2.172TrpPro: 2.172 ± 0.932
0.724TrpGln: 0.724 ± 0.48
2.172TrpArg: 2.172 ± 0.552
0.724TrpSer: 0.724 ± 0.723
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.896TyrAla: 2.896 ± 1.557
1.448TyrCys: 1.448 ± 0.961
5.069TyrAsp: 5.069 ± 0.995
0.724TyrGlu: 0.724 ± 1.064
2.172TyrPhe: 2.172 ± 1.441
2.896TyrGly: 2.896 ± 2.016
1.448TyrHis: 1.448 ± 0.779
1.448TyrIle: 1.448 ± 0.682
1.448TyrLys: 1.448 ± 1.199
1.448TyrLeu: 1.448 ± 1.344
0.724TyrMet: 0.724 ± 1.064
0.724TyrAsn: 0.724 ± 0.48
2.896TyrPro: 2.896 ± 1.921
3.621TyrGln: 3.621 ± 1.764
6.517TyrArg: 6.517 ± 2.314
1.448TyrSer: 1.448 ± 0.779
0.724TyrThr: 0.724 ± 1.136
1.448TyrVal: 1.448 ± 0.682
0.0TyrTrp: 0.0 ± 0.0
2.896TyrTyr: 2.896 ± 1.363
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (1382 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski