Megrivirus A (isolate Turkey/USA/124/2008) (Turkey hepatitis virus 2993D (isolate 124))

Taxonomy: Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes; Picornavirales; Picornaviridae; Megrivirus; Melegrivirus A

Average proteome isoelectric point is 5.19

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 1 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

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* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    

Protein with the lowest isoelectric point:
>tr|E9L812|E9L812_MEGR1 Capsid protein VP0 OS=Megrivirus A (isolate Turkey/USA/124/2008) OX=980964 PE=4 SV=1
MM1 pKa = 7.57SYY3 pKa = 10.53KK4 pKa = 10.56PEE6 pKa = 4.8DD7 pKa = 3.65NAPLQSQQEE16 pKa = 4.22DD17 pKa = 3.86KK18 pKa = 11.01APSVAPHH25 pKa = 6.44EE26 pKa = 4.49KK27 pKa = 9.57ATVEE31 pKa = 4.2TTVAAVVQSEE41 pKa = 4.03QDD43 pKa = 3.77VIFDD47 pKa = 3.97NSWTDD52 pKa = 2.99VRR54 pKa = 11.84TIDD57 pKa = 4.31AEE59 pKa = 3.96IPRR62 pKa = 11.84IVATYY67 pKa = 10.27SWTSTQASGDD77 pKa = 3.65FLTAVTGSDD86 pKa = 3.3AVEE89 pKa = 4.26TLPSSPNPFCLPNYY103 pKa = 10.07LIVNQPASSSGLNVPAQVGLFQALFTRR130 pKa = 11.84HH131 pKa = 5.39ALYY134 pKa = 10.48RR135 pKa = 11.84SGFRR139 pKa = 11.84VEE141 pKa = 3.97VTVNGTQFHH150 pKa = 6.45GGSLFVVAIPHH161 pKa = 5.39PHH163 pKa = 5.59VWMQSLTNTDD173 pKa = 3.14AGTQKK178 pKa = 10.58KK179 pKa = 6.43WTALEE184 pKa = 3.97LVQVNQLGIFPSARR198 pKa = 11.84LLPRR202 pKa = 11.84NASAVALDD210 pKa = 4.1LPYY213 pKa = 10.78VGPAPQLEE221 pKa = 4.37TAALDD226 pKa = 3.4VMYY229 pKa = 10.47AIAILVEE236 pKa = 4.5TPLSIPTGTAPTLTVVMRR254 pKa = 11.84VGATNAHH261 pKa = 6.33FFAPKK266 pKa = 9.9PYY268 pKa = 8.82QTPQSNLGAFDD279 pKa = 3.89VPLDD283 pKa = 3.86VPAPASLLQGVRR295 pKa = 11.84VNTAQSAFVNTSSGSIAQIEE315 pKa = 4.19RR316 pKa = 11.84RR317 pKa = 11.84SRR319 pKa = 11.84STEE322 pKa = 3.86TTFLPARR329 pKa = 11.84VEE331 pKa = 4.0DD332 pKa = 3.49WRR334 pKa = 11.84SILSRR339 pKa = 11.84PTLMSLVQFTAATTLGTNIFQTNVCPTGTSVTNRR373 pKa = 11.84DD374 pKa = 3.12ATQALPNASIKK385 pKa = 10.33RR386 pKa = 11.84LQGTPYY392 pKa = 10.42LSQLARR398 pKa = 11.84YY399 pKa = 8.09FSQWRR404 pKa = 11.84GSLTYY409 pKa = 9.44TFEE412 pKa = 4.12YY413 pKa = 10.03TGPQVSSGRR422 pKa = 11.84LLIAFLPGRR431 pKa = 11.84VRR433 pKa = 11.84AAKK436 pKa = 9.86SGQGAEE442 pKa = 4.18YY443 pKa = 10.82VEE445 pKa = 4.52TGALLQNFTEE455 pKa = 4.22NLHH458 pKa = 6.41VIWDD462 pKa = 4.36LSNSTSVSITCPYY475 pKa = 10.58AIATPWAPIVINSWQAIPLSGYY497 pKa = 10.76SSGTLVAVVMSPLVTPTVVAPTSTILVHH525 pKa = 6.68LSAGSDD531 pKa = 3.35FEE533 pKa = 4.39MRR535 pKa = 11.84FPAPIPVNTIPMYY548 pKa = 10.81NGIVDD553 pKa = 3.62QGPAVDD559 pKa = 5.44DD560 pKa = 4.24LPQGEE565 pKa = 5.15HH566 pKa = 6.8YY567 pKa = 9.17LTAMDD572 pKa = 4.08TMSLQTFFNQSRR584 pKa = 11.84FYY586 pKa = 11.53GNFSATAGTTASMVTIPLSLISFAPSSNLKK616 pKa = 10.23VPEE619 pKa = 4.11APVRR623 pKa = 11.84MFAGLFTFLRR633 pKa = 11.84ADD635 pKa = 3.35LRR637 pKa = 11.84ITVGIPFQHH646 pKa = 6.12NLIVTYY652 pKa = 10.02RR653 pKa = 11.84PPTATPSTYY662 pKa = 10.56SAAGAGAPDD671 pKa = 3.71SAASLLNGPSVILSTRR687 pKa = 11.84ASNMGVEE694 pKa = 4.52FVIPFSAFASVFQTSWSQANRR715 pKa = 11.84VDD717 pKa = 3.29TRR719 pKa = 11.84YY720 pKa = 10.75NPDD723 pKa = 3.43SNQTNPGDD731 pKa = 3.36MGTIFVASRR740 pKa = 11.84LPSAQLSNVSVFIAFQNAEE759 pKa = 4.18FFVPRR764 pKa = 11.84PFPPLTSTGWDD775 pKa = 3.08GTAPNNLEE783 pKa = 3.89GEE785 pKa = 4.45FWEE788 pKa = 5.1EE789 pKa = 3.47EE790 pKa = 4.11DD791 pKa = 3.5PTPVEE796 pKa = 4.34FQAPTTEE803 pKa = 4.09GLEE806 pKa = 4.29KK807 pKa = 10.47GDD809 pKa = 3.62QVMLSVTLDD818 pKa = 3.06ILDD821 pKa = 4.79SIRR824 pKa = 11.84EE825 pKa = 4.19LCSEE829 pKa = 3.98LMEE832 pKa = 5.21NVDD835 pKa = 3.64TLYY838 pKa = 11.25GRR840 pKa = 11.84ARR842 pKa = 11.84AAKK845 pKa = 9.08FAWLVQSTFEE855 pKa = 3.91EE856 pKa = 4.54WKK858 pKa = 11.07KK859 pKa = 10.85NDD861 pKa = 3.05QDD863 pKa = 3.63ADD865 pKa = 3.75EE866 pKa = 5.02FFSDD870 pKa = 3.58VSLVEE875 pKa = 3.92PVVFQSPPSPSARR888 pKa = 11.84EE889 pKa = 3.37KK890 pKa = 10.57AARR893 pKa = 11.84LEE895 pKa = 4.05EE896 pKa = 4.42FFDD899 pKa = 3.68YY900 pKa = 10.0MYY902 pKa = 11.28GCVEE906 pKa = 4.21SEE908 pKa = 4.41EE909 pKa = 4.24EE910 pKa = 3.89LHH912 pKa = 6.75AVCDD916 pKa = 3.84AVNAVIDD923 pKa = 3.88SFYY926 pKa = 11.24DD927 pKa = 3.23SDD929 pKa = 4.03GDD931 pKa = 4.02FIGEE935 pKa = 3.65IRR937 pKa = 11.84DD938 pKa = 3.64RR939 pKa = 11.84FLEE942 pKa = 4.45LPLSYY947 pKa = 10.73PEE949 pKa = 5.02GPDD952 pKa = 3.23HH953 pKa = 7.1AGVWFRR959 pKa = 11.84GEE961 pKa = 4.6FYY963 pKa = 10.56RR964 pKa = 11.84CLYY967 pKa = 9.19VTTQNRR973 pKa = 11.84FFPQVAAYY981 pKa = 10.22SPVEE985 pKa = 4.09TEE987 pKa = 4.29HH988 pKa = 7.66NLFALYY994 pKa = 9.5EE995 pKa = 3.97ALRR998 pKa = 11.84QFEE1001 pKa = 4.86LMCIADD1007 pKa = 4.13PLSTSHH1013 pKa = 7.15HH1014 pKa = 4.82YY1015 pKa = 10.17QRR1017 pKa = 11.84LLFLLLQQQWVIPEE1031 pKa = 4.05MKK1033 pKa = 10.67SMVRR1037 pKa = 11.84EE1038 pKa = 3.96KK1039 pKa = 10.96LAFLYY1044 pKa = 10.64TMVAHH1049 pKa = 6.94PEE1051 pKa = 4.06RR1052 pKa = 11.84IFLDD1056 pKa = 3.7WNWEE1060 pKa = 4.07LFHH1063 pKa = 6.1TQPFRR1068 pKa = 11.84YY1069 pKa = 7.93ICNMVGVEE1077 pKa = 4.24TALTDD1082 pKa = 3.87DD1083 pKa = 4.74GFFSGDD1089 pKa = 3.32EE1090 pKa = 4.11EE1091 pKa = 4.99GQFQAPTSCDD1101 pKa = 3.2QKK1103 pKa = 11.14FLNLVRR1109 pKa = 11.84AYY1111 pKa = 10.09RR1112 pKa = 11.84DD1113 pKa = 3.37AMIVNPWHH1121 pKa = 5.82TFEE1124 pKa = 3.86VCYY1127 pKa = 10.52ISFYY1131 pKa = 11.47DD1132 pKa = 3.58LTCRR1136 pKa = 11.84SDD1138 pKa = 3.31VPEE1141 pKa = 3.92WFKK1144 pKa = 11.14RR1145 pKa = 11.84AVEE1148 pKa = 4.09DD1149 pKa = 3.58ACFDD1153 pKa = 3.95TLCARR1158 pKa = 11.84VAEE1161 pKa = 4.07RR1162 pKa = 11.84VNVNNEE1168 pKa = 3.74VLIEE1172 pKa = 4.45RR1173 pKa = 11.84YY1174 pKa = 9.1RR1175 pKa = 11.84QLYY1178 pKa = 10.52DD1179 pKa = 3.85EE1180 pKa = 5.2IFSEE1184 pKa = 4.67EE1185 pKa = 4.2PDD1187 pKa = 3.64FFSDD1191 pKa = 4.95DD1192 pKa = 4.03EE1193 pKa = 4.98IDD1195 pKa = 5.36AEE1197 pKa = 4.46FQAPKK1202 pKa = 9.8PPAPASSVPVPRR1214 pKa = 11.84PSTPLPSPATSEE1226 pKa = 4.97DD1227 pKa = 3.73EE1228 pKa = 5.56DD1229 pKa = 3.96EE1230 pKa = 6.38GEE1232 pKa = 5.37DD1233 pKa = 4.17EE1234 pKa = 5.02PDD1236 pKa = 4.97DD1237 pKa = 3.61ICVYY1241 pKa = 10.76YY1242 pKa = 10.68VDD1244 pKa = 3.78NGLYY1248 pKa = 9.71RR1249 pKa = 11.84HH1250 pKa = 5.99WGIRR1254 pKa = 11.84NKK1256 pKa = 9.88QQAISLKK1263 pKa = 10.55AHH1265 pKa = 6.75GFQCRR1270 pKa = 11.84VSYY1273 pKa = 10.11TPEE1276 pKa = 4.26DD1277 pKa = 3.5LGKK1280 pKa = 9.95HH1281 pKa = 4.82VDD1283 pKa = 3.75YY1284 pKa = 9.7CTVGYY1289 pKa = 10.27NEE1291 pKa = 3.9WCKK1294 pKa = 10.45AVCRR1298 pKa = 11.84LGQIYY1303 pKa = 10.07DD1304 pKa = 3.32YY1305 pKa = 10.92SITHH1309 pKa = 6.31NCTDD1313 pKa = 4.58FVQEE1317 pKa = 3.83ITSYY1321 pKa = 10.1QHH1323 pKa = 6.52SFQNTGYY1330 pKa = 8.67WLAAGVVAAAVATTAIFHH1348 pKa = 6.06SVPPSWDD1355 pKa = 3.15EE1356 pKa = 4.53RR1357 pKa = 11.84PFLPEE1362 pKa = 3.23KK1363 pKa = 6.09TTPRR1367 pKa = 11.84VVVVPPRR1374 pKa = 11.84CRR1376 pKa = 11.84VHH1378 pKa = 6.11RR1379 pKa = 11.84WRR1381 pKa = 11.84RR1382 pKa = 11.84ATLEE1386 pKa = 4.18KK1387 pKa = 10.03IIEE1390 pKa = 4.58LKK1392 pKa = 10.68RR1393 pKa = 11.84KK1394 pKa = 8.51MLFQAPINIQLTNPAVDD1411 pKa = 3.59RR1412 pKa = 11.84AASVTTSATLEE1423 pKa = 4.13TLDD1426 pKa = 3.91EE1427 pKa = 4.36VRR1429 pKa = 11.84NMVPVLVNSASTVASSLSAASASVEE1454 pKa = 4.0HH1455 pKa = 6.28LTKK1458 pKa = 10.91SMEE1461 pKa = 4.3TFLEE1465 pKa = 4.43NATSAIPGAVSAMEE1479 pKa = 4.11STAGEE1484 pKa = 4.64LISSASKK1491 pKa = 10.32KK1492 pKa = 9.37VASIILKK1499 pKa = 10.35VIGFTLVIFGNPSPSTIAGVIALLVAEE1526 pKa = 5.05VYY1528 pKa = 11.09DD1529 pKa = 3.75NAYY1532 pKa = 10.22LRR1534 pKa = 11.84KK1535 pKa = 9.92KK1536 pKa = 10.21MSDD1539 pKa = 3.14LAVSFTSKK1547 pKa = 10.41IKK1549 pKa = 10.85DD1550 pKa = 3.47LVGSLFGVSSCCDD1563 pKa = 3.42EE1564 pKa = 4.44EE1565 pKa = 5.82PIFTDD1570 pKa = 3.52IDD1572 pKa = 4.1DD1573 pKa = 4.09AFHH1576 pKa = 7.48RR1577 pKa = 11.84YY1578 pKa = 7.99MLTRR1582 pKa = 11.84TEE1584 pKa = 4.0TDD1586 pKa = 3.87FEE1588 pKa = 4.32FQAPSRR1594 pKa = 11.84LQEE1597 pKa = 3.97FNQGVLAMKK1606 pKa = 9.93NVEE1609 pKa = 4.2WIIEE1613 pKa = 4.29KK1614 pKa = 10.27IKK1616 pKa = 10.75EE1617 pKa = 4.27LIDD1620 pKa = 3.26WLISKK1625 pKa = 9.63LRR1627 pKa = 11.84SKK1629 pKa = 10.4EE1630 pKa = 3.73RR1631 pKa = 11.84SSPEE1635 pKa = 4.17DD1636 pKa = 3.5YY1637 pKa = 11.06LKK1639 pKa = 10.1TRR1641 pKa = 11.84ADD1643 pKa = 4.38YY1644 pKa = 9.05ITDD1647 pKa = 4.34LYY1649 pKa = 10.95RR1650 pKa = 11.84DD1651 pKa = 3.72SLATASCQNVDD1662 pKa = 3.96VNLLNQRR1669 pKa = 11.84VRR1671 pKa = 11.84DD1672 pKa = 3.99TRR1674 pKa = 11.84DD1675 pKa = 2.87MLAYY1679 pKa = 7.96CTNHH1683 pKa = 6.57RR1684 pKa = 11.84LAGAAHH1690 pKa = 6.76ILSRR1694 pKa = 11.84TLANYY1699 pKa = 7.43EE1700 pKa = 3.84QTSRR1704 pKa = 11.84KK1705 pKa = 9.6LKK1707 pKa = 8.69TSTYY1711 pKa = 9.7SSRR1714 pKa = 11.84PEE1716 pKa = 3.59PLVIYY1721 pKa = 10.09IHH1723 pKa = 6.74GSPGVGKK1730 pKa = 10.36SLLSNIIASAYY1741 pKa = 9.64CKK1743 pKa = 10.39RR1744 pKa = 11.84KK1745 pKa = 10.5GIDD1748 pKa = 3.18FKK1750 pKa = 11.02TSVFAQPPGSEE1761 pKa = 4.13YY1762 pKa = 10.59FDD1764 pKa = 5.28GYY1766 pKa = 9.19TGQPVHH1772 pKa = 7.4VIDD1775 pKa = 5.87DD1776 pKa = 4.51FCQNTTGEE1784 pKa = 4.26DD1785 pKa = 3.2VKK1787 pKa = 10.86LFCQMVSTTPFVPPMAALEE1806 pKa = 4.3EE1807 pKa = 4.48KK1808 pKa = 10.16GVQYY1812 pKa = 10.67RR1813 pKa = 11.84SRR1815 pKa = 11.84LILATSNMATPQSNEE1830 pKa = 2.99IRR1832 pKa = 11.84IPGALEE1838 pKa = 3.74RR1839 pKa = 11.84RR1840 pKa = 11.84CHH1842 pKa = 5.37IKK1844 pKa = 10.25VRR1846 pKa = 11.84AILARR1851 pKa = 11.84AFQTPAGRR1859 pKa = 11.84LDD1861 pKa = 3.17MAEE1864 pKa = 4.19AFKK1867 pKa = 10.94EE1868 pKa = 3.87LGPAKK1873 pKa = 10.71SPDD1876 pKa = 3.4FKK1878 pKa = 11.44ADD1880 pKa = 3.39CPYY1883 pKa = 11.37LNGAAMTLSVTKK1895 pKa = 10.96GEE1897 pKa = 4.21DD1898 pKa = 2.82RR1899 pKa = 11.84TRR1901 pKa = 11.84EE1902 pKa = 3.99HH1903 pKa = 6.36MSVYY1907 pKa = 10.19DD1908 pKa = 4.04LCDD1911 pKa = 3.54MIFDD1915 pKa = 4.47EE1916 pKa = 5.72LDD1918 pKa = 3.41EE1919 pKa = 5.74RR1920 pKa = 11.84DD1921 pKa = 3.82GNQTAFSKK1929 pKa = 10.6IIFQAPSQNVISFCKK1944 pKa = 10.14HH1945 pKa = 6.18ADD1947 pKa = 3.43HH1948 pKa = 7.39SPDD1951 pKa = 2.66SCYY1954 pKa = 11.03NIFIATPQGPIVHH1967 pKa = 6.86RR1968 pKa = 11.84FDD1970 pKa = 3.77SVEE1973 pKa = 4.6DD1974 pKa = 3.88RR1975 pKa = 11.84NSWLQSQIPSLPKK1988 pKa = 10.06AGNVRR1993 pKa = 11.84CCPCKK1998 pKa = 10.86NPDD2001 pKa = 3.41CAKK2004 pKa = 10.23IQFTFKK2010 pKa = 10.53TDD2012 pKa = 3.39DD2013 pKa = 3.43EE2014 pKa = 4.64QIRR2017 pKa = 11.84SQVINFPGRR2026 pKa = 11.84DD2027 pKa = 3.37VAEE2030 pKa = 3.52WWLRR2034 pKa = 11.84FVCGRR2039 pKa = 11.84PGSQYY2044 pKa = 11.51ALEE2047 pKa = 4.25SEE2049 pKa = 4.59IWPAPPIFIPTAQPIKK2065 pKa = 10.65NEE2067 pKa = 4.3SIEE2070 pKa = 4.28KK2071 pKa = 9.8EE2072 pKa = 4.06LKK2074 pKa = 10.2KK2075 pKa = 10.38LQKK2078 pKa = 10.1RR2079 pKa = 11.84SLISFTITGISAIASAIGLLIYY2101 pKa = 9.31FLRR2104 pKa = 11.84RR2105 pKa = 11.84RR2106 pKa = 11.84RR2107 pKa = 11.84DD2108 pKa = 3.56PEE2110 pKa = 3.66PQAPYY2115 pKa = 10.2SGAGGRR2121 pKa = 11.84QRR2123 pKa = 11.84QPPQQRR2129 pKa = 11.84PVPQRR2134 pKa = 11.84IVHH2137 pKa = 5.02YY2138 pKa = 8.01QAPYY2142 pKa = 10.86RR2143 pKa = 11.84MPQIYY2148 pKa = 9.3PKK2150 pKa = 10.45VEE2152 pKa = 4.18KK2153 pKa = 10.11NCTSITFHH2161 pKa = 6.52QDD2163 pKa = 2.11SHH2165 pKa = 8.46SFDD2168 pKa = 3.28LTALFICGRR2177 pKa = 11.84TFVCNNHH2184 pKa = 6.02AFSRR2188 pKa = 11.84SHH2190 pKa = 6.26TIEE2193 pKa = 4.29IGGQKK2198 pKa = 10.02YY2199 pKa = 9.43KK2200 pKa = 10.68PEE2202 pKa = 4.11EE2203 pKa = 4.19LSPEE2207 pKa = 4.17LLVRR2211 pKa = 11.84PSGVTDD2217 pKa = 3.37VVICTLPRR2225 pKa = 11.84GDD2227 pKa = 3.46EE2228 pKa = 4.16RR2229 pKa = 11.84KK2230 pKa = 10.29NLVPYY2235 pKa = 10.64LLSQKK2240 pKa = 10.27DD2241 pKa = 3.58RR2242 pKa = 11.84PTNDD2246 pKa = 3.23DD2247 pKa = 3.07VLMVSRR2253 pKa = 11.84SKK2255 pKa = 9.91TIAANFEE2262 pKa = 4.36CTNLRR2267 pKa = 11.84GRR2269 pKa = 11.84KK2270 pKa = 8.4SVCVKK2275 pKa = 10.16EE2276 pKa = 4.44FEE2278 pKa = 4.78NADD2281 pKa = 3.36EE2282 pKa = 4.53QNFHH2286 pKa = 6.85RR2287 pKa = 11.84CYY2289 pKa = 10.38TYY2291 pKa = 10.99DD2292 pKa = 3.59LKK2294 pKa = 10.65STPGMCGAALISRR2307 pKa = 11.84NPARR2311 pKa = 11.84EE2312 pKa = 3.94TLLGIHH2318 pKa = 6.45FAGGPGVGIGVPLYY2332 pKa = 10.84KK2333 pKa = 10.28EE2334 pKa = 4.67DD2335 pKa = 4.22FAHH2338 pKa = 7.63LFQGNLKK2345 pKa = 9.8PIEE2348 pKa = 4.67HH2349 pKa = 7.5PGQPNHH2355 pKa = 6.34IPRR2358 pKa = 11.84RR2359 pKa = 11.84SALKK2363 pKa = 10.25KK2364 pKa = 9.83SPAYY2368 pKa = 10.12GAFPVKK2374 pKa = 10.38SEE2376 pKa = 4.08PAILSQKK2383 pKa = 10.52DD2384 pKa = 3.23KK2385 pKa = 10.89RR2386 pKa = 11.84CEE2388 pKa = 3.75VDD2390 pKa = 3.06LDD2392 pKa = 3.41EE2393 pKa = 5.75VMFSKK2398 pKa = 10.55HH2399 pKa = 5.62VPDD2402 pKa = 3.91HH2403 pKa = 6.44EE2404 pKa = 4.52GWPTLEE2410 pKa = 3.91PAMAYY2415 pKa = 9.87VVEE2418 pKa = 5.05EE2419 pKa = 4.23LMQKK2423 pKa = 10.43CGFSKK2428 pKa = 10.73DD2429 pKa = 3.99DD2430 pKa = 4.36PVPMWTLEE2438 pKa = 3.74QAINGDD2444 pKa = 3.64GVMEE2448 pKa = 5.27GIDD2451 pKa = 3.55MGQSAGYY2458 pKa = 8.65PFSAQGRR2465 pKa = 11.84SRR2467 pKa = 11.84RR2468 pKa = 11.84SFFEE2472 pKa = 3.83WNGEE2476 pKa = 3.43KK2477 pKa = 9.48WQATEE2482 pKa = 3.97EE2483 pKa = 4.1LKK2485 pKa = 11.14KK2486 pKa = 10.99LVDD2489 pKa = 3.93HH2490 pKa = 7.26ALQHH2494 pKa = 6.63PDD2496 pKa = 3.11DD2497 pKa = 4.37YY2498 pKa = 11.85YY2499 pKa = 11.59YY2500 pKa = 10.82ATFLKK2505 pKa = 10.88DD2506 pKa = 3.28EE2507 pKa = 4.7LRR2509 pKa = 11.84PSEE2512 pKa = 4.18KK2513 pKa = 10.55VKK2515 pKa = 10.76AGKK2518 pKa = 7.86TRR2520 pKa = 11.84LVDD2523 pKa = 3.52SDD2525 pKa = 3.96SLPRR2529 pKa = 11.84ILAMRR2534 pKa = 11.84MVFGPLFEE2542 pKa = 6.13AMLRR2546 pKa = 11.84KK2547 pKa = 9.89NGSEE2551 pKa = 3.39IHH2553 pKa = 6.33SAVGCNPDD2561 pKa = 3.34VDD2563 pKa = 3.58WTRR2566 pKa = 11.84FYY2568 pKa = 11.68YY2569 pKa = 10.65EE2570 pKa = 4.53MGPDD2574 pKa = 3.48SFPYY2578 pKa = 10.59CFDD2581 pKa = 4.26LDD2583 pKa = 4.02YY2584 pKa = 11.66SCFDD2588 pKa = 3.17SSEE2591 pKa = 4.01PKK2593 pKa = 10.08IAFLLMAKK2601 pKa = 10.1YY2602 pKa = 10.32LEE2604 pKa = 5.34PYY2606 pKa = 8.57FQHH2609 pKa = 7.38DD2610 pKa = 3.69VTPFLSAVATSKK2622 pKa = 10.65HH2623 pKa = 5.08VYY2625 pKa = 9.52GDD2627 pKa = 3.14KK2628 pKa = 10.44AYY2630 pKa = 9.93EE2631 pKa = 4.16MEE2633 pKa = 5.33GGMPSGCVGTSMFNCINNSAFIVSALIALKK2663 pKa = 10.36ISPDD2667 pKa = 3.21SCKK2670 pKa = 9.97WICYY2674 pKa = 9.3GDD2676 pKa = 4.12DD2677 pKa = 3.86VIISTDD2683 pKa = 3.09EE2684 pKa = 3.87KK2685 pKa = 10.94ALSRR2689 pKa = 11.84RR2690 pKa = 11.84IADD2693 pKa = 4.48FYY2695 pKa = 11.71SRR2697 pKa = 11.84NTNLKK2702 pKa = 8.02VTPACKK2708 pKa = 10.35SGDD2711 pKa = 3.66FPEE2714 pKa = 4.95EE2715 pKa = 3.89STFYY2719 pKa = 10.54EE2720 pKa = 4.32VSFLKK2725 pKa = 10.63RR2726 pKa = 11.84FFVHH2730 pKa = 7.39DD2731 pKa = 3.36SHH2733 pKa = 7.76YY2734 pKa = 10.06PQLIHH2739 pKa = 7.34PYY2741 pKa = 8.84MPLEE2745 pKa = 4.21HH2746 pKa = 7.06LEE2748 pKa = 4.03QSSMWQTDD2756 pKa = 3.26GEE2758 pKa = 4.47YY2759 pKa = 9.85QQKK2762 pKa = 10.5LDD2764 pKa = 4.33SLAQLAFHH2772 pKa = 7.27AGGPDD2777 pKa = 3.22YY2778 pKa = 11.14RR2779 pKa = 11.84KK2780 pKa = 10.18FCDD2783 pKa = 3.52TIQRR2787 pKa = 11.84RR2788 pKa = 11.84CRR2790 pKa = 11.84SRR2792 pKa = 11.84GTEE2795 pKa = 3.92VYY2797 pKa = 9.93FRR2799 pKa = 11.84PFEE2802 pKa = 4.08YY2803 pKa = 11.04YY2804 pKa = 8.38MAMWYY2809 pKa = 10.5AHH2811 pKa = 6.33FMM2813 pKa = 4.24

Molecular weight:
314.2 kDa
Isoelectric point according different methods:






Protein with the highest isoelectric point:
>tr|E9L812|E9L812_MEGR1 Capsid protein VP0 OS=Megrivirus A (isolate Turkey/USA/124/2008) OX=980964 PE=4 SV=1
MM1 pKa = 7.57SYY3 pKa = 10.53KK4 pKa = 10.56PEE6 pKa = 4.8DD7 pKa = 3.65NAPLQSQQEE16 pKa = 4.22DD17 pKa = 3.86KK18 pKa = 11.01APSVAPHH25 pKa = 6.44EE26 pKa = 4.49KK27 pKa = 9.57ATVEE31 pKa = 4.2TTVAAVVQSEE41 pKa = 4.03QDD43 pKa = 3.77VIFDD47 pKa = 3.97NSWTDD52 pKa = 2.99VRR54 pKa = 11.84TIDD57 pKa = 4.31AEE59 pKa = 3.96IPRR62 pKa = 11.84IVATYY67 pKa = 10.27SWTSTQASGDD77 pKa = 3.65FLTAVTGSDD86 pKa = 3.3AVEE89 pKa = 4.26TLPSSPNPFCLPNYY103 pKa = 10.07LIVNQPASSSGLNVPAQVGLFQALFTRR130 pKa = 11.84HH131 pKa = 5.39ALYY134 pKa = 10.48RR135 pKa = 11.84SGFRR139 pKa = 11.84VEE141 pKa = 3.97VTVNGTQFHH150 pKa = 6.45GGSLFVVAIPHH161 pKa = 5.39PHH163 pKa = 5.59VWMQSLTNTDD173 pKa = 3.14AGTQKK178 pKa = 10.58KK179 pKa = 6.43WTALEE184 pKa = 3.97LVQVNQLGIFPSARR198 pKa = 11.84LLPRR202 pKa = 11.84NASAVALDD210 pKa = 4.1LPYY213 pKa = 10.78VGPAPQLEE221 pKa = 4.37TAALDD226 pKa = 3.4VMYY229 pKa = 10.47AIAILVEE236 pKa = 4.5TPLSIPTGTAPTLTVVMRR254 pKa = 11.84VGATNAHH261 pKa = 6.33FFAPKK266 pKa = 9.9PYY268 pKa = 8.82QTPQSNLGAFDD279 pKa = 3.89VPLDD283 pKa = 3.86VPAPASLLQGVRR295 pKa = 11.84VNTAQSAFVNTSSGSIAQIEE315 pKa = 4.19RR316 pKa = 11.84RR317 pKa = 11.84SRR319 pKa = 11.84STEE322 pKa = 3.86TTFLPARR329 pKa = 11.84VEE331 pKa = 4.0DD332 pKa = 3.49WRR334 pKa = 11.84SILSRR339 pKa = 11.84PTLMSLVQFTAATTLGTNIFQTNVCPTGTSVTNRR373 pKa = 11.84DD374 pKa = 3.12ATQALPNASIKK385 pKa = 10.33RR386 pKa = 11.84LQGTPYY392 pKa = 10.42LSQLARR398 pKa = 11.84YY399 pKa = 8.09FSQWRR404 pKa = 11.84GSLTYY409 pKa = 9.44TFEE412 pKa = 4.12YY413 pKa = 10.03TGPQVSSGRR422 pKa = 11.84LLIAFLPGRR431 pKa = 11.84VRR433 pKa = 11.84AAKK436 pKa = 9.86SGQGAEE442 pKa = 4.18YY443 pKa = 10.82VEE445 pKa = 4.52TGALLQNFTEE455 pKa = 4.22NLHH458 pKa = 6.41VIWDD462 pKa = 4.36LSNSTSVSITCPYY475 pKa = 10.58AIATPWAPIVINSWQAIPLSGYY497 pKa = 10.76SSGTLVAVVMSPLVTPTVVAPTSTILVHH525 pKa = 6.68LSAGSDD531 pKa = 3.35FEE533 pKa = 4.39MRR535 pKa = 11.84FPAPIPVNTIPMYY548 pKa = 10.81NGIVDD553 pKa = 3.62QGPAVDD559 pKa = 5.44DD560 pKa = 4.24LPQGEE565 pKa = 5.15HH566 pKa = 6.8YY567 pKa = 9.17LTAMDD572 pKa = 4.08TMSLQTFFNQSRR584 pKa = 11.84FYY586 pKa = 11.53GNFSATAGTTASMVTIPLSLISFAPSSNLKK616 pKa = 10.23VPEE619 pKa = 4.11APVRR623 pKa = 11.84MFAGLFTFLRR633 pKa = 11.84ADD635 pKa = 3.35LRR637 pKa = 11.84ITVGIPFQHH646 pKa = 6.12NLIVTYY652 pKa = 10.02RR653 pKa = 11.84PPTATPSTYY662 pKa = 10.56SAAGAGAPDD671 pKa = 3.71SAASLLNGPSVILSTRR687 pKa = 11.84ASNMGVEE694 pKa = 4.52FVIPFSAFASVFQTSWSQANRR715 pKa = 11.84VDD717 pKa = 3.29TRR719 pKa = 11.84YY720 pKa = 10.75NPDD723 pKa = 3.43SNQTNPGDD731 pKa = 3.36MGTIFVASRR740 pKa = 11.84LPSAQLSNVSVFIAFQNAEE759 pKa = 4.18FFVPRR764 pKa = 11.84PFPPLTSTGWDD775 pKa = 3.08GTAPNNLEE783 pKa = 3.89GEE785 pKa = 4.45FWEE788 pKa = 5.1EE789 pKa = 3.47EE790 pKa = 4.11DD791 pKa = 3.5PTPVEE796 pKa = 4.34FQAPTTEE803 pKa = 4.09GLEE806 pKa = 4.29KK807 pKa = 10.47GDD809 pKa = 3.62QVMLSVTLDD818 pKa = 3.06ILDD821 pKa = 4.79SIRR824 pKa = 11.84EE825 pKa = 4.19LCSEE829 pKa = 3.98LMEE832 pKa = 5.21NVDD835 pKa = 3.64TLYY838 pKa = 11.25GRR840 pKa = 11.84ARR842 pKa = 11.84AAKK845 pKa = 9.08FAWLVQSTFEE855 pKa = 3.91EE856 pKa = 4.54WKK858 pKa = 11.07KK859 pKa = 10.85NDD861 pKa = 3.05QDD863 pKa = 3.63ADD865 pKa = 3.75EE866 pKa = 5.02FFSDD870 pKa = 3.58VSLVEE875 pKa = 3.92PVVFQSPPSPSARR888 pKa = 11.84EE889 pKa = 3.37KK890 pKa = 10.57AARR893 pKa = 11.84LEE895 pKa = 4.05EE896 pKa = 4.42FFDD899 pKa = 3.68YY900 pKa = 10.0MYY902 pKa = 11.28GCVEE906 pKa = 4.21SEE908 pKa = 4.41EE909 pKa = 4.24EE910 pKa = 3.89LHH912 pKa = 6.75AVCDD916 pKa = 3.84AVNAVIDD923 pKa = 3.88SFYY926 pKa = 11.24DD927 pKa = 3.23SDD929 pKa = 4.03GDD931 pKa = 4.02FIGEE935 pKa = 3.65IRR937 pKa = 11.84DD938 pKa = 3.64RR939 pKa = 11.84FLEE942 pKa = 4.45LPLSYY947 pKa = 10.73PEE949 pKa = 5.02GPDD952 pKa = 3.23HH953 pKa = 7.1AGVWFRR959 pKa = 11.84GEE961 pKa = 4.6FYY963 pKa = 10.56RR964 pKa = 11.84CLYY967 pKa = 9.19VTTQNRR973 pKa = 11.84FFPQVAAYY981 pKa = 10.22SPVEE985 pKa = 4.09TEE987 pKa = 4.29HH988 pKa = 7.66NLFALYY994 pKa = 9.5EE995 pKa = 3.97ALRR998 pKa = 11.84QFEE1001 pKa = 4.86LMCIADD1007 pKa = 4.13PLSTSHH1013 pKa = 7.15HH1014 pKa = 4.82YY1015 pKa = 10.17QRR1017 pKa = 11.84LLFLLLQQQWVIPEE1031 pKa = 4.05MKK1033 pKa = 10.67SMVRR1037 pKa = 11.84EE1038 pKa = 3.96KK1039 pKa = 10.96LAFLYY1044 pKa = 10.64TMVAHH1049 pKa = 6.94PEE1051 pKa = 4.06RR1052 pKa = 11.84IFLDD1056 pKa = 3.7WNWEE1060 pKa = 4.07LFHH1063 pKa = 6.1TQPFRR1068 pKa = 11.84YY1069 pKa = 7.93ICNMVGVEE1077 pKa = 4.24TALTDD1082 pKa = 3.87DD1083 pKa = 4.74GFFSGDD1089 pKa = 3.32EE1090 pKa = 4.11EE1091 pKa = 4.99GQFQAPTSCDD1101 pKa = 3.2QKK1103 pKa = 11.14FLNLVRR1109 pKa = 11.84AYY1111 pKa = 10.09RR1112 pKa = 11.84DD1113 pKa = 3.37AMIVNPWHH1121 pKa = 5.82TFEE1124 pKa = 3.86VCYY1127 pKa = 10.52ISFYY1131 pKa = 11.47DD1132 pKa = 3.58LTCRR1136 pKa = 11.84SDD1138 pKa = 3.31VPEE1141 pKa = 3.92WFKK1144 pKa = 11.14RR1145 pKa = 11.84AVEE1148 pKa = 4.09DD1149 pKa = 3.58ACFDD1153 pKa = 3.95TLCARR1158 pKa = 11.84VAEE1161 pKa = 4.07RR1162 pKa = 11.84VNVNNEE1168 pKa = 3.74VLIEE1172 pKa = 4.45RR1173 pKa = 11.84YY1174 pKa = 9.1RR1175 pKa = 11.84QLYY1178 pKa = 10.52DD1179 pKa = 3.85EE1180 pKa = 5.2IFSEE1184 pKa = 4.67EE1185 pKa = 4.2PDD1187 pKa = 3.64FFSDD1191 pKa = 4.95DD1192 pKa = 4.03EE1193 pKa = 4.98IDD1195 pKa = 5.36AEE1197 pKa = 4.46FQAPKK1202 pKa = 9.8PPAPASSVPVPRR1214 pKa = 11.84PSTPLPSPATSEE1226 pKa = 4.97DD1227 pKa = 3.73EE1228 pKa = 5.56DD1229 pKa = 3.96EE1230 pKa = 6.38GEE1232 pKa = 5.37DD1233 pKa = 4.17EE1234 pKa = 5.02PDD1236 pKa = 4.97DD1237 pKa = 3.61ICVYY1241 pKa = 10.76YY1242 pKa = 10.68VDD1244 pKa = 3.78NGLYY1248 pKa = 9.71RR1249 pKa = 11.84HH1250 pKa = 5.99WGIRR1254 pKa = 11.84NKK1256 pKa = 9.88QQAISLKK1263 pKa = 10.55AHH1265 pKa = 6.75GFQCRR1270 pKa = 11.84VSYY1273 pKa = 10.11TPEE1276 pKa = 4.26DD1277 pKa = 3.5LGKK1280 pKa = 9.95HH1281 pKa = 4.82VDD1283 pKa = 3.75YY1284 pKa = 9.7CTVGYY1289 pKa = 10.27NEE1291 pKa = 3.9WCKK1294 pKa = 10.45AVCRR1298 pKa = 11.84LGQIYY1303 pKa = 10.07DD1304 pKa = 3.32YY1305 pKa = 10.92SITHH1309 pKa = 6.31NCTDD1313 pKa = 4.58FVQEE1317 pKa = 3.83ITSYY1321 pKa = 10.1QHH1323 pKa = 6.52SFQNTGYY1330 pKa = 8.67WLAAGVVAAAVATTAIFHH1348 pKa = 6.06SVPPSWDD1355 pKa = 3.15EE1356 pKa = 4.53RR1357 pKa = 11.84PFLPEE1362 pKa = 3.23KK1363 pKa = 6.09TTPRR1367 pKa = 11.84VVVVPPRR1374 pKa = 11.84CRR1376 pKa = 11.84VHH1378 pKa = 6.11RR1379 pKa = 11.84WRR1381 pKa = 11.84RR1382 pKa = 11.84ATLEE1386 pKa = 4.18KK1387 pKa = 10.03IIEE1390 pKa = 4.58LKK1392 pKa = 10.68RR1393 pKa = 11.84KK1394 pKa = 8.51MLFQAPINIQLTNPAVDD1411 pKa = 3.59RR1412 pKa = 11.84AASVTTSATLEE1423 pKa = 4.13TLDD1426 pKa = 3.91EE1427 pKa = 4.36VRR1429 pKa = 11.84NMVPVLVNSASTVASSLSAASASVEE1454 pKa = 4.0HH1455 pKa = 6.28LTKK1458 pKa = 10.91SMEE1461 pKa = 4.3TFLEE1465 pKa = 4.43NATSAIPGAVSAMEE1479 pKa = 4.11STAGEE1484 pKa = 4.64LISSASKK1491 pKa = 10.32KK1492 pKa = 9.37VASIILKK1499 pKa = 10.35VIGFTLVIFGNPSPSTIAGVIALLVAEE1526 pKa = 5.05VYY1528 pKa = 11.09DD1529 pKa = 3.75NAYY1532 pKa = 10.22LRR1534 pKa = 11.84KK1535 pKa = 9.92KK1536 pKa = 10.21MSDD1539 pKa = 3.14LAVSFTSKK1547 pKa = 10.41IKK1549 pKa = 10.85DD1550 pKa = 3.47LVGSLFGVSSCCDD1563 pKa = 3.42EE1564 pKa = 4.44EE1565 pKa = 5.82PIFTDD1570 pKa = 3.52IDD1572 pKa = 4.1DD1573 pKa = 4.09AFHH1576 pKa = 7.48RR1577 pKa = 11.84YY1578 pKa = 7.99MLTRR1582 pKa = 11.84TEE1584 pKa = 4.0TDD1586 pKa = 3.87FEE1588 pKa = 4.32FQAPSRR1594 pKa = 11.84LQEE1597 pKa = 3.97FNQGVLAMKK1606 pKa = 9.93NVEE1609 pKa = 4.2WIIEE1613 pKa = 4.29KK1614 pKa = 10.27IKK1616 pKa = 10.75EE1617 pKa = 4.27LIDD1620 pKa = 3.26WLISKK1625 pKa = 9.63LRR1627 pKa = 11.84SKK1629 pKa = 10.4EE1630 pKa = 3.73RR1631 pKa = 11.84SSPEE1635 pKa = 4.17DD1636 pKa = 3.5YY1637 pKa = 11.06LKK1639 pKa = 10.1TRR1641 pKa = 11.84ADD1643 pKa = 4.38YY1644 pKa = 9.05ITDD1647 pKa = 4.34LYY1649 pKa = 10.95RR1650 pKa = 11.84DD1651 pKa = 3.72SLATASCQNVDD1662 pKa = 3.96VNLLNQRR1669 pKa = 11.84VRR1671 pKa = 11.84DD1672 pKa = 3.99TRR1674 pKa = 11.84DD1675 pKa = 2.87MLAYY1679 pKa = 7.96CTNHH1683 pKa = 6.57RR1684 pKa = 11.84LAGAAHH1690 pKa = 6.76ILSRR1694 pKa = 11.84TLANYY1699 pKa = 7.43EE1700 pKa = 3.84QTSRR1704 pKa = 11.84KK1705 pKa = 9.6LKK1707 pKa = 8.69TSTYY1711 pKa = 9.7SSRR1714 pKa = 11.84PEE1716 pKa = 3.59PLVIYY1721 pKa = 10.09IHH1723 pKa = 6.74GSPGVGKK1730 pKa = 10.36SLLSNIIASAYY1741 pKa = 9.64CKK1743 pKa = 10.39RR1744 pKa = 11.84KK1745 pKa = 10.5GIDD1748 pKa = 3.18FKK1750 pKa = 11.02TSVFAQPPGSEE1761 pKa = 4.13YY1762 pKa = 10.59FDD1764 pKa = 5.28GYY1766 pKa = 9.19TGQPVHH1772 pKa = 7.4VIDD1775 pKa = 5.87DD1776 pKa = 4.51FCQNTTGEE1784 pKa = 4.26DD1785 pKa = 3.2VKK1787 pKa = 10.86LFCQMVSTTPFVPPMAALEE1806 pKa = 4.3EE1807 pKa = 4.48KK1808 pKa = 10.16GVQYY1812 pKa = 10.67RR1813 pKa = 11.84SRR1815 pKa = 11.84LILATSNMATPQSNEE1830 pKa = 2.99IRR1832 pKa = 11.84IPGALEE1838 pKa = 3.74RR1839 pKa = 11.84RR1840 pKa = 11.84CHH1842 pKa = 5.37IKK1844 pKa = 10.25VRR1846 pKa = 11.84AILARR1851 pKa = 11.84AFQTPAGRR1859 pKa = 11.84LDD1861 pKa = 3.17MAEE1864 pKa = 4.19AFKK1867 pKa = 10.94EE1868 pKa = 3.87LGPAKK1873 pKa = 10.71SPDD1876 pKa = 3.4FKK1878 pKa = 11.44ADD1880 pKa = 3.39CPYY1883 pKa = 11.37LNGAAMTLSVTKK1895 pKa = 10.96GEE1897 pKa = 4.21DD1898 pKa = 2.82RR1899 pKa = 11.84TRR1901 pKa = 11.84EE1902 pKa = 3.99HH1903 pKa = 6.36MSVYY1907 pKa = 10.19DD1908 pKa = 4.04LCDD1911 pKa = 3.54MIFDD1915 pKa = 4.47EE1916 pKa = 5.72LDD1918 pKa = 3.41EE1919 pKa = 5.74RR1920 pKa = 11.84DD1921 pKa = 3.82GNQTAFSKK1929 pKa = 10.6IIFQAPSQNVISFCKK1944 pKa = 10.14HH1945 pKa = 6.18ADD1947 pKa = 3.43HH1948 pKa = 7.39SPDD1951 pKa = 2.66SCYY1954 pKa = 11.03NIFIATPQGPIVHH1967 pKa = 6.86RR1968 pKa = 11.84FDD1970 pKa = 3.77SVEE1973 pKa = 4.6DD1974 pKa = 3.88RR1975 pKa = 11.84NSWLQSQIPSLPKK1988 pKa = 10.06AGNVRR1993 pKa = 11.84CCPCKK1998 pKa = 10.86NPDD2001 pKa = 3.41CAKK2004 pKa = 10.23IQFTFKK2010 pKa = 10.53TDD2012 pKa = 3.39DD2013 pKa = 3.43EE2014 pKa = 4.64QIRR2017 pKa = 11.84SQVINFPGRR2026 pKa = 11.84DD2027 pKa = 3.37VAEE2030 pKa = 3.52WWLRR2034 pKa = 11.84FVCGRR2039 pKa = 11.84PGSQYY2044 pKa = 11.51ALEE2047 pKa = 4.25SEE2049 pKa = 4.59IWPAPPIFIPTAQPIKK2065 pKa = 10.65NEE2067 pKa = 4.3SIEE2070 pKa = 4.28KK2071 pKa = 9.8EE2072 pKa = 4.06LKK2074 pKa = 10.2KK2075 pKa = 10.38LQKK2078 pKa = 10.1RR2079 pKa = 11.84SLISFTITGISAIASAIGLLIYY2101 pKa = 9.31FLRR2104 pKa = 11.84RR2105 pKa = 11.84RR2106 pKa = 11.84RR2107 pKa = 11.84DD2108 pKa = 3.56PEE2110 pKa = 3.66PQAPYY2115 pKa = 10.2SGAGGRR2121 pKa = 11.84QRR2123 pKa = 11.84QPPQQRR2129 pKa = 11.84PVPQRR2134 pKa = 11.84IVHH2137 pKa = 5.02YY2138 pKa = 8.01QAPYY2142 pKa = 10.86RR2143 pKa = 11.84MPQIYY2148 pKa = 9.3PKK2150 pKa = 10.45VEE2152 pKa = 4.18KK2153 pKa = 10.11NCTSITFHH2161 pKa = 6.52QDD2163 pKa = 2.11SHH2165 pKa = 8.46SFDD2168 pKa = 3.28LTALFICGRR2177 pKa = 11.84TFVCNNHH2184 pKa = 6.02AFSRR2188 pKa = 11.84SHH2190 pKa = 6.26TIEE2193 pKa = 4.29IGGQKK2198 pKa = 10.02YY2199 pKa = 9.43KK2200 pKa = 10.68PEE2202 pKa = 4.11EE2203 pKa = 4.19LSPEE2207 pKa = 4.17LLVRR2211 pKa = 11.84PSGVTDD2217 pKa = 3.37VVICTLPRR2225 pKa = 11.84GDD2227 pKa = 3.46EE2228 pKa = 4.16RR2229 pKa = 11.84KK2230 pKa = 10.29NLVPYY2235 pKa = 10.64LLSQKK2240 pKa = 10.27DD2241 pKa = 3.58RR2242 pKa = 11.84PTNDD2246 pKa = 3.23DD2247 pKa = 3.07VLMVSRR2253 pKa = 11.84SKK2255 pKa = 9.91TIAANFEE2262 pKa = 4.36CTNLRR2267 pKa = 11.84GRR2269 pKa = 11.84KK2270 pKa = 8.4SVCVKK2275 pKa = 10.16EE2276 pKa = 4.44FEE2278 pKa = 4.78NADD2281 pKa = 3.36EE2282 pKa = 4.53QNFHH2286 pKa = 6.85RR2287 pKa = 11.84CYY2289 pKa = 10.38TYY2291 pKa = 10.99DD2292 pKa = 3.59LKK2294 pKa = 10.65STPGMCGAALISRR2307 pKa = 11.84NPARR2311 pKa = 11.84EE2312 pKa = 3.94TLLGIHH2318 pKa = 6.45FAGGPGVGIGVPLYY2332 pKa = 10.84KK2333 pKa = 10.28EE2334 pKa = 4.67DD2335 pKa = 4.22FAHH2338 pKa = 7.63LFQGNLKK2345 pKa = 9.8PIEE2348 pKa = 4.67HH2349 pKa = 7.5PGQPNHH2355 pKa = 6.34IPRR2358 pKa = 11.84RR2359 pKa = 11.84SALKK2363 pKa = 10.25KK2364 pKa = 9.83SPAYY2368 pKa = 10.12GAFPVKK2374 pKa = 10.38SEE2376 pKa = 4.08PAILSQKK2383 pKa = 10.52DD2384 pKa = 3.23KK2385 pKa = 10.89RR2386 pKa = 11.84CEE2388 pKa = 3.75VDD2390 pKa = 3.06LDD2392 pKa = 3.41EE2393 pKa = 5.75VMFSKK2398 pKa = 10.55HH2399 pKa = 5.62VPDD2402 pKa = 3.91HH2403 pKa = 6.44EE2404 pKa = 4.52GWPTLEE2410 pKa = 3.91PAMAYY2415 pKa = 9.87VVEE2418 pKa = 5.05EE2419 pKa = 4.23LMQKK2423 pKa = 10.43CGFSKK2428 pKa = 10.73DD2429 pKa = 3.99DD2430 pKa = 4.36PVPMWTLEE2438 pKa = 3.74QAINGDD2444 pKa = 3.64GVMEE2448 pKa = 5.27GIDD2451 pKa = 3.55MGQSAGYY2458 pKa = 8.65PFSAQGRR2465 pKa = 11.84SRR2467 pKa = 11.84RR2468 pKa = 11.84SFFEE2472 pKa = 3.83WNGEE2476 pKa = 3.43KK2477 pKa = 9.48WQATEE2482 pKa = 3.97EE2483 pKa = 4.1LKK2485 pKa = 11.14KK2486 pKa = 10.99LVDD2489 pKa = 3.93HH2490 pKa = 7.26ALQHH2494 pKa = 6.63PDD2496 pKa = 3.11DD2497 pKa = 4.37YY2498 pKa = 11.85YY2499 pKa = 11.59YY2500 pKa = 10.82ATFLKK2505 pKa = 10.88DD2506 pKa = 3.28EE2507 pKa = 4.7LRR2509 pKa = 11.84PSEE2512 pKa = 4.18KK2513 pKa = 10.55VKK2515 pKa = 10.76AGKK2518 pKa = 7.86TRR2520 pKa = 11.84LVDD2523 pKa = 3.52SDD2525 pKa = 3.96SLPRR2529 pKa = 11.84ILAMRR2534 pKa = 11.84MVFGPLFEE2542 pKa = 6.13AMLRR2546 pKa = 11.84KK2547 pKa = 9.89NGSEE2551 pKa = 3.39IHH2553 pKa = 6.33SAVGCNPDD2561 pKa = 3.34VDD2563 pKa = 3.58WTRR2566 pKa = 11.84FYY2568 pKa = 11.68YY2569 pKa = 10.65EE2570 pKa = 4.53MGPDD2574 pKa = 3.48SFPYY2578 pKa = 10.59CFDD2581 pKa = 4.26LDD2583 pKa = 4.02YY2584 pKa = 11.66SCFDD2588 pKa = 3.17SSEE2591 pKa = 4.01PKK2593 pKa = 10.08IAFLLMAKK2601 pKa = 10.1YY2602 pKa = 10.32LEE2604 pKa = 5.34PYY2606 pKa = 8.57FQHH2609 pKa = 7.38DD2610 pKa = 3.69VTPFLSAVATSKK2622 pKa = 10.65HH2623 pKa = 5.08VYY2625 pKa = 9.52GDD2627 pKa = 3.14KK2628 pKa = 10.44AYY2630 pKa = 9.93EE2631 pKa = 4.16MEE2633 pKa = 5.33GGMPSGCVGTSMFNCINNSAFIVSALIALKK2663 pKa = 10.36ISPDD2667 pKa = 3.21SCKK2670 pKa = 9.97WICYY2674 pKa = 9.3GDD2676 pKa = 4.12DD2677 pKa = 3.86VIISTDD2683 pKa = 3.09EE2684 pKa = 3.87KK2685 pKa = 10.94ALSRR2689 pKa = 11.84RR2690 pKa = 11.84IADD2693 pKa = 4.48FYY2695 pKa = 11.71SRR2697 pKa = 11.84NTNLKK2702 pKa = 8.02VTPACKK2708 pKa = 10.35SGDD2711 pKa = 3.66FPEE2714 pKa = 4.95EE2715 pKa = 3.89STFYY2719 pKa = 10.54EE2720 pKa = 4.32VSFLKK2725 pKa = 10.63RR2726 pKa = 11.84FFVHH2730 pKa = 7.39DD2731 pKa = 3.36SHH2733 pKa = 7.76YY2734 pKa = 10.06PQLIHH2739 pKa = 7.34PYY2741 pKa = 8.84MPLEE2745 pKa = 4.21HH2746 pKa = 7.06LEE2748 pKa = 4.03QSSMWQTDD2756 pKa = 3.26GEE2758 pKa = 4.47YY2759 pKa = 9.85QQKK2762 pKa = 10.5LDD2764 pKa = 4.33SLAQLAFHH2772 pKa = 7.27AGGPDD2777 pKa = 3.22YY2778 pKa = 11.14RR2779 pKa = 11.84KK2780 pKa = 10.18FCDD2783 pKa = 3.52TIQRR2787 pKa = 11.84RR2788 pKa = 11.84CRR2790 pKa = 11.84SRR2792 pKa = 11.84GTEE2795 pKa = 3.92VYY2797 pKa = 9.93FRR2799 pKa = 11.84PFEE2802 pKa = 4.08YY2803 pKa = 11.04YY2804 pKa = 8.38MAMWYY2809 pKa = 10.5AHH2811 pKa = 6.33FMM2813 pKa = 4.24

Molecular weight:
314.2 kDa
Isoelectric point according different methods:






Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

1

0

1

2813

2813

2813

2813.0

314.2

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

8.354 ± 0.0

2.062 ± 0.0

5.51 ± 0.0

5.972 ± 0.0

5.475 ± 0.0

5.084 ± 0.0

2.097 ± 0.0

4.977 ± 0.0

3.733 ± 0.0

7.785 ± 0.0

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.133 ± 0.0

3.662 ± 0.0

6.968 ± 0.0

4.301 ± 0.0

5.297 ± 0.0

8.176 ± 0.0

6.47 ± 0.0

7.003 ± 0.0

1.386 ± 0.0

3.555 ± 0.0

Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski