Amino acid dipepetide frequency for Tortoise microvirus 19

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.501AlaAla: 9.501 ± 6.114
0.0AlaCys: 0.0 ± 0.0
4.157AlaAsp: 4.157 ± 2.233
6.532AlaGlu: 6.532 ± 2.541
1.188AlaPhe: 1.188 ± 0.955
5.938AlaGly: 5.938 ± 3.347
1.188AlaHis: 1.188 ± 1.081
6.532AlaIle: 6.532 ± 2.478
3.563AlaLys: 3.563 ± 1.282
5.938AlaLeu: 5.938 ± 2.853
1.781AlaMet: 1.781 ± 0.848
2.969AlaAsn: 2.969 ± 1.194
1.781AlaPro: 1.781 ± 0.848
3.563AlaGln: 3.563 ± 1.628
5.344AlaArg: 5.344 ± 1.144
1.781AlaSer: 1.781 ± 0.699
3.563AlaThr: 3.563 ± 0.742
5.344AlaVal: 5.344 ± 1.404
0.594AlaTrp: 0.594 ± 0.402
1.781AlaTyr: 1.781 ± 0.699
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
0.594CysGly: 0.594 ± 0.487
0.594CysHis: 0.594 ± 0.402
0.594CysIle: 0.594 ± 0.487
0.594CysLys: 0.594 ± 0.487
0.594CysLeu: 0.594 ± 0.487
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.594CysArg: 0.594 ± 0.487
0.594CysSer: 0.594 ± 0.677
0.594CysThr: 0.594 ± 0.487
0.594CysVal: 0.594 ± 0.487
0.0CysTrp: 0.0 ± 0.0
0.594CysTyr: 0.594 ± 0.402
0.0CysXaa: 0.0 ± 0.0
Asp
4.751AspAla: 4.751 ± 1.485
0.0AspCys: 0.0 ± 0.0
1.188AspAsp: 1.188 ± 0.805
5.938AspGlu: 5.938 ± 2.013
1.188AspPhe: 1.188 ± 0.805
4.157AspGly: 4.157 ± 1.687
0.594AspHis: 0.594 ± 0.487
6.532AspIle: 6.532 ± 1.779
3.563AspLys: 3.563 ± 1.181
1.188AspLeu: 1.188 ± 0.805
1.188AspMet: 1.188 ± 0.984
0.594AspAsn: 0.594 ± 0.651
0.594AspPro: 0.594 ± 0.402
1.188AspGln: 1.188 ± 0.448
1.781AspArg: 1.781 ± 0.971
1.188AspSer: 1.188 ± 0.509
4.751AspThr: 4.751 ± 1.227
2.969AspVal: 2.969 ± 1.307
1.781AspTrp: 1.781 ± 0.647
1.781AspTyr: 1.781 ± 0.647
0.0AspXaa: 0.0 ± 0.0
Glu
9.501GluAla: 9.501 ± 3.203
0.594GluCys: 0.594 ± 0.487
1.188GluAsp: 1.188 ± 0.448
12.47GluGlu: 12.47 ± 4.163
1.188GluPhe: 1.188 ± 0.683
5.344GluGly: 5.344 ± 1.255
1.188GluHis: 1.188 ± 0.448
5.344GluIle: 5.344 ± 1.108
6.532GluLys: 6.532 ± 2.945
9.501GluLeu: 9.501 ± 3.504
1.781GluMet: 1.781 ± 1.018
5.344GluAsn: 5.344 ± 1.149
1.188GluPro: 1.188 ± 0.448
5.344GluGln: 5.344 ± 1.933
8.907GluArg: 8.907 ± 3.298
3.563GluSer: 3.563 ± 2.29
6.532GluThr: 6.532 ± 2.047
5.344GluVal: 5.344 ± 1.144
1.781GluTrp: 1.781 ± 1.099
3.563GluTyr: 3.563 ± 0.71
0.0GluXaa: 0.0 ± 0.0
Phe
1.188PheAla: 1.188 ± 0.805
0.0PheCys: 0.0 ± 0.0
1.188PheAsp: 1.188 ± 0.805
1.188PheGlu: 1.188 ± 0.448
0.0PhePhe: 0.0 ± 0.0
2.969PheGly: 2.969 ± 1.539
0.594PheHis: 0.594 ± 0.402
1.188PheIle: 1.188 ± 0.448
0.594PheLys: 0.594 ± 0.85
1.781PheLeu: 1.781 ± 0.943
0.0PheMet: 0.0 ± 0.0
2.375PheAsn: 2.375 ± 1.049
1.188PhePro: 1.188 ± 0.805
2.375PheGln: 2.375 ± 0.949
1.188PheArg: 1.188 ± 0.805
1.781PheSer: 1.781 ± 1.103
3.563PheThr: 3.563 ± 1.036
2.375PheVal: 2.375 ± 0.986
0.594PheTrp: 0.594 ± 0.402
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
5.938GlyAla: 5.938 ± 4.909
0.594GlyCys: 0.594 ± 0.487
3.563GlyAsp: 3.563 ± 1.685
5.938GlyGlu: 5.938 ± 2.158
2.969GlyPhe: 2.969 ± 1.427
8.907GlyGly: 8.907 ± 2.726
1.188GlyHis: 1.188 ± 0.974
3.563GlyIle: 3.563 ± 1.076
7.72GlyLys: 7.72 ± 3.343
7.72GlyLeu: 7.72 ± 2.545
2.375GlyMet: 2.375 ± 0.46
4.751GlyAsn: 4.751 ± 2.098
1.188GlyPro: 1.188 ± 0.805
4.751GlyGln: 4.751 ± 1.91
5.344GlyArg: 5.344 ± 2.135
4.157GlySer: 4.157 ± 1.319
10.689GlyThr: 10.689 ± 3.504
4.157GlyVal: 4.157 ± 1.897
0.0GlyTrp: 0.0 ± 0.0
2.969GlyTyr: 2.969 ± 1.25
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
1.188HisAsp: 1.188 ± 0.448
0.594HisGlu: 0.594 ± 0.487
0.594HisPhe: 0.594 ± 0.651
2.375HisGly: 2.375 ± 1.049
0.0HisHis: 0.0 ± 0.0
1.188HisIle: 1.188 ± 1.002
1.188HisLys: 1.188 ± 0.448
0.0HisLeu: 0.0 ± 0.0
0.0HisMet: 0.0 ± 0.0
1.188HisAsn: 1.188 ± 0.448
0.594HisPro: 0.594 ± 0.402
1.781HisGln: 1.781 ± 0.469
1.188HisArg: 1.188 ± 0.974
1.188HisSer: 1.188 ± 0.805
0.594HisThr: 0.594 ± 0.402
0.594HisVal: 0.594 ± 0.402
0.594HisTrp: 0.594 ± 0.487
0.594HisTyr: 0.594 ± 0.402
0.0HisXaa: 0.0 ± 0.0
Ile
5.344IleAla: 5.344 ± 1.483
0.0IleCys: 0.0 ± 0.0
4.157IleAsp: 4.157 ± 2.817
10.095IleGlu: 10.095 ± 2.387
1.781IlePhe: 1.781 ± 0.699
7.72IleGly: 7.72 ± 2.1
2.375IleHis: 2.375 ± 0.809
2.375IleIle: 2.375 ± 0.425
3.563IleLys: 3.563 ± 1.755
1.781IleLeu: 1.781 ± 0.943
0.594IleMet: 0.594 ± 0.406
2.969IleAsn: 2.969 ± 0.646
1.781IlePro: 1.781 ± 0.845
2.969IleGln: 2.969 ± 0.682
4.751IleArg: 4.751 ± 1.552
3.563IleSer: 3.563 ± 0.742
4.157IleThr: 4.157 ± 1.116
2.969IleVal: 2.969 ± 2.003
0.594IleTrp: 0.594 ± 0.487
2.375IleTyr: 2.375 ± 1.049
0.0IleXaa: 0.0 ± 0.0
Lys
5.938LysAla: 5.938 ± 3.303
0.0LysCys: 0.0 ± 0.0
4.157LysAsp: 4.157 ± 1.547
6.532LysGlu: 6.532 ± 3.339
2.375LysPhe: 2.375 ± 0.897
3.563LysGly: 3.563 ± 0.823
1.781LysHis: 1.781 ± 1.461
7.126LysIle: 7.126 ± 3.02
5.938LysLys: 5.938 ± 3.001
4.751LysLeu: 4.751 ± 1.302
2.969LysMet: 2.969 ± 1.816
5.344LysAsn: 5.344 ± 1.706
2.969LysPro: 2.969 ± 1.424
3.563LysGln: 3.563 ± 0.684
1.781LysArg: 1.781 ± 1.443
2.375LysSer: 2.375 ± 2.146
4.751LysThr: 4.751 ± 1.052
3.563LysVal: 3.563 ± 1.715
1.781LysTrp: 1.781 ± 1.098
4.157LysTyr: 4.157 ± 2.977
0.0LysXaa: 0.0 ± 0.0
Leu
4.751LeuAla: 4.751 ± 2.083
0.0LeuCys: 0.0 ± 0.0
2.375LeuAsp: 2.375 ± 1.241
7.72LeuGlu: 7.72 ± 1.813
0.0LeuPhe: 0.0 ± 0.0
8.907LeuGly: 8.907 ± 2.645
1.188LeuHis: 1.188 ± 0.805
2.969LeuIle: 2.969 ± 1.038
2.969LeuLys: 2.969 ± 1.918
3.563LeuLeu: 3.563 ± 1.084
1.781LeuMet: 1.781 ± 0.894
5.938LeuAsn: 5.938 ± 1.239
1.188LeuPro: 1.188 ± 0.448
2.969LeuGln: 2.969 ± 1.187
0.0LeuArg: 0.0 ± 0.0
3.563LeuSer: 3.563 ± 1.989
5.344LeuThr: 5.344 ± 0.849
1.781LeuVal: 1.781 ± 1.098
1.188LeuTrp: 1.188 ± 0.82
4.157LeuTyr: 4.157 ± 0.93
0.0LeuXaa: 0.0 ± 0.0
Met
0.594MetAla: 0.594 ± 0.651
0.594MetCys: 0.594 ± 0.487
1.188MetAsp: 1.188 ± 0.805
1.781MetGlu: 1.781 ± 1.938
0.594MetPhe: 0.594 ± 0.487
3.563MetGly: 3.563 ± 1.076
0.0MetHis: 0.0 ± 0.0
2.375MetIle: 2.375 ± 1.61
2.969MetLys: 2.969 ± 1.865
1.188MetLeu: 1.188 ± 0.924
0.0MetMet: 0.0 ± 0.0
0.594MetAsn: 0.594 ± 0.941
1.781MetPro: 1.781 ± 1.207
1.188MetGln: 1.188 ± 0.955
2.969MetArg: 2.969 ± 1.309
2.375MetSer: 2.375 ± 1.049
2.375MetThr: 2.375 ± 0.425
0.594MetVal: 0.594 ± 0.487
0.0MetTrp: 0.0 ± 0.0
0.594MetTyr: 0.594 ± 0.402
0.0MetXaa: 0.0 ± 0.0
Asn
4.157AsnAla: 4.157 ± 1.319
0.594AsnCys: 0.594 ± 0.487
0.594AsnAsp: 0.594 ± 0.402
7.126AsnGlu: 7.126 ± 2.813
2.969AsnPhe: 2.969 ± 0.581
3.563AsnGly: 3.563 ± 1.345
0.594AsnHis: 0.594 ± 0.402
4.751AsnIle: 4.751 ± 0.856
5.938AsnLys: 5.938 ± 0.944
2.969AsnLeu: 2.969 ± 2.012
0.0AsnMet: 0.0 ± 0.0
3.563AsnAsn: 3.563 ± 1.815
1.781AsnPro: 1.781 ± 0.845
1.188AsnGln: 1.188 ± 0.509
1.781AsnArg: 1.781 ± 0.699
2.969AsnSer: 2.969 ± 1.656
4.751AsnThr: 4.751 ± 1.081
1.188AsnVal: 1.188 ± 0.805
1.781AsnTrp: 1.781 ± 0.647
2.375AsnTyr: 2.375 ± 0.986
0.0AsnXaa: 0.0 ± 0.0
Pro
1.781ProAla: 1.781 ± 0.777
0.594ProCys: 0.594 ± 0.402
1.781ProAsp: 1.781 ± 0.647
0.594ProGlu: 0.594 ± 0.402
1.188ProPhe: 1.188 ± 0.805
2.969ProGly: 2.969 ± 0.97
0.0ProHis: 0.0 ± 0.0
1.781ProIle: 1.781 ± 0.848
2.375ProLys: 2.375 ± 1.049
2.969ProLeu: 2.969 ± 1.56
0.0ProMet: 0.0 ± 0.0
1.781ProAsn: 1.781 ± 1.207
0.594ProPro: 0.594 ± 0.487
1.781ProGln: 1.781 ± 0.699
0.594ProArg: 0.594 ± 0.402
2.969ProSer: 2.969 ± 1.323
0.594ProThr: 0.594 ± 0.402
1.781ProVal: 1.781 ± 0.845
0.0ProTrp: 0.0 ± 0.0
0.594ProTyr: 0.594 ± 0.402
0.0ProXaa: 0.0 ± 0.0
Gln
2.969GlnAla: 2.969 ± 3.256
0.594GlnCys: 0.594 ± 0.402
1.781GlnAsp: 1.781 ± 1.023
2.969GlnGlu: 2.969 ± 1.218
0.0GlnPhe: 0.0 ± 0.0
4.751GlnGly: 4.751 ± 1.395
0.0GlnHis: 0.0 ± 0.0
1.188GlnIle: 1.188 ± 0.805
1.781GlnLys: 1.781 ± 0.647
1.781GlnLeu: 1.781 ± 0.699
2.375GlnMet: 2.375 ± 1.175
2.375GlnAsn: 2.375 ± 1.506
3.563GlnPro: 3.563 ± 2.414
2.375GlnGln: 2.375 ± 0.809
3.563GlnArg: 3.563 ± 1.708
2.969GlnSer: 2.969 ± 1.582
2.375GlnThr: 2.375 ± 1.452
2.969GlnVal: 2.969 ± 1.307
0.594GlnTrp: 0.594 ± 0.402
1.781GlnTyr: 1.781 ± 0.469
0.0GlnXaa: 0.0 ± 0.0
Arg
1.781ArgAla: 1.781 ± 0.647
0.594ArgCys: 0.594 ± 0.487
1.781ArgAsp: 1.781 ± 1.393
4.751ArgGlu: 4.751 ± 1.827
1.188ArgPhe: 1.188 ± 0.448
5.938ArgGly: 5.938 ± 0.926
0.0ArgHis: 0.0 ± 0.0
4.751ArgIle: 4.751 ± 1.307
7.126ArgLys: 7.126 ± 2.613
2.375ArgLeu: 2.375 ± 1.018
3.563ArgMet: 3.563 ± 2.834
4.751ArgAsn: 4.751 ± 2.089
0.0ArgPro: 0.0 ± 0.0
0.594ArgGln: 0.594 ± 0.402
4.157ArgArg: 4.157 ± 1.029
3.563ArgSer: 3.563 ± 0.626
2.969ArgThr: 2.969 ± 0.943
5.938ArgVal: 5.938 ± 1.865
0.594ArgTrp: 0.594 ± 0.487
0.594ArgTyr: 0.594 ± 0.402
0.0ArgXaa: 0.0 ± 0.0
Ser
2.969SerAla: 2.969 ± 1.582
0.594SerCys: 0.594 ± 0.487
5.344SerAsp: 5.344 ± 1.903
5.344SerGlu: 5.344 ± 1.648
1.781SerPhe: 1.781 ± 0.971
2.969SerGly: 2.969 ± 1.218
0.0SerHis: 0.0 ± 0.0
3.563SerIle: 3.563 ± 1.043
5.344SerLys: 5.344 ± 2.098
4.157SerLeu: 4.157 ± 3.095
1.781SerMet: 1.781 ± 0.845
0.0SerAsn: 0.0 ± 0.0
2.375SerPro: 2.375 ± 0.425
2.375SerGln: 2.375 ± 1.506
1.188SerArg: 1.188 ± 1.063
3.563SerSer: 3.563 ± 2.414
4.751SerThr: 4.751 ± 1.678
1.188SerVal: 1.188 ± 0.448
0.594SerTrp: 0.594 ± 0.402
2.375SerTyr: 2.375 ± 1.305
0.0SerXaa: 0.0 ± 0.0
Thr
4.157ThrAla: 4.157 ± 1.786
0.0ThrCys: 0.0 ± 0.0
4.157ThrAsp: 4.157 ± 1.786
8.907ThrGlu: 8.907 ± 1.381
2.375ThrPhe: 2.375 ± 1.048
6.532ThrGly: 6.532 ± 0.919
2.375ThrHis: 2.375 ± 1.61
3.563ThrIle: 3.563 ± 1.933
6.532ThrLys: 6.532 ± 1.817
4.157ThrLeu: 4.157 ± 1.736
2.969ThrMet: 2.969 ± 1.427
3.563ThrAsn: 3.563 ± 0.626
1.781ThrPro: 1.781 ± 0.77
2.375ThrGln: 2.375 ± 2.231
3.563ThrArg: 3.563 ± 1.341
4.751ThrSer: 4.751 ± 1.967
6.532ThrThr: 6.532 ± 3.078
3.563ThrVal: 3.563 ± 1.58
1.781ThrTrp: 1.781 ± 0.647
4.157ThrTyr: 4.157 ± 1.721
0.0ThrXaa: 0.0 ± 0.0
Val
5.344ValAla: 5.344 ± 1.588
1.188ValCys: 1.188 ± 0.82
3.563ValAsp: 3.563 ± 2.414
5.344ValGlu: 5.344 ± 2.109
3.563ValPhe: 3.563 ± 2.414
2.969ValGly: 2.969 ± 1.326
1.188ValHis: 1.188 ± 0.448
1.188ValIle: 1.188 ± 0.805
2.969ValLys: 2.969 ± 1.674
1.781ValLeu: 1.781 ± 0.699
1.781ValMet: 1.781 ± 0.845
2.969ValAsn: 2.969 ± 1.25
1.781ValPro: 1.781 ± 0.971
1.188ValGln: 1.188 ± 0.805
3.563ValArg: 3.563 ± 0.742
2.969ValSer: 2.969 ± 0.567
4.157ValThr: 4.157 ± 0.887
2.969ValVal: 2.969 ± 1.604
0.0ValTrp: 0.0 ± 0.0
1.781ValTyr: 1.781 ± 1.207
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
2.969TrpAsp: 2.969 ± 0.963
0.594TrpGlu: 0.594 ± 0.651
0.594TrpPhe: 0.594 ± 0.487
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
1.781TrpIle: 1.781 ± 0.469
1.188TrpLys: 1.188 ± 0.763
1.188TrpLeu: 1.188 ± 0.805
1.188TrpMet: 1.188 ± 0.805
1.188TrpAsn: 1.188 ± 0.984
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
1.781TrpArg: 1.781 ± 1.103
0.594TrpSer: 0.594 ± 0.651
1.188TrpThr: 1.188 ± 0.805
1.188TrpVal: 1.188 ± 0.509
0.594TrpTrp: 0.594 ± 0.402
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.375TyrAla: 2.375 ± 0.897
0.0TyrCys: 0.0 ± 0.0
0.594TyrAsp: 0.594 ± 0.402
1.781TyrGlu: 1.781 ± 0.699
0.594TyrPhe: 0.594 ± 0.402
4.751TyrGly: 4.751 ± 0.849
0.594TyrHis: 0.594 ± 0.402
3.563TyrIle: 3.563 ± 1.294
3.563TyrLys: 3.563 ± 1.081
2.969TyrLeu: 2.969 ± 0.646
0.594TyrMet: 0.594 ± 0.487
2.375TyrAsn: 2.375 ± 0.425
0.594TyrPro: 0.594 ± 0.402
1.188TyrGln: 1.188 ± 0.805
2.969TyrArg: 2.969 ± 1.262
1.781TyrSer: 1.781 ± 0.695
3.563TyrThr: 3.563 ± 0.673
1.188TyrVal: 1.188 ± 0.974
1.188TyrTrp: 1.188 ± 0.509
1.188TyrTyr: 1.188 ± 0.448
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1685 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski