Amino acid dipepetide frequency for Tortoise microvirus 35

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.108AlaAla: 4.108 ± 1.773
0.822AlaCys: 0.822 ± 0.796
2.465AlaAsp: 2.465 ± 1.02
3.287AlaGlu: 3.287 ± 1.988
0.822AlaPhe: 0.822 ± 0.771
5.752AlaGly: 5.752 ± 2.323
1.643AlaHis: 1.643 ± 0.57
3.287AlaIle: 3.287 ± 1.205
2.465AlaLys: 2.465 ± 2.166
8.217AlaLeu: 8.217 ± 6.585
0.822AlaMet: 0.822 ± 0.544
4.93AlaAsn: 4.93 ± 1.711
4.93AlaPro: 4.93 ± 2.271
4.93AlaGln: 4.93 ± 1.711
5.752AlaArg: 5.752 ± 0.51
6.574AlaSer: 6.574 ± 3.008
4.108AlaThr: 4.108 ± 1.151
1.643AlaVal: 1.643 ± 1.087
0.0AlaTrp: 0.0 ± 0.0
0.822AlaTyr: 0.822 ± 0.544
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
0.822CysGly: 0.822 ± 0.796
0.0CysHis: 0.0 ± 0.0
0.822CysIle: 0.822 ± 1.083
1.643CysLys: 1.643 ± 1.592
0.822CysLeu: 0.822 ± 0.544
0.822CysMet: 0.822 ± 0.544
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
1.643CysSer: 1.643 ± 1.592
0.822CysThr: 0.822 ± 0.796
0.0CysVal: 0.0 ± 0.0
1.643CysTrp: 1.643 ± 1.592
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
4.108AspAla: 4.108 ± 1.151
1.643AspCys: 1.643 ± 1.221
5.752AspAsp: 5.752 ± 3.181
1.643AspGlu: 1.643 ± 0.997
5.752AspPhe: 5.752 ± 2.707
1.643AspGly: 1.643 ± 0.741
0.0AspHis: 0.0 ± 0.0
3.287AspIle: 3.287 ± 1.205
4.93AspLys: 4.93 ± 0.959
4.93AspLeu: 4.93 ± 1.848
1.643AspMet: 1.643 ± 1.684
2.465AspAsn: 2.465 ± 1.389
3.287AspPro: 3.287 ± 0.942
3.287AspGln: 3.287 ± 1.141
3.287AspArg: 3.287 ± 1.828
4.93AspSer: 4.93 ± 1.928
2.465AspThr: 2.465 ± 1.027
2.465AspVal: 2.465 ± 1.027
0.822AspTrp: 0.822 ± 0.544
5.752AspTyr: 5.752 ± 1.747
0.0AspXaa: 0.0 ± 0.0
Glu
1.643GluAla: 1.643 ± 0.997
0.0GluCys: 0.0 ± 0.0
2.465GluAsp: 2.465 ± 0.638
3.287GluGlu: 3.287 ± 3.347
2.465GluPhe: 2.465 ± 1.631
1.643GluGly: 1.643 ± 1.087
0.822GluHis: 0.822 ± 0.544
1.643GluIle: 1.643 ± 1.087
5.752GluLys: 5.752 ± 0.772
2.465GluLeu: 2.465 ± 1.02
0.822GluMet: 0.822 ± 0.771
3.287GluAsn: 3.287 ± 0.942
2.465GluPro: 2.465 ± 2.307
0.822GluGln: 0.822 ± 0.544
4.93GluArg: 4.93 ± 2.791
5.752GluSer: 5.752 ± 3.096
2.465GluThr: 2.465 ± 0.638
3.287GluVal: 3.287 ± 2.174
0.0GluTrp: 0.0 ± 0.0
7.395GluTyr: 7.395 ± 1.144
0.0GluXaa: 0.0 ± 0.0
Phe
3.287PheAla: 3.287 ± 0.589
0.822PheCys: 0.822 ± 0.796
8.217PheAsp: 8.217 ± 1.038
0.822PheGlu: 0.822 ± 0.771
3.287PhePhe: 3.287 ± 1.481
3.287PheGly: 3.287 ± 0.942
0.822PheHis: 0.822 ± 0.796
1.643PheIle: 1.643 ± 0.741
1.643PheLys: 1.643 ± 1.087
2.465PheLeu: 2.465 ± 0.964
0.822PheMet: 0.822 ± 0.796
4.108PheAsn: 4.108 ± 1.921
0.822PhePro: 0.822 ± 0.544
0.822PheGln: 0.822 ± 0.771
5.752PheArg: 5.752 ± 1.928
0.822PheSer: 0.822 ± 0.544
2.465PheThr: 2.465 ± 1.631
4.93PheVal: 4.93 ± 1.671
1.643PheTrp: 1.643 ± 1.087
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
4.108GlyAla: 4.108 ± 1.773
0.0GlyCys: 0.0 ± 0.0
2.465GlyAsp: 2.465 ± 1.631
5.752GlyGlu: 5.752 ± 2.421
2.465GlyPhe: 2.465 ± 0.638
4.93GlyGly: 4.93 ± 3.262
0.822GlyHis: 0.822 ± 0.544
3.287GlyIle: 3.287 ± 1.249
3.287GlyLys: 3.287 ± 1.481
4.93GlyLeu: 4.93 ± 1.609
0.0GlyMet: 0.0 ± 0.0
1.643GlyAsn: 1.643 ± 1.336
1.643GlyPro: 1.643 ± 0.997
4.108GlyGln: 4.108 ± 1.366
4.93GlyArg: 4.93 ± 1.211
2.465GlySer: 2.465 ± 1.438
6.574GlyThr: 6.574 ± 2.498
2.465GlyVal: 2.465 ± 1.185
0.0GlyTrp: 0.0 ± 0.0
2.465GlyTyr: 2.465 ± 1.027
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.822HisGlu: 0.822 ± 0.544
2.465HisPhe: 2.465 ± 1.027
1.643HisGly: 1.643 ± 1.087
0.0HisHis: 0.0 ± 0.0
0.822HisIle: 0.822 ± 0.771
1.643HisLys: 1.643 ± 0.741
4.108HisLeu: 4.108 ± 1.147
0.822HisMet: 0.822 ± 0.544
0.0HisAsn: 0.0 ± 0.0
0.0HisPro: 0.0 ± 0.0
0.822HisGln: 0.822 ± 0.544
0.822HisArg: 0.822 ± 0.544
0.0HisSer: 0.0 ± 0.0
0.0HisThr: 0.0 ± 0.0
0.822HisVal: 0.822 ± 0.544
0.0HisTrp: 0.0 ± 0.0
2.465HisTyr: 2.465 ± 1.438
0.0HisXaa: 0.0 ± 0.0
Ile
0.822IleAla: 0.822 ± 0.771
0.0IleCys: 0.0 ± 0.0
2.465IleAsp: 2.465 ± 1.02
1.643IleGlu: 1.643 ± 0.57
2.465IlePhe: 2.465 ± 1.631
4.108IleGly: 4.108 ± 0.911
0.822IleHis: 0.822 ± 0.544
1.643IleIle: 1.643 ± 0.741
2.465IleLys: 2.465 ± 0.638
3.287IleLeu: 3.287 ± 0.589
1.643IleMet: 1.643 ± 0.652
4.93IleAsn: 4.93 ± 1.275
1.643IlePro: 1.643 ± 0.741
0.822IleGln: 0.822 ± 0.771
4.93IleArg: 4.93 ± 2.222
3.287IleSer: 3.287 ± 1.141
3.287IleThr: 3.287 ± 1.205
4.93IleVal: 4.93 ± 1.422
0.822IleTrp: 0.822 ± 0.544
3.287IleTyr: 3.287 ± 1.249
0.0IleXaa: 0.0 ± 0.0
Lys
2.465LysAla: 2.465 ± 2.313
0.822LysCys: 0.822 ± 0.796
1.643LysAsp: 1.643 ± 0.57
2.465LysGlu: 2.465 ± 2.01
4.108LysPhe: 4.108 ± 2.122
0.822LysGly: 0.822 ± 1.083
0.0LysHis: 0.0 ± 0.0
3.287LysIle: 3.287 ± 1.325
1.643LysLys: 1.643 ± 0.741
6.574LysLeu: 6.574 ± 2.842
1.643LysMet: 1.643 ± 0.494
3.287LysAsn: 3.287 ± 0.589
2.465LysPro: 2.465 ± 1.669
0.0LysGln: 0.0 ± 0.0
4.108LysArg: 4.108 ± 1.355
0.822LysSer: 0.822 ± 0.796
4.93LysThr: 4.93 ± 1.211
2.465LysVal: 2.465 ± 1.753
0.0LysTrp: 0.0 ± 0.0
5.752LysTyr: 5.752 ± 2.421
0.0LysXaa: 0.0 ± 0.0
Leu
8.217LeuAla: 8.217 ± 2.766
2.465LeuCys: 2.465 ± 1.438
4.93LeuAsp: 4.93 ± 1.928
4.108LeuGlu: 4.108 ± 2.168
5.752LeuPhe: 5.752 ± 3.627
8.217LeuGly: 8.217 ± 1.511
0.0LeuHis: 0.0 ± 0.0
4.93LeuIle: 4.93 ± 2.667
5.752LeuLys: 5.752 ± 3.379
3.287LeuLeu: 3.287 ± 0.896
0.822LeuMet: 0.822 ± 0.609
4.108LeuAsn: 4.108 ± 1.284
5.752LeuPro: 5.752 ± 2.144
7.395LeuGln: 7.395 ± 2.772
5.752LeuArg: 5.752 ± 1.921
2.465LeuSer: 2.465 ± 1.438
6.574LeuThr: 6.574 ± 2.502
3.287LeuVal: 3.287 ± 1.481
0.0LeuTrp: 0.0 ± 0.0
2.465LeuTyr: 2.465 ± 1.631
0.0LeuXaa: 0.0 ± 0.0
Met
4.108MetAla: 4.108 ± 1.75
0.0MetCys: 0.0 ± 0.0
0.822MetAsp: 0.822 ± 0.796
0.822MetGlu: 0.822 ± 0.544
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
0.822MetHis: 0.822 ± 0.544
0.0MetIle: 0.0 ± 0.0
1.643MetLys: 1.643 ± 1.592
0.822MetLeu: 0.822 ± 0.544
0.0MetMet: 0.0 ± 0.0
0.822MetAsn: 0.822 ± 0.796
0.822MetPro: 0.822 ± 0.544
2.465MetGln: 2.465 ± 0.804
0.822MetArg: 0.822 ± 0.796
2.465MetSer: 2.465 ± 1.185
0.0MetThr: 0.0 ± 0.0
0.822MetVal: 0.822 ± 0.796
0.822MetTrp: 0.822 ± 0.771
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.287AsnAla: 3.287 ± 1.988
0.822AsnCys: 0.822 ± 0.796
4.93AsnAsp: 4.93 ± 0.876
7.395AsnGlu: 7.395 ± 1.009
0.822AsnPhe: 0.822 ± 0.796
4.108AsnGly: 4.108 ± 0.938
1.643AsnHis: 1.643 ± 0.741
2.465AsnIle: 2.465 ± 1.185
3.287AsnLys: 3.287 ± 1.988
4.93AsnLeu: 4.93 ± 2.485
0.822AsnMet: 0.822 ± 0.544
0.822AsnAsn: 0.822 ± 0.771
0.822AsnPro: 0.822 ± 0.771
3.287AsnGln: 3.287 ± 2.338
6.574AsnArg: 6.574 ± 2.281
9.039AsnSer: 9.039 ± 2.068
2.465AsnThr: 2.465 ± 1.631
1.643AsnVal: 1.643 ± 0.741
0.0AsnTrp: 0.0 ± 0.0
3.287AsnTyr: 3.287 ± 2.269
0.0AsnXaa: 0.0 ± 0.0
Pro
1.643ProAla: 1.643 ± 1.028
0.822ProCys: 0.822 ± 0.544
4.93ProAsp: 4.93 ± 2.99
2.465ProGlu: 2.465 ± 1.631
0.822ProPhe: 0.822 ± 0.544
1.643ProGly: 1.643 ± 1.087
1.643ProHis: 1.643 ± 1.592
3.287ProIle: 3.287 ± 1.466
2.465ProLys: 2.465 ± 1.027
4.108ProLeu: 4.108 ± 2.313
1.643ProMet: 1.643 ± 1.087
3.287ProAsn: 3.287 ± 1.249
0.0ProPro: 0.0 ± 0.0
3.287ProGln: 3.287 ± 0.589
5.752ProArg: 5.752 ± 1.993
1.643ProSer: 1.643 ± 2.166
3.287ProThr: 3.287 ± 0.942
4.108ProVal: 4.108 ± 1.959
0.822ProTrp: 0.822 ± 0.544
1.643ProTyr: 1.643 ± 1.336
0.0ProXaa: 0.0 ± 0.0
Gln
7.395GlnAla: 7.395 ± 4.733
0.0GlnCys: 0.0 ± 0.0
0.822GlnAsp: 0.822 ± 0.544
2.465GlnGlu: 2.465 ± 1.633
1.643GlnPhe: 1.643 ± 1.028
2.465GlnGly: 2.465 ± 1.027
0.822GlnHis: 0.822 ± 0.771
4.108GlnIle: 4.108 ± 1.773
0.822GlnLys: 0.822 ± 0.771
4.108GlnLeu: 4.108 ± 0.911
0.0GlnMet: 0.0 ± 0.0
4.108GlnAsn: 4.108 ± 1.773
2.465GlnPro: 2.465 ± 1.185
0.822GlnGln: 0.822 ± 0.771
3.287GlnArg: 3.287 ± 0.942
3.287GlnSer: 3.287 ± 1.141
0.822GlnThr: 0.822 ± 0.544
0.822GlnVal: 0.822 ± 0.544
0.0GlnTrp: 0.0 ± 0.0
3.287GlnTyr: 3.287 ± 1.886
0.0GlnXaa: 0.0 ± 0.0
Arg
7.395ArgAla: 7.395 ± 2.98
0.0ArgCys: 0.0 ± 0.0
7.395ArgAsp: 7.395 ± 2.86
2.465ArgGlu: 2.465 ± 2.307
4.108ArgPhe: 4.108 ± 1.622
2.465ArgGly: 2.465 ± 1.027
1.643ArgHis: 1.643 ± 0.741
4.108ArgIle: 4.108 ± 1.147
2.465ArgLys: 2.465 ± 0.638
9.039ArgLeu: 9.039 ± 1.816
0.822ArgMet: 0.822 ± 0.544
3.287ArgAsn: 3.287 ± 0.589
4.93ArgPro: 4.93 ± 2.053
4.108ArgGln: 4.108 ± 1.366
6.574ArgArg: 6.574 ± 2.115
4.108ArgSer: 4.108 ± 1.284
2.465ArgThr: 2.465 ± 0.964
2.465ArgVal: 2.465 ± 1.631
0.0ArgTrp: 0.0 ± 0.0
6.574ArgTyr: 6.574 ± 2.502
0.0ArgXaa: 0.0 ± 0.0
Ser
6.574SerAla: 6.574 ± 2.066
0.0SerCys: 0.0 ± 0.0
4.108SerAsp: 4.108 ± 0.911
6.574SerGlu: 6.574 ± 3.289
4.93SerPhe: 4.93 ± 1.671
3.287SerGly: 3.287 ± 0.589
1.643SerHis: 1.643 ± 1.087
5.752SerIle: 5.752 ± 2.421
2.465SerLys: 2.465 ± 1.753
9.039SerLeu: 9.039 ± 3.134
1.643SerMet: 1.643 ± 1.592
4.93SerAsn: 4.93 ± 1.415
4.93SerPro: 4.93 ± 1.848
1.643SerGln: 1.643 ± 1.542
3.287SerArg: 3.287 ± 2.269
7.395SerSer: 7.395 ± 2.714
3.287SerThr: 3.287 ± 1.325
5.752SerVal: 5.752 ± 1.685
0.822SerTrp: 0.822 ± 0.544
3.287SerTyr: 3.287 ± 0.942
0.0SerXaa: 0.0 ± 0.0
Thr
2.465ThrAla: 2.465 ± 1.242
0.0ThrCys: 0.0 ± 0.0
3.287ThrAsp: 3.287 ± 0.98
0.822ThrGlu: 0.822 ± 1.083
1.643ThrPhe: 1.643 ± 0.57
4.108ThrGly: 4.108 ± 0.938
0.822ThrHis: 0.822 ± 0.544
2.465ThrIle: 2.465 ± 0.804
0.822ThrLys: 0.822 ± 0.771
6.574ThrLeu: 6.574 ± 2.716
0.0ThrMet: 0.0 ± 0.0
4.108ThrAsn: 4.108 ± 1.773
4.93ThrPro: 4.93 ± 3.262
1.643ThrGln: 1.643 ± 0.997
2.465ThrArg: 2.465 ± 1.633
9.86ThrSer: 9.86 ± 3.449
0.822ThrThr: 0.822 ± 1.083
4.108ThrVal: 4.108 ± 1.863
0.0ThrTrp: 0.0 ± 0.0
0.822ThrTyr: 0.822 ± 0.796
0.0ThrXaa: 0.0 ± 0.0
Val
3.287ValAla: 3.287 ± 1.481
0.0ValCys: 0.0 ± 0.0
3.287ValAsp: 3.287 ± 1.912
3.287ValGlu: 3.287 ± 2.174
2.465ValPhe: 2.465 ± 1.631
4.108ValGly: 4.108 ± 1.706
1.643ValHis: 1.643 ± 1.087
0.822ValIle: 0.822 ± 0.544
1.643ValLys: 1.643 ± 0.997
2.465ValLeu: 2.465 ± 1.027
0.822ValMet: 0.822 ± 0.544
4.108ValAsn: 4.108 ± 2.091
5.752ValPro: 5.752 ± 2.024
0.0ValGln: 0.0 ± 0.0
2.465ValArg: 2.465 ± 1.027
9.86ValSer: 9.86 ± 2.105
0.822ValThr: 0.822 ± 0.544
2.465ValVal: 2.465 ± 0.638
0.822ValTrp: 0.822 ± 0.544
0.0ValTyr: 0.0 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.822TrpAla: 0.822 ± 0.544
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
1.643TrpGlu: 1.643 ± 1.087
0.822TrpPhe: 0.822 ± 0.796
0.0TrpGly: 0.0 ± 0.0
0.822TrpHis: 0.822 ± 0.544
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.822TrpLeu: 0.822 ± 0.544
0.822TrpMet: 0.822 ± 0.544
0.822TrpAsn: 0.822 ± 0.771
0.822TrpPro: 0.822 ± 0.544
0.0TrpGln: 0.0 ± 0.0
0.822TrpArg: 0.822 ± 0.544
1.643TrpSer: 1.643 ± 0.741
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.643TyrAla: 1.643 ± 0.997
0.822TyrCys: 0.822 ± 0.796
4.93TyrAsp: 4.93 ± 1.593
1.643TyrGlu: 1.643 ± 1.221
1.643TyrPhe: 1.643 ± 1.087
3.287TyrGly: 3.287 ± 0.896
0.822TyrHis: 0.822 ± 0.796
1.643TyrIle: 1.643 ± 1.087
2.465TyrLys: 2.465 ± 0.638
3.287TyrLeu: 3.287 ± 0.896
0.822TyrMet: 0.822 ± 0.544
7.395TyrAsn: 7.395 ± 1.791
0.822TyrPro: 0.822 ± 1.083
3.287TyrGln: 3.287 ± 1.141
4.108TyrArg: 4.108 ± 2.091
3.287TyrSer: 3.287 ± 1.912
4.108TyrThr: 4.108 ± 1.284
1.643TyrVal: 1.643 ± 0.741
1.643TyrTrp: 1.643 ± 1.087
4.93TyrTyr: 4.93 ± 2.064
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (1218 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski