Ailuropoda melanoleuca papillomavirus 2

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Omegapapillomavirus; Omegapapillomavirus 1

Average proteome isoelectric point is 6.61

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 5 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A220IGF4|A0A220IGF4_9PAPI Minor capsid protein L2 OS=Ailuropoda melanoleuca papillomavirus 2 OX=2016455 GN=L2 PE=3 SV=1
MM1 pKa = 7.15VKK3 pKa = 10.05VLKK6 pKa = 10.18RR7 pKa = 11.84SKK9 pKa = 10.16RR10 pKa = 11.84ASAEE14 pKa = 3.65QLYY17 pKa = 7.85RR18 pKa = 11.84TCKK21 pKa = 9.55QAGTCPPDD29 pKa = 3.8VIPKK33 pKa = 9.83IEE35 pKa = 3.97QTTIADD41 pKa = 3.69QILKK45 pKa = 9.49YY46 pKa = 10.53GSSAVFFGGLGIGTGSGSGGASGYY70 pKa = 10.29VPIRR74 pKa = 11.84GGAGSSVSVGPRR86 pKa = 11.84IPIRR90 pKa = 11.84PPQIVEE96 pKa = 3.98DD97 pKa = 4.56VITIGPGDD105 pKa = 3.81SSVIGVDD112 pKa = 3.23VSPPQQPVEE121 pKa = 4.02VEE123 pKa = 4.36IIAEE127 pKa = 4.33GGGVPTVPSAADD139 pKa = 3.35TFNVVTSPDD148 pKa = 3.38TSVVSTQPPTVSTPATGASSGGRR171 pKa = 11.84AVQSSQHH178 pKa = 5.42FNNPVFEE185 pKa = 4.85ASTPRR190 pKa = 11.84APSIGEE196 pKa = 4.12TSFSPHH202 pKa = 4.35TTVVAGSSNVGVEE215 pKa = 4.55EE216 pKa = 4.12IPLAEE221 pKa = 4.78FPQSSTPLHH230 pKa = 6.15AVTRR234 pKa = 11.84GATAFTKK241 pKa = 10.23YY242 pKa = 10.43NVYY245 pKa = 9.12TRR247 pKa = 11.84QVPIEE252 pKa = 4.34SPSLYY257 pKa = 9.99TDD259 pKa = 3.37PTNLIAIRR267 pKa = 11.84NPLFDD272 pKa = 4.54IDD274 pKa = 4.89PYY276 pKa = 10.76NASATLEE283 pKa = 4.33ADD285 pKa = 3.84PDD287 pKa = 4.36NIPAPNDD294 pKa = 3.33SRR296 pKa = 11.84FLDD299 pKa = 3.28IFKK302 pKa = 10.32LHH304 pKa = 6.73RR305 pKa = 11.84PAMSRR310 pKa = 11.84TKK312 pKa = 10.29AGKK315 pKa = 9.56IRR317 pKa = 11.84FSRR320 pKa = 11.84IGFSKK325 pKa = 9.93GTVTTRR331 pKa = 11.84AGTNIGGRR339 pKa = 11.84VHH341 pKa = 7.46FYY343 pKa = 10.86HH344 pKa = 7.44DD345 pKa = 4.06FSTIVRR351 pKa = 11.84SSASEE356 pKa = 4.19SIEE359 pKa = 3.98LQPLTVGSDD368 pKa = 3.42TASSSLLSVEE378 pKa = 4.51SVGEE382 pKa = 4.3STFSSDD388 pKa = 4.61PIVSFYY394 pKa = 11.35DD395 pKa = 3.45PEE397 pKa = 6.48ADD399 pKa = 4.62LNLQLEE405 pKa = 4.69VTSDD409 pKa = 3.66SEE411 pKa = 4.22QSFVRR416 pKa = 11.84PSGGSTYY423 pKa = 10.67VDD425 pKa = 3.07NSTSVHH431 pKa = 6.09PVPNSKK437 pKa = 8.03TASHH441 pKa = 6.35TFVPSVPGFPYY452 pKa = 10.06TPIITGVFVSFDD464 pKa = 3.41FWLHH468 pKa = 6.07PSQLLKK474 pKa = 10.52RR475 pKa = 11.84KK476 pKa = 9.84RR477 pKa = 11.84SPFYY481 pKa = 10.6LADD484 pKa = 4.84GIVAAA489 pKa = 5.3

Molecular weight: 51.48 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A220IGF1|A0A220IGF1_9PAPI Replication protein E1 OS=Ailuropoda melanoleuca papillomavirus 2 OX=2016455 GN=E1 PE=3 SV=1
MM1 pKa = 7.25TKK3 pKa = 9.29MRR5 pKa = 11.84EE6 pKa = 4.06TTEE9 pKa = 3.93TLEE12 pKa = 4.06NRR14 pKa = 11.84LGALQDD20 pKa = 3.26KK21 pKa = 10.61MMDD24 pKa = 3.03IYY26 pKa = 11.27EE27 pKa = 4.47KK28 pKa = 10.72GGHH31 pKa = 5.95KK32 pKa = 10.67LEE34 pKa = 4.54DD35 pKa = 3.81QIDD38 pKa = 3.61YY39 pKa = 10.21WLLNRR44 pKa = 11.84KK45 pKa = 8.65EE46 pKa = 4.08NALLFYY52 pKa = 10.66AKK54 pKa = 10.12QKK56 pKa = 10.66GYY58 pKa = 8.45KK59 pKa = 8.78TLGLQPVPPLLVSKK73 pKa = 9.55EE74 pKa = 4.0KK75 pKa = 10.91ASIAIEE81 pKa = 3.96MHH83 pKa = 6.93LLLCSLQDD91 pKa = 3.49SEE93 pKa = 5.65YY94 pKa = 10.45GTLPWTITDD103 pKa = 3.91TSRR106 pKa = 11.84EE107 pKa = 4.07MYY109 pKa = 9.64EE110 pKa = 4.24SKK112 pKa = 10.55PEE114 pKa = 3.77KK115 pKa = 9.38TFKK118 pKa = 10.62KK119 pKa = 9.6RR120 pKa = 11.84GVHH123 pKa = 5.92VRR125 pKa = 11.84VLYY128 pKa = 10.83DD129 pKa = 4.0DD130 pKa = 4.13MQSQQVEE137 pKa = 4.45YY138 pKa = 10.5VCWLEE143 pKa = 4.55VYY145 pKa = 10.28FWDD148 pKa = 5.4CDD150 pKa = 3.56NAKK153 pKa = 9.28WGCGSSGVDD162 pKa = 2.91AHH164 pKa = 6.67GVFWTLKK171 pKa = 8.55GQKK174 pKa = 9.51KK175 pKa = 9.86YY176 pKa = 11.34YY177 pKa = 10.6EE178 pKa = 4.51NFDD181 pKa = 3.61KK182 pKa = 11.17DD183 pKa = 3.45ANKK186 pKa = 10.41YY187 pKa = 10.31GKK189 pKa = 7.96TGCWTVNFKK198 pKa = 11.3NEE200 pKa = 3.94TFRR203 pKa = 11.84FSTSASPVGKK213 pKa = 9.12PVSAAANDD221 pKa = 4.08STDD224 pKa = 2.53GRR226 pKa = 11.84APDD229 pKa = 4.11EE230 pKa = 4.62PGCPQEE236 pKa = 5.84AEE238 pKa = 4.14APVCAKK244 pKa = 10.25RR245 pKa = 11.84QADD248 pKa = 3.95GATHH252 pKa = 6.67CGEE255 pKa = 4.03APRR258 pKa = 11.84LGEE261 pKa = 3.7QQGEE265 pKa = 4.08HH266 pKa = 6.61RR267 pKa = 11.84PPEE270 pKa = 3.9KK271 pKa = 9.9RR272 pKa = 11.84RR273 pKa = 11.84RR274 pKa = 11.84ASSASEE280 pKa = 4.25GEE282 pKa = 4.07RR283 pKa = 11.84GQHH286 pKa = 4.69GKK288 pKa = 9.19QRR290 pKa = 11.84VWGRR294 pKa = 11.84RR295 pKa = 11.84QDD297 pKa = 3.73CAPSSGSVHH306 pKa = 6.11TEE308 pKa = 3.75PTCTPVQLLQQQQQQQQQRR327 pKa = 11.84QQHH330 pKa = 6.04KK331 pKa = 9.24KK332 pKa = 8.24QQLHH336 pKa = 5.29EE337 pKa = 4.21QQHH340 pKa = 4.51QQQDD344 pKa = 3.16RR345 pKa = 11.84DD346 pKa = 3.72EE347 pKa = 4.43QEE349 pKa = 3.51EE350 pKa = 4.4DD351 pKa = 3.25EE352 pKa = 5.02AGVVGDD358 pKa = 4.56PGVHH362 pKa = 6.22LSGGNTTQPASTPLPVAVLSGNANQLKK389 pKa = 9.86CYY391 pKa = 10.15RR392 pKa = 11.84YY393 pKa = 9.89RR394 pKa = 11.84LNKK397 pKa = 9.39RR398 pKa = 11.84HH399 pKa = 6.93RR400 pKa = 11.84DD401 pKa = 3.38LILYY405 pKa = 9.97ISTTWYY411 pKa = 5.4WTSNSGQHH419 pKa = 5.02KK420 pKa = 6.06TAKK423 pKa = 7.34ITVMFKK429 pKa = 9.59STACRR434 pKa = 11.84DD435 pKa = 3.5MFKK438 pKa = 10.87KK439 pKa = 10.45KK440 pKa = 10.25VVLPKK445 pKa = 10.71GVTITHH451 pKa = 6.81GAMAFF456 pKa = 3.44

Molecular weight: 51.69 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

5

0

5

2213

141

621

442.6

49.3

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

7.004 ± 0.332

2.44 ± 0.67

5.558 ± 0.262

5.513 ± 0.586

4.022 ± 0.453

6.914 ± 0.443

2.169 ± 0.267

3.705 ± 0.714

6.01 ± 0.847

7.727 ± 0.866

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.898 ± 0.376

4.338 ± 0.655

6.055 ± 0.901

4.88 ± 0.896

5.061 ± 0.261

8.134 ± 1.305

6.281 ± 0.698

7.004 ± 0.706

1.672 ± 0.45

3.615 ± 0.517
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski