Amino acid dipepetide frequency for Sorghum bicolor (Sorghum) (Sorghum vulgare)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	13.857AlaAla: 13.857 ± 0.06	1.644AlaCys: 1.644 ± 0.012	4.313AlaAsp: 4.313 ± 0.018	4.905AlaGlu: 4.905 ± 0.022	2.939AlaPhe: 2.939 ± 0.016	6.639AlaGly: 6.639 ± 0.026	1.801AlaHis: 1.801 ± 0.011	3.529AlaIle: 3.529 ± 0.015	3.758AlaLys: 3.758 ± 0.017	7.959AlaLeu: 7.959 ± 0.027	2.202AlaMet: 2.202 ± 0.011	2.552AlaAsn: 2.552 ± 0.012	5.038AlaPro: 5.038 ± 0.027	2.548AlaGln: 2.548 ± 0.014	5.376AlaArg: 5.376 ± 0.025	7.522AlaSer: 7.522 ± 0.024	4.858AlaThr: 4.858 ± 0.021	6.684AlaVal: 6.684 ± 0.025	1.008AlaTrp: 1.008 ± 0.009	1.972AlaTyr: 1.972 ± 0.011	0.0AlaXaa: 0.0 ± 0.0
Cys	1.418CysAla: 1.418 ± 0.01	0.656CysCys: 0.656 ± 0.007	0.947CysAsp: 0.947 ± 0.009	0.834CysGlu: 0.834 ± 0.008	0.889CysPhe: 0.889 ± 0.008	1.522CysGly: 1.522 ± 0.013	0.547CysHis: 0.547 ± 0.006	0.936CysIle: 0.936 ± 0.008	0.991CysLys: 0.991 ± 0.008	1.901CysLeu: 1.901 ± 0.012	0.466CysMet: 0.466 ± 0.005	0.743CysAsn: 0.743 ± 0.007	1.135CysPro: 1.135 ± 0.01	0.622CysGln: 0.622 ± 0.007	1.36CysArg: 1.36 ± 0.009	1.964CysSer: 1.964 ± 0.012	0.982CysThr: 0.982 ± 0.008	1.164CysVal: 1.164 ± 0.009	0.284CysTrp: 0.284 ± 0.004	0.586CysTyr: 0.586 ± 0.006	0.0CysXaa: 0.0 ± 0.0
Asp	4.887AspAla: 4.887 ± 0.021	0.956AspCys: 0.956 ± 0.008	4.425AspAsp: 4.425 ± 0.029	3.847AspGlu: 3.847 ± 0.018	1.963AspPhe: 1.963 ± 0.011	4.603AspGly: 4.603 ± 0.02	1.31AspHis: 1.31 ± 0.01	2.631AspIle: 2.631 ± 0.015	2.45AspLys: 2.45 ± 0.013	4.897AspLeu: 4.897 ± 0.021	1.408AspMet: 1.408 ± 0.01	1.821AspAsn: 1.821 ± 0.011	2.744AspPro: 2.744 ± 0.014	1.609AspGln: 1.609 ± 0.01	2.692AspArg: 2.692 ± 0.014	3.697AspSer: 3.697 ± 0.017	2.307AspThr: 2.307 ± 0.013	3.863AspVal: 3.863 ± 0.018	0.687AspTrp: 0.687 ± 0.007	1.425AspTyr: 1.425 ± 0.01	0.0AspXaa: 0.0 ± 0.0
Glu	5.289GluAla: 5.289 ± 0.021	0.902GluCys: 0.902 ± 0.008	3.754GluAsp: 3.754 ± 0.019	5.572GluGlu: 5.572 ± 0.033	1.955GluPhe: 1.955 ± 0.012	3.504GluGly: 3.504 ± 0.014	1.42GluHis: 1.42 ± 0.009	2.864GluIle: 2.864 ± 0.015	3.664GluLys: 3.664 ± 0.023	5.711GluLeu: 5.711 ± 0.021	1.62GluMet: 1.62 ± 0.011	2.213GluAsn: 2.213 ± 0.013	2.35GluPro: 2.35 ± 0.012	2.26GluGln: 2.26 ± 0.013	3.481GluArg: 3.481 ± 0.018	3.723GluSer: 3.723 ± 0.018	2.574GluThr: 2.574 ± 0.013	3.985GluVal: 3.985 ± 0.018	0.719GluTrp: 0.719 ± 0.007	1.45GluTyr: 1.45 ± 0.011	0.0GluXaa: 0.0 ± 0.0
Phe	2.771PheAla: 2.771 ± 0.012	0.815PheCys: 0.815 ± 0.007	2.107PheAsp: 2.107 ± 0.011	1.836PheGlu: 1.836 ± 0.011	1.699PhePhe: 1.699 ± 0.013	2.838PheGly: 2.838 ± 0.015	1.007PheHis: 1.007 ± 0.008	1.621PheIle: 1.621 ± 0.011	1.529PheLys: 1.529 ± 0.009	3.876PheLeu: 3.876 ± 0.019	0.882PheMet: 0.882 ± 0.007	1.266PheAsn: 1.266 ± 0.011	1.879PhePro: 1.879 ± 0.012	1.273PheGln: 1.273 ± 0.01	2.029PheArg: 2.029 ± 0.011	3.235PheSer: 3.235 ± 0.014	1.736PheThr: 1.736 ± 0.011	2.61PheVal: 2.61 ± 0.013	0.521PheTrp: 0.521 ± 0.006	1.055PheTyr: 1.055 ± 0.009	0.0PheXaa: 0.0 ± 0.0
Gly	6.167GlyAla: 6.167 ± 0.025	1.495GlyCys: 1.495 ± 0.011	4.0GlyAsp: 4.0 ± 0.018	3.67GlyGlu: 3.67 ± 0.013	2.841GlyPhe: 2.841 ± 0.015	7.837GlyGly: 7.837 ± 0.051	1.873GlyHis: 1.873 ± 0.012	3.055GlyIle: 3.055 ± 0.015	3.546GlyLys: 3.546 ± 0.018	5.916GlyLeu: 5.916 ± 0.023	1.627GlyMet: 1.627 ± 0.012	2.707GlyAsn: 2.707 ± 0.016	2.911GlyPro: 2.911 ± 0.016	2.188GlyGln: 2.188 ± 0.013	4.677GlyArg: 4.677 ± 0.021	6.187GlySer: 6.187 ± 0.025	3.623GlyThr: 3.623 ± 0.018	4.64GlyVal: 4.64 ± 0.021	0.994GlyTrp: 0.994 ± 0.008	2.064GlyTyr: 2.064 ± 0.014	0.0GlyXaa: 0.0 ± 0.0
His	1.948HisAla: 1.948 ± 0.012	0.577HisCys: 0.577 ± 0.007	1.322HisAsp: 1.322 ± 0.01	1.321HisGlu: 1.321 ± 0.011	0.971HisPhe: 0.971 ± 0.008	2.216HisGly: 2.216 ± 0.012	1.157HisHis: 1.157 ± 0.013	1.122HisIle: 1.122 ± 0.009	1.008HisLys: 1.008 ± 0.008	2.593HisLeu: 2.593 ± 0.015	0.595HisMet: 0.595 ± 0.007	0.835HisAsn: 0.835 ± 0.008	1.557HisPro: 1.557 ± 0.011	1.034HisGln: 1.034 ± 0.009	1.779HisArg: 1.779 ± 0.011	1.8HisSer: 1.8 ± 0.011	1.032HisThr: 1.032 ± 0.008	1.674HisVal: 1.674 ± 0.011	0.32HisTrp: 0.32 ± 0.004	0.661HisTyr: 0.661 ± 0.006	0.0HisXaa: 0.0 ± 0.0
Ile	3.408IleAla: 3.408 ± 0.015	0.986IleCys: 0.986 ± 0.008	2.479IleAsp: 2.479 ± 0.013	2.423IleGlu: 2.423 ± 0.013	1.764IlePhe: 1.764 ± 0.013	2.975IleGly: 2.975 ± 0.015	1.121IleHis: 1.121 ± 0.008	2.201IleIle: 2.201 ± 0.014	2.194IleLys: 2.194 ± 0.012	4.246IleLeu: 4.246 ± 0.017	1.008IleMet: 1.008 ± 0.008	1.63IleAsn: 1.63 ± 0.012	2.42IlePro: 2.42 ± 0.014	1.6IleGln: 1.6 ± 0.01	2.376IleArg: 2.376 ± 0.013	3.819IleSer: 3.819 ± 0.018	2.198IleThr: 2.198 ± 0.012	2.973IleVal: 2.973 ± 0.016	0.587IleTrp: 0.587 ± 0.007	1.237IleTyr: 1.237 ± 0.009	0.0IleXaa: 0.0 ± 0.0
Lys	3.861LysAla: 3.861 ± 0.018	0.866LysCys: 0.866 ± 0.008	2.752LysAsp: 2.752 ± 0.016	3.66LysGlu: 3.66 ± 0.02	1.594LysPhe: 1.594 ± 0.01	3.011LysGly: 3.011 ± 0.013	1.264LysHis: 1.264 ± 0.009	2.432LysIle: 2.432 ± 0.014	3.741LysLys: 3.741 ± 0.026	4.88LysLeu: 4.88 ± 0.024	1.276LysMet: 1.276 ± 0.009	1.968LysAsn: 1.968 ± 0.013	2.347LysPro: 2.347 ± 0.014	1.993LysGln: 1.993 ± 0.013	3.16LysArg: 3.16 ± 0.016	3.432LysSer: 3.432 ± 0.017	2.3LysThr: 2.3 ± 0.013	3.283LysVal: 3.283 ± 0.016	0.607LysTrp: 0.607 ± 0.006	1.337LysTyr: 1.337 ± 0.009	0.0LysXaa: 0.0 ± 0.0
Leu	8.094LeuAla: 8.094 ± 0.03	1.938LeuCys: 1.938 ± 0.012	5.074LeuAsp: 5.074 ± 0.021	5.652LeuGlu: 5.652 ± 0.027	3.398LeuPhe: 3.398 ± 0.015	5.921LeuGly: 5.921 ± 0.021	2.768LeuHis: 2.768 ± 0.014	3.596LeuIle: 3.596 ± 0.017	4.794LeuLys: 4.794 ± 0.021	10.583LeuLeu: 10.583 ± 0.041	2.028LeuMet: 2.028 ± 0.012	3.009LeuAsn: 3.009 ± 0.015	5.943LeuPro: 5.943 ± 0.027	4.125LeuGln: 4.125 ± 0.021	6.284LeuArg: 6.284 ± 0.024	7.834LeuSer: 7.834 ± 0.029	4.168LeuThr: 4.168 ± 0.018	6.599LeuVal: 6.599 ± 0.022	1.147LeuTrp: 1.147 ± 0.009	2.312LeuTyr: 2.312 ± 0.014	0.0LeuXaa: 0.0 ± 0.0
Met	2.645MetAla: 2.645 ± 0.013	0.388MetCys: 0.388 ± 0.004	1.473MetAsp: 1.473 ± 0.011	1.785MetGlu: 1.785 ± 0.01	0.774MetPhe: 0.774 ± 0.007	1.502MetGly: 1.502 ± 0.01	0.585MetHis: 0.585 ± 0.005	0.963MetIle: 0.963 ± 0.009	1.312MetLys: 1.312 ± 0.01	2.268MetLeu: 2.268 ± 0.012	0.686MetMet: 0.686 ± 0.006	0.829MetAsn: 0.829 ± 0.007	1.312MetPro: 1.312 ± 0.01	0.96MetGln: 0.96 ± 0.008	1.31MetArg: 1.31 ± 0.009	1.763MetSer: 1.763 ± 0.01	1.049MetThr: 1.049 ± 0.008	1.687MetVal: 1.687 ± 0.009	0.282MetTrp: 0.282 ± 0.004	0.575MetTyr: 0.575 ± 0.006	0.0MetXaa: 0.0 ± 0.0
Asn	2.576AsnAla: 2.576 ± 0.014	0.719AsnCys: 0.719 ± 0.007	1.716AsnAsp: 1.716 ± 0.009	1.911AsnGlu: 1.911 ± 0.013	1.389AsnPhe: 1.389 ± 0.01	2.795AsnGly: 2.795 ± 0.015	0.912AsnHis: 0.912 ± 0.008	1.95AsnIle: 1.95 ± 0.013	1.894AsnLys: 1.894 ± 0.013	3.606AsnLeu: 3.606 ± 0.021	0.977AsnMet: 0.977 ± 0.008	1.707AsnAsn: 1.707 ± 0.014	1.869AsnPro: 1.869 ± 0.011	1.278AsnGln: 1.278 ± 0.011	1.717AsnArg: 1.717 ± 0.011	2.896AsnSer: 2.896 ± 0.015	1.68AsnThr: 1.68 ± 0.013	2.253AsnVal: 2.253 ± 0.012	0.438AsnTrp: 0.438 ± 0.005	0.98AsnTyr: 0.98 ± 0.009	0.0AsnXaa: 0.0 ± 0.0
Pro	5.584ProAla: 5.584 ± 0.029	1.041ProCys: 1.041 ± 0.009	2.771ProAsp: 2.771 ± 0.016	3.193ProGlu: 3.193 ± 0.018	1.875ProPhe: 1.875 ± 0.011	3.439ProGly: 3.439 ± 0.017	1.296ProHis: 1.296 ± 0.011	1.914ProIle: 1.914 ± 0.012	2.302ProLys: 2.302 ± 0.013	4.653ProLeu: 4.653 ± 0.02	1.091ProMet: 1.091 ± 0.009	1.842ProAsn: 1.842 ± 0.011	5.818ProPro: 5.818 ± 0.049	1.924ProGln: 1.924 ± 0.015	3.498ProArg: 3.498 ± 0.018	5.513ProSer: 5.513 ± 0.024	2.909ProThr: 2.909 ± 0.016	3.593ProVal: 3.593 ± 0.017	0.722ProTrp: 0.722 ± 0.007	1.289ProTyr: 1.289 ± 0.011	0.0ProXaa: 0.0 ± 0.0
Gln	2.76GlnAla: 2.76 ± 0.014	0.635GlnCys: 0.635 ± 0.006	1.648GlnAsp: 1.648 ± 0.011	2.345GlnGlu: 2.345 ± 0.014	1.151GlnPhe: 1.151 ± 0.008	2.249GlnGly: 2.249 ± 0.013	1.064GlnHis: 1.064 ± 0.008	1.617GlnIle: 1.617 ± 0.01	1.889GlnLys: 1.889 ± 0.012	3.569GlnLeu: 3.569 ± 0.018	0.95GlnMet: 0.95 ± 0.008	1.329GlnAsn: 1.329 ± 0.012	1.98GlnPro: 1.98 ± 0.015	2.476GlnGln: 2.476 ± 0.028	2.328GlnArg: 2.328 ± 0.014	2.514GlnSer: 2.514 ± 0.013	1.49GlnThr: 1.49 ± 0.011	2.277GlnVal: 2.277 ± 0.011	0.469GlnTrp: 0.469 ± 0.006	0.884GlnTyr: 0.884 ± 0.007	0.0GlnXaa: 0.0 ± 0.0
Arg	5.126ArgAla: 5.126 ± 0.023	1.354ArgCys: 1.354 ± 0.008	3.001ArgAsp: 3.001 ± 0.016	3.333ArgGlu: 3.333 ± 0.015	2.225ArgPhe: 2.225 ± 0.014	4.148ArgGly: 4.148 ± 0.02	1.716ArgHis: 1.716 ± 0.012	2.572ArgIle: 2.572 ± 0.013	3.33ArgLys: 3.33 ± 0.016	5.921ArgLeu: 5.921 ± 0.024	1.462ArgMet: 1.462 ± 0.011	2.13ArgAsn: 2.13 ± 0.012	3.336ArgPro: 3.336 ± 0.017	2.124ArgGln: 2.124 ± 0.013	6.311ArgArg: 6.311 ± 0.03	5.014ArgSer: 5.014 ± 0.023	2.766ArgThr: 2.766 ± 0.014	3.722ArgVal: 3.722 ± 0.017	0.984ArgTrp: 0.984 ± 0.008	1.547ArgTyr: 1.547 ± 0.01	0.0ArgXaa: 0.0 ± 0.0
Ser	6.692SerAla: 6.692 ± 0.022	1.837SerCys: 1.837 ± 0.012	4.102SerAsp: 4.102 ± 0.02	4.032SerGlu: 4.032 ± 0.018	3.27SerPhe: 3.27 ± 0.013	6.041SerGly: 6.041 ± 0.025	1.915SerHis: 1.915 ± 0.012	3.627SerIle: 3.627 ± 0.018	3.909SerLys: 3.909 ± 0.019	7.748SerLeu: 7.748 ± 0.029	2.053SerMet: 2.053 ± 0.011	3.104SerAsn: 3.104 ± 0.018	4.994SerPro: 4.994 ± 0.028	2.549SerGln: 2.549 ± 0.015	4.83SerArg: 4.83 ± 0.024	10.463SerSer: 10.463 ± 0.046	4.58SerThr: 4.58 ± 0.018	4.995SerVal: 4.995 ± 0.018	1.155SerTrp: 1.155 ± 0.01	2.096SerTyr: 2.096 ± 0.012	0.0SerXaa: 0.0 ± 0.0
Thr	4.476ThrAla: 4.476 ± 0.02	0.997ThrCys: 0.997 ± 0.008	2.336ThrAsp: 2.336 ± 0.014	2.592ThrGlu: 2.592 ± 0.018	1.793ThrPhe: 1.793 ± 0.011	3.576ThrGly: 3.576 ± 0.017	1.021ThrHis: 1.021 ± 0.008	2.256ThrIle: 2.256 ± 0.012	2.314ThrLys: 2.314 ± 0.015	4.32ThrLeu: 4.32 ± 0.017	1.214ThrMet: 1.214 ± 0.008	1.778ThrAsn: 1.778 ± 0.012	2.921ThrPro: 2.921 ± 0.018	1.387ThrGln: 1.387 ± 0.009	2.625ThrArg: 2.625 ± 0.013	4.484ThrSer: 4.484 ± 0.018	3.389ThrThr: 3.389 ± 0.015	3.53ThrVal: 3.53 ± 0.016	0.638ThrTrp: 0.638 ± 0.006	1.297ThrTyr: 1.297 ± 0.01	0.0ThrXaa: 0.0 ± 0.0
Val	6.644ValAla: 6.644 ± 0.023	1.24ValCys: 1.24 ± 0.009	3.846ValAsp: 3.846 ± 0.017	4.027ValGlu: 4.027 ± 0.016	2.516ValPhe: 2.516 ± 0.013	4.398ValGly: 4.398 ± 0.021	1.723ValHis: 1.723 ± 0.011	2.885ValIle: 2.885 ± 0.016	3.172ValLys: 3.172 ± 0.016	6.781ValLeu: 6.781 ± 0.022	1.521ValMet: 1.521 ± 0.009	2.108ValAsn: 2.108 ± 0.012	3.889ValPro: 3.889 ± 0.017	2.349ValGln: 2.349 ± 0.012	3.748ValArg: 3.748 ± 0.019	5.107ValSer: 5.107 ± 0.019	3.409ValThr: 3.409 ± 0.015	5.659ValVal: 5.659 ± 0.024	0.83ValTrp: 0.83 ± 0.007	1.81ValTyr: 1.81 ± 0.01	0.0ValXaa: 0.0 ± 0.0
Trp	0.964TrpAla: 0.964 ± 0.009	0.282TrpCys: 0.282 ± 0.004	0.676TrpAsp: 0.676 ± 0.006	0.723TrpGlu: 0.723 ± 0.007	0.486TrpPhe: 0.486 ± 0.005	0.766TrpGly: 0.766 ± 0.007	0.321TrpHis: 0.321 ± 0.005	0.616TrpIle: 0.616 ± 0.007	0.748TrpLys: 0.748 ± 0.008	1.264TrpLeu: 1.264 ± 0.009	0.372TrpMet: 0.372 ± 0.005	0.567TrpAsn: 0.567 ± 0.006	0.629TrpPro: 0.629 ± 0.007	0.459TrpGln: 0.459 ± 0.005	1.06TrpArg: 1.06 ± 0.008	1.033TrpSer: 1.033 ± 0.009	0.667TrpThr: 0.667 ± 0.007	0.803TrpVal: 0.803 ± 0.007	0.273TrpTrp: 0.273 ± 0.004	0.336TrpTyr: 0.336 ± 0.005	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.933TyrAla: 1.933 ± 0.013	0.617TyrCys: 0.617 ± 0.007	1.481TyrAsp: 1.481 ± 0.01	1.35TyrGlu: 1.35 ± 0.009	1.094TyrPhe: 1.094 ± 0.009	2.037TyrGly: 2.037 ± 0.014	0.7TyrHis: 0.7 ± 0.007	1.257TyrIle: 1.257 ± 0.009	1.218TyrLys: 1.218 ± 0.01	2.577TyrLeu: 2.577 ± 0.015	0.71TyrMet: 0.71 ± 0.007	1.125TyrAsn: 1.125 ± 0.009	1.194TyrPro: 1.194 ± 0.011	0.87TyrGln: 0.87 ± 0.008	1.485TyrArg: 1.485 ± 0.009	1.991TyrSer: 1.991 ± 0.012	1.226TyrThr: 1.226 ± 0.01	1.666TyrVal: 1.666 ± 0.01	0.381TyrTrp: 0.381 ± 0.005	0.929TyrTyr: 0.929 ± 0.009	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 41381 proteins (16674116 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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