Amino acid dipepetide frequency for Fusarium oxysporum NRRL 32931

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.303AlaAla: 8.303 ± 0.055	1.139AlaCys: 1.139 ± 0.012	4.088AlaAsp: 4.088 ± 0.021	4.966AlaGlu: 4.966 ± 0.037	3.104AlaPhe: 3.104 ± 0.019	5.45AlaGly: 5.45 ± 0.03	1.693AlaHis: 1.693 ± 0.013	4.449AlaIle: 4.449 ± 0.024	4.066AlaLys: 4.066 ± 0.026	7.513AlaLeu: 7.513 ± 0.035	2.007AlaMet: 2.007 ± 0.015	2.947AlaAsn: 2.947 ± 0.02	4.621AlaPro: 4.621 ± 0.037	3.32AlaGln: 3.32 ± 0.021	4.503AlaArg: 4.503 ± 0.024	6.982AlaSer: 6.982 ± 0.033	5.177AlaThr: 5.177 ± 0.028	5.145AlaVal: 5.145 ± 0.026	1.193AlaTrp: 1.193 ± 0.011	2.121AlaTyr: 2.121 ± 0.015	0.0AlaXaa: 0.0 ± 0.0
Cys	0.928CysAla: 0.928 ± 0.011	0.283CysCys: 0.283 ± 0.006	0.741CysAsp: 0.741 ± 0.01	0.653CysGlu: 0.653 ± 0.008	0.588CysPhe: 0.588 ± 0.009	0.958CysGly: 0.958 ± 0.013	0.371CysHis: 0.371 ± 0.007	0.802CysIle: 0.802 ± 0.01	0.602CysLys: 0.602 ± 0.011	1.353CysLeu: 1.353 ± 0.015	0.302CysMet: 0.302 ± 0.006	0.494CysAsn: 0.494 ± 0.008	0.686CysPro: 0.686 ± 0.01	0.528CysGln: 0.528 ± 0.009	0.828CysArg: 0.828 ± 0.009	0.983CysSer: 0.983 ± 0.012	0.745CysThr: 0.745 ± 0.01	0.851CysVal: 0.851 ± 0.012	0.229CysTrp: 0.229 ± 0.005	0.398CysTyr: 0.398 ± 0.007	0.0CysXaa: 0.0 ± 0.0
Asp	4.582AspAla: 4.582 ± 0.023	0.685AspCys: 0.685 ± 0.009	4.365AspAsp: 4.365 ± 0.03	4.577AspGlu: 4.577 ± 0.028	2.274AspPhe: 2.274 ± 0.016	4.017AspGly: 4.017 ± 0.021	1.292AspHis: 1.292 ± 0.012	3.227AspIle: 3.227 ± 0.019	2.669AspLys: 2.669 ± 0.02	5.092AspLeu: 5.092 ± 0.026	1.378AspMet: 1.378 ± 0.013	2.051AspAsn: 2.051 ± 0.014	3.284AspPro: 3.284 ± 0.024	1.989AspGln: 1.989 ± 0.016	2.984AspArg: 2.984 ± 0.02	4.185AspSer: 4.185 ± 0.024	3.063AspThr: 3.063 ± 0.019	3.646AspVal: 3.646 ± 0.022	0.918AspTrp: 0.918 ± 0.01	1.623AspTyr: 1.623 ± 0.014	0.0AspXaa: 0.0 ± 0.0
Glu	5.462GluAla: 5.462 ± 0.043	0.678GluCys: 0.678 ± 0.009	4.165GluAsp: 4.165 ± 0.029	5.229GluGlu: 5.229 ± 0.048	1.988GluPhe: 1.988 ± 0.015	3.602GluGly: 3.602 ± 0.02	1.442GluHis: 1.442 ± 0.013	3.081GluIle: 3.081 ± 0.019	3.668GluLys: 3.668 ± 0.026	5.177GluLeu: 5.177 ± 0.025	1.479GluMet: 1.479 ± 0.012	2.371GluAsn: 2.371 ± 0.017	2.984GluPro: 2.984 ± 0.028	2.426GluGln: 2.426 ± 0.019	3.739GluArg: 3.739 ± 0.023	4.334GluSer: 4.334 ± 0.026	3.747GluThr: 3.747 ± 0.028	3.568GluVal: 3.568 ± 0.022	0.896GluTrp: 0.896 ± 0.009	1.673GluTyr: 1.673 ± 0.014	0.0GluXaa: 0.0 ± 0.0
Phe	2.983PheAla: 2.983 ± 0.018	0.626PheCys: 0.626 ± 0.009	2.361PheAsp: 2.361 ± 0.016	2.192PheGlu: 2.192 ± 0.014	1.692PhePhe: 1.692 ± 0.017	2.887PheGly: 2.887 ± 0.021	0.929PheHis: 0.929 ± 0.01	1.986PheIle: 1.986 ± 0.016	1.648PheLys: 1.648 ± 0.015	3.513PheLeu: 3.513 ± 0.022	0.852PheMet: 0.852 ± 0.01	1.55PheAsn: 1.55 ± 0.013	1.928PhePro: 1.928 ± 0.015	1.45PheGln: 1.45 ± 0.013	1.941PheArg: 1.941 ± 0.017	3.034PheSer: 3.034 ± 0.018	2.245PheThr: 2.245 ± 0.017	2.426PheVal: 2.426 ± 0.019	0.696PheTrp: 0.696 ± 0.009	1.133PheTyr: 1.133 ± 0.011	0.0PheXaa: 0.0 ± 0.0
Gly	4.987GlyAla: 4.987 ± 0.028	0.909GlyCys: 0.909 ± 0.01	3.68GlyAsp: 3.68 ± 0.02	3.474GlyGlu: 3.474 ± 0.023	2.827GlyPhe: 2.827 ± 0.017	5.327GlyGly: 5.327 ± 0.048	1.709GlyHis: 1.709 ± 0.013	3.626GlyIle: 3.626 ± 0.021	3.37GlyLys: 3.37 ± 0.021	6.047GlyLeu: 6.047 ± 0.03	1.603GlyMet: 1.603 ± 0.015	2.679GlyAsn: 2.679 ± 0.02	3.308GlyPro: 3.308 ± 0.024	2.623GlyGln: 2.623 ± 0.02	3.944GlyArg: 3.944 ± 0.023	5.666GlySer: 5.666 ± 0.032	3.97GlyThr: 3.97 ± 0.036	4.104GlyVal: 4.104 ± 0.024	1.173GlyTrp: 1.173 ± 0.012	2.175GlyTyr: 2.175 ± 0.017	0.0GlyXaa: 0.0 ± 0.0
His	1.74HisAla: 1.74 ± 0.014	0.354HisCys: 0.354 ± 0.006	1.419HisAsp: 1.419 ± 0.014	1.385HisGlu: 1.385 ± 0.012	0.94HisPhe: 0.94 ± 0.01	1.742HisGly: 1.742 ± 0.014	0.886HisHis: 0.886 ± 0.014	1.286HisIle: 1.286 ± 0.012	0.989HisLys: 0.989 ± 0.012	2.272HisLeu: 2.272 ± 0.02	0.538HisMet: 0.538 ± 0.007	0.888HisAsn: 0.888 ± 0.01	1.556HisPro: 1.556 ± 0.014	1.05HisGln: 1.05 ± 0.013	1.509HisArg: 1.509 ± 0.014	1.808HisSer: 1.808 ± 0.016	1.23HisThr: 1.23 ± 0.012	1.434HisVal: 1.434 ± 0.013	0.357HisTrp: 0.357 ± 0.006	0.723HisTyr: 0.723 ± 0.009	0.0HisXaa: 0.0 ± 0.0
Ile	4.255IleAla: 4.255 ± 0.024	0.828IleCys: 0.828 ± 0.012	3.015IleAsp: 3.015 ± 0.019	3.057IleGlu: 3.057 ± 0.023	2.093IlePhe: 2.093 ± 0.016	3.307IleGly: 3.307 ± 0.021	1.259IleHis: 1.259 ± 0.013	2.762IleIle: 2.762 ± 0.023	2.377IleLys: 2.377 ± 0.019	4.689IleLeu: 4.689 ± 0.026	1.144IleMet: 1.144 ± 0.012	1.984IleAsn: 1.984 ± 0.012	3.063IlePro: 3.063 ± 0.02	1.992IleGln: 1.992 ± 0.016	2.853IleArg: 2.853 ± 0.019	4.014IleSer: 4.014 ± 0.022	3.041IleThr: 3.041 ± 0.032	3.243IleVal: 3.243 ± 0.022	0.804IleTrp: 0.804 ± 0.01	1.471IleTyr: 1.471 ± 0.014	0.0IleXaa: 0.0 ± 0.0
Lys	4.336LysAla: 4.336 ± 0.025	0.59LysCys: 0.59 ± 0.01	3.068LysAsp: 3.068 ± 0.025	3.408LysGlu: 3.408 ± 0.026	1.544LysPhe: 1.544 ± 0.015	3.034LysGly: 3.034 ± 0.022	1.185LysHis: 1.185 ± 0.013	2.327LysIle: 2.327 ± 0.018	3.387LysLys: 3.387 ± 0.032	4.2LysLeu: 4.2 ± 0.027	1.058LysMet: 1.058 ± 0.011	1.885LysAsn: 1.885 ± 0.017	2.893LysPro: 2.893 ± 0.022	1.888LysGln: 1.888 ± 0.016	3.288LysArg: 3.288 ± 0.019	3.603LysSer: 3.603 ± 0.025	3.041LysThr: 3.041 ± 0.018	2.88LysVal: 2.88 ± 0.02	0.719LysTrp: 0.719 ± 0.009	1.407LysTyr: 1.407 ± 0.014	0.0LysXaa: 0.0 ± 0.0
Leu	7.574LeuAla: 7.574 ± 0.035	1.302LeuCys: 1.302 ± 0.014	5.205LeuAsp: 5.205 ± 0.03	5.527LeuGlu: 5.527 ± 0.031	3.466LeuPhe: 3.466 ± 0.023	5.847LeuGly: 5.847 ± 0.032	2.204LeuHis: 2.204 ± 0.018	4.201LeuIle: 4.201 ± 0.026	4.257LeuLys: 4.257 ± 0.027	8.175LeuLeu: 8.175 ± 0.048	1.898LeuMet: 1.898 ± 0.015	3.247LeuAsn: 3.247 ± 0.021	5.25LeuPro: 5.25 ± 0.025	3.809LeuGln: 3.809 ± 0.027	5.48LeuArg: 5.48 ± 0.029	7.253LeuSer: 7.253 ± 0.039	4.837LeuThr: 4.837 ± 0.024	5.422LeuVal: 5.422 ± 0.032	1.241LeuTrp: 1.241 ± 0.013	2.362LeuTyr: 2.362 ± 0.016	0.0LeuXaa: 0.0 ± 0.0
Met	2.305MetAla: 2.305 ± 0.014	0.265MetCys: 0.265 ± 0.005	1.293MetAsp: 1.293 ± 0.012	1.286MetGlu: 1.286 ± 0.013	0.805MetPhe: 0.805 ± 0.01	1.485MetGly: 1.485 ± 0.014	0.497MetHis: 0.497 ± 0.007	1.108MetIle: 1.108 ± 0.012	1.091MetLys: 1.091 ± 0.011	1.925MetLeu: 1.925 ± 0.017	0.67MetMet: 0.67 ± 0.009	0.889MetAsn: 0.889 ± 0.011	1.376MetPro: 1.376 ± 0.013	0.888MetGln: 0.888 ± 0.01	1.245MetArg: 1.245 ± 0.011	2.052MetSer: 2.052 ± 0.017	1.41MetThr: 1.41 ± 0.013	1.342MetVal: 1.342 ± 0.012	0.287MetTrp: 0.287 ± 0.006	0.55MetTyr: 0.55 ± 0.008	0.0MetXaa: 0.0 ± 0.0
Asn	3.054AsnAla: 3.054 ± 0.018	0.496AsnCys: 0.496 ± 0.008	2.122AsnAsp: 2.122 ± 0.017	2.139AsnGlu: 2.139 ± 0.015	1.446AsnPhe: 1.446 ± 0.013	3.034AsnGly: 3.034 ± 0.023	0.894AsnHis: 0.894 ± 0.011	2.147AsnIle: 2.147 ± 0.017	1.772AsnLys: 1.772 ± 0.015	3.378AsnLeu: 3.378 ± 0.02	0.956AsnMet: 0.956 ± 0.011	1.652AsnAsn: 1.652 ± 0.016	2.449AsnPro: 2.449 ± 0.02	1.444AsnGln: 1.444 ± 0.014	1.973AsnArg: 1.973 ± 0.016	2.915AsnSer: 2.915 ± 0.019	2.296AsnThr: 2.296 ± 0.017	2.309AsnVal: 2.309 ± 0.022	0.605AsnTrp: 0.605 ± 0.009	1.087AsnTyr: 1.087 ± 0.012	0.0AsnXaa: 0.0 ± 0.0
Pro	4.864ProAla: 4.864 ± 0.038	0.577ProCys: 0.577 ± 0.008	3.262ProAsp: 3.262 ± 0.021	3.961ProGlu: 3.961 ± 0.025	2.094ProPhe: 2.094 ± 0.016	4.017ProGly: 4.017 ± 0.042	1.282ProHis: 1.282 ± 0.016	2.56ProIle: 2.56 ± 0.018	2.797ProLys: 2.797 ± 0.022	4.542ProLeu: 4.542 ± 0.025	1.159ProMet: 1.159 ± 0.012	2.239ProAsn: 2.239 ± 0.017	4.736ProPro: 4.736 ± 0.056	2.555ProGln: 2.555 ± 0.024	3.322ProArg: 3.322 ± 0.018	5.676ProSer: 5.676 ± 0.039	3.816ProThr: 3.816 ± 0.027	3.582ProVal: 3.582 ± 0.024	0.793ProTrp: 0.793 ± 0.01	1.533ProTyr: 1.533 ± 0.015	0.0ProXaa: 0.0 ± 0.0
Gln	3.525GlnAla: 3.525 ± 0.025	0.469GlnCys: 0.469 ± 0.007	2.279GlnAsp: 2.279 ± 0.018	2.484GlnGlu: 2.484 ± 0.018	1.314GlnPhe: 1.314 ± 0.013	2.53GlnGly: 2.53 ± 0.019	1.1GlnHis: 1.1 ± 0.012	1.883GlnIle: 1.883 ± 0.015	1.964GlnLys: 1.964 ± 0.017	3.439GlnLeu: 3.439 ± 0.026	0.937GlnMet: 0.937 ± 0.014	1.631GlnAsn: 1.631 ± 0.012	2.643GlnPro: 2.643 ± 0.025	2.498GlnGln: 2.498 ± 0.034	2.552GlnArg: 2.552 ± 0.017	3.086GlnSer: 3.086 ± 0.021	2.34GlnThr: 2.34 ± 0.017	2.282GlnVal: 2.282 ± 0.017	0.604GlnTrp: 0.604 ± 0.008	1.183GlnTyr: 1.183 ± 0.012	0.0GlnXaa: 0.0 ± 0.0
Arg	4.296ArgAla: 4.296 ± 0.022	0.761ArgCys: 0.761 ± 0.01	3.365ArgAsp: 3.365 ± 0.022	3.603ArgGlu: 3.603 ± 0.025	2.169ArgPhe: 2.169 ± 0.014	3.535ArgGly: 3.535 ± 0.023	1.588ArgHis: 1.588 ± 0.016	2.91ArgIle: 2.91 ± 0.02	3.303ArgLys: 3.303 ± 0.022	5.358ArgLeu: 5.358 ± 0.031	1.303ArgMet: 1.303 ± 0.014	2.26ArgAsn: 2.26 ± 0.016	3.412ArgPro: 3.412 ± 0.023	2.573ArgGln: 2.573 ± 0.02	4.86ArgArg: 4.86 ± 0.032	4.636ArgSer: 4.636 ± 0.031	3.13ArgThr: 3.13 ± 0.02	3.24ArgVal: 3.24 ± 0.019	0.94ArgTrp: 0.94 ± 0.01	1.685ArgTyr: 1.685 ± 0.016	0.0ArgXaa: 0.0 ± 0.0
Ser	6.219SerAla: 6.219 ± 0.031	0.992SerCys: 0.992 ± 0.012	4.312SerAsp: 4.312 ± 0.022	4.215SerGlu: 4.215 ± 0.025	3.129SerPhe: 3.129 ± 0.021	5.421SerGly: 5.421 ± 0.037	1.978SerHis: 1.978 ± 0.017	4.223SerIle: 4.223 ± 0.024	3.838SerLys: 3.838 ± 0.027	7.18SerLeu: 7.18 ± 0.037	1.834SerMet: 1.834 ± 0.016	3.092SerAsn: 3.092 ± 0.018	5.302SerPro: 5.302 ± 0.036	3.36SerGln: 3.36 ± 0.022	4.947SerArg: 4.947 ± 0.029	8.25SerSer: 8.25 ± 0.054	5.37SerThr: 5.37 ± 0.032	4.526SerVal: 4.526 ± 0.025	1.209SerTrp: 1.209 ± 0.011	2.135SerTyr: 2.135 ± 0.019	0.0SerXaa: 0.0 ± 0.0
Thr	5.076ThrAla: 5.076 ± 0.029	0.833ThrCys: 0.833 ± 0.011	2.919ThrAsp: 2.919 ± 0.018	3.313ThrGlu: 3.313 ± 0.027	2.28ThrPhe: 2.28 ± 0.015	4.098ThrGly: 4.098 ± 0.027	1.282ThrHis: 1.282 ± 0.012	3.291ThrIle: 3.291 ± 0.04	2.876ThrLys: 2.876 ± 0.02	5.177ThrLeu: 5.177 ± 0.028	1.259ThrMet: 1.259 ± 0.011	2.216ThrAsn: 2.216 ± 0.018	4.223ThrPro: 4.223 ± 0.029	2.193ThrGln: 2.193 ± 0.019	3.139ThrArg: 3.139 ± 0.021	5.243ThrSer: 5.243 ± 0.032	4.335ThrThr: 4.335 ± 0.051	3.741ThrVal: 3.741 ± 0.042	0.898ThrTrp: 0.898 ± 0.01	1.654ThrTyr: 1.654 ± 0.017	0.0ThrXaa: 0.0 ± 0.0
Val	5.047ValAla: 5.047 ± 0.026	0.875ValCys: 0.875 ± 0.011	3.64ValAsp: 3.64 ± 0.023	3.804ValGlu: 3.804 ± 0.024	2.5ValPhe: 2.5 ± 0.018	3.826ValGly: 3.826 ± 0.021	1.354ValHis: 1.354 ± 0.012	3.123ValIle: 3.123 ± 0.02	3.031ValLys: 3.031 ± 0.02	5.457ValLeu: 5.457 ± 0.029	1.355ValMet: 1.355 ± 0.012	2.262ValAsn: 2.262 ± 0.017	3.524ValPro: 3.524 ± 0.027	2.39ValGln: 2.39 ± 0.017	3.224ValArg: 3.224 ± 0.019	4.645ValSer: 4.645 ± 0.025	3.654ValThr: 3.654 ± 0.04	4.173ValVal: 4.173 ± 0.026	0.871ValTrp: 0.871 ± 0.01	1.755ValTyr: 1.755 ± 0.016	0.0ValXaa: 0.0 ± 0.0
Trp	1.161TrpAla: 1.161 ± 0.012	0.215TrpCys: 0.215 ± 0.004	0.92TrpAsp: 0.92 ± 0.011	0.859TrpGlu: 0.859 ± 0.01	0.597TrpPhe: 0.597 ± 0.008	0.979TrpGly: 0.979 ± 0.012	0.381TrpHis: 0.381 ± 0.007	0.831TrpIle: 0.831 ± 0.01	0.855TrpLys: 0.855 ± 0.01	1.413TrpLeu: 1.413 ± 0.015	0.385TrpMet: 0.385 ± 0.007	0.657TrpAsn: 0.657 ± 0.008	0.657TrpPro: 0.657 ± 0.009	0.611TrpGln: 0.611 ± 0.008	0.929TrpArg: 0.929 ± 0.011	1.124TrpSer: 1.124 ± 0.012	0.965TrpThr: 0.965 ± 0.011	0.931TrpVal: 0.931 ± 0.01	0.293TrpTrp: 0.293 ± 0.006	0.453TrpTyr: 0.453 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.09TyrAla: 2.09 ± 0.018	0.445TyrCys: 0.445 ± 0.007	1.682TyrAsp: 1.682 ± 0.013	1.578TyrGlu: 1.578 ± 0.013	1.222TyrPhe: 1.222 ± 0.013	2.105TyrGly: 2.105 ± 0.019	0.784TyrHis: 0.784 ± 0.01	1.428TyrIle: 1.428 ± 0.014	1.179TyrLys: 1.179 ± 0.013	2.657TyrLeu: 2.657 ± 0.021	0.653TyrMet: 0.653 ± 0.01	1.173TyrAsn: 1.173 ± 0.013	1.471TyrPro: 1.471 ± 0.014	1.156TyrGln: 1.156 ± 0.01	1.668TyrArg: 1.668 ± 0.014	2.043TyrSer: 2.043 ± 0.017	1.63TyrThr: 1.63 ± 0.017	1.665TyrVal: 1.665 ± 0.014	0.491TyrTrp: 0.491 ± 0.007	0.95TyrTyr: 0.95 ± 0.012	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 20767 proteins (9582963 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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