Canine oral papillomavirus (strain Y62) (COPV)

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Lambdapapillomavirus; Lambdapapillomavirus 2

Average proteome isoelectric point is 6.16

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 7 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>sp|Q89808|VE6_COPV6 Protein E6 OS=Canine oral papillomavirus (strain Y62) OX=766192 GN=E6 PE=3 SV=1
MM1 pKa = 7.71IGQCATLLDD10 pKa = 3.93IVLTEE15 pKa = 4.01QPEE18 pKa = 4.57PIDD21 pKa = 3.79LQCYY25 pKa = 7.01EE26 pKa = 4.54QLPSSDD32 pKa = 3.59EE33 pKa = 4.11EE34 pKa = 4.39EE35 pKa = 4.54EE36 pKa = 4.29EE37 pKa = 4.74EE38 pKa = 5.02EE39 pKa = 4.05PTEE42 pKa = 4.14KK43 pKa = 10.45NVYY46 pKa = 9.9RR47 pKa = 11.84IEE49 pKa = 4.21AACGFCGKK57 pKa = 9.69GVRR60 pKa = 11.84FFCLSQKK67 pKa = 10.56EE68 pKa = 4.28DD69 pKa = 3.54LRR71 pKa = 11.84VLQVTLLSLSLVCTTCVQTAKK92 pKa = 10.31LDD94 pKa = 3.57HH95 pKa = 6.66GGG97 pKa = 3.36

Molecular weight: 10.8 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>sp|Q89536|VE1_COPV6 Replication protein E1 OS=Canine oral papillomavirus (strain Y62) OX=766192 GN=E1 PE=3 SV=1
MM1 pKa = 7.61EE2 pKa = 5.69KK3 pKa = 10.51LSEE6 pKa = 4.4ALDD9 pKa = 3.92LLQEE13 pKa = 4.44EE14 pKa = 4.93LLSLYY19 pKa = 8.59EE20 pKa = 4.1QNSQSLADD28 pKa = 4.1QSRR31 pKa = 11.84HH32 pKa = 3.67WSLLRR37 pKa = 11.84KK38 pKa = 9.21EE39 pKa = 4.34QVLLYY44 pKa = 8.49YY45 pKa = 10.85ARR47 pKa = 11.84GKK49 pKa = 10.76GIMRR53 pKa = 11.84IGMQPVPPQSVSQAKK68 pKa = 9.62AKK70 pKa = 10.09QAIEE74 pKa = 3.58QSLYY78 pKa = 10.2IDD80 pKa = 4.01SLLHH84 pKa = 5.88SKK86 pKa = 9.78YY87 pKa = 10.94ANEE90 pKa = 3.95PWTLCDD96 pKa = 3.24TSRR99 pKa = 11.84EE100 pKa = 4.0RR101 pKa = 11.84LVAEE105 pKa = 4.0PAYY108 pKa = 9.42TFKK111 pKa = 11.02KK112 pKa = 10.11GGKK115 pKa = 9.42QIDD118 pKa = 3.7VRR120 pKa = 11.84YY121 pKa = 10.06GDD123 pKa = 3.61SEE125 pKa = 4.5EE126 pKa = 4.66NIVRR130 pKa = 11.84YY131 pKa = 8.48VLWLDD136 pKa = 4.01IYY138 pKa = 11.14YY139 pKa = 10.07QDD141 pKa = 5.89EE142 pKa = 4.17FDD144 pKa = 3.62TWEE147 pKa = 4.17KK148 pKa = 11.1AHH150 pKa = 6.75GKK152 pKa = 9.6LDD154 pKa = 3.92HH155 pKa = 6.94KK156 pKa = 10.75GLSYY160 pKa = 10.15MHH162 pKa = 6.88GTQQVYY168 pKa = 9.19YY169 pKa = 10.84VDD171 pKa = 5.16FEE173 pKa = 4.5EE174 pKa = 4.64EE175 pKa = 3.89ANKK178 pKa = 10.51YY179 pKa = 10.61SEE181 pKa = 4.08TGKK184 pKa = 10.83YY185 pKa = 9.66EE186 pKa = 4.11ILNQPTTIPTTSAAGTSGPEE206 pKa = 4.12LPGHH210 pKa = 5.73SASGSGACSLTPRR223 pKa = 11.84KK224 pKa = 10.08GPSRR228 pKa = 11.84RR229 pKa = 11.84PGRR232 pKa = 11.84RR233 pKa = 11.84SSRR236 pKa = 11.84FPRR239 pKa = 11.84RR240 pKa = 11.84SGGRR244 pKa = 11.84GRR246 pKa = 11.84LGRR249 pKa = 11.84GGSGEE254 pKa = 5.33LPPQPQPSSSWSPPSPQQVGSKK276 pKa = 9.47HH277 pKa = 4.77QLRR280 pKa = 11.84TTSSAGGRR288 pKa = 11.84LGRR291 pKa = 11.84LLQEE295 pKa = 5.1AYY297 pKa = 10.24DD298 pKa = 3.96PPVLVLAGDD307 pKa = 4.11PNSLKK312 pKa = 10.49CIRR315 pKa = 11.84YY316 pKa = 9.01RR317 pKa = 11.84LSHH320 pKa = 5.77KK321 pKa = 10.37HH322 pKa = 5.52RR323 pKa = 11.84GLYY326 pKa = 10.33LGASTTWKK334 pKa = 6.73WTSGGDD340 pKa = 3.44GASKK344 pKa = 10.34HH345 pKa = 6.38DD346 pKa = 3.92RR347 pKa = 11.84GSARR351 pKa = 11.84MLLAFLSDD359 pKa = 3.52QQRR362 pKa = 11.84EE363 pKa = 4.13DD364 pKa = 3.32FMDD367 pKa = 3.59RR368 pKa = 11.84VTFPKK373 pKa = 9.87SVRR376 pKa = 11.84VFRR379 pKa = 11.84GGLDD383 pKa = 3.34EE384 pKa = 4.83LL385 pKa = 4.75

Molecular weight: 43.1 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

7

0

7

2357

97

597

336.7

37.8

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.261 ± 0.527

2.249 ± 0.824

6.067 ± 0.411

6.576 ± 0.661

4.497 ± 0.592

7.0 ± 0.647

2.333 ± 0.161

4.328 ± 0.934

5.388 ± 0.574

9.504 ± 1.108

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.4 ± 0.235

3.521 ± 0.707

7.0 ± 1.232

4.455 ± 0.407

6.194 ± 0.509

8.401 ± 0.864

5.685 ± 0.373

5.685 ± 0.607

1.358 ± 0.293

3.097 ± 0.465
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski