Cotia virus

Taxonomy: Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes; Chitovirales; Poxviridae; Chordopoxvirinae; Oryzopoxvirus

Average proteome isoelectric point is 6.97

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 170 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A097IW10|A0A097IW10_9POXV CD47-like protein OS=Cotia virus OX=39444 GN=146 PE=4 SV=1
MM1 pKa = 6.83EE2 pKa = 4.55TGIIIVIVITTIIAILLFCYY22 pKa = 9.52SVCICIYY29 pKa = 8.51YY30 pKa = 8.21TVPLYY35 pKa = 10.65YY36 pKa = 10.42KK37 pKa = 10.3KK38 pKa = 10.5NKK40 pKa = 8.51KK41 pKa = 9.98KK42 pKa = 10.66KK43 pKa = 9.37IIKK46 pKa = 10.07LNEE49 pKa = 3.83IYY51 pKa = 10.69FGTNDD56 pKa = 3.13INKK59 pKa = 9.72KK60 pKa = 8.04SVEE63 pKa = 4.24YY64 pKa = 8.71ITNYY68 pKa = 7.96EE69 pKa = 3.94TDD71 pKa = 4.32DD72 pKa = 3.81IGNKK76 pKa = 10.01SVDD79 pKa = 2.83ITSYY83 pKa = 11.54DD84 pKa = 3.62EE85 pKa = 3.99NDD87 pKa = 3.85NYY89 pKa = 11.48NKK91 pKa = 10.79DD92 pKa = 3.38EE93 pKa = 4.92FIEE96 pKa = 4.18EE97 pKa = 3.9NEE99 pKa = 3.99YY100 pKa = 10.63WEE102 pKa = 5.72DD103 pKa = 3.89DD104 pKa = 4.44DD105 pKa = 6.04ISTSMSVAKK114 pKa = 10.25YY115 pKa = 9.74DD116 pKa = 3.66EE117 pKa = 5.05EE118 pKa = 5.89IIEE121 pKa = 4.72PIYY124 pKa = 11.32ANISNDD130 pKa = 3.67DD131 pKa = 3.89VINSYY136 pKa = 11.52DD137 pKa = 4.65KK138 pKa = 10.79IDD140 pKa = 3.89NNIKK144 pKa = 10.4DD145 pKa = 4.39LYY147 pKa = 11.12AIINTDD153 pKa = 3.19TNKK156 pKa = 10.56NIEE159 pKa = 4.23NDD161 pKa = 4.51DD162 pKa = 4.1EE163 pKa = 6.22IEE165 pKa = 4.26DD166 pKa = 4.28KK167 pKa = 11.05KK168 pKa = 11.28SSSNNHH174 pKa = 5.05VNVSLHH180 pKa = 6.33KK181 pKa = 9.55EE182 pKa = 3.87SEE184 pKa = 4.59PIYY187 pKa = 9.09MIPPDD192 pKa = 4.84AINN195 pKa = 3.24

Molecular weight: 22.65 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A097IVL5|A0A097IVL5_9POXV Ribonucleoside-diphosphate reductase small chain OS=Cotia virus OX=39444 GN=37 PE=3 SV=1
MM1 pKa = 7.35SSKK4 pKa = 10.6GGSSGGMWSVFIHH17 pKa = 5.83GHH19 pKa = 6.32DD20 pKa = 3.77GTVKK24 pKa = 10.32GSKK27 pKa = 9.24TYY29 pKa = 10.24TSLGGGGVKK38 pKa = 10.18SGVNGGVNGGVSSGTRR54 pKa = 11.84KK55 pKa = 9.43II56 pKa = 3.71

Molecular weight: 5.37 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

170

0

170

52575

34

1842

309.3

35.96

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

2.195 ± 0.1

1.986 ± 0.09

6.4 ± 0.109

4.968 ± 0.134

5.08 ± 0.138

3.408 ± 0.114

1.581 ± 0.058

12.369 ± 0.267

9.132 ± 0.148

8.683 ± 0.157

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.244 ± 0.068

9.552 ± 0.216

2.718 ± 0.111

1.653 ± 0.085

2.868 ± 0.116

7.582 ± 0.171

5.514 ± 0.144

5.253 ± 0.12

0.597 ± 0.042

6.216 ± 0.149
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski