Amino acid dipepetide frequency for Papio anubis (Olive baboon)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.741AlaAla: 6.741 ± 0.037	1.372AlaCys: 1.372 ± 0.01	2.913AlaAsp: 2.913 ± 0.012	4.769AlaGlu: 4.769 ± 0.021	2.614AlaPhe: 2.614 ± 0.012	4.74AlaGly: 4.74 ± 0.022	1.545AlaHis: 1.545 ± 0.009	2.764AlaIle: 2.764 ± 0.011	3.461AlaLys: 3.461 ± 0.019	7.032AlaLeu: 7.032 ± 0.028	1.484AlaMet: 1.484 ± 0.009	2.026AlaAsn: 2.026 ± 0.01	4.145AlaPro: 4.145 ± 0.021	3.228AlaGln: 3.228 ± 0.016	3.652AlaArg: 3.652 ± 0.016	5.716AlaSer: 5.716 ± 0.018	3.625AlaThr: 3.625 ± 0.018	4.68AlaVal: 4.68 ± 0.016	0.811AlaTrp: 0.811 ± 0.007	1.506AlaTyr: 1.506 ± 0.009	0.0AlaXaa: 0.0 ± 0.0
Cys	1.228CysAla: 1.228 ± 0.01	0.651CysCys: 0.651 ± 0.009	1.01CysAsp: 1.01 ± 0.009	1.32CysGlu: 1.32 ± 0.012	0.845CysPhe: 0.845 ± 0.007	1.745CysGly: 1.745 ± 0.015	0.678CysHis: 0.678 ± 0.006	0.966CysIle: 0.966 ± 0.008	1.176CysLys: 1.176 ± 0.009	2.196CysLeu: 2.196 ± 0.013	0.415CysMet: 0.415 ± 0.005	0.824CysAsn: 0.824 ± 0.008	1.384CysPro: 1.384 ± 0.013	1.088CysGln: 1.088 ± 0.011	1.304CysArg: 1.304 ± 0.009	2.007CysSer: 2.007 ± 0.012	1.088CysThr: 1.088 ± 0.009	1.315CysVal: 1.315 ± 0.01	0.304CysTrp: 0.304 ± 0.003	0.572CysTyr: 0.572 ± 0.006	0.0CysXaa: 0.0 ± 0.0
Asp	2.86AspAla: 2.86 ± 0.013	1.057AspCys: 1.057 ± 0.009	2.66AspAsp: 2.66 ± 0.016	3.481AspGlu: 3.481 ± 0.016	2.116AspPhe: 2.116 ± 0.011	3.332AspGly: 3.332 ± 0.02	1.132AspHis: 1.132 ± 0.007	2.614AspIle: 2.614 ± 0.012	2.569AspLys: 2.569 ± 0.014	5.011AspLeu: 5.011 ± 0.019	1.123AspMet: 1.123 ± 0.008	1.681AspAsn: 1.681 ± 0.01	2.889AspPro: 2.889 ± 0.013	1.838AspGln: 1.838 ± 0.01	2.43AspArg: 2.43 ± 0.013	4.204AspSer: 4.204 ± 0.016	2.485AspThr: 2.485 ± 0.013	3.083AspVal: 3.083 ± 0.018	0.622AspTrp: 0.622 ± 0.005	1.495AspTyr: 1.495 ± 0.009	0.0AspXaa: 0.0 ± 0.0
Glu	5.269GluAla: 5.269 ± 0.021	1.506GluCys: 1.506 ± 0.019	4.486GluAsp: 4.486 ± 0.018	8.043GluGlu: 8.043 ± 0.045	2.043GluPhe: 2.043 ± 0.011	4.214GluGly: 4.214 ± 0.017	1.527GluHis: 1.527 ± 0.009	3.215GluIle: 3.215 ± 0.014	5.527GluLys: 5.527 ± 0.029	6.505GluLeu: 6.505 ± 0.031	1.699GluMet: 1.699 ± 0.009	3.208GluAsn: 3.208 ± 0.016	3.271GluPro: 3.271 ± 0.021	3.16GluGln: 3.16 ± 0.019	4.03GluArg: 4.03 ± 0.021	4.407GluSer: 4.407 ± 0.018	3.424GluThr: 3.424 ± 0.013	4.211GluVal: 4.211 ± 0.019	0.71GluTrp: 0.71 ± 0.006	1.628GluTyr: 1.628 ± 0.016	0.001GluXaa: 0.001 ± 0.0
Phe	1.946PheAla: 1.946 ± 0.011	0.914PheCys: 0.914 ± 0.007	1.682PheAsp: 1.682 ± 0.01	2.026PheGlu: 2.026 ± 0.011	1.571PhePhe: 1.571 ± 0.011	2.188PheGly: 2.188 ± 0.012	1.054PheHis: 1.054 ± 0.007	1.8PheIle: 1.8 ± 0.012	1.82PheLys: 1.82 ± 0.011	4.019PheLeu: 4.019 ± 0.021	0.771PheMet: 0.771 ± 0.007	1.351PheAsn: 1.351 ± 0.009	1.984PhePro: 1.984 ± 0.01	1.794PheGln: 1.794 ± 0.01	1.981PheArg: 1.981 ± 0.015	3.401PheSer: 3.401 ± 0.015	2.043PheThr: 2.043 ± 0.012	2.114PheVal: 2.114 ± 0.012	0.487PheTrp: 0.487 ± 0.005	1.156PheTyr: 1.156 ± 0.009	0.001PheXaa: 0.001 ± 0.0
Gly	4.461GlyAla: 4.461 ± 0.021	1.27GlyCys: 1.27 ± 0.01	3.144GlyAsp: 3.144 ± 0.014	4.208GlyGlu: 4.208 ± 0.022	2.384GlyPhe: 2.384 ± 0.015	5.05GlyGly: 5.05 ± 0.032	1.687GlyHis: 1.687 ± 0.011	2.766GlyIle: 2.766 ± 0.012	3.884GlyLys: 3.884 ± 0.02	5.833GlyLeu: 5.833 ± 0.021	1.32GlyMet: 1.32 ± 0.01	2.348GlyAsn: 2.348 ± 0.012	4.225GlyPro: 4.225 ± 0.039	2.761GlyGln: 2.761 ± 0.014	3.769GlyArg: 3.769 ± 0.018	5.791GlySer: 5.791 ± 0.026	3.573GlyThr: 3.573 ± 0.018	3.531GlyVal: 3.531 ± 0.016	0.801GlyTrp: 0.801 ± 0.008	1.731GlyTyr: 1.731 ± 0.015	0.001GlyXaa: 0.001 ± 0.0
His	1.319HisAla: 1.319 ± 0.01	0.746HisCys: 0.746 ± 0.006	0.896HisAsp: 0.896 ± 0.006	1.342HisGlu: 1.342 ± 0.009	1.071HisPhe: 1.071 ± 0.008	1.539HisGly: 1.539 ± 0.01	0.911HisHis: 0.911 ± 0.009	1.258HisIle: 1.258 ± 0.008	1.298HisLys: 1.298 ± 0.01	2.937HisLeu: 2.937 ± 0.013	0.593HisMet: 0.593 ± 0.006	0.874HisAsn: 0.874 ± 0.006	1.654HisPro: 1.654 ± 0.01	1.351HisGln: 1.351 ± 0.012	1.594HisArg: 1.594 ± 0.01	2.319HisSer: 2.319 ± 0.013	1.565HisThr: 1.565 ± 0.013	1.485HisVal: 1.485 ± 0.008	0.349HisTrp: 0.349 ± 0.004	0.804HisTyr: 0.804 ± 0.006	0.0HisXaa: 0.0 ± 0.0
Ile	2.578IleAla: 2.578 ± 0.013	1.08IleCys: 1.08 ± 0.008	2.029IleAsp: 2.029 ± 0.012	2.635IleGlu: 2.635 ± 0.014	1.885IlePhe: 1.885 ± 0.012	2.21IleGly: 2.21 ± 0.012	1.402IleHis: 1.402 ± 0.011	2.384IleIle: 2.384 ± 0.012	2.688IleLys: 2.688 ± 0.018	4.546IleLeu: 4.546 ± 0.018	0.996IleMet: 0.996 ± 0.008	1.856IleAsn: 1.856 ± 0.009	2.618IlePro: 2.618 ± 0.012	2.322IleGln: 2.322 ± 0.013	2.385IleArg: 2.385 ± 0.011	3.714IleSer: 3.714 ± 0.016	2.58IleThr: 2.58 ± 0.02	2.493IleVal: 2.493 ± 0.017	0.508IleTrp: 0.508 ± 0.005	1.377IleTyr: 1.377 ± 0.009	0.0IleXaa: 0.0 ± 0.0
Lys	4.047LysAla: 4.047 ± 0.022	1.205LysCys: 1.205 ± 0.01	3.212LysAsp: 3.212 ± 0.019	5.227LysGlu: 5.227 ± 0.026	1.739LysPhe: 1.739 ± 0.01	3.263LysGly: 3.263 ± 0.021	1.432LysHis: 1.432 ± 0.01	2.866LysIle: 2.866 ± 0.016	4.796LysLys: 4.796 ± 0.024	5.214LysLeu: 5.214 ± 0.021	1.456LysMet: 1.456 ± 0.01	2.462LysAsn: 2.462 ± 0.014	3.197LysPro: 3.197 ± 0.022	2.639LysGln: 2.639 ± 0.015	3.338LysArg: 3.338 ± 0.015	3.952LysSer: 3.952 ± 0.021	3.153LysThr: 3.153 ± 0.014	3.514LysVal: 3.514 ± 0.024	0.616LysTrp: 0.616 ± 0.006	1.582LysTyr: 1.582 ± 0.013	0.0LysXaa: 0.0 ± 0.0
Leu	6.701LeuAla: 6.701 ± 0.028	2.188LeuCys: 2.188 ± 0.012	4.699LeuAsp: 4.699 ± 0.017	7.236LeuGlu: 7.236 ± 0.027	3.349LeuPhe: 3.349 ± 0.018	5.815LeuGly: 5.815 ± 0.025	2.713LeuHis: 2.713 ± 0.013	3.858LeuIle: 3.858 ± 0.016	5.873LeuLys: 5.873 ± 0.023	10.703LeuLeu: 10.703 ± 0.044	2.01LeuMet: 2.01 ± 0.01	3.503LeuAsn: 3.503 ± 0.014	5.999LeuPro: 5.999 ± 0.021	5.808LeuGln: 5.808 ± 0.031	5.879LeuArg: 5.879 ± 0.026	7.949LeuSer: 7.949 ± 0.023	5.072LeuThr: 5.072 ± 0.017	5.442LeuVal: 5.442 ± 0.02	1.142LeuTrp: 1.142 ± 0.009	2.526LeuTyr: 2.526 ± 0.012	0.001LeuXaa: 0.001 ± 0.0
Met	1.922MetAla: 1.922 ± 0.01	0.396MetCys: 0.396 ± 0.005	1.256MetAsp: 1.256 ± 0.008	1.887MetGlu: 1.887 ± 0.011	0.72MetPhe: 0.72 ± 0.007	1.293MetGly: 1.293 ± 0.009	0.472MetHis: 0.472 ± 0.005	0.849MetIle: 0.849 ± 0.006	1.471MetLys: 1.471 ± 0.009	1.96MetLeu: 1.96 ± 0.012	0.568MetMet: 0.568 ± 0.006	0.914MetAsn: 0.914 ± 0.008	1.11MetPro: 1.11 ± 0.01	0.924MetGln: 0.924 ± 0.006	1.043MetArg: 1.043 ± 0.007	1.558MetSer: 1.558 ± 0.009	1.127MetThr: 1.127 ± 0.008	1.383MetVal: 1.383 ± 0.008	0.244MetTrp: 0.244 ± 0.003	0.558MetTyr: 0.558 ± 0.005	0.0MetXaa: 0.0 ± 0.0
Asn	2.063AsnAla: 2.063 ± 0.01	0.845AsnCys: 0.845 ± 0.008	1.542AsnAsp: 1.542 ± 0.01	2.279AsnGlu: 2.279 ± 0.013	1.484AsnPhe: 1.484 ± 0.009	2.459AsnGly: 2.459 ± 0.015	0.956AsnHis: 0.956 ± 0.007	2.133AsnIle: 2.133 ± 0.01	2.246AsnLys: 2.246 ± 0.011	3.758AsnLeu: 3.758 ± 0.015	0.914AsnMet: 0.914 ± 0.006	1.54AsnAsn: 1.54 ± 0.01	2.162AsnPro: 2.162 ± 0.01	1.676AsnGln: 1.676 ± 0.009	1.855AsnArg: 1.855 ± 0.01	3.144AsnSer: 3.144 ± 0.015	1.954AsnThr: 1.954 ± 0.01	2.217AsnVal: 2.217 ± 0.012	0.461AsnTrp: 0.461 ± 0.004	1.132AsnTyr: 1.132 ± 0.009	0.0AsnXaa: 0.0 ± 0.0
Pro	4.846ProAla: 4.846 ± 0.023	1.156ProCys: 1.156 ± 0.011	2.795ProAsp: 2.795 ± 0.014	4.462ProGlu: 4.462 ± 0.019	1.906ProPhe: 1.906 ± 0.01	5.253ProGly: 5.253 ± 0.042	1.441ProHis: 1.441 ± 0.01	1.912ProIle: 1.912 ± 0.014	2.808ProLys: 2.808 ± 0.022	5.215ProLeu: 5.215 ± 0.018	1.036ProMet: 1.036 ± 0.007	1.815ProAsn: 1.815 ± 0.012	6.077ProPro: 6.077 ± 0.042	2.833ProGln: 2.833 ± 0.015	3.337ProArg: 3.337 ± 0.019	5.693ProSer: 5.693 ± 0.024	3.147ProThr: 3.147 ± 0.018	3.815ProVal: 3.815 ± 0.02	0.703ProTrp: 0.703 ± 0.007	1.558ProTyr: 1.558 ± 0.012	0.001ProXaa: 0.001 ± 0.0
Gln	3.53GlnAla: 3.53 ± 0.018	0.963GlnCys: 0.963 ± 0.009	2.333GlnAsp: 2.333 ± 0.013	3.955GlnGlu: 3.955 ± 0.023	1.384GlnPhe: 1.384 ± 0.008	2.846GlnGly: 2.846 ± 0.014	1.307GlnHis: 1.307 ± 0.009	1.988GlnIle: 1.988 ± 0.011	2.993GlnLys: 2.993 ± 0.014	4.73GlnLeu: 4.73 ± 0.027	1.12GlnMet: 1.12 ± 0.008	1.871GlnAsn: 1.871 ± 0.01	2.809GlnPro: 2.809 ± 0.018	3.115GlnGln: 3.115 ± 0.031	2.977GlnArg: 2.977 ± 0.019	3.146GlnSer: 3.146 ± 0.017	2.291GlnThr: 2.291 ± 0.012	2.825GlnVal: 2.825 ± 0.013	0.554GlnTrp: 0.554 ± 0.005	1.149GlnTyr: 1.149 ± 0.008	0.0GlnXaa: 0.0 ± 0.0
Arg	3.815ArgAla: 3.815 ± 0.016	1.245ArgCys: 1.245 ± 0.011	2.757ArgAsp: 2.757 ± 0.013	4.009ArgGlu: 4.009 ± 0.018	1.843ArgPhe: 1.843 ± 0.009	3.619ArgGly: 3.619 ± 0.022	1.543ArgHis: 1.543 ± 0.01	2.467ArgIle: 2.467 ± 0.012	3.695ArgLys: 3.695 ± 0.016	5.403ArgLeu: 5.403 ± 0.022	1.208ArgMet: 1.208 ± 0.007	2.136ArgAsn: 2.136 ± 0.01	3.227ArgPro: 3.227 ± 0.016	2.626ArgGln: 2.626 ± 0.017	4.321ArgArg: 4.321 ± 0.025	4.258ArgSer: 4.258 ± 0.025	2.832ArgThr: 2.832 ± 0.012	3.155ArgVal: 3.155 ± 0.017	0.71ArgTrp: 0.71 ± 0.005	1.436ArgTyr: 1.436 ± 0.009	0.0ArgXaa: 0.0 ± 0.0
Ser	5.299SerAla: 5.299 ± 0.02	1.856SerCys: 1.856 ± 0.013	3.905SerAsp: 3.905 ± 0.017	5.22SerGlu: 5.22 ± 0.021	3.042SerPhe: 3.042 ± 0.013	5.604SerGly: 5.604 ± 0.024	2.142SerHis: 2.142 ± 0.011	3.223SerIle: 3.223 ± 0.012	4.12SerLys: 4.12 ± 0.019	8.188SerLeu: 8.188 ± 0.026	1.607SerMet: 1.607 ± 0.01	2.72SerAsn: 2.72 ± 0.011	6.006SerPro: 6.006 ± 0.029	3.882SerGln: 3.882 ± 0.02	4.541SerArg: 4.541 ± 0.022	9.359SerSer: 9.359 ± 0.046	4.483SerThr: 4.483 ± 0.022	4.852SerVal: 4.852 ± 0.017	1.086SerTrp: 1.086 ± 0.009	2.05SerTyr: 2.05 ± 0.012	0.001SerXaa: 0.001 ± 0.0
Thr	3.765ThrAla: 3.765 ± 0.018	1.306ThrCys: 1.306 ± 0.012	2.475ThrAsp: 2.475 ± 0.011	3.546ThrGlu: 3.546 ± 0.016	2.094ThrPhe: 2.094 ± 0.01	3.605ThrGly: 3.605 ± 0.02	1.338ThrHis: 1.338 ± 0.009	2.4ThrIle: 2.4 ± 0.016	2.692ThrLys: 2.692 ± 0.018	5.277ThrLeu: 5.277 ± 0.018	1.116ThrMet: 1.116 ± 0.008	1.755ThrAsn: 1.755 ± 0.011	3.6ThrPro: 3.6 ± 0.021	2.299ThrGln: 2.299 ± 0.011	2.485ThrArg: 2.485 ± 0.011	4.658ThrSer: 4.658 ± 0.025	3.065ThrThr: 3.065 ± 0.028	3.826ThrVal: 3.826 ± 0.023	0.707ThrTrp: 0.707 ± 0.008	1.414ThrTyr: 1.414 ± 0.01	0.0ThrXaa: 0.0 ± 0.0
Val	4.244ValAla: 4.244 ± 0.016	1.431ValCys: 1.431 ± 0.011	2.954ValAsp: 2.954 ± 0.016	3.875ValGlu: 3.875 ± 0.019	2.377ValPhe: 2.377 ± 0.012	3.383ValGly: 3.383 ± 0.016	1.56ValHis: 1.56 ± 0.009	2.897ValIle: 2.897 ± 0.015	3.438ValLys: 3.438 ± 0.02	6.106ValLeu: 6.106 ± 0.02	1.308ValMet: 1.308 ± 0.009	2.291ValAsn: 2.291 ± 0.012	3.629ValPro: 3.629 ± 0.02	2.724ValGln: 2.724 ± 0.013	3.021ValArg: 3.021 ± 0.014	4.855ValSer: 4.855 ± 0.021	3.789ValThr: 3.789 ± 0.032	3.942ValVal: 3.942 ± 0.02	0.719ValTrp: 0.719 ± 0.006	1.597ValTyr: 1.597 ± 0.009	0.0ValXaa: 0.0 ± 0.0
Trp	0.805TrpAla: 0.805 ± 0.007	0.254TrpCys: 0.254 ± 0.004	0.651TrpAsp: 0.651 ± 0.007	0.827TrpGlu: 0.827 ± 0.006	0.443TrpPhe: 0.443 ± 0.005	0.736TrpGly: 0.736 ± 0.008	0.31TrpHis: 0.31 ± 0.004	0.549TrpIle: 0.549 ± 0.005	0.812TrpLys: 0.812 ± 0.007	1.218TrpLeu: 1.218 ± 0.008	0.317TrpMet: 0.317 ± 0.004	0.542TrpAsn: 0.542 ± 0.006	0.539TrpPro: 0.539 ± 0.006	0.544TrpGln: 0.544 ± 0.005	0.741TrpArg: 0.741 ± 0.007	0.892TrpSer: 0.892 ± 0.008	0.678TrpThr: 0.678 ± 0.007	0.696TrpVal: 0.696 ± 0.005	0.197TrpTrp: 0.197 ± 0.003	0.341TrpTyr: 0.341 ± 0.005	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.386TyrAla: 1.386 ± 0.008	0.677TyrCys: 0.677 ± 0.005	1.281TyrAsp: 1.281 ± 0.011	1.736TyrGlu: 1.736 ± 0.011	1.19TyrPhe: 1.19 ± 0.008	1.645TyrGly: 1.645 ± 0.012	0.754TyrHis: 0.754 ± 0.006	1.378TyrIle: 1.378 ± 0.012	1.542TyrLys: 1.542 ± 0.016	2.614TyrLeu: 2.614 ± 0.013	0.592TyrMet: 0.592 ± 0.006	1.1TyrAsn: 1.1 ± 0.007	1.286TyrPro: 1.286 ± 0.009	1.275TyrGln: 1.275 ± 0.008	1.62TyrArg: 1.62 ± 0.01	2.166TyrSer: 2.166 ± 0.011	1.448TyrThr: 1.448 ± 0.012	1.558TyrVal: 1.558 ± 0.009	0.364TyrTrp: 0.364 ± 0.005	0.933TyrTyr: 0.933 ± 0.008	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.001XaaCys: 0.001 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.001XaaLys: 0.001 ± 0.0	0.001XaaLeu: 0.001 ± 0.0	0.001XaaMet: 0.001 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.001XaaPro: 0.001 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.001XaaSer: 0.001 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.219XaaXaa: 0.219 ± 0.028

Statistics based on 44722 proteins (24124234 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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