Amino acid dipepetide frequency for Ceraceosorus guamensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	15.034AlaAla: 15.034 ± 0.121	1.199AlaCys: 1.199 ± 0.018	5.348AlaAsp: 5.348 ± 0.043	6.175AlaGlu: 6.175 ± 0.052	3.293AlaPhe: 3.293 ± 0.03	8.089AlaGly: 8.089 ± 0.062	2.85AlaHis: 2.85 ± 0.029	3.946AlaIle: 3.946 ± 0.037	4.65AlaLys: 4.65 ± 0.045	10.166AlaLeu: 10.166 ± 0.057	2.057AlaMet: 2.057 ± 0.025	3.204AlaAsn: 3.204 ± 0.028	7.081AlaPro: 7.081 ± 0.053	5.16AlaGln: 5.16 ± 0.039	7.891AlaArg: 7.891 ± 0.057	12.37AlaSer: 12.37 ± 0.094	6.166AlaThr: 6.166 ± 0.047	5.741AlaVal: 5.741 ± 0.041	1.349AlaTrp: 1.349 ± 0.021	2.124AlaTyr: 2.124 ± 0.024	0.0AlaXaa: 0.0 ± 0.0
Cys	1.16CysAla: 1.16 ± 0.019	0.267CysCys: 0.267 ± 0.015	0.575CysAsp: 0.575 ± 0.015	0.547CysGlu: 0.547 ± 0.012	0.43CysPhe: 0.43 ± 0.011	0.807CysGly: 0.807 ± 0.017	0.266CysHis: 0.266 ± 0.009	0.509CysIle: 0.509 ± 0.011	0.449CysLys: 0.449 ± 0.013	1.058CysLeu: 1.058 ± 0.02	0.234CysMet: 0.234 ± 0.008	0.327CysAsn: 0.327 ± 0.01	0.608CysPro: 0.608 ± 0.017	0.352CysGln: 0.352 ± 0.01	0.673CysArg: 0.673 ± 0.016	0.935CysSer: 0.935 ± 0.018	0.617CysThr: 0.617 ± 0.014	0.684CysVal: 0.684 ± 0.016	0.165CysTrp: 0.165 ± 0.007	0.251CysTyr: 0.251 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	6.826AspAla: 6.826 ± 0.045	0.51AspCys: 0.51 ± 0.014	4.048AspAsp: 4.048 ± 0.047	4.581AspGlu: 4.581 ± 0.048	1.724AspPhe: 1.724 ± 0.019	4.233AspGly: 4.233 ± 0.037	1.178AspHis: 1.178 ± 0.019	1.901AspIle: 1.901 ± 0.023	1.913AspLys: 1.913 ± 0.025	4.908AspLeu: 4.908 ± 0.04	0.915AspMet: 0.915 ± 0.015	1.219AspAsn: 1.219 ± 0.018	2.968AspPro: 2.968 ± 0.03	1.909AspGln: 1.909 ± 0.022	3.105AspArg: 3.105 ± 0.032	4.08AspSer: 4.08 ± 0.042	2.418AspThr: 2.418 ± 0.026	3.838AspVal: 3.838 ± 0.031	0.774AspTrp: 0.774 ± 0.015	1.087AspTyr: 1.087 ± 0.019	0.0AspXaa: 0.0 ± 0.0
Glu	6.791GluAla: 6.791 ± 0.054	0.505GluCys: 0.505 ± 0.012	3.853GluAsp: 3.853 ± 0.04	5.787GluGlu: 5.787 ± 0.078	1.222GluPhe: 1.222 ± 0.02	4.071GluGly: 4.071 ± 0.036	1.545GluHis: 1.545 ± 0.024	2.037GluIle: 2.037 ± 0.024	2.756GluLys: 2.756 ± 0.034	5.1GluLeu: 5.1 ± 0.043	1.283GluMet: 1.283 ± 0.022	1.474GluAsn: 1.474 ± 0.019	2.424GluPro: 2.424 ± 0.028	2.791GluGln: 2.791 ± 0.033	4.705GluArg: 4.705 ± 0.04	4.309GluSer: 4.309 ± 0.041	2.748GluThr: 2.748 ± 0.026	3.294GluVal: 3.294 ± 0.032	0.795GluTrp: 0.795 ± 0.015	1.113GluTyr: 1.113 ± 0.017	0.0GluXaa: 0.0 ± 0.0
Phe	3.338PheAla: 3.338 ± 0.031	0.417PheCys: 0.417 ± 0.012	1.937PheAsp: 1.937 ± 0.02	1.844PheGlu: 1.844 ± 0.023	1.169PhePhe: 1.169 ± 0.019	2.645PheGly: 2.645 ± 0.04	0.682PheHis: 0.682 ± 0.014	1.157PheIle: 1.157 ± 0.019	1.217PheLys: 1.217 ± 0.02	2.662PheLeu: 2.662 ± 0.026	0.533PheMet: 0.533 ± 0.011	0.982PheAsn: 0.982 ± 0.016	1.468PhePro: 1.468 ± 0.02	0.986PheGln: 0.986 ± 0.017	1.64PheArg: 1.64 ± 0.024	2.568PheSer: 2.568 ± 0.027	1.554PheThr: 1.554 ± 0.022	2.077PheVal: 2.077 ± 0.023	0.451PheTrp: 0.451 ± 0.013	0.723PheTyr: 0.723 ± 0.013	0.0PheXaa: 0.0 ± 0.0
Gly	8.224GlyAla: 8.224 ± 0.059	0.743GlyCys: 0.743 ± 0.017	3.618GlyAsp: 3.618 ± 0.037	3.799GlyGlu: 3.799 ± 0.035	2.249GlyPhe: 2.249 ± 0.028	6.962GlyGly: 6.962 ± 0.078	1.824GlyHis: 1.824 ± 0.024	2.808GlyIle: 2.808 ± 0.029	3.418GlyLys: 3.418 ± 0.035	6.126GlyLeu: 6.126 ± 0.048	1.432GlyMet: 1.432 ± 0.025	2.198GlyAsn: 2.198 ± 0.025	3.902GlyPro: 3.902 ± 0.044	2.997GlyGln: 2.997 ± 0.03	4.781GlyArg: 4.781 ± 0.043	7.382GlySer: 7.382 ± 0.055	4.174GlyThr: 4.174 ± 0.037	4.171GlyVal: 4.171 ± 0.037	1.058GlyTrp: 1.058 ± 0.018	1.584GlyTyr: 1.584 ± 0.025	0.0GlyXaa: 0.0 ± 0.0
His	2.963HisAla: 2.963 ± 0.028	0.296HisCys: 0.296 ± 0.01	1.334HisAsp: 1.334 ± 0.02	1.324HisGlu: 1.324 ± 0.019	0.867HisPhe: 0.867 ± 0.015	1.815HisGly: 1.815 ± 0.022	0.986HisHis: 0.986 ± 0.023	0.997HisIle: 0.997 ± 0.016	0.867HisLys: 0.867 ± 0.015	2.59HisLeu: 2.59 ± 0.03	0.416HisMet: 0.416 ± 0.012	0.671HisAsn: 0.671 ± 0.013	1.7HisPro: 1.7 ± 0.02	1.046HisGln: 1.046 ± 0.017	1.772HisArg: 1.772 ± 0.022	2.328HisSer: 2.328 ± 0.027	1.355HisThr: 1.355 ± 0.018	1.552HisVal: 1.552 ± 0.023	0.306HisTrp: 0.306 ± 0.01	0.542HisTyr: 0.542 ± 0.014	0.0HisXaa: 0.0 ± 0.0
Ile	4.084IleAla: 4.084 ± 0.031	0.548IleCys: 0.548 ± 0.013	2.288IleAsp: 2.288 ± 0.021	2.242IleGlu: 2.242 ± 0.028	1.397IlePhe: 1.397 ± 0.021	2.658IleGly: 2.658 ± 0.033	0.902IleHis: 0.902 ± 0.014	1.603IleIle: 1.603 ± 0.026	1.664IleLys: 1.664 ± 0.024	3.392IleLeu: 3.392 ± 0.04	0.66IleMet: 0.66 ± 0.012	1.181IleAsn: 1.181 ± 0.018	2.08IlePro: 2.08 ± 0.026	1.299IleGln: 1.299 ± 0.018	2.368IleArg: 2.368 ± 0.025	3.3IleSer: 3.3 ± 0.033	1.955IleThr: 1.955 ± 0.023	2.553IleVal: 2.553 ± 0.028	0.528IleTrp: 0.528 ± 0.012	0.849IleTyr: 0.849 ± 0.017	0.0IleXaa: 0.0 ± 0.0
Lys	4.62LysAla: 4.62 ± 0.043	0.387LysCys: 0.387 ± 0.011	2.333LysAsp: 2.333 ± 0.029	2.854LysGlu: 2.854 ± 0.035	0.952LysPhe: 0.952 ± 0.017	3.012LysGly: 3.012 ± 0.03	1.08LysHis: 1.08 ± 0.018	1.44LysIle: 1.44 ± 0.02	2.441LysLys: 2.441 ± 0.044	3.53LysLeu: 3.53 ± 0.039	0.795LysMet: 0.795 ± 0.013	1.101LysAsn: 1.101 ± 0.018	2.191LysPro: 2.191 ± 0.027	1.747LysGln: 1.747 ± 0.021	3.681LysArg: 3.681 ± 0.036	3.398LysSer: 3.398 ± 0.034	2.194LysThr: 2.194 ± 0.021	2.422LysVal: 2.422 ± 0.025	0.513LysTrp: 0.513 ± 0.012	0.857LysTyr: 0.857 ± 0.015	0.0LysXaa: 0.0 ± 0.0
Leu	9.696LeuAla: 9.696 ± 0.062	1.193LeuCys: 1.193 ± 0.02	5.181LeuAsp: 5.181 ± 0.038	5.096LeuGlu: 5.096 ± 0.043	2.808LeuPhe: 2.808 ± 0.028	6.174LeuGly: 6.174 ± 0.048	2.413LeuHis: 2.413 ± 0.027	3.341LeuIle: 3.341 ± 0.032	3.523LeuLys: 3.523 ± 0.034	8.904LeuLeu: 8.904 ± 0.07	1.473LeuMet: 1.473 ± 0.02	2.607LeuAsn: 2.607 ± 0.027	5.994LeuPro: 5.994 ± 0.043	3.873LeuGln: 3.873 ± 0.041	6.612LeuArg: 6.612 ± 0.05	8.132LeuSer: 8.132 ± 0.047	4.527LeuThr: 4.527 ± 0.037	5.202LeuVal: 5.202 ± 0.047	1.038LeuTrp: 1.038 ± 0.017	1.873LeuTyr: 1.873 ± 0.023	0.0LeuXaa: 0.0 ± 0.0
Met	1.81MetAla: 1.81 ± 0.023	0.205MetCys: 0.205 ± 0.007	1.003MetAsp: 1.003 ± 0.016	0.95MetGlu: 0.95 ± 0.016	0.458MetPhe: 0.458 ± 0.012	1.273MetGly: 1.273 ± 0.021	0.498MetHis: 0.498 ± 0.012	0.657MetIle: 0.657 ± 0.014	0.644MetLys: 0.644 ± 0.013	1.796MetLeu: 1.796 ± 0.021	0.402MetMet: 0.402 ± 0.011	0.498MetAsn: 0.498 ± 0.013	1.228MetPro: 1.228 ± 0.02	0.827MetGln: 0.827 ± 0.016	1.433MetArg: 1.433 ± 0.019	1.934MetSer: 1.934 ± 0.023	1.049MetThr: 1.049 ± 0.015	0.912MetVal: 0.912 ± 0.017	0.214MetTrp: 0.214 ± 0.007	0.363MetTyr: 0.363 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	3.639AsnAla: 3.639 ± 0.032	0.277AsnCys: 0.277 ± 0.01	1.512AsnAsp: 1.512 ± 0.02	1.621AsnGlu: 1.621 ± 0.019	0.946AsnPhe: 0.946 ± 0.017	2.556AsnGly: 2.556 ± 0.031	0.641AsnHis: 0.641 ± 0.013	1.184AsnIle: 1.184 ± 0.016	1.169AsnLys: 1.169 ± 0.019	2.609AsnLeu: 2.609 ± 0.03	0.52AsnMet: 0.52 ± 0.011	0.935AsnAsn: 0.935 ± 0.018	1.734AsnPro: 1.734 ± 0.022	0.977AsnGln: 0.977 ± 0.017	1.682AsnArg: 1.682 ± 0.023	2.348AsnSer: 2.348 ± 0.027	1.596AsnThr: 1.596 ± 0.017	2.11AsnVal: 2.11 ± 0.023	0.352AsnTrp: 0.352 ± 0.009	0.58AsnTyr: 0.58 ± 0.012	0.0AsnXaa: 0.0 ± 0.0
Pro	6.781ProAla: 6.781 ± 0.05	0.519ProCys: 0.519 ± 0.013	2.796ProAsp: 2.796 ± 0.032	2.964ProGlu: 2.964 ± 0.026	1.894ProPhe: 1.894 ± 0.023	3.966ProGly: 3.966 ± 0.041	1.622ProHis: 1.622 ± 0.021	2.154ProIle: 2.154 ± 0.025	2.205ProLys: 2.205 ± 0.028	5.231ProLeu: 5.231 ± 0.04	0.935ProMet: 0.935 ± 0.017	1.858ProAsn: 1.858 ± 0.022	5.305ProPro: 5.305 ± 0.077	2.391ProGln: 2.391 ± 0.031	4.068ProArg: 4.068 ± 0.041	7.538ProSer: 7.538 ± 0.06	3.973ProThr: 3.973 ± 0.038	3.094ProVal: 3.094 ± 0.032	0.634ProTrp: 0.634 ± 0.015	1.15ProTyr: 1.15 ± 0.02	0.0ProXaa: 0.0 ± 0.0
Gln	4.835GlnAla: 4.835 ± 0.034	0.373GlnCys: 0.373 ± 0.01	2.074GlnAsp: 2.074 ± 0.023	2.417GlnGlu: 2.417 ± 0.027	0.872GlnPhe: 0.872 ± 0.015	2.903GlnGly: 2.903 ± 0.027	1.337GlnHis: 1.337 ± 0.021	1.542GlnIle: 1.542 ± 0.02	1.565GlnLys: 1.565 ± 0.021	3.554GlnLeu: 3.554 ± 0.039	0.787GlnMet: 0.787 ± 0.017	1.16GlnAsn: 1.16 ± 0.017	2.478GlnPro: 2.478 ± 0.031	2.907GlnGln: 2.907 ± 0.07	3.351GlnArg: 3.351 ± 0.038	3.779GlnSer: 3.779 ± 0.032	2.259GlnThr: 2.259 ± 0.024	2.222GlnVal: 2.222 ± 0.023	0.456GlnTrp: 0.456 ± 0.01	0.803GlnTyr: 0.803 ± 0.016	0.0GlnXaa: 0.0 ± 0.0
Arg	7.552ArgAla: 7.552 ± 0.06	0.793ArgCys: 0.793 ± 0.016	3.559ArgAsp: 3.559 ± 0.033	4.099ArgGlu: 4.099 ± 0.038	2.061ArgPhe: 2.061 ± 0.022	4.715ArgGly: 4.715 ± 0.044	1.784ArgHis: 1.784 ± 0.022	2.793ArgIle: 2.793 ± 0.032	3.371ArgLys: 3.371 ± 0.035	6.271ArgLeu: 6.271 ± 0.047	1.408ArgMet: 1.408 ± 0.018	2.096ArgAsn: 2.096 ± 0.023	4.191ArgPro: 4.191 ± 0.043	2.948ArgGln: 2.948 ± 0.028	6.533ArgArg: 6.533 ± 0.061	6.941ArgSer: 6.941 ± 0.058	3.748ArgThr: 3.748 ± 0.035	3.63ArgVal: 3.63 ± 0.031	0.943ArgTrp: 0.943 ± 0.014	1.379ArgTyr: 1.379 ± 0.019	0.0ArgXaa: 0.0 ± 0.0
Ser	11.502SerAla: 11.502 ± 0.077	0.858SerCys: 0.858 ± 0.015	4.712SerAsp: 4.712 ± 0.037	4.471SerGlu: 4.471 ± 0.043	2.842SerPhe: 2.842 ± 0.028	7.193SerGly: 7.193 ± 0.051	2.394SerHis: 2.394 ± 0.027	3.644SerIle: 3.644 ± 0.035	3.871SerLys: 3.871 ± 0.038	8.002SerLeu: 8.002 ± 0.053	1.675SerMet: 1.675 ± 0.024	3.099SerAsn: 3.099 ± 0.03	6.304SerPro: 6.304 ± 0.07	3.696SerGln: 3.696 ± 0.033	6.738SerArg: 6.738 ± 0.06	13.374SerSer: 13.374 ± 0.128	6.662SerThr: 6.662 ± 0.055	4.908SerVal: 4.908 ± 0.043	1.021SerTrp: 1.021 ± 0.015	1.684SerTyr: 1.684 ± 0.021	0.0SerXaa: 0.0 ± 0.0
Thr	5.821ThrAla: 5.821 ± 0.045	0.663ThrCys: 0.663 ± 0.014	2.487ThrAsp: 2.487 ± 0.026	2.45ThrGlu: 2.45 ± 0.026	1.927ThrPhe: 1.927 ± 0.023	3.89ThrGly: 3.89 ± 0.034	1.387ThrHis: 1.387 ± 0.021	2.182ThrIle: 2.182 ± 0.026	1.981ThrLys: 1.981 ± 0.023	5.279ThrLeu: 5.279 ± 0.039	0.95ThrMet: 0.95 ± 0.016	1.604ThrAsn: 1.604 ± 0.02	4.216ThrPro: 4.216 ± 0.047	2.048ThrGln: 2.048 ± 0.025	3.586ThrArg: 3.586 ± 0.033	6.652ThrSer: 6.652 ± 0.06	3.58ThrThr: 3.58 ± 0.043	2.843ThrVal: 2.843 ± 0.031	0.695ThrTrp: 0.695 ± 0.014	1.148ThrTyr: 1.148 ± 0.019	0.0ThrXaa: 0.0 ± 0.0
Val	5.932ValAla: 5.932 ± 0.047	0.707ValCys: 0.707 ± 0.013	3.498ValAsp: 3.498 ± 0.034	3.561ValGlu: 3.561 ± 0.037	1.78ValPhe: 1.78 ± 0.023	4.09ValGly: 4.09 ± 0.035	1.477ValHis: 1.477 ± 0.02	2.249ValIle: 2.249 ± 0.03	2.464ValLys: 2.464 ± 0.028	5.359ValLeu: 5.359 ± 0.049	1.002ValMet: 1.002 ± 0.018	1.613ValAsn: 1.613 ± 0.022	3.608ValPro: 3.608 ± 0.031	2.429ValGln: 2.429 ± 0.027	3.945ValArg: 3.945 ± 0.034	4.569ValSer: 4.569 ± 0.032	2.881ValThr: 2.881 ± 0.029	3.705ValVal: 3.705 ± 0.036	0.792ValTrp: 0.792 ± 0.015	1.222ValTyr: 1.222 ± 0.015	0.0ValXaa: 0.0 ± 0.0
Trp	1.134TrpAla: 1.134 ± 0.018	0.175TrpCys: 0.175 ± 0.007	0.732TrpAsp: 0.732 ± 0.015	0.659TrpGlu: 0.659 ± 0.014	0.382TrpPhe: 0.382 ± 0.011	0.762TrpGly: 0.762 ± 0.014	0.338TrpHis: 0.338 ± 0.009	0.582TrpIle: 0.582 ± 0.013	0.577TrpLys: 0.577 ± 0.014	1.23TrpLeu: 1.23 ± 0.018	0.289TrpMet: 0.289 ± 0.009	0.486TrpAsn: 0.486 ± 0.013	0.568TrpPro: 0.568 ± 0.012	0.576TrpGln: 0.576 ± 0.013	0.985TrpArg: 0.985 ± 0.017	1.151TrpSer: 1.151 ± 0.018	0.807TrpThr: 0.807 ± 0.015	0.647TrpVal: 0.647 ± 0.015	0.225TrpTrp: 0.225 ± 0.008	0.293TrpTyr: 0.293 ± 0.01	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.15TyrAla: 2.15 ± 0.022	0.279TyrCys: 0.279 ± 0.008	1.248TyrAsp: 1.248 ± 0.019	1.162TyrGlu: 1.162 ± 0.016	0.777TyrPhe: 0.777 ± 0.015	1.637TyrGly: 1.637 ± 0.024	0.522TyrHis: 0.522 ± 0.013	0.823TyrIle: 0.823 ± 0.015	0.803TyrLys: 0.803 ± 0.014	1.893TyrLeu: 1.893 ± 0.02	0.389TyrMet: 0.389 ± 0.009	0.676TyrAsn: 0.676 ± 0.016	1.032TyrPro: 1.032 ± 0.016	0.715TyrGln: 0.715 ± 0.015	1.265TyrArg: 1.265 ± 0.018	1.564TyrSer: 1.564 ± 0.024	1.125TyrThr: 1.125 ± 0.018	1.278TyrVal: 1.278 ± 0.02	0.288TyrTrp: 0.288 ± 0.009	0.617TyrTyr: 0.617 ± 0.058	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.005XaaXaa: 0.005 ± 0.003

Statistics based on 7822 proteins (4077528 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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