Amino acid dipepetide frequency for Monilinia laxa

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.16AlaAla: 7.16 ± 0.051	0.892AlaCys: 0.892 ± 0.014	3.518AlaAsp: 3.518 ± 0.029	4.658AlaGlu: 4.658 ± 0.04	2.808AlaPhe: 2.808 ± 0.028	5.105AlaGly: 5.105 ± 0.038	1.546AlaHis: 1.546 ± 0.016	4.294AlaIle: 4.294 ± 0.03	4.093AlaLys: 4.093 ± 0.035	6.672AlaLeu: 6.672 ± 0.042	1.75AlaMet: 1.75 ± 0.019	2.989AlaAsn: 2.989 ± 0.023	4.317AlaPro: 4.317 ± 0.042	3.049AlaGln: 3.049 ± 0.026	4.081AlaArg: 4.081 ± 0.031	6.82AlaSer: 6.82 ± 0.053	4.882AlaThr: 4.882 ± 0.036	4.388AlaVal: 4.388 ± 0.03	0.969AlaTrp: 0.969 ± 0.016	1.992AlaTyr: 1.992 ± 0.02	0.0AlaXaa: 0.0 ± 0.0
Cys	0.799CysAla: 0.799 ± 0.012	0.241CysCys: 0.241 ± 0.007	0.596CysAsp: 0.596 ± 0.01	0.591CysGlu: 0.591 ± 0.012	0.516CysPhe: 0.516 ± 0.01	0.913CysGly: 0.913 ± 0.016	0.303CysHis: 0.303 ± 0.008	0.737CysIle: 0.737 ± 0.013	0.56CysLys: 0.56 ± 0.009	1.154CysLeu: 1.154 ± 0.016	0.283CysMet: 0.283 ± 0.007	0.454CysAsn: 0.454 ± 0.009	0.611CysPro: 0.611 ± 0.012	0.4CysGln: 0.4 ± 0.008	0.627CysArg: 0.627 ± 0.011	0.907CysSer: 0.907 ± 0.015	0.684CysThr: 0.684 ± 0.014	0.712CysVal: 0.712 ± 0.012	0.182CysTrp: 0.182 ± 0.006	0.365CysTyr: 0.365 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	4.006AspAla: 4.006 ± 0.031	0.6AspCys: 0.6 ± 0.011	4.215AspAsp: 4.215 ± 0.046	4.617AspGlu: 4.617 ± 0.04	2.21AspPhe: 2.21 ± 0.022	3.909AspGly: 3.909 ± 0.032	1.16AspHis: 1.16 ± 0.015	3.312AspIle: 3.312 ± 0.029	2.372AspLys: 2.372 ± 0.023	4.861AspLeu: 4.861 ± 0.029	1.212AspMet: 1.212 ± 0.017	2.068AspAsn: 2.068 ± 0.023	2.936AspPro: 2.936 ± 0.025	1.754AspGln: 1.754 ± 0.021	2.737AspArg: 2.737 ± 0.027	4.221AspSer: 4.221 ± 0.033	2.907AspThr: 2.907 ± 0.023	3.326AspVal: 3.326 ± 0.03	0.813AspTrp: 0.813 ± 0.012	1.556AspTyr: 1.556 ± 0.015	0.0AspXaa: 0.0 ± 0.0
Glu	4.886GluAla: 4.886 ± 0.037	0.586GluCys: 0.586 ± 0.012	4.413GluAsp: 4.413 ± 0.041	6.312GluGlu: 6.312 ± 0.069	2.089GluPhe: 2.089 ± 0.019	4.02GluGly: 4.02 ± 0.031	1.293GluHis: 1.293 ± 0.015	3.64GluIle: 3.64 ± 0.03	4.462GluLys: 4.462 ± 0.045	5.044GluLeu: 5.044 ± 0.039	1.6GluMet: 1.6 ± 0.016	2.835GluAsn: 2.835 ± 0.025	2.635GluPro: 2.635 ± 0.042	2.333GluGln: 2.333 ± 0.027	4.149GluArg: 4.149 ± 0.045	4.605GluSer: 4.605 ± 0.04	3.418GluThr: 3.418 ± 0.029	3.713GluVal: 3.713 ± 0.031	0.878GluTrp: 0.878 ± 0.014	1.751GluTyr: 1.751 ± 0.019	0.0GluXaa: 0.0 ± 0.0
Phe	2.785PheAla: 2.785 ± 0.027	0.557PheCys: 0.557 ± 0.01	2.234PheAsp: 2.234 ± 0.021	2.28PheGlu: 2.28 ± 0.023	1.634PhePhe: 1.634 ± 0.025	2.85PheGly: 2.85 ± 0.028	0.944PheHis: 0.944 ± 0.014	1.987PheIle: 1.987 ± 0.022	1.705PheLys: 1.705 ± 0.018	3.426PheLeu: 3.426 ± 0.029	0.829PheMet: 0.829 ± 0.013	1.612PheAsn: 1.612 ± 0.018	1.995PhePro: 1.995 ± 0.02	1.426PheGln: 1.426 ± 0.017	1.8PheArg: 1.8 ± 0.023	3.237PheSer: 3.237 ± 0.026	2.269PheThr: 2.269 ± 0.023	2.206PheVal: 2.206 ± 0.022	0.617PheTrp: 0.617 ± 0.011	1.144PheTyr: 1.144 ± 0.014	0.0PheXaa: 0.0 ± 0.0
Gly	4.713GlyAla: 4.713 ± 0.036	0.838GlyCys: 0.838 ± 0.013	3.539GlyAsp: 3.539 ± 0.027	3.917GlyGlu: 3.917 ± 0.026	2.771GlyPhe: 2.771 ± 0.023	6.024GlyGly: 6.024 ± 0.057	1.544GlyHis: 1.544 ± 0.018	3.801GlyIle: 3.801 ± 0.024	3.873GlyLys: 3.873 ± 0.032	5.688GlyLeu: 5.688 ± 0.033	1.711GlyMet: 1.711 ± 0.02	2.95GlyAsn: 2.95 ± 0.031	2.982GlyPro: 2.982 ± 0.024	2.283GlyGln: 2.283 ± 0.023	3.947GlyArg: 3.947 ± 0.034	5.826GlySer: 5.826 ± 0.043	3.961GlyThr: 3.961 ± 0.031	4.181GlyVal: 4.181 ± 0.036	1.131GlyTrp: 1.131 ± 0.016	2.166GlyTyr: 2.166 ± 0.023	0.0GlyXaa: 0.0 ± 0.0
His	1.553HisAla: 1.553 ± 0.019	0.31HisCys: 0.31 ± 0.009	1.243HisAsp: 1.243 ± 0.016	1.309HisGlu: 1.309 ± 0.018	0.935HisPhe: 0.935 ± 0.013	1.574HisGly: 1.574 ± 0.018	0.9HisHis: 0.9 ± 0.016	1.333HisIle: 1.333 ± 0.018	1.027HisLys: 1.027 ± 0.014	2.168HisLeu: 2.168 ± 0.021	0.472HisMet: 0.472 ± 0.01	1.001HisAsn: 1.001 ± 0.015	1.632HisPro: 1.632 ± 0.019	1.039HisGln: 1.039 ± 0.016	1.378HisArg: 1.378 ± 0.017	1.985HisSer: 1.985 ± 0.022	1.395HisThr: 1.395 ± 0.018	1.249HisVal: 1.249 ± 0.015	0.298HisTrp: 0.298 ± 0.007	0.695HisTyr: 0.695 ± 0.011	0.0HisXaa: 0.0 ± 0.0
Ile	4.176IleAla: 4.176 ± 0.028	0.809IleCys: 0.809 ± 0.013	3.131IleAsp: 3.131 ± 0.026	3.372IleGlu: 3.372 ± 0.03	2.227IlePhe: 2.227 ± 0.021	3.455IleGly: 3.455 ± 0.028	1.406IleHis: 1.406 ± 0.017	3.156IleIle: 3.156 ± 0.031	2.757IleLys: 2.757 ± 0.026	4.999IleLeu: 4.999 ± 0.037	1.17IleMet: 1.17 ± 0.014	2.323IleAsn: 2.323 ± 0.023	3.632IlePro: 3.632 ± 0.027	2.149IleGln: 2.149 ± 0.022	2.825IleArg: 2.825 ± 0.025	4.868IleSer: 4.868 ± 0.035	3.326IleThr: 3.326 ± 0.027	3.227IleVal: 3.227 ± 0.028	0.757IleTrp: 0.757 ± 0.015	1.667IleTyr: 1.667 ± 0.018	0.0IleXaa: 0.0 ± 0.0
Lys	4.289LysAla: 4.289 ± 0.035	0.542LysCys: 0.542 ± 0.011	3.102LysAsp: 3.102 ± 0.027	4.09LysGlu: 4.09 ± 0.043	1.712LysPhe: 1.712 ± 0.018	3.359LysGly: 3.359 ± 0.029	1.182LysHis: 1.182 ± 0.015	2.868LysIle: 2.868 ± 0.026	4.213LysLys: 4.213 ± 0.049	4.411LysLeu: 4.411 ± 0.033	1.19LysMet: 1.19 ± 0.017	2.268LysAsn: 2.268 ± 0.02	2.861LysPro: 2.861 ± 0.024	1.903LysGln: 1.903 ± 0.021	3.713LysArg: 3.713 ± 0.035	4.354LysSer: 4.354 ± 0.035	3.154LysThr: 3.154 ± 0.023	3.117LysVal: 3.117 ± 0.028	0.725LysTrp: 0.725 ± 0.013	1.549LysTyr: 1.549 ± 0.017	0.0LysXaa: 0.0 ± 0.0
Leu	6.749LeuAla: 6.749 ± 0.04	1.114LeuCys: 1.114 ± 0.015	4.725LeuAsp: 4.725 ± 0.032	5.507LeuGlu: 5.507 ± 0.045	3.231LeuPhe: 3.231 ± 0.033	5.633LeuGly: 5.633 ± 0.032	2.11LeuHis: 2.11 ± 0.022	4.252LeuIle: 4.252 ± 0.032	4.652LeuLys: 4.652 ± 0.031	7.859LeuLeu: 7.859 ± 0.061	1.76LeuMet: 1.76 ± 0.02	3.497LeuAsn: 3.497 ± 0.026	5.375LeuPro: 5.375 ± 0.035	3.647LeuGln: 3.647 ± 0.033	5.088LeuArg: 5.088 ± 0.037	7.391LeuSer: 7.391 ± 0.049	4.74LeuThr: 4.74 ± 0.03	4.796LeuVal: 4.796 ± 0.036	1.075LeuTrp: 1.075 ± 0.015	2.339LeuTyr: 2.339 ± 0.023	0.0LeuXaa: 0.0 ± 0.0
Met	1.998MetAla: 1.998 ± 0.02	0.227MetCys: 0.227 ± 0.007	1.294MetAsp: 1.294 ± 0.018	1.404MetGlu: 1.404 ± 0.019	0.764MetPhe: 0.764 ± 0.013	1.6MetGly: 1.6 ± 0.019	0.493MetHis: 0.493 ± 0.009	1.162MetIle: 1.162 ± 0.014	1.206MetLys: 1.206 ± 0.018	1.699MetLeu: 1.699 ± 0.015	0.621MetMet: 0.621 ± 0.012	0.979MetAsn: 0.979 ± 0.013	1.172MetPro: 1.172 ± 0.015	0.866MetGln: 0.866 ± 0.013	1.241MetArg: 1.241 ± 0.014	1.925MetSer: 1.925 ± 0.021	1.305MetThr: 1.305 ± 0.016	1.276MetVal: 1.276 ± 0.015	0.247MetTrp: 0.247 ± 0.007	0.536MetTyr: 0.536 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	3.124AsnAla: 3.124 ± 0.026	0.491AsnCys: 0.491 ± 0.01	2.203AsnAsp: 2.203 ± 0.022	2.431AsnGlu: 2.431 ± 0.02	1.673AsnPhe: 1.673 ± 0.017	3.425AsnGly: 3.425 ± 0.03	1.059AsnHis: 1.059 ± 0.012	2.567AsnIle: 2.567 ± 0.022	1.952AsnLys: 1.952 ± 0.02	3.729AsnLeu: 3.729 ± 0.029	0.952AsnMet: 0.952 ± 0.014	2.049AsnAsn: 2.049 ± 0.032	2.697AsnPro: 2.697 ± 0.025	1.574AsnGln: 1.574 ± 0.02	2.109AsnArg: 2.109 ± 0.024	3.691AsnSer: 3.691 ± 0.031	2.77AsnThr: 2.77 ± 0.03	2.375AsnVal: 2.375 ± 0.023	0.574AsnTrp: 0.574 ± 0.01	1.241AsnTyr: 1.241 ± 0.017	0.0AsnXaa: 0.0 ± 0.0
Pro	4.389ProAla: 4.389 ± 0.042	0.474ProCys: 0.474 ± 0.01	2.729ProAsp: 2.729 ± 0.023	3.596ProGlu: 3.596 ± 0.033	2.023ProPhe: 2.023 ± 0.02	3.491ProGly: 3.491 ± 0.029	1.34ProHis: 1.34 ± 0.019	3.163ProIle: 3.163 ± 0.032	2.994ProLys: 2.994 ± 0.03	4.589ProLeu: 4.589 ± 0.032	1.047ProMet: 1.047 ± 0.018	2.539ProAsn: 2.539 ± 0.027	5.007ProPro: 5.007 ± 0.066	2.545ProGln: 2.545 ± 0.036	3.189ProArg: 3.189 ± 0.032	6.308ProSer: 6.308 ± 0.05	4.247ProThr: 4.247 ± 0.032	3.186ProVal: 3.186 ± 0.032	0.627ProTrp: 0.627 ± 0.011	1.544ProTyr: 1.544 ± 0.02	0.0ProXaa: 0.0 ± 0.0
Gln	3.061GlnAla: 3.061 ± 0.024	0.407GlnCys: 0.407 ± 0.009	1.922GlnAsp: 1.922 ± 0.021	2.412GlnGlu: 2.412 ± 0.026	1.286GlnPhe: 1.286 ± 0.017	2.253GlnGly: 2.253 ± 0.022	1.043GlnHis: 1.043 ± 0.015	2.075GlnIle: 2.075 ± 0.02	2.282GlnLys: 2.282 ± 0.021	3.169GlnLeu: 3.169 ± 0.029	0.882GlnMet: 0.882 ± 0.015	1.866GlnAsn: 1.866 ± 0.023	2.302GlnPro: 2.302 ± 0.03	2.441GlnGln: 2.441 ± 0.055	2.414GlnArg: 2.414 ± 0.024	3.382GlnSer: 3.382 ± 0.032	2.297GlnThr: 2.297 ± 0.023	2.005GlnVal: 2.005 ± 0.019	0.504GlnTrp: 0.504 ± 0.009	1.251GlnTyr: 1.251 ± 0.017	0.0GlnXaa: 0.0 ± 0.0
Arg	3.995ArgAla: 3.995 ± 0.03	0.631ArgCys: 0.631 ± 0.013	3.096ArgAsp: 3.096 ± 0.033	3.976ArgGlu: 3.976 ± 0.039	1.963ArgPhe: 1.963 ± 0.019	3.695ArgGly: 3.695 ± 0.032	1.368ArgHis: 1.368 ± 0.018	3.011ArgIle: 3.011 ± 0.029	3.741ArgLys: 3.741 ± 0.03	4.722ArgLeu: 4.722 ± 0.036	1.265ArgMet: 1.265 ± 0.014	2.509ArgAsn: 2.509 ± 0.024	3.059ArgPro: 3.059 ± 0.03	2.318ArgGln: 2.318 ± 0.025	4.526ArgArg: 4.526 ± 0.044	4.715ArgSer: 4.715 ± 0.04	3.064ArgThr: 3.064 ± 0.026	2.986ArgVal: 2.986 ± 0.022	0.796ArgTrp: 0.796 ± 0.014	1.591ArgTyr: 1.591 ± 0.014	0.0ArgXaa: 0.0 ± 0.0
Ser	6.294SerAla: 6.294 ± 0.049	0.885SerCys: 0.885 ± 0.013	4.233SerAsp: 4.233 ± 0.033	4.503SerGlu: 4.503 ± 0.034	3.302SerPhe: 3.302 ± 0.025	5.638SerGly: 5.638 ± 0.042	2.118SerHis: 2.118 ± 0.021	5.094SerIle: 5.094 ± 0.039	4.515SerLys: 4.515 ± 0.032	7.332SerLeu: 7.332 ± 0.041	1.816SerMet: 1.816 ± 0.02	3.947SerAsn: 3.947 ± 0.032	5.887SerPro: 5.887 ± 0.062	3.526SerGln: 3.526 ± 0.036	4.93SerArg: 4.93 ± 0.039	10.349SerSer: 10.349 ± 0.131	6.461SerThr: 6.461 ± 0.06	4.371SerVal: 4.371 ± 0.035	1.049SerTrp: 1.049 ± 0.017	2.334SerTyr: 2.334 ± 0.024	0.0SerXaa: 0.0 ± 0.0
Thr	4.62ThrAla: 4.62 ± 0.032	0.711ThrCys: 0.711 ± 0.013	2.697ThrAsp: 2.697 ± 0.023	3.183ThrGlu: 3.183 ± 0.027	2.383ThrPhe: 2.383 ± 0.025	4.067ThrGly: 4.067 ± 0.035	1.364ThrHis: 1.364 ± 0.016	3.634ThrIle: 3.634 ± 0.03	3.018ThrLys: 3.018 ± 0.025	5.206ThrLeu: 5.206 ± 0.035	1.195ThrMet: 1.195 ± 0.016	2.606ThrAsn: 2.606 ± 0.024	4.64ThrPro: 4.64 ± 0.043	2.196ThrGln: 2.196 ± 0.023	3.002ThrArg: 3.002 ± 0.025	6.303ThrSer: 6.303 ± 0.059	4.74ThrThr: 4.74 ± 0.047	3.329ThrVal: 3.329 ± 0.025	0.768ThrTrp: 0.768 ± 0.014	1.764ThrTyr: 1.764 ± 0.02	0.0ThrXaa: 0.0 ± 0.0
Val	4.433ValAla: 4.433 ± 0.033	0.709ValCys: 0.709 ± 0.011	3.413ValAsp: 3.413 ± 0.029	4.009ValGlu: 4.009 ± 0.032	2.265ValPhe: 2.265 ± 0.024	3.855ValGly: 3.855 ± 0.027	1.221ValHis: 1.221 ± 0.015	2.997ValIle: 2.997 ± 0.027	3.072ValLys: 3.072 ± 0.029	4.949ValLeu: 4.949 ± 0.035	1.27ValMet: 1.27 ± 0.015	2.244ValAsn: 2.244 ± 0.02	3.22ValPro: 3.22 ± 0.028	2.115ValGln: 2.115 ± 0.02	2.918ValArg: 2.918 ± 0.027	4.424ValSer: 4.424 ± 0.036	3.245ValThr: 3.245 ± 0.027	3.816ValVal: 3.816 ± 0.032	0.781ValTrp: 0.781 ± 0.012	1.589ValTyr: 1.589 ± 0.018	0.0ValXaa: 0.0 ± 0.0
Trp	0.962TrpAla: 0.962 ± 0.013	0.185TrpCys: 0.185 ± 0.006	0.828TrpAsp: 0.828 ± 0.016	0.857TrpGlu: 0.857 ± 0.014	0.495TrpPhe: 0.495 ± 0.01	0.942TrpGly: 0.942 ± 0.015	0.317TrpHis: 0.317 ± 0.008	0.779TrpIle: 0.779 ± 0.013	0.827TrpLys: 0.827 ± 0.013	1.181TrpLeu: 1.181 ± 0.017	0.376TrpMet: 0.376 ± 0.008	0.649TrpAsn: 0.649 ± 0.012	0.503TrpPro: 0.503 ± 0.01	0.494TrpGln: 0.494 ± 0.01	0.839TrpArg: 0.839 ± 0.011	0.987TrpSer: 0.987 ± 0.015	0.802TrpThr: 0.802 ± 0.014	0.79TrpVal: 0.79 ± 0.013	0.256TrpTrp: 0.256 ± 0.007	0.396TrpTyr: 0.396 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.991TyrAla: 1.991 ± 0.021	0.426TyrCys: 0.426 ± 0.009	1.664TyrAsp: 1.664 ± 0.017	1.638TyrGlu: 1.638 ± 0.018	1.251TyrPhe: 1.251 ± 0.014	2.037TyrGly: 2.037 ± 0.024	0.784TyrHis: 0.784 ± 0.011	1.575TyrIle: 1.575 ± 0.018	1.279TyrLys: 1.279 ± 0.015	2.682TyrLeu: 2.682 ± 0.027	0.611TyrMet: 0.611 ± 0.011	1.302TyrAsn: 1.302 ± 0.016	1.566TyrPro: 1.566 ± 0.021	1.194TyrGln: 1.194 ± 0.016	1.516TyrArg: 1.516 ± 0.019	2.284TyrSer: 2.284 ± 0.024	1.755TyrThr: 1.755 ± 0.02	1.496TyrVal: 1.496 ± 0.015	0.417TyrTrp: 0.417 ± 0.009	0.973TyrTyr: 0.973 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 12416 proteins (5571812 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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