Amino acid dipepetide frequency for Tetterwort vein chlorosis virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.607AlaAla: 2.607 ± 0.532
0.201AlaCys: 0.201 ± 0.241
2.407AlaAsp: 2.407 ± 0.714
1.805AlaGlu: 1.805 ± 0.444
2.206AlaPhe: 2.206 ± 0.37
2.407AlaGly: 2.407 ± 0.969
0.602AlaHis: 0.602 ± 0.319
2.607AlaIle: 2.607 ± 0.918
3.61AlaLys: 3.61 ± 0.616
4.212AlaLeu: 4.212 ± 0.772
0.602AlaMet: 0.602 ± 0.342
2.607AlaAsn: 2.607 ± 0.528
0.602AlaPro: 0.602 ± 0.316
1.805AlaGln: 1.805 ± 0.479
2.808AlaArg: 2.808 ± 0.624
1.604AlaSer: 1.604 ± 0.551
2.206AlaThr: 2.206 ± 0.711
3.209AlaVal: 3.209 ± 1.124
0.0AlaTrp: 0.0 ± 0.0
1.003AlaTyr: 1.003 ± 0.504
0.0AlaXaa: 0.0 ± 0.0
Cys
0.401CysAla: 0.401 ± 0.433
0.401CysCys: 0.401 ± 0.272
2.206CysAsp: 2.206 ± 0.679
0.602CysGlu: 0.602 ± 0.351
1.003CysPhe: 1.003 ± 0.537
1.203CysGly: 1.203 ± 0.506
0.802CysHis: 0.802 ± 0.436
1.604CysIle: 1.604 ± 0.664
1.604CysLys: 1.604 ± 0.508
2.206CysLeu: 2.206 ± 0.737
0.602CysMet: 0.602 ± 0.485
1.003CysAsn: 1.003 ± 0.408
0.201CysPro: 0.201 ± 0.136
0.401CysGln: 0.401 ± 0.259
1.003CysArg: 1.003 ± 0.466
2.206CysSer: 2.206 ± 0.638
1.003CysThr: 1.003 ± 0.272
2.407CysVal: 2.407 ± 0.841
0.401CysTrp: 0.401 ± 0.259
0.802CysTyr: 0.802 ± 0.351
0.0CysXaa: 0.0 ± 0.0
Asp
2.206AspAla: 2.206 ± 0.555
0.602AspCys: 0.602 ± 0.249
4.813AspAsp: 4.813 ± 1.266
3.008AspGlu: 3.008 ± 0.617
6.418AspPhe: 6.418 ± 1.276
3.61AspGly: 3.61 ± 0.457
0.602AspHis: 0.602 ± 0.303
5.215AspIle: 5.215 ± 0.784
5.215AspLys: 5.215 ± 0.88
5.616AspLeu: 5.616 ± 2.089
1.003AspMet: 1.003 ± 0.432
4.212AspAsn: 4.212 ± 1.099
1.604AspPro: 1.604 ± 0.701
0.401AspGln: 0.401 ± 0.365
3.008AspArg: 3.008 ± 0.799
4.212AspSer: 4.212 ± 0.653
3.008AspThr: 3.008 ± 0.986
5.816AspVal: 5.816 ± 0.696
1.203AspTrp: 1.203 ± 0.509
3.41AspTyr: 3.41 ± 0.723
0.0AspXaa: 0.0 ± 0.0
Glu
1.404GluAla: 1.404 ± 0.425
0.802GluCys: 0.802 ± 0.479
3.209GluAsp: 3.209 ± 0.593
4.212GluGlu: 4.212 ± 0.721
3.008GluPhe: 3.008 ± 0.814
3.209GluGly: 3.209 ± 0.875
0.802GluHis: 0.802 ± 0.412
4.613GluIle: 4.613 ± 0.76
4.412GluLys: 4.412 ± 0.905
5.014GluLeu: 5.014 ± 1.508
1.203GluMet: 1.203 ± 0.357
3.61GluAsn: 3.61 ± 0.692
1.805GluPro: 1.805 ± 0.464
0.602GluGln: 0.602 ± 0.509
3.008GluArg: 3.008 ± 0.826
2.808GluSer: 2.808 ± 0.797
2.006GluThr: 2.006 ± 0.419
2.407GluVal: 2.407 ± 0.808
1.003GluTrp: 1.003 ± 0.404
2.407GluTyr: 2.407 ± 1.108
0.0GluXaa: 0.0 ± 0.0
Phe
2.006PheAla: 2.006 ± 0.413
1.805PheCys: 1.805 ± 0.672
4.011PheAsp: 4.011 ± 1.419
3.41PheGlu: 3.41 ± 0.928
3.41PhePhe: 3.41 ± 1.177
2.006PheGly: 2.006 ± 0.517
0.802PheHis: 0.802 ± 0.415
3.61PheIle: 3.61 ± 0.91
4.813PheLys: 4.813 ± 1.608
5.215PheLeu: 5.215 ± 1.627
2.006PheMet: 2.006 ± 0.512
4.011PheAsn: 4.011 ± 1.13
1.203PhePro: 1.203 ± 0.545
1.404PheGln: 1.404 ± 0.459
2.206PheArg: 2.206 ± 0.725
6.819PheSer: 6.819 ± 1.088
3.811PheThr: 3.811 ± 0.91
3.41PheVal: 3.41 ± 0.881
0.401PheTrp: 0.401 ± 0.399
2.407PheTyr: 2.407 ± 1.09
0.0PheXaa: 0.0 ± 0.0
Gly
1.805GlyAla: 1.805 ± 0.771
1.203GlyCys: 1.203 ± 0.329
3.61GlyAsp: 3.61 ± 0.712
3.209GlyGlu: 3.209 ± 0.495
2.407GlyPhe: 2.407 ± 1.047
4.813GlyGly: 4.813 ± 1.225
1.003GlyHis: 1.003 ± 0.603
3.209GlyIle: 3.209 ± 0.653
4.011GlyLys: 4.011 ± 0.799
2.808GlyLeu: 2.808 ± 0.765
1.003GlyMet: 1.003 ± 0.319
2.006GlyAsn: 2.006 ± 0.561
1.404GlyPro: 1.404 ± 0.63
1.203GlyGln: 1.203 ± 0.274
3.209GlyArg: 3.209 ± 0.878
2.808GlySer: 2.808 ± 0.663
2.006GlyThr: 2.006 ± 0.521
4.212GlyVal: 4.212 ± 0.783
0.802GlyTrp: 0.802 ± 0.312
1.604GlyTyr: 1.604 ± 0.671
0.0GlyXaa: 0.0 ± 0.0
His
0.802HisAla: 0.802 ± 0.351
0.602HisCys: 0.602 ± 0.294
1.203HisAsp: 1.203 ± 0.392
1.404HisGlu: 1.404 ± 0.49
1.404HisPhe: 1.404 ± 0.479
1.203HisGly: 1.203 ± 0.658
0.401HisHis: 0.401 ± 0.259
1.203HisIle: 1.203 ± 0.679
1.604HisLys: 1.604 ± 0.487
2.607HisLeu: 2.607 ± 0.771
0.401HisMet: 0.401 ± 0.289
1.003HisAsn: 1.003 ± 0.368
1.003HisPro: 1.003 ± 0.421
0.201HisGln: 0.201 ± 0.241
0.602HisArg: 0.602 ± 0.322
0.602HisSer: 0.602 ± 0.408
2.006HisThr: 2.006 ± 0.567
1.404HisVal: 1.404 ± 0.693
0.0HisTrp: 0.0 ± 0.0
0.802HisTyr: 0.802 ± 0.258
0.0HisXaa: 0.0 ± 0.0
Ile
2.206IleAla: 2.206 ± 1.156
1.203IleCys: 1.203 ± 0.515
4.212IleAsp: 4.212 ± 0.944
3.209IleGlu: 3.209 ± 0.81
3.61IlePhe: 3.61 ± 0.998
2.407IleGly: 2.407 ± 1.105
1.604IleHis: 1.604 ± 0.567
5.816IleIle: 5.816 ± 1.036
4.813IleLys: 4.813 ± 0.891
6.017IleLeu: 6.017 ± 1.072
1.604IleMet: 1.604 ± 0.623
5.415IleAsn: 5.415 ± 0.979
3.61IlePro: 3.61 ± 0.553
1.003IleGln: 1.003 ± 0.421
1.404IleArg: 1.404 ± 0.686
8.624IleSer: 8.624 ± 1.058
3.61IleThr: 3.61 ± 0.764
4.011IleVal: 4.011 ± 1.024
0.802IleTrp: 0.802 ± 0.377
3.008IleTyr: 3.008 ± 0.632
0.0IleXaa: 0.0 ± 0.0
Lys
3.209LysAla: 3.209 ± 0.715
2.407LysCys: 2.407 ± 0.552
4.212LysAsp: 4.212 ± 1.153
3.811LysGlu: 3.811 ± 0.741
5.215LysPhe: 5.215 ± 0.831
3.811LysGly: 3.811 ± 0.514
1.003LysHis: 1.003 ± 0.579
6.017LysIle: 6.017 ± 1.023
5.616LysLys: 5.616 ± 1.305
6.217LysLeu: 6.217 ± 0.878
2.407LysMet: 2.407 ± 1.105
4.212LysAsn: 4.212 ± 1.287
2.808LysPro: 2.808 ± 1.91
3.811LysGln: 3.811 ± 1.117
5.014LysArg: 5.014 ± 1.009
6.017LysSer: 6.017 ± 0.766
4.212LysThr: 4.212 ± 0.674
4.212LysVal: 4.212 ± 1.03
0.201LysTrp: 0.201 ± 0.241
2.607LysTyr: 2.607 ± 1.035
0.0LysXaa: 0.0 ± 0.0
Leu
4.212LeuAla: 4.212 ± 0.588
2.407LeuCys: 2.407 ± 0.832
5.616LeuAsp: 5.616 ± 1.05
4.412LeuGlu: 4.412 ± 0.966
6.217LeuPhe: 6.217 ± 1.054
3.41LeuGly: 3.41 ± 0.878
1.404LeuHis: 1.404 ± 0.527
6.819LeuIle: 6.819 ± 1.774
8.825LeuLys: 8.825 ± 1.616
8.223LeuLeu: 8.223 ± 1.687
3.61LeuMet: 3.61 ± 0.581
5.415LeuAsn: 5.415 ± 1.423
3.008LeuPro: 3.008 ± 1.017
3.008LeuGln: 3.008 ± 0.782
5.816LeuArg: 5.816 ± 0.84
7.421LeuSer: 7.421 ± 1.419
4.011LeuThr: 4.011 ± 1.303
6.819LeuVal: 6.819 ± 0.925
0.201LeuTrp: 0.201 ± 0.241
4.212LeuTyr: 4.212 ± 0.837
0.0LeuXaa: 0.0 ± 0.0
Met
1.604MetAla: 1.604 ± 0.431
0.602MetCys: 0.602 ± 0.343
2.407MetAsp: 2.407 ± 1.003
0.802MetGlu: 0.802 ± 0.341
2.006MetPhe: 2.006 ± 0.883
0.802MetGly: 0.802 ± 0.412
0.0MetHis: 0.0 ± 0.0
1.404MetIle: 1.404 ± 0.487
2.607MetLys: 2.607 ± 0.796
2.206MetLeu: 2.206 ± 0.785
0.802MetMet: 0.802 ± 0.505
2.407MetAsn: 2.407 ± 1.02
0.401MetPro: 0.401 ± 0.235
0.802MetGln: 0.802 ± 0.544
2.206MetArg: 2.206 ± 0.711
1.604MetSer: 1.604 ± 0.475
2.607MetThr: 2.607 ± 0.504
1.805MetVal: 1.805 ± 0.5
0.0MetTrp: 0.0 ± 0.0
1.404MetTyr: 1.404 ± 0.523
0.0MetXaa: 0.0 ± 0.0
Asn
2.407AsnAla: 2.407 ± 0.997
0.802AsnCys: 0.802 ± 0.351
3.008AsnAsp: 3.008 ± 0.803
2.607AsnGlu: 2.607 ± 0.599
4.011AsnPhe: 4.011 ± 1.08
2.808AsnGly: 2.808 ± 0.855
0.401AsnHis: 0.401 ± 0.341
5.215AsnIle: 5.215 ± 1.509
4.813AsnLys: 4.813 ± 0.9
6.819AsnLeu: 6.819 ± 1.274
2.006AsnMet: 2.006 ± 0.551
4.212AsnAsn: 4.212 ± 1.985
2.607AsnPro: 2.607 ± 0.845
2.607AsnGln: 2.607 ± 0.77
3.61AsnArg: 3.61 ± 0.816
3.811AsnSer: 3.811 ± 1.153
3.008AsnThr: 3.008 ± 0.884
6.217AsnVal: 6.217 ± 1.168
0.401AsnTrp: 0.401 ± 0.272
2.206AsnTyr: 2.206 ± 0.536
0.0AsnXaa: 0.0 ± 0.0
Pro
1.604ProAla: 1.604 ± 0.916
0.602ProCys: 0.602 ± 0.306
1.805ProAsp: 1.805 ± 0.577
1.805ProGlu: 1.805 ± 0.868
1.604ProPhe: 1.604 ± 0.561
1.604ProGly: 1.604 ± 0.47
1.203ProHis: 1.203 ± 0.44
1.203ProIle: 1.203 ± 0.499
3.209ProLys: 3.209 ± 0.894
2.407ProLeu: 2.407 ± 0.684
1.404ProMet: 1.404 ± 0.471
2.808ProAsn: 2.808 ± 0.93
1.805ProPro: 1.805 ± 0.667
0.802ProGln: 0.802 ± 0.565
1.404ProArg: 1.404 ± 0.521
2.006ProSer: 2.006 ± 0.429
1.805ProThr: 1.805 ± 0.54
1.203ProVal: 1.203 ± 0.454
0.201ProTrp: 0.201 ± 0.244
0.802ProTyr: 0.802 ± 0.254
0.0ProXaa: 0.0 ± 0.0
Gln
1.003GlnAla: 1.003 ± 0.54
1.003GlnCys: 1.003 ± 0.562
1.604GlnAsp: 1.604 ± 0.545
0.802GlnGlu: 0.802 ± 0.415
1.805GlnPhe: 1.805 ± 0.467
1.203GlnGly: 1.203 ± 0.468
0.602GlnHis: 0.602 ± 0.264
1.203GlnIle: 1.203 ± 0.636
1.203GlnLys: 1.203 ± 0.751
3.811GlnLeu: 3.811 ± 0.777
0.802GlnMet: 0.802 ± 0.426
2.006GlnAsn: 2.006 ± 0.733
0.802GlnPro: 0.802 ± 0.483
0.602GlnGln: 0.602 ± 0.304
2.006GlnArg: 2.006 ± 0.525
2.006GlnSer: 2.006 ± 0.665
1.805GlnThr: 1.805 ± 0.424
1.003GlnVal: 1.003 ± 0.368
0.401GlnTrp: 0.401 ± 0.488
1.604GlnTyr: 1.604 ± 0.477
0.0GlnXaa: 0.0 ± 0.0
Arg
2.006ArgAla: 2.006 ± 0.666
1.003ArgCys: 1.003 ± 0.574
4.011ArgAsp: 4.011 ± 0.715
2.407ArgGlu: 2.407 ± 0.454
3.008ArgPhe: 3.008 ± 0.778
1.805ArgGly: 1.805 ± 0.525
1.805ArgHis: 1.805 ± 0.654
2.407ArgIle: 2.407 ± 0.837
1.604ArgLys: 1.604 ± 0.68
6.017ArgLeu: 6.017 ± 1.325
2.206ArgMet: 2.206 ± 0.442
3.61ArgAsn: 3.61 ± 0.683
1.604ArgPro: 1.604 ± 0.491
1.604ArgGln: 1.604 ± 0.632
2.808ArgArg: 2.808 ± 0.575
4.011ArgSer: 4.011 ± 1.149
3.811ArgThr: 3.811 ± 1.36
4.813ArgVal: 4.813 ± 1.122
0.602ArgTrp: 0.602 ± 0.252
2.407ArgTyr: 2.407 ± 0.78
0.0ArgXaa: 0.0 ± 0.0
Ser
3.61SerAla: 3.61 ± 0.812
0.802SerCys: 0.802 ± 0.34
4.011SerAsp: 4.011 ± 0.584
4.212SerGlu: 4.212 ± 1.305
3.811SerPhe: 3.811 ± 1.249
3.41SerGly: 3.41 ± 0.833
3.61SerHis: 3.61 ± 0.713
6.619SerIle: 6.619 ± 1.359
6.819SerLys: 6.819 ± 1.03
8.424SerLeu: 8.424 ± 2.344
1.805SerMet: 1.805 ± 0.407
5.014SerAsn: 5.014 ± 1.212
1.203SerPro: 1.203 ± 0.683
2.006SerGln: 2.006 ± 1.017
3.61SerArg: 3.61 ± 0.908
3.811SerSer: 3.811 ± 0.924
4.412SerThr: 4.412 ± 0.789
4.412SerVal: 4.412 ± 0.61
0.0SerTrp: 0.0 ± 0.0
2.607SerTyr: 2.607 ± 0.865
0.0SerXaa: 0.0 ± 0.0
Thr
2.407ThrAla: 2.407 ± 0.581
1.805ThrCys: 1.805 ± 1.102
2.607ThrAsp: 2.607 ± 0.787
3.008ThrGlu: 3.008 ± 0.786
2.607ThrPhe: 2.607 ± 0.468
4.212ThrGly: 4.212 ± 0.841
1.203ThrHis: 1.203 ± 0.389
3.61ThrIle: 3.61 ± 1.182
2.808ThrLys: 2.808 ± 0.679
4.813ThrLeu: 4.813 ± 0.934
1.805ThrMet: 1.805 ± 0.542
2.206ThrAsn: 2.206 ± 0.524
1.805ThrPro: 1.805 ± 0.344
1.604ThrGln: 1.604 ± 0.688
2.607ThrArg: 2.607 ± 1.208
4.011ThrSer: 4.011 ± 0.85
4.011ThrThr: 4.011 ± 1.093
2.808ThrVal: 2.808 ± 0.69
1.203ThrTrp: 1.203 ± 0.838
3.61ThrTyr: 3.61 ± 1.484
0.0ThrXaa: 0.0 ± 0.0
Val
1.404ValAla: 1.404 ± 0.415
1.604ValCys: 1.604 ± 0.429
5.415ValAsp: 5.415 ± 0.792
5.415ValGlu: 5.415 ± 0.789
2.607ValPhe: 2.607 ± 0.806
2.607ValGly: 2.607 ± 0.893
1.604ValHis: 1.604 ± 0.648
2.407ValIle: 2.407 ± 0.772
5.816ValLys: 5.816 ± 1.568
7.02ValLeu: 7.02 ± 1.226
1.604ValMet: 1.604 ± 0.502
4.412ValAsn: 4.412 ± 0.922
2.407ValPro: 2.407 ± 0.662
1.805ValGln: 1.805 ± 0.447
4.412ValArg: 4.412 ± 0.946
5.816ValSer: 5.816 ± 0.665
3.209ValThr: 3.209 ± 0.661
5.816ValVal: 5.816 ± 0.895
0.201ValTrp: 0.201 ± 0.136
3.61ValTyr: 3.61 ± 0.799
0.0ValXaa: 0.0 ± 0.0
Trp
0.401TrpAla: 0.401 ± 0.32
0.201TrpCys: 0.201 ± 0.136
0.201TrpAsp: 0.201 ± 0.259
0.201TrpGlu: 0.201 ± 0.136
0.401TrpPhe: 0.401 ± 0.433
0.201TrpGly: 0.201 ± 0.136
0.201TrpHis: 0.201 ± 0.136
0.802TrpIle: 0.802 ± 0.377
0.602TrpLys: 0.602 ± 0.541
1.404TrpLeu: 1.404 ± 0.605
0.401TrpMet: 0.401 ± 0.385
0.602TrpAsn: 0.602 ± 0.384
0.0TrpPro: 0.0 ± 0.0
0.201TrpGln: 0.201 ± 0.268
0.802TrpArg: 0.802 ± 0.321
0.802TrpSer: 0.802 ± 0.478
0.401TrpThr: 0.401 ± 0.26
0.602TrpVal: 0.602 ± 0.494
0.0TrpTrp: 0.0 ± 0.0
0.201TrpTyr: 0.201 ± 0.136
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.805TyrAla: 1.805 ± 0.534
2.006TyrCys: 2.006 ± 0.746
4.613TyrAsp: 4.613 ± 1.092
1.203TyrGlu: 1.203 ± 0.449
2.006TyrPhe: 2.006 ± 0.625
1.604TyrGly: 1.604 ± 0.403
1.003TyrHis: 1.003 ± 0.49
2.607TyrIle: 2.607 ± 0.937
3.008TyrLys: 3.008 ± 0.661
4.011TyrLeu: 4.011 ± 0.891
1.003TyrMet: 1.003 ± 0.758
2.808TyrAsn: 2.808 ± 0.755
1.404TyrPro: 1.404 ± 0.419
1.404TyrGln: 1.404 ± 0.622
2.006TyrArg: 2.006 ± 0.636
3.209TyrSer: 3.209 ± 1.23
1.805TyrThr: 1.805 ± 0.431
2.607TyrVal: 2.607 ± 1.061
0.602TyrTrp: 0.602 ± 0.406
2.607TyrTyr: 2.607 ± 0.967
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 13 proteins (4987 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski