Amino acid dipepetide frequency for Neolentinus lepideus HHB14362 ss-1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.032AlaAla: 8.032 ± 0.058	1.114AlaCys: 1.114 ± 0.017	4.072AlaAsp: 4.072 ± 0.028	4.773AlaGlu: 4.773 ± 0.038	3.15AlaPhe: 3.15 ± 0.03	5.405AlaGly: 5.405 ± 0.035	1.962AlaHis: 1.962 ± 0.022	4.081AlaIle: 4.081 ± 0.029	3.841AlaLys: 3.841 ± 0.034	8.237AlaLeu: 8.237 ± 0.045	1.961AlaMet: 1.961 ± 0.02	2.679AlaAsn: 2.679 ± 0.027	4.96AlaPro: 4.96 ± 0.044	3.238AlaGln: 3.238 ± 0.03	5.175AlaArg: 5.175 ± 0.04	7.605AlaSer: 7.605 ± 0.047	4.975AlaThr: 4.975 ± 0.039	5.57AlaVal: 5.57 ± 0.036	1.182AlaTrp: 1.182 ± 0.02	2.296AlaTyr: 2.296 ± 0.023	0.0AlaXaa: 0.0 ± 0.0
Cys	1.03CysAla: 1.03 ± 0.015	0.276CysCys: 0.276 ± 0.007	0.693CysAsp: 0.693 ± 0.013	0.611CysGlu: 0.611 ± 0.011	0.546CysPhe: 0.546 ± 0.01	0.924CysGly: 0.924 ± 0.016	0.395CysHis: 0.395 ± 0.01	0.759CysIle: 0.759 ± 0.014	0.558CysLys: 0.558 ± 0.013	1.352CysLeu: 1.352 ± 0.018	0.321CysMet: 0.321 ± 0.008	0.418CysAsn: 0.418 ± 0.011	0.811CysPro: 0.811 ± 0.014	0.448CysGln: 0.448 ± 0.009	0.861CysArg: 0.861 ± 0.014	1.056CysSer: 1.056 ± 0.018	0.779CysThr: 0.779 ± 0.013	0.861CysVal: 0.861 ± 0.013	0.225CysTrp: 0.225 ± 0.007	0.388CysTyr: 0.388 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	4.765AspAla: 4.765 ± 0.028	0.628AspCys: 0.628 ± 0.011	3.995AspAsp: 3.995 ± 0.035	4.402AspGlu: 4.402 ± 0.039	2.022AspPhe: 2.022 ± 0.023	3.839AspGly: 3.839 ± 0.027	1.225AspHis: 1.225 ± 0.016	3.034AspIle: 3.034 ± 0.026	2.216AspLys: 2.216 ± 0.022	5.007AspLeu: 5.007 ± 0.032	1.286AspMet: 1.286 ± 0.015	1.675AspAsn: 1.675 ± 0.018	3.419AspPro: 3.419 ± 0.025	1.611AspGln: 1.611 ± 0.019	3.018AspArg: 3.018 ± 0.03	3.974AspSer: 3.974 ± 0.034	2.885AspThr: 2.885 ± 0.024	4.137AspVal: 4.137 ± 0.028	0.897AspTrp: 0.897 ± 0.014	1.537AspTyr: 1.537 ± 0.02	0.0AspXaa: 0.0 ± 0.0
Glu	4.94GluAla: 4.94 ± 0.036	0.696GluCys: 0.696 ± 0.014	4.253GluAsp: 4.253 ± 0.035	5.691GluGlu: 5.691 ± 0.061	1.832GluPhe: 1.832 ± 0.022	3.888GluGly: 3.888 ± 0.034	1.435GluHis: 1.435 ± 0.016	2.817GluIle: 2.817 ± 0.026	3.29GluLys: 3.29 ± 0.033	5.219GluLeu: 5.219 ± 0.04	1.385GluMet: 1.385 ± 0.015	1.916GluAsn: 1.916 ± 0.018	2.684GluPro: 2.684 ± 0.028	2.248GluGln: 2.248 ± 0.022	4.104GluArg: 4.104 ± 0.039	4.114GluSer: 4.114 ± 0.031	3.108GluThr: 3.108 ± 0.022	3.851GluVal: 3.851 ± 0.031	0.981GluTrp: 0.981 ± 0.014	1.703GluTyr: 1.703 ± 0.018	0.0GluXaa: 0.0 ± 0.0
Phe	3.012PheAla: 3.012 ± 0.028	0.556PheCys: 0.556 ± 0.012	2.182PheAsp: 2.182 ± 0.023	1.963PheGlu: 1.963 ± 0.02	1.455PhePhe: 1.455 ± 0.02	2.67PheGly: 2.67 ± 0.028	0.894PheHis: 0.894 ± 0.013	1.784PheIle: 1.784 ± 0.019	1.448PheLys: 1.448 ± 0.019	3.47PheLeu: 3.47 ± 0.032	0.779PheMet: 0.779 ± 0.013	1.282PheAsn: 1.282 ± 0.015	2.025PhePro: 2.025 ± 0.021	1.24PheGln: 1.24 ± 0.017	1.944PheArg: 1.944 ± 0.023	3.009PheSer: 3.009 ± 0.027	2.135PheThr: 2.135 ± 0.021	2.479PheVal: 2.479 ± 0.021	0.597PheTrp: 0.597 ± 0.012	1.044PheTyr: 1.044 ± 0.014	0.0PheXaa: 0.0 ± 0.0
Gly	5.015GlyAla: 5.015 ± 0.037	0.885GlyCys: 0.885 ± 0.014	3.381GlyAsp: 3.381 ± 0.026	3.621GlyGlu: 3.621 ± 0.032	2.45GlyPhe: 2.45 ± 0.026	5.167GlyGly: 5.167 ± 0.051	1.675GlyHis: 1.675 ± 0.021	3.252GlyIle: 3.252 ± 0.026	3.361GlyLys: 3.361 ± 0.033	5.714GlyLeu: 5.714 ± 0.033	1.565GlyMet: 1.565 ± 0.019	2.157GlyAsn: 2.157 ± 0.025	3.335GlyPro: 3.335 ± 0.03	2.317GlyGln: 2.317 ± 0.023	4.243GlyArg: 4.243 ± 0.031	5.532GlySer: 5.532 ± 0.038	3.891GlyThr: 3.891 ± 0.032	4.355GlyVal: 4.355 ± 0.034	1.15GlyTrp: 1.15 ± 0.017	1.971GlyTyr: 1.971 ± 0.021	0.0GlyXaa: 0.0 ± 0.0
His	2.013HisAla: 2.013 ± 0.02	0.388HisCys: 0.388 ± 0.01	1.299HisAsp: 1.299 ± 0.016	1.292HisGlu: 1.292 ± 0.018	0.942HisPhe: 0.942 ± 0.015	1.633HisGly: 1.633 ± 0.02	0.846HisHis: 0.846 ± 0.015	1.312HisIle: 1.312 ± 0.015	0.895HisLys: 0.895 ± 0.014	2.574HisLeu: 2.574 ± 0.024	0.511HisMet: 0.511 ± 0.009	0.789HisAsn: 0.789 ± 0.013	1.909HisPro: 1.909 ± 0.022	0.866HisGln: 0.866 ± 0.014	1.678HisArg: 1.678 ± 0.019	2.12HisSer: 2.12 ± 0.026	1.444HisThr: 1.444 ± 0.015	1.655HisVal: 1.655 ± 0.019	0.366HisTrp: 0.366 ± 0.009	0.72HisTyr: 0.72 ± 0.011	0.0HisXaa: 0.0 ± 0.0
Ile	4.055IleAla: 4.055 ± 0.03	0.792IleCys: 0.792 ± 0.013	2.712IleAsp: 2.712 ± 0.026	2.669IleGlu: 2.669 ± 0.025	1.857IlePhe: 1.857 ± 0.021	2.968IleGly: 2.968 ± 0.026	1.254IleHis: 1.254 ± 0.015	2.473IleIle: 2.473 ± 0.027	2.033IleLys: 2.033 ± 0.024	4.68IleLeu: 4.68 ± 0.034	1.003IleMet: 1.003 ± 0.014	1.598IleAsn: 1.598 ± 0.018	3.198IlePro: 3.198 ± 0.026	1.796IleGln: 1.796 ± 0.021	2.9IleArg: 2.9 ± 0.029	3.895IleSer: 3.895 ± 0.031	2.771IleThr: 2.771 ± 0.026	3.368IleVal: 3.368 ± 0.028	0.789IleTrp: 0.789 ± 0.013	1.381IleTyr: 1.381 ± 0.017	0.0IleXaa: 0.0 ± 0.0
Lys	4.092LysAla: 4.092 ± 0.031	0.54LysCys: 0.54 ± 0.01	2.572LysAsp: 2.572 ± 0.026	3.312LysGlu: 3.312 ± 0.035	1.329LysPhe: 1.329 ± 0.019	2.928LysGly: 2.928 ± 0.027	1.103LysHis: 1.103 ± 0.016	2.047LysIle: 2.047 ± 0.022	2.984LysLys: 2.984 ± 0.038	3.86LysLeu: 3.86 ± 0.031	0.957LysMet: 0.957 ± 0.014	1.421LysAsn: 1.421 ± 0.018	2.482LysPro: 2.482 ± 0.025	1.61LysGln: 1.61 ± 0.021	3.404LysArg: 3.404 ± 0.031	3.259LysSer: 3.259 ± 0.027	2.611LysThr: 2.611 ± 0.026	2.838LysVal: 2.838 ± 0.027	0.693LysTrp: 0.693 ± 0.012	1.308LysTyr: 1.308 ± 0.019	0.0LysXaa: 0.0 ± 0.0
Leu	7.919LeuAla: 7.919 ± 0.043	1.362LeuCys: 1.362 ± 0.015	5.191LeuAsp: 5.191 ± 0.034	5.371LeuGlu: 5.371 ± 0.043	3.349LeuPhe: 3.349 ± 0.03	5.707LeuGly: 5.707 ± 0.04	2.529LeuHis: 2.529 ± 0.021	3.986LeuIle: 3.986 ± 0.03	4.041LeuLys: 4.041 ± 0.03	8.814LeuLeu: 8.814 ± 0.059	1.85LeuMet: 1.85 ± 0.022	3.031LeuAsn: 3.031 ± 0.025	6.147LeuPro: 6.147 ± 0.042	3.735LeuGln: 3.735 ± 0.029	6.139LeuArg: 6.139 ± 0.042	8.213LeuSer: 8.213 ± 0.046	5.232LeuThr: 5.232 ± 0.032	5.935LeuVal: 5.935 ± 0.035	1.306LeuTrp: 1.306 ± 0.018	2.505LeuTyr: 2.505 ± 0.028	0.0LeuXaa: 0.0 ± 0.0
Met	1.951MetAla: 1.951 ± 0.021	0.278MetCys: 0.278 ± 0.007	1.265MetAsp: 1.265 ± 0.016	1.268MetGlu: 1.268 ± 0.017	0.756MetPhe: 0.756 ± 0.014	1.332MetGly: 1.332 ± 0.017	0.561MetHis: 0.561 ± 0.01	0.962MetIle: 0.962 ± 0.014	1.013MetLys: 1.013 ± 0.014	1.889MetLeu: 1.889 ± 0.02	0.534MetMet: 0.534 ± 0.011	0.767MetAsn: 0.767 ± 0.012	1.376MetPro: 1.376 ± 0.015	0.882MetGln: 0.882 ± 0.016	1.329MetArg: 1.329 ± 0.019	2.143MetSer: 2.143 ± 0.021	1.327MetThr: 1.327 ± 0.017	1.286MetVal: 1.286 ± 0.018	0.298MetTrp: 0.298 ± 0.008	0.591MetTyr: 0.591 ± 0.012	0.0MetXaa: 0.0 ± 0.0
Asn	2.969AsnAla: 2.969 ± 0.026	0.401AsnCys: 0.401 ± 0.01	1.741AsnAsp: 1.741 ± 0.019	1.74AsnGlu: 1.74 ± 0.019	1.208AsnPhe: 1.208 ± 0.016	2.582AsnGly: 2.582 ± 0.031	0.775AsnHis: 0.775 ± 0.012	1.9AsnIle: 1.9 ± 0.021	1.314AsnLys: 1.314 ± 0.017	3.001AsnLeu: 3.001 ± 0.029	0.751AsnMet: 0.751 ± 0.012	1.205AsnAsn: 1.205 ± 0.017	2.222AsnPro: 2.222 ± 0.024	1.108AsnGln: 1.108 ± 0.016	1.772AsnArg: 1.772 ± 0.019	2.509AsnSer: 2.509 ± 0.026	1.972AsnThr: 1.972 ± 0.022	2.419AsnVal: 2.419 ± 0.023	0.497AsnTrp: 0.497 ± 0.01	0.928AsnTyr: 0.928 ± 0.017	0.0AsnXaa: 0.0 ± 0.0
Pro	5.348ProAla: 5.348 ± 0.049	0.587ProCys: 0.587 ± 0.014	3.266ProAsp: 3.266 ± 0.028	3.77ProGlu: 3.77 ± 0.032	2.161ProPhe: 2.161 ± 0.024	3.75ProGly: 3.75 ± 0.035	1.562ProHis: 1.562 ± 0.02	2.657ProIle: 2.657 ± 0.025	2.491ProLys: 2.491 ± 0.027	5.32ProLeu: 5.32 ± 0.033	1.16ProMet: 1.16 ± 0.015	2.093ProAsn: 2.093 ± 0.022	6.073ProPro: 6.073 ± 0.078	2.238ProGln: 2.238 ± 0.028	3.638ProArg: 3.638 ± 0.03	7.232ProSer: 7.232 ± 0.063	4.16ProThr: 4.16 ± 0.036	4.065ProVal: 4.065 ± 0.033	0.74ProTrp: 0.74 ± 0.013	1.666ProTyr: 1.666 ± 0.021	0.0ProXaa: 0.0 ± 0.0
Gln	3.212GlnAla: 3.212 ± 0.03	0.498GlnCys: 0.498 ± 0.011	1.964GlnAsp: 1.964 ± 0.02	2.231GlnGlu: 2.231 ± 0.025	1.194GlnPhe: 1.194 ± 0.017	2.187GlnGly: 2.187 ± 0.022	1.002GlnHis: 1.002 ± 0.015	1.72GlnIle: 1.72 ± 0.018	1.643GlnLys: 1.643 ± 0.021	3.321GlnLeu: 3.321 ± 0.028	0.856GlnMet: 0.856 ± 0.014	1.312GlnAsn: 1.312 ± 0.016	2.272GlnPro: 2.272 ± 0.028	1.808GlnGln: 1.808 ± 0.034	2.423GlnArg: 2.423 ± 0.022	3.06GlnSer: 3.06 ± 0.029	2.172GlnThr: 2.172 ± 0.02	2.245GlnVal: 2.245 ± 0.021	0.542GlnTrp: 0.542 ± 0.011	1.144GlnTyr: 1.144 ± 0.016	0.0GlnXaa: 0.0 ± 0.0
Arg	5.015ArgAla: 5.015 ± 0.032	0.899ArgCys: 0.899 ± 0.013	3.331ArgAsp: 3.331 ± 0.033	3.924ArgGlu: 3.924 ± 0.032	2.122ArgPhe: 2.122 ± 0.022	3.717ArgGly: 3.717 ± 0.034	1.643ArgHis: 1.643 ± 0.017	3.019ArgIle: 3.019 ± 0.026	3.396ArgLys: 3.396 ± 0.031	5.822ArgLeu: 5.822 ± 0.035	1.428ArgMet: 1.428 ± 0.017	2.098ArgAsn: 2.098 ± 0.02	3.761ArgPro: 3.761 ± 0.03	2.417ArgGln: 2.417 ± 0.024	5.505ArgArg: 5.505 ± 0.049	5.302ArgSer: 5.302 ± 0.039	3.679ArgThr: 3.679 ± 0.029	3.795ArgVal: 3.795 ± 0.026	1.019ArgTrp: 1.019 ± 0.014	1.731ArgTyr: 1.731 ± 0.019	0.0ArgXaa: 0.0 ± 0.0
Ser	7.093SerAla: 7.093 ± 0.05	1.039SerCys: 1.039 ± 0.018	4.422SerAsp: 4.422 ± 0.033	4.194SerGlu: 4.194 ± 0.03	3.041SerPhe: 3.041 ± 0.024	5.652SerGly: 5.652 ± 0.039	2.137SerHis: 2.137 ± 0.025	4.015SerIle: 4.015 ± 0.031	3.528SerLys: 3.528 ± 0.033	7.988SerLeu: 7.988 ± 0.045	1.856SerMet: 1.856 ± 0.02	2.758SerAsn: 2.758 ± 0.025	6.291SerPro: 6.291 ± 0.06	3.191SerGln: 3.191 ± 0.027	5.461SerArg: 5.461 ± 0.039	10.167SerSer: 10.167 ± 0.097	6.011SerThr: 6.011 ± 0.052	5.26SerVal: 5.26 ± 0.031	1.141SerTrp: 1.141 ± 0.015	2.188SerTyr: 2.188 ± 0.027	0.0SerXaa: 0.0 ± 0.0
Thr	5.017ThrAla: 5.017 ± 0.034	0.775ThrCys: 0.775 ± 0.014	2.768ThrAsp: 2.768 ± 0.027	2.915ThrGlu: 2.915 ± 0.026	2.326ThrPhe: 2.326 ± 0.022	3.847ThrGly: 3.847 ± 0.03	1.435ThrHis: 1.435 ± 0.017	2.98ThrIle: 2.98 ± 0.023	2.409ThrLys: 2.409 ± 0.024	5.746ThrLeu: 5.746 ± 0.039	1.171ThrMet: 1.171 ± 0.014	1.907ThrAsn: 1.907 ± 0.023	4.466ThrPro: 4.466 ± 0.04	2.008ThrGln: 2.008 ± 0.019	3.426ThrArg: 3.426 ± 0.024	5.805ThrSer: 5.805 ± 0.05	3.898ThrThr: 3.898 ± 0.036	3.966ThrVal: 3.966 ± 0.033	0.843ThrTrp: 0.843 ± 0.015	1.639ThrTyr: 1.639 ± 0.02	0.0ThrXaa: 0.0 ± 0.0
Val	5.436ValAla: 5.436 ± 0.032	0.931ValCys: 0.931 ± 0.013	3.855ValAsp: 3.855 ± 0.03	3.959ValGlu: 3.959 ± 0.03	2.536ValPhe: 2.536 ± 0.021	3.978ValGly: 3.978 ± 0.029	1.676ValHis: 1.676 ± 0.019	3.152ValIle: 3.152 ± 0.025	3.019ValLys: 3.019 ± 0.027	6.299ValLeu: 6.299 ± 0.036	1.41ValMet: 1.41 ± 0.018	2.228ValAsn: 2.228 ± 0.022	4.247ValPro: 4.247 ± 0.025	2.49ValGln: 2.49 ± 0.018	3.886ValArg: 3.886 ± 0.028	5.198ValSer: 5.198 ± 0.037	3.658ValThr: 3.658 ± 0.027	4.729ValVal: 4.729 ± 0.036	0.974ValTrp: 0.974 ± 0.014	1.881ValTyr: 1.881 ± 0.021	0.0ValXaa: 0.0 ± 0.0
Trp	1.143TrpAla: 1.143 ± 0.017	0.232TrpCys: 0.232 ± 0.007	0.933TrpAsp: 0.933 ± 0.014	0.911TrpGlu: 0.911 ± 0.013	0.566TrpPhe: 0.566 ± 0.011	0.891TrpGly: 0.891 ± 0.014	0.383TrpHis: 0.383 ± 0.009	0.782TrpIle: 0.782 ± 0.013	0.782TrpLys: 0.782 ± 0.011	1.387TrpLeu: 1.387 ± 0.019	0.412TrpMet: 0.412 ± 0.009	0.595TrpAsn: 0.595 ± 0.012	0.648TrpPro: 0.648 ± 0.013	0.545TrpGln: 0.545 ± 0.012	1.053TrpArg: 1.053 ± 0.014	1.111TrpSer: 1.111 ± 0.016	0.939TrpThr: 0.939 ± 0.015	0.899TrpVal: 0.899 ± 0.014	0.301TrpTrp: 0.301 ± 0.008	0.451TrpTyr: 0.451 ± 0.01	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.251TyrAla: 2.251 ± 0.025	0.431TyrCys: 0.431 ± 0.009	1.68TyrAsp: 1.68 ± 0.02	1.538TyrGlu: 1.538 ± 0.019	1.129TyrPhe: 1.129 ± 0.017	1.972TyrGly: 1.972 ± 0.021	0.757TyrHis: 0.757 ± 0.013	1.461TyrIle: 1.461 ± 0.02	1.088TyrLys: 1.088 ± 0.015	2.665TyrLeu: 2.665 ± 0.023	0.613TyrMet: 0.613 ± 0.012	1.082TyrAsn: 1.082 ± 0.016	1.651TyrPro: 1.651 ± 0.022	1.01TyrGln: 1.01 ± 0.014	1.665TyrArg: 1.665 ± 0.02	2.13TyrSer: 2.13 ± 0.021	1.698TyrThr: 1.698 ± 0.022	1.829TyrVal: 1.829 ± 0.021	0.42TyrTrp: 0.42 ± 0.01	0.915TyrTyr: 0.915 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 13108 proteins (5153932 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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