Proteome-pI 2.0 - Proteome Isoelectric Point Database

Shayang fly virus 4

Taxonomy: Viruses; Riboviria; unclassified Riboviria; unclassified ssRNA viruses; unclassified ssRNA positive-strand viruses

Average proteome isoelectric point is 6.87

Get precalculated fractions of proteins

Acidic

pI < 6.8

6.8-7.4

pI > 7.4

Basic

All

Virtual 2D-PAGE plot for 1 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions

Protein with the lowest isoelectric point:

>tr|A0A0N7JQI5|A0A0N7JQI5_9VIRU Non-structural protein 3 OS=Shayang fly virus 4 OX=1746061 PE=4 SV=1

MM1 pKa = 7.78SITPNASGVARR12 pKa = 11.84NANKK16 pKa = 10.11LAEE19 pKa = 4.03ARR21 pKa = 11.84ILTAAVSGQTKK32 pKa = 10.45RR33 pKa = 11.84LTDD36 pKa = 3.55EE37 pKa = 4.53AKK39 pKa = 10.87ALADD43 pKa = 4.92LANQANNAMMAVVTNMGPTVNSGIRR68 pKa = 11.84KK69 pKa = 8.87KK70 pKa = 10.78RR71 pKa = 11.84KK72 pKa = 6.82TKK74 pKa = 10.3NGKK77 pKa = 8.62GANASNGGIISGVSKK92 pKa = 9.55TIKK95 pKa = 10.44DD96 pKa = 3.3ATNNIFIITSLTLILIIAYY115 pKa = 7.96STASPLNQNTDD126 pKa = 3.29STSSNRR132 pKa = 11.84LGLQFFGKK140 pKa = 10.07DD141 pKa = 3.35FQEE144 pKa = 4.94IEE146 pKa = 4.03GKK148 pKa = 9.35IAKK151 pKa = 8.8TGLKK155 pKa = 9.87CKK157 pKa = 9.53SARR160 pKa = 11.84DD161 pKa = 3.86CTNVVVDD168 pKa = 6.32LMNADD173 pKa = 3.84QKK175 pKa = 11.55DD176 pKa = 3.84KK177 pKa = 10.5PDD179 pKa = 3.81CNILVNHH186 pKa = 6.63ATNLASIAPGKK197 pKa = 10.28SVLRR201 pKa = 11.84AKK203 pKa = 10.61LVDD206 pKa = 4.05YY207 pKa = 11.35YY208 pKa = 10.55MEE210 pKa = 5.38PLLKK214 pKa = 10.57CKK216 pKa = 10.0TDD218 pKa = 2.9IKK220 pKa = 11.12NIFLRR225 pKa = 11.84YY226 pKa = 9.4DD227 pKa = 3.76AIEE230 pKa = 4.15YY231 pKa = 10.72KK232 pKa = 10.29EE233 pKa = 4.73DD234 pKa = 3.46PVKK237 pKa = 10.74FMCYY241 pKa = 10.37LLDD244 pKa = 4.67CDD246 pKa = 3.85QKK248 pKa = 11.61SRR250 pKa = 11.84ADD252 pKa = 3.51LQVEE256 pKa = 4.39FEE258 pKa = 4.3TLKK261 pKa = 9.55TQDD264 pKa = 3.36TNTLRR269 pKa = 11.84EE270 pKa = 4.01IEE272 pKa = 4.44KK273 pKa = 10.88LLNTYY278 pKa = 11.19NDD280 pKa = 3.37MVLDD284 pKa = 3.86KK285 pKa = 10.3MVNLQISSEE294 pKa = 4.04ITDD297 pKa = 4.11KK298 pKa = 11.02FQKK301 pKa = 8.56TCKK304 pKa = 10.58DD305 pKa = 3.2NMNALNNRR313 pKa = 11.84YY314 pKa = 9.27GGRR317 pKa = 11.84YY318 pKa = 9.33GKK320 pKa = 10.1ISNLLEE326 pKa = 4.78KK327 pKa = 10.25IEE329 pKa = 4.65KK330 pKa = 8.17STKK333 pKa = 10.2NLITEE338 pKa = 4.26IEE340 pKa = 4.47SNNKK344 pKa = 9.75KK345 pKa = 10.27LDD347 pKa = 3.64NLAEE351 pKa = 4.31QIEE354 pKa = 4.35DD355 pKa = 3.17MPRR358 pKa = 11.84RR359 pKa = 11.84IKK361 pKa = 10.89RR362 pKa = 11.84EE363 pKa = 3.58TSQDD367 pKa = 2.11KK368 pKa = 9.18WANFKK373 pKa = 10.85SDD375 pKa = 2.98SQTIMTCLSKK385 pKa = 11.25LNIVCSSQATCRR397 pKa = 11.84TSINEE402 pKa = 4.12VVDD405 pKa = 3.72GLKK408 pKa = 10.84DD409 pKa = 3.46KK410 pKa = 11.13SVEE413 pKa = 4.1DD414 pKa = 3.65NQFEE418 pKa = 5.15LNFGTIKK425 pKa = 10.69DD426 pKa = 3.76LRR428 pKa = 11.84EE429 pKa = 4.3CIVTGSAVHH438 pKa = 5.89EE439 pKa = 4.71AIEE442 pKa = 4.11PKK444 pKa = 9.91INEE447 pKa = 4.06YY448 pKa = 9.81IARR451 pKa = 11.84HH452 pKa = 5.01GRR454 pKa = 11.84YY455 pKa = 8.81VSCKK459 pKa = 8.37AQVDD463 pKa = 4.25VVQANLKK470 pKa = 9.97YY471 pKa = 7.47MTGVIVDD478 pKa = 4.05DD479 pKa = 4.21VEE481 pKa = 4.45VMSEE485 pKa = 3.94KK486 pKa = 10.41RR487 pKa = 11.84CPLFLDD493 pKa = 3.7VLNEE497 pKa = 3.83KK498 pKa = 10.2YY499 pKa = 10.38IQIKK503 pKa = 10.35RR504 pKa = 11.84FGHH507 pKa = 4.51EE508 pKa = 3.9TGTKK512 pKa = 8.62IDD514 pKa = 3.9EE515 pKa = 4.32KK516 pKa = 11.18AVLIKK521 pKa = 10.54PCEE524 pKa = 4.0EE525 pKa = 3.97NKK527 pKa = 10.01NWQHH531 pKa = 6.92DD532 pKa = 3.41GWLGGNSGSCATGIDD547 pKa = 3.52KK548 pKa = 10.31TSWDD552 pKa = 3.37VRR554 pKa = 11.84EE555 pKa = 5.12CIKK558 pKa = 10.68QPYY561 pKa = 6.27GTCMHH566 pKa = 6.88KK567 pKa = 10.71KK568 pKa = 10.31SDD570 pKa = 3.96TCVLGYY576 pKa = 11.17GNVVVKK582 pKa = 10.63KK583 pKa = 10.51PNTLYY588 pKa = 10.67TNSYY592 pKa = 9.82KK593 pKa = 10.62NASNPICCTMSCFEE607 pKa = 5.5LSDD610 pKa = 4.32LYY612 pKa = 10.93LTFTNQPLCAPCIKK626 pKa = 10.54AFSTVFWGDD635 pKa = 2.8VCLKK639 pKa = 9.94HH640 pKa = 7.47VSGEE644 pKa = 3.65ISGINIYY651 pKa = 10.54SSQTVFDD658 pKa = 5.14LPDD661 pKa = 3.73HH662 pKa = 6.97SKK664 pKa = 8.79VTCPNAYY671 pKa = 9.99RR672 pKa = 11.84FNQCCAGKK680 pKa = 10.55GPAPVGSQSVFKK692 pKa = 10.74DD693 pKa = 3.77KK694 pKa = 11.61YY695 pKa = 9.21CVCSLKK701 pKa = 10.81HH702 pKa = 5.54PSWYY706 pKa = 10.5DD707 pKa = 3.26MILAKK712 pKa = 10.45INTLKK717 pKa = 11.11KK718 pKa = 9.97NVFKK722 pKa = 10.81VDD724 pKa = 3.37HH725 pKa = 6.93LIAFAILFLIFCWHH739 pKa = 6.86HH740 pKa = 5.74GLGTVLVVAYY750 pKa = 8.65LSWIVISVEE759 pKa = 4.39GACHH763 pKa = 5.84VEE765 pKa = 3.79NMVPRR770 pKa = 11.84SAIVGLSNGLPIEE783 pKa = 4.2HH784 pKa = 6.29MRR786 pKa = 11.84VRR788 pKa = 11.84PGQCFVAGDD797 pKa = 3.66ATVEE801 pKa = 3.93IVAIRR806 pKa = 11.84VFHH809 pKa = 7.04IYY811 pKa = 10.77NFLRR815 pKa = 11.84AIPYY819 pKa = 9.35KK820 pKa = 10.19IKK822 pKa = 10.27PVCQVFDD829 pKa = 3.89WGCKK833 pKa = 9.89GGMSDD838 pKa = 3.62AVYY841 pKa = 10.47NIKK844 pKa = 10.28SDD846 pKa = 3.81CYY848 pKa = 9.06NNCVPGLRR856 pKa = 11.84KK857 pKa = 9.59QIKK860 pKa = 8.91GAEE863 pKa = 4.21AEE865 pKa = 4.28WSGDD869 pKa = 2.67ACFFMGRR876 pKa = 11.84VATRR880 pKa = 11.84LDD882 pKa = 3.19VCFSYY887 pKa = 10.84GATSTFVDD895 pKa = 5.18LYY897 pKa = 11.32SRR899 pKa = 11.84ISGDD903 pKa = 3.13PHH905 pKa = 8.27IEE907 pKa = 3.93LTVKK911 pKa = 9.84FHH913 pKa = 7.22GIGFEE918 pKa = 4.43GVGHH922 pKa = 7.26ISTSSLDD929 pKa = 3.57GPEE932 pKa = 4.31KK933 pKa = 10.42IKK935 pKa = 10.47IYY937 pKa = 10.19NIRR940 pKa = 11.84AAAQLWPEE948 pKa = 4.27MISYY952 pKa = 10.52RR953 pKa = 11.84LSKK956 pKa = 9.94YY957 pKa = 9.62LCAYY961 pKa = 10.15HH962 pKa = 6.39YY963 pKa = 11.0VEE965 pKa = 5.79SANTCNSGDD974 pKa = 3.53VFKK977 pKa = 11.12PNDD980 pKa = 3.54IDD982 pKa = 4.84ADD984 pKa = 4.12CLNLQQRR991 pKa = 11.84WNIEE995 pKa = 3.64HH996 pKa = 6.98GGYY999 pKa = 9.66QVTYY1003 pKa = 8.5DD1004 pKa = 3.63TKK1006 pKa = 11.15DD1007 pKa = 3.28FEE1009 pKa = 4.58QQLHH1013 pKa = 6.21SSFVDD1018 pKa = 3.57CSLNSFINNTATTLKK1033 pKa = 10.62YY1034 pKa = 11.05YY1035 pKa = 10.36EE1036 pKa = 4.29DD1037 pKa = 3.87QVWAEE1042 pKa = 4.26FDD1044 pKa = 3.11ISSTKK1049 pKa = 9.26FTFASSVPLCLDD1061 pKa = 3.69LNSWNISAEE1070 pKa = 3.91AGITGYY1076 pKa = 10.69HH1077 pKa = 6.12RR1078 pKa = 11.84VTKK1081 pKa = 10.35IKK1083 pKa = 10.36FINAGSRR1090 pKa = 11.84CRR1092 pKa = 11.84LFFDD1096 pKa = 4.59MDD1098 pKa = 4.04DD1099 pKa = 4.04CLSTNGRR1106 pKa = 11.84LIVLGKK1112 pKa = 10.4NEE1114 pKa = 4.1GPHH1117 pKa = 6.36TIEE1120 pKa = 4.2YY1121 pKa = 8.87WCGDD1125 pKa = 3.32NSTGRR1130 pKa = 11.84AEE1132 pKa = 3.64IHH1134 pKa = 5.97LAEE1137 pKa = 5.37DD1138 pKa = 3.3KK1139 pKa = 11.68AEE1141 pKa = 3.66IRR1143 pKa = 11.84TFNILTNFVPHH1154 pKa = 7.08KK1155 pKa = 9.08NTIRR1159 pKa = 11.84NTFTRR1164 pKa = 11.84VINGGSVADD1173 pKa = 4.49LSAILSNAFDD1183 pKa = 4.29SLNLASWYY1191 pKa = 10.23HH1192 pKa = 7.0AITKK1196 pKa = 9.15FFGGFFKK1203 pKa = 10.91FGLFKK1208 pKa = 10.87LALGALLALGAWNCFVRR1225 pKa = 11.84GNMVGVFLCCLLFWLLILTDD1245 pKa = 4.79LVIATNQSHH1254 pKa = 6.95AAPIRR1259 pKa = 11.84IVSTITDD1266 pKa = 3.66MVVGLVFAVVVFVLKK1281 pKa = 10.75CPMRR1285 pKa = 11.84AALTTSFVLRR1295 pKa = 11.84TFYY1298 pKa = 10.73CSCLWFVNVVFHH1310 pKa = 4.54MHH1312 pKa = 5.71IVKK1315 pKa = 10.4FEE1317 pKa = 4.18LCLNILSEE1325 pKa = 4.35TLAVILSVWSEE1336 pKa = 3.72DD1337 pKa = 3.98RR1338 pKa = 11.84IVMLCAFSWLCYY1350 pKa = 9.84IHH1352 pKa = 7.04GKK1354 pKa = 9.38HH1355 pKa = 6.24LMCNSPVVNKK1365 pKa = 9.12GTMYY1369 pKa = 10.63LHH1371 pKa = 7.4PLTALITLKK1380 pKa = 10.78DD1381 pKa = 3.45HH1382 pKa = 5.99SEE1384 pKa = 3.56RR1385 pKa = 11.84RR1386 pKa = 11.84AIVNEE1391 pKa = 3.69ANNAHH1396 pKa = 5.96NTLDD1400 pKa = 4.1SIIDD1404 pKa = 3.79QNHH1407 pKa = 5.8HH1408 pKa = 5.79RR1409 pKa = 11.84VAGISNAFFCAPNKK1423 pKa = 10.28VKK1425 pKa = 9.88TDD1427 pKa = 3.82KK1428 pKa = 10.86IVVEE1432 pKa = 4.27IEE1434 pKa = 4.12DD1435 pKa = 4.16PLVSGGLTTIRR1446 pKa = 11.84TSKK1449 pKa = 10.72YY1450 pKa = 7.21GTVYY1454 pKa = 10.67VADD1457 pKa = 4.06INKK1460 pKa = 9.19KK1461 pKa = 9.83LCFAVMRR1468 pKa = 11.84HH1469 pKa = 4.82SVEE1472 pKa = 4.21PEE1474 pKa = 3.05ITMEE1478 pKa = 5.68DD1479 pKa = 3.9DD1480 pKa = 3.2VCYY1483 pKa = 8.64ATPAILSLIEE1493 pKa = 4.1KK1494 pKa = 8.51TAVPYY1499 pKa = 10.68SVLRR1503 pKa = 11.84CHH1505 pKa = 6.88IGEE1508 pKa = 4.48SGTAVVKK1515 pKa = 10.61DD1516 pKa = 3.75GKK1518 pKa = 10.64LQFLSGVRR1526 pKa = 11.84NGNPFFVGSVEE1537 pKa = 4.13PPKK1540 pKa = 10.77SLEE1543 pKa = 3.62IVTKK1547 pKa = 10.23VKK1549 pKa = 10.65EE1550 pKa = 4.43STSEE1554 pKa = 3.81ADD1556 pKa = 3.32PNIIKK1561 pKa = 10.73VKK1563 pKa = 10.44DD1564 pKa = 3.81PYY1566 pKa = 9.33GTEE1569 pKa = 3.78YY1570 pKa = 10.67QYY1572 pKa = 11.91SHH1574 pKa = 6.92GSLISKK1580 pKa = 9.01KK1581 pKa = 9.06IWAKK1585 pKa = 9.87HH1586 pKa = 5.0SSSKK1590 pKa = 10.65GVPLCADD1597 pKa = 3.29VQVADD1602 pKa = 4.7EE1603 pKa = 4.33STAIYY1608 pKa = 9.92SGCEE1612 pKa = 3.49KK1613 pKa = 10.57LDD1615 pKa = 3.45RR1616 pKa = 11.84KK1617 pKa = 10.4IFGVPVHH1624 pKa = 6.01SAYY1627 pKa = 9.88TFIFNKK1633 pKa = 9.07ATATCDD1639 pKa = 4.11AISCPIIGDD1648 pKa = 4.31RR1649 pKa = 11.84IWISKK1654 pKa = 9.4NIKK1657 pKa = 10.08EE1658 pKa = 4.21GLQDD1662 pKa = 3.32VAHH1665 pKa = 5.54VQKK1668 pKa = 10.89SYY1670 pKa = 11.53VFTTDD1675 pKa = 2.79KK1676 pKa = 11.16VLTSGSGIYY1685 pKa = 10.07IKK1687 pKa = 10.41VSCSRR1692 pKa = 11.84YY1693 pKa = 9.61IMISVVTKK1701 pKa = 8.84SFRR1704 pKa = 11.84MEE1706 pKa = 4.15GSDD1709 pKa = 4.34LIHH1712 pKa = 6.83YY1713 pKa = 7.46YY1714 pKa = 9.99ISRR1717 pKa = 11.84PNDD1720 pKa = 3.06CRR1722 pKa = 11.84ILTTIKK1728 pKa = 10.58NVEE1731 pKa = 3.84IEE1733 pKa = 3.98QKK1735 pKa = 10.17IRR1737 pKa = 11.84NDD1739 pKa = 3.74CADD1742 pKa = 3.68EE1743 pKa = 4.13TSPTTIVAFSHH1754 pKa = 4.82YY1755 pKa = 9.89QRR1757 pKa = 11.84GRR1759 pKa = 11.84FHH1761 pKa = 5.86ITEE1764 pKa = 5.21FIDD1767 pKa = 3.7TKK1769 pKa = 9.4EE1770 pKa = 3.98KK1771 pKa = 10.93CVMRR1775 pKa = 11.84LQATLAGVGFINKK1788 pKa = 8.69SHH1790 pKa = 6.89SDD1792 pKa = 3.42SGSDD1796 pKa = 3.37TDD1798 pKa = 4.83CGIVGQSPRR1807 pKa = 11.84KK1808 pKa = 9.54RR1809 pKa = 11.84FYY1811 pKa = 11.73DD1812 pKa = 3.45MDD1814 pKa = 3.52QSRR1817 pKa = 11.84MKK1819 pKa = 10.71KK1820 pKa = 9.28FFNRR1824 pKa = 11.84KK1825 pKa = 8.44GFTWPDD1831 pKa = 3.0RR1832 pKa = 11.84FLVDD1836 pKa = 3.26SAIRR1840 pKa = 11.84SIFQDD1845 pKa = 3.58LAKK1848 pKa = 10.45SIPEE1852 pKa = 3.94QEE1854 pKa = 4.23VMLSVGLLKK1863 pKa = 10.57EE1864 pKa = 4.1MKK1866 pKa = 9.5DD1867 pKa = 3.15RR1868 pKa = 11.84RR1869 pKa = 11.84MFSHH1873 pKa = 6.5YY1874 pKa = 9.8NWAYY1878 pKa = 10.79VSWQMLQVRR1887 pKa = 11.84NKK1889 pKa = 10.24NLEE1892 pKa = 4.33LNPDD1896 pKa = 3.64APWWKK1901 pKa = 9.88NYY1903 pKa = 10.09KK1904 pKa = 10.38GIIADD1909 pKa = 3.84TPIDD1913 pKa = 3.54HH1914 pKa = 6.71TAVDD1918 pKa = 4.29FGGDD1922 pKa = 3.47RR1923 pKa = 11.84DD1924 pKa = 3.98LVTPLMHH1931 pKa = 5.88VAAYY1935 pKa = 9.75GKK1937 pKa = 10.25AQIGYY1942 pKa = 8.16QGKK1945 pKa = 8.24VHH1947 pKa = 7.05LIVHH1951 pKa = 7.04PDD1953 pKa = 3.19PSFAKK1958 pKa = 8.75ITEE1961 pKa = 4.0ISEE1964 pKa = 4.15DD1965 pKa = 3.69NHH1967 pKa = 5.07WQIIDD1972 pKa = 3.59VPDD1975 pKa = 5.32RR1976 pKa = 11.84IPRR1979 pKa = 11.84MAKK1982 pKa = 9.8RR1983 pKa = 11.84YY1984 pKa = 8.2LHH1986 pKa = 6.06EE1987 pKa = 4.33AVSRR1991 pKa = 11.84GLRR1994 pKa = 11.84SIKK1997 pKa = 10.2ILISKK2002 pKa = 8.16PYY2004 pKa = 7.81WQEE2007 pKa = 3.74LGNEE2011 pKa = 4.14YY2012 pKa = 10.26QGEE2015 pKa = 4.06FDD2017 pKa = 4.36IPAALSLCCALWVEE2031 pKa = 4.38TEE2033 pKa = 4.14YY2034 pKa = 11.74VDD2036 pKa = 5.21DD2037 pKa = 4.35FKK2039 pKa = 11.14TYY2041 pKa = 10.47VSNGRR2046 pKa = 11.84NLSRR2050 pKa = 11.84GFLPSLKK2057 pKa = 10.53AGLTQPWHH2065 pKa = 6.03TPDD2068 pKa = 3.45EE2069 pKa = 4.16KK2070 pKa = 11.29LKK2072 pKa = 9.55VSEE2075 pKa = 4.5YY2076 pKa = 11.05GEE2078 pKa = 4.0QLLTYY2083 pKa = 10.4SNFWKK2088 pKa = 9.25RR2089 pKa = 11.84TIASGCAEE2097 pKa = 4.13PHH2099 pKa = 6.55DD2100 pKa = 4.19VLLTRR2105 pKa = 11.84TTNCNNISEE2114 pKa = 4.43ARR2116 pKa = 11.84LANKK2120 pKa = 9.75RR2121 pKa = 11.84LHH2123 pKa = 6.05ICSLRR2128 pKa = 11.84NFTSRR2133 pKa = 11.84GSCFIYY2139 pKa = 10.49DD2140 pKa = 4.01GSVVTSWHH2148 pKa = 5.33CTKK2151 pKa = 10.86GNAIRR2156 pKa = 11.84VTNCDD2161 pKa = 2.35KK2162 pKa = 11.04TMRR2165 pKa = 11.84FDD2167 pKa = 3.88APVMQSKK2174 pKa = 10.09AQDD2177 pKa = 2.89IAVYY2181 pKa = 9.98GKK2183 pKa = 10.42KK2184 pKa = 8.93LTFAKK2189 pKa = 9.75MSLGEE2194 pKa = 4.03IVVTFNPITHH2204 pKa = 6.84FGMYY2208 pKa = 9.81FVVEE2212 pKa = 4.31SLNATLEE2219 pKa = 4.19GRR2221 pKa = 11.84PGAQFAKK2228 pKa = 10.04LLPVRR2233 pKa = 11.84IDD2235 pKa = 3.22NEE2237 pKa = 4.26ANVIRR2242 pKa = 11.84VPYY2245 pKa = 10.19HH2246 pKa = 6.16HH2247 pKa = 7.33GCSGSPIVNYY2257 pKa = 10.26QGDD2260 pKa = 3.67IVGVFGLGTDD2270 pKa = 3.59VAYY2273 pKa = 7.55TTATGKK2279 pKa = 10.25ISTVAHH2285 pKa = 6.52FSPIGGLQLDD2295 pKa = 3.6SMAFFEE2301 pKa = 4.49ACARR2305 pKa = 11.84NFLEE2309 pKa = 4.57APKK2312 pKa = 10.46SGEE2315 pKa = 3.72FTACYY2320 pKa = 10.25LNAPTGSGKK2329 pKa = 6.96TTQFPLALAEE2339 pKa = 4.01EE2340 pKa = 4.91LIKK2343 pKa = 10.75RR2344 pKa = 11.84EE2345 pKa = 3.84TGMGCTHH2352 pKa = 7.65ILICQPNVDD2361 pKa = 3.83AVKK2364 pKa = 10.86NGAKK2368 pKa = 9.93RR2369 pKa = 11.84AATAATSMGFKK2380 pKa = 10.02KK2381 pKa = 10.62LKK2383 pKa = 9.7ISYY2386 pKa = 8.62TVGIGNEE2393 pKa = 4.01DD2394 pKa = 3.27SDD2396 pKa = 5.6LVMLEE2401 pKa = 3.86CDD2403 pKa = 3.18RR2404 pKa = 11.84PTVHH2408 pKa = 7.82IEE2410 pKa = 3.52FKK2412 pKa = 10.52TYY2414 pKa = 9.57GKK2416 pKa = 9.87QWANLAQIEE2425 pKa = 4.51EE2426 pKa = 4.22YY2427 pKa = 10.7QYY2429 pKa = 10.94IILDD2433 pKa = 3.92EE2434 pKa = 4.14VHH2436 pKa = 6.86VIGDD2440 pKa = 3.88EE2441 pKa = 4.19NVVAMMVHH2449 pKa = 6.73IEE2451 pKa = 4.22TKK2453 pKa = 7.71YY2454 pKa = 9.5HH2455 pKa = 6.36KK2456 pKa = 10.24SNKK2459 pKa = 8.53GVLYY2463 pKa = 10.03MSATHH2468 pKa = 6.9ISNANLYY2475 pKa = 10.18DD2476 pKa = 3.63VAQGEE2481 pKa = 4.71TIAGSPHH2488 pKa = 7.13NITCEE2493 pKa = 3.42SWTIVTDD2500 pKa = 3.88KK2501 pKa = 10.93SDD2503 pKa = 3.65SNAPEE2508 pKa = 3.9GLRR2511 pKa = 11.84NKK2513 pKa = 10.38SRR2515 pKa = 11.84VDD2517 pKa = 3.24RR2518 pKa = 11.84TAGKK2522 pKa = 9.58LHH2524 pKa = 6.68LCSDD2528 pKa = 4.63VIKK2531 pKa = 10.53HH2532 pKa = 5.98KK2533 pKa = 10.64RR2534 pKa = 11.84DD2535 pKa = 3.24DD2536 pKa = 4.62HH2537 pKa = 8.19IVIDD2541 pKa = 3.64MRR2543 pKa = 11.84YY2544 pKa = 8.34ISEE2547 pKa = 3.95KK2548 pKa = 7.8TTVFFCATQRR2558 pKa = 11.84DD2559 pKa = 4.68CEE2561 pKa = 4.44SGASFAQANGITGYY2575 pKa = 10.77AYY2577 pKa = 10.38HH2578 pKa = 7.82ADD2580 pKa = 3.38TKK2582 pKa = 10.73QAVFNSILSEE2592 pKa = 4.42EE2593 pKa = 4.58GTCWVFATNVIQQSVTIPNLVAVVDD2618 pKa = 4.41LGKK2621 pKa = 10.31EE2622 pKa = 3.78CRR2624 pKa = 11.84PQVRR2628 pKa = 11.84ISDD2631 pKa = 4.0CPLQFVCRR2639 pKa = 11.84LQARR2643 pKa = 11.84DD2644 pKa = 3.18TDD2646 pKa = 4.23LNTFVQRR2653 pKa = 11.84KK2654 pKa = 8.13GRR2656 pKa = 11.84VGRR2659 pKa = 11.84TRR2661 pKa = 11.84PGFCISSPNKK2671 pKa = 8.57SHH2673 pKa = 6.91SNRR2676 pKa = 11.84SVEE2679 pKa = 4.83DD2680 pKa = 3.56FVLPYY2685 pKa = 10.62VVLKK2689 pKa = 10.77LLEE2692 pKa = 3.98HH2693 pKa = 6.27HH2694 pKa = 7.1RR2695 pKa = 11.84SLEE2698 pKa = 3.73EE2699 pKa = 3.93LRR2701 pKa = 11.84CHH2703 pKa = 5.76NAEE2706 pKa = 5.94LIDD2709 pKa = 4.2ALQKK2713 pKa = 10.61LSWMSPEE2720 pKa = 3.73NMRR2723 pKa = 11.84EE2724 pKa = 3.95KK2725 pKa = 10.4IATADD2730 pKa = 3.11QDD2732 pKa = 4.43YY2733 pKa = 11.12VCDD2736 pKa = 4.24SLIEE2740 pKa = 3.96KK2741 pKa = 10.24HH2742 pKa = 6.2NRR2744 pKa = 11.84KK2745 pKa = 9.1QYY2747 pKa = 10.74RR2748 pKa = 11.84GVQFDD2753 pKa = 3.68WKK2755 pKa = 10.68IKK2757 pKa = 10.29DD2758 pKa = 3.91SGNKK2762 pKa = 9.46PYY2764 pKa = 11.08DD2765 pKa = 3.52PVKK2768 pKa = 10.49HH2769 pKa = 6.02YY2770 pKa = 10.29LRR2772 pKa = 11.84CWITDD2777 pKa = 3.47SEE2779 pKa = 4.43VSYY2782 pKa = 9.76WCSNGQGVYY2791 pKa = 9.7MKK2793 pKa = 10.51DD2794 pKa = 3.48LIKK2797 pKa = 9.33THH2799 pKa = 6.25PVIKK2803 pKa = 10.38LSEE2806 pKa = 4.03EE2807 pKa = 4.26QEE2809 pKa = 3.83WSEE2812 pKa = 3.91FSSFKK2817 pKa = 10.58DD2818 pKa = 3.23PHH2820 pKa = 6.53DD2821 pKa = 3.85AALLEE2826 pKa = 4.33KK2827 pKa = 10.09EE2828 pKa = 4.81RR2829 pKa = 11.84KK2830 pKa = 10.04GKK2832 pKa = 10.31DD2833 pKa = 2.98DD2834 pKa = 4.22DD2835 pKa = 5.19LRR2837 pKa = 11.84VGDD2840 pKa = 3.89TKK2842 pKa = 11.08EE2843 pKa = 4.21YY2844 pKa = 10.64DD2845 pKa = 3.48DD2846 pKa = 4.22QAALEE2851 pKa = 5.33DD2852 pKa = 3.71ISEE2855 pKa = 4.2MSLAGPFALGLLGLTGAGVIIYY2877 pKa = 8.9EE2878 pKa = 4.7LIDD2881 pKa = 3.86RR2882 pKa = 11.84KK2883 pKa = 10.0CDD2885 pKa = 3.1RR2886 pKa = 11.84YY2887 pKa = 8.03VTHH2890 pKa = 6.22MVSVAEE2896 pKa = 4.03VDD2898 pKa = 3.9VVSCAKK2904 pKa = 10.36FYY2906 pKa = 11.33AEE2908 pKa = 3.94EE2909 pKa = 4.31SLAKK2913 pKa = 9.43MAPQSEE2919 pKa = 4.63NIISALSVLKK2929 pKa = 10.35MMKK2932 pKa = 10.41NEE2934 pKa = 4.02VKK2936 pKa = 10.47HH2937 pKa = 5.27LLRR2940 pKa = 11.84RR2941 pKa = 11.84KK2942 pKa = 7.13TNKK2945 pKa = 9.95LFEE2948 pKa = 4.64LFPWLKK2954 pKa = 10.77PKK2956 pKa = 10.39DD2957 pKa = 3.83KK2958 pKa = 10.38KK2959 pKa = 10.27IKK2961 pKa = 10.21EE2962 pKa = 4.07MSSVDD2967 pKa = 3.0WMSAIEE2973 pKa = 4.32GMLNTAMAAVSNWTATFGMTMGSVFGSLGGGGLLGFIYY3011 pKa = 10.54KK3012 pKa = 10.37DD3013 pKa = 3.29LEE3015 pKa = 4.46KK3016 pKa = 11.53NMGTVLAMVVGAILHH3031 pKa = 5.48GVVFGAMSIKK3041 pKa = 10.41AYY3043 pKa = 10.41GIFAIGQLVTMLVRR3057 pKa = 11.84CVYY3060 pKa = 10.84GNYY3063 pKa = 7.89TRR3065 pKa = 11.84RR3066 pKa = 11.84SGALYY3071 pKa = 9.96TEE3073 pKa = 4.39NHH3075 pKa = 6.13NSGTFWSAIIAGGIGVGFSQVFKK3098 pKa = 9.51QTAMQAACHH3107 pKa = 5.36NQISTVISQASVTTQAGAVGVPILLVKK3134 pKa = 10.47NLYY3137 pKa = 10.44HH3138 pKa = 7.34LFTRR3142 pKa = 11.84AKK3144 pKa = 10.17NFGEE3148 pKa = 4.27IAGSATMVATLILTSSPLTFLYY3170 pKa = 10.63SGAAALTIFGLRR3182 pKa = 11.84CFAEE3186 pKa = 3.95YY3187 pKa = 9.37MIDD3190 pKa = 3.17QAARR3194 pKa = 11.84KK3195 pKa = 8.88EE3196 pKa = 3.81RR3197 pKa = 11.84DD3198 pKa = 3.34GAGGAQHH3205 pKa = 6.85FEE3207 pKa = 3.96EE3208 pKa = 4.42QKK3210 pKa = 10.44RR3211 pKa = 11.84RR3212 pKa = 11.84LRR3214 pKa = 11.84CAVGAVLDD3222 pKa = 3.94AAAVIVYY3229 pKa = 8.35PSSLISVVIGIISEE3243 pKa = 4.13MAMGSTWRR3251 pKa = 11.84DD3252 pKa = 3.02SCEE3255 pKa = 4.13QSWDD3259 pKa = 3.47AYY3261 pKa = 10.91SGVSPFIAAISEE3273 pKa = 3.97IWRR3276 pKa = 11.84HH3277 pKa = 4.84VISFNRR3283 pKa = 11.84NPVSRR3288 pKa = 11.84EE3289 pKa = 3.27EE3290 pKa = 3.97AQQMSITAVSEE3301 pKa = 3.83MWTKK3305 pKa = 9.56FTDD3308 pKa = 3.23LCKK3311 pKa = 10.28RR3312 pKa = 11.84YY3313 pKa = 9.55LGHH3316 pKa = 7.0FNGVGKK3322 pKa = 10.68KK3323 pKa = 9.53IVSTLRR3329 pKa = 11.84KK3330 pKa = 7.99VWDD3333 pKa = 3.56WLVEE3337 pKa = 3.97HH3338 pKa = 6.9LKK3340 pKa = 10.94ACIVQPISSVMSGVVGKK3357 pKa = 8.92CVRR3360 pKa = 11.84DD3361 pKa = 3.71NINNNWLTRR3370 pKa = 11.84SVFRR3374 pKa = 11.84MNDD3377 pKa = 2.85EE3378 pKa = 3.84PAEE3381 pKa = 4.19EE3382 pKa = 4.2KK3383 pKa = 10.44KK3384 pKa = 10.65QYY3386 pKa = 10.09PNPNYY3391 pKa = 10.59SEE3393 pKa = 4.21MSAVMLNRR3401 pKa = 11.84YY3402 pKa = 9.47SEE3404 pKa = 4.32GKK3406 pKa = 8.94MLDD3409 pKa = 4.67LDD3411 pKa = 4.38TFWLDD3416 pKa = 3.19SGAGSVKK3423 pKa = 10.25EE3424 pKa = 4.0YY3425 pKa = 11.27GSMFDD3430 pKa = 3.97NMLISEE3436 pKa = 4.44VTLLRR3441 pKa = 11.84PNKK3444 pKa = 9.37GKK3446 pKa = 10.71KK3447 pKa = 9.28IVTTEE3452 pKa = 3.84PLALYY3457 pKa = 7.88QVPMDD3462 pKa = 4.66KK3463 pKa = 10.73LLEE3466 pKa = 4.19LLNLTVANCQIKK3478 pKa = 9.85NNVMEE3483 pKa = 4.49FDD3485 pKa = 3.89VPTGSSACPVVKK3497 pKa = 10.72VSFTNTFSEE3506 pKa = 4.87GSMLACIKK3514 pKa = 10.55HH3515 pKa = 5.8KK3516 pKa = 10.92APVFAGYY3523 pKa = 9.72WLMWFYY3529 pKa = 11.39RR3530 pKa = 11.84NYY3532 pKa = 10.62QGATEE3537 pKa = 4.12INIIEE3542 pKa = 4.39YY3543 pKa = 10.71GDD3545 pKa = 3.41TDD3547 pKa = 5.16GITDD3551 pKa = 3.55QLLATLQAQCSLLAGQPKK3569 pKa = 9.9EE3570 pKa = 3.77LTEE3573 pKa = 4.47RR3574 pKa = 11.84EE3575 pKa = 4.15FLNLHH3580 pKa = 6.06EE3581 pKa = 4.54SLFRR3585 pKa = 11.84VEE3587 pKa = 4.99LPRR3590 pKa = 11.84TSVFSQMLHH3599 pKa = 3.9VTKK3602 pKa = 10.76SKK3604 pKa = 10.23VLNMMTEE3611 pKa = 3.71WPDD3614 pKa = 3.3QLRR3617 pKa = 11.84EE3618 pKa = 3.96RR3619 pKa = 11.84VKK3621 pKa = 10.94VKK3623 pKa = 10.57HH3624 pKa = 6.14PLNFSYY3630 pKa = 10.81LHH3632 pKa = 6.02FLNIKK3637 pKa = 10.33DD3638 pKa = 3.84MSSEE3642 pKa = 4.02EE3643 pKa = 4.0AKK3645 pKa = 10.88QMLDD3649 pKa = 3.22YY3650 pKa = 10.81CRR3652 pKa = 11.84YY3653 pKa = 6.55WQYY3656 pKa = 11.81YY3657 pKa = 8.95IIKK3660 pKa = 9.25CQNLYY3665 pKa = 10.75CRR3667 pKa = 11.84LSNTEE3672 pKa = 3.88YY3673 pKa = 10.96KK3674 pKa = 9.97SPKK3677 pKa = 8.59WNIPQGAQVHH3687 pKa = 5.29WMNVEE3692 pKa = 4.04NPAEE3696 pKa = 4.71PDD3698 pKa = 3.42TAGHH3702 pKa = 6.99ISAQLGCQLIRR3713 pKa = 11.84PGYY3716 pKa = 8.61SSYY3719 pKa = 10.9WDD3721 pKa = 3.61TPLLLTSNKK3730 pKa = 10.14SLTHH3734 pKa = 6.71RR3735 pKa = 11.84LLEE3738 pKa = 4.24LVSVNYY3744 pKa = 9.46EE3745 pKa = 3.51INVRR3749 pKa = 11.84YY3750 pKa = 8.72CHH3752 pKa = 7.01RR3753 pKa = 11.84GANDD3757 pKa = 2.93QWIEE3761 pKa = 3.71EE3762 pKa = 4.23WVICGSTCPKK3772 pKa = 10.45HH3773 pKa = 6.46FISLIYY3779 pKa = 10.82DD3780 pKa = 3.71GDD3782 pKa = 3.75DD3783 pKa = 3.0HH3784 pKa = 7.31FIRR3787 pKa = 11.84MPDD3790 pKa = 3.48CAIIDD3795 pKa = 4.06HH3796 pKa = 5.88CHH3798 pKa = 5.44KK3799 pKa = 9.06TPNVAFISKK3808 pKa = 9.8FAEE3811 pKa = 3.79FDD3813 pKa = 3.0IVMAEE3818 pKa = 4.13FVRR3821 pKa = 11.84DD3822 pKa = 3.24GDD3824 pKa = 4.05RR3825 pKa = 11.84IFTYY3829 pKa = 9.14EE3830 pKa = 4.77HH3831 pKa = 6.6INKK3834 pKa = 9.24IPLARR3839 pKa = 11.84AVSKK3843 pKa = 11.15FEE3845 pKa = 4.34LQVQEE3850 pKa = 3.91QSKK3853 pKa = 10.84KK3854 pKa = 9.28IVQPGTTRR3862 pKa = 11.84TNQVMTLLQDD3872 pKa = 4.01FSRR3875 pKa = 11.84KK3876 pKa = 9.73LGEE3879 pKa = 3.84KK3880 pKa = 10.15SRR3882 pKa = 11.84LVWTQLGDD3890 pKa = 3.27IAKK3893 pKa = 9.69VVAEE3897 pKa = 4.61TRR3899 pKa = 11.84PSDD3902 pKa = 3.27IVEE3905 pKa = 4.25ASTSIITKK3913 pKa = 10.5AIVHH3917 pKa = 6.47KK3918 pKa = 11.13SNDD3921 pKa = 3.39EE3922 pKa = 4.05GEE3924 pKa = 4.34EE3925 pKa = 3.89MSASLFQSFSDD3936 pKa = 3.45LLKK3939 pKa = 10.33IYY3941 pKa = 10.61FSGQDD3946 pKa = 3.2QRR3948 pKa = 11.84VSPNKK3953 pKa = 9.77VDD3955 pKa = 4.34DD3956 pKa = 4.34DD3957 pKa = 4.29ALIEE3961 pKa = 4.14RR3962 pKa = 11.84VNFFLTAAQQKK3973 pKa = 8.85EE3974 pKa = 4.22LLIEE3978 pKa = 4.38RR3979 pKa = 11.84CPTYY3983 pKa = 10.61EE3984 pKa = 4.18SIRR3987 pKa = 11.84ASSEE3991 pKa = 3.51LDD3993 pKa = 3.05TEE3995 pKa = 4.65MEE3997 pKa = 4.29FEE3999 pKa = 4.75DD4000 pKa = 4.38ADD4002 pKa = 4.53SVRR4005 pKa = 11.84LLDD4008 pKa = 3.59NCAVIGFTEE4017 pKa = 4.32ASKK4020 pKa = 11.13GRR4022 pKa = 11.84VPHH4025 pKa = 4.66WTWYY4029 pKa = 9.39KK4030 pKa = 11.09AEE4032 pKa = 4.57DD4033 pKa = 3.28ASKK4036 pKa = 10.33FRR4038 pKa = 11.84RR4039 pKa = 11.84EE4040 pKa = 4.36SITTVAPSDD4049 pKa = 3.69VMALYY4054 pKa = 10.47KK4055 pKa = 10.47KK4056 pKa = 10.92LNDD4059 pKa = 3.28RR4060 pKa = 11.84CISKK4064 pKa = 10.38RR4065 pKa = 11.84QWEE4068 pKa = 4.33KK4069 pKa = 10.68LRR4071 pKa = 11.84YY4072 pKa = 8.12ADD4074 pKa = 4.81RR4075 pKa = 11.84YY4076 pKa = 9.65RR4077 pKa = 11.84LPSSLEE4083 pKa = 3.54QKK4085 pKa = 10.92ANEE4088 pKa = 4.06EE4089 pKa = 4.06VKK4091 pKa = 9.73ACSRR4095 pKa = 11.84AFYY4098 pKa = 10.97KK4099 pKa = 9.54MQQLFEE4105 pKa = 5.17ADD4107 pKa = 3.11PAFFEE4112 pKa = 4.39NCHH4115 pKa = 6.57TILDD4119 pKa = 4.26PACGYY4124 pKa = 11.14GGFSQYY4130 pKa = 11.16LSNKK4134 pKa = 8.49LASGAPKK4141 pKa = 9.93TILAGSLIQKK4151 pKa = 7.2GHH4153 pKa = 7.72RR4154 pKa = 11.84IPDD4157 pKa = 3.49MSRR4160 pKa = 11.84LTAHH4164 pKa = 7.15GSNVRR4169 pKa = 11.84VVNLCRR4175 pKa = 11.84PDD4177 pKa = 4.32LDD4179 pKa = 5.14NGDD4182 pKa = 4.56LRR4184 pKa = 11.84NKK4186 pKa = 9.31MVLNRR4191 pKa = 11.84YY4192 pKa = 7.62LHH4194 pKa = 6.41EE4195 pKa = 4.13SHH4197 pKa = 6.87KK4198 pKa = 10.83FEE4200 pKa = 5.48GMDD4203 pKa = 3.9LVLYY4207 pKa = 11.01DD4208 pKa = 3.52MGEE4211 pKa = 3.98FFDD4214 pKa = 4.67NSKK4217 pKa = 10.91DD4218 pKa = 3.69QYY4220 pKa = 11.34NWWTKK4225 pKa = 7.22PAKK4228 pKa = 10.29DD4229 pKa = 3.32ISEE4232 pKa = 4.58DD4233 pKa = 3.62NQVSLIEE4240 pKa = 4.57GMATLLKK4247 pKa = 9.46TLRR4250 pKa = 11.84AGGRR4254 pKa = 11.84MLLKK4258 pKa = 7.52WTGYY4262 pKa = 9.52FGCGDD4267 pKa = 3.85EE4268 pKa = 5.35LLQKK4272 pKa = 10.83LLSCFKK4278 pKa = 10.15NFKK4281 pKa = 9.69AIKK4284 pKa = 9.56VGTSSLYY4291 pKa = 7.59TTEE4294 pKa = 4.38FYY4296 pKa = 10.24IYY4298 pKa = 10.52ASGYY4302 pKa = 8.53TGLTSTSVGRR4312 pKa = 11.84VRR4314 pKa = 11.84RR4315 pKa = 11.84FYY4317 pKa = 11.33EE4318 pKa = 4.3EE4319 pKa = 3.65IGEE4322 pKa = 4.47CIYY4325 pKa = 11.08SQLIRR4330 pKa = 11.84ANHH4333 pKa = 5.41IMMHH4337 pKa = 6.29PSYY4340 pKa = 9.6YY4341 pKa = 9.91PPMEE4345 pKa = 5.1RR4346 pKa = 11.84GDD4348 pKa = 3.6WEE4350 pKa = 4.56YY4351 pKa = 10.3PASTGVVYY4359 pKa = 10.5RR4360 pKa = 11.84ADD4362 pKa = 3.48ANEE4365 pKa = 3.75NRR4367 pKa = 11.84PGGIEE4372 pKa = 3.99WEE4374 pKa = 3.82LHH4376 pKa = 5.13YY4377 pKa = 10.8AGKK4380 pKa = 9.93VLKK4383 pKa = 10.04EE4384 pKa = 3.57SWMPNWDD4391 pKa = 3.3EE4392 pKa = 3.78RR4393 pKa = 11.84HH4394 pKa = 6.23QIFQQVVRR4402 pKa = 11.84RR4403 pKa = 11.84EE4404 pKa = 4.31LYY4406 pKa = 10.24RR4407 pKa = 11.84EE4408 pKa = 3.87TPTRR4412 pKa = 11.84RR4413 pKa = 11.84LRR4415 pKa = 11.84YY4416 pKa = 9.43NRR4418 pKa = 11.84GSNGTYY4424 pKa = 10.33SKK4426 pKa = 10.62LYY4428 pKa = 8.27QDD4430 pKa = 4.13GWFSRR4435 pKa = 11.84PVKK4438 pKa = 10.25NVHH4441 pKa = 6.02EE4442 pKa = 4.31KK4443 pKa = 10.5HH4444 pKa = 6.77SKK4446 pKa = 10.34NDD4448 pKa = 3.8LLNSLCYY4455 pKa = 9.76FVTKK4459 pKa = 8.62TTDD4462 pKa = 3.31DD4463 pKa = 3.86NSTMGQCQATKK4474 pKa = 9.77EE4475 pKa = 3.85YY4476 pKa = 10.83RR4477 pKa = 11.84EE4478 pKa = 3.98ASIKK4482 pKa = 10.48KK4483 pKa = 10.04RR4484 pKa = 11.84IDD4486 pKa = 3.12FEE4488 pKa = 5.25APVLPGYY4495 pKa = 9.93VLEE4498 pKa = 4.54EE4499 pKa = 3.77LAEE4502 pKa = 4.27ILDD4505 pKa = 4.51LMTTEE4510 pKa = 4.02YY4511 pKa = 11.2GKK4513 pKa = 9.12TIEE4516 pKa = 4.47GKK4518 pKa = 10.27CRR4520 pKa = 11.84LLTKK4524 pKa = 10.41EE4525 pKa = 4.12EE4526 pKa = 4.69VYY4528 pKa = 11.69VMLNKK4533 pKa = 10.47NGATSILSKK4542 pKa = 10.62DD4543 pKa = 3.45ANLRR4547 pKa = 11.84NYY4549 pKa = 10.03MEE4551 pKa = 4.45THH4553 pKa = 6.21PNWYY4557 pKa = 8.46EE4558 pKa = 3.76LSMHH4562 pKa = 5.92YY4563 pKa = 10.27CVNRR4567 pKa = 11.84WRR4569 pKa = 11.84KK4570 pKa = 7.81NQPTHH4575 pKa = 5.7GFFNIMHH4582 pKa = 6.55KK4583 pKa = 10.93NEE4585 pKa = 4.03AKK4587 pKa = 10.28AKK4589 pKa = 10.33KK4590 pKa = 9.88NVEE4593 pKa = 3.84QGNICLEE4600 pKa = 4.29RR4601 pKa = 11.84GSDD4604 pKa = 3.31MKK4606 pKa = 11.32YY4607 pKa = 10.42EE4608 pKa = 4.23PDD4610 pKa = 3.41EE4611 pKa = 4.11LRR4613 pKa = 11.84EE4614 pKa = 3.93EE4615 pKa = 4.15LKK4617 pKa = 10.19TYY4619 pKa = 11.25NNLPHH4624 pKa = 7.26RR4625 pKa = 11.84FIQYY4629 pKa = 9.63ADD4631 pKa = 3.93EE4632 pKa = 4.14ITRR4635 pKa = 11.84IAHH4638 pKa = 5.69YY4639 pKa = 10.14IILGDD4644 pKa = 4.49LIEE4647 pKa = 4.92KK4648 pKa = 10.73NSIQKK4653 pKa = 9.82IYY4655 pKa = 10.34KK4656 pKa = 8.48GTVNGCPPAYY4666 pKa = 10.11LGNVLRR4672 pKa = 11.84AAWDD4676 pKa = 3.77LNEE4679 pKa = 5.08PNDD4682 pKa = 3.54KK4683 pKa = 10.84HH4684 pKa = 7.7KK4685 pKa = 11.27VFTATHH4691 pKa = 5.91VDD4693 pKa = 3.38GKK4695 pKa = 9.95HH4696 pKa = 5.39VKK4698 pKa = 8.9EE4699 pKa = 3.77QAGANINVYY4708 pKa = 9.47TSSQLPEE4715 pKa = 3.93GVAPHH4720 pKa = 7.09EE4721 pKa = 4.46DD4722 pKa = 3.86DD4723 pKa = 4.42KK4724 pKa = 11.85PCGLSIDD4731 pKa = 3.8YY4732 pKa = 10.64SSWDD4736 pKa = 3.26GSVSVGEE4743 pKa = 4.85RR4744 pKa = 11.84MLEE4747 pKa = 4.0ANKK4750 pKa = 10.03LASFYY4755 pKa = 10.13PPGMRR4760 pKa = 11.84STIMNACRR4768 pKa = 11.84EE4769 pKa = 4.1MAFAICLDD4777 pKa = 3.43HH4778 pKa = 7.7DD4779 pKa = 4.63GNVCYY4784 pKa = 10.36RR4785 pKa = 11.84SGHH4788 pKa = 5.91RR4789 pKa = 11.84GSGEE4793 pKa = 3.64ILTSIGNTQLVAANTIRR4810 pKa = 11.84AICKK4814 pKa = 9.99VLGLTFKK4821 pKa = 10.68EE4822 pKa = 3.97ALQNRR4827 pKa = 11.84AVITAKK4833 pKa = 10.37VGQKK4837 pKa = 8.59TKK4839 pKa = 9.72IYY4841 pKa = 8.98EE4842 pKa = 4.07VTRR4845 pKa = 11.84IPQFSDD4851 pKa = 3.19GDD4853 pKa = 3.81DD4854 pKa = 3.6TVILTTRR4861 pKa = 11.84RR4862 pKa = 11.84IAKK4865 pKa = 9.58LIEE4868 pKa = 3.87MNIDD4872 pKa = 3.27EE4873 pKa = 4.86EE4874 pKa = 4.44LAIAGKK4880 pKa = 10.22KK4881 pKa = 8.76IRR4883 pKa = 11.84SGTKK4887 pKa = 9.58SGCSKK4892 pKa = 10.54HH4893 pKa = 6.78DD4894 pKa = 3.26QFKK4897 pKa = 9.07TLEE4900 pKa = 4.49FCSHH4904 pKa = 6.3TYY4906 pKa = 10.73EE4907 pKa = 4.96SILVGKK4913 pKa = 8.19QAQYY4917 pKa = 10.12VSCMPHH4923 pKa = 4.29QHH4925 pKa = 7.13RR4926 pKa = 11.84SLCEE4930 pKa = 3.63NFPEE4934 pKa = 4.24FRR4936 pKa = 11.84IRR4938 pKa = 11.84HH4939 pKa = 5.55LPTRR4943 pKa = 11.84PTTDD4947 pKa = 2.58IIGKK4951 pKa = 9.04LRR4953 pKa = 11.84ATLKK4957 pKa = 10.65QSAFKK4962 pKa = 10.67YY4963 pKa = 9.69KK4964 pKa = 10.62HH4965 pKa = 6.55EE4966 pKa = 5.47DD4967 pKa = 3.5DD4968 pKa = 4.68SPTGSKK4974 pKa = 9.97ILTRR4978 pKa = 11.84SKK4980 pKa = 10.72LLSYY4984 pKa = 10.88LLLYY4988 pKa = 7.22PHH4990 pKa = 6.84CRR4992 pKa = 11.84YY4993 pKa = 9.58VRR4995 pKa = 11.84YY4996 pKa = 9.84LCLSGLIVTGDD5007 pKa = 3.27GTVNFDD5013 pKa = 3.23EE5014 pKa = 4.97MIRR5017 pKa = 11.84RR5018 pKa = 11.84YY5019 pKa = 9.5PDD5021 pKa = 2.92YY5022 pKa = 10.97RR5023 pKa = 11.84FVLGKK5028 pKa = 6.47TTLMGALDD5036 pKa = 3.9SVYY5039 pKa = 10.87GVATFDD5045 pKa = 4.59DD5046 pKa = 3.93VGLRR5050 pKa = 11.84QYY5052 pKa = 11.73NDD5054 pKa = 3.45DD5055 pKa = 4.16KK5056 pKa = 11.53RR5057 pKa = 11.84DD5058 pKa = 3.33GRR5060 pKa = 11.84QLRR5063 pKa = 11.84RR5064 pKa = 11.84HH5065 pKa = 5.96AKK5067 pKa = 10.44LIGEE5071 pKa = 4.28VLDD5074 pKa = 4.27IRR5076 pKa = 11.84LQSIVSKK5083 pKa = 11.16AMVWTTNYY5091 pKa = 10.28KK5092 pKa = 9.96FRR5094 pKa = 11.84DD5095 pKa = 3.58WTVAAHH5101 pKa = 7.01DD5102 pKa = 4.17SKK5104 pKa = 10.52FCKK5107 pKa = 9.95MIWKK5111 pKa = 10.06SIITRR5116 pKa = 11.84QVRR5119 pKa = 11.84LFPSEE5124 pKa = 3.29IRR5126 pKa = 11.84QIKK5129 pKa = 10.26SNLDD5133 pKa = 3.24LTKK5136 pKa = 9.83TQIEE5140 pKa = 4.3IPDD5143 pKa = 3.51EE5144 pKa = 4.41SVYY5147 pKa = 10.07STSEE5151 pKa = 3.59EE5152 pKa = 3.86AGILTNYY5159 pKa = 10.21QSDD5162 pKa = 3.63NKK5164 pKa = 11.17SNLNWLSKK5172 pKa = 10.95LFLL5175 pKa = 4.8

Molecular weight: 582.76 kDa
Isoelectric point according different methods:

Protein with the highest isoelectric point:

>tr|A0A0N7JQI5|A0A0N7JQI5_9VIRU Non-structural protein 3 OS=Shayang fly virus 4 OX=1746061 PE=4 SV=1

MM1 pKa = 7.78SITPNASGVARR12 pKa = 11.84NANKK16 pKa = 10.11LAEE19 pKa = 4.03ARR21 pKa = 11.84ILTAAVSGQTKK32 pKa = 10.45RR33 pKa = 11.84LTDD36 pKa = 3.55EE37 pKa = 4.53AKK39 pKa = 10.87ALADD43 pKa = 4.92LANQANNAMMAVVTNMGPTVNSGIRR68 pKa = 11.84KK69 pKa = 8.87KK70 pKa = 10.78RR71 pKa = 11.84KK72 pKa = 6.82TKK74 pKa = 10.3NGKK77 pKa = 8.62GANASNGGIISGVSKK92 pKa = 9.55TIKK95 pKa = 10.44DD96 pKa = 3.3ATNNIFIITSLTLILIIAYY115 pKa = 7.96STASPLNQNTDD126 pKa = 3.29STSSNRR132 pKa = 11.84LGLQFFGKK140 pKa = 10.07DD141 pKa = 3.35FQEE144 pKa = 4.94IEE146 pKa = 4.03GKK148 pKa = 9.35IAKK151 pKa = 8.8TGLKK155 pKa = 9.87CKK157 pKa = 9.53SARR160 pKa = 11.84DD161 pKa = 3.86CTNVVVDD168 pKa = 6.32LMNADD173 pKa = 3.84QKK175 pKa = 11.55DD176 pKa = 3.84KK177 pKa = 10.5PDD179 pKa = 3.81CNILVNHH186 pKa = 6.63ATNLASIAPGKK197 pKa = 10.28SVLRR201 pKa = 11.84AKK203 pKa = 10.61LVDD206 pKa = 4.05YY207 pKa = 11.35YY208 pKa = 10.55MEE210 pKa = 5.38PLLKK214 pKa = 10.57CKK216 pKa = 10.0TDD218 pKa = 2.9IKK220 pKa = 11.12NIFLRR225 pKa = 11.84YY226 pKa = 9.4DD227 pKa = 3.76AIEE230 pKa = 4.15YY231 pKa = 10.72KK232 pKa = 10.29EE233 pKa = 4.73DD234 pKa = 3.46PVKK237 pKa = 10.74FMCYY241 pKa = 10.37LLDD244 pKa = 4.67CDD246 pKa = 3.85QKK248 pKa = 11.61SRR250 pKa = 11.84ADD252 pKa = 3.51LQVEE256 pKa = 4.39FEE258 pKa = 4.3TLKK261 pKa = 9.55TQDD264 pKa = 3.36TNTLRR269 pKa = 11.84EE270 pKa = 4.01IEE272 pKa = 4.44KK273 pKa = 10.88LLNTYY278 pKa = 11.19NDD280 pKa = 3.37MVLDD284 pKa = 3.86KK285 pKa = 10.3MVNLQISSEE294 pKa = 4.04ITDD297 pKa = 4.11KK298 pKa = 11.02FQKK301 pKa = 8.56TCKK304 pKa = 10.58DD305 pKa = 3.2NMNALNNRR313 pKa = 11.84YY314 pKa = 9.27GGRR317 pKa = 11.84YY318 pKa = 9.33GKK320 pKa = 10.1ISNLLEE326 pKa = 4.78KK327 pKa = 10.25IEE329 pKa = 4.65KK330 pKa = 8.17STKK333 pKa = 10.2NLITEE338 pKa = 4.26IEE340 pKa = 4.47SNNKK344 pKa = 9.75KK345 pKa = 10.27LDD347 pKa = 3.64NLAEE351 pKa = 4.31QIEE354 pKa = 4.35DD355 pKa = 3.17MPRR358 pKa = 11.84RR359 pKa = 11.84IKK361 pKa = 10.89RR362 pKa = 11.84EE363 pKa = 3.58TSQDD367 pKa = 2.11KK368 pKa = 9.18WANFKK373 pKa = 10.85SDD375 pKa = 2.98SQTIMTCLSKK385 pKa = 11.25LNIVCSSQATCRR397 pKa = 11.84TSINEE402 pKa = 4.12VVDD405 pKa = 3.72GLKK408 pKa = 10.84DD409 pKa = 3.46KK410 pKa = 11.13SVEE413 pKa = 4.1DD414 pKa = 3.65NQFEE418 pKa = 5.15LNFGTIKK425 pKa = 10.69DD426 pKa = 3.76LRR428 pKa = 11.84EE429 pKa = 4.3CIVTGSAVHH438 pKa = 5.89EE439 pKa = 4.71AIEE442 pKa = 4.11PKK444 pKa = 9.91INEE447 pKa = 4.06YY448 pKa = 9.81IARR451 pKa = 11.84HH452 pKa = 5.01GRR454 pKa = 11.84YY455 pKa = 8.81VSCKK459 pKa = 8.37AQVDD463 pKa = 4.25VVQANLKK470 pKa = 9.97YY471 pKa = 7.47MTGVIVDD478 pKa = 4.05DD479 pKa = 4.21VEE481 pKa = 4.45VMSEE485 pKa = 3.94KK486 pKa = 10.41RR487 pKa = 11.84CPLFLDD493 pKa = 3.7VLNEE497 pKa = 3.83KK498 pKa = 10.2YY499 pKa = 10.38IQIKK503 pKa = 10.35RR504 pKa = 11.84FGHH507 pKa = 4.51EE508 pKa = 3.9TGTKK512 pKa = 8.62IDD514 pKa = 3.9EE515 pKa = 4.32KK516 pKa = 11.18AVLIKK521 pKa = 10.54PCEE524 pKa = 4.0EE525 pKa = 3.97NKK527 pKa = 10.01NWQHH531 pKa = 6.92DD532 pKa = 3.41GWLGGNSGSCATGIDD547 pKa = 3.52KK548 pKa = 10.31TSWDD552 pKa = 3.37VRR554 pKa = 11.84EE555 pKa = 5.12CIKK558 pKa = 10.68QPYY561 pKa = 6.27GTCMHH566 pKa = 6.88KK567 pKa = 10.71KK568 pKa = 10.31SDD570 pKa = 3.96TCVLGYY576 pKa = 11.17GNVVVKK582 pKa = 10.63KK583 pKa = 10.51PNTLYY588 pKa = 10.67TNSYY592 pKa = 9.82KK593 pKa = 10.62NASNPICCTMSCFEE607 pKa = 5.5LSDD610 pKa = 4.32LYY612 pKa = 10.93LTFTNQPLCAPCIKK626 pKa = 10.54AFSTVFWGDD635 pKa = 2.8VCLKK639 pKa = 9.94HH640 pKa = 7.47VSGEE644 pKa = 3.65ISGINIYY651 pKa = 10.54SSQTVFDD658 pKa = 5.14LPDD661 pKa = 3.73HH662 pKa = 6.97SKK664 pKa = 8.79VTCPNAYY671 pKa = 9.99RR672 pKa = 11.84FNQCCAGKK680 pKa = 10.55GPAPVGSQSVFKK692 pKa = 10.74DD693 pKa = 3.77KK694 pKa = 11.61YY695 pKa = 9.21CVCSLKK701 pKa = 10.81HH702 pKa = 5.54PSWYY706 pKa = 10.5DD707 pKa = 3.26MILAKK712 pKa = 10.45INTLKK717 pKa = 11.11KK718 pKa = 9.97NVFKK722 pKa = 10.81VDD724 pKa = 3.37HH725 pKa = 6.93LIAFAILFLIFCWHH739 pKa = 6.86HH740 pKa = 5.74GLGTVLVVAYY750 pKa = 8.65LSWIVISVEE759 pKa = 4.39GACHH763 pKa = 5.84VEE765 pKa = 3.79NMVPRR770 pKa = 11.84SAIVGLSNGLPIEE783 pKa = 4.2HH784 pKa = 6.29MRR786 pKa = 11.84VRR788 pKa = 11.84PGQCFVAGDD797 pKa = 3.66ATVEE801 pKa = 3.93IVAIRR806 pKa = 11.84VFHH809 pKa = 7.04IYY811 pKa = 10.77NFLRR815 pKa = 11.84AIPYY819 pKa = 9.35KK820 pKa = 10.19IKK822 pKa = 10.27PVCQVFDD829 pKa = 3.89WGCKK833 pKa = 9.89GGMSDD838 pKa = 3.62AVYY841 pKa = 10.47NIKK844 pKa = 10.28SDD846 pKa = 3.81CYY848 pKa = 9.06NNCVPGLRR856 pKa = 11.84KK857 pKa = 9.59QIKK860 pKa = 8.91GAEE863 pKa = 4.21AEE865 pKa = 4.28WSGDD869 pKa = 2.67ACFFMGRR876 pKa = 11.84VATRR880 pKa = 11.84LDD882 pKa = 3.19VCFSYY887 pKa = 10.84GATSTFVDD895 pKa = 5.18LYY897 pKa = 11.32SRR899 pKa = 11.84ISGDD903 pKa = 3.13PHH905 pKa = 8.27IEE907 pKa = 3.93LTVKK911 pKa = 9.84FHH913 pKa = 7.22GIGFEE918 pKa = 4.43GVGHH922 pKa = 7.26ISTSSLDD929 pKa = 3.57GPEE932 pKa = 4.31KK933 pKa = 10.42IKK935 pKa = 10.47IYY937 pKa = 10.19NIRR940 pKa = 11.84AAAQLWPEE948 pKa = 4.27MISYY952 pKa = 10.52RR953 pKa = 11.84LSKK956 pKa = 9.94YY957 pKa = 9.62LCAYY961 pKa = 10.15HH962 pKa = 6.39YY963 pKa = 11.0VEE965 pKa = 5.79SANTCNSGDD974 pKa = 3.53VFKK977 pKa = 11.12PNDD980 pKa = 3.54IDD982 pKa = 4.84ADD984 pKa = 4.12CLNLQQRR991 pKa = 11.84WNIEE995 pKa = 3.64HH996 pKa = 6.98GGYY999 pKa = 9.66QVTYY1003 pKa = 8.5DD1004 pKa = 3.63TKK1006 pKa = 11.15DD1007 pKa = 3.28FEE1009 pKa = 4.58QQLHH1013 pKa = 6.21SSFVDD1018 pKa = 3.57CSLNSFINNTATTLKK1033 pKa = 10.62YY1034 pKa = 11.05YY1035 pKa = 10.36EE1036 pKa = 4.29DD1037 pKa = 3.87QVWAEE1042 pKa = 4.26FDD1044 pKa = 3.11ISSTKK1049 pKa = 9.26FTFASSVPLCLDD1061 pKa = 3.69LNSWNISAEE1070 pKa = 3.91AGITGYY1076 pKa = 10.69HH1077 pKa = 6.12RR1078 pKa = 11.84VTKK1081 pKa = 10.35IKK1083 pKa = 10.36FINAGSRR1090 pKa = 11.84CRR1092 pKa = 11.84LFFDD1096 pKa = 4.59MDD1098 pKa = 4.04DD1099 pKa = 4.04CLSTNGRR1106 pKa = 11.84LIVLGKK1112 pKa = 10.4NEE1114 pKa = 4.1GPHH1117 pKa = 6.36TIEE1120 pKa = 4.2YY1121 pKa = 8.87WCGDD1125 pKa = 3.32NSTGRR1130 pKa = 11.84AEE1132 pKa = 3.64IHH1134 pKa = 5.97LAEE1137 pKa = 5.37DD1138 pKa = 3.3KK1139 pKa = 11.68AEE1141 pKa = 3.66IRR1143 pKa = 11.84TFNILTNFVPHH1154 pKa = 7.08KK1155 pKa = 9.08NTIRR1159 pKa = 11.84NTFTRR1164 pKa = 11.84VINGGSVADD1173 pKa = 4.49LSAILSNAFDD1183 pKa = 4.29SLNLASWYY1191 pKa = 10.23HH1192 pKa = 7.0AITKK1196 pKa = 9.15FFGGFFKK1203 pKa = 10.91FGLFKK1208 pKa = 10.87LALGALLALGAWNCFVRR1225 pKa = 11.84GNMVGVFLCCLLFWLLILTDD1245 pKa = 4.79LVIATNQSHH1254 pKa = 6.95AAPIRR1259 pKa = 11.84IVSTITDD1266 pKa = 3.66MVVGLVFAVVVFVLKK1281 pKa = 10.75CPMRR1285 pKa = 11.84AALTTSFVLRR1295 pKa = 11.84TFYY1298 pKa = 10.73CSCLWFVNVVFHH1310 pKa = 4.54MHH1312 pKa = 5.71IVKK1315 pKa = 10.4FEE1317 pKa = 4.18LCLNILSEE1325 pKa = 4.35TLAVILSVWSEE1336 pKa = 3.72DD1337 pKa = 3.98RR1338 pKa = 11.84IVMLCAFSWLCYY1350 pKa = 9.84IHH1352 pKa = 7.04GKK1354 pKa = 9.38HH1355 pKa = 6.24LMCNSPVVNKK1365 pKa = 9.12GTMYY1369 pKa = 10.63LHH1371 pKa = 7.4PLTALITLKK1380 pKa = 10.78DD1381 pKa = 3.45HH1382 pKa = 5.99SEE1384 pKa = 3.56RR1385 pKa = 11.84RR1386 pKa = 11.84AIVNEE1391 pKa = 3.69ANNAHH1396 pKa = 5.96NTLDD1400 pKa = 4.1SIIDD1404 pKa = 3.79QNHH1407 pKa = 5.8HH1408 pKa = 5.79RR1409 pKa = 11.84VAGISNAFFCAPNKK1423 pKa = 10.28VKK1425 pKa = 9.88TDD1427 pKa = 3.82KK1428 pKa = 10.86IVVEE1432 pKa = 4.27IEE1434 pKa = 4.12DD1435 pKa = 4.16PLVSGGLTTIRR1446 pKa = 11.84TSKK1449 pKa = 10.72YY1450 pKa = 7.21GTVYY1454 pKa = 10.67VADD1457 pKa = 4.06INKK1460 pKa = 9.19KK1461 pKa = 9.83LCFAVMRR1468 pKa = 11.84HH1469 pKa = 4.82SVEE1472 pKa = 4.21PEE1474 pKa = 3.05ITMEE1478 pKa = 5.68DD1479 pKa = 3.9DD1480 pKa = 3.2VCYY1483 pKa = 8.64ATPAILSLIEE1493 pKa = 4.1KK1494 pKa = 8.51TAVPYY1499 pKa = 10.68SVLRR1503 pKa = 11.84CHH1505 pKa = 6.88IGEE1508 pKa = 4.48SGTAVVKK1515 pKa = 10.61DD1516 pKa = 3.75GKK1518 pKa = 10.64LQFLSGVRR1526 pKa = 11.84NGNPFFVGSVEE1537 pKa = 4.13PPKK1540 pKa = 10.77SLEE1543 pKa = 3.62IVTKK1547 pKa = 10.23VKK1549 pKa = 10.65EE1550 pKa = 4.43STSEE1554 pKa = 3.81ADD1556 pKa = 3.32PNIIKK1561 pKa = 10.73VKK1563 pKa = 10.44DD1564 pKa = 3.81PYY1566 pKa = 9.33GTEE1569 pKa = 3.78YY1570 pKa = 10.67QYY1572 pKa = 11.91SHH1574 pKa = 6.92GSLISKK1580 pKa = 9.01KK1581 pKa = 9.06IWAKK1585 pKa = 9.87HH1586 pKa = 5.0SSSKK1590 pKa = 10.65GVPLCADD1597 pKa = 3.29VQVADD1602 pKa = 4.7EE1603 pKa = 4.33STAIYY1608 pKa = 9.92SGCEE1612 pKa = 3.49KK1613 pKa = 10.57LDD1615 pKa = 3.45RR1616 pKa = 11.84KK1617 pKa = 10.4IFGVPVHH1624 pKa = 6.01SAYY1627 pKa = 9.88TFIFNKK1633 pKa = 9.07ATATCDD1639 pKa = 4.11AISCPIIGDD1648 pKa = 4.31RR1649 pKa = 11.84IWISKK1654 pKa = 9.4NIKK1657 pKa = 10.08EE1658 pKa = 4.21GLQDD1662 pKa = 3.32VAHH1665 pKa = 5.54VQKK1668 pKa = 10.89SYY1670 pKa = 11.53VFTTDD1675 pKa = 2.79KK1676 pKa = 11.16VLTSGSGIYY1685 pKa = 10.07IKK1687 pKa = 10.41VSCSRR1692 pKa = 11.84YY1693 pKa = 9.61IMISVVTKK1701 pKa = 8.84SFRR1704 pKa = 11.84MEE1706 pKa = 4.15GSDD1709 pKa = 4.34LIHH1712 pKa = 6.83YY1713 pKa = 7.46YY1714 pKa = 9.99ISRR1717 pKa = 11.84PNDD1720 pKa = 3.06CRR1722 pKa = 11.84ILTTIKK1728 pKa = 10.58NVEE1731 pKa = 3.84IEE1733 pKa = 3.98QKK1735 pKa = 10.17IRR1737 pKa = 11.84NDD1739 pKa = 3.74CADD1742 pKa = 3.68EE1743 pKa = 4.13TSPTTIVAFSHH1754 pKa = 4.82YY1755 pKa = 9.89QRR1757 pKa = 11.84GRR1759 pKa = 11.84FHH1761 pKa = 5.86ITEE1764 pKa = 5.21FIDD1767 pKa = 3.7TKK1769 pKa = 9.4EE1770 pKa = 3.98KK1771 pKa = 10.93CVMRR1775 pKa = 11.84LQATLAGVGFINKK1788 pKa = 8.69SHH1790 pKa = 6.89SDD1792 pKa = 3.42SGSDD1796 pKa = 3.37TDD1798 pKa = 4.83CGIVGQSPRR1807 pKa = 11.84KK1808 pKa = 9.54RR1809 pKa = 11.84FYY1811 pKa = 11.73DD1812 pKa = 3.45MDD1814 pKa = 3.52QSRR1817 pKa = 11.84MKK1819 pKa = 10.71KK1820 pKa = 9.28FFNRR1824 pKa = 11.84KK1825 pKa = 8.44GFTWPDD1831 pKa = 3.0RR1832 pKa = 11.84FLVDD1836 pKa = 3.26SAIRR1840 pKa = 11.84SIFQDD1845 pKa = 3.58LAKK1848 pKa = 10.45SIPEE1852 pKa = 3.94QEE1854 pKa = 4.23VMLSVGLLKK1863 pKa = 10.57EE1864 pKa = 4.1MKK1866 pKa = 9.5DD1867 pKa = 3.15RR1868 pKa = 11.84RR1869 pKa = 11.84MFSHH1873 pKa = 6.5YY1874 pKa = 9.8NWAYY1878 pKa = 10.79VSWQMLQVRR1887 pKa = 11.84NKK1889 pKa = 10.24NLEE1892 pKa = 4.33LNPDD1896 pKa = 3.64APWWKK1901 pKa = 9.88NYY1903 pKa = 10.09KK1904 pKa = 10.38GIIADD1909 pKa = 3.84TPIDD1913 pKa = 3.54HH1914 pKa = 6.71TAVDD1918 pKa = 4.29FGGDD1922 pKa = 3.47RR1923 pKa = 11.84DD1924 pKa = 3.98LVTPLMHH1931 pKa = 5.88VAAYY1935 pKa = 9.75GKK1937 pKa = 10.25AQIGYY1942 pKa = 8.16QGKK1945 pKa = 8.24VHH1947 pKa = 7.05LIVHH1951 pKa = 7.04PDD1953 pKa = 3.19PSFAKK1958 pKa = 8.75ITEE1961 pKa = 4.0ISEE1964 pKa = 4.15DD1965 pKa = 3.69NHH1967 pKa = 5.07WQIIDD1972 pKa = 3.59VPDD1975 pKa = 5.32RR1976 pKa = 11.84IPRR1979 pKa = 11.84MAKK1982 pKa = 9.8RR1983 pKa = 11.84YY1984 pKa = 8.2LHH1986 pKa = 6.06EE1987 pKa = 4.33AVSRR1991 pKa = 11.84GLRR1994 pKa = 11.84SIKK1997 pKa = 10.2ILISKK2002 pKa = 8.16PYY2004 pKa = 7.81WQEE2007 pKa = 3.74LGNEE2011 pKa = 4.14YY2012 pKa = 10.26QGEE2015 pKa = 4.06FDD2017 pKa = 4.36IPAALSLCCALWVEE2031 pKa = 4.38TEE2033 pKa = 4.14YY2034 pKa = 11.74VDD2036 pKa = 5.21DD2037 pKa = 4.35FKK2039 pKa = 11.14TYY2041 pKa = 10.47VSNGRR2046 pKa = 11.84NLSRR2050 pKa = 11.84GFLPSLKK2057 pKa = 10.53AGLTQPWHH2065 pKa = 6.03TPDD2068 pKa = 3.45EE2069 pKa = 4.16KK2070 pKa = 11.29LKK2072 pKa = 9.55VSEE2075 pKa = 4.5YY2076 pKa = 11.05GEE2078 pKa = 4.0QLLTYY2083 pKa = 10.4SNFWKK2088 pKa = 9.25RR2089 pKa = 11.84TIASGCAEE2097 pKa = 4.13PHH2099 pKa = 6.55DD2100 pKa = 4.19VLLTRR2105 pKa = 11.84TTNCNNISEE2114 pKa = 4.43ARR2116 pKa = 11.84LANKK2120 pKa = 9.75RR2121 pKa = 11.84LHH2123 pKa = 6.05ICSLRR2128 pKa = 11.84NFTSRR2133 pKa = 11.84GSCFIYY2139 pKa = 10.49DD2140 pKa = 4.01GSVVTSWHH2148 pKa = 5.33CTKK2151 pKa = 10.86GNAIRR2156 pKa = 11.84VTNCDD2161 pKa = 2.35KK2162 pKa = 11.04TMRR2165 pKa = 11.84FDD2167 pKa = 3.88APVMQSKK2174 pKa = 10.09AQDD2177 pKa = 2.89IAVYY2181 pKa = 9.98GKK2183 pKa = 10.42KK2184 pKa = 8.93LTFAKK2189 pKa = 9.75MSLGEE2194 pKa = 4.03IVVTFNPITHH2204 pKa = 6.84FGMYY2208 pKa = 9.81FVVEE2212 pKa = 4.31SLNATLEE2219 pKa = 4.19GRR2221 pKa = 11.84PGAQFAKK2228 pKa = 10.04LLPVRR2233 pKa = 11.84IDD2235 pKa = 3.22NEE2237 pKa = 4.26ANVIRR2242 pKa = 11.84VPYY2245 pKa = 10.19HH2246 pKa = 6.16HH2247 pKa = 7.33GCSGSPIVNYY2257 pKa = 10.26QGDD2260 pKa = 3.67IVGVFGLGTDD2270 pKa = 3.59VAYY2273 pKa = 7.55TTATGKK2279 pKa = 10.25ISTVAHH2285 pKa = 6.52FSPIGGLQLDD2295 pKa = 3.6SMAFFEE2301 pKa = 4.49ACARR2305 pKa = 11.84NFLEE2309 pKa = 4.57APKK2312 pKa = 10.46SGEE2315 pKa = 3.72FTACYY2320 pKa = 10.25LNAPTGSGKK2329 pKa = 6.96TTQFPLALAEE2339 pKa = 4.01EE2340 pKa = 4.91LIKK2343 pKa = 10.75RR2344 pKa = 11.84EE2345 pKa = 3.84TGMGCTHH2352 pKa = 7.65ILICQPNVDD2361 pKa = 3.83AVKK2364 pKa = 10.86NGAKK2368 pKa = 9.93RR2369 pKa = 11.84AATAATSMGFKK2380 pKa = 10.02KK2381 pKa = 10.62LKK2383 pKa = 9.7ISYY2386 pKa = 8.62TVGIGNEE2393 pKa = 4.01DD2394 pKa = 3.27SDD2396 pKa = 5.6LVMLEE2401 pKa = 3.86CDD2403 pKa = 3.18RR2404 pKa = 11.84PTVHH2408 pKa = 7.82IEE2410 pKa = 3.52FKK2412 pKa = 10.52TYY2414 pKa = 9.57GKK2416 pKa = 9.87QWANLAQIEE2425 pKa = 4.51EE2426 pKa = 4.22YY2427 pKa = 10.7QYY2429 pKa = 10.94IILDD2433 pKa = 3.92EE2434 pKa = 4.14VHH2436 pKa = 6.86VIGDD2440 pKa = 3.88EE2441 pKa = 4.19NVVAMMVHH2449 pKa = 6.73IEE2451 pKa = 4.22TKK2453 pKa = 7.71YY2454 pKa = 9.5HH2455 pKa = 6.36KK2456 pKa = 10.24SNKK2459 pKa = 8.53GVLYY2463 pKa = 10.03MSATHH2468 pKa = 6.9ISNANLYY2475 pKa = 10.18DD2476 pKa = 3.63VAQGEE2481 pKa = 4.71TIAGSPHH2488 pKa = 7.13NITCEE2493 pKa = 3.42SWTIVTDD2500 pKa = 3.88KK2501 pKa = 10.93SDD2503 pKa = 3.65SNAPEE2508 pKa = 3.9GLRR2511 pKa = 11.84NKK2513 pKa = 10.38SRR2515 pKa = 11.84VDD2517 pKa = 3.24RR2518 pKa = 11.84TAGKK2522 pKa = 9.58LHH2524 pKa = 6.68LCSDD2528 pKa = 4.63VIKK2531 pKa = 10.53HH2532 pKa = 5.98KK2533 pKa = 10.64RR2534 pKa = 11.84DD2535 pKa = 3.24DD2536 pKa = 4.62HH2537 pKa = 8.19IVIDD2541 pKa = 3.64MRR2543 pKa = 11.84YY2544 pKa = 8.34ISEE2547 pKa = 3.95KK2548 pKa = 7.8TTVFFCATQRR2558 pKa = 11.84DD2559 pKa = 4.68CEE2561 pKa = 4.44SGASFAQANGITGYY2575 pKa = 10.77AYY2577 pKa = 10.38HH2578 pKa = 7.82ADD2580 pKa = 3.38TKK2582 pKa = 10.73QAVFNSILSEE2592 pKa = 4.42EE2593 pKa = 4.58GTCWVFATNVIQQSVTIPNLVAVVDD2618 pKa = 4.41LGKK2621 pKa = 10.31EE2622 pKa = 3.78CRR2624 pKa = 11.84PQVRR2628 pKa = 11.84ISDD2631 pKa = 4.0CPLQFVCRR2639 pKa = 11.84LQARR2643 pKa = 11.84DD2644 pKa = 3.18TDD2646 pKa = 4.23LNTFVQRR2653 pKa = 11.84KK2654 pKa = 8.13GRR2656 pKa = 11.84VGRR2659 pKa = 11.84TRR2661 pKa = 11.84PGFCISSPNKK2671 pKa = 8.57SHH2673 pKa = 6.91SNRR2676 pKa = 11.84SVEE2679 pKa = 4.83DD2680 pKa = 3.56FVLPYY2685 pKa = 10.62VVLKK2689 pKa = 10.77LLEE2692 pKa = 3.98HH2693 pKa = 6.27HH2694 pKa = 7.1RR2695 pKa = 11.84SLEE2698 pKa = 3.73EE2699 pKa = 3.93LRR2701 pKa = 11.84CHH2703 pKa = 5.76NAEE2706 pKa = 5.94LIDD2709 pKa = 4.2ALQKK2713 pKa = 10.61LSWMSPEE2720 pKa = 3.73NMRR2723 pKa = 11.84EE2724 pKa = 3.95KK2725 pKa = 10.4IATADD2730 pKa = 3.11QDD2732 pKa = 4.43YY2733 pKa = 11.12VCDD2736 pKa = 4.24SLIEE2740 pKa = 3.96KK2741 pKa = 10.24HH2742 pKa = 6.2NRR2744 pKa = 11.84KK2745 pKa = 9.1QYY2747 pKa = 10.74RR2748 pKa = 11.84GVQFDD2753 pKa = 3.68WKK2755 pKa = 10.68IKK2757 pKa = 10.29DD2758 pKa = 3.91SGNKK2762 pKa = 9.46PYY2764 pKa = 11.08DD2765 pKa = 3.52PVKK2768 pKa = 10.49HH2769 pKa = 6.02YY2770 pKa = 10.29LRR2772 pKa = 11.84CWITDD2777 pKa = 3.47SEE2779 pKa = 4.43VSYY2782 pKa = 9.76WCSNGQGVYY2791 pKa = 9.7MKK2793 pKa = 10.51DD2794 pKa = 3.48LIKK2797 pKa = 9.33THH2799 pKa = 6.25PVIKK2803 pKa = 10.38LSEE2806 pKa = 4.03EE2807 pKa = 4.26QEE2809 pKa = 3.83WSEE2812 pKa = 3.91FSSFKK2817 pKa = 10.58DD2818 pKa = 3.23PHH2820 pKa = 6.53DD2821 pKa = 3.85AALLEE2826 pKa = 4.33KK2827 pKa = 10.09EE2828 pKa = 4.81RR2829 pKa = 11.84KK2830 pKa = 10.04GKK2832 pKa = 10.31DD2833 pKa = 2.98DD2834 pKa = 4.22DD2835 pKa = 5.19LRR2837 pKa = 11.84VGDD2840 pKa = 3.89TKK2842 pKa = 11.08EE2843 pKa = 4.21YY2844 pKa = 10.64DD2845 pKa = 3.48DD2846 pKa = 4.22QAALEE2851 pKa = 5.33DD2852 pKa = 3.71ISEE2855 pKa = 4.2MSLAGPFALGLLGLTGAGVIIYY2877 pKa = 8.9EE2878 pKa = 4.7LIDD2881 pKa = 3.86RR2882 pKa = 11.84KK2883 pKa = 10.0CDD2885 pKa = 3.1RR2886 pKa = 11.84YY2887 pKa = 8.03VTHH2890 pKa = 6.22MVSVAEE2896 pKa = 4.03VDD2898 pKa = 3.9VVSCAKK2904 pKa = 10.36FYY2906 pKa = 11.33AEE2908 pKa = 3.94EE2909 pKa = 4.31SLAKK2913 pKa = 9.43MAPQSEE2919 pKa = 4.63NIISALSVLKK2929 pKa = 10.35MMKK2932 pKa = 10.41NEE2934 pKa = 4.02VKK2936 pKa = 10.47HH2937 pKa = 5.27LLRR2940 pKa = 11.84RR2941 pKa = 11.84KK2942 pKa = 7.13TNKK2945 pKa = 9.95LFEE2948 pKa = 4.64LFPWLKK2954 pKa = 10.77PKK2956 pKa = 10.39DD2957 pKa = 3.83KK2958 pKa = 10.38KK2959 pKa = 10.27IKK2961 pKa = 10.21EE2962 pKa = 4.07MSSVDD2967 pKa = 3.0WMSAIEE2973 pKa = 4.32GMLNTAMAAVSNWTATFGMTMGSVFGSLGGGGLLGFIYY3011 pKa = 10.54KK3012 pKa = 10.37DD3013 pKa = 3.29LEE3015 pKa = 4.46KK3016 pKa = 11.53NMGTVLAMVVGAILHH3031 pKa = 5.48GVVFGAMSIKK3041 pKa = 10.41AYY3043 pKa = 10.41GIFAIGQLVTMLVRR3057 pKa = 11.84CVYY3060 pKa = 10.84GNYY3063 pKa = 7.89TRR3065 pKa = 11.84RR3066 pKa = 11.84SGALYY3071 pKa = 9.96TEE3073 pKa = 4.39NHH3075 pKa = 6.13NSGTFWSAIIAGGIGVGFSQVFKK3098 pKa = 9.51QTAMQAACHH3107 pKa = 5.36NQISTVISQASVTTQAGAVGVPILLVKK3134 pKa = 10.47NLYY3137 pKa = 10.44HH3138 pKa = 7.34LFTRR3142 pKa = 11.84AKK3144 pKa = 10.17NFGEE3148 pKa = 4.27IAGSATMVATLILTSSPLTFLYY3170 pKa = 10.63SGAAALTIFGLRR3182 pKa = 11.84CFAEE3186 pKa = 3.95YY3187 pKa = 9.37MIDD3190 pKa = 3.17QAARR3194 pKa = 11.84KK3195 pKa = 8.88EE3196 pKa = 3.81RR3197 pKa = 11.84DD3198 pKa = 3.34GAGGAQHH3205 pKa = 6.85FEE3207 pKa = 3.96EE3208 pKa = 4.42QKK3210 pKa = 10.44RR3211 pKa = 11.84RR3212 pKa = 11.84LRR3214 pKa = 11.84CAVGAVLDD3222 pKa = 3.94AAAVIVYY3229 pKa = 8.35PSSLISVVIGIISEE3243 pKa = 4.13MAMGSTWRR3251 pKa = 11.84DD3252 pKa = 3.02SCEE3255 pKa = 4.13QSWDD3259 pKa = 3.47AYY3261 pKa = 10.91SGVSPFIAAISEE3273 pKa = 3.97IWRR3276 pKa = 11.84HH3277 pKa = 4.84VISFNRR3283 pKa = 11.84NPVSRR3288 pKa = 11.84EE3289 pKa = 3.27EE3290 pKa = 3.97AQQMSITAVSEE3301 pKa = 3.83MWTKK3305 pKa = 9.56FTDD3308 pKa = 3.23LCKK3311 pKa = 10.28RR3312 pKa = 11.84YY3313 pKa = 9.55LGHH3316 pKa = 7.0FNGVGKK3322 pKa = 10.68KK3323 pKa = 9.53IVSTLRR3329 pKa = 11.84KK3330 pKa = 7.99VWDD3333 pKa = 3.56WLVEE3337 pKa = 3.97HH3338 pKa = 6.9LKK3340 pKa = 10.94ACIVQPISSVMSGVVGKK3357 pKa = 8.92CVRR3360 pKa = 11.84DD3361 pKa = 3.71NINNNWLTRR3370 pKa = 11.84SVFRR3374 pKa = 11.84MNDD3377 pKa = 2.85EE3378 pKa = 3.84PAEE3381 pKa = 4.19EE3382 pKa = 4.2KK3383 pKa = 10.44KK3384 pKa = 10.65QYY3386 pKa = 10.09PNPNYY3391 pKa = 10.59SEE3393 pKa = 4.21MSAVMLNRR3401 pKa = 11.84YY3402 pKa = 9.47SEE3404 pKa = 4.32GKK3406 pKa = 8.94MLDD3409 pKa = 4.67LDD3411 pKa = 4.38TFWLDD3416 pKa = 3.19SGAGSVKK3423 pKa = 10.25EE3424 pKa = 4.0YY3425 pKa = 11.27GSMFDD3430 pKa = 3.97NMLISEE3436 pKa = 4.44VTLLRR3441 pKa = 11.84PNKK3444 pKa = 9.37GKK3446 pKa = 10.71KK3447 pKa = 9.28IVTTEE3452 pKa = 3.84PLALYY3457 pKa = 7.88QVPMDD3462 pKa = 4.66KK3463 pKa = 10.73LLEE3466 pKa = 4.19LLNLTVANCQIKK3478 pKa = 9.85NNVMEE3483 pKa = 4.49FDD3485 pKa = 3.89VPTGSSACPVVKK3497 pKa = 10.72VSFTNTFSEE3506 pKa = 4.87GSMLACIKK3514 pKa = 10.55HH3515 pKa = 5.8KK3516 pKa = 10.92APVFAGYY3523 pKa = 9.72WLMWFYY3529 pKa = 11.39RR3530 pKa = 11.84NYY3532 pKa = 10.62QGATEE3537 pKa = 4.12INIIEE3542 pKa = 4.39YY3543 pKa = 10.71GDD3545 pKa = 3.41TDD3547 pKa = 5.16GITDD3551 pKa = 3.55QLLATLQAQCSLLAGQPKK3569 pKa = 9.9EE3570 pKa = 3.77LTEE3573 pKa = 4.47RR3574 pKa = 11.84EE3575 pKa = 4.15FLNLHH3580 pKa = 6.06EE3581 pKa = 4.54SLFRR3585 pKa = 11.84VEE3587 pKa = 4.99LPRR3590 pKa = 11.84TSVFSQMLHH3599 pKa = 3.9VTKK3602 pKa = 10.76SKK3604 pKa = 10.23VLNMMTEE3611 pKa = 3.71WPDD3614 pKa = 3.3QLRR3617 pKa = 11.84EE3618 pKa = 3.96RR3619 pKa = 11.84VKK3621 pKa = 10.94VKK3623 pKa = 10.57HH3624 pKa = 6.14PLNFSYY3630 pKa = 10.81LHH3632 pKa = 6.02FLNIKK3637 pKa = 10.33DD3638 pKa = 3.84MSSEE3642 pKa = 4.02EE3643 pKa = 4.0AKK3645 pKa = 10.88QMLDD3649 pKa = 3.22YY3650 pKa = 10.81CRR3652 pKa = 11.84YY3653 pKa = 6.55WQYY3656 pKa = 11.81YY3657 pKa = 8.95IIKK3660 pKa = 9.25CQNLYY3665 pKa = 10.75CRR3667 pKa = 11.84LSNTEE3672 pKa = 3.88YY3673 pKa = 10.96KK3674 pKa = 9.97SPKK3677 pKa = 8.59WNIPQGAQVHH3687 pKa = 5.29WMNVEE3692 pKa = 4.04NPAEE3696 pKa = 4.71PDD3698 pKa = 3.42TAGHH3702 pKa = 6.99ISAQLGCQLIRR3713 pKa = 11.84PGYY3716 pKa = 8.61SSYY3719 pKa = 10.9WDD3721 pKa = 3.61TPLLLTSNKK3730 pKa = 10.14SLTHH3734 pKa = 6.71RR3735 pKa = 11.84LLEE3738 pKa = 4.24LVSVNYY3744 pKa = 9.46EE3745 pKa = 3.51INVRR3749 pKa = 11.84YY3750 pKa = 8.72CHH3752 pKa = 7.01RR3753 pKa = 11.84GANDD3757 pKa = 2.93QWIEE3761 pKa = 3.71EE3762 pKa = 4.23WVICGSTCPKK3772 pKa = 10.45HH3773 pKa = 6.46FISLIYY3779 pKa = 10.82DD3780 pKa = 3.71GDD3782 pKa = 3.75DD3783 pKa = 3.0HH3784 pKa = 7.31FIRR3787 pKa = 11.84MPDD3790 pKa = 3.48CAIIDD3795 pKa = 4.06HH3796 pKa = 5.88CHH3798 pKa = 5.44KK3799 pKa = 9.06TPNVAFISKK3808 pKa = 9.8FAEE3811 pKa = 3.79FDD3813 pKa = 3.0IVMAEE3818 pKa = 4.13FVRR3821 pKa = 11.84DD3822 pKa = 3.24GDD3824 pKa = 4.05RR3825 pKa = 11.84IFTYY3829 pKa = 9.14EE3830 pKa = 4.77HH3831 pKa = 6.6INKK3834 pKa = 9.24IPLARR3839 pKa = 11.84AVSKK3843 pKa = 11.15FEE3845 pKa = 4.34LQVQEE3850 pKa = 3.91QSKK3853 pKa = 10.84KK3854 pKa = 9.28IVQPGTTRR3862 pKa = 11.84TNQVMTLLQDD3872 pKa = 4.01FSRR3875 pKa = 11.84KK3876 pKa = 9.73LGEE3879 pKa = 3.84KK3880 pKa = 10.15SRR3882 pKa = 11.84LVWTQLGDD3890 pKa = 3.27IAKK3893 pKa = 9.69VVAEE3897 pKa = 4.61TRR3899 pKa = 11.84PSDD3902 pKa = 3.27IVEE3905 pKa = 4.25ASTSIITKK3913 pKa = 10.5AIVHH3917 pKa = 6.47KK3918 pKa = 11.13SNDD3921 pKa = 3.39EE3922 pKa = 4.05GEE3924 pKa = 4.34EE3925 pKa = 3.89MSASLFQSFSDD3936 pKa = 3.45LLKK3939 pKa = 10.33IYY3941 pKa = 10.61FSGQDD3946 pKa = 3.2QRR3948 pKa = 11.84VSPNKK3953 pKa = 9.77VDD3955 pKa = 4.34DD3956 pKa = 4.34DD3957 pKa = 4.29ALIEE3961 pKa = 4.14RR3962 pKa = 11.84VNFFLTAAQQKK3973 pKa = 8.85EE3974 pKa = 4.22LLIEE3978 pKa = 4.38RR3979 pKa = 11.84CPTYY3983 pKa = 10.61EE3984 pKa = 4.18SIRR3987 pKa = 11.84ASSEE3991 pKa = 3.51LDD3993 pKa = 3.05TEE3995 pKa = 4.65MEE3997 pKa = 4.29FEE3999 pKa = 4.75DD4000 pKa = 4.38ADD4002 pKa = 4.53SVRR4005 pKa = 11.84LLDD4008 pKa = 3.59NCAVIGFTEE4017 pKa = 4.32ASKK4020 pKa = 11.13GRR4022 pKa = 11.84VPHH4025 pKa = 4.66WTWYY4029 pKa = 9.39KK4030 pKa = 11.09AEE4032 pKa = 4.57DD4033 pKa = 3.28ASKK4036 pKa = 10.33FRR4038 pKa = 11.84RR4039 pKa = 11.84EE4040 pKa = 4.36SITTVAPSDD4049 pKa = 3.69VMALYY4054 pKa = 10.47KK4055 pKa = 10.47KK4056 pKa = 10.92LNDD4059 pKa = 3.28RR4060 pKa = 11.84CISKK4064 pKa = 10.38RR4065 pKa = 11.84QWEE4068 pKa = 4.33KK4069 pKa = 10.68LRR4071 pKa = 11.84YY4072 pKa = 8.12ADD4074 pKa = 4.81RR4075 pKa = 11.84YY4076 pKa = 9.65RR4077 pKa = 11.84LPSSLEE4083 pKa = 3.54QKK4085 pKa = 10.92ANEE4088 pKa = 4.06EE4089 pKa = 4.06VKK4091 pKa = 9.73ACSRR4095 pKa = 11.84AFYY4098 pKa = 10.97KK4099 pKa = 9.54MQQLFEE4105 pKa = 5.17ADD4107 pKa = 3.11PAFFEE4112 pKa = 4.39NCHH4115 pKa = 6.57TILDD4119 pKa = 4.26PACGYY4124 pKa = 11.14GGFSQYY4130 pKa = 11.16LSNKK4134 pKa = 8.49LASGAPKK4141 pKa = 9.93TILAGSLIQKK4151 pKa = 7.2GHH4153 pKa = 7.72RR4154 pKa = 11.84IPDD4157 pKa = 3.49MSRR4160 pKa = 11.84LTAHH4164 pKa = 7.15GSNVRR4169 pKa = 11.84VVNLCRR4175 pKa = 11.84PDD4177 pKa = 4.32LDD4179 pKa = 5.14NGDD4182 pKa = 4.56LRR4184 pKa = 11.84NKK4186 pKa = 9.31MVLNRR4191 pKa = 11.84YY4192 pKa = 7.62LHH4194 pKa = 6.41EE4195 pKa = 4.13SHH4197 pKa = 6.87KK4198 pKa = 10.83FEE4200 pKa = 5.48GMDD4203 pKa = 3.9LVLYY4207 pKa = 11.01DD4208 pKa = 3.52MGEE4211 pKa = 3.98FFDD4214 pKa = 4.67NSKK4217 pKa = 10.91DD4218 pKa = 3.69QYY4220 pKa = 11.34NWWTKK4225 pKa = 7.22PAKK4228 pKa = 10.29DD4229 pKa = 3.32ISEE4232 pKa = 4.58DD4233 pKa = 3.62NQVSLIEE4240 pKa = 4.57GMATLLKK4247 pKa = 9.46TLRR4250 pKa = 11.84AGGRR4254 pKa = 11.84MLLKK4258 pKa = 7.52WTGYY4262 pKa = 9.52FGCGDD4267 pKa = 3.85EE4268 pKa = 5.35LLQKK4272 pKa = 10.83LLSCFKK4278 pKa = 10.15NFKK4281 pKa = 9.69AIKK4284 pKa = 9.56VGTSSLYY4291 pKa = 7.59TTEE4294 pKa = 4.38FYY4296 pKa = 10.24IYY4298 pKa = 10.52ASGYY4302 pKa = 8.53TGLTSTSVGRR4312 pKa = 11.84VRR4314 pKa = 11.84RR4315 pKa = 11.84FYY4317 pKa = 11.33EE4318 pKa = 4.3EE4319 pKa = 3.65IGEE4322 pKa = 4.47CIYY4325 pKa = 11.08SQLIRR4330 pKa = 11.84ANHH4333 pKa = 5.41IMMHH4337 pKa = 6.29PSYY4340 pKa = 9.6YY4341 pKa = 9.91PPMEE4345 pKa = 5.1RR4346 pKa = 11.84GDD4348 pKa = 3.6WEE4350 pKa = 4.56YY4351 pKa = 10.3PASTGVVYY4359 pKa = 10.5RR4360 pKa = 11.84ADD4362 pKa = 3.48ANEE4365 pKa = 3.75NRR4367 pKa = 11.84PGGIEE4372 pKa = 3.99WEE4374 pKa = 3.82LHH4376 pKa = 5.13YY4377 pKa = 10.8AGKK4380 pKa = 9.93VLKK4383 pKa = 10.04EE4384 pKa = 3.57SWMPNWDD4391 pKa = 3.3EE4392 pKa = 3.78RR4393 pKa = 11.84HH4394 pKa = 6.23QIFQQVVRR4402 pKa = 11.84RR4403 pKa = 11.84EE4404 pKa = 4.31LYY4406 pKa = 10.24RR4407 pKa = 11.84EE4408 pKa = 3.87TPTRR4412 pKa = 11.84RR4413 pKa = 11.84LRR4415 pKa = 11.84YY4416 pKa = 9.43NRR4418 pKa = 11.84GSNGTYY4424 pKa = 10.33SKK4426 pKa = 10.62LYY4428 pKa = 8.27QDD4430 pKa = 4.13GWFSRR4435 pKa = 11.84PVKK4438 pKa = 10.25NVHH4441 pKa = 6.02EE4442 pKa = 4.31KK4443 pKa = 10.5HH4444 pKa = 6.77SKK4446 pKa = 10.34NDD4448 pKa = 3.8LLNSLCYY4455 pKa = 9.76FVTKK4459 pKa = 8.62TTDD4462 pKa = 3.31DD4463 pKa = 3.86NSTMGQCQATKK4474 pKa = 9.77EE4475 pKa = 3.85YY4476 pKa = 10.83RR4477 pKa = 11.84EE4478 pKa = 3.98ASIKK4482 pKa = 10.48KK4483 pKa = 10.04RR4484 pKa = 11.84IDD4486 pKa = 3.12FEE4488 pKa = 5.25APVLPGYY4495 pKa = 9.93VLEE4498 pKa = 4.54EE4499 pKa = 3.77LAEE4502 pKa = 4.27ILDD4505 pKa = 4.51LMTTEE4510 pKa = 4.02YY4511 pKa = 11.2GKK4513 pKa = 9.12TIEE4516 pKa = 4.47GKK4518 pKa = 10.27CRR4520 pKa = 11.84LLTKK4524 pKa = 10.41EE4525 pKa = 4.12EE4526 pKa = 4.69VYY4528 pKa = 11.69VMLNKK4533 pKa = 10.47NGATSILSKK4542 pKa = 10.62DD4543 pKa = 3.45ANLRR4547 pKa = 11.84NYY4549 pKa = 10.03MEE4551 pKa = 4.45THH4553 pKa = 6.21PNWYY4557 pKa = 8.46EE4558 pKa = 3.76LSMHH4562 pKa = 5.92YY4563 pKa = 10.27CVNRR4567 pKa = 11.84WRR4569 pKa = 11.84KK4570 pKa = 7.81NQPTHH4575 pKa = 5.7GFFNIMHH4582 pKa = 6.55KK4583 pKa = 10.93NEE4585 pKa = 4.03AKK4587 pKa = 10.28AKK4589 pKa = 10.33KK4590 pKa = 9.88NVEE4593 pKa = 3.84QGNICLEE4600 pKa = 4.29RR4601 pKa = 11.84GSDD4604 pKa = 3.31MKK4606 pKa = 11.32YY4607 pKa = 10.42EE4608 pKa = 4.23PDD4610 pKa = 3.41EE4611 pKa = 4.11LRR4613 pKa = 11.84EE4614 pKa = 3.93EE4615 pKa = 4.15LKK4617 pKa = 10.19TYY4619 pKa = 11.25NNLPHH4624 pKa = 7.26RR4625 pKa = 11.84FIQYY4629 pKa = 9.63ADD4631 pKa = 3.93EE4632 pKa = 4.14ITRR4635 pKa = 11.84IAHH4638 pKa = 5.69YY4639 pKa = 10.14IILGDD4644 pKa = 4.49LIEE4647 pKa = 4.92KK4648 pKa = 10.73NSIQKK4653 pKa = 9.82IYY4655 pKa = 10.34KK4656 pKa = 8.48GTVNGCPPAYY4666 pKa = 10.11LGNVLRR4672 pKa = 11.84AAWDD4676 pKa = 3.77LNEE4679 pKa = 5.08PNDD4682 pKa = 3.54KK4683 pKa = 10.84HH4684 pKa = 7.7KK4685 pKa = 11.27VFTATHH4691 pKa = 5.91VDD4693 pKa = 3.38GKK4695 pKa = 9.95HH4696 pKa = 5.39VKK4698 pKa = 8.9EE4699 pKa = 3.77QAGANINVYY4708 pKa = 9.47TSSQLPEE4715 pKa = 3.93GVAPHH4720 pKa = 7.09EE4721 pKa = 4.46DD4722 pKa = 3.86DD4723 pKa = 4.42KK4724 pKa = 11.85PCGLSIDD4731 pKa = 3.8YY4732 pKa = 10.64SSWDD4736 pKa = 3.26GSVSVGEE4743 pKa = 4.85RR4744 pKa = 11.84MLEE4747 pKa = 4.0ANKK4750 pKa = 10.03LASFYY4755 pKa = 10.13PPGMRR4760 pKa = 11.84STIMNACRR4768 pKa = 11.84EE4769 pKa = 4.1MAFAICLDD4777 pKa = 3.43HH4778 pKa = 7.7DD4779 pKa = 4.63GNVCYY4784 pKa = 10.36RR4785 pKa = 11.84SGHH4788 pKa = 5.91RR4789 pKa = 11.84GSGEE4793 pKa = 3.64ILTSIGNTQLVAANTIRR4810 pKa = 11.84AICKK4814 pKa = 9.99VLGLTFKK4821 pKa = 10.68EE4822 pKa = 3.97ALQNRR4827 pKa = 11.84AVITAKK4833 pKa = 10.37VGQKK4837 pKa = 8.59TKK4839 pKa = 9.72IYY4841 pKa = 8.98EE4842 pKa = 4.07VTRR4845 pKa = 11.84IPQFSDD4851 pKa = 3.19GDD4853 pKa = 3.81DD4854 pKa = 3.6TVILTTRR4861 pKa = 11.84RR4862 pKa = 11.84IAKK4865 pKa = 9.58LIEE4868 pKa = 3.87MNIDD4872 pKa = 3.27EE4873 pKa = 4.86EE4874 pKa = 4.44LAIAGKK4880 pKa = 10.22KK4881 pKa = 8.76IRR4883 pKa = 11.84SGTKK4887 pKa = 9.58SGCSKK4892 pKa = 10.54HH4893 pKa = 6.78DD4894 pKa = 3.26QFKK4897 pKa = 9.07TLEE4900 pKa = 4.49FCSHH4904 pKa = 6.3TYY4906 pKa = 10.73EE4907 pKa = 4.96SILVGKK4913 pKa = 8.19QAQYY4917 pKa = 10.12VSCMPHH4923 pKa = 4.29QHH4925 pKa = 7.13RR4926 pKa = 11.84SLCEE4930 pKa = 3.63NFPEE4934 pKa = 4.24FRR4936 pKa = 11.84IRR4938 pKa = 11.84HH4939 pKa = 5.55LPTRR4943 pKa = 11.84PTTDD4947 pKa = 2.58IIGKK4951 pKa = 9.04LRR4953 pKa = 11.84ATLKK4957 pKa = 10.65QSAFKK4962 pKa = 10.67YY4963 pKa = 9.69KK4964 pKa = 10.62HH4965 pKa = 6.55EE4966 pKa = 5.47DD4967 pKa = 3.5DD4968 pKa = 4.68SPTGSKK4974 pKa = 9.97ILTRR4978 pKa = 11.84SKK4980 pKa = 10.72LLSYY4984 pKa = 10.88LLLYY4988 pKa = 7.22PHH4990 pKa = 6.84CRR4992 pKa = 11.84YY4993 pKa = 9.58VRR4995 pKa = 11.84YY4996 pKa = 9.84LCLSGLIVTGDD5007 pKa = 3.27GTVNFDD5013 pKa = 3.23EE5014 pKa = 4.97MIRR5017 pKa = 11.84RR5018 pKa = 11.84YY5019 pKa = 9.5PDD5021 pKa = 2.92YY5022 pKa = 10.97RR5023 pKa = 11.84FVLGKK5028 pKa = 6.47TTLMGALDD5036 pKa = 3.9SVYY5039 pKa = 10.87GVATFDD5045 pKa = 4.59DD5046 pKa = 3.93VGLRR5050 pKa = 11.84QYY5052 pKa = 11.73NDD5054 pKa = 3.45DD5055 pKa = 4.16KK5056 pKa = 11.53RR5057 pKa = 11.84DD5058 pKa = 3.33GRR5060 pKa = 11.84QLRR5063 pKa = 11.84RR5064 pKa = 11.84HH5065 pKa = 5.96AKK5067 pKa = 10.44LIGEE5071 pKa = 4.28VLDD5074 pKa = 4.27IRR5076 pKa = 11.84LQSIVSKK5083 pKa = 11.16AMVWTTNYY5091 pKa = 10.28KK5092 pKa = 9.96FRR5094 pKa = 11.84DD5095 pKa = 3.58WTVAAHH5101 pKa = 7.01DD5102 pKa = 4.17SKK5104 pKa = 10.52FCKK5107 pKa = 9.95MIWKK5111 pKa = 10.06SIITRR5116 pKa = 11.84QVRR5119 pKa = 11.84LFPSEE5124 pKa = 3.29IRR5126 pKa = 11.84QIKK5129 pKa = 10.26SNLDD5133 pKa = 3.24LTKK5136 pKa = 9.83TQIEE5140 pKa = 4.3IPDD5143 pKa = 3.51EE5144 pKa = 4.41SVYY5147 pKa = 10.07STSEE5151 pKa = 3.59EE5152 pKa = 3.86AGILTNYY5159 pKa = 10.21QSDD5162 pKa = 3.63NKK5164 pKa = 11.17SNLNWLSKK5172 pKa = 10.95LFLL5175 pKa = 4.8

Molecular weight: 582.76 kDa
Isoelectric point according different methods:

Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try ESI

ChTry ESI

ArgC ESI

LysN ESI

TryLysC ESI

Try MALDI

ChTry MALDI

ArgC MALDI

LysN MALDI

TryLysC MALDI

Try LTQ

ChTry LTQ

ArgC LTQ

LysN LTQ

TryLysC LTQ

Try MSlow

ChTry MSlow

ArgC MSlow

LysN MSlow

TryLysC MSlow

Try MShigh

ChTry MShigh

ArgC MShigh

LysN MShigh

TryLysC MShigh

General Statistics

Number of major isoforms	Number of additional isoforms	Number of all proteins	Number of amino acids	Min. Seq. Length	Max. Seq. Length	Avg. Seq. Length	Avg. Mol. Weight
1	0	1	5175	5175	5175	5175.0	582.76

Amino acid frequency

Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu
6.725 ± 0.0	2.841 ± 0.0	5.469 ± 0.0	5.604 ± 0.0	4.077 ± 0.0	6.087 ± 0.0	2.667 ± 0.0	6.667 ± 0.0	6.802 ± 0.0	8.271 ± 0.0

Met	Asn	Gln	Pro	Arg	Ser	Thr	Val	Trp	Tyr
2.531 ± 0.0	5.179 ± 0.0	3.343 ± 0.0	3.246 ± 0.0	4.773 ± 0.0	7.362 ± 0.0	6.048 ± 0.0	6.957 ± 0.0	1.604 ± 0.0	3.749 ± 0.0

Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here

See this proteome in:

Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski